LOCUS       NZ_JAKRKC020000001     21137 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Actinomadura luzonensis strain ATCC 31491 Contig00003, whole genome
            shotgun sequence.
ACCESSION   NZ_JAKRKC020000001
VERSION     NZ_JAKRKC020000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura luzonensis
  ORGANISM  Actinomadura luzonensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 6358096)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Genome draft of Actinomadura sp. ATCC 31491
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6358096)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
REFERENCE   3  (bases 1 to 6358096)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. v1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 89.6x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022664455.2-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:46:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,232
            CDSs (total)                      :: 10,155
            Genes (coding)                    :: 10,004
            CDSs (with protein)               :: 10,004
            Genes (RNA)                       :: 77
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 36 of 151
            Pseudo Genes (incomplete)         :: 126 of 151
            Pseudo Genes (internal stop)      :: 3 of 151
            Pseudo Genes (multiple problems)  :: 14 of 151
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1732208
            Orig. end                         :: 1753345
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAKRKC020000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21137
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="7"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21137
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21137
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11137](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11137)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            65..718
                     /locus_tag="MF672_RS08215"
                     /old_locus_tag="MF672_008215"
     CDS             65..718
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889932.1"
                     /locus_tag="MF672_RS08215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008215"
                     /product="response regulator transcription factor"
                     /protein_id="WP_242375444.1"
                     /transl_table=11
                     /translation="MSVRVVVADDQDLVRAGLRLVIGTQDDLEVVGEARDGREAVELAR
                     RLRPDVALLDIAMPVMTGLTAAGRVLALPEPPRVILLTTYDTDEHLEGALAAGVSGFLL
                     KTSPPERLFAALRAAATGEALLDPAVTPRVIAGYAGRRAARPSLDGLTPRETDILRLVA
                     RGRTNAEIAAGLFITQATVGTHINRLLAKLSLRSRAQLVAHAYEAGLLRPGDDD"
     gene            complement(747..1439)
                     /locus_tag="MF672_RS08220"
                     /old_locus_tag="MF672_008220"
     CDS             complement(747..1439)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="MF672_RS08220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008220"
                     /product="ATP-binding protein"
                     /protein_id="WP_242375445.1"
                     /transl_table=11
                     /translation="MDQPFDRDSLYVLRATMEAHAVQAGLPEGRTSDLVLAVHELATNV
                     ILHGSGAGRVRMLAVDGLLRCEVIDSRATAATRETPPWPYEYGHGLWIVRSLGDLHSVT
                     RGPGGTVATIGFAVPEAGRPSFRLLQHERDGTVTLRLIGDLDQTTSGDLVAAVQALLKV
                     RAAGRLVLDLGGMTYWDSTGIAALLSVQERVSAVPGAALTLSGLSGDFRRRLDALSFQP
                     LSYDEPAG"
     misc_feature    1423..1438
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.03"
                     /tool="antismash"
     gene            complement(1507..2376)
                     /locus_tag="MF672_RS08225"
                     /old_locus_tag="MF672_008225"
     CDS             complement(1507..2376)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025774.5"
                     /locus_tag="MF672_RS08225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008225"
                     /product="MEDS domain-containing protein"
                     /protein_id="WP_242375446.1"
                     /transl_table=11
                     /translation="MTVSAETQITDLTINDHACLTYGESEELLDLTAAFVRDGLSAGQR
                     VVWLAEEPERRLGELRRRGVVAPAAAVTGRMMVLACQDSLLNGQAFAVGHAMAWLRDQM
                     EVTSQAGYPGLRVALDMSWALRPITGIEQLPAFEEEIASALGGVSTAVLCQYDRERFDP
                     VTLASVSGYHTRSVAAATYHHDPLLRICRQYAPSGIRLAGQLDRTAESALGLALAEAIR
                     FDGEVTVNMAELSFIDLYCARMIIDAARSLPPPRTAVLRCSPAVSARFRLLGATGVPGV
                     SLVTAHDG"
     misc_feature    complement(2002..2004)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2562..3761)
                     /locus_tag="MF672_RS08230"
                     /old_locus_tag="MF672_008230"
     CDS             complement(2562..3761)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543243.1"
                     /locus_tag="MF672_RS08230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008230"
                     /product="site-2 protease family protein"
                     /protein_id="WP_242375447.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 1.9e-08, bitscore:
                     32.4, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSSFRLGRLGGVEVGVNISVLVIVLILVAGLAFGQFPLAFPGRS
                     VVAYLLAGLASAVLFLASLLAHELAHALVAKRNGIEVPRITLWLLGGVAELRSEPRTPG
                     ADLRIAIVGPLTSLACGVVSGALALVTGGAPLVAGMFAYLAAVNVLLAVFNLIPAAPLD
                     GGRVLRAALWARWGDRVRAAVAAARAGRVFGYALIALGFLQVVTGLGFQGLWLVLIGLF
                     LVNAASAEEQQAQLGAALHGVRVGDVMSGEPVTAAPDETVAGLIDRLVMSRRLSTYPLV
                     DADGLFLGLVTLNRLREVPPEQRAATRLGDIACPPEAVPKAVPDEPLTGLLPRMSGCAD
                     GRAVVLGPSGRLLGLLTPSDISRAIQTAGLHGHDPYPHPRGADLTVPPQREQERRRSEV
                     "
     misc_feature    complement(3829..3842)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.87"
                     /tool="antismash"
     gene            3832..4929
                     /locus_tag="MF672_RS08235"
                     /old_locus_tag="MF672_008235"
     CDS             3832..4929
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (22-187). E-value: 7.5e-21.
                     Score: 66.8. Matches aSDomain:
                     nrpspksdomains_MF672_RS08235_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017615684.1"
