LOCUS       NZ_JAKRKC020000002     23641 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Actinomadura luzonensis strain ATCC 31491 Contig00006, whole genome
            shotgun sequence.
ACCESSION   NZ_JAKRKC020000002
VERSION     NZ_JAKRKC020000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura luzonensis
  ORGANISM  Actinomadura luzonensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Genome draft of Actinomadura sp. ATCC 31491
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Genome draft of Actinomadura sp. ATCC 31491
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
REFERENCE   4  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
REFERENCE   5  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
REFERENCE   6  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. v1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 89.6x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022664455.2-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:46:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,232
            CDSs (total)                      :: 10,155
            Genes (coding)                    :: 10,004
            CDSs (with protein)               :: 10,004
            Genes (RNA)                       :: 77
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 36 of 151
            Pseudo Genes (incomplete)         :: 126 of 151
            Pseudo Genes (internal stop)      :: 3 of 151
            Pseudo Genes (multiple problems)  :: 14 of 151
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2474157
            Orig. end                         :: 2497798
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAKRKC020000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23641
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23641
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23641
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13641](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13641
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    82..95
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.49"
                     /tool="antismash"
     misc_feature    complement(83..100)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.34"
                     /tool="antismash"
     misc_feature    86..99
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.33"
                     /tool="antismash"
     misc_feature    87..100
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.01"
                     /tool="antismash"
     misc_feature    89..102
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.2"
                     /tool="antismash"
     misc_feature    89..105
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.51"
                     /tool="antismash"
     misc_feature    complement(95..104)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.18"
                     /tool="antismash"
     gene            142..834
                     /locus_tag="MF672_RS41845"
                     /old_locus_tag="MF672_041845"
     CDS             142..834
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017604734.1"
                     /locus_tag="MF672_RS41845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041845"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_242381897.1"
                     /transl_table=11
                     /translation="MRGLHGSVLDELGLLITSAAVPPGHVLRIEELEARFRVSRTVVRE
                     AVRVLESMGLVRSRRRVGVIVAPREAWHVFDPRVIRWRLDGEGRLAQLRSLSELRRGVE
                     PAAAALAAARATPAQCGELAGAVMRMAAHGRAGDLESYLAADVGFHRTLLEASGNEMMA
                     ALAGVVAEVLRGRTRHHLMPDRPDPAAIRLHAEVAEAVQGGDGPAAERAMRAIVDEAAH
                     AMLTGRPA"
     gene            complement(849..1709)
                     /locus_tag="MF672_RS41850"
                     /old_locus_tag="MF672_041850"
     CDS             complement(849..1709)
                     /NRPS_PKS="Domain: Abhydrolase_1 (26-268). E-value:
                     1.2e-29. Score: 95.6. Matches aSDomain:
                     nrpspksdomains_MF672_RS41850_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546027.1"
                     /locus_tag="MF672_RS41850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041850"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_242381898.1"
                     /sec_met_domain="PF00561 (E-value: 4.8e-26, bitscore: 89.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-18, bitscore:
                     65.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDDFATDVIDVGETELFVRHGGSGAPLLLLHGHPRTHATWHRVA
                     PLLAPHYYVVCPDLRGYGRSGKPPTTPDHAPYGKRAMARDMVALMRALGHDRFAVAGHD
                     RGAYVAHRLAADHPGAVSRLVIMDAVPIGEALARADARFAASWWHWFFFGQTDKPAERV
                     INADPDAWYQATAEQMGEEAYEDYRRAIHDPDTVHGMCEDYRAGLTVDRAADDADRAAG
                     RRVTCPTLFLWSSKDDMEELYGDPLAIWRTWADDVTGHPIDSGHHVAEEAPEELAASLL
                     GFLRP"
     aSDomain        complement(906..1631)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MF672_RS41850_Abhydrolase_1.1"
                     /evalue="1.20E-29"
                     /label="MF672_RS41850_Abhydrolase_1.1"
                     /locus_tag="MF672_RS41850"
                     /protein_end="268"
                     /protein_start="26"
                     /score="95.6"
                     /tool="antismash"
                     /translation="PLLLLHGHPRTHATWHRVAPLLAPHYYVVCPDLRGYGRSGKPPTT
                     PDHAPYGKRAMARDMVALMRALGHDRFAVAGHDRGAYVAHRLAADHPGAVSRLVIMDAV
                     PIGEALARADARFAASWWHWFFFGQTDKPAERVINADPDAWYQATAEQMGEEAYEDYRR
                     AIHDPDTVHGMCEDYRAGLTVDRAADDADRAAGRRVTCPTLFLWSSKDDMEELYGDPLA
                     IWRTWADDVTGHPIDSGHHV"
     gene            complement(1766..2359)
                     /locus_tag="MF672_RS41855"
                     /old_locus_tag="MF672_041855"
     CDS             complement(1766..2359)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546028.1"
                     /locus_tag="MF672_RS41855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041855"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_242381899.1"
                     /transl_table=11
                     /translation="MGYAASEPGTTAVASALAIKILIAGGFGVGKTTMVGTISEIRPLH
                     TEELLSERGVGVDDLSGVESKTTTTVALDFGRITIRDGLWLYLFGTPGQDRFWFMWDEL
                     ALGALGAVVLADTRRLQDCFPAVDYFEQRGIPFVVAVNCFDGARRYEPVKVRRALGLSA
                     TTPIVLCDVRRRESVKEVLTTLVTYAVKGLQPPG"
     gene            complement(2340..2690)
                     /locus_tag="MF672_RS41860"
                     /old_locus_tag="MF672_041860"
     CDS             complement(2340..2690)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017170.5"
