LOCUS       NZ_JAKRKC020000002     22964 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Actinomadura luzonensis strain ATCC 31491 Contig00006, whole genome
            shotgun sequence.
ACCESSION   NZ_JAKRKC020000002
VERSION     NZ_JAKRKC020000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura luzonensis
  ORGANISM  Actinomadura luzonensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Genome draft of Actinomadura sp. ATCC 31491
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Genome draft of Actinomadura sp. ATCC 31491
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
REFERENCE   4  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
REFERENCE   5  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
REFERENCE   6  (bases 1 to 3173380)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. v1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 89.6x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022664455.2-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:46:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,232
            CDSs (total)                      :: 10,155
            Genes (coding)                    :: 10,004
            CDSs (with protein)               :: 10,004
            Genes (RNA)                       :: 77
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 36 of 151
            Pseudo Genes (incomplete)         :: 126 of 151
            Pseudo Genes (internal stop)      :: 3 of 151
            Pseudo Genes (multiple problems)  :: 14 of 151
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 819506
            Orig. end                         :: 842470
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAKRKC020000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22964
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="2"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22964
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22964
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12964](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12964)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            complement(362..1306)
                     /locus_tag="MF672_RS34015"
                     /old_locus_tag="MF672_034015"
     CDS             complement(362..1306)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656213.1"
                     /locus_tag="MF672_RS34015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034015"
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_242382748.1"
                     /transl_table=11
                     /translation="MDVLTDLLNRARARNALVRRLVQPPPWGITYADAPPLTVAAALGG
                     RAAIRAGDGPPTALAAGDIALVTAPGGYTITDDPATAPQYVIRGGRKFLPGGAPVEWTG
                     PEPVPRTYGAGTAGGPAGATVMLRGVYDLRGDVAARLLGLLPPLAVVPAGPRTRALLGL
                     LSAEAASDEPGQDAVLARLLDLILVIALRAWCTRPEAAPPAWYRALSDPAIGEALRLLH
                     EHPARRWTVAALAGEVGLSRAAFAQRFTGLVGRPPLGYLTDWRMTLAADLLRDGRETVA
                     EVARRVGYQDAFAFSVAFKRARGATPSAWRAAR"
     gene            1389..2096
                     /locus_tag="MF672_RS34020"
                     /old_locus_tag="MF672_034020"
     CDS             1389..2096
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012334.5"
                     /locus_tag="MF672_RS34020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034020"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_242382749.1"
                     /transl_table=11
                     /translation="MTRSIAVFGTGPGVGQAVARRYGKEGYEVVLVARRREPLDRLARD
                     LAAEGVTAHVITGDLGRSGDVPALAAQVRAAVGDPTAFYYGPVPSGLTFVPAVELTPGH
                     LAERLEITLHTLLALVGEFLPAMAERGDGAILTAQGAAAAHGRPYMSGWPPVLAAQRNY
                     LQSLAAEVAGQGVYVGMLYIGSRILGTSFDDDYRRRQARGEPVPDLPAADPADLADLLW
                     SMHARRDRHETIV"
     gene            2138..2668
                     /locus_tag="MF672_RS34025"
                     /old_locus_tag="MF672_034025"
     CDS             2138..2668
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.5"
                     /locus_tag="MF672_RS34025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034025"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_242382751.1"
                     /transl_table=11
                     /translation="MTRPTVTLRRIELADWPAVHAWARLPESCRYQTWGPNDEEQTRAY
                     VAAAAGEWSRTPRRALPYAAHVDGEVLGMGTLHLRDAAHRQGEITYIVHPRAWGRGVAT
                     AIGAGLLGTAFAELGLHRVYATCDPRNAGSARVLAKLGMTCEGRLRHTTLIRDGWRDSE
                     LFSILEHEWRPPA"
     CDS             complement(2704..2934)
                     /gene="allorf_0822210_0822440"
                     /locus_tag="allorf_0822210_0822440"
                     /protein_id="allorf_0822210_0822440"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGCPSVAHDHGCVRWKRRRPARPRGPYGRLGAAPLAGGPWTGERR
                     RAARTRGRGPRDGTRPCRDRSVPTLGTSPPC"
     CDS_motif       complement(2821..2934)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MGCPSVAHDHGCVRWKRRRPARPRGPYGRLGAAPLAGG"
                     /locus_tag="allorf_0822210_0822440_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2704..2820)
                     /prepeptide="core"
                     /locus_tag="allorf_0822210_0822440_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.70"
                     /molecular_weight="4107.6"
                     /monoisotopic_mass="4105.2"
                     /core_sequence="PWTGERRRAARTRGRGPRDGTRPCRDRSVPTLGTSPPC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGCPSVAHDHGCVRWKRRRPARPRGPYGRLGAAPLAGG"
                     /leader_location="[2820:2934](-)"
                     /alternative_weights="4125.6"
                     /alternative_weights="4143.6"
                     /alternative_weights="4161.6"
                     /alternative_weights="4179.7"
                     /alternative_weights="4197.7"
     gene            2933..4351
                     /locus_tag="MF672_RS34030"
                     /old_locus_tag="MF672_034030"
     CDS             2933..4351
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017583542.1"
                     /locus_tag="MF672_RS34030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034030"
                     /product="amidase"
                     /protein_id="WP_242382753.1"
                     /transl_table=11
                     /translation="MQLHEYAKYDAVGLRTLIEAGEVTAGEVEAAARQALDQVNPHVNG
                     LALPPFQPALGHAGDGPLTGVPFLIKDHGPVAEGVPFSLGSRALPGIPAWRDTDLMTRF
                     RAAGLVTLGLTTVPELCVSFSTEPLRHGPARNPWNPGRGVGGSSGGAAALVAAGAVPVA
                     HASDGAGSIRIPASCCGLVGLKPSRGRVPCGPDAGEPMLGMAYEFALTRTVRDAARLLD
                     AVHGPGVGDKYTAPPPRGPYAAEVGRDPGRLRVAVTTESWAGTAVDAEVAAAAVRAGQA