                     /locus_tag="MF672_RS08235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008235"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_242375448.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-37, bitscore:
                     127.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRFRGPGAGYGVTLMKVKDKVVVITGASSGIGRATARAFAARG
                     AAVVLAARREEALAEARRECEAAGGRALAVPTDVTDPHAVQELARRAAERFGRIDVWVN
                     CAAVHLLGPFSDVPLADFRRVLDVNVMGYVHGARAALPYLREQGRGVLVNVSSVAGAVA
                     QPYAAAYCMSKAAVRSLSASIRQELRLEGLRGVRVCAVLPAAIDTPIFQHAANYTGRQV
                     RALPPVYRAERVARAIVDVVRWPRKEAVVGPMARNLISQSKLTPGLVERMMAVEVDRAH
                     LSRRRPAPASEGNLYRPEDGAGSVTGGWHGARRTMVRRALTAAAVAGTLAYARRARRAQ
                     RPLSPLNLLSRAGVPSGWCRPSGRA"
     aSDomain        3898..4392
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MF672_RS08235_PKS_KR.1"
                     /evalue="7.50E-21"
                     /label="MF672_RS08235_PKS_KR.1"
                     /locus_tag="MF672_RS08235"
                     /protein_end="187"
                     /protein_start="22"
                     /score="66.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGRATARAFAARGAAVVLAARREEALAEARRECEA
                     AGGRALAVPTDVTDPHAVQELARRAAERFGRIDVWVNCAAVHLLGPFSDVPLADFRRVL
                     DVNVMGYVHGARAALPYLREQGRGVLVNVSSVAGAVAQPYAAAYCMSKAAVRSLSASIR
                     QE"
     CDS_motif       3901..3993
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MF672_RS08235_0001"
                     /evalue="2.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="MF672_RS08235"
                     /protein_end="54"
                     /protein_start="23"
                     /score="20.3"
                     /tool="antismash"
                     /translation="VVITGASSGIGRATARAFAARGAAVVLAARR"
     gene            complement(4868..5386)
                     /locus_tag="MF672_RS08240"
                     /old_locus_tag="MF672_008240"
     CDS             complement(4868..5386)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017555981.1"
                     /locus_tag="MF672_RS08240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008240"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_242375449.1"
                     /transl_table=11
                     /translation="MAPTAAVIRPATPADLAAVTAINAHYVAETVITFEENPPSEADWQ
                     AKLADLTGRGLPFLVADLGGEVAGYAYAGPWRPKPAYRHTVEDTIYLAPAHVGRGLGDA
                     LLGELVRRSEAAGLRRMIAVIADAGDDRSVALHRRHGFTEVGRLTEVGFKLGRWVDTTL
                     MERPLATAG"
     gene            complement(5423..5857)
                     /locus_tag="MF672_RS08245"
                     /old_locus_tag="MF672_008245"
     CDS             complement(5423..5857)
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543245.1"
                     /locus_tag="MF672_RS08245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008245"
                     /product="protein-tyrosine phosphatase family protein"
                     /protein_id="WP_242375450.1"
                     /transl_table=11
                     /translation="MSALVGAIRLPDGLWVRGRGLRRPLPPGPVPDFGLYLGSARLRRR
                     HDAALTWPHEWVEWPDFLLPRDRDLAVRRIRELRERAAAGQAVEVACGGGVGRTGTVLA
                     CLAVSSGLDPAAAVAWTREHHHPRAIETPWQRRWIARFPL"
     gene            complement(5898..6470)
                     /locus_tag="MF672_RS08250"
                     /old_locus_tag="MF672_008250"
     CDS             complement(5898..6470)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543246.1"
                     /locus_tag="MF672_RS08250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008250"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_242375451.1"
                     /transl_table=11
                     /translation="MIIPIAGYPAGATVASDLVATSPTVRGAAGEGLPSPGALAEFLAG
                     HGLVLDAPPPDAAALREVHLLRRETRGVIETETEEQAVAGAMVLAGRAGRSPVLRRDDD
                     GAWQWRVPTAPGAPLAAELAAVIGIGLLGAVRALGHGRFRACAAPGCRGVFVDVSRAGR
                     RAYCTPDRCGNRVNVALHRARLRGAAR"
     misc_feature    6501..6514
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 12.43"
                     /tool="antismash"
     gene            6538..7122
                     /locus_tag="MF672_RS08255"
                     /old_locus_tag="MF672_008255"
     CDS             6538..7122
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891658.1"
                     /locus_tag="MF672_RS08255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008255"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_242375508.1"
                     /transl_table=11
                     /translation="MNLEALGRHIQELRHDRAMTLQQLARAADVSVSMLSAVERGHKAP
                     TIVVLARIAEGLGVPVAELVAAPDDQRVVVRRAAEQEHIDEPGGWRRTVLTPVVPGVNF
                     EWIRTTLPPGCDAGPFPAYAAGSHEYVAVESGTLRLTLGGRALDLDAGDSVYFAADVEH
                     SYANPGAAPCAYYVAAIVMRPRRAGRDRPAR"
     misc_feature    complement(7156..7172)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.03"
                     /tool="antismash"
     misc_feature    7198..7212
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.13"
                     /tool="antismash"
     gene            7243..7629
                     /locus_tag="MF672_RS08260"
                     /old_locus_tag="MF672_008260"
     CDS             7243..7629
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00377.1"
                     /locus_tag="MF672_RS08260"
                     /note="This anti-anti-sigma factor, or anti-sigma factor
                     antagonist, belongs to a family that includes characterized
                     members SpoIIAA, RsbV, RsfA, and RsfB; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="MF672_008260"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_242375452.1"
                     /transl_table=11
                     /translation="MLDLTFAVQNLPGVCVISVAGEIDSVTAREFDRYIQRNRRAPGEH
                     VVIDLSEVTFLASAGLRVLLNTHAFARQHGAVLHLAAPHPKIAGIMELTQANTVLHVHD
                     TVEQAVIAALQQAGAREKTLTQAT"
     misc_feature    7247..7261
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.49"
                     /tool="antismash"
     misc_feature    7854..7870
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.41"
                     /tool="antismash"
     gene            7869..9086
                     /locus_tag="MF672_RS08265"
                     /old_locus_tag="MF672_008265"
     CDS             7869..9086
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540093.1"