                     /locus_tag="MF672_RS41860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041860"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_242381900.1"
                     /transl_table=11
                     /translation="MTGEDPGPLIRLYGLTGGRARPQGETFDLVAIVTTAAGSHEFADL
                     LPEHRAVLSLCRRPTPVADVAAHLRLPLNITRVILGDLRREGLVGIERPRPAAQTIDER
                     IYREVLHGLRSL"
     gene            complement(2687..3112)
                     /locus_tag="MF672_RS41865"
                     /old_locus_tag="MF672_041865"
     CDS             complement(2687..3112)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546030.1"
                     /locus_tag="MF672_RS41865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041865"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_020546030.1"
                     /transl_table=11
                     /translation="MPDPRSELSWLLDDLTQRVPGIRHAIVLSADGLAMGGSRDLTRED
                     AEHLSAISAGSHSLAMGAGRHFGLGGVRQTIIEMEGGFLFVTAAGQGARLAVLAAADAE
                     LGMVTYEMALMVKRVGEHLSAQPRGAAPAPAWNGARP"
     gene            complement(3093..5522)
                     /locus_tag="MF672_RS41870"
                     /old_locus_tag="MF672_041870"
     CDS             complement(3093..5522)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019974.5"
                     /locus_tag="MF672_RS41870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041870"
                     /product="nitrate- and nitrite sensing domain-containing
                     protein"
                     /protein_id="WP_242381901.1"
                     /transl_table=11
                     /translation="MSSPPPIRAKLLRILLLPLVSMAALWGFIAYSSVQEISDVSQTQD
                     RWEAIGSPVLQLIIELQRERQLSAEAPRSTGSYAPLLDQRRNTDVKVDRLREVIGTVDA
                     GEEAPAQVRALVQALDGLQSLRASADGGVLAPPLTIIEAYNNLIAVANRQFTDRDALSD
                     VSSFRSVRGMAAYVATAEYLGREHAVLTATIVQRRMSPTDRAAFVAAMSSRRLVFANAE
                     RDAGPELKADYDELVASLHYRRVVEVEDELFTFDTGGPPPVEGAQWKGDAEALLGAINR
                     DTQAELARAAEEAESQKSGAYWRVGIVLLLGLAAMLVSLALSYRFGRSLIEELRRLQAS
                     AVELAEERLPRLVERLRRGDDVDPATEAPGLDPADTAEVDRVVDAFSAVRRTAVEAAVG
                     QAALRKGVGQVFLNLARRNQALLHRQLALLDTMERRVDEPEVLEDLFKLDHLTTRMRRH
                     AENLIILSDAVPARRWRDPVQLFDVVRAAVLEVEDYTRVTVAPMPQAPMLVGAAVTDVI
                     HLVAELVENATVFSPPDTSVQIRGMTAANGFALEVEDRGLGLNQDTLDQLNARLADPPE
                     FDLDDSDRLGLFVVSRLAARHGIKISLRRSPYDGTTAIVLLPGALLAGTDEPARPAEPV
                     SAGRPVRALDTGHGEPAPPAAPEPRAPLDATLLNTVLDPVPDPVLDGGTIVNGHAARPG
                     DARPEEPVRPERGTWFDAAVPPGPPAGWSVTVPPQEADDDLDGLPMRVPQASLAPQLRT
                     ATRGRNPGISVRTPEELAQLMSSMQQGWQQGRRQADERGQDVWNRKDDHPDARPQK"
     misc_feature    complement(5475..5477)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5857..6321
                     /locus_tag="MF672_RS41875"
                     /old_locus_tag="MF672_041875"
     CDS             5857..6321
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS41875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_041875"
                     /product="hypothetical protein"
                     /protein_id="WP_242381902.1"
                     /transl_table=11
                     /translation="MSSNSTRRGRRLALAGVGLGAALSAALALVPSAASGATITQMAAQ
                     GSIVRGSVACSGPFAAEDGDIVAGSGTSFTLNSLNVPIPVAADWELRRADPLNDFFTDG
                     EVLQSQHTDFFTATVQTPSKLVPGNFWVCVSTTSRTPVQYKAFVGNGVPA"
     gene            complement(6328..7500)
                     /locus_tag="MF672_RS41880"
                     /old_locus_tag="MF672_041880"
     CDS             complement(6328..7500)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009083486.1"
                     /locus_tag="MF672_RS41880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041880"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_242381903.1"
                     /transl_table=11
                     /translation="MNERTVLISGAGVGGPALAYWLARHNFRVTVVERAGALRSSGNPV
                     DVRGPAMDVAARMGIVPRLREAATGNTGLAFVDAAGRRLARVDMPGGRRGEEIELPRGD
                     LAAILYDAAREHAEFLFDDSMTAIAQDAHGVEVTFERAAPRRFDLVIGTDGLHSATRRL
                     AFGEEGGLVRHMGLYVATTPLGGHRARERHEGGDVVMHNAPGRAVAVSPTPAGDLAFFL
                     YRAPAEPGFDHRDAEQHKRMLAAAFAGVGWRAPELLERVRAATDLYFDSVSQVRLPRWW
                     TGRVALLGDAASCVSLFGDGSTLAMAGAYTLAAELAATPADPQAAFARYESAHRRLVDP
                     KQANVGRAAALMVPATRAGVATRNLAARAWPLASAVARLRRVPAGRPTPA"
     misc_feature    7516..7534
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.91"
                     /tool="antismash"
     gene            7577..8227
                     /locus_tag="MF672_RS41885"
                     /old_locus_tag="MF672_041885"
     CDS             7577..8227
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF044515.2"
                     /locus_tag="MF672_RS41885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041885"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_242381904.1"
                     /transl_table=11
                     /translation="MDGKTQGLRADARRNRDLILAAAQELFLEQGVDVALEEVARRAGV
                     GIGTLYRRFPDREALLRGVGEAGLRRMAELAEAARREEPDAWHALCRFLRCCTELRLGE
                     LSAKLDPVLHQRMRAGEEQHELRERVTEGLLGMIAEAQADGALRADVGPVDLALIMTLH
                     VYAPPGLPGGQGLPRVVEIVLDGLRADRATPLPGPRSTSADLRRYTAVEPGAR"
     gene            complement(8265..8804)
                     /locus_tag="MF672_RS41890"
                     /old_locus_tag="MF672_041890"
     CDS             complement(8265..8804)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546032.1"
                     /locus_tag="MF672_RS41890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041890"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_242381905.1"
                     /transl_table=11
                     /translation="MGNTSASSHQRPTGRTDEETLSDSYRAHAPALRSYLRRFISPQDV
                     EDLLQVVFADAWRSRGRYDPGRSQAAWLYVIAHRRAVDHLRVRRLATVPLDAVAEAAAP
                     AQRPADEEVADRDRVRRALAALSHAQRQVIELAYYGELTQQEIAERLRVPLGTVKARTS
                     RGLHKLSALLSAAEAA"
     misc_feature    8834..8849
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     misc_feature    complement(8835..8844)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.02"
                     /tool="antismash"
     gene            complement(8897..9850)
                     /locus_tag="MF672_RS41895"
                     /old_locus_tag="MF672_041895"
     CDS             complement(8897..9850)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888349.1"
                     /locus_tag="MF672_RS41895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041895"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_242381906.1"
                     /transl_table=11