                     LERAGHLVTTAGPAVVWDDVVRAWVCESVAIASTLLLAPRRPDEGLMEAVSRQFLKTAE
                     EYSALDMLAAFDAQNRVSRAVGAFFTGYDLLVTPTLGRLPAPHGVLRYDDPEQTLTGWL
                     AALTEYGPFTQVFNVTGGPAISLPLGHSEDGLPIGVQLAAGYGREDLLLQVAAHLEEAL
                     PWRDRVPPIHAGGR"
     gene            complement(4451..4867)
                     /locus_tag="MF672_RS34035"
                     /old_locus_tag="MF672_034035"
     CDS             complement(4451..4867)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077214.1"
                     /locus_tag="MF672_RS34035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034035"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_242382755.1"
                     /transl_table=11
                     /translation="MPTAREIMTPDAECVNADEPVLVAAEKMARLDVGSLPICGTDNRL
                     KGMLTDRDIVVKVLAAGKDPAKTVAGELAQGEAVTIGADDDAREILRTMAGHKVRRLPV
                     IDGHSLVGMVALAEVARALPDATVSDLLDAVTSD"
     gene            complement(4975..6552)
                     /locus_tag="MF672_RS34040"
                     /old_locus_tag="MF672_034040"
     CDS             complement(4975..6552)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.5"
                     /locus_tag="MF672_RS34040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034040"
                     /product="acetylserotonin O-methyltransferase"
                     /protein_id="WP_242382757.1"
                     /transl_table=11
                     /translation="MDQGNVLSPEIASGALDEADAARLGRMAQVARDGGDGPYGLRFDH
                     AGLLVFPRSAEAALAGLPVVRRLPSVIVKERLARRYGLAGPEVTIAHLDAGGGRTLELF
                     LATGCPPEVAGDERLHERETHLAYEAPAASLGVLEALRADGCLPDGGGFNPGEGPSGRS
                     VFYFRRRGGDRLEIVAAGQARAELARHLGAPEERRHMLGLLTGAWTTQALRTAAELGVA
                     DLLHARDRTLGELARATACPADRLGRLLRYLEQLGVVRRAGEAYALTPLGTTLARDSPS
                     SLHGVALLYGGLFYRSFGELPGAVRGAAPSGFELAYGLAPFAHLDACPGDAAVFQLAMS
                     DQCRDVFDAVADRLDLDGVGTVTDLGGGTGALLGRLLDAAPHVTGVLFDTPATVAAARP
                     ALVARHGGRVSAVGGDLFSRVPGGDLLVLSRVLHDWDDAACARILARCREATRPGGRLA
                     VVERLLPERAGEPSLAAAWDVHMMVNNAGGRERTLEEYRELLAAAGFALTSRAGLPLDV
                     HLLEAVAR"
     gene            complement(6604..7398)
                     /locus_tag="MF672_RS34045"
                     /old_locus_tag="MF672_034045"
     CDS             complement(6604..7398)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS34045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_034045"
                     /product="hypothetical protein"
                     /protein_id="WP_242382758.1"
                     /transl_table=11
                     /translation="MTDTYRAGSHPAFIAALVGLREAAGQPSYSTMHQLSRAPGVPKEL
                     PASTVNDILTGKRERLPDWGLVASFVKVCHRHAELTGLPTDALGTVEQWQARWRAARSE
                     QPARPRVTGSHDLFRTPADEAERRTTRTVDRLMRLAGDGDPDAACRLAIIALLTGDRSA
                     AGYWLHVAARHRHPHAEALAAHPRPAELAAELAFALGQAYEEEGPAKLVIARFYYRLAA
                     EHGHPAAGERLRVLRAVPFGKLLPAPLFSPAPAGTRPGVHRP"
     misc_feature    7409..7424
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 18.98"
                     /tool="antismash"
     misc_feature    7435..7448
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.71"
                     /tool="antismash"
     misc_feature    complement(7436..7449)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.16"
                     /tool="antismash"
     misc_feature    7436..7450
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.75"
                     /tool="antismash"
     misc_feature    7437..7450
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 11.9"
                     /tool="antismash"
     gene            7745..7936
                     /locus_tag="MF672_RS34050"
                     /old_locus_tag="MF672_034050"
     CDS             7745..7936
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS34050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_034050"
                     /product="hypothetical protein"
                     /protein_id="WP_242382761.1"
                     /transl_table=11
                     /translation="MPLLTARPSSMAYRSDAPCPADEHLLVTLVTTWVLATGRRPPAAR
                     PGDLTAEELIEFWADDRL"
     gene            7957..8139
                     /locus_tag="MF672_RS34055"
                     /old_locus_tag="MF672_034055"
     CDS             7957..8139
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS34055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_034055"
                     /product="hypothetical protein"
                     /protein_id="WP_242382762.1"
                     /transl_table=11
                     /translation="MFTTRQLLTLTMALTVAAITCALVLAGGVAWPGALLSGGGAGGAT
                     LAALPRLLTRRDPHP"
     gene            complement(8154..10004)
                     /locus_tag="MF672_RS34060"
                     /old_locus_tag="MF672_034060"
     CDS             complement(8154..10004)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592961.1"
                     /locus_tag="MF672_RS34060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034060"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_247815556.1"
                     /transl_table=11
                     /translation="MTADGELVRPYWRLDEPETDLGLRRMIGRLPATAGAVLAVVARAS
                     PRHAALVLALEVVSAAATACGLLATAGALERLLSADLVTALPAMGLVAGAYALRGAVGA
                     ATAAAHARVPPAVRRVAEGELFAAALRVELAAFDDPDFFDRMQRARDRALFHLGRAVDN
                     AVELVSAALAVGAALVAVAVLHPALLAVLLVVVLPSGWSVQRSTRLAYRFMTRTVTLNR
                     RVRMLTDLAMGREPAAEIRACQAEGFLLREYGAVADALRDQEVGVAVAQVRVRAAGRAL
                     SGLGTGLTFAALGGLLQAGWIPLAVAGAAVMAVRTGSASLSRLVLAANQLLEQGLYVRD
                     YQRFVAESRTRTAAGGTRPAPARPELVEVRDVCFRYPGGDRPALRGVSLTARAGRTVAL
                     VGENGSGKSTLAKILAGLYAPGRGSVRWDGVDLAELDPRDVADRITLVPQAPVRWPHTA
                     RVNVRAGRHDRPDPGDLALEAAARLSGADAVVAGLPSGWETLLSKAFHGGHELSGGQWQ
                     RLAIARGLFRDTPLIVWDEPAAPLDPRAEFALYESLRGLAAGRVVVLITHRLASARNAD
                     HIYLLHEGVVAEHGSHDELIAAGGRYAELYGLQARMYAPA"
     gene            complement(10001..12964)
                     /locus_tag="MF672_RS34065"
                     /old_locus_tag="MF672_034065"
     CDS             complement(10001..12964)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="MF672_RS34065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034065"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_242383224.1"
                     /sec_met_domain="DUF4135 (E-value: 1.1e-74, bitscore:
                     249.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-30, bitscore:
                     103.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHANAVSDVVLGCLLEPALAGLAAQLDAVDGLTEAERLVLRSAAE