                     /locus_tag="MF672_RS08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008265"
                     /product="S1C family serine protease"
                     /protein_id="WP_242375453.1"
                     /transl_table=11
                     /translation="MDANEPREQAAGGWTQFGDTPPTAGGFPRREPAGPALPPPPPPRR
                     PGFLLTRKAIAGLAVAAAAALGVTALGGGAVGAYLAGADRPVAAASASAPSPVFRSVAD
                     QLTVAEVAAKVQPSVVMIQGRTAEGSGVVLSEDGLILTNNHVVSGQGDVLTVKFNDGRT
                     AKASVVGTDPATDLAVIRAEGVKGLAKATLGDSDQLKVGDDVLAVGSPLGLDGTVTAGI
                     VSALDRTVTAGDGGGGQQFPWGQQQQTETTTLGGMIQTDAAINPGNSGGALVNAAGELV
                     GINSAVSSEGVNLGFAIPVNTAKQVSQQLISKGKVSHAFLGVSVTDATGDVPGALIRQV
                     SAGSPADKAGLKQGDLITRIGDTKVDGGDTVVGQVRGFTVGQQVRITYLRDGKENTVTA
                     TMQQQK"
     gene            complement(9117..10004)
                     /locus_tag="MF672_RS08270"
                     /old_locus_tag="MF672_008270"
     CDS             complement(9117..10004)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (97-201). E-value: 3.5e-15. Score:
                     46.9. Matches aSDomain: nrpspksdomains_MF672_RS08270_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017584172.1"
                     /locus_tag="MF672_RS08270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008270"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_242375454.1"
                     /transl_table=11
                     /translation="MTVSRKDPARVTTTNAHNSVLGSQYQRSVADYWNAERNPVNLRLG
                     EVDGLYHHHYGIGHVDWSVLEGPEESREQRVVGELHRLETQQAETLVGHLGKLEPGDRV
                     MDAGSGRGGSSFLANLRHGCQVDGVSISESQVAFANEQARLRGVADQVRFHFRNMLDTR
                     FETGAFQAIWNNESTMYVELSLLFAEHSRLLRRGGRYVCITGCYNDAYGLPSRAISQIN
                     AHYICDIHSRSTYFRELVANRLVPCSVIDMTAATIPYWELRAKSHLATGIEEAFLEAYK
                     NGSFQYLLIAADRV"
     aSDomain        complement(9402..9713)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MF672_RS08270_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.50E-15"
                     /label="MF672_RS08270_oMT.1"
                     /locus_tag="MF672_RS08270"
                     /protein_end="201"
                     /protein_start="97"
                     /score="46.9"
                     /tool="antismash"
                     /translation="LEPGDRVMDAGSGRGGSSFLANLRHGCQVDGVSISESQVAFANEQ
                     ARLRGVADQVRFHFRNMLDTRFETGAFQAIWNNESTMYVELSLLFAEHSRLLRRGGRYV
                     "
     gene            complement(10001..11137)
                     /locus_tag="MF672_RS08275"
                     /old_locus_tag="MF672_008275"
     CDS             complement(10001..11137)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077431.1"
                     /locus_tag="MF672_RS08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008275"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_242375455.1"
                     /sec_met_domain="T1TS (E-value: 8.1e-55, bitscore: 185.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSPRVPVLPTGLGTSALSLCPPVPAPAGEEGDGHEPNLAAPPRH
                     LSLAPLPYVERPWGDGSYPPLLCPETVRVDDRLGAEVDRRLLAWAERLGLHEGRLEEFA
                     RTGFGRLIMLAHPDADDPDLLLIAAQLNTAWWAADDYYADETDLGATPTELPPRLALVM
                     SAMDPPPPAGDYTRELEEHIQADPVLVSLRSATAHLRRHATPAQVMRICGITFQMYVSW
                     CAYAAWRYLEAPPPVWRYLAARQHDSFYTSMTLIDIVGGYHLPADLFCDRRFHTALMQA
                     GTASVLVNDLHSVAKEAADELPDSNVILLIANEEGCSVEEATERAVHLHNDFVRGFEAS
                     RQALAAVPSPELKRFLRGAQAWMAGCLEWHGSSARYQS"
     gene            complement(11165..12559)
                     /locus_tag="MF672_RS08280"
                     /old_locus_tag="MF672_008280"
     CDS             complement(11165..12559)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017544766.1"
                     /locus_tag="MF672_RS08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008280"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_242375456.1"
                     /transl_table=11
                     /translation="MPTDPTEQRLSLDTRAARTLATTTKTRPQMQAITSRWLLRMLPWV
                     DVRGGTYRVNRRLTHRVGRGRVSVVQQGPDDVRVIPETLAELRALRGYDDLDVLSAIAA
                     TFTPRDVAPGEVIVEAGAPVTETYVVAHGRLEKQAAGRYGATEALGVITDGDQFGDEAL
                     GQDDPRWSCTVRAATAGTVLVSPWAAFQRILARAPGLQAHLDRYLADARRPVNKRGEAA
                     VEIAAGHVGEPTIGGTFVDYDLRPREYELSVSQTVLRVHTRVADLYNHPMSQLDEQLRL
                     TVHEIRERQEHELLNNREFGLLHNADYDQRLSTWSGPPTPDDLDDLISMRRKTRLLLAH
                     PRAIAAFFRECNKRGLVPGSAEVNGHEIPAWRGIPIFPCGKIPVSEQQTTSIIAMRVGE
                     DDQGVVGLHQTGLPEEREPGLSVRFMGINDQAVMSYLVTAYYSAAILVPDAIGILENAD
                     VAAPRS"
     gene            complement(12694..13005)
                     /locus_tag="MF672_RS08285"
                     /old_locus_tag="MF672_008285"
     CDS             complement(12694..13005)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543251.1"
                     /locus_tag="MF672_RS08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008285"
                     /product="EthD family reductase"
                     /protein_id="WP_242375457.1"
                     /transl_table=11
                     /translation="MAFQLIVLYNHPESTEAFDKHYDGTHAPLAARLPGLRSYTVTRPA
                     AGPAGRPPYYLVAVLTWDDEAAFGAAMAGEHGKATAADLANFAGAGVEMLVGPATAIV"
     gene            complement(13068..13337)
                     /locus_tag="MF672_RS08290"
                     /old_locus_tag="MF672_008290"
     CDS             complement(13068..13337)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543252.1"
                     /locus_tag="MF672_RS08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008290"
                     /product="hypothetical protein"
                     /protein_id="WP_242375458.1"
                     /transl_table=11
                     /translation="MTNEPIDTRLIDRECVRRLLESDRDDATLVFVRGECVVLPDAEVD
                     DAHRGLVVARRDEVLAQLPSQELTDQVLDDLAHRLDNVVRDLGA"
     gene            complement(13385..13753)
                     /locus_tag="MF672_RS08295"
                     /old_locus_tag="MF672_008295"
     CDS             complement(13385..13753)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_008295"
                     /product="hypothetical protein"
                     /protein_id="WP_242375459.1"
                     /transl_table=11
                     /translation="MTGRDENPDDEFFAPVLREPPPGGSGARQEPGPVSDTGVPGVHGA
                     GRGDWAKEPPPRNSLSYRLLAAGLVLLAGVVLAVWALLAGHPALAIGPAVVALAAAVYL