                     /translation="MSEEEAGYGIGAVSRLLGVPAPTLRTWNLRYGLGPSRRSAGGHRR
                     YDSGDLDRLREMQRLIAEGLPPSEAARRARRARTATPPAGSPAAAAPGSTTPASTTPAT
                     TATASTATASTATGGATALVRAAYALDSHAVTALLDAALAAEGVRSTWERLVLPAFDAV
                     CRRQDGTGAGIDVEHLLSDRLLAALHGHALRQAPGPRGRRPVLLACAEEEQHTLPVHAL
                     SAALAEEGVETRLLGARTPYAALAHAMRRLHPAAVFLWSQQESTGDTAPLAGLPRLRPA
                     ARLVLGGRGWPETLPAGVIRVDTFREALSQIRRTLP"
     misc_feature    9978..9998
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            10001..11257
                     /locus_tag="MF672_RS41900"
                     /old_locus_tag="MF672_041900"
     CDS             10001..11257
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.5"
                     /locus_tag="MF672_RS41900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041900"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_247815699.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-37, bitscore:
                     126.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVTPPARTRTGGPQIGSPQTSTEMSRVRELVERRLDDLLDQEL
                     ARLGFLGAEGVGLVRRHLAAFARDGGKRLRPAFVYWGHRAAGGTGEHLEPVLNAACAVE
                     LVHVAALLLDDVMDEAAERRGRPAAHVALAAEHRRAGLRGEPGRYGESQASLLALLALA
                     WADAALLGAGPHLADALDVLTRLRVEVTAGQQLDLAATAAGGADTARTRTIALYKSAKY
                     TIERPLHLGHAVAGGDPAARRALSAYALPLGEAFQLRDDVLGVFGDPGRTGKPAGDLRQ
                     GKPNHLVAVARERSGPSGAALLDAVAAARDDDRTAAARGDDRTAAARGDDRTAAARDDD
                     RTATARGDGGTAAAGDDGGLVAAARELIVSCGALELAERRIAALAEEADAALGQVPGLP
                     ADARRALTELTVLATDRSR"
     gene            11257..12717
                     /locus_tag="MF672_RS41905"
                     /old_locus_tag="MF672_041905"
     CDS             11257..12717
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546035.1"
                     /locus_tag="MF672_RS41905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041905"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_242384097.1"
                     /sec_met_domain="DAO (E-value: 3.6e-13, bitscore: 47.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGTGPVVVIGAGLAGLAAAVRLAAAGREVTVVEARDEPGGCCGT
                     ARLGPYRFDTGPSVLTMPGALADTFGAAGEELRDWLPLRRLDPAYRLAFHDGTHLDVTP
                     DGEAMAERVRELCGPAEAARYLRYRRLLGELFAVEWPAFIDADMTRLGSLARPLALARL
                     AALGGFRRLDRLAARHLSDERLIKAHTFQSLYVGLSPQRALGIYAVIAHMDTVGGVYFP
                     ERGGMHAVPSALAALLEKLGAPVRYGVRAARVETGAGGVTGVLLEDGERLPAGHVVVAC
                     DRYAARRLLPGRAADWRMRRPRHSPSCLVLHAGLDRPPAGQAHHTLHFGGQWRETFAAL
                     EAGRPQPDPSLLVTCPAGDGEAAPPGHVTLSVLEPAPNLESADWDRLRPRLEERLLARL
                     AALGYGDLSAAPRLVLDPPAWAALGHTAGTPFALDHRFTQTAWLRPSGVARRVPGLHFA
                     GMHTAPGVGVPPVLISGRLAAERILTSR"
     gene            12742..13641
                     /locus_tag="MF672_RS41910"
                     /old_locus_tag="MF672_041910"
     CDS             12742..13641
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890490.1"
                     /locus_tag="MF672_RS41910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041910"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_242384098.1"
                     /sec_met_domain="phytoene_synt (E-value: 9.7e-93, bitscore:
                     307.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.4e-65,
                     bitscore: 218.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTASYERCRRLHARYGRSYYLATLLLPAWKRRHVHALYGFARY
                     ADEIVDSFTMSADRRAALDDLCDRTARGLAGEPVADPVLPAFLHTVRSFGITRADVDSF
                     LAAMRADLSVTGYATYDDLLGYMEGSAAVIGTMMLPVLEALPGEERAAREPARQLGLAF
                     QLTNFLRDVAEDHARGRVYLPAQDLAAFGVEPADLGRPRTGRAVRELLAFEARRAREHY
                     RAAAPGIDLLVASSRPCVRAAVELYGGILVEIERGGFAVLERRVRVPRRRKAAAFARHL
                     LASAEAGRHERRVRVELP"
     gene            13638..14738
                     /locus_tag="MF672_RS41915"
                     /old_locus_tag="MF672_041915"
     CDS             13638..14738
                     /EC_number="2.3.1.274"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /GO_function="GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014554.5"
                     /locus_tag="MF672_RS41915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041915"
                     /product="phosphate acyltransferase"
                     /protein_id="WP_247815700.1"
                     /transl_table=11
                     /translation="MTPANGRGPATGGRDSATGGRDSATGGRDSATGGRDSGAATGGRG
                     PAAGRWCWTPWAGTTARPRWWRGRWRRGARTACRSSWSAASRTWPASWPPATPPSELPI
                     VHAPDAVPMAERGAGGPALPGSSLAVGCGLLARGEGAAFVSAGSTGAVVSQAVRLVGRA
                     EGVLRPALAIALPALSGGASVLVDAGATADPTPEMMAQFALLGAGYARAVLGVPDPVAG
                     LLSIGSEPGKGNRLARRAEELLRRQPARFHGNIEGHDVLSGAVDVIVTDGFTGNVVLKN
                     VEGCVRTALTMVAQAGLADPAALAGVARRYDPQTHGGAALLGLRGTVVVAHGSSRAATI
                     ARACVVAHALSGVRVDAGLAAAPEPA"
     gene            complement(14753..15457)
                     /locus_tag="MF672_RS41920"
                     /old_locus_tag="MF672_041920"
     CDS             complement(14753..15457)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546037.1"
                     /locus_tag="MF672_RS41920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041920"
                     /product="spheroidene monooxygenase"
                     /protein_id="WP_242384059.1"
                     /transl_table=11
                     /translation="MTDSTAAPIASFHLIRYGSVDAMRHMAFDRPLLRGTAGLTFWRLL
                     GTGRGRSMSLGADLRRWALFAVWREEADLEAFLRASPVAARWRAEADERWQVRLAPLSA
                     RGTWGGRSPFGRLAGGRRDGGGPVAVLTRASIRARRLAAFYRSVPPVDRLLARQDGCLA
                     SVGVGEWPLARQATFSLWRDAAAMRRFAYGDDAHLRVVDRVRRDGWYSEELFARFVPYG
                     SEGTWNGADPLG"
     misc_feature    15420..15433
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.61"
                     /tool="antismash"
     gene            15432..16028
                     /locus_tag="MF672_RS41925"
                     /old_locus_tag="MF672_041925"
     CDS             15432..16028
                     /EC_number="2.3.1.275"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0043772 - acyl-phosphate
                     glycerol-3-phosphate acyltransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546038.1"
                     /locus_tag="MF672_RS41925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041925"
                     /product="glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_242384060.1"
                     /transl_table=11
                     /translation="MGAAVLSVIVGYLLGSIPVAVLLARGHGFDPRAVGDRNPGFWNVK
                     EQLGWRSAVPVFAGDTLKGTLAALAALLLSGGHTTGPGVVAGDSVVPVYLAVAAAMAGH