                     ASALHAARLRTNRVLLLELNAARISGRLTGADARARWREWEEGAATPEFWDGLAGHYPT
                     LRPRLDRVVGNRCAAALELARRFAADRDKLGALTSGERVGEQGGEQGGELRAGELRAGE
                     LRGVAFGAGDSHRGGRTVAVLRLSGGLLVYKPRSMAVDVALSRFLAAVLGDDPWRISVP
                     RVVTGDGYGWAEHVAHRYCAGEEELRAFYRNLGHWLAVMRLIGGSDLHAENVIACGPVP
                     TVVDCETLFTPQPPMPDSAYGLAVDRASRLVGGSVLGTGLLPGRGLALGWRGVDMSAIG
                     ALPGQQPAPKLPVILDAGTDEARIGQAETPIRAAVNHPSPDPVLGAYWDRIVAGFTELS
                     DRLRDLDRRGELEPLLAGFAGLPVRVVARSTETYAELARMLWHPHALHDEPAARAKAVS
                     LLTRQSRNLPGRPDDPAVIEAEVAELLDSDVPFFSTTPRVGRLTGPRGTSWGPEQDLVA
                     AALGRWRSADLGLDRRVIQSTLVSAYLNEGWLPDHRALLPSGRDLTRLDRRRRAVAAKI
                     VGDLVASAIRAEDGTATWIAPVLNPTGWAVLPLGPDLYGGLTGVAVLLAAYEHETGHGR
                     ADPVPGVPSLLADVLRTMRKAEDQATVELTTRRRPPPAGGYLGLGSRVWGWRLLRRLGV
                     VGDEEARERAAKLVPDELVPDEQALDLVSGLSGMVVPLLALDDPAAAGLAVRIGRRLVA
                     AARLRDGTAWWDSEFFPSGLGGVAHGATGIGWALARLGAATGDRDFTEVAEAAFAYEET
                     LYVPSAGSWRDLRQPDITAAAWCHGAAGIGVVAADRLRHGGDPERWLDVLRRAAAAAKA
                     GGMGWNHTLCHGDLGAWEVIDLALAAGVAEPGMTRDILDAHTLGSLEEHGPVSGFAREA
                     FCPGLLPGLGGVAYQLLRMHPGCPLPSVLLPDPDLPSGSLLDGARPVPGERVGGGRR"
     gene            complement(12969..13217)
                     /locus_tag="MF672_RS34070"
                     /old_locus_tag="MF672_034070"
     CDS             complement(12969..13217)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF040361.4"
                     /locus_tag="MF672_RS34070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034070"
                     /product="DUF6229 family protein"
                     /protein_id="WP_242383226.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRMTAELAERIVAGWRSGADTVDGWDNPAGPLFAGGEYAEADIT
                     MESIFAASGCTGVGCPPPPESGHCGTACTWSAGLECC"
     gene            complement(13315..14967)
                     /locus_tag="MF672_RS34075"
                     /old_locus_tag="MF672_034075"
     CDS             complement(13315..14967)
                     /EC_number="3.6.4.12"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0043138 - 3'-5' DNA helicase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547770.1"
                     /locus_tag="MF672_RS34075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034075"
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="WP_242383228.1"
                     /transl_table=11
                     /translation="MRHRFGWRGRRLRATARRRFGWQRLRPGQQEAMEHLLAGRDVLLV
                     MPTGAGKSAVYQIPAQLLDGPTVVVSPLIALQRDQVAGLLRADAGGAVAVNSTTSVDSG
                     LEQVTAGAAEFVFLSPEQLAKPEVVERLAAARPSLVAVDEAHCVAAWGHDFRPDYQRLG
                     KVIARLGHPPVVAMTATAAPNVREEIVRALGLRDPVEIVRGFDRPNIALEVRRFVREED
                     KSRALAEDAAARDGLGLVYVATRKDTERYAAALAERGRRAEAYHGGMRAAERARVQELF
                     TSGDLDVVVATSAFGMGIDRPDVRWVLHAAPPESPDAYYQEIGRAGRDGAPATAVLFYR
                     PEDLGLRRFFTGGRADAATLLRVATLVRGHAGEVPARELAGLLELSASQLTRLVNLLER
                     AGALAVTDAGALRYADPALPPERAAERAAGLDEARHHLDRSRLDMMRGYAETRGCRRRY
                     LLAYFGEPYAAPACGACDSCRDGAAARPEPAAAPAEEGPFAVQAKVRHKTWGEGTVMSR
                     EPDRITVLFDSVGYKTLALSAVDRVLEPAGTGS"
     gene            15135..16010
                     /locus_tag="MF672_RS34080"
                     /old_locus_tag="MF672_034080"
     CDS             15135..16010
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012571.5"
                     /locus_tag="MF672_RS34080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034080"
                     /product="phenylalanine 4-monooxygenase"
                     /protein_id="WP_242383230.1"
                     /transl_table=11
                     /translation="MDEHPPRTPTTADGRLGRAADHPGMRDPRYLARRRWFAQLARGHR
                     VGDPAPRVEYRPGEHAVWRAVRRALEDAHRAHACREVLSAREAVRFPADRLPQHAEVGA
                     QLRRLTGFDFTLAGGVVANERFLGSMARGYFHAVQFVRHPAVPMYTPEPDLIHDVFGHG
                     IHLAAPVFAAVYRLIGEAAARLRTGHALQIVSDLYWYTLEYGVVEDGGATKAYGAALLS
                     SYGELGRFRAADVRELDVPAVLATPYDIAGYQPVLFRARSLAHVADTLAAFLGGLDDDT
                     ALAARPPAAP"
     gene            complement(16096..16452)
                     /locus_tag="MF672_RS34085"
                     /old_locus_tag="MF672_034085"
     CDS             complement(16096..16452)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015928.5"
                     /locus_tag="MF672_RS34085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034085"
                     /product="peptidase inhibitor family I36 protein"
                     /protein_id="WP_242383232.1"
                     /transl_table=11
                     /translation="MRTTHVTRIAAASAAALAALTLCSAPAAAAARAGDICLYSGRNYT
                     GASWCWNPGNGYVDVPPALHDNVASFRAGANGCFINWIQVPNRKETRVVRDGDYRSVYD
                     NDFGGKIDAVAPTC"
     CDS             complement(16556..16648)
                     /gene="allorf_0836062_0836154"
                     /locus_tag="allorf_0836062_0836154"
                     /protein_id="allorf_0836062_0836154"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSKTGTVSGVAEGVRGSLCPGGHSCATAGA"
     CDS_motif       complement(16598..16648)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSKTGTVSGVAEGVRGS"
                     /locus_tag="allorf_0836062_0836154_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16556..16597)
                     /prepeptide="core"
                     /locus_tag="allorf_0836062_0836154_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="1108.2"
                     /monoisotopic_mass="1107.5"
                     /core_sequence="LCPGGHSCATAGA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSKTGTVSGVAEGVRGS"
                     /leader_location="[16597:16648](-)"
     misc_feature    16644..16655
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.57"
                     /tool="antismash"
     gene            16676..17224
                     /locus_tag="MF672_RS34090"
                     /old_locus_tag="MF672_034090"
     CDS             16676..17224
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891842.1"
                     /locus_tag="MF672_RS34090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034090"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_242383234.1"
                     /transl_table=11
                     /translation="MDPVEQLLHPVRLRIVHALAAGRVLTTTQLCARLPDVPKVTLYRQ
                     VALLAEGGFLEVAGERRVRGAVERSYRLRRDRPVIDARAAAGMSLDDHRRGFAAAMAVL
                     IAEFGAYLDREGADPVADSVSYRQGTVWLSPAELKDLLGELLTVLAPRLRQGPGPERAP
                     YLLSAILFPGAPPPEDTGG"
     gene            17334..17732
