LOCUS       NZ_JAKRKC020000001     21065 bp    DNA     linear   CON 09-DEC-2024
DEFINITION  Actinomadura luzonensis strain ATCC 31491 Contig00003, whole genome
            shotgun sequence.
ACCESSION   NZ_JAKRKC020000001
VERSION     NZ_JAKRKC020000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinomadura luzonensis
  ORGANISM  Actinomadura luzonensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 6358096)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Genome draft of Actinomadura sp. ATCC 31491
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6358096)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-APR-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
REFERENCE   3  (bases 1 to 6358096)
  AUTHORS   Shi,X. and Du,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-FEB-2022) School of Medicine, Zhejiang University, 866
            Yuhangtang Road, Hangzhou, Zhejiang 310058, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. v1.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 89.6x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022664455.2-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 18:46:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 10,232
            CDSs (total)                      :: 10,155
            Genes (coding)                    :: 10,004
            CDSs (with protein)               :: 10,004
            Genes (RNA)                       :: 77
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 151
            CDSs (without protein)            :: 151
            Pseudo Genes (ambiguous residues) :: 0 of 151
            Pseudo Genes (frameshifted)       :: 36 of 151
            Pseudo Genes (incomplete)         :: 126 of 151
            Pseudo Genes (internal stop)      :: 3 of 151
            Pseudo Genes (multiple problems)  :: 14 of 151
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:31:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1361510
            Orig. end                         :: 1382575
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAKRKC020000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21065
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="3"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21065
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21065
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11065](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11065
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    384..399
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            942..1754
                     /locus_tag="MF672_RS06475"
                     /old_locus_tag="MF672_006475"
     CDS             942..1754
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS06475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_006475"
                     /product="hypothetical protein"
                     /protein_id="WP_242374835.1"
                     /transl_table=11
                     /translation="MTHEVAAEWGLPRTVRRFDLVFAGLFPWLTPLDGEHRALLTRPLP
                     PVAELAAAADASPLARTAPPAPSAAGGRGPSAEAGRLEGWARLLARLLRERVEAEQRDS
                     GYYSLQAPLEAIFPLTAHLMAVHLADHPFPALLPALPVAAATHDLTGLRRTPSPLLDGV
                     RAAMDDWTAAGVVTPATTAGVVTPATTAGVVTPATAPPPVEPGALVTAFWRDDTGVRDD
                     PATAAARFLRRVPPAILARIHDSPPVRLTPLGAYALRRLLLAHNWTTA"
     gene            complement(1744..2631)
                     /locus_tag="MF672_RS06480"
                     /old_locus_tag="MF672_006480"
     CDS             complement(1744..2631)
                     /NRPS_PKS="Domain: Abhydrolase_1 (28-166). E-value:
                     1.1e-12. Score: 40.1. Matches aSDomain:
                     nrpspksdomains_MF672_RS06480_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.5"
                     /locus_tag="MF672_RS06480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006480"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_242374834.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4.6e-18, bitscore:
                     65.1, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 8.7e-10, bitscore: 37.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKTPPLGRTYEVAGRRLALHRSGEGGPAVVFLPGAGLVGLDFL
                     NVHERVAAFTTSVVYDRAGTGWSDPAPLPRRPGEVAGELRELLRAAGVPGPYVLAGHSL
                     GAFYARRYAQLHPADVAGLLLLDPGHEDIASYLPPEMTELNERMKPDPAQLPELTDEQL
                     AAGRAQYAQLYAAWPDAVRDALAEHHLTTWRSSLAETENFETDVYDELRGGGPLPDVPL
                     LVLTAGGDNPYWERFMSRELMRQGLDGIRAMHAAIAASVPRGEQRVLEGGSHQYAHLEQ