                     AWPVFAGFRGGRSILTFAGGVAVICPPAFALAVAALVAVALGARSFAVGARVAVFGVPA
                     LQLLFAPAEVVAGTGALMCLIGLRFGQAALSSRRS"
     gene            complement(15979..17202)
                     /locus_tag="MF672_RS41930"
                     /old_locus_tag="MF672_041930"
     CDS             complement(15979..17202)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890494.1"
                     /locus_tag="MF672_RS41930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041930"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_247815701.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.6e-20,
                     bitscore: 68.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRLAGTARAGGRLLGAAQAVAAGVVLARLARGRRRLPPLRAAA
                     APGALISVVVPARDEAARIGPCLRAALKDPAVAEVIVVDDRSTDGTGPLAAALGATVVT
                     GEPLPPGWVGKQWALRQGVAAARGDVVVTLDADTRPEPGLFGALARALDGRDLVSAAPR
                     FACDGPLEQALHASMLATLVYRFGPVGRADPLPPHRVLANGQCLAFRRDAMTEIDGFAA
                     VRGHMTDDVALARFLAGRGWRIGFLDGGGLLEVDMHDSTAELWREWGRSLPLRDVTGAG
                     WRAADLAVVWLTAALPALRLAAGRPSRLDLALLGVRLLLTGALRGSYTRPGAALLLSPL
                     LDPAAAVRLTQATLRPVRRWRGRTYPANPANPANPADPANPAAQAAPADPAVSSGGTTA
                     RPGRNAAR"
     gene            complement(17199..18650)
                     /locus_tag="MF672_RS41935"
                     /old_locus_tag="MF672_041935"
     CDS             complement(17199..18650)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546040.1"
                     /locus_tag="MF672_RS41935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041935"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_242381977.1"
                     /transl_table=11
                     /translation="MTDVIVVGGGVGGMASALLLAGQGHRVRLYERLPRLGGKLAEHRR
                     DGFSFSEGPSLLTMPGLFRDLGLRRAFVEPAELCRYRFADGSVLTARRDPERMAAEVDR
                     LAPGEGAAWRAFHAWAEGCLRAAGRTFFAGPLGRPPRAARLGDLLAVAPAATLDGLARR
                     FFRDPRLRQYVGRYATYAGSSPYRAPAALGCVPALEHGEGGWYVPGGLPRLAEDLAGLL
                     KEAGVLVHLSAPVEAVTARGGEVTGVRLAGGGHERAGVVVAGVDAAALYGRLLPDRRRL
                     RRLAGLGLSSSAFLLMAGVEGRTPGLAHHTVVFSGDYEREFADIFDRREPPDDPTIYVG
                     CSAVDDPGQAPAGTENWTMLVNVPARDPGRWRIGVDAYRDLVLERLAGRGLDLAGRLRF
                     VDVLTPADLRDRYGAWAGAIYGSAYRGRLAPFLRPGNRGPRRGLYLVGGSVHPGGGLPM
                     VTLGARIVAGLVREDFGDPREAALR"
     gene            complement(18691..19485)
                     /locus_tag="MF672_RS41940"
                     /old_locus_tag="MF672_041940"
     CDS             complement(18691..19485)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546041.1"
                     /locus_tag="MF672_RS41940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_041940"
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_242381978.1"
                     /transl_table=11
                     /translation="MGETRSAPVTAVPAAAGTARAVGLTALVVMVACQVLSGISPEPVR
                     YTGIVVAVLAVSVLGFTAAAWGARRAAAGFAAAVLAGYAAEAVGLRTGFPFGHYRYTDL
                     LWPQLGGVPAVVALAWGGMGLAAYAVAAAITTGRARPAVGALALTAWDLFLDPQMVGLG
                     LWTWAEPGPYRGIPLSNYAGWLLVSALVMLLLRRIAGDAPARGAVGVYTTMAVMETVGF
                     AAVFQPPDPLVAAAGGISMGVFAALAWRRLWQKGNGWRPWQR"
     misc_feature    19579..19593
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.41"
                     /tool="antismash"
     misc_feature    19772..19787
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.03"
                     /tool="antismash"
     misc_feature    complement(20661..20675)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     misc_feature    21579..21594
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    complement(21927..21941)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(22106..22119)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    22914..22928
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.01"
                     /tool="antismash"
ORIGIN
        1 gacgcccatc acgacgacga gcgggggagc cggcgcgctg ttcggaggtt ccgcgtggag
       61 catggttaag tatccttaat acgtaactat tacataataa atcatacttt tgtccgtttt
      121 ggcgctcggg gtgggtcgat catgcggggt ctgcacggca gcgttctcga cgagctgggc
      181 ctgctgatca cctcggccgc cgtcccgccc ggccacgtgc tccgcatcga ggagctggag
      241 gcccgcttcc gcgtctcgcg caccgtcgtc agggaggccg tccgcgtcct ggagtcgatg
      301 ggcctggtac ggagccggcg gcgggtcggg gtcatcgtcg cgccgcgcga ggcctggcac
      361 gtgttcgacc cgcgggtgat ccggtggcgg ctcgacggcg agggccgcct ggcgcagctc
      421 cgctcgctca gcgagctgcg ccgcggcgtc gagcccgccg cggccgcgct ggccgccgcc
      481 cgcgccacgc ccgcgcagtg cggcgagctg gcgggcgccg tcatgcggat ggccgcccac
      541 gggcgcgccg gcgacctgga gagctacctc gccgccgacg tcggcttcca ccgcacgctg
      601 ctggaggcga gcggcaacga gatgatggcg gcgctcgccg gcgtggtggc cgaggtgctg
      661 cgcgggcgca cccgccacca cctgatgccc gaccggcccg acccggccgc gatccgcctg
      721 cacgccgagg tcgccgaggc cgtgcagggc ggcgacgggc cggcggccga gcgggccatg
      781 cgcgcgatcg tggacgaggc cgcccacgcc atgctcaccg gccggcccgc ctgaccgccc
      841 cctcggcgtc atggccgcag gaagcccagc agggatgccg ccagctcctc cggagcctcc
      901 tcggcgacgt ggtggccgct gtcgatcggg tggccggtca cgtcgtcggc ccaggtgcgc
      961 cagatggcca gcgggtcgcc gtacagctcc tccatgtcgt ccttcgagga ccacaggaac
     1021 agcgtggggc aggtgacgcg gcggcccgcg gcccggtcgg cgtcgtcggc ggcgcggtcc
     1081 accgtgaggc cggcgcggta gtcctcgcac atgccgtgga ccgtgtccgg gtcgtggatg
     1141 gcgcggcggt agtcctcgta cgcctcctcg cccatctgct cggcggtggc ctggtaccag
     1201 gcgtccgggt cggcgttgat gacccgttcg gcgggtttgt cggtctggcc gaagaagaac
     1261 cagtgccacc aggacgccgc gaaacgcgcg tcggcgcggg ccagcgcctc gccgatgggc
     1321 accgcgtcca tgatgaccag ccgcgacacc gcgccggggt ggtcggcggc gagacggtgg
     1381 gccacgtacg cgccccggtc gtgcccggcc accgcgaagc ggtcgtggcc gagcgcgcgc
     1441 atcagcgcca ccatgtcgcg ggccatggcg cgcttgccgt agggggcgtg gtcgggggtc
     1501 gtgggcggct tgccggaacg gccgtagccg cgcaggtcgg ggcagaccac gtagtaatgg
     1561 ggagcgagga ggggggcgac ccggtgccag gtcgcgtgcg tacgggggtg gccgtggagg
     1621 agcagcagcg gggcgccgga gccgccgtgc cggacgaaca gctccgtctc gcccacgtcg
     1681 atcacatcgg tcgcgaagtc gtcgaacatc cgcggcctct acccaccagg acgggaaccg
     1741 ggcgggcccc gcgcgggaaa gccgatcacc ccggcggctg cagccccttc accgcgtacg
     1801 tgacgagtgt cgtcagcacc tccttgaccg actcgcgccg ccgcacgtcg cacagcacga
     1861 tcggggtcgt cgcgctgagg ccgagggccc gccgcacctt gaccggctcg taccggcgcg
     1921 ccccgtcgaa gcagttgacc gccaccacga acgggatgcc gcgctgctcg aagtagtcga
     1981 ccgcggggaa gcagtcctgg aggcggcgcg tgtcggccag caccacggcc ccgagcgcgc
     2041 cgagggccag ctcgtcccac atgaaccaga accggtcctg ccccggcgtg ccgaacaggt
     2101 acagccacag cccgtcgcgg atggtgatgc ggccgaagtc cagcgcgacg gtggtggtgg