                     VAFGVRRARSDGGPPTFG"
     gene            complement(13740..14354)
                     /locus_tag="MF672_RS08300"
                     /old_locus_tag="MF672_008300"
     CDS             complement(13740..14354)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_008300"
                     /product="hypothetical protein"
                     /protein_id="WP_242375460.1"
                     /transl_table=11
                     /translation="MAGSQAFWIDAAREGAQARYGEQLRRWRHLFAAERETDAAVTLDP
                     LRFALGAWEVATRPITDVPYVRCHPRVLDATCHRPEETRGPLAVVELAVPPPVPLPAGW
                     RTWQRSPAGDDREVGDGRDAGAPGYAAPPYERPTALTTLELRAPLSPGRLPTPTHARAA
                     GLPNLDDAQASLEALVAELNEVVTPFLRALEEEEVNPHDRT"
     gene            complement(14373..14831)
                     /locus_tag="MF672_RS08305"
                     /old_locus_tag="MF672_008305"
     CDS             complement(14373..14831)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854508.1"
                     /locus_tag="MF672_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008305"
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="WP_242375461.1"
                     /transl_table=11
                     /translation="MALPTKRHRAPMQWGNTTLPSRSWDPFTEFQQLWDQMGRLFEQGE
                     ADAAVWRPVAETEEAAEAYLVRAELPGLRRDEVNVEIDGNELCISGEISEDDKGNRLKR
                     RTGKFAYRTILPADADTDRVGCELSDGVLTVRVPKTEQGRSRRISIRG"
     misc_feature    complement(14853..14867)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.96"
                     /tool="antismash"
     misc_feature    complement(15038..15051)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     gene            15074..16408
                     /locus_tag="MF672_RS08310"
                     /old_locus_tag="MF672_008310"
     CDS             15074..16408
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_008310"
                     /product="hypothetical protein"
                     /protein_id="WP_242375462.1"
                     /transl_table=11
                     /translation="MAQEPRIDVEINARTVESSLAPDQIERIASALGDPGVWFAAPPVR
                     EGEARRPDAVWELVADQPHRGHVATGRAHVHLAEGRTAPVRPLIFADGFNYGPSDLASM
                     WRHFDAPYEPGVPGLLDQVLAMGIDVVLLGFDQRQTYVQANAGVAITCLRRTLQERQGD
                     TPLVVGGVGTGGMITRYALARMESEGVDHQTDKYFSYDTPHLGAWIPLVLQQLAYLHET
                     IQPRLDGAGQAELIRSPAAQQLLWGWVPGTGYSGPVTSSSPLRKELLEDLRRVGRFPMR
                     PYKLGLANGGGDGRGPDLPPGTPVLDLGEGPLRLAARIQPDGGELRNVGAIGFGEPVWT
                     SATSHVAAFDGAPGGTLDAFGRVADAMGLPIQDRFRGTCFVPSVSAIALAREPLAWQSE
                     LYADLRELPKDETFLDAFCCDTGNGPHGAVSATLAEWFVGQLAGW"
     gene            complement(16467..17867)
                     /locus_tag="MF672_RS08315"
                     /old_locus_tag="MF672_008315"
     CDS             complement(16467..17867)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_008315"
                     /product="hypothetical protein"
                     /protein_id="WP_242375463.1"
                     /transl_table=11
                     /translation="MDENRTDISELGIDAEAPLLQAQDDPIAAAAVDIAVETELLEDDD
                     LANRAAAEAEWLAARRDSERRIRELDARDQDRVRRLQSELRAVGAEVWPVARWWGFEVN
                     LNEQAAVRAAELAALIGETAGAVLGGWLAPVVEWSARNKARWIASVARPYGARLVSPWT
                     APASLVPIRVAGVPTGDARLWWAVHEPGEGWSEDQRFVDHFTASGAALAEYRDRLYVAH
                     RGSDGDSALWWAVYDAEQGWSEDQRFPRHFSASAPALAVYDDQLYCVHRGADQDSALWW
                     ARWDGSQWSQDARLPRHFSAGSPALAGYDGKLWCVHRGAHDDSLWWTTWDGGQWSEDQR
                     FPRHASRSNPALAVFRGHLYCVHRGAGDDTALWWTRWDGSSWSPDERLPGHFSAEGPAL
                     TVYKDRLYVVHRGAADQSLWWAVFDGANWSADERLPGHYSAEAPAAIAYRDRNATRDQL
                     LVLHRGSR"
     gene            complement(18124..19566)
                     /locus_tag="MF672_RS08320"
                     /old_locus_tag="MF672_008320"
     CDS             complement(18124..19566)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009084602.1"
                     /locus_tag="MF672_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008320"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_242375464.1"
                     /transl_table=11
                     /translation="MSRRISMSLETKLVVSSIALLAVVSAVIATATTLLFEDFLTDRLD
                     IQVSSAARRSAGASAEPPAGLAPEAAREVWFLLSPGQAEGTFGARVRLGRVHRAAVLSG
                     GTVRDVPAPPKVAAVTGRPVTVDLGRLGAYRMASRPAPDGDVLVTGLPLNGVESTLTRL
                     VMVEAAVTLAGVALTAAAGTLLVRHAVRPLGRLAATAARVSELPLATGDAVRLARVPEP
                     DTDPRTEIGQVGGALNRMLGHVETAFAVRHESETRLRRFIADASHELRTPLASIVGYAE
                     LTRRSGEPHGPQTTHALGRISSEAGRMTTLVEDLLLLARLDAGRPLERVELDLSPLVVT
                     AVGDAYAAAPRHRWLVSLPDQPALVVGDADRLHQVLTNLLANARTHTPPGTTVTTTVLA
                     DGGEVRVRVADDGPGIAPHVLPHVFGRFARGDGSRSRRAGGSGLGLAIVSAVAAAHEGR
                     VEVASVPGSTVFTLTLPAAAPA"
     gene            complement(19563..20303)
                     /locus_tag="MF672_RS08325"
                     /old_locus_tag="MF672_008325"
     CDS             complement(19563..20303)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017888661.1"
                     /locus_tag="MF672_RS08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_008325"
                     /product="response regulator transcription factor"
                     /protein_id="WP_302893179.1"
                     /transl_table=11
                     /translation="MHTTSPNLQSEPVRRPDGSPINILVVDDEPALTELLSMVMRQESW
                     DVRSAHNGGEAIRAARGFRPDAIVLDVMLPDMDGVELLPRLRAVLPGVPVLFLTAKDSV
                     QDRLAGLRAGADDYVTKPFSLEEVVIRLRGLLRRSGAVRVRPDAVLVVGDLTLDQETRE
                     VRRGGTEVKLTPTEFELLRFLMHNPGRVLSKAQILDRVWAYDFGGQSNVVELYISYLRR
                     KIDARRAPMIHTVRGVGYTLRPAG"
     misc_feature    20481..20494
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    21050..21063
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.1"
                     /tool="antismash"
ORIGIN
        1 gggcgggggc tggggccggg gcggcggcga caggtccggc ggtgggcccg gcggtgcgcg
       61 ggcgatgagc gtgcgcgtcg tggtggccga cgaccaggac ctggtcaggg ccgggttgcg
      121 gctggtcatc ggcacccagg acgacctgga ggtcgtgggc gaggcgcgcg acggccgcga
      181 ggcggtggag ctggcccggc ggctccgccc ggacgtggcg ctgctggaca tcgcgatgcc
      241 ggtgatgacc gggctcaccg cggccgggcg cgtcctcgcc ctgccggagc cgccgcgggt
      301 gatcctgctg accacgtacg acacggacga gcacctggag ggggcgctcg ccgccggggt
      361 gagcgggttc ctgctcaaga cctcgccgcc ggagcggctc ttcgcggccc tgcgggcggc