                     ADEVVRAVRDLVKR"
     aSDomain        complement(2134..2547)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MF672_RS06480_Abhydrolase_1.1"
                     /evalue="1.10E-12"
                     /label="MF672_RS06480_Abhydrolase_1.1"
                     /locus_tag="MF672_RS06480"
                     /protein_end="166"
                     /protein_start="28"
                     /score="40.1"
                     /tool="antismash"
                     /translation="PAVVFLPGAGLVGLDFLNVHERVAAFTTSVVYDRAGTGWSDPAPL
                     PRRPGEVAGELRELLRAAGVPGPYVLAGHSLGAFYARRYAQLHPADVAGLLLLDPGHED
                     IASYLPPEMTELNERMKPDPAQLPELTDEQLAAG"
     CDS_motif       complement(2305..2349)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MF672_RS06480_0001"
                     /evalue="1.10E-05"
                     /label="NRPS-te1"
                     /locus_tag="MF672_RS06480"
                     /protein_end="109"
                     /protein_start="94"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GPYVLAGHSLGAFYA"
     misc_feature    complement(2689..2703)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.01"
                     /tool="antismash"
     gene            2689..3225
                     /locus_tag="MF672_RS06485"
                     /old_locus_tag="MF672_006485"
     CDS             2689..3225
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891842.1"
                     /locus_tag="MF672_RS06485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006485"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_242374833.1"
                     /transl_table=11
                     /translation="MEALELFAHPVRMRIIHAMSGDRVFTTAALGDLLPDVSKATLYRH
                     VGVLAEAGVLEVAGEERVRGAVERRYRLRRDRAAVDAEMVASVTPEDHRRIFAAAVATL
                     LAEFHAYLDRDGADPVADLVGYRQHALWLNPAELSDLIERLRAAIIPHLTHDPAPDRTR
                     YLLSPILFPIEERRP"
     misc_feature    complement(3280..3295)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            3319..4572
                     /locus_tag="MF672_RS06490"
                     /old_locus_tag="MF672_006490"
     CDS             3319..4572
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038083.1"
                     /locus_tag="MF672_RS06490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006490"
                     /product="CU044_5270 family protein"
                     /protein_id="WP_242374832.1"
                     /transl_table=11
                     /translation="MTLETAEIDDAELIRRSVGDPEQFAALFDAYDLAVPLARPRLYGI
                     ATTLVARHRRQEERLLRALARTGVDPLPEPIADTVVRRVAAQDKERELARALASLSRDD
                     RDVLLLVAWEGRDRLLAAARALDAHQEPSRHHKPHLGRHLGRRLALASALAVAIGAGVI
                     VANDRPHAMPVANVRELGERAARAAYDHDYDDRGQAPNPGQWLYVKQLQAPQSADGGYG
                     VDLSRREIGEEWNSVDGLQTAALFPNGKLLVQGNHPGLSAAELARRPVTPEGLLAKIRQ
                     KLADMHISWTGTDAPPSMDERLFQAVYQIMGTQALPPEVRAALFRGLATIPGVSVNQNA
                     VDADGRQGVAFSYSDGWTRYDLILDPVDFRFLGTYGVTVRDRTVDHTDSPSQFVKAGTP
                     LTLTALLDTKVVDAPGRK"
     gene            complement(4594..6417)
                     /locus_tag="MF672_RS06495"
                     /old_locus_tag="MF672_006495"
     CDS             complement(4594..6417)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544890.1"
                     /locus_tag="MF672_RS06495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006495"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242374831.1"
                     /transl_table=11
                     /translation="MGFLMDGLDAEDYDRTYNDRDLLRRILSYFRPKLGAMVLVATMIV
                     LLSASQAAVPAIGSLAVDAIAAGTIGEVGWLLAAAILVTGALSWVFNYLRQKHSAQVTG
                     DVVLRLREDAFDAVLERDLSFYDETPSGRIVSRVTSDTDDFATVSTLTMDLISQVLMVG
                     FVTALLFARSAQLALMTLLVVPVVVGLALLFRRLARVSTRRAQRSLSRVNANLQETMGG
                     IAVAKNFRQERQVYDEFRPINRQSYQVTLRQGFVFSTIFPVLFTVAGLATVALVQLGGA
                     RVVAGGLTAGDWYLFLQSVSLFWFPLTSIAAFWSQFQQGLSASERVFALIDAPPRVVQT
                     DARQVGRLAGRIEFRGVTFGYDPASPVLRDFDLTIAAGETVALVGHTGAGKSTLSKLIT
                     RFYEFQDGGLFIDGHDIRTLELGAYRRQIGAVPQAPFLFSGTVADNIRYPRPEADDEEV
                     RRAAEAVGGGDWIDALPNGLSTDVGEHGRALSMGQRQLVALARLLVQDPAIVVLDEATA
                     SVDPLTEAQIQEGLDTVLAGRTSIVIAHRLSTIEHVDRIIVLDHGRIVEEGDHATLLER
                     GGRYCEVYNTYFRHQSPNYRAGTGFVAVAGD"
     gene            complement(6417..8249)
                     /locus_tag="MF672_RS06500"
                     /old_locus_tag="MF672_006500"