                     /locus_tag="MF672_RS34095"
                     /old_locus_tag="MF672_034095"
     CDS             17334..17732
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547768.1"
                     /locus_tag="MF672_RS34095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034095"
                     /product="VOC family protein"
                     /protein_id="WP_242383236.1"
                     /transl_table=11
                     /translation="MPHHSRLCRIVIDVEERHHADELAFWQAATGTALTHYAEFPEFHG
                     ALLGSGEFGLLLQRSGEGPARVHLDIHTDDLDAEVARLERLGATRVRHVEDRWWIMRDP
                     AGLPFCVVPEPPGALHEGNAQRWDDQDA"
     gene            17794..18783
                     /locus_tag="MF672_RS51540"
     CDS             17794..18783
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654115.1"
                     /locus_tag="MF672_RS51540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="slipin family protein"
                     /protein_id="WP_302893327.1"
                     /transl_table=11
                     /translation="MDISLVLAVAAFLLFLAAVSGVRVVNQVERGIVFRFGRAQPQVRQ
                     PGLRFLIPVADRMRKVNVQIVTMPIPTQEGITRDNVSVRVDAVVYFKVQDPMRAAIEVQ
                     NYLFAVEQVAQTSLRSIIGKSELDDLLTNREELHKGLALMIDSPALGWGIHIDRVEIKD
                     VQLPEPMKRSMSRQAEAERERRARVIVADGELQAARKLADASAIMSRTSGALQLRLLQT
                     VVEVAAEKNSTLIMPLPVELLRFFDRATPEPAPATASAAEPTTEPTTEPTTGPVTGAES
                     AAQVPPAPDRLALGEPGAGERPALAEPRTAEPRTAEPRTAEPAGPPGP"
     gene            18811..19812
                     /locus_tag="MF672_RS34110"
                     /old_locus_tag="MF672_034110"
     CDS             18811..19812
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017567347.1"
                     /locus_tag="MF672_RS34110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034110"
                     /product="magnesium and cobalt transport protein CorA"
                     /protein_id="WP_242383239.1"
                     /transl_table=11
                     /translation="MRAVIVDKAVYCDGVRETITGDISEAWTAARAKGGGFLWIGLHEP
                     TQEEFDLITSEVELHPLAVEDAIKAHQRPKLERYDHTLFVVLKPLLYVERTSDIEVGEI
                     NLFLGRDFVISVRHGQADPLAGVRRRVESDPELLAAGPAGVLYAICDQVVDTYSVVSHE
                     VEHDLIALERRVFSGEHFDVTADIYSLKREVLEFRTAQDPLIPVLEEIVKGRVELCAST
                     RELFRDVLDHLLRVDGQVDEHNELLTSALSAHLALVGSEQNKVAMQQNADMRKISSWAA
                     LIAVPTMIAGVYGMNFDHMPELHWTFGYPLCLAVMAVAVVVVYRLLRRSGWL"
     misc_feature    complement(18827..18842)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.17"
                     /tool="antismash"
     misc_feature    complement(19872..19885)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.08"
                     /tool="antismash"
     gene            20066..21760
                     /locus_tag="MF672_RS34115"
                     /old_locus_tag="MF672_034115"
     CDS             20066..21760
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547767.1"
                     /locus_tag="MF672_RS34115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034115"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_247815557.1"
                     /transl_table=11
                     /translation="MPRTAPPFRLAVVLAGGVLAAGGLVAVLGSPAAAAPADGAYTLVN
                     AGSGLCASVPGASTADGVQLAQNTCTGTAGQIFTLTTTGAGYRLTAAHSGKCAGVRDAS
                     TSAGKPVQQETCTGATSQTWQLTASGNAYRLVNANGGKCLNVKDNATTTGAPLQQNSCD
                     SVATKQWTLRPAGGTPTTTPTSTPTSTPTATPTVTPTGPASGTLYVAPNGTDAAAGTQS
                     DPTTLTSAITRIAAGGTIYLRGGTYAFAQTVTIAPGNNGTAAARKKLSAYPGETPVLNF
                     SAQSEDPANRGLAVNGSYWHVYGIVVERAGDNGIFVGGSNNIIERTVTRYNRDTGLQLS
                     RIASDTPNSQWPANNLMLSVLSHDNADSDGEDADGFAAKLTVGSGNVFRYAVSRNNIDD
                     GWDLYTKTDTGPIGPVTIEDSLSYNNGTLSDGSQAGNGDRNGFKLGGEDIPVNHVIRRN
                     IAYHNGKHGFTYNRNLGTMTISGNVSIDNTERNFSFDGGTSVFRDNVSCRSGSGSNDKI
                     VGDADSSNQFWTGTNGSRCASYKGALSWSFASDGRLVVTFGGTPVTP"
     gene            complement(22170..22760)
                     /locus_tag="MF672_RS34120"
                     /old_locus_tag="MF672_034120"
     CDS             complement(22170..22760)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020547763.1"
                     /locus_tag="MF672_RS34120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_034120"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_242381104.1"
                     /transl_table=11
                     /translation="MGRWEPNARGRLEEAALELFGERGYEQTTVAEIARRAGLTERTFF
                     RHFADKREVLFGGSTLLHERLTEAVAAAPEPVAPMAAIAAALDVAGVILQERRERARRR
                     QAVVLAHAELRERELIKLASLSAALAGALRERGVPEPAASLAAEAGMAVFRVAFERWAD
                     DPACDADLREVMRATMTELRSVTAGSPTPADPP"
ORIGIN
        1 cgcccagccg tcgcggccca cggcgacggc ggtgcgcagg tagacgtccc tggtcggcag
       61 ggccgggccg agctgcttcc accagtcgag gaacctgggc tgccagccct ccagcgcgcg
      121 ctgcaggcgg cggtcgccgg ccaggttcac gttgttgggg atgcgtgcgc cgtagtccac
      181 gcggctgagc gggcccgcgg gggagggggc cgcgccggtg cgggggtcgg tgctcatcgc
      241 tggctctcct cgcgacgtcg ggtgcgggcc gggcctcccc tcaacatgcc acagtccgct
      301 cgtgtgccgg aagagctgtg tagcgcttct ccgcgctgcc ggggcctgtc ccgggcgccc
      361 gtcagcgggc ggcgcgccac gccgacgggg tggcgccgcg cgcccgcttg aacgccacgc
      421 tgaacgcgaa cgcgtcctgg tagccgaccc ggcgggccac ctcggccacc gtctcccggc
      481 cgtcgcgcag caggtcggcg gcaagggtca tgcgccagtc ggtgagatag ccgagcggcg
      541 gccggcccac caggccggtg aagcgctggg cgaacgcggc gcgcgacagg ccgacctcgc
      601 cggccagcgc ggcgaccgtc caccggcggg ccgggtgctc gtggaggaga cgcagcgcct
      661 cgccgatcgc cgggtcggac aacgcccggt accaggcggg cggcgccgcc tccggccggg
      721 tgcaccaggc ccgcagcgcg atcaccagga tcaggtccag cagccgcgcg aggaccgcgt
      781 cctggccggg ctcgtcgctg gcggcctcgg cggacagcag cccgagcagc gccctggtgc
      841 gcggccccgc cggcaccacc gccagcggcg ggagcaggcc cagcagccgg gcggccacgt
      901 cgccgcgcag gtcgtacacg ccgcgcagca tgaccgtggc acccgctggg ccgcccgctg
      961 tgccggcgcc gtacgtgcgc gggaccggct ccgggcccgt ccactccacc ggcgcgccgc
     1021 ccggcaggaa cttgcgcccg ccgcggatca cgtactgcgg ggccgtcgcc ggatcgtcgg
     1081 tgatcgtgta cccgcccggc gcggtgacca gggcgatgtc accggccgcg agcgccgtgg
     1141 gcggcccgtc gccggcccgg atcgcggccc gcccgcccag cgcggccgcg accgtcagcg
     1201 gcggcgcgtc ggcgtaggtg atgccccagg gcggcggctg cacgagccgg cggaccaggg
     1261 cgttgcgcgc gcgggcccgg ttcagcaggt cggtcaggac gtccaccccg ccaccttaga
     1321 cgctcacaaa ggcatcgcgg actttctccc atggatcgtc cacgcgccga tggggttggc
     1381 tggtcggcat gacgagatcc atcgcagtgt tcggcaccgg accgggcgtc ggccaggccg
     1441 tcgcccggcg ttacggcaag gaggggtacg aggtcgtcct cgtcgcgcgc cgccgggagc
     1501 ctctggaccg gctcgcccgc gacctggccg ccgagggcgt caccgcccac gtgatcaccg