      421 ggccacgggc gaggcgctgc tcgacccggc cgtgacgccg cgagtgatcg ccgggtacgc
      481 cggccgccgg gccgcgcggc cgtccctgga cgggctgacc ccgcgcgaga ccgacatcct
      541 gcgcctggtg gcgcgcggca ggacgaacgc cgagatcgcc gccggcctgt tcatcacgca
      601 ggccacggtc ggcacgcaca tcaaccggct gctggccaag ctgtcgctgc gcagccgcgc
      661 gcagctcgtc gcgcacgcct acgaggccgg gctgctgcgg ccgggcgacg acgactgagg
      721 aggaggagga ggaggtaggg gcggcgtcag ccggcgggct cgtcgtagct gagcggctgg
      781 aaggagaggg cgtcgaggcg gcggcggaag tcgcccgaca ggccgctgag cgtgagcgcg
      841 gccccgggga cggcgctgac ccgctcctgc accgacagga gggcggcgat gccggtggag
      901 tcccagtacg tcatgccgcc gaggtccagc acgagccggc ccgccgcgcg gaccttcagc
      961 agcgcctgga cggcggcgac gaggtcgccg gaggtggtct ggtcgaggtc gccgatcagg
     1021 cgcagggtga cggtgccgtc gcgttcgtgc tggagcagcc ggaaggaggg gcggccggcc
     1081 tcggggacgg cgaagccgat ggtggccacg gtgccgccgg ggccgcgcgt cacgctgtgc
     1141 aggtcgccga gggagcggac gatccacagg ccgtggccgt actcgtaggg ccacggcggg
     1201 gtctcccgcg tcgcggcggt ggcgcgggag tcgatcacct cgcaccggag caggccgtcc
     1261 acggccagca tgcggacccg gccggcgccc gagccgtgca ggatgacgtt ggtggccagc
     1321 tcgtggacgg cgagcacgag gtcggacgtg cggccctccg gcagcccggc ctggacggcg
     1381 tgcgcctcca tcgtcgctct gagcacgtac agggaatcgc ggtcgaaggg ctgatccaca
     1441 acgctctcca ggccgcctgg acctgctgcg ccgccggagg ccgggaggcg gctgtgcggg
     1501 ggccggtcat ccgtcatggg cggtcaccag gctcactccg gggacgccgg tcgcgccgag
     1561 caggcggaac cgggcgctga ccgccgggct gcagcgcagc acggccgtgc ggggcggggg
     1621 caggctacgg gcggcgtcaa tgatcatgcg tgcgcagtac aggtcgatga acgacagctc
     1681 cgccatgttg accgtcacct cgccgtcgaa ccggatggcc tcggcgagcg ccagcccgag
     1741 cgcgctctcg gcggtgcggt cgagctgccc ggccagccgg atgccggagg gcgcgtactg
     1801 gcggcagatg cgcagcagcg gatcatggtg gtaggtggcc gcggcgaccg aacgggtgtg
     1861 gtagccggag acggaggcga gcgtgaccgg gtcgaagcgc tcgcggtcgt actggcacag
     1921 caccgccgtg ctgaccccgc ccagcgcgga ggcgatctcc tcctcgaacg ccgggagctg
     1981 ctcgatgccg gtgatcgggc gtaatgccca gctcatgtcg agcgccaccc gcaaccccgg
     2041 atagcccgcc tggctggtga cctccatctg gtcgcggagc caggccatcg cgtggcccac
     2101 cgcgaacgcc tgcccgttca gcaggctgtc ctggcaggcc agcaccatca tgcggccggt
     2161 gaccgcggcc gccggcgcga ccacgccccg ccgccgcagc tcgcccagcc gccgctcggg
     2221 ctcctcggcc agccacacga cccgctgccc ggcggacagc ccgtcgcgga cgaacgcggc
     2281 ggtgaggtcg agcagctcct cgctctcgcc gtaggtgagg caggcgtgat cgttgatcgt
     2341 cagatccgtg atctgcgttt cagcgctgac ggtcacccac gccacccttc gtcccggccc
     2401 cctacagtag tgatcaagag gcgggtccgg cagccgcggg gaccgctctt gcgcgacctc
     2461 ccccgctacc cccgcagcgg cggacgacac ctgctcactc ctggccatga ttatggacag
     2521 gtcagggccg tcgcgggcgc ggttcgcggc aggaggggcg gtcacacctc gctacggcgc
     2581 cgctcctgct cgcgctgcgg cggcaccgtg aggtcggcgc cgcgcgggtg cgggtagggg
     2641 tcgtggccgt gcaggccggc ggtctggatc gcgcggctga tgtcgctcgg ggtgagcagc
     2701 ccgaggagcc ggccggacgg gccgagcacc acggcccggc cgtcggcgca gccgctcatc
     2761 cgcggcagca ggccggtcag cggctcgtcg ggcacggcct tcggcacggc ttccggcggg
     2821 caggcgatgt cgccgagccg ggtggccgcc cgctgctcgg gcggcacctc gcgcagccgg
     2881 ttgagcgtca ccaggccgag gaagaggccg tcggcgtcca ccagcgggta cgtcgacagc
     2941 cgccggctca tcaccagccg gtcgatgagc ccggcgacgg tctcgtccgg cgcggcggtg
     3001 acgggctcgc ccgacatgac gtcgccgacc cgcaccccgt gcagcgcggc gccgagctgg
     3061 gcctgctgct cctcggcgct ggcggcgttc accaggaaca ggccgatcag gaccagccac
     3121 agcccctgaa agcccagccc ggtgacgacc tggaggaaac cgagggcgat gagcgcgtag
     3181 ccgaagacgc gcccggcgcg ggcggcggcg acggcggcgc gcacccggtc gccccagcgg
     3241 gcccagagcg cggcgcgcag cacccggccg ccgtccagcg gcgcggccgg gatcaggttg
     3301 aacacggcga gcagcacgtt gaccgccgca agataggcga acatgccggc caccagcggc
     3361 gcgccccccg tgaccagcgc cagcgcgccg gacaccaccc cgcaggccag gctggtcagc
     3421 ggcccgacga tcgcgatccg caggtccgcg cccggcgtgc ggggctcgct ccgcagctcc
     3481 gccaccccgc cgagcagcca cagcgtgatg cgcggcacct cgatgccgtt gcgcttggcc
     3541 accagggcgt gcgccagctc gtgcgcgagc agcgaggcca ggaacagcac cgcggaggcc
     3601 agcccggcca gcaggtacgc cacgacggag cgaccgggga aggcgagcgg gaactgcccg
     3661 aaggccagcc cggccaccag gatcagcacg atgaccagca cgctgatgtt gacgccgacc
     3721 tcgaccccgc cgagacggcc caaccggaac gacgaacgca tggtgcctgc tcctccgctc
     3781 ggatgcggtc cggctacccg cctgtggccg gagaaacctc ccccgacctg catgatcgtc
     3841 cggtttcgcg gccccggtgc cgggtacggc gtgacgctca tgaaggtcaa ggacaaggtc
     3901 gtcgtgatca ccggcgcgtc cagcgggatc ggccgggcga ccgcccgcgc cttcgccgcc
     3961 cggggcgccg ccgtggtgct ggccgcccgg cgcgaggagg cgctggccga ggcgcggcgc
     4021 gagtgcgagg cggccggcgg ccgggcgctc gcggtgccca ccgacgtgac cgacccgcac
     4081 gcggtgcagg agctggcccg gcgggcggcc gagcggttcg ggcgcatcga cgtgtgggtg
     4141 aactgcgcgg ccgtgcacct gctcggcccg ttctccgacg tgccgctggc ggacttccgg
     4201 cgggtgctgg acgtcaacgt catggggtac gtgcacgggg ccagggcggc gctgccgtac
     4261 ctgcgggagc aggggcgggg cgtgctggtg aacgtctcgt ccgtggcggg ggcggtggcg
     4321 cagccgtacg cggcggcgta ctgcatgtcg aaggcggccg tccggtcgct gagcgcgagc
     4381 atcaggcagg agctgcggct ggaggggctg cgcggggtgc gggtgtgcgc ggtgctgccc
     4441 gccgccatcg acacgccgat cttccagcac gccgcgaact acacgggccg ccaggtgcgg
     4501 gcgctgccgc cggtgtaccg ggccgagcgg gtggcgcggg cgatcgtgga cgtggtgcgg
     4561 tggccgcgca aggaggccgt ggtcgggccg atggcacgca acctcataag ccagtcgaag
     4621 ctgacgccgg ggctggtcga gcggatgatg gcggtggagg tggaccgggc gcacctgtcg
     4681 cggaggcggc cggcgccggc ctcggagggc aacctgtacc ggccggagga cggggcgggc
     4741 tcggtgacgg gcggctggca cggcgcgcgc aggaccatgg tgcgccgggc cctgacggcg
     4801 gcggcggtgg ccggcaccct cgcctacgcc cgccgcgccc gtcgcgccca gcggcccctg
     4861 agcccgctca acctgctgtc gcgagcgggc gttccatcag ggtggtgtcg acccagcggc
     4921 cgagcttgaa gcccacctcg gtcagccggc ctacctcggt gaagccgtgg cggcggtgca
     4981 gcgccaccga gcggtcgtcg cccgcgtcgg cgatgacggc gatcatgcgg cgcaggccgg
     5041 ccgcctcgga ccgccgtacc agctcgccga gcagcgcgtc gccgaggccg cggccgacgt
     5101 gggccggggc caggtagatc gtgtcctcca ccgtgtgccg gtaggcgggc ttgggccgcc
     5161 agggaccggc gtaggcgtag ccggcgacct cgccgccgag gtcggcgacg aggaagggca
     5221 ggccgcggcc ggtgaggtcg gccagcttgg cctgccagtc ggcctccgac ggcgggttct
     5281 cctcgaaggt gatcacggtt tcggcgacgt agtgggcgtt gatcgcggtc acggccgcca
     5341 ggtcggcggg ggtggccggg cggatgacgg ctgcggtggg cgccacggcg atcgcctttc
     5401 tctatagcga aatccgctcg cattatagag gaaagcgcgc gatccagcgg cgttgccagg
     5461 gcgtctcgat cgcgcgggga tggtggtgct cgcgcgtcca cgccacggcg gcggccgggt
     5521 ccagcccgga cgacaccgcc aggcaggcga gcaccgtccc ggtgcggccg acgccgccgc
     5581 cgcaggccac ctccaccgcc tggccggccg ccgctcgctc gcgcagctcc ctgatgcggc