     CDS             complement(6417..8249)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544889.1"
                     /locus_tag="MF672_RS06500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006500"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242374830.1"
                     /transl_table=11
                     /translation="MTHSNAEFSVSGPRHDRRGPVRWLWSHLRRHPFQLVGFLGGSVVM
                     TTLNAMVPQFTGDAFDAVLGHRGAPLDALGLIALALLAVVLARGVFDLVARLSSEVLAK
                     RLERDARDELYVSLLGKSQTFHNRQRVGDLMARAANDIRQLSIMITPGADLIVDSGLTG
                     VVPLFFIAAIDPRLLLVPGVFAVVFALALRHYMRRLNPVATRMREEFGELNAGLSQAVR
                     GIEVIKVTAQEGQERLRFRANARRYRDSFVRNGLVQARYLPTLLFSAAMAGALWHALAL
                     HGAGAISVGELVAFMGLMGMLGFPTQMSIFTFSLMQIGVVSARRILDIMTADSEIEQRA
                     AGHAAPISGEIVFEDVSFGYDEGGGEPALRGVSFTVRPGETVAIVGETGSGKSTLTKLV
                     PRIYDVTAGRVLVDGVDVREWDLDSLRSQISTIEQDIVLFSRPVRENIAFSLGQRADQE
                     AVAQAAEDAQAAEFIAELDDGYDTVIGERGVTLSGGQRQRLAIARALLTDPAILVLDDS
                     TSAIDSATEDKIQQAIGRILEGRTTLLITHRLSQIRWADKVLLLRRGQVVDFGTHDELI
                     ARSRLYRRVFSHYDEVDTQEDGPAVLAGEQGGAL"
     misc_feature    complement(8282..8297)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.23"
                     /tool="antismash"
     gene            8416..9147
                     /locus_tag="MF672_RS06505"
                     /old_locus_tag="MF672_006505"
     CDS             8416..9147
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS06505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_006505"
                     /product="hypothetical protein"
                     /protein_id="WP_242374829.1"
                     /transl_table=11
                     /translation="MPHHAPTVPRLVVRYLTHHDCGLYVCPLPLAERRTGVTHLVVGPP
                     RDQDLVQMWDDVRVLRADGIRVLAQLDEPLARDYPALRRYLLRHRFDGADLCLPRPAAL
                     AGRLRADLGPGFLLTVTAPATALAGGDPDLDALCADRRTDIAWFTALLFDDHGTPADYE
                     AVVARGLVPAARLVAAFPTSPDNARAGYVPPDRLTAIVRDLLRRHPDLGGVDGWEYYNA
                     LPGGTDAPWLWAELVHAALHP"
     gene            9222..9965
                     /locus_tag="MF672_RS06510"
                     /old_locus_tag="MF672_006510"
     CDS             9222..9965
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019633619.1"
                     /locus_tag="MF672_RS06510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006510"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_242374828.1"
                     /transl_table=11
                     /translation="MSHGERERAPGGIDVTRPSVSRVYDALLGGTENAEADRRMLAQVL
                     LVAPDAHEAAWTNRMFLRRVVRYLAGQCGVRQFLDIGSGLPTQGNVHEIAQATDPRSRV
                     VYVDHDPLVLVHGQALLASDASTVVVEADLRRPVEILTHPQVRRLIDFDWPVGLLLFGI
                     LHHLTDDEDPAGIVSELVEALPSGSYVAVSHFFDPGPAAPDVSRQVATAELLFNRHRWR
                     PHRPALSPRLGTAHETLIGGVACKL"
     misc_feature    9960..9962
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        10001..10270
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MF672_RS06515_Pantocin_Microcin_RRE.1
                     "
                     /evalue="3.80E-17"
                     /identifier="RREFam017.1"
                     /label="MF672_RS06515"
                     /locus_tag="MF672_RS06515"
                     /protein_end="90"
                     /protein_start="0"
                     /score="53.2"
                     /tool="antismash"
                     /translation="MRLPRVKPEHAPHRFGDGTIRLGGVLYGIASEITDDDGCAWAVLN
                     LMDGTRSPAEIAETLHSAFSAVLTRAEAVEIVDTLIASGHVEEAA"
     gene            10001..11065
                     /locus_tag="MF672_RS06515"
                     /old_locus_tag="MF672_006515"
     CDS             10001..11065
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.5"
                     /locus_tag="MF672_RS06515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006515"
                     /product="HesA/MoeB/ThiF family protein"
                     /protein_id="WP_242374827.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 8e-15,
                     bitscore: 53.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 7.8e-45, bitscore: 151.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLPRVKPEHAPHRFGDGTIRLGGVLYGIASEITDDDGCAWAVLN
                     LMDGTRSPAEIAETLHSAFSAVLTRAEAVEIVDTLIASGHVEEAAPGPCAELSPREKDR
                     YSRSKDYFRWVDLHPRDSGWEPQVRLKQARVLVLGLGGTGSHAAWSLAASGVGRLHLVD
                     PDVVELSNLNRQLLYTEADVGRSKADVALARLREVNSDIEITAASATVDGPADLTRLVR