     1561 gcgacctcgg ccgcagcggc gacgtcccgg cgctcgccgc ccaggtccgc gccgccgtgg
     1621 gcgaccccac cgcgttctac tacggccccg tgccgtcggg cctgacgttc gtgcccgccg
     1681 tcgagctcac gcccgggcac ctggcggagc ggctggagat caccctgcac accctgctgg
     1741 ccctggtcgg ggagttcctg ccggcgatgg cggagcgggg cgacggcgcg atactcaccg
     1801 cccagggggc cgccgcggcc cacggccggc cgtacatgag cggctggccg cccgtcctcg
     1861 ccgcccagcg caactacctg cagtcgctcg cggccgaggt cgccgggcag ggcgtgtacg
     1921 tcggcatgct ctacatcggc tcgcgcatcc tcggcacctc cttcgacgac gactaccggc
     1981 gccgccaggc ccgcggcgag cccgtgcccg acctgcccgc cgccgacccc gccgacctgg
     2041 ccgacctcct gtggtcgatg cacgcgcggc gcgaccggca cgagacgatc gtctgaccgg
     2101 cggcccccgc cgcccggcgg cctggcagga tctcctcgtg acgcgaccca cggtgacctt
     2161 gcgcaggatc gagctcgcgg actggcccgc cgtgcacgcc tgggcccgcc tccccgagtc
     2221 ctgccgctac cagacgtggg ggccgaacga cgaggagcag acgcgcgcgt acgtggcggc
     2281 cgccgcaggg gagtggtccc gcacgccgcg acgcgccctc ccctacgcgg cccacgtcga
     2341 cggcgaggtg ctgggcatgg gcaccctgca cctccgcgac gcggcgcacc gccagggcga
     2401 gatcacctac atcgtgcacc cgcgcgcgtg gggccggggc gtggcgaccg ccatcggcgc
     2461 cggcctgctc ggcaccgcct tcgcggagct cggcctgcac cgggtctacg ccacctgcga
     2521 cccccgcaac gccggctcgg cccgggtgct cgccaagctc ggcatgacct gcgagggccg
     2581 gctccgccac accaccctga tcagggacgg ctggcgggac tccgagctgt tcagcatcct
     2641 cgaacacgag tggcgcccgc ccgcgtgaca ccgaaaaccg gtggaccgcg gggcaggcgg
     2701 ctgtcagcat gggggcgatg taccgagcgt aggaacactc cgatcacgac aggggcgggt
     2761 cccgtcacga ggaccccggc ccctggtccg ggccgcccgt cgacgctcgc ccgtccacgg
     2821 gccgcccgcc aacggcgccg ccccgagccg gccgtacggg ccgcggggcc gcgccggccg
     2881 ccgccgcttc cagcggacgc agccgtgatc gtgagccacc gaaggacatc ccatgcaact
     2941 ccacgagtac gcgaaatacg acgccgtcgg cctccgcacc ctgatcgagg ccggcgaggt
     3001 gaccgccggc gaggtcgagg ccgccgcccg ccaggccctc gaccaggtga acccgcacgt
     3061 caacggcctg gccctgccgc cgttccagcc ggcgctcggc cacgcagggg acggcccgct
     3121 caccggcgtg ccgttcctga tcaaggatca cgggccggtc gccgagggcg tcccgttctc
     3181 gctcggcagc cgcgccctgc ccggcatccc cgcctggcgc gacaccgacc tgatgactcg
     3241 cttccgcgcc gccggcctgg tcaccctggg cctgaccacg gtgccggagc tgtgcgtcag
     3301 cttctccacc gaacccctcc gccacggccc cgcccgcaac ccctggaacc ccggcagggg
     3361 cgtcggcggg tcgagcggcg gcgcggccgc cctggtggcg gccggcgcgg tgccggtcgc
     3421 gcacgccagc gacggcgccg gctccatccg gatcccggcg tcctgctgcg ggctggtcgg
     3481 gctcaagccg agccggggcc gggtcccgtg cgggccggac gcgggcgagc cgatgctcgg
     3541 gatggcgtac gagttcgcgc tgacccgcac cgtccgcgac gccgcccgcc tcctggacgc
     3601 cgtgcacggg ccgggcgtcg gcgacaagta caccgcgccg ccgccgcgcg gcccgtacgc
     3661 cgccgaggtc ggccgcgacc ccggccggct gcgggtcgcg gtgaccacgg agagctgggc
     3721 cggcacggcg gtcgacgccg aggtcgcggc ggcggccgtc cgcgccgggc aggcgctgga
     3781 gcgggcggga cacctcgtca ccaccgccgg gccggccgtc gtctgggacg acgtcgtccg
     3841 cgcctgggtg tgcgagagcg tcgcgatcgc ctcgacgctg ctgctggccc cccgccggcc
     3901 cgacgagggg ctgatggagg ccgtctcgcg gcagttcctc aagacggccg aggagtacag
     3961 cgcgctcgac atgctggccg ccttcgacgc ccagaaccgg gtgtcccgcg cggtcggcgc
     4021 cttcttcacc ggctacgacc tgctcgtcac ccccacgctg ggacggctgc cggcgccgca
     4081 cggcgtcctg cgctacgacg acccggagca gacgctgacc ggctggctgg ccgcgctcac
     4141 cgagtacggg ccgttcacgc aggtgttcaa cgtgacgggc ggcccggcga tcagcctgcc
     4201 gctcgggcac agcgaggacg ggctgccgat cggcgtgcag ctcgccgccg gctacggccg
     4261 ggaggacctg ctcctccagg tggccgccca cctggaggag gccctgccgt ggcgggaccg
     4321 cgtcccgccg atccacgccg gcggccgctg acccgccaga gcccggggac acgaacgccc
     4381 gggcccctcc ggggacacga acgcccgggc ccccgccggg ggcccgggcg ccgcgcggcc
     4441 ccggcgacgg tcagtcgctg gtgacggcgt cgagcaggtc gctgacggtg gcgtcgggca
     4501 gcgcccgggc cacctcggcc agcgcgacca tgccgacgag gctgtgcccg tcgatgacgg
     4561 gcagccggcg caccttgtgg ccggccatgg tgcgcaggat ctcccgcgcg tcgtcgtcgg
     4621 cgccgatcgt gaccgcctcg ccctgggcga gctcgcccgc cacggtcttg gccgggtcct
     4681 tgcccgcggc caggaccttc acgacgatgt cgcggtcggt gagcatgccc ttgagccggt
     4741 tgtcggtgcc gcagatcggc agcgagccga cgtccaggcg ggccatcttc tcggcggcga
     4801 cgagcacggg ctcgtcggcg ttcacgcact cggcgtccgg ggtcatgatc tctcgtgcgg
     4861 tcggcatgac gctcctcatc gaatgtcggg gtcagtgccg actgcccccc tgaggcgcgg
     4921 tgaaacgggg ccccgcggcc gggccccgcg gcggggcgcc gcccggcggg ccggtcagcg
     4981 ggcgacggcc tccagcaggt gcacgtcgag cggcaggccg gcgcgggagg tgagcgcgaa
     5041 cccggcggcg gccagcagct cgcggtactc ctccagggtg cgctcgcgcc cgccggcgtt
     5101 gttgaccatc atgtggacgt cccacgcggc ggccagcgac ggctccccgg cccgctcggg
     5161 cagcagccgc tcgacgaccg cgagccgccc gcccggccgg gtcgcctccc ggcagcgggc
     5221 gaggatgcgg gcgcaggcgg cgtcgtccca gtcgtgcagg acgcgcgaga gcacgagcag
     5281 gtcaccgccc ggcacccggg agaacaggtc gccgcccacc gcgctgaccc ggccgccgtg
     5341 ccgggccacc agggcgggcc gcgcggccgc gaccgtcgcg ggcgtgtcga acagcacccc
     5401 cgtcacgtgg ggcgcggcgt ccaggaggcg gccgagcagc gcgccggtgc cgccgccgag
     5461 gtcggtgacg gtgccgacgc cgtcgaggtc gagccggtcg gcgaccgcgt cgaagacgtc
     5521 gcggcactgg tcggacatgg cgagctggaa gaccgccgcg tcgccggggc aggcgtcgag
     5581 gtgcgcgaag ggcgcgagcc cgtaggccag ctcgaacccg ctcggcgcgg cgccgcgcac
     5641 cgcgccgggc agctcgccga agctgcggta gaacagcccg ccgtacagca gtgcgacgcc
     5701 gtgcagcgag gagggggagt cgcgggccag cgtcgtgccc agcggggtca gcgcgtacgc
     5761 ctcgccggcg cggcgcacga cgccgagctg ttcgaggtag cgcagcagcc ggccgagccg
     5821 gtcggccggg caggcggtgg cgcgggccag ctcgccgagg gtgcggtcgc gggcgtgcag
     5881 caggtcggcg acgccgagct cggcggcggt ccgcagcgcc tgggtggtcc acgcgccggt
     5941 gagcaggccg agcatgtgcc gccgctcctc gggggcgccg aggtggcggg ccagctcggc
     6001 gcgggcctgc ccggccgcga cgatctccag ccggtcgccg ccccgccgcc ggaagtagaa
     6061 cacgctgcgc ccggaggggc cctcgccggg gttgaagccg ccgccgtcgg gcaggcagcc
     6121 gtcggcgcgc agcgcctcca gcacgccgag ggacgcggcg ggcgcctcgt acgccaggtg
     6181 cgtctcgcgt tcgtgcagcc gctcgtcgcc ggccacctcc ggcgggcagc cggtcgcgag
     6241 gaacagctcc agcgtccgcc cgccgccggc gtcgaggtgg gcgatggtga cctcggggcc
     6301 ggcgaggccg tagcgccggg ccagccgctc cttgacgatc acgctgggca gcctcctgac
     6361 cacgggcagc ccggccagcg ccgcctcggc cgagcgcggg aacaccagca gccccgcgtg
     6421 gtcgaagcgc agcccgtacg gcccgtcgcc gccgtcgcgc gccacctggg ccatcctgcc
     6481 gagccgcgcg gcgtcggcct catccagcgc gccggacgcg atctccggcg acagcacgtt
     6541 cccctgatcc accggcacag gctaacagca ctgcccgtag tcgatggacc gctctgcgta
     6601 acgtcagggg cggtggaccc cgggacgcgt cccggccggg gcgggggaga agagaggggc
     6661 gggcagcagc ttgccgaagg ggaccgcgcg caggacgcgc agccgctccc cggcggccgg
     6721 atggccgtgc tcggcggcca gccggtagta gaagcgggcg atgaccagct tggccgggcc
     6781 ctcctcctcg tacgcctgcc cgagggcgaa ggccagctcc gccgccagct cggccgggcg
     6841 cgggtgggcc gccagcgcct cggcgtgcgg gtggcggtga cgggccgcga cgtgcagcca