     5641 gcacggcgag gtcgcggtcg cggggcagca ggaagtcggg ccactcgacc cactcgtgcg
     5701 gccaggtcag cgccgcgtcg tggcggcggc ggagccgggc ggagccgagg tagagcccga
     5761 agtcggggac cgggcccggc gggaggggcc gccgcagccc gcgcccccgc acccacaacc
     5821 cgtccggcag ccggatcgcg ccgacgaggg cgctcaccgg accacgcccc gcagccggat
     5881 cgcgccgacg agggcgctca tcgggccgcg cctcggaggc gggcgcggtg cagcgcgacg
     5941 ttgacccggt tgccgcaccg gtccggcgtg cagtacgcgc gccgccccgc ccggctgacg
     6001 tccacgaaca cgccccggca gccgggggcg gcgcaggcgc ggaagcggcc gtggccgagc
     6061 gcgcgcaccg cgcccagcag gccgatgccg atgaccgcgg ccagctcggc ggccagcggc
     6121 gcgccgggcg cggtgggcac gcgccactgc caggccccgt cgtcgtcgcg ccgcagcacc
     6181 ggggagcggc cggcgcgccc ggccagcacc atggccccgg ccacggcctg ctcctccgtc
     6241 tcggtctcga tgacgccgcg ggtctcgcgg cgcagcaggt gaacctcgcg cagggcggcc
     6301 gcgtcgggcg gcggggcgtc gaggacgagg ccgtgcccgg ccaggaactc cgccagcgcc
     6361 ccgggggacg gcagcccctc ccccgccgcg ccccgcaccg tcggcgaggt ggcgaccagg
     6421 tcgctcgcca ctgtggcgcc cgccgggtaa ccggcgatcg ggatgatcac tcgcacctcc
     6481 tgtaaccgtt gcaggacgac tataagcctt acaccccttc ggtacgatgt gctcttggtg
     6541 aacctcgaag ccctgggccg gcacattcag gagctccgcc acgaccgggc catgacgttg
     6601 cagcagctcg cccgcgcggc cgacgtgagc gtcagcatgc tgtccgcggt cgagcgcggc
     6661 cacaaggcgc ccacgatcgt cgtgctggcc cgcatcgccg agggcctcgg cgtgccggtg
     6721 gccgagctgg tcgccgcgcc cgacgaccag cgcgtcgtgg tgcggagggc cgccgagcag
     6781 gagcacatcg acgagccggg cggctggcgc aggacggtcc tgacgccggt ggtgccgggg
     6841 gtcaacttcg agtggatccg caccacgctg ccgccgggct gcgacgccgg ccccttcccc
     6901 gcctacgcgg cgggctccca cgagtacgtc gccgtcgagt ccggcacgct ccggctcacg
     6961 ctgggcgggc gcgcgctcga cctcgacgcg ggcgactcgg tctacttcgc cgccgacgtc
     7021 gagcactcct acgccaaccc gggggccgcc ccgtgcgcct actacgtggc cgcgatcgtc
     7081 atgcgcccca ggagagccgg ccgcgaccgt ccggcgaggt aagaattagc ccgccgcatc
     7141 ttctacaccg ggcggcgccc ggatatggtg cggtaaaggc aagccacgcc ttgtccatgt
     7201 tccctgagaa ttcgttctcg aattccgatc ggtgggcatc gcatgctgga tctcacgttc
     7261 gccgtgcaga atctgccggg cgtgtgcgtg atctccgtgg cgggcgagat agattcggtc
     7321 accgcccgcg agttcgaccg ttacatccag cgcaaccggc gggcgccggg cgagcacgtg
     7381 gtcatcgacc tgagcgaggt caccttcctc gccagcgccg ggctgcgggt gctgctcaac
     7441 acccacgctt tcgcccgtca gcacggcgcc gtgctgcatc tggccgcgcc gcatcccaag
     7501 atcgccggaa tcatggagct gactcaggcg aataccgttc tgcacgtgca cgacacggtg
     7561 gaacaggccg ttatcgccgc cctgcagcag gccggcgcgc gggagaaaac cctcactcag
     7621 gccacataag gaatcgcacg aaattcaccg gctgggctca cgggtcagca gcaggtcgag
     7681 ttcggcgtgc acggcggccg gcagcgcgcg cccgcagcga gttcggggga atttccggcc
     7741 gtgcccggcg tccccggcca gcggcgataa ggccggtgtc agagccggac gagccacccg
     7801 atctttccct taagcaggtc ttaccgggca ttgatcaccc tggtgtcatc gggacgctag
     7861 gagatgacat ggacgcgaac gaacctcgcg agcaggcagc cggtggctgg acccagttcg
     7921 gcgacacgcc gcccaccgcg ggcgggttcc cgcgcaggga accggccggc ccggcgctgc
     7981 cgccgcctcc gccgccgcgg cggccggggt tcctgctgac ccgcaaggcg atcgccgggc
     8041 tcgcggtggc cgccgcggcc gcgctcgggg tgacggcgct cggcggcggg gccgtcgggg
     8101 cgtacctggc cggggccgac cggccggtgg cggcggcgag cgcgagcgcg ccgagcccgg
     8161 tcttccgcag cgtggccgac cagctcacgg tggctgaggt ggcggcgaag gtgcagccgt
     8221 cggtggtgat gatccagggg cggacggccg agggctccgg cgtggtgctg tcggaggacg
     8281 gcctcatcct caccaacaac cacgtcgtca gcgggcaggg cgacgtgctg acggtcaagt
     8341 tcaacgacgg caggaccgcc aaggcgagcg tggtgggcac cgacccggcg accgacctcg
     8401 ccgtcatccg cgccgaaggc gtcaagggcc tggccaaggc cacgctcggc gacagcgacc
     8461 agctcaaggt cggcgacgac gtgctcgccg tcggcagccc gctcggcctg gacggcaccg
     8521 tgacggcggg catcgtcagc gccctcgacc gcacggtcac cgccggcgac ggcggcggcg
     8581 gccagcagtt cccctggggt cagcagcagc agaccgagac caccacgctc ggcggcatga
     8641 tccagaccga cgccgcgatc aacccgggca actccggcgg cgcgctggtc aacgcggccg
     8701 gcgagctggt cggcatcaac agcgcggtct cctccgaggg cgtcaacctc ggcttcgcga
     8761 tcccggtgaa caccgccaag caggtgtcgc agcagctcat cagcaagggc aaggtgagcc
     8821 acgccttcct cggcgtgagc gtcaccgacg ccaccggcga cgtgcccggc gcgctgatcc
     8881 gccaggtgag cgcgggcagc ccggcggaca aggccggcct caagcagggc gacctcatca
     8941 ccaggatcgg cgacaccaag gtcgacggcg gcgacacggt cgtcgggcag gtccgcgggt
     9001 tcaccgtggg gcagcaggtg cgcatcacgt acctgcggga cggcaaggag aacaccgtca
     9061 ccgccaccat gcagcagcag aagtagccgg gccgcccggc gggcggcccg gccggctcac
     9121 acccggtcgg cggcgatgag caggtactgg aagctgccgt tcttgtacgc ctccaggaac
     9181 gcctcctcga tgccggtcgc caggtggctc ttggcccgca gctcccagta ggggatggtg
     9241 gccgccgtca tgtcgatgac gctgcacggc accagccggt tggccaccag ctccctgaag
     9301 taggtgctgc gggagtggat gtcgcagatg tagtgggcgt tgatctggct gatggcccgg
     9361 gagggcaggc cgtaggcgtc gttgtagcag ccggtgatgc agacgtagcg cccgccgcgc
     9421 ctgagcaggc gggagtgctc ggcgaacagc agcgagagct cgacgtacat ggtgctctcg
     9481 ttgttccaga tcgcctggaa cgcgccggtc tcgaagcggg tgtcgagcat gttgcggaag
     9541 tggaagcgca cctggtcggc cacgccgcgc agcctcgcct gctcgttggc gaaggcgacc
     9601 tgcgactcgg agatcgacac cccgtccacc tggcagccgt gccgcaggtt ggccaggaag
     9661 ctggagccgc cccggccgga gccggcgtcc atgacgcggt cgccgggctc cagcttgccg
     9721 aggtggccga ccagcgtctc ggcctgctgg gtctccagcc ggtgcagctc gccgacgacg
     9781 cgctgctcgc ggctctcctc cggcccctcc agcaccgacc agtcgacgtg gccgatgccg
     9841 tagtggtggt ggtagaggcc gtccacctcg cccagcctga ggttgacggg attgcgctcg
     9901 gcgttccagt agtcggcgac ggagcgctgg tactggctgc cgagcacgga gttgtgggcg
     9961 ttcgtggtgg tcacgcgggc ggggtccttt ctgctgacgg tcatgactgg tagcgggcgc
    10021 tgctgccgtg ccattcgagg cagccggcca tccacgcctg cgcgccgcgc aggaagcgct
    10081 tcagctccgg cgacggcacg gcggccagcg cctgccggct cgcctcgaaa cctcggacga
    10141 agtcgttgtg caggtggacg gcgcgctcgg tcgcctcctc gaccgagcag ccctcctcgt
    10201 tggcgatgag caggatcacg ttgctgtcgg gcagctcgtc ggccgcctcc ttggccaccg
    10261 agtgcaggtc gttgaccagg acgctggcgg tgccggcctg catcagcgcg gtgtggaagc
    10321 ggcggtcgca gaacaggtcg gcgggcaggt ggtagccgcc gacgatgtcg atgagggtca
    10381 tcgaggtgta gaagctgtcg tgctggcggg ccgcgaggta gcgccacacc ggcggcgggg
    10441 cctccaggta gcgccaggcg gcgtaggcgc accagctcac gtacatctgg aacgtgatgc
    10501 cgcagatgcg catgacctgg gccggggtgg cgtgcctgcg caggtgggcg gtggccgagc
    10561 ggagcgagac cagcacgggg tcggcctgga tgtgctcctc cagctcgcgg gtgtagtcgc
    10621 cggcgggcgg cggcgggtcc atggcggaca tcaccagcgc caggcggggc ggcagctcgg
    10681 tcggggtggc gccgaggtcg gtctcgtcgg cgtagtagtc gtcggcggcc caccaggcgg
    10741 tgttgagctg ggcggcgatc agcagcaggt cggggtcgtc ggcgtcgggg tgggccagca