                     GFDVLALCADRPREPDGIQSWANAVCAKAGIPWVSGGYNGPLVSVGVFGPGGPCFACVR
                     AGIPPRPGADYAWPGVTGATAGLSGQLVAYDVVSLVTGLATTPPGYFHGVTLLDPDGHV
                     YARHPARPDCEICS"
     gene            11130..11252
                     /locus_tag="MF672_RS51260"
     CDS             11130..11252
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS51260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_302893169.1"
                     /transl_table=11
                     /translation="MSNTPIPESRQERKPRKKITVRRLDKIEPTAVSPSQGASN"
     gene            11300..11884
                     /locus_tag="MF672_RS06520"
                     /old_locus_tag="MF672_006520"
     CDS             11300..11884
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045158.2"
                     /locus_tag="MF672_RS06520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006520"
                     /product="DUF6879 family protein"
                     /protein_id="WP_242374826.1"
                     /transl_table=11
                     /translation="MSDVLTRLRTAPATRMDATAYGMDFAREFAAASGVIWKLERAQHF
                     DEGDLPSYRAMRDGDWGLAMELAERMRPAFRADNPARLDFRRVRVVEEPLTDYVRWELA
                     LLAMRAEEGENNRVVPAAAVRPYESAGPVPELVLFRPTLLYEVLYDAAGRHVGARRITD
                     PEAVEPCLPVLAGLFARGENLRSYQARVRTM"
     gene            11881..13089
                     /locus_tag="MF672_RS06525"
                     /old_locus_tag="MF672_006525"
     CDS             11881..13089
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS06525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_006525"
                     /product="hypothetical protein"
                     /protein_id="WP_242374825.1"
                     /transl_table=11
                     /translation="MTVAFHRLAFRQDGDEWIVGRVDSGDFVAVPEEGVLAIRLLQDGL
                     DVEQVRARLLHETGADLDVADFVGDLAEAGLVAGIGGRPVPSPPPLRPTLPRLRPRHLR
                     WALHPALHLALLVPIGAGAGCLALRPEIFPGWRAAFFTGHGAAVLLTWAAIAWLTTGLH
                     ELAHLVTARAAGVPARITLGTRLQFLVAQTDVSGVWPAPRRVRVTVYLSGIAVDLALCG
                     AALTWTFFAGPGPVATWLTLVLTLRLAAQLLVFTRTDLYFLLQDATGCRDLYGDGAAYV
                     RDLLSFRRRTRLATLPPRERRAVRLYAAVQGAGTLACLAFAALVTLPLVVTLLARSIQS
                     LLHAADPAAVAEAIVVLALVLVPDVLWARAWWGRHGPRVRRWTALARAALPRLARPFRS
                     VRR"
     gene            complement(13079..14023)
                     /locus_tag="MF672_RS06530"
                     /old_locus_tag="MF672_006530"
     CDS             complement(13079..14023)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852783.1"
                     /locus_tag="MF672_RS06530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006530"
                     /product="polysaccharide lyase family 1 protein"
                     /protein_id="WP_242374824.1"
                     /transl_table=11
                     /translation="MSRTRKLVTGLTAAIMTTAGLAASAPAASAAESAPVGWASQGGGT
                     TGGGSGASTTVSTAAALTSALTSATPVVRVSGTINCSGMLKVGSNKSVIGNAGATIVGC
                     GLNVASASNVIIRNLTFRNWNDDGINVQYSTRVWIDHNSFSNGYDGAVDIKRASDYVTV
                     SWNKFFDHDKTMLLGHSDSNGGEDRGHLRVTYHHNWFNGTNQRHPRVRFGNPVHVYNNL
                     YSNIGSYGVASTMEAGVLVEGNYFENTGDPYHLGEGSSPAGSLVARNNQLVNSGSGQTG
                     GSVKTIPYSYTMDAAANVKSVVSNGAGAGKISV"
     misc_feature    complement(14108..14119)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.99"
                     /tool="antismash"
     misc_feature    14204..14216
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
     gene            14398..14631
                     /locus_tag="MF672_RS06535"
                     /old_locus_tag="MF672_006535"
     CDS             14398..14631
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS06535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_006535"
                     /product="hypothetical protein"
                     /protein_id="WP_242374823.1"
                     /transl_table=11
                     /translation="MATQEQISAARRHIEQLRDQHGGDVRGLIHLIDAGAIKGPAADRL
                     LRDVQSWDQAFRAMFDRALSLLETLRPDGTRS"
     gene            14628..16706
                     /locus_tag="MF672_RS51265"
     CDS             14628..16706
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS51265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="DUF6571 family protein"
                     /protein_id="WP_302893170.1"
                     /transl_table=11
                     /translation="MSPGPATPLSIDPALMTQLIALMKRLAHTVPDVGVQVDKALSPLH