     6901 gtagccggcg gccgagcggt cgccggtgag cagggcgatg atcgccagcc ggcaggcggc
     6961 gtcagggtcg ccgtcgcccg ccagccgcat cagccggtcg acggtcctgg tggtgcgccg
     7021 ctcggcctcg tcggcgggcg tcctgaacag gtcgtgtgag ccggtgaccc gcggccgggc
     7081 cggctgctcg ctgcgggcgg cgcgccagcg ggcctgccac tgctccaccg tgccgagggc
     7141 gtccgtgggc aggccggtca gctcggcgtg gcggtggcag accttcacga aggaggcgac
     7201 cagcccccag tcgggcaggc gctcccgctt gccggtgagg atgtcgttga ccgtgctcgc
     7261 cggcagctcc ttgggcacgc ccggcgcgcg cgacaactgg tgcatcgtcg agtagctcgg
     7321 ctggccggcg gcttcccgca gccccacgag cgcggctatg aaggcgggat gggatccggc
     7381 ccggtaggtg tcagtcatcg tccttggttg gatcgaatgg tcatgatggc ggccatattt
     7441 tcagagaatg tctcgcggtc gatgacactt cgcggattcc atctcgtccg gtcgccgtgg
     7501 tcacggggcc tgtcagacgt cgcaggagtc ccagaggcgt gcgacgcgct tccgcccgga
     7561 cggatccgga cggaagcgga ggaaaccgga ggagaccgga ggagaccgga ggcccacccg
     7621 ccgggcgcgg gcgctccggt gtcgtccggc ctcctccgag cccgggcgga ccggtggccg
     7681 gcggcccgcg cgcggcggca gcgtggggcg cgatccaccg cccctcccgg aaggccgccg
     7741 ccccatgccg ctgctcacgg cccgcccgtc cagcatggcc taccgctctg acgcgccctg
     7801 cccggccgac gagcacctgc tggtcacgct cgtgacgacg tgggtgctgg cgacgggacg
     7861 ccggccgccc gccgcccgcc cgggcgacct cacggccgag gagctgatcg agttctgggc
     7921 ggacgaccgt ctgtgaagca tcgagaaaga ggacccatgt tcaccacccg gcagttgctc
     7981 acgctcacca tggcgctcac cgtcgccgcc atcacctgcg cgctcgtgct ggccggcggc
     8041 gtcgcgtggc cgggcgccct gctcagcggc gggggcgcgg gcggggcgac gctcgccgcc
     8101 ctgccgaggc tgctgaccag gcgcgacccc cacccctgac cggccggcga gggtcaggcg
     8161 ggggcgtaca tgcgggcctg gagcccgtac agctcggcgt accggccgcc ggcggcgatc
     8221 agctcgtcgt ggctgccgtg ctcggccacc acgccctcgt gcagcaggta gatgtggtcg
     8281 gcgttcctgg cgctggccag ccggtgcgtg atcagcacga cgacgcggcc ggcggcgagc
     8341 ccgcgcagcg actcgtacag ggcgaactcg gcgcgcgggt ccagcggcgc ggccggctcg
     8401 tcccagacga tcagaggggt gtcgcggaac aggccgcggg cgatggccag gcgctgccac
     8461 tgcccgcccg acagctcgtg cccgccgtgg aacgccttcg acagcagcgt ctcccagccc
     8521 gacggcagcc cggccaccac cgcgtccgcc cccgacagcc gggcggcggc ctcgagcgcc
     8581 aggtcgccgg ggtcgggccg gtcgtgccgc ccggcccgca cgttgacccg ggcggtgtgc
     8641 ggccagcgga ccggggcctg cggcacgagg gtgatccggt cggcgacgtc gcgcgggtcc
     8701 agctcggcga ggtccacgcc gtcccagcgg accgagcccc ggccgggcgc gtacagcccg
     8761 gcgaggatct tggcgagggt ggacttgccc gagccgttct cgccgaccag cgcgaccgtc
     8821 cggcccgccc gcgccgtcag cgacaccccg cgcagcgcgg gccggtcgcc gcccgggtag
     8881 cggaagcaca cgtcccgcac ctcgaccagc tccggccggg cgggcgccgg acgggtgccg
     8941 ccggcggccg tcctggtccg ggactcggcc acgaaccgct ggtagtcgcg gacgtacagg
     9001 ccctgctcca ggagctggtt ggcggcgagg acgagcctgc tcagcgacgc cgagccggtg
     9061 cgcacggcca tcaccgccgc cccggccacc gccagcggga tccagcccgc ctgcagcagc
     9121 ccgccgagcg cggcgaacgt caggccggtg ccgaggccgc tcagcgcccg gccggccgcc
     9181 cgcacccgca cctgcgcgac cgccaccccc acctcctggt cgcgcagcgc gtcggccacc
     9241 gccccgtact cgcgcagcag gaacccctcc gcctggcagg cccggatctc ggcggccggc
     9301 tcgcgcccca tcgccaggtc cgtcagcatg cgcacccgcc ggttcagcgt gacggtcctg
     9361 gtcatgaacc ggtacgccag ccgcgtggag cgctgcaccg accagccgct cggcagcacc
     9421 acgaccagca gcaccgccag cagcgccgga tgcagcacgg ccacggcgac cagcgccgcc
     9481 ccgaccgcga gcgccgcgct gaccagctcg accgcgttgt ccacggcccg gcccaggtgg
     9541 aacagggcgc ggtcgcgggc ccgctgcatc cggtcgaaga agtcggggtc gtcgaaggcg
     9601 gccagctcca cccgcagggc cgcggcgaac agctcgccct ccgcgacccg ccgcaccgcg
     9661 ggcggcaccc gggcgtgcgc cgcggcggtg gccgccccca ccgcgccgcg cagcgcgtac
     9721 gcgcccgcca ccagccccat cgcgggcagc gccgtcacca ggtcggcgct cagcagccgc
     9781 tccagcgcgc ccgccgtggc cagcagcccg cacgcggtgg cggcggccga gacgacctcc
     9841 agcgcgagca ccagcgcggc gtgccggggc gaggcgcgcg cgacgaccgc gagcaccgcc
     9901 ccggccgtcg cgggcaggcg gccgatcatc cgccgcagcc cgaggtcggt ctcgggctcg
     9961 tcgagccgcc agtacggccg gaccagctcc ccgtccgccg tcaccgccgc cccccgccca
    10021 cccgctcacc cgggaccggc cgggcgccgt ccagcaggga gccggacggc aggtccgggt
    10081 ccgggagcag caccgacggc agggggcagc ccgggtgcat gcgcaggagc tggtaggcca
    10141 ccccgccgag cccgggcagc agccccgggc agaacgcctc cctggcgaac ccgctgaccg
    10201 gcccgtgctc ctccaggctg ccgagcgtgt gcgcgtccag gatgtcgcgg gtcatgcccg
    10261 gctcggcgac gcccgccgcg agcgccaggt cgatcacctc ccacgcgccg aggtcgccgt
    10321 ggcacaacgt gtggttccag cccatgccgc ccgccttggc ggcggccgcc gcgcggcgca
    10381 gcacgtcgag ccaccgctcc gggtcgccgc cgtgccgcag ccggtcggcc gcgacgacgc
    10441 cgatcccggc cgcgccgtgg caccacgccg ccgccgtgat gtccggctgg cgcaggtcgc
    10501 gccagctccc ggcggagggc acgtacaggg tctcctcgta ggcgaaggcg gcctcggcga
    10561 cctcggtgaa gtcgcggtcg ccggtggccg cgccgagccg ggcgagcgcc cagccgatgc
    10621 cggtcgcgcc gtgcgccacg ccgcccagcc cgctggggaa gaactcgctg tcccaccagg
    10681 cggtgccgtc ccgcagccgg gccgccgcca cgagccgccg cccgatccgc accgccaggc
    10741 cggcggccgc cgggtcgtcc agcgcgagca gcggcaccac catcccggac aggccgctca
    10801 ccaggtcgag cgcctgctcg tccgggacga gctcgtccgg gacgagcttg gcggcgcgct
    10861 cgcgggcctc ctcgtcgccg acgacgccga gccgccgcag cagccgccag ccccacacgc
    10921 gcgagcccag ccccaggtag ccgccggcgg gcgggggccg ccgccgcgtg gtcagctcga
    10981 cggtcgcctg gtcctcggcc ttcctcatcg tccgcagcac gtcggccagc agcgacggca
    11041 cgcccggcac cgggtcggcg cggccgtgcc cggtctcgtg ctcgtacgcc gccagcagca
    11101 ccgccacgcc ggtgagcccg ccgtacaggt cgggcccgag cggcagcacg gcccagccgg
    11161 tcgggttgag caccggcgcg atccacgtcg ccgtgccgtc ctcggcccgg atcgcggacg
    11221 ccaccaggtc gccgacgatc ttcgcggcga ccgcgcggcg gcgccggtcc agccgggtca
    11281 ggtcgcggcc ggagggcagc agcgcgcggt ggtcgggcag ccagccctcg ttcaggtacg
    11341 cgctgaccag cgtcgactgg atcacccgcc ggtccagccc caggtcggcg ctccgccagc
    11401 ggcccagcgc cgccgcgacg aggtcctgct ccggccccca ggaggtgccg cgcggcccgg
    11461 tcagccgccc cacccgcggc gtcgtgctga agaacggcac gtcgctgtcg agcagctcgg
    11521 cgacctcggc ctcgatgacg gcggggtcgt cggggcggcc gggcaggttc cgcgactgcc
    11581 gggtcagcag gctcacggcc ttggcgcggg cggccggctc gtcgtgcagc gcgtgcgggt
    11641 gccacaacat gcgggccagc tccgcgtacg tctcggtgga cctggccacc acccggacgg
    11701 gcaggccggc gaacccggcc agcagcggct ccagctcgcc ccgccggtcc aggtcgcgca
    11761 gccggtcgct cagctcggtg aacccggcca cgatccggtc ccagtacgcg cccagcaccg
    11821 gatcagggct cggatggttg accgcggccc ggatcggcgt ctcggcctgg ccgatgcgcg
    11881 cctcgtcggt gccggcgtcc aggatgacgg gcagcttcgg cgccggctgc tggccgggca
    11941 gcgcgccgat ggccgacatg tccacgccgc gccagccgag cgccagcccg cggcccggca
    12001 gcaggccggt gcccagcacc gagccgccca ccagccgcga cgcgcggtcc accgccagcc
    12061 cgtacgccga gtcgggcatg ggcggctgcg gggtgaacaa cgtctcgcag tccaccaccg
    12121 tcgggacggg gccgcacgcg atgacgttct cggcgtgcag gtcgctgccg ccgatcaggc
    12181 gcatgaccgc cagccagtgg ccgaggttgc ggtagaaggc gcgcagctcc tcctcgccgg