     2161 tcttggactc cacgcccgac aggtcgtcca ccccgacgcc gcgctcgctc agcagctcct
     2221 cggtgtgcag ggggcggatc tcgctgatcg tgccgaccat ggtggtcttg ccgacgccga
     2281 aaccgcccgc gatgaggatc ttgatggcca gggccgaggc gacggccgtc gtccccggct
     2341 cagaggctgc gtagcccatg cagcacttcc ctgtagatgc gttcgtcgat cgtctgcgcc
     2401 gcggggcggg ggcgttcgat gccgaccagg ccctcgcgcc gcaggtcgcc caggatgacc
     2461 cgggtgatgt tcagcggcag cctgaggtgc gccgcgacgt cggccaccgg ggtcggccgg
     2521 cggcacagcg acagcacggc gcggtgctcg gggagcaggt ccgcgaactc gtgcgaaccc
     2581 gcggccgtcg tcacgatggc caccaggtcg aacgtctcgc cctgcgggcg cgcccggccc
     2641 ccggtcagcc cgtacaggcg gatcaggggg ccggggtcct caccggtcac ggtctcgcgc
     2701 cgttccaggc gggtgccggt gccgctcccc tcggctgcgc ggagaggtgc tcgccgaccc
     2761 tcttgaccat cagcgccatc tcgtaggtga ccatgcccag ctcggcgtcg gccgccgcga
     2821 gcaccgccag ccgggctccc tggcccgccg cggtgacgaa caggaagccc ccttccatct
     2881 cgatgatcgt ctgccgtacg ccgcccaggc cgaaatgccg gcccgcgccc atcgcgaggc
     2941 tgtgactgcc ggcggagatg gcggacaggt gctcggcgtc ctcgcgggtc aggtcacgcg
     3001 agccgcccat ggcgagcccg tcggcggaca gcacgatggc gtgccggatg ccggggacgc
     3061 gctgggtcag gtcgtcgagg agccagctca gttcacttct ggggtcgggc atcgggatgg
     3121 tcgtcctttc ggttccacac gtcctgtccg cgctcgtcgg cctggcggcg tccttgctgc
     3181 cagccctgct gcatggagga catgagttgt gcgagctcct ccggcgtacg cacggagatg
     3241 ccgggattcc ggccgcgcgt ggcggtgcgg agctgagggg cgaggctggc ctgtggcacc
     3301 cgcatgggca ggccgtcgag gtcgtcgtcg gcctcctgcg ggggcacggt gacgctccag
     3361 ccggcgggcg ggccgggggg gacggcggcg tcgaaccagg tcccgcgttc gggcctgacc
     3421 ggctcctccg gccgcgcgtc ccccggccgg gccgcgtggc cgttgacgat cgtgccaccg
     3481 tcgaggacgg ggtcgggcac ggggtcgagg acggtgttca ggagggtggc gtcgagcggc
     3541 gcgcggggct ccggcgcggc gggcggcgcc ggctcgccgt ggccggtgtc gagcgcgcgc
     3601 accggccggc ccgcgctgac gggctcggcg ggccgggccg gctcgtccgt cccggccagc
     3661 agcgcgccgg gcagcagcac gatcgcggtg gtcccgtcgt acggcgaccg ccgcagcgag
     3721 atcttgatcc cgtgccgcgc cgccagccgg gacaccacga acagcccgag ccggtcgctg
     3781 tcgtccaggt cgaactccgg ggggtcggcg aggcgggcgt tgagctggtc cagggtgtcc
     3841 tggttgagcc cgagcccgcg gtcctccacc tccagggcga agccgttggc cgccgtcatg
     3901 ccgcggatct gcacggaggt gtcgggcggc gagaagacgg tggcgttctc caccagctcg
     3961 gccaccaggt ggatgacgtc ggtgaccgcc gccccgacca gcatcggggc ctgcggcatc
     4021 ggcgcgaccg tgacccgggt gtagtcctcg acctccagca ccgccgcccg tacgacgtcg
     4081 aagagctgga ccgggtcgcg ccagcggcgc gccgggaccg cgtcggacag gatgatgagg
     4141 ttctccgcgt gccgccgcat gcgggtggtg aggtggtcga gcttgaacag gtcctccagc
     4201 acctcgggct cgtccaccct gcgctccatc gtgtcgagca gcgcgagctg ccggtgcagc
     4261 agcgcctggt tgcgccgcgc caggttgagg aacacctggc cgacgccctt gcgcagggcc
     4321 gcctgcccga ccgcggcctc gaccgcggtg cggcgcaccg ccgagaaggc gtccaccacg
     4381 cggtcgacct cggcggtgtc ggccgggtcc aggccggggg cctcggtggc cgggtccacg
     4441 tcgtcgccgc ggcgcagccg ttccaccagg cggggcagcc gctcctcggc cagctccacc
     4501 gccgacgcct gcagccgccg cagctcctcg atgagcgagc ggccgaagcg gtaggacagc
     4561 gccagcgaca ccagcatcgc ggcgagcccg aggagcagga cgatcccgac ccgccagtac
     4621 gcgccgctct tctggctctc cgcctcctcg gcggccctgg ccagctcggc ctgggtgtcc
     4681 cggttgatgg cgccgagcag cgcctcggcg tcgcccttcc actgggcgcc ctcgacgggc
     4741 ggcggcccgc cggtgtcgaa ggtgaacagc tcgtcctcga cctcgaccac ccgccggtag
     4801 tgcaggctgg ccaccagctc gtcgtagtcg gccttcagct cggggccggc gtcgcgctcg
     4861 gcgttggcga agaccagccg gcggctgctc atcgcggcca cgaacgcggc ccggtcggtg
     4921 ggcgacatcc gccgctgcac gatggtggcg gtgagcaccg cgtgctcgcg gcccaggtac
     4981 tcggcggtgg cgacgtaggc cgccatgccg cgcaccgagc ggaaggagga gacgtcgctc
     5041 agcgcgtcgc ggtcggtgaa ctgccggttg gccaccgcga tgaggttgtt gtacgcctcg
     5101 atgatggtca gcggcggggc cagcacgccg ccgtcggccg aggcgcgcag cgactgcagc
     5161 ccgtcgaggg cctgcaccag ggcgcgcacc tgggcggggg cctcctcgcc cgcgtcgacg
     5221 gtgccgatga cctcgcgcag ccggtccacc ttgacgtcgg tgttgcggcg ctggtccagg
     5281 aggggcgcgt acgacccggt gctgcgcggg gcctcggccg agagctgccg ctcgcgctgc
     5341 agctcgatga tgagctgcag caccggcgag ccgatggcct cccagcggtc ctgggtctgc
     5401 gagacgtcgc tgatctcctg gacgctggag tacgcgatga agccccacag ggccgccatc
     5461 gacaccagcg ggagtaacag gatccggagc agtttggcac ggatcggagg gggcgagctc
     5521 atacgatcat gtccaattcc gccgggcagc cgcgagccgg taccgccccc cgtggatgcc
     5581 cgtcacgact gattgcgcct tacaggtccg tccactatgc cgacggggca gatgtacttc
     5641 aaggtacgga tgcgaagaaa cctcgcgaat gacgggttga ctctttgtca acacaccgat
     5701 cgtgttcgta acggttggcg cgtcacccaa agttacggat caagcccgtt tctcgaacat
     5761 tgttccgtgc catggaacgt cctggaaccg gtcggcacgc ctccccggca gaggcgccgg
     5821 gcatcggaac cggcgcccgg atccgaggag agactcttgt ccagcaacag cactcgcagg
     5881 ggccgccgtc tcgcgctcgc cggggtggga ctcggcgccg ccctctccgc cgccctcgcc
     5941 ctcgtgccgt ccgccgccag cggcgccacg atcacccaga tggccgccca gggcagcatc
     6001 gtgcgcggct cggtcgcgtg ctcaggcccg ttcgcggccg aggacggcga catcgtcgcg
     6061 ggcagcggca cgtccttcac cctcaactcg ctcaacgtgc cgatccccgt ggcggcggac
     6121 tgggagctgc ggcgggccga cccgctcaac gacttcttca ccgacggcga ggtcctccag
     6181 tcgcagcaca ccgacttctt caccgccacc gtgcagacgc ccagcaagct ggtgccgggc
     6241 aacttctggg tgtgcgtgag caccacgtcg cgcacccccg tgcagtacaa ggcgttcgtg
     6301 ggcaacggcg tcccggcctg agccggatca ggccggcgtg gggcggccgg cggggacgcg
     6361 gcgcaggcgg gccacggccg aggcgagcgg ccaggcccgg gccgccaggt tgcgcgtcgc
     6421 gaccccggcc cgggtcgcgg gcaccatgag ggcggccgcg cggccgacgt tcgcctgctt
     6481 ggggtcgacc aggcggcggt gcgcgctctc gtagcgggcg aaggccgcct gcgggtcggc
     6541 gggcgtggcg gccagctccg ccgccagcgt gtacgccccc gccatggcca gcgtggagcc
     6601 gtccccgaac agcgacacgc acgaggcggc gtcaccgagc agcgccaccc ggccggtcca
     6661 ccagcgcggc agccgcacct ggctgaccga gtcgaagtag aggtcggtgg cggcccgcac
     6721 ccgctccagc agctccggcg cccgccagcc cacccccgcg aacgccgcgg ccagcatccg
     6781 cttgtgctgc tcggcgtcgc ggtggtcgaa gccgggctcg gccggggcgc ggtagaggaa
     6841 gaaggcgagg tcgccggcgg gcgtggggct caccgcgacg gcccggccgg gcgcgttgtg
     6901 catgacgacg tccccgccct cgtgcctctc cctggcgcgg tggccgccga gcggggtggt
     6961 ggcgacgtac aggcccatgt gccgcaccag gccgccctcc tcgccgaacg ccagccggcg
     7021 cgtcgcggag tgcaggccgt cggtgccgat caccaggtcg aagcggcggg gcgcggcccg
     7081 ctcgaaggtc acctcgacgc cgtgcgcgtc ctgcgcgatc gccgtcatgc tgtcgtcgaa
     7141 caggaactcg gcgtgctcgc gggccgcgtc gtacaggatc gcggcgaggt cgccgcgcgg
     7201 cagctcgatc tcctcgccgc gccgcccgcc gggcatgtcc acgcgggcca ggcggcggcc
     7261 cgccgcgtcg acgaaggcga ggccggtgtt gccggtggcc gcctcgcgca gccgggggac
     7321 gatgcccatg cgggcggcga cgtccatggc ggggccgcgc acgtccaccg ggttgccgct
     7381 ggagcgcagc gctccggcgc gctcgacgac cgtcacccgg aagttgtgcc gggccagcca
     7441 gtaggcgagg gccgggccgc ccacgcccgc tccggagatc agcactgtgc gctcgttcat
     7501 gtccaccact ccgctaactg gatgaatttc ctccgcttgt ttgcgacggt acctcaagtg