                     LALHGPGTARDLGHRIAAKVPDLQRRLDLMLAAQKVALNTSRSLWADESKWLSTTPEAG
                     AATAKRLATALRTAIRTGTLDPHLLTELQHHQDDPYFALAFATQFPPSDLRQLLTALYR
                     RQTGLATGPDPDALAELDKLSAALSTTLATASRGAGDLQLPKGYVDQLLAHLDTPETAF
                     ALNKLLRTGHFDDPFLREIATKVYDFERAQPPGSLYWRNLMPATQPMNDLPAAYKDPMA
                     AVAAALAHNPRAAQDFLTDPGRKPLDYLMRERVWYEATDSDLGHALEAATTTFRDHDLP
                     PGQSRGYTSALIASWALRFWSNPAVQSNLHDTRQSAGNILAAYTSDLNRLAGRRVSQPP
                     GVSPIPDSDPHLRGVQPYGAMLDHDGVMNVMKWAFDDPVALKTVVAAQGQYSINVLNER
                     AAKVAEQVRSDFERWHRAHPEATTAEINEQRQRILEDRMAGPGGAAFSTDVERLSKTLY
                     IITDAGNIAHIDRADAHDRVFGAFKEAVTSVADLVPGPQGKISSFLFDQAKSAVFGQMS
                     TQQGDAARSQAASTLGQSIDMFTDITADVMMRHGLFGDGEVPARTHPHASTNYPRGSEG
                     DFLDGSRIVLWSQMNHQQRDAYSEWLSLGETGVVFRDPMRAVRDGFKQAGASEEPGP"
     gene            16703..17242
                     /locus_tag="MF672_RS06545"
                     /old_locus_tag="MF672_006545"
     CDS             16703..17242
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MF672_RS06545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MF672_006545"
                     /product="hypothetical protein"
                     /protein_id="WP_242374821.1"
                     /transl_table=11
                     /translation="MRASILAPLLLMAMAMASACTSSPPPDTRPLGNVTASPQECGLIA
                     KRVIIRATGVEMYEASGSERGGPFSYCVVTDPQHDDRGSLLSIQLDNPSALSAEELANT
                     KKHDHGVDLPPGLGPGYTANFDGKNSRNTYAYAWTSDASRLLSVWITPGASGRDHRADA
                     IEFIRQLRPVLLATAK"
     gene            complement(17325..18095)
                     /locus_tag="MF672_RS06550"
                     /old_locus_tag="MF672_006550"
     CDS             complement(17325..18095)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024783.5"
                     /locus_tag="MF672_RS06550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006550"
                     /product="HNH endonuclease"
                     /protein_id="WP_242374820.1"
                     /transl_table=11
                     /translation="MIDNQLGIRKPRGLTAALSILTTYTPGGGRVPYEDEVGSDGLLRY
                     KFQGNPQHYTNAGLRAAFREGVPLIWFFGIQQGVYLPFFPVWIVGVEAEQSQVAVALDE
                     AQRSLPIGGVSSEIERRYSLGITRRRLHQPVFRQRVIQAYESACAMCRLRHRSLLDAAH
                     IIPDRDTRGVPAIANGVSLCKIHHAAYDENILGIRPDYVVEVRADILREIDGPMLKHGL
                     QELHHHALALPRRRADQPDPVLLEERYDRFRTAS"
     gene            complement(18404..18919)
                     /locus_tag="MF672_RS06555"
                     /old_locus_tag="MF672_006555"
     CDS             complement(18404..18919)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037889.5"
                     /locus_tag="MF672_RS06555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006555"
                     /product="HEPN domain-containing protein"
                     /protein_id="WP_242374819.1"
                     /transl_table=11
                     /translation="MHESARAFRLLAHAEFEAFIEDRAQQIVSRAVSEWLAHGNIRPSL
                     LALVAYESSLGWKETTILSASERQKKAPNLTERVEAARKNYLNYVIMQNNGIKEKNLLR
                     ILLPLGVREEDIDEQWLSALEAWATARGELAHKSGKPQRLLDPQVEYVTVQELRDGFRV
                     IDELLEQL"
     gene            complement(19021..20259)
                     /locus_tag="MF672_RS06560"
                     /old_locus_tag="MF672_006560"
     CDS             complement(19021..20259)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015210.5"
                     /locus_tag="MF672_RS06560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006560"
                     /product="DUF262 domain-containing protein"
                     /protein_id="WP_242374818.1"
                     /transl_table=11
                     /translation="MDDQEDLDIRFDHLDTQWGDVEDDEEPVAPDAVSQAVVTDTDWTA
                     ETILSQLRRGNIQLNPRFQRRDAWDLKRKSRFIESLILGLPIPQLVLAEDKRRRGSFLV
                     LDGKQRLLALRQFAEGSSFAANTTEEFRKFSLRGLDVRTDLNRQTLAKMENDAARVEDL
                     NSFLNQTIRTVVVRAWPNEEFLNLVFLRLNTGSVSLSPQELRQALHPGEFTNFLDDHAS
                     ASTSLQRALKLNGPDFRMRDVEILLRYFAFSYYLPDYRGDLKKFLDGTTEKLNQKWLAE
                     ESGIRDAALQCDRAIDCTVAIFGSDAFHRWDRDHYENRFNRAIFDVMTYYFSTPSVRAA
                     AQARAVDVREAFQDLCDVDTEFVQAVQSTTKSINATQYRLQKWGETLAPIVGENQLRIP
                     YIGDDEKIVFKAD"
     gene            complement(20477..20731)
                     /locus_tag="MF672_RS06565"
                     /old_locus_tag="MF672_006565"