    12241 cgcagtagcg gtgggcgacg tgctcggccc agccgtaccc gtcgccggtc accacccggg
    12301 gcacgctgat ccgccagggg tcgtccccga gcacggcggc gaggaaccgg gacagggcca
    12361 cgtccacggc catcgagcgc ggcttgtaga ccagcagccc gccggagagg cgcagcacgg
    12421 cgacggtccg cccgccgcgg tggctgtcgc ccgccccgaa cgcgacaccc cgcagctcac
    12481 cggcccgcag ctcaccggcc cgcagctcgc cgccctgctc accgccctgc tcgccgaccc
    12541 gctcgccgct cgtcagggcg ccgagcttgt cgcggtcggc ggcgaagcgc ctggccagct
    12601 ccagcgccgc cgcgcaccgg ttgccgacca cccggtccag ccgggggcgc agcgtcgggt
    12661 agtgcccggc cagcccgtcc cagaactcgg gcgtggccgc gccctcctcc cattcccgcc
    12721 accgggcccg cgcgtcggcg ccggtgagcc tgccgctgat ccgggccgcg ttcagctcca
    12781 ggagcaggac gcggttggtg cgcaggcggg ccgcgtgcag cgcggacgcc tccgccgcgg
    12841 agcgcagcac cagccgctcc gcctccgtca ggccgtcgac ggcgtcgagc tgggccgcga
    12901 gcccggccag ggccggttcg agcaggcagc ccagcacgac gtcgctcacc gcgttggcgt
    12961 gcatctggtc agcagcactc gagcccggcc gaccaggtgc aggctgtgcc gcagtgcccc
    13021 gactccgggg gcggcgggca gccgaccccg gtgcagccgg aggcggcgaa gatggactcc
    13081 atcgtgatgt cggcctcggc gtactcgccg ccggcgaaca gcgggccggc cgggttgtcc
    13141 cagccgtcca cggtgtcggc gccgctgcgc cagccggcca cgatgcgttc ggcgagttcg
    13201 gcggtcatcc tggacatgac gtcatcccct cctcgaaagg gtttgggttg gacgtccgga
    13261 ttgtggcaac cgccgttgcg caatccgttg cagccgggac ggccgcccgc gccctcagga
    13321 gccggtcccg gccggctcca gcacccggtc cacggcgctc agcgccagcg tcttgtagcc
    13381 gaccgagtcg aacagcacgg tgatccggtc gggctcgcgg ctcatgaccg tgccctcgcc
    13441 ccacgtcttg tgccgcacct tcgcctggac ggcgaacggc ccctcctcgg ccggggcggc
    13501 ggccggctcg ggccgcgcgg ccgcgccgtc gcggcaggag tcgcacgcgc cgcacgccgg
    13561 ggcggcgtac ggctccccga agtaggccag caggtaccgg cggcggcagc ccctggtctc
    13621 ggcgtagccg cgcatcatgt cgagccgcga ccggtccagg tggtggcggg cctcgtccag
    13681 cccggccgcg cgctcggcgg cgcgctccgg cggcagcgcc gggtcggcgt aacggagggc
    13741 gcccgcgtcg gtgacggcca gcgcccccgc ccgctccagc aggttgacga gcctggtgag
    13801 ctgggacgcg ctcagctcca gcagcccggc cagctcgcgc gccggcacct ccccggcgtg
    13861 cccgcgcacc agcgtcgcca cccgcagcag cgtcgcggcg tcggcccggc cgccggtgaa
    13921 gaagcggcgc agccccaggt cctccggccg gtagaacagc acggccgtgg cgggcgcgcc
    13981 gtcgcggccg gcccggccga tctcctggta gtaggcgtcg ggcgactccg gcggggcggc
    14041 gtgcagcacc cagcgcacgt cgggccggtc gatgcccatc ccgaacgccg acgtcgcgac
    14101 caccacgtcc aggtcgcccg aggtgaacag ctcctggacg cgggcgcgtt cggcggcccg
    14161 catcccgccg tggtacgcct cggcccggcg gccccgctcc gccagcgcgg ccgcgtaccg
    14221 ctcggtgtcc ttgcgggtgg cgacgtacac caggccgagg ccgtcccggg cggcggcgtc
    14281 ctcggccagc gcccggctct tgtcctcctc gcggacgaag cggcgcacct ccagcgcgat
    14341 gttcggccgg tcgaagcccc tgacgatctc cacggggtcg cgcaggccga gcgcccggac
    14401 gatctcctcg cgcacgttcg gcgcggcggt ggccgtcatc gccaccaccg gcgggtgccc
    14461 gagccgcgcg atgaccttgc cgagccgctg gtagtcgggg cggaagtcgt gcccccaggc
    14521 cgcgacgcag tgcgcctcgt cgacggcgac cagcgacggc cgggccgccg ccagccgctc
    14581 gaccacctcg ggcttggcca gctgctcggg agagaggaac acgaactccg ccgcccccgc
    14641 cgtcacctgc tccaggccgc tgtccacgga cgtggtcgag ttcaccgcca ccgcgccgcc
    14701 cgcgtccgcc ctgagcagcc ccgccacctg gtcgcgctgg agcgcgatga gcggcgagac
    14761 gacgaccgtg ggcccgtcga ggagctgcgc ggggatctgg tagaccgccg acttcccggc
    14821 gccggtcggc atgacgagca gcacgtcacg cccggcgagc aggtgctcca tcgcctcctg
    14881 ctggcccggc cgcagccgct gccagccgaa ccgccggcgc gccgtggccc gcagccgccg
    14941 gccgcgccac ccgaaccggt gcctcaacgc cgtccctaac cccacctgcc gcccgccctt
    15001 cgtccgtctc cctgtcgaag tggccgggcc agtacccagc cgggccccgc ccatgcgcca
    15061 cttcttccga tcatgagggg ataccttgac ccgcgtcccg ttggcggggc gccggggcag
    15121 gcaaggaacc gttcatggac gagcatccgc cgcgcacccc gaccaccgcc gacggccggc
    15181 tcggccgcgc cgccgaccat cccgggatgc gcgacccgcg ctacctggcg cggcggcgct
    15241 ggttcgcgca gctggcgcgc gggcaccggg tgggcgaccc ggcgccgcgc gtggagtacc
    15301 ggccgggcga gcacgcggtc tggcgggcgg tccggcgggc cctggaggac gcgcaccgcg
    15361 cgcacgcctg ccgcgaggtg ctgtccgccc gcgaggccgt gcgcttcccc gccgaccgcc
    15421 tcccgcagca cgccgaggtg ggggcgcagc tgcggcggct gaccggcttc gacttcacgc
    15481 tggccggcgg cgtggtggcc aacgagcgct tcctcggctc gatggcccgc gggtacttcc
    15541 acgcggtgca gttcgtccgg catccggcgg tgccgatgta cacgccggag ccggacctca
    15601 tccacgacgt cttcggccac ggcatccacc tggccgcgcc ggtcttcgcc gccgtctacc
    15661 ggctgatcgg cgaggccgcg gcgcggctgc gcaccgggca cgcgctgcag atcgtcagcg
    15721 acctgtactg gtacacgctg gagtacggcg tggtggagga cggcggcgcg accaaggcgt
    15781 acggggcggc gctgctgtcc tcctacggcg agctcggccg cttccgcgcc gccgacgtgc
    15841 gcgagctgga cgtgccggcg gtgctcgcga cgccctacga catcgcgggc taccagccgg
    15901 tgctgttccg cgcccgcagc ctggcgcacg tcgccgacac gctcgcggcc ttcctcggcg
    15961 ggctggacga cgacaccgcg ctcgccgcgc gcccgcccgc cgcgccgtga cccgccgtga
    16021 cggggcggcg ggggctccgc cggcccccaa gaccggcgag tccgcgccgc ccgccgcagc
    16081 aggggagcgg gcagatcagc aggtcggcgc gacggcgtcg atcttgccgc cgaagtcgtt
    16141 gtcgtacacg ctgcggtagt cgccgtcgcg gacgacgcgg gtctccttgc ggttgggcac
    16201 ctggatccag ttgatgaagc agccgttggc gcccgcgcgg aaggaggcca cgttgtcgtg
    16261 cagggcgggc ggcacgtcca cgtacccgtt gcccggattc cagcaccagg acgcccccgt
    16321 gtagttccgc ccgctgtaga ggcagatgtc gcccgcccgc gcggccgcgg cggcgggggc
    16381 cgagcacagg gtcagcgcgg cgagcgcggc ggcggaggcg gcggcgatcc gggtgacgtg
    16441 cgtcgtcctc atggcggttc tcctcgtcat cgatgcccgg gcggcggacg ccgtccggct
    16501 cggtcacatc ctgtagcaga tcgtgcacgc ttcgaatccg ccgcagtgga agagatcagg
    16561 cacccgcggt ggcacaggag tggccgccgg gacatagcga gccccggacg ccttccgcta
    16621 cgccactgac cgttcccgtt ttggacaacg gtatcgctcg tgaaatcgtc gccgtatgga
    16681 ccctgtcgag cagttgctgc acccggtgcg gctgcgcatc gtgcacgccc tggccgcggg
    16741 ccgcgtcctg accaccacgc agctctgcgc ccgcctgccc gacgtgccca aggtgacgct
    16801 ctaccgccag gtcgcgctgc tcgccgaagg cggcttcctg gaggtggcgg gcgagcggcg
    16861 ggtacgcggc gccgtcgagc gcagctaccg cctgcgccgg gaccggcccg tcatcgacgc
    16921 ccgcgccgcc gccggcatgt cgctcgacga ccaccgccgg ggcttcgccg ccgccatggc
    16981 cgtgctcatc gccgagttcg gcgcctacct cgaccgcgag ggcgccgacc cggtcgccga
    17041 ctcggtgtcc taccggcagg gcaccgtctg gctcagcccc gccgagctca aggacctgct
    17101 cggcgaactg ctcacggtcc tcgcgccccg cctccgtcag ggccccggcc cggaacgggc
    17161 gccgtacctg ctcagcgcga tcctgttccc cggcgcgccg ccaccggagg acaccggcgg
    17221 ctgacccgcg ccgccccctc gttgccctcg ccccgtcctg cccgtacggt acggcgcggg
    17281 gcggtcccgc gtgctcgccc ccgtacccgc ccggacagca ggagaggaca cccgtgccgc
    17341 accacagcag gctctgccgg atcgtgatcg acgtcgagga gcgccaccac gccgacgagc
    17401 tggccttctg gcaggccgcg accggcaccg cgctgacgca ctacgccgag ttccccgagt
    17461 tccacggcgc cctgctgggc agcggcgagt tcgggctgct gctccagcgc tcaggcgaag
    17521 ggccggcccg ggtgcacctc gacatccaca ccgacgacct cgacgccgag gtggccaggc
    17581 tggagcggct gggcgccacc cgggtccgcc acgtggagga ccgctggtgg atcatgcggg