     7561 gaggaaaatc gtccagatgg atgggaaaac gcaggggctc cgcgcggacg cccgccgcaa
     7621 ccgggacctg atcctcgccg ccgcccagga gctgttcctg gagcagggcg tcgacgtggc
     7681 gctggaggag gtggccaggc gcgcgggcgt cggcatcggc acgctctacc ggcgcttccc
     7741 cgaccgggag gcgctgctgc gcggcgtcgg cgaggcgggc ctgcggcgca tggccgagct
     7801 ggccgaggcc gcccggcgcg aggagcccga cgcctggcac gcgctctgcc ggttcctgcg
     7861 gtgctgcacg gagctgcgcc tcggggagct gtcggccaag ctcgaccccg tcctgcacca
     7921 gcggatgcgc gccggcgagg agcagcacga gctgcgcgag cgggtgaccg aggggctgct
     7981 cgggatgatc gcggaggctc aggccgacgg ggcgctgcgg gccgacgtcg gtcccgtgga
     8041 cctcgcgctg atcatgaccc tgcacgtcta cgccccgccg gggctgccgg gcgggcaggg
     8101 gttgccgcgg gtggtggaga tcgtcctcga cgggctgcgc gccgaccgtg ccaccccgct
     8161 gcccggcccc cgctccacct cggccgacct gcgccgctac accgccgtcg agcccggcgc
     8221 gcgctgatcg ccgcccgctc cgcccgggcg gcgctccttt ttgctcaggc ggcctcggcc
     8281 gccgacagca gggccgacag cttgtgcagg ccgcgagagg tgcgcgcctt gaccgtgccc
     8341 agcgggacgc ggagccgttc ggcgatctcc tgctgggtca gctcgccgta ataggccagc
     8401 tcgatcacct ggcgctgtgc gtgggagagc gcggccaggg cgcggcggac ccggtcgcgg
     8461 tcggccacct cctcgtcggc cgggcgctgc gcgggcgccg ccgcctcggc cacggcgtcc
     8521 agcggcaccg tggccaggcg gcggacgcgg aggtggtcca cggcgcggcg gtgcgcgatc
     8581 acgtacagcc aggcggcctg gctgcgtccc gggtcgtaac gcccgcggga gcgccaggcg
     8641 tcggcgaaca ccacctgcag caggtcctcc acgtcctgcg gcgagatgaa gcgccgcagg
     8701 taggagcgga gggccggggc gtgcgcgcgg tagctgtcgc tcaaggtctc ctcgtcggtc
     8761 cggccggtgg gccgctggtg gctgctcgcc gaagtgttcc ccatggcttg tcccgctccc
     8821 ctggaaaaac ctattcaaaa cttattcata gcggagcagg gaagggcggc acaatgtcat
     8881 cgggggcaag acacgatcaa ggcagggtcc gccggatttg ggacagagcc tcgcggaagg
     8941 tatctaccct gatcacgccc gcgggaagag tctccggcca gccccggccg cccaggacga
     9001 ggcgcgcggc cggccgcagc cgcggcagcc ccgccagcgg cgcggtgtcg ccggtcgact
     9061 cctgctgcga ccacaggaag accgccgccg gatgcagcct gcgcatggcg tgcgccagcg
     9121 cggcgtaagg ggtgcgggcg ccgagcaggc gcgtctccac accctcctcg gccagcgcgg
     9181 ccgacaacgc gtggaccggc agcgtgtgct gctcctcctc ggcgcaggcg agcagcaccg
     9241 gacgtcggcc ccgggggccc ggggcctgcc ggagcgcgtg cccgtgcaac gccgccagga
     9301 ggcggtcgga cagcaggtgc tcgacgtcga tgcccgcgcc ggtgccgtcc tggcggcggc
     9361 agaccgcgtc gaaggccggc aggaccaggc gctcccaggt ggagcgcacc ccctccgcgg
     9421 cgagcgccgc gtccaggagg gcggtgacgg cgtgactgtc gagcgcgtac gcggcccgca
     9481 ccagcgccgt cgccccgccg gtcgccgtgc tggcggtcgc cgtactggcg gtcgccgtgg
     9541 tggcgggcgt cgtgctggcg ggcgtcgtgc tgccgggcgc ggcggcggcc ggtgagccgg
     9601 cgggtggggt ggcggtgcgg gcgcggcggg cgcggcgggc ggcttcggac gggggcaggc
     9661 cctcggcgat cagccgctgc atctcccgca gccggtccag gtcgccggag tcgtagcggc
     9721 ggtggccgcc cgcgctgcgc cggctcgggc cgagcccgta gcgcaggttc caggtgcgca
     9781 gcgtgggcgc gggcacgccg agcagccgcg agacggcccc gatcccgtac ccggcctctt
     9841 cctcactcac cgccgtgccc tcgttctccg tgctcgtccc gctggtccgg acccgtttct
     9901 ggactcccgt gaccatcctt tcgcgatccg ccgacccccg gatgcaaccg gcgggggatg
     9961 ccttcgcgaa gacctatata ccgacaagga gacgacacgc atgaccaccg tgaccccgcc
    10021 ggcccgcacg cggaccggcg gcccgcagat cggcagccca cagaccagca ccgagatgag
    10081 ccgggtgcgc gagctggtcg agcggcgcct ggacgacctg ctcgaccagg agctcgcccg
    10141 gctgggcttc ctcggcgcgg agggcgtcgg cctggtgcgc cgccacctgg ccgcgttcgc
    10201 ccgcgacggc ggcaagcggc tgcgcccggc gttcgtgtac tgggggcacc gggcggccgg
    10261 cggcaccggc gagcacctgg agccggtgct gaacgccgcg tgcgccgtcg agctggtgca
    10321 cgtcgcggcg ctgctcctcg acgacgtcat ggacgaggcc gccgaacgcc ggggccgccc
    10381 ggcggcgcac gtcgcgctgg ccgccgagca ccggcgggcg ggcctgcggg gcgagcccgg
    10441 acgctacggc gagtcgcagg cgagcctgct cgccctgctc gccctggcct gggccgacgc
    10501 cgcgctgctc ggcgccgggc cgcacctggc cgacgcgctc gacgtcctca cccggctgcg
    10561 tgtggaggtc accgccggcc agcagctcga cctggccgcc acggccgccg gcggcgcgga
    10621 caccgcccgc acccgcacga tcgcgctcta caagtcggcc aagtacacca tcgaacggcc
    10681 gctccacctg gggcacgccg tggcgggcgg cgacccggcg gcccggcggg cgctgagcgc
    10741 gtacgcgctg ccgctgggcg aggccttcca gctccgcgac gacgtgctcg gcgtcttcgg
    10801 cgacccgggc cgcaccggga aaccggccgg cgacctgcgc cagggcaagc cgaaccacct
    10861 ggtcgcggtc gccagggaac ggtcgggacc gtccggcgcg gccctcctgg acgccgtcgc
    10921 cgccgcgcgg gacgacgacc ggacggccgc cgcccggggc gacgaccgga cggccgccgc
    10981 ccggggcgac gaccggacgg ccgccgcccg ggacgacgac cggacggcca ccgcccgggg
    11041 cgacggcggg acggccgccg ccggggacga cggcgggctg gtcgccgcag cccgcgagct
    11101 gatcgtctcc tgcggcgcgc tggagctggc ggagcggcgc atcgcggccc tggccgagga
    11161 ggcggacgcc gccctcgggc aggtgcccgg cctgccggcc gacgcccgcc gggcgctcac
    11221 cgagctgacc gtcctcgcca cggacaggag ccgctgatgg ccgggaccgg ccccgtcgtg
    11281 gtgatcggcg ccgggctggc cggcctcgcc gccgccgtgc ggctggcggc ggccgggcgg
    11341 gaggtcaccg tcgtcgaggc gcgggacgag ccgggcggtt gctgcggaac cgcccggctc
    11401 ggcccgtacc ggttcgacac cggcccgtcg gtgctgacca tgcccggcgc gctcgccgac
    11461 accttcggcg cggcggggga ggagctgcgg gactggctgc cgctgcgccg cctcgacccc
    11521 gcctaccggc tggccttcca cgacggcacc cacctggacg tcaccccgga cggcgaggcg
    11581 atggccgagc gggtgcggga gctgtgcggg cccgccgagg ccgcccgcta cctgcggtac
    11641 cggcggctgc tcggcgagct gttcgcggtg gagtggccgg cgttcatcga cgcggacatg
    11701 accaggctcg gcagcctggc ccgtccgctc gcgctggccc ggctggcggc gctgggcggc
    11761 ttccgccgcc tcgaccggct cgccgcccgc cacctctccg acgagcggct gatcaaggcg
    11821 cacaccttcc agtccctgta cgtcggcctg tccccgcagc gcgcgctcgg catctacgcc
    11881 gtgatcgcgc acatggacac ggtcggcggc gtgtacttcc ccgagcgcgg cggcatgcac
    11941 gcggtcccgt ccgcgctggc cgccctgctg gagaagctgg gcgcgcccgt ccggtacggc
    12001 gtccgcgccg cccgcgtcga gaccggcgcg ggcggcgtga ccggcgtgct gctggaggac
    12061 ggcgaacgcc tgcccgccgg gcacgtggtc gtcgcctgcg accggtacgc ggcccggcgg
    12121 ctgctgcccg gccgggccgc cgactggcgg atgcgccgcc cccgccactc gccgtcctgc
    12181 ctggtgctgc acgccgggct ggaccggccg ccggccgggc aggcacacca cacgctgcac
    12241 ttcggggggc agtggcggga gacgttcgcg gcgctggagg cggggcggcc gcagccggac
    12301 ccgagcctgc tggtcacctg cccggcgggc gacggcgagg cggcgccgcc cggtcacgtc
    12361 acgctcagcg tcctggagcc cgcgcccaac ctggagtcgg cggactggga ccggctccgg
    12421 ccgcgcctgg aggagcgcct gctcgcccgg ctggccgcgc tcggctacgg cgacctgtcc
    12481 gccgcgcccc gcctcgtcct cgacccgccc gcctgggccg cgctcgggca cacggcgggc
    12541 accccgttcg cgctcgacca ccgcttcacc cagacggcgt ggctgcgccc gtccggcgtc
    12601 gccaggcgcg tgcccgggct gcacttcgcc ggcatgcaca cggcgccggg cgtcggggtc
    12661 cccccggtgc tgatctccgg ccggctcgcc gccgaacgca tcctgacatc ccgctgaagg
    12721 acacccgccg aaggacaccc gttgactctc accgccagct acgaacgctg ccgccgcctg
    12781 cacgcccgct acggccgctc ctactacctg gccacgctgc tgctgcccgc gtggaaacgt
    12841 cggcacgtgc acgccctgta cggcttcgcc cgctacgccg acgagatcgt cgactccttc