     CDS             complement(20477..20731)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888574.1"
                     /locus_tag="MF672_RS06565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MF672_006565"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_242374817.1"
                     /transl_table=11
                     /translation="MTVDQLDPTPIYEQLARIIRDRIKAGDLEERQLVPSESSLQQEHG
                     IARGSVRRAMELLREQGWVVTIQGRGTFVAPREQWPDQR"
     misc_feature    complement(20798..20811)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.62"
                     /tool="antismash"
ORIGIN
        1 ttcgttcgac acccagtgcc ccggcagccg ccgcatccgg gcggtgaagc tctcccgcgc
       61 ctcgcccggc aggtacacca gcaccgagct gtggaacacc acgggcgtcg ccccggcggg
      121 cacggcggcg accaactcct ccacggcctc gttgaggtcg ccccggacga gccgcggcgg
      181 ctcctgcctg gcgacctcga cggcgccgcg cagcctgcgc agccgttccg gctggtccgg
      241 ccagaccagg ctctccagcc accgcacgtc gtcggggtcg cggacgtcga gcgggttcag
      301 gtccaccccg gcccgccaca ccaccaccgg caccccgccc ggcaccccgt ccggcacccc
      361 gccgggcacc ggcccgtcca cgcggcactc cagcgtcacc gggctgtcct ggggcccgat
      421 cagcggcccg tcgccgtacc ggtaccggta ccgatccggg tacaggcaca gccccgccga
      481 cgccccgacc tcgatcagcg ccagcggctg cggcaacgcg gcgagcaccg gcagcagcac
      541 ggcgcaccgg ccgggctcgt tggtctgggt gcgccgctcc gccatgacgc gccgcacccg
      601 ctcccacgcg cccagcgtcc acgtccggaa ggccgggtag tcctcgaccg gcccgcccag
      661 gtagcgcacc gccgcgaaca gcaggttcgg ctgccgctgc cggtacggca ggtcctcgat
      721 cagccgtacc agctcggcgt ccccggccac ccgccgggcc agctcctcgt acacggcgga
      781 ctcgccgcgc gcctccagcc gtccgaagct ccggtacgcc tccgccacac ccatcggccg
      841 ccgcctttcg ccgcctgtga aaatccttcg tgacataacg gatgtgccca ccttcccccc
      901 gcgtaccgcg cggacgcgcc cgccgggtgc atgatccgtg catgacgcac gaggtggcgg
      961 cggagtgggg tctgccgcgc acggtccggc ggttcgacct ggtgttcgcg ggcctgttcc
     1021 cctggctcac gccgctggac ggcgagcacc gcgcgctcct gacccggccg ctgcccccgg
     1081 tcgccgagct ggccgccgcg gccgacgcct cccccctggc acgtacggcc ccgcccgcgc
     1141 cgagcgccgc cgggggacgc ggcccgtccg ccgaggcggg gcggctggag gggtgggcac
     1201 ggctgctggc ccggctgctg cgcgagcggg tcgaggccga gcagcgcgac agcggctact
     1261 actcgctcca ggcgcccctg gaggcgatct tcccgctgac cgcccacctc atggccgtgc
     1321 acctggcgga ccacccgttc ccggcgctgc tccccgccct gcccgtcgcc gccgccacgc
     1381 acgacctcac cggcctgcgc cgcacgccca gccccctgct cgacggcgta cgcgccgcca
     1441 tggacgactg gacggccgcc ggagtcgtca cgcccgcgac gaccgccgga gtcgtcacgc
     1501 ccgcgacgac cgccggagtc gtcacacccg cgacggcccc gcctccggtc gagcccggcg
     1561 ccctggtgac cgccttctgg agggacgaca ccggcgtccg cgacgacccc gcgaccgccg
     1621 ccgcccgctt cctgcgccgc gtcccgcccg ccatcctcgc ccggatccac gacagcccgc
     1681 cggtccggct gaccccgctc ggcgcgtacg ccctccgccg cctcctcctg gcccacaact
     1741 ggactaccgc ttgaccaggt cgcgcaccgc ccgcaccacc tcgtccgcct gctccaggtg
     1801 cgcgtactgg tgcgaaccgc cctccagcac ccgctgctcc ccgcgcggca ccgaggccgc
     1861 gatggccgcg tgcatggccc ggatcccgtc gagcccctgc cgcatgagct cccgcgacat
     1921 gaaccgctcc cagtacgggt tgtcgccccc ggccgtgagc acgagcagcg gcacgtccgg
     1981 cagcgggccg ccgccgcgca gctcgtcgta gacgtcggtc tcgaagttct ccgtctcggc
     2041 gagcgaggag cgccacgtcg tcaggtggtg ctcggcgagc gcgtcgcgca cggcgtccgg
     2101 ccaggcagcg tagagctgcg cgtactgggc gcggccggcc gccagttgct cgtccgtcag
     2161 ctcgggcagc tgggccgggt ccggcttcat ccgctcgttg agctcggtca tctcgggcgg
     2221 caggtacgac gcgatgtcct cgtgcccggg gtcgagcagg agcagcccgg ccacgtccgc
     2281 cgggtggagc tgggcgtagc ggcgggcgta gaacgcgccg agcgagtgcc cggccagcac
     2341 gtacggcccc ggcaccccgg ccgcccgcag cagctcgcgc agctccccgg cgacctcgcc
     2401 cggccggcgc ggcagcggcg ccgggtcgct ccagccggtg cccgcccggt cgtagaccac
     2461 gctcgtggtg aacgcggcga cgcgctcgtg cacgttcagg aagtccagcc cgaccagccc
     2521 ggctcccggc aggaacacca cggcgggccc gccctcgccc gaccggtgga gcgccagccg
     2581 ccgccccgcc acctcgtacg tccgccccag cggcggcgtc ttctcactca tgtccaccta
     2641 ccattctcaa tcgctgagaa cattatcgtg ccatgagacc attaaggaat ggaagcgctc
     2701 gaactcttcg cccaccccgt acgcatgcgc atcatccacg cgatgtccgg cgaccgcgtc
     2761 ttcaccaccg ccgccctggg agacctgctg cccgacgtgt ccaaggcgac cctctaccgc
     2821 cacgtcggcg tgctggccga agccggcgtc ctggaggtgg ccggcgagga acgggtgcgc
     2881 ggcgcggtcg aacgccgcta ccggctgcgc cgcgaccgcg cggccgtgga cgccgagatg
     2941 gtcgcctccg tcacccccga ggaccaccgc cgcatcttcg ccgccgccgt cgcgaccctg
     3001 ctcgccgagt tccacgccta cctcgaccgc gacggcgccg acccggtcgc cgacctcgtc
     3061 ggctaccgcc agcacgccct ctggctgaac ccggccgagc tgtccgacct catcgaacgc
     3121 ctccgcgccg cgatcatccc ccacctcacc cacgacccgg cccccgaccg cacccgctac