    17641 acccggcggg cctgccgttc tgcgtcgtcc ccgagccgcc gggcgccctc cacgagggca
    17701 acgcccagcg ctgggacgac caggacgcct gacgcgcgca ccgggacggc gggcggcggc
    17761 gggcctatgc tcgggggcgg aagggaaacg cccatggaca tcagcctcgt gctcgcagtc
    17821 gccgccttcc tcctcttcct ggccgcggtc agcggggtcc gggtggtcaa ccaggtcgaa
    17881 cgcggcatcg tcttccgctt cggccgggca cagccgcagg tccggcagcc gggcctgcgc
    17941 ttcctcatcc ccgtcgccga ccgcatgcgg aaggtcaacg tccagatcgt cacgatgccc
    18001 atcccgaccc aggagggcat cacccgcgac aacgtctcgg tacgggtgga cgcggtcgtc
    18061 tacttcaagg tccaggaccc gatgcgggcc gcgatcgagg tgcagaacta cctgttcgcc
    18121 gtcgaacagg tcgcgcagac gtcgctgcgc tccatcatcg gcaagagcga gctggacgac
    18181 ctgctcacca accgcgagga gctgcacaag ggcctcgccc tcatgatcga cagcccggcg
    18241 ctcggctggg gcatccacat cgaccgggtc gagatcaagg acgtccagct gcccgagccg
    18301 atgaagcggt cgatgtcccg gcaggccgag gccgagcgcg agcgccgcgc ccgggtgatc
    18361 gtcgccgacg gcgagctgca ggccgcccgc aagctcgccg acgcctcggc catcatgtcg
    18421 cggacctcgg gggcgctgca gctccgcctg ctgcagacgg tggtggaggt ggccgccgag
    18481 aagaactcga cgctgatcat gccgctgccg gtcgagctcc tccgcttctt cgaccgcgcc
    18541 acccccgaac ccgcccccgc caccgcgtcc gccgctgagc ccactaccga gcccactacc
    18601 gagcccacca ccgggcctgt caccggagcc gagtcggccg ctcaggtccc gcccgcccct
    18661 gaccggctcg cgctggggga gccgggagcg ggcgagcggc ccgccctcgc cgagccccgt
    18721 accgccgaac cccgtaccgc cgagccccgt accgccgagc ccgctgggcc gccgggtccg
    18781 tgaccctcgc gggggcgcgg ctgcgcgaca atgcgtgctg tgattgtgga caaggcggtc
    18841 tactgcgacg gcgtgcgcga gaccatcacc ggcgacatca gcgaagcctg gacggcggcg
    18901 cgcgccaagg gcggcggctt cctgtggatc ggcctgcacg agcccaccca ggaggagttc
    18961 gacctgatca ccagcgaggt ggagctgcac ccgctggcgg tcgaggacgc catcaaggcc
    19021 caccagcggc ccaagctcga acgctacgac cacaccctgt tcgtggtgct caaacccctc
    19081 ctgtacgtcg agcggacctc cgacatcgag gtcggcgaga tcaacctgtt cctcggtcgc
    19141 gacttcgtca tcagcgtccg gcacggccag gccgacccgc tggcgggggt gcggaggcgc
    19201 gtcgagtccg accccgagct gctggccgcc ggcccggcgg gcgtgctgta cgccatctgc
    19261 gaccaggtcg tcgacaccta ctccgtggtc tcgcacgagg tcgagcacga cctcatcgcg
    19321 ctggagcgcc gggtgttcag cggcgagcac ttcgacgtca ccgccgacat ctactcgctc
    19381 aagcgggagg tgctggagtt ccgcaccgcg caggacccgc tcatcccggt gctcgaggag
    19441 atcgtcaagg gccgggtgga gctgtgcgcg agcacgcggg agctgttccg tgacgtgctg
    19501 gaccacctgc tgcgggtgga cggccaggtc gacgagcaca acgagctgct caccagcgcg
    19561 ctgagcgccc acctggccct ggtcggcagc gagcagaaca aggtcgcgat gcagcagaac
    19621 gccgacatgc gcaagatctc ctcctgggcg gccctcatcg ccgtccccac catgatcgcc
    19681 ggcgtgtacg gcatgaactt cgaccacatg cccgagctgc actggacgtt cggttacccc
    19741 ctctgcctgg cggtgatggc cgtcgccgtg gtcgtcgtgt accggctgct gcggaggagc
    19801 ggctggctct gagcgggccg cgcccgcccg gcaccagggc ggtgccctgc gactgcaaat
    19861 cctgcaatcg gttgttgcag aaatagtgat gccaccagcc agaacgtcca ccgtcgtttg
    19921 cagttttacc gggacgtatt gacgtttcgt ccaggtaacg tcactgtgct tgcaaccggt
    19981 tggcgtccgg tccggccctt ccccccttcc tgagcccctg gctcggcagc gccatgcccg
    20041 gacaacgcaa cgaacgaagt tcgacgtgcc cagaacagct ccacccttcc ggctcgcggt
    20101 cgtgctggcc ggtggtgtgc tggccgcggg cggcctggtc gccgtgctcg gcagccccgc
    20161 cgccgccgca cccgccgacg gcgcctacac cctggtcaac gccggcagcg gcctgtgcgc
    20221 gagcgtgccc ggcgccagca ccgccgacgg cgtgcaactg gcccagaaca cctgcaccgg
    20281 caccgccggc cagatcttca ccctcaccac caccggcgcc ggctaccgcc tcaccgccgc
    20341 ccacagcggc aaatgcgccg gcgtccgcga cgcctccacc agcgccggca aacccgtcca
    20401 gcaggaaacc tgcaccggcg ccacctccca gacctggcaa ctgaccgcct ccggcaacgc
    20461 ctaccgcctc gtcaacgcca acggcggcaa atgcctcaac gtcaaggaca acgccaccac
    20521 caccggagcc ccgctccagc agaactcctg cgactccgtc gccaccaagc aatggaccct
    20581 gcgccccgcc ggcggcaccc ccaccaccac cccgacctcg accccgacct cgaccccgac
    20641 cgccaccccc accgtcaccc cgaccggccc ggcgagcggc accctgtacg tcgcccccaa
    20701 cggcaccgac gccgccgccg gcacgcagtc ggacccgacg acgctcacct cggcgatcac
    20761 ccggatcgcc gccggcggca ccatctacct gcgcggcggc acgtacgcct tcgcgcagac
    20821 ggtcaccatc gcccccggca acaacggcac cgccgccgcc cgcaagaagc tgtccgccta
    20881 ccccggcgag acccccgttc tgaacttctc cgcgcagagc gaggacccgg ccaaccgggg
    20941 cctggcggtg aacggctcgt actggcacgt gtacggcatc gtcgtcgagc gcgccggcga
    21001 caacggcatc ttcgtcggcg gcagcaacaa catcatcgag cgcaccgtca cccgctacaa
    21061 ccgggacacg ggcctgcagc tctcacgcat cgcctccgac accccgaaca gccagtggcc
    21121 ggccaacaac ctcatgctga gcgtgctctc gcacgacaac gccgactccg acggggagga
    21181 cgccgacggc ttcgccgcca agctcaccgt cggctccggc aacgtcttcc gctacgccgt
    21241 ctcccgcaac aacatcgacg acggctggga cctctacacc aagaccgaca ccggccccat
    21301 cggcccggtg acgatcgagg actcgctgtc gtacaacaac ggcacgctga gcgacggcag
    21361 ccaggccggc aacggcgacc gcaacggctt caagctcggc ggcgaggaca tcccggtcaa
    21421 ccacgtcatc cggcgcaaca tcgcctacca caacggcaag cacggcttca cctacaaccg
    21481 caacctcggc acgatgacga tcagcggcaa cgtctcgatc gacaacaccg agcgcaactt
    21541 ctccttcgac ggcggcacct cggtgttccg cgacaacgtc tcctgccgca gcggcagcgg
    21601 cagcaacgac aagatcgtcg gtgacgccga cagctcgaac cagttctgga ccggcaccaa
    21661 cggctcccgg tgcgcctcct acaagggcgc gctgagctgg tcgttcgcct ccgacggccg
    21721 cctggtcgtg accttcggcg gcaccccggt aacgccgtga cccctgcccg ccgcccgcac
    21781 tgacccccac caccgcccga ccacaccgat cgggcggtgg tggtcgttcg ggcggtgtcg
    21841 gtcgttcggg cggtgtcggt cgttcgggcg ggtcgcccgt tcgggcggct cggccggtcg
    21901 gggggtgtgg gtcccgtcgg gcggtgtgga tcggcccgcg tggatcggtc gggcggcgtc
    21961 catcggccgc aaaaccgggc cgcatcgagc ggtggggcgg cgtccaccgg tcgggcgatg
    22021 tgggccggtc gggcggggtg ggtcggcctg cgtcggttgg cccgcgtcgg tcggtcggag
    22081 ggcgtccgtc gggtcgcgtg cgtcggggcg ggccttcggg tcgcgtcgat tggtcggagt
    22141 gatcggcctg ggccatggcg cggggctggt cagggtgggt cagcaggggt gggggagccg
    22201 gcggtgaccg agcgcagttc ggtcatggtc gcgcgcatga cctcccgcag gtcggcgtcg
    22261 caggcggggt cgtcggccca gcgttcgaag gcgacgcgga agaccgccat gcccgcctcg
    22321 gcggccaggc tcgcggccgg ctcggggacg ccgcgctcgc gcaaggcgcc ggccagggcg
    22381 gccgacagcg acgccagctt gatcagctcg cgctcgcgca gctcggcgtg ggcgagcacg
    22441 acggcctgcc gccgccgggc ccgctcccgg cgctcctgca ggatgacccc agccacgtcc
    22501 agggcggccg cgatcgccgc catgggcgcg actggctcgg gcgcggcggc gaccgcctcc
    22561 gtcaggcgtt cgtggagcag cgtcgacccg ccgaacaaca cctcgcgctt gtcggcgaag
    22621 tggcggaaga acgtgcgctc ggtcagcccg gcccgccggg cgatctcggc aactgtcgtc
    22681 tgctcgtagc cgcgctcgcc gaacagctcc agcgccgcct cctccagccg gccgcgcgcg
    22741 ttcggctccc atcgccccat gcctcccgat catagtcgat gtcagtcgct gacatcagac
    22801 gcgctatgct gatgacagca actgacatca ccatcgtcgg aggtctctca tgcgtgtctt
    22861 cgtcaccggc gcgtccggct ggatcggatc cgccgtcgtc cccgagctca tcgcggcggg
    22921 gcaccaggtc accgggctcg cccggtccga ggccacggcg cgcg
//