    12901 accatgtccg ccgaccgccg ggccgcgctc gacgacctgt gcgaccgcac cgcgcgcggc
    12961 ctggcggggg agccggtcgc ggacccggtg ctgcccgcgt tcctgcacac cgtgcgctcg
    13021 ttcgggatca cccgggccga cgtggactcc ttcctcgccg cgatgcgcgc cgacctgtcc
    13081 gtgaccggct acgccaccta cgacgacctg ctcggctaca tggaggggtc ggcggcggtc
    13141 atcggcacca tgatgctgcc ggtgctggag gcgctgcccg gcgaggagcg ggccgcgcgg
    13201 gagccggcgc ggcagctcgg gctggccttc cagctcacca acttcctgcg ggacgtggcc
    13261 gaggaccacg ccaggggccg ggtctacctg ccggcgcagg acctcgccgc gttcggcgtg
    13321 gagccggccg acctgggccg cccccggacg gggcgggcgg tgcgcgagct gctggccttc
    13381 gaggcgcggc gggcccgcga gcactaccgg gccgcggcgc ccggcatcga cctgctggtg
    13441 gcctcgtccc ggccgtgcgt gcgggccgcc gtggagctgt acggggggat cctggtggag
    13501 atcgagcgcg gcggcttcgc ggtgctggag cggcgcgtac gggtgccgcg ccgccgcaag
    13561 gccgccgcct tcgcccgcca cctgctcgcc tccgccgagg cgggccgcca cgaacgccgc
    13621 gtccgggtgg agctgccgtg accccggcga acggccgcgg ccccgccacg ggcggccggg
    13681 actccgccac gggcggccgg gactccgcca cgggcggccg ggactccgcc acgggcggcc
    13741 gggactccgg cgccgccacg ggcgggcggg ggccggcggc ggggcggtgg tgctggacgc
    13801 catgggcggg gaccacggcc cggccgagat ggtggcgggg gcggtggcgg cgtggcgcgc
    13861 gcacggcgtg ccggtcgtcc tggtcggccg cgagccggac ctggcccgcg agctggccgc
    13921 ccgcgacgcc gccgagcgag ctgccgatcg tgcacgcccc ggacgcggtc cccatggccg
    13981 agcggggcgc gggcggcccg gcgctgcccg gctccagcct ggccgtcggc tgcggcctgc
    14041 tcgcgcgggg ggagggggcc gcgttcgtgt cggcgggttc gaccggcgcg gtggtctccc
    14101 aggccgtgcg gctggtgggc cgcgccgagg gcgtcctgcg tcccgcgctc gcgatcgcgc
    14161 tgccggcgct gagcggcggc gcgagcgtgc tcgtggacgc gggcgcgacc gccgacccga
    14221 cgccggagat gatggcccag ttcgcgctgc tcggcgccgg gtacgcccgc gccgtgctgg
    14281 gcgtgcccga cccggtggcc gggctgctgt cgatcggctc cgagcccggc aagggcaacc
    14341 ggctcgcccg gcgggccgag gagctgctgc ggaggcagcc ggcgcgtttc cacggcaaca
    14401 tcgagggcca cgacgtgctc tccggagccg tggacgtcat cgtcaccgac ggcttcaccg
    14461 gcaacgtcgt gctgaagaac gtcgagggct gcgtacggac cgcgctcacc atggtcgccc
    14521 aggcgggcct cgccgacccg gcagcgctgg cgggagtggc ccgccgctac gacccgcaga
    14581 cccacggcgg cgcggcgctg ctggggctgc gcggcaccgt ggtcgtcgcg cacggctcgt
    14641 cccgcgccgc cacgatcgcc cgcgcctgcg tggtcgcgca cgcgctgtcc ggggtgcggg
    14701 tggacgccgg cctcgccgcc gcgccggaac cggcatgagc gccgcccgcc ggtcagccca
    14761 gggggtcggc gccgttccag gtgccctcgc tgccgtacgg gacgaaccgg gcgaacagct
    14821 cctcgctgta ccagccgtcc cggcgcaccc ggtccaccac ccgcaggtgc gcgtcgtcgc
    14881 cgtaggcgaa gcggcgcatc gccgccgcgt cccgccacag ggagaacgtg gcctgccggg
    14941 ccagcggcca ctcgccgacc ccgaccgagg ccaggcagcc gtcctgccgg gccagcagcc
    15001 ggtccaccgg cggcaccgaa cggtagaagg cggccagccg ccgcgccctg atcgaggcgc
    15061 gggtgagcac cgcgaccggg cccccgccgt cccgccgccc gccggcgagc cggccgaagg
    15121 gggagcggcc gccccaggtg ccgcgcgcgg acaggggcgc cagccggacc tgccaccgct
    15181 cgtcggcctc ggcccgccac cgggccgcga cgggggaggc gcggaggaac gcctccaggt
    15241 cggcctcctc gcgccagacc gcgaacagcg cccaccggcg caggtccgcg ccgagcgaca
    15301 tcgaccggcc gcgcccggtc ccgagcagcc gccagaacgt caggcccgcg gtgccgcgca
    15361 gcagcgggcg gtcgaaggcc atgtggcgca tggcgtccac ggagccgtaa cggatgaggt
    15421 ggaacgaggc tatgggtgca gcggtgctgt cggtcatcgt cggctacctg ctggggtcga
    15481 tcccggtggc ggtgctgctg gcgcgcggcc acgggttcga cccgcgcgcg gtgggcgacc
    15541 gcaatcccgg cttctggaac gtgaaggagc agctcggctg gcggtcggcc gtgccggtgt
    15601 tcgccggtga cacgctgaag ggcacgctcg ccgcgctggc ggcgctgctg ctcagcggcg
    15661 ggcacacgac cgggccgggg gtggtggcgg gggacagcgt cgtgcccgtg tacctggcgg
    15721 tggcggccgc gatggcgggg cacgcctggc cggtgttcgc cgggttccgg ggcgggcggt
    15781 cgatcctgac cttcgcgggc ggggtggcgg tcatctgccc gcccgcgttc gcgctggccg
    15841 tggcggcgct ggtggcggtg gcgctggggg cgcggtcgtt cgccgtgggg gcgcgggtgg
    15901 cggtgttcgg cgtgcccgcg ctgcagctgc tgttcgcccc ggccgaggtg gtcgcgggga
    15961 cgggggcgct gatgtgcctc atcgggctgc gtttcggcca ggccgcgctg tcgtcccgcc
    16021 ggagctgacc gccgggtccg ccggggccgc ctgggccgcc gggttcgccg ggtccgccgg
    16081 gttcgccggg ttcgccgggt tcgccgggta cgtccggccg cgccaccgcc gtaccgggcg
    16141 gagcgtggcc tgggtgaggc ggaccgcggc ggccgggtcc agcagcggcg acagcagcag
    16201 ggccgcgccc ggccgggtgt agctgccgcg cagggcgccg gtcagcagca gccggacgcc
    16261 gagcagcgcc aggtccagcc ggctcggccg gccggcggcc aggcgcagcg cgggcagggc
    16321 cgccgtcagc cagaccacgg ccaggtcggc ggcccgccag ccggcgccgg tgacgtcccg
    16381 gagcggcagc gaccggcccc actcgcgcca cagctcggcc gtcgagtcgt gcatgtcgac
    16441 ctccagcagc ccgccgccgt cgaggaagcc gatccgccag ccccgccccg ccaggaaccg
    16501 ggcgagcgcc acgtcgtcgg tcatgtgccc gcgcaccgcc gcgaaaccat cgatctccgt
    16561 catcgcgtcc cgccggaagg cgaggcactg gccgttggcg agcacccggt gcggcgggag
    16621 cgggtccgcc cggccgaccg ggccgaaccg gtagaccagc gtggccagca tcgacgcgtg
    16681 cagggcctgt tcgagcgggc cgtcgcaggc gaagcgcggg gcggcgctga ccaggtcgcg
    16741 gccgtccagg gcgcgggcca gcgcgccgaa caggccgggc tcggggcggg tgtcggcgtc
    16801 cagcgtcacc acgacgtcgc cgcgggcggc cgccacgccc tggcgcagcg cccactgctt
    16861 gccgacccag cccgggggca gcggctcgcc ggtgacgacg gtcgcgccga gcgcggcggc
    16921 gagcgggccg gtgccgtccg tggagcggtc gtcgacgacg atgacctcgg cgacggccgg
    16981 gtccttcagc gcggcccgca ggcacggccc gatcctggcg gcctcgtcgc gggccggcac
    17041 caccaccgag atcagggcgc cgggcgcggc ggcggcccgg agcgggggca gccgccgccg
    17101 gccccgcgcc agccgcgcca gcaccacccc ggccgccacc gcctgcgccg ccccgagcag
    17161 ccgccccccg gcgcgcgccg tccccgcgag acggcggctc atcggagcgc cgcctcgcgc
    17221 gggtcgccga agtcctcgcg gacgagcccg gcgacgatcc tggcccccag cgtcaccatg
    17281 ggcagccccc ctcccggatg cacgctgccc ccgaccaggt acagcccgcg ccgcggcccc
    17341 cggttgcccg gccgcaggaa cggcgccagc cgtccccggt aggcgctgcc gtagatcgcc
    17401 cccgcccagg ccccgtaccg gtcgcgcagg tccgccggcg tgaggacgtc cacgaagcgc
    17461 agccgcccgg ccaggtccag gccgcgcccg gcgagccgct ccagcaccag gtcccggtag
    17521 gcgtccacgc cgatgcgcca ccggccggga tcgcgggcgg gcacgttgac cagcatcgtc
    17581 cagttctccg tcccggccgg cgcctggccg gggtcgtcca cggccgagca gccgacgtag
    17641 atcgtcgggt cgtccggcgg ctcgcgccgg tcgaagatgt cggcgaactc ccgctcgtag
    17701 tcgcccgaga acaccaccgt gtggtgcgcc agcccaggcg tgcgcccctc gacgcccgcc
    17761 atcagcagga acgccgacga cgacagcccc agcccggcca gccggcgcag ccgccgccgg
    17821 tccggcagca ggcggccgta cagggcggcg gcgtccacgc cggccaccac cacgccggcc
    17881 cgctcgtgac cgccgcccgc gagccgcacc ccggtcacct cgccgccgcg cgcggtgacg
    17941 gcctcgaccg gcgcggacag gtgcaccagc acccccgcct ccttcagcag ccccgccagg
    18001 tcctcggcca gccggggcag gccgccgggc acgtaccagc cgccctcgcc gtgctccagc
    18061 gcgggcacgc agcccagcgc ggccggcgcg cggtacgggc tggagccggc gtaggtggcg
    18121 tagcggccga cgtactggcg cagccgcggg tcgcggaaga agcggcgggc cagcccgtcc
    18181 agggtggcgg cgggcgccac ggccagcagg tcgcccaggc gggccgcacg cggcgggcgg
    18241 ccgagcggcc cggcgaagaa ggtgcggccc gccgcccgca ggcagccctc ggcccaggcg