     3181 ctcctcagcc ccatcctctt ccccatcgag gaacgccggc cctgaccccg tccccacccg
     3241 agggacgccg gccgccgaga acctgtccac ggggtgcggg agacaacagg gtgaccgacc
     3301 aacccctaag gagggccgtt gaccctcgag acggccgaga tcgacgacgc cgagctgatc
     3361 aggcgatccg tcggcgaccc ggaacagttc gccgccctgt tcgacgcgta cgacctggcg
     3421 gtcccgctgg cccgccccag gctgtacggc atcgccacca cgctcgtcgc ccggcaccgg
     3481 cggcaggagg agcgcctgct ccgcgcgctg gcccggaccg gcgtggaccc cctgcccgag
     3541 cccatcgccg acaccgtggt gcggcgggtc gccgcgcagg acaaggagcg cgagctggcc
     3601 cgggcgctgg cgtcgctgtc gcgcgacgac cgcgacgtgc tcctgctggt ggcgtgggag
     3661 ggccgcgacc gcctcctggc ggccgcccgc gccctcgacg cgcaccagga gccctcgcgg
     3721 caccacaaac cgcacctcgg gcggcacctc gggcggcggc tggcgctcgc gagcgcgctg
     3781 gccgtcgcga tcggcgccgg cgtgatcgtg gcgaacgacc ggccgcacgc gatgccggtc
     3841 gcgaacgtac gggagctcgg cgaacgcgcc gcccgagccg cctacgacca cgactacgac
     3901 gaccgcggac aggcgccgaa ccccggccag tggctgtacg tcaagcaact ccaggcccct
     3961 cagtccgcgg acggcggcta cggcgtggac ctgtccaggc gcgagatcgg ggaggagtgg
     4021 aacagcgtgg acggcctcca gaccgcggcc ctgttcccca acggcaagct cctggtacag
     4081 ggcaaccacc caggactgag cgcggccgag ctggcccgcc ggccggtcac tccggaagga
     4141 ctgctcgcga agatccgcca gaagctggcg gacatgcaca tctcgtggac gggaaccgat
     4201 gcgccgccct cgatggatga gcggctcttc caggccgtct accagatcat gggcacccag
     4261 gcgctgcccc cggaggtgcg ggcggcactg ttccgcggcc tcgccaccat ccccggggtg
     4321 agcgtcaacc agaacgccgt ggacgccgac ggccggcagg gcgtcgcgtt cagctacagc
     4381 gacggatgga cccgctacga cctcatcctg gacccggtgg acttccgctt cctcggcacg
     4441 tacggggtga ccgtccggga ccgcaccgtc gaccacaccg acagccccag ccagttcgtc
     4501 aaggccggca cacccctcac cctcaccgcc ctgctggaca ccaaggtggt ggacgcccca
     4561 ggccggaaat gacctgccga cggggccggc ggctcagtct ccggcgaccg cgacgaaccc
     4621 cgtccccgcc cggtagttcg gcgactggtg ccggaagtag gtgttgtaca cctcgcaata
     4681 cctcccgccc cgctccagca gcgtcgcgtg gtcgccttcc tccacgatcc gcccgtggtc
     4741 gagcacgatg atgcggtcga cgtgctcgat cgtggacagc cggtgcgcga tgacgatcga
     4801 cgtgcgcccg gccagcacgg tgtcgaggcc ctcctggatc tgcgcctcgg tcagcgggtc
     4861 gacgctggcg gtggcctcgt ccaggacgac gatcgccggg tcctggacga gcagccgggc
     4921 gagcgcgacg agctgccgct gccccatgga cagcgcccgc ccgtgctcgc cgacgtcggt
     4981 gctcaggccg ttcggcaggg cgtcgatcca gtcgccgccg cccaccgcct cggcggcgcg
     5041 ccgcacctcc tcgtcgtccg cctcgggacg cgggtagcgg atgttgtcgg ccaccgtgcc
     5101 gctgaacagg aacggggcct gcggcaccgc cccgatctgc cgccggtagg cgcccagctc
     5161 cagggtgcgg atgtcgtgcc cgtcgatgaa caggccgccg tcctggaact cgtagaagcg
     5221 ggtgatcagc ttgctgagcg tcgacttacc cgccccggtg tggccgacga gcgcgaccgt
     5281 ctccccggcc gcgatggtca ggtcaaaatc gcgcagcacg gggctggccg ggtcgtagcc
     5341 gaacgtgacg ccgcggaact cgatgcgtcc ggccagcctg ccgacctgcc gcgcgtcggt
     5401 ctgcaccacc cggggcggcg cgtcgatcag cgcgaagacc cgctcgctgg ccgacagccc
     5461 ctgctggaac tgcgaccaga acgccgcgat cgacgtcagc gggaaccaga acagcgacac
     5521 gctctgcagg aacaggtacc agtcgccggc cgtcagcccg cccgccacca cccgcgcccc
     5581 gccgagctgc acgagcgcca ccgtggcgag gcccgccacc gtgaacagca cggggaagat
     5641 cgtggagaag acgaacccct gccgcagcgt cacctggtag ctctgccggt tgatgggccg
     5701 gaactcgtcg tagacctgcc gctcctgccg gaagttcttg gccacggcga tgccgcccat
     5761 ggtctcctgc aggttggcgt tgacccggct cagcgagcgc tgcgcgcgcc gggtgctgac
     5821 tctggccagc cgccggaaca gcagcgccag cccgaccacg accggcacca cgagcagcgt
     5881 catcagcgcg agctgcgcgc tgcgcgcgaa cagcagcgcc gtgacgaagc cgaccatcag
     5941 tacctggctg atcaggtcca tcgtcagcgt ggagacggtg gcgaagtcgt cggtgtcgga
     6001 ggtgacgcgg ctgacgatgc ggccggaggg cgtctcgtcg tagaacgaca ggtcgcgctc
     6061 cagcaccgcg tcgaaggcgt cctcgcgcag ccgcagcacg acgtcgccgg tgacctgcgc
     6121 gctgtgtttc tggcgcaggt agttgaagac ccacgacagc gcgccggtga ccaggatcgc
     6181 ggcggcgagc agccagccga cctcgccgat ggtgccggcc gcgatggcgt cgacggcgag
     6241 gctgccgatc gccgggacgg ccgcctggct cgccgacagc agcacgatca tcgtggcgac
     6301 cagcaccatc gcgcccagct tcggccggaa gtaggacagg atgcggcgca gcaggtcgcg
     6361 gtcgttgtag gtgcggtcgt agtcctcggc gtcgaggccg tccatcagga agcccatcag
     6421 agcgcccctc cctgctcgcc cgccagcacg gcgggaccgt cctcctgcgt gtcgacctcg
     6481 tcgtagtggg agaacacccg ccggtagagc cggctgcgcg cgatcagctc gtcgtgcgtg
     6541 ccgaagtcga cgacctgccc gcgccgcagc agcagcacct tgtcggccca gcggatctgc
     6601 gagagccggt gcgtgatcag caacgtcgtg cgcccctcca ggatgcgccc gatggcctgc
     6661 tggatcttgt cctcggtggc cgagtcgatg gcgctggtgg agtcgtcgag gacgaggatc
     6721 gccgggtcgg tgagcagcgc ccgcgcgatg gccagccgct gccgctgccc gccggagagc