    10801 tgatcagccg gccgaacccg gtgcgggcga actcctccag ccgcccctcg tgcaggccca
    10861 gccgctcggc ccaggccagc agccgccggt cgacctccgc gccgagccgg tcgtcgacgc
    10921 ggacggtctc ggggcacagc agcggcgggt aggagccgtc gccccacggc cgctcgacgt
    10981 agggcagcgg ggccaggctg aggtgccggg gcggcgccgc gaggttgggc tcgtggccgt
    11041 cgccctcctc cccggcgggt gcggggacgg gcgggcagag gctgagcgcg gacgtgccga
    11101 ggccggtggg cagcaccggg acgcgggggg aaggcatgac gctcctcgtg ggaagggggc
    11161 cggatcagga gcgcggggcc gcgacgtcgg cgttctccag gatgccgatc gcgtcgggca
    11221 ccaggatcgc cgccgagtag taggcggtga ccaggtagga catcacggcc tggtcgttga
    11281 tgcccatgaa gcgcacgctg agccccggct cgcgctcctc cggcagcccg gtctgatgga
    11341 ggccgaccac gccctggtcg tcctcgccca cgcgcatcgc gatgatcgag gtggtctgct
    11401 gctcgctgac cgggatcttg ccgcagggga agatcgggat gccgcgccag gccgggatct
    11461 cgtggccgtt cacctcggcg ctgcccggca ccagcccgcg cttgttgcac tcgcggaaga
    11521 acgcggcgat cgccctcggg tgggccagca gcaggcgggt cttgcggcgc atgctgatga
    11581 ggtcgtcgag gtcgtcgggg gtgggcgggc ccgaccaggt ggacaggcgc tggtcgtagt
    11641 cggcgttgtg gagcagcccg aactcgcggt tgttgagcag ctcgtgctcc tggcgctcgc
    11701 ggatctcgtg cacggtgagg cggagctgct cgtcgagctg gctcatcggg tggttgtaga
    11761 ggtcggccac ccgggtgtgc acgcggagga cggtctggga gacgctcagc tcgtactcgc
    11821 ggggccgcag gtcgtagtcg acgaacgtgc cgccgatggt gggctcgccc acgtggccgg
    11881 cggcgatctc gaccgcggcc tcgccgcgct tgttgacggg cctgcgggcg tcggcgaggt
    11941 agcggtcgag gtgggcctgg agaccggggg cgcgggcgag gatgcgctgg aaggcggccc
    12001 acggcgagac gaggacggtg ccggcggtgg ccgcccgcac cgtgcacgac cagcgggggt
    12061 cgtcctggcc gagcgcctcg tcgccgaact ggtcgccgtc ggtgatgacg ccgagggcct
    12121 cggtggcgcc gtaccggccg gcggcctgct tctccaggcg gccgtgggcg acgacgtacg
    12181 tctcggtgac cggcgcgccg gcctccacga tcacctcgcc gggggcgacg tcgcggggcg
    12241 tgaacgtcgc ggcgatggcg gagagcacgt cgaggtcgtc gtagccgcgc agcgcccgca
    12301 gctcggccag cgtctccggg atgacgcgga cgtcgtcggg cccctgctgc accacgctca
    12361 cccggccgcg cccgacccgg tgcgtcaggc gccggttgac ccggtaggtg ccgccgcgca
    12421 cgtccaccca gggcagcatg cgcagcagcc accgggaggt gatggcctgc atctgggggc
    12481 gggtcttggt ggtggtggcc agggtgcggg cggccctggt gtccaggctc agccgctgtt
    12541 cggtggggtc cgtgggcatc ttccctcgca atcgccggct cctcgtcacc gaacgtattc
    12601 atatgaacac aatcggtaga gtctccagag ggatagggga tgcttacccc cggcccgggg
    12661 gcggcgatgc ccgtcccgcc gccccttcgc ccgctagacg atcgccgtgg cggggcccac
    12721 gagcatctcg acgcccgccc cggcgaagtt cgccaggtcg gcggccgtcg ccttgccgtg
    12781 ctcgccggcc atcgccgcgc cgaacgcggc ctcgtcgtcc caggtcagca cggcgaccag
    12841 atagtacggc ggccgccccg ccggccccgc cgcgggccgc gtcaccgtgt aggagcgcag
    12901 ccccggcagc cgcgcggcca gcggggcgtg cgtgccgtcg tagtgcttgt cgaacgcctc
    12961 ggtgctctcg gggtggttgt agagcacgat gagctggaat gccactgtct gcctcccgga
    13021 tcgtgggtgc ttcgatcaaa ccccggtccg ggccccggca ccagtgctca ggcgcccagg
    13081 tcgcggacga cgttgtccag ccggtgcgcc aggtcgtcga ggacctggtc ggtcagctcc
    13141 tggctcggga gctgggccag cacctcgtcg cggcgggcga cgaccagccc gcggtgcgcg
    13201 tcgtccacct ccgcgtcggg cagcaccacg cactcgccgc ggacgaagac cagcgtcgca
    13261 tcgtcgcggt cggactccag cagcctccgc acgcactcgc ggtcgatgag ccgggtgtcg
    13321 atgggctcgt tcgtcatgtc gtgcctcctc ctcgtcgagg cagggcgctc cgccccgccg
    13381 cgggtcaccc gaaggtgggc ggcccgccgt ccgatcgcgc ccggcgcacg ccgaacgcca
    13441 ccaggtacac cgccgccgcc agcgccacca cggccggccc gatcgccagc gccgggtggc
    13501 cggccagcag cgcccacacg gccaggacca ccccggccag caggaccagg cccgcggcga
    13561 gcaggcggta gctcagggag ttcctgggcg gcggctcctt cgcccagtcg ccccgccccg
    13621 cgccgtggac gccgggcacg ccggtgtcgc tcaccggccc gggctcctgc cgcgcgcccg
    13681 atccgccggg cgggggctca cgcagcacgg gggcgaagaa ctcgtcgtcc gggttctcgt
    13741 cacgtccggt catgggggtt cacctcttct tcctccaggg cgcgcaggaa gggtgtgacg
    13801 acctcgttca gctccgccac cagcgcctcc agcgacgcct gggcgtcgtc caggttcggc
    13861 aggcccgcgg cgcgggcgtg cgtgggggtg ggcagccggc ccggcgacag cggggcccgc
    13921 agctccagcg tggtcagggc ggtgggccgc tcgtacgggg gcgcggcgta cccgggcgcg
    13981 ccggcgtccc ggccgtcgcc gacttcccgg tcgtcgccgg cggggctgcg ctgccaggtg
    14041 cgccagccgg cggggagcgg caccggcggg gggacggcca gctcgaccac ggccagcggg
    14101 ccgcgcgtct cctccggccg gtggcaggtc gcgtcgagca cgcgcgggtg gcagcgcacg
    14161 tagggcacgt cggtgatcgg gcgcgtggcg acctcccacg cgcccagcgc gaaccgcagc
    14221 gggtcgagcg tgacggcggc gtccgtctcc cgttccgccg cgaacaggtg ccgccacctg
    14281 cgcaactgct ctccgtagcg ggcctgcgcg ccctcgcggg ccgcgtcgat ccagaacgcc
    14341 tggctcccgg ccatggcccc gcccccgccc ggtcagcccc gtatcgagat gcggcgcgag
    14401 cggccctgct cggtcttggg gacgcgcacg gtcagcacgc cgtcgctgag ctcgcagccg
    14461 acccggtccg tgtcggcgtc cgcgggcagg atggtgcggt aggcgaactt gccggtgcgc
    14521 cgcttgagcc ggttgccctt gtcgtcctcg ctgatctcgc ccgagatgca cagctcgttg
    14581 ccgtcgatct cgacgttgac ctcgtccctg cggaggcccg gcagctccgc gcgcaccagg
    14641 tacgcctccg ccgcctcctc ggtctcggcg accggacgcc agacggcggc gtcggcctcg
    14701 ccctgctcga acagccggcc catctggtcc cagagctgct ggaactcggt gaaggggtcc
    14761 cacgagcggg acgggagcgt cgtgttgccc cattgcatgg gcgctctgtg gcgcttggtg
    14821 gggagtgcca tcgctttcac ctccgtaacg acaggaacag atcgtccctg ctcatgtggc
    14881 tcatcgcgtc cctacccccg cgttaaccag caaactcggc gaagcgccgt ttcctgacac
    14941 tccggtgaac tgcgcttcaa cctccgcgtg atcaaagccg gtcgatcggc ctcgcagaac
    15001 ccacgcgcgc cgtcctctcc ccttccacct gcctcgatta ctgtgagtga ccgagtaggg
    15061 aggggatccg accatggcac aggaaccgag gatcgacgtc gagatcaacg ccaggaccgt
    15121 cgagagcagc ctggccccgg accagatcga acgcatcgcg agcgcgctcg gcgatccggg
    15181 cgtctggttc gccgccccgc cggtgcgcga gggggaggcg aggcggcccg acgccgtgtg
    15241 ggagctggtc gcggaccagc cgcaccgggg gcacgtggcg accggccgcg cccatgtcca
    15301 cctggccgag gggcgcacgg cgccggtccg gccgctgatc ttcgccgacg gcttcaacta
    15361 cgggcccagc gacctggcct ccatgtggcg gcacttcgac gccccgtacg agccgggcgt
    15421 ccccggcctg ctggaccagg tgctggcgat gggcatcgac gtcgtgctgc tgggcttcga
    15481 ccagcggcag acgtacgtgc aggcgaacgc gggcgtggcg atcacctgcc tgcggcggac
    15541 gctgcaggag cgccagggcg acacgccgct cgtcgtcggc ggcgtcggca cgggcggcat
    15601 gatcacccgg tacgcgctgg cccgtatgga gagcgagggc gtggaccacc agaccgacaa
    15661 gtacttctcc tacgacaccc cgcacctcgg ggcgtggatc ccgctggtgc tgcagcagct
    15721 cgcgtacctg cacgagacga tccagccgcg cctcgacggg gccgggcagg ccgagctgat
    15781 ccgcagcccg gcggcgcagc agctgctgtg ggggtgggtg ccgggcaccg gctactcggg
    15841 cccggtgacc tcctccagcc cgctgcgcaa ggagctgctg gaggacctgc gccgggtcgg
    15901 ccggttcccg atgcggccgt acaagctggg cctggccaac ggcggcggcg acggccgcgg