    18301 tggaaggccc gccacgcggc gccctcgccc ggcgcgagcc ggtccacctc ggccgccatg
    18361 cgctccgggt cccgccgtgc cgtcagcacg ctgccgtcgg cgaagcggta gcggcacagc
    18421 tcggccggct ccacgaacgc gcgccgcagc cccaggtctc ggaagaggcc cggcatggtc
    18481 agcagcgacg ggccctcgga gaaggagaac ccgtcgcgcc ggtgctcggc cagcttcccg
    18541 ccgaggcgcg gcagccgctc gtacagccgc acccggtgcc cctgcccggc cagcagcaac
    18601 gccgacgcca tcccgccgac gccgcccccg accacgatca cgtccgtcac gtcgtcaccc
    18661 ccgccaccgc gtcgccctcg ccaggagcgg tcacctctgc cacggccgcc atccgttccc
    18721 cttctgccac agccgccgcc acgccagcgc ggcgaacacg cccatcgaga tccctccggc
    18781 cgcggcgacc agcgggtccg gcggctggaa caccgccgcg aaccccaccg tctccatgac
    18841 cgccatcgtg gtgtagacgc ccaccgcgcc ccgcgcgggc gcgtcgcccg cgatccgccg
    18901 cagcagcagc atgaccagcg cggacaccag cagccagccc gcgtagttgc tcagcgggat
    18961 gccccggtac gggcccggct cggcccacgt ccacaggccg agcccgacca tctgcgggtc
    19021 gaggaagagg tcccacgccg tcagcgcgag cgcccccacg gccggccggg cccgccccgt
    19081 cgtgatcgcc gccgccaccg cgtacgcggc cagccccatc ccgccccacg ccagcgccac
    19141 cacggcggga acgccgccga gctgcggcca cagcaggtcg gtgtagcggt agtgcccgaa
    19201 cgggaacccg gtgcgcaggc ccactgcctc cgccgcgtac ccggcgagca ccgccgccgc
    19261 gaacccggcc gccgcccgcc gcgctcccca ggccgccgcc gtgaagccga gcacgctgac
    19321 cgccagcacc gccacgacga tcccggtgta ccgcaccggc tcgggactga tgccggacag
    19381 gacctggcag gccaccatga ccacgagcgc cgtcagcccg accgcccgcg ccgtcccggc
    19441 cgcggccggg accgccgtca ccggcgcgct tcgcgtctca cccacacctt ctctttcggg
    19501 cgcgccgcgc gtccggatgc atcagctcag gccgggccgc cgaccctcgc caagagcgcc
    19561 aagaccgtca gatgtcacaa tcatcaacca attgccagat agcaaatgat gcgagcgcat
    19621 cagtaggccc gatctagtaa cctcgcatgt ggatccacgg agacatctgc ctgtgtgtcc
    19681 tgttccagcg gcgatggtca cgcacgggcg aagatcaggt ttatggtagc ccgcatcgtg
    19741 acatcaccag cgtgcttggc cagtgattcc aacgacgagg gcggacatga gtgacacgac
    19801 agccggcggg tcgggcacga ccacccgcgc cggcgccgag gtcggcgagt ccgagctgcg
    19861 cctgctcctc gcgggcctga cggcggtcag ggacggcgac ttccgcaccc ggctccccga
    19921 ggacgccgac gggctgctcg gcgagatcgc ctcggtgttc aacggcatgg tggaccagct
    19981 ctcgctgttc acctcggagg tcacccgggt ggcccgcgag gtcggcaccg agggccggct
    20041 cggcggccag gccgaggtgc ccgcggtgtc gggcacctgg aaggacctca ccgagtcggt
    20101 caacgccatg gcgggcaacc tcaccgacca ggtgcgcagc atcgcccagg tcaccacggc
    20161 ggtggcccgc ggcgacctct cccagaagat caccgtgcac gcccggggcg agatcctgga
    20221 gctgaagaac accgtcaaca caatggtcga ccagctctcg tcgttcgccg acgaggtgac
    20281 ccgcgtggcc cgcgaggtcg gcaccgaggg ccagctcggc ggccaggccg acgtcaaggg
    20341 cgtcgccggc acctggcgcg acctcaccga ctcggtgaac ttcatggccg gcaacctcac
    20401 cgaccaggtg cgcaacatct cgcaggtggc cacggccgtc gcgcgcggcg acctgtcgca
    20461 gcgcatcacg gtctcggcgc gcggcgagat cctggagctg aagaacaccc tcaacacgat
    20521 ggtcgaccag ctctcgtcgt tcgccgacga ggtgacccgc gtggcccgcg aggtcggcac
    20581 cgacggccgc ctcggcggcc aggccgacgt caagggcgtc tccggcacct ggaaggcgct
    20641 cacggagtcg gtcaacgtca tggccgacaa cctcaccgcc caggtccgca gcatcgccga
    20701 ggtcaccacc gcggtcgcca agggcgacct gacgcagaag atccgggtgg acgcccgggg
    20761 cgagatcctg gagctgaagg agaccatcaa cacgatggtc gaccagctct cggccttcgc
    20821 cgacgaggtc acccgggtgg cccgcgaggt cggcaccgag ggcaacctcg gcggccaggc
    20881 caccgtgcgc ggcgtgtccg gcacgtggaa ggacctcacc gacaacgtca acgtcatggc
    20941 ctccaacctg accagccagg tgcggagcat cgcgcaggtg gccacggcgg tggcgcgcgg
    21001 cgacctgtcg cagaagatca ccgtcgaggc caagggcgag gtcgccgcgc tggcgcagac
    21061 gatcaacacg atggtcgaca cgctcggcgc gttcgccgac gaggtgaccc gggtggcccg
    21121 cgaggtcggc accgagggcc agctcggcgg ccaggcccgg gtgccgaacg tggccggcac
    21181 ctggaagaac ctgaccgaca acgtcaactc gatggccgac aacctgacca accaggtgcg
    21241 cagcatcgcc caggtcacca ccgcggtcgc gcgcggcgac ctgacccgca agatcgacgt
    21301 ggacgcgcgc ggcgagatcc tggagctgaa gaccaccatc aacacgatgg tcgaccagct
    21361 gtcgtcgttc gccgccgagg tgacccgggt ggcgcgcgag gtcggctcgg agggccgcct
    21421 gggcggccag gccgaggtgg agggcgtctc gggcacctgg aagcggctga ccgagaacgt
    21481 caacgagctg gccggcaacc tgacccggca ggtccgcgcg atcgccgagg tgaccagcgc
    21541 ggtcacctcg ggcgacctga cccgctcgat caccgtggac gccgagggcg agctggccga
    21601 cctcaaggac aacatcaact cgatggtcaa gtcgctgcgc gagaccacca cggccaacga
    21661 gcagcaggac tggctgaagt ccaacctcgc ccgcatgtcc gggctcatgc agggccaccg
    21721 cgacctcgcc accgtcgccg agctcgtgat gaacgagctg gcgccgctcg tctcggccca
    21781 gtacggcgcg ttcttcctgg ccgaggagag cgagctgaag ctgttcagcg cctacggcta
    21841 cccggtggac gccgaccgcg ccccccgctt ccagctcggc gacggcctca tcgggcaggc
    21901 cgcccgcagc cgccgcacga tctcgctgac cgagaacatc cccgccggcg tcatcaccat
    21961 cgactccggc ctcggcaaga tcatgcccgc ctcgctggtc gtgctgcccg tggtcgtcga
    22021 ggagcaggtg ctcggcgtga tcgagctggc ctcggtgcag gagttcacgc ccgtgcaccg
    22081 ggcgttcctg gagcagctga tggagacgat cggggtcaac ctcaacacga tcgtcgccaa
    22141 cgcccgtacc gacgagctgc tgaaggagtc gcagcgcctg gccgccgagc tgcaggcccg
    22201 ctcggaggag ctgcagagcc agcaggagga gctgcagcgc tccaacgccg agctggagga
    22261 gaaggccgac ctcctggtca gccagaacca ggacatcgag gccaagaacc tggagatcga
    22321 gcaggcccgg caggagctgg aggaccgcgc ccagcagctc gcgctcgcct cgaagtacaa
    22381 gagcgagttc ctggcgaaca tgagccacga gctgcgcacc ccgctcaact cgctgctcat
    22441 cctggcccag ctcctcgccc agaaccacac gcgcaacctc acgccgaagc aggtcgagta
    22501 cgcggagatc atccactcgg ccggctccga cctgctgcag ctcatcaacg acatcctcga
    22561 cctgtcgaag gtcgaggcgg gcaagatgga cgtcaacccc gaatgggtgc agctccgccg
    22621 cctgctcgac tacgtcgaag ccaccttcca gccgatgacc agcgagaaga gcctcgactt
    22681 caccatcgtc accgcgcccg gcatccccaa cgagctgctg accgacgact cccggctgcg
    22741 ccaggtgctg cgcaacctgc tgtcgaacgc ggtcaagttc accgagaccg gcaaggtgga
    22801 gctgcgcatc gagccggccg ccccgtccga gctgcccgcc accgtgcggg ccaacgggcc
    22861 ggcgctcgcg ctgcgggtcg tcgacaccgg catcggcatc cccgagcagc agctcgaagt
    22921 catcttcggg gcgttccagc aggccgacgg caccaccagc cgcaagtacg gcggcaccgg
    22981 cctcggcctg tcgatctccc gcgagatcgc ctacctgctg ggcggcgcga tcagcgtgca
    23041 gagcacgccg ggacagggca gcgtgttcac gctcttcctg ccgatcgccc acccggcctt
    23101 cgccgacggc tccgcccgcg ccgccgcgtc cgccgccccg caggagggcg cggagcaggc
    23161 cggggagtcc gacgcgaccg ggccgtcccc ggccgccgac ggctcctccc agcaccggcg
    23221 gctgctggtg atcgagcagc gggccggcgg cctgctgtcg ctggtggccg agagcgtggt
    23281 gcgcgagctg accgacagcc gcgacgacac cgtcgagatc atcagggcgg cgggggccga
    23341 ggaggccgcc gccacgctgg ccgcccagcc ctgccactgc atggtcctcg acctcgacat
    23401 gccggacctc gcggccttcc agctcctgga ggccatggac ggcgacccgg ccctcgcggt
    23461 cgtgcccgtg ctggcctaca gcaactggcg caccacgtcc cagcagaagg cccggctgcg
    23521 cgagcgcgcc gagagccagg cgctggagct gctgtccagc ctggacgagc tgcgcgagcg
    23581 catcgccctg cacctcaccg ccgagcagcc cggcgacgtg ctgccgctga tccggcccga
    23641 c
//