    15961 gccggacctg ccgcccggca ctccggtgct ggacctgggc gagggcccgc tgcggctggc
    16021 ggccaggatc cagccggacg ggggcgagct ccgcaacgtc ggcgcgatcg gcttcggcga
    16081 gccggtgtgg acgagcgcga cctcgcacgt ggcggccttc gacggcgcgc ccggcggcac
    16141 gctggacgcc ttcggccggg tggcggacgc gatggggctg cccatccagg accgcttccg
    16201 cggcacctgc ttcgtcccgt cggtgagcgc gatcgcgctg gccagggagc cgctggcgtg
    16261 gcagtccgag ctgtacgccg acctgcggga gctgccgaag gacgagacgt tcctcgacgc
    16321 gttctgctgc gacaccggca acggcccgca cggggcggtg tcggccacgc tggcggagtg
    16381 gttcgtgggc cagctcgcgg gctggtaggc gcaccagggc cccaccggcg gggcgccgga
    16441 ccgcggtccg gcgcccccgc gcgggctcag cggctgccgc ggtgcagcac gaggagctgg
    16501 tcgcgggtgg cgttgcggtc gcggtaggcg atggccgccg gggcctcggc gctgtagtgg
    16561 ccgggcaggc gctcgtcggc gctccagttc gcgccgtcga acacggccca ccagaggctc
    16621 tggtcggcgg cgccgcggtg cacgacgtag aggcggtcct tgtagacggt cagggccggg
    16681 ccctcggcgg agaagtggcc gggcaggcgc tcgtcggggc tccaggagga gccgtcccag
    16741 cgggtccacc agagcgcggt gtcgtcgccc gcgccgcggt gcacgcagta gaggtggccg
    16801 cggaagacgg cgagcgccgg gttggagcgg ctggcgtggc gggggaagcg ctggtcctcg
    16861 ctccactggc cgccgtccca ggtggtccac cacaggctgt cgtcgtgggc gccgcggtgc
    16921 acgcaccaca gcttgccgtc gtagccggcg agcgccgggc tgccggcgct gaagtggcgg
    16981 ggcagccggg cgtcctggct ccactgggag ccgtcccagc gggcccacca cagggcggag
    17041 tcctggtcgg cgccgcggtg cacgcagtag agctggtcgt cgtacacggc cagcgccggg
    17101 gcgctcgcgc tgaagtgccg ggggaagcgc tggtcctcgc tccagccctg ctcggcgtcg
    17161 tagacggccc accacagggc ggagtcgccg tcgctgccgc ggtgggcgac gtagagccgg
    17221 tcgcggtact cggcgagcgc cgcgccggag gcggtgaagt ggtcgacgaa gcgctggtcc
    17281 tcgctccagc cctcgccggg ctcgtgcacg gcccaccaca ggcgggcgtc gccggtcggc
    17341 acgccggcca cgcggatcgg gacgagcgag gcgggcgcgg tccacgggga caccaggcgg
    17401 gcgccgtacg ggcgggcgac cgaggcgatc cagcgggcct tgttgcgggc cgaccactcg
    17461 acgaccgggg ccagccagcc gccgagcacc gcgccggcgg tctcgccgat cagggccgcg
    17521 agctcggcgg cccgcacggc ggcctgctcg ttgaggttga cctcgaagcc ccaccagcgg
    17581 gccaccggcc acacctcggc gccgacggcg cggagctcgc tctgcagccg gcgtacccgg
    17641 tcctggtcgc gcgcgtccag ctcgcggatg cggcgctcgc tgtcgcgcct ggccgccagc
    17701 cactcggcct cggccgcggc gcggttggcg aggtcgtcgt cctccagcag ctcggtctcg
    17761 accgcgatgt cgaccgccgc ggcggcgatc gggtcgtcct gcgcctggag cagcggcgcc
    17821 tcggcgtcga tgccgagctc tgagatgtcg gtcctgttct cgtccatatc cagcccccct
    17881 ggaattcgtg ctgcgtatcc gcatgaacct gacatatagt aactgtgcgt gttcgagcgg
    17941 ttacgatagg gttggaagat aggcggtaaa ggccctacga cgccggtttt ctggcggctc
    18001 cagccagcag gaggccgggc agcgggggct cgccgacgag cgtgacggcc tcgtcggcct
    18061 cgggggcgcc gagcgagccg accccgctcc agcgccgccc cgcgctgagc ccggtcgggc
    18121 cggtcaggcc ggggcggcgg ccggcagggt gagcgtgaac accgtgctgc ccggcacgct
    18181 ggccacctcc acccgcccct cgtgcgcggc ggcgaccgcc gacacgatcg ccaggccgag
    18241 cccgctgccc ccggcccgcc tcgaccgcga tccgtccccc cgcgcgaacc gcccgaacac
    18301 gtgcggcagc acgtgcggcg cgatgcccgg cccgtcgtcg gcgacccgca cccgcacctc
    18361 gccgccgtcc gccagcacgg tcgtggtgac ggtggtgccc ggcggcgtgt gggtgcgggc
    18421 gttggccagc aggttggtca gcacctggtg caggcggtcg gcgtcgccga cgaccagggc
    18481 gggctggtcg ggcaggctga ccagccagcg gtgccggggc gcggcggcgt aggcgtcgcc
    18541 gaccgcggtc acgaccagcg gcgacaggtc cagctccacc cgttccagcg ggcggccggc
    18601 gtccaggcgg gccagcagca gcaggtcctc caccagggtt gtcatccggc cggcctcgga
    18661 gctgatgcgg ccgagcgcgt gcgtggtctg cgggccgtgc ggctcgccgc tccgcctggt
    18721 cagctcggcg tagccgacga tggaggcgag cggggtgcgc agctcgtggc tggcgtcggc
    18781 gatgaaccgg cggagccggg tctcgctctc gtgccgcacc gcgaaggcgg tctcgacgtg
    18841 cccgagcatg cggttgagcg cgccgccgac ctgcccgatc tcggtgcgcg gatcggtgtc
    18901 gggctcgggg acgcgggcca ggcgcaccgc gtcgcccgtg gccagcggca gctcggacac
    18961 gcgggcggcg gtggcggcca gccggccgag cggccgcacg gcgtgccgga cgagcagcgt
    19021 gccggcggcg gccgtcagcg ccaccccggc cagcgtcacc gcggcctcca ccatgaccag
    19081 ccgggtcagc gtggactcca cgccgttgag cggcaacccg gtgaccagca cgtcgccgtc
    19141 cggcgccggc cggctcgcca tccggtacgc gccgagccgc cccaggtcga cggtgaccgg
    19201 ccggccggtg acggcggcga ccttcggggg cgcgggcacg tcccggacgg tgccgccgct
    19261 cagcacggcg gccctgtgca cccggccgag ccgcacccgc gccccgaacg tcccctcggc
    19321 ctggcccggg gacaggagga accacacctc ccgcgccgcc tcgggcgcga gcccggcggg
    19381 cggctccgcc gacgcgccgg cggagcggcg ggcggccgag ctgacctgga tgtccagccg
    19441 gtcggtgagg aagtcctcga acagcagggt ggtggcggtg gcgatgaccg cggagacgac
    19501 ggcgagcagc gcgatcgacg agaccacgag cttggtctcc agcgacatgc tgatccggcg
    19561 gctcatccag cgggccgcag cgtgtagccc acgccccgca cggtgtggat catcggcgcc
    19621 cgccgcgcgt cgatcttgcg ccgcaggtac gagatgtaca gctccacgac gttgctctgg
    19681 ccgccgaagt cgtaggccca cacccggtcg aggatctgcg ccttgctgag cacccggccc
    19741 gggttgtgca tgaggaagcg cagcagctcg aactcggtgg gcgtcagctt gacctccgtg
    19801 ccgccgcggc gcacctcgcg ggtctcctgg tcgagcgtga ggtcgccgac gacgagcacg
    19861 gcgtccggcc gcacccgcac cgcccccgag cggcggagca ggccgcgcag ccggatgacg
    19921 acctcctcca ggctgaacgg cttggtgacg tagtcgtcgg cgccggcgcg cagccccgcc
    19981 agccggtcct gcaccgagtc cttggcggtc aggaacagca ccgggacgcc gggcagcacg
    20041 gcgcggaggc gcggcaggag ctcgacgccg tccatgtcgg gcagcatcac gtccaggacg
    20101 atcgcgtcgg ggcggaagcc gcgggccgcg cggatggcct cgccgccgtt gtgcgcgctg
    20161 cggacgtccc aggactcctg ccgcatcacc atggacagca gctccgtcag cgccggctcg
    20221 tcgtccacga cgaggatgtt gatcgggctg ccgtcggggc ggcgcacggg ctcggactgg
    20281 aggttcgggc tggtcgtgtg catgctggaa cgatggcgtg cccggatgaa ggttcgctga
    20341 tgcgggctta tgaatcgcct gtgagttccg ggccgccgac cagcgcgtac gggcagcgga
    20401 agggcccggc ggggatgcgt gcgccgcacc gccccaccgg gcccttccta tccctttaaa
    20461 gcgctctcac agctgccgga gtcacccaga gcgatatccc ccttccccta gaagagcttt
    20521 ccagaccaga cgttggcggc ggaggcgtag acgctgtagg tctcgccgtc gaagtacggc
    20581 gagctgatgt ggtccacgcg gtcgttctcg tcctggtcgt agaaggcgct ggtcacaccg
    20641 ttgaggtaac cggtgcgctt ggcgctgctg tacttgacca gccacgggcc gccgtcggcg
    20701 cccgcggtca tggcgcactt gaggccgacg tgctcctcga tcttcttcgc ggccgagccg
    20761 acggtcttgg ccgtggtcgt gccgtagcac cacttcggcg tgacgccggt gtagggcttg
    20821 ttgccgtcgg gctgcggcgc ctgcgggtag ccgaagacgt agtgcgcctt cttcagcggc
    20881 tggttccagg cgatgccctg gccgccgacg ttgtcgccga ggcggccggc gtcctcgacc
    20941 tccagcccgt ggcgggaggt cgtgctcttc ttgatcgtca cgccgttgta gaccgagacg
    21001 aaggcgtagt cgcggtcgta gtcctcgtag acgctgtagt cgtagtgcac gaacgcctgc
    21061 ttgccgacgt acacgcccca cggggccttg ccctggtagt agccggggac gaagacccag
    21121 ttgtcgagca gctgctc
//