     6781 gtgacgccgc gctcgccgat cacggtgtcg tagccgtcgt ccagctccgc gatgaactcg
     6841 gcggcctgcg cgtcctcggc ggcctgcgcc accgcctcct ggtcggcgcg ctggcccagg
     6901 ctgaacgcga tgttctccct gaccggccgg gagaacagca cgatgtcctg ctcgatggtg
     6961 gagatctggg agcgcagcga gtcgaggtcc cactcgcgca cgtcgacgcc gtcgaccagg
     7021 acgcgcccgg cggtgacgtc gtagatgcgc ggcacgagct tggtgagcgt gctcttgccc
     7081 gacccggtct cgccgacgat cgcgaccgtc tcgcccggcc gcacggtgaa cgacacgccg
     7141 cgcagcgccg gctcgccgcc gccctcgtcg tagccgaagc tgacgtcctc gaagacgatc
     7201 tcgccgctga tgggcgcggc gtgcccggcg gcgcgctgct cgatctcgct gtcggcggtc
     7261 atgatgtcga ggatgcggcg cgcggagacg acgccgatct gcatgagcga gaacgtgaag
     7321 atcgacatct gggtggggaa cccgagcatg cccatgagcc ccatgaacgc gaccagctcg
     7381 cccacgctga tcgcgccggc gccgtggagg gcgagggcgt gccagagcgc gcccgccatc
     7441 gcggccgaga acagcagggt cggcaggtag cgggcctgca ccagcccgtt gcgcacgaac
     7501 gagtcgcggt agcgccgcgc gttggcccgg aaccgcagcc gttcctgccc ctcctgcgcg
     7561 gtcaccttga tcacctcgat gccgcgcacg gcctggctga gcccggcgtt gagctcgccg
     7621 aactcctccc gcatgcgcgt cgccaccggg ttgagccggc gcatgtagtg ccgcagcgcg
     7681 agcgcgaaca ccaccgcgaa caccccgggc accagcagca gccgcgggtc gatggccgcg
     7741 atgaagaaca gcgggacgac gccggtcagc cccgagtcga cgatgaggtc ggcccccggc
     7801 gtgatcatga tggagagctg gcggatgtcg ttggcggcgc gggccatgag gtcgccgacc
     7861 cgctgccggt tgtggaaggt ctggctcttg ccgagcaggc tcacgtacag ctcgtcgcgc
     7921 gcgtcgcgtt cgagccgctt ggccagcacc tcgctggaca gccgcgccac caggtcgaac
     7981 acgccgcgcg cgagcacgac cgcgagcagc gcgagcgcga tcagcccgag cgcgtccagc
     8041 ggcgcgcccc ggtgcccgag cacggcgtcg aaggcgtcgc cggtgaactg cggcaccatg
     8101 gcgttgagcg tggtcatcac gaccgacccg ccgaggaacc cgacgagctg gaacggatgc
     8161 cgccgcaggt gcgaccagag ccaccgcacc ggcccgcgcc ggtcgtgccg cggcccggac
     8221 acggagaact ccgcgttgct gtgtgtcact ggcaccgccc ccgaccgcgg ctcgttggac
     8281 ttcgaacctg ctttctatca ggggcggccg acagtttccc aacgggtttt acccgtccca
     8341 gaagtccagg tcttgtcact ttgggtatca ataagggata cgaagcgtaa cctccctcgc
     8401 ccgaaggatc cgcccttgcc ccaccacgca ccgaccgtcc cccgcctcgt cgtgcgctac
     8461 ctgacgcacc acgactgcgg gctctacgtc tgcccgctcc ccctggccga gcgccgcacc
     8521 ggcgtcaccc atctggtggt cggcccgccc cgcgaccagg acctcgtcca gatgtgggac
     8581 gacgtccgcg ttctgcgggc cgacgggatc cgcgtcctcg cccagctcga cgagcccctc
     8641 gcccgggact acccggccct gcgccgctac ctcctgcggc accgcttcga cggcgccgac
     8701 ctctgcctcc cccgccccgc cgccctggcc ggccgcctgc gtgccgacct cggccccggc
     8761 ttcctcctca cggtgacggc ccccgccacc gccctggccg gcggcgaccc cgacctcgac
     8821 gcgctgtgcg cggaccgccg tacggacatc gcctggttca ccgccctgct gttcgacgac
     8881 cacggcaccc cggccgacta cgaggccgtc gtcgcccgcg gcctcgtccc cgccgcgcgg
     8941 ctggtcgcgg ccttccccac cagcccggac aacgcccgcg ccggctacgt cccgccggac
     9001 cggctcaccg ccatcgtccg cgacctgctg cgccgccacc ccgacctggg cggcgtggac
     9061 ggctgggagt actacaacgc cctccccggc ggcacggacg ccccctggct ctgggccgag
     9121 ctcgtccacg ccgctctgca cccgtgaggc gtaccctgtc cctcgttcct ccgcccctcg
     9181 tggggacggg cccctgtcac cacctcgtga aggagccacc tatgtcgcac ggcgaacgcg
     9241 agcgagctcc aggcgggatc gacgtcacca ggcccagcgt gtccagggtc tacgacgccc
     9301 tgctcggcgg caccgagaac gccgaggccg atcgccgcat gctggcccag gtcctgctcg
     9361 tcgcccccga cgcccacgag gcggcctgga cgaaccgcat gttcctgcgc cgcgtggtgc
     9421 gctacctggc cgggcagtgc ggcgtccgcc agttcctcga catcggctcc ggcctgccga
     9481 cacagggcaa cgtgcacgag atcgcgcagg ccacggaccc gcgctcccgc gtcgtctacg
     9541 tggaccacga cccgctcgtg ctggtgcacg ggcaggcgct cctggcctcc gacgccagca
     9601 ccgtcgtggt cgaggccgac ctccgccggc cggtcgagat actgacgcac ccgcaggtcc
     9661 ggcggctgat cgacttcgac tggccggtcg ggctgctgct gttcggcatc ctgcaccacc
     9721 tcacggacga cgaggacccg gcgggcatcg tctccgagct ggtggaggcc ctgccctcgg
     9781 gcagctacgt cgccgtctcc cacttcttcg acccgggccc ggccgccccg gacgtgagca
     9841 ggcaggtggc caccgccgag ctgctgttca accggcaccg atggagaccg caccggccgg
     9901 cgctctcccc gcgcctgggc accgcgcacg agacattgat cggcggcgtc gcgtgcaaat
     9961 tatgattgac gccggccagg agaatgtcca ccatcggtga atgcgcctgc cccgcgtcaa
    10021 acccgaacac gccccgcacc gattcggcga cggcacaatc cggctcggcg gggtcctgta
    10081 cggaatcgcg tcggagatca cggacgacga cggctgcgcg tgggccgtcc tcaatctgat
    10141 ggacggcacc cgctcccccg cggaaatagc ggaaaccctg cattccgctt tctccgccgt
    10201 cctgacccgt gcggaggccg tggaaatcgt cgacacgctg atcgcctccg gtcacgtgga
    10261 agaggccgcc ccgggcccgt gcgcggaatt gagcccgcgc gagaaggacc ggtacagccg
    10321 cagcaaggac tatttccgct gggtggacct ccatccgcgc gacagcggct gggagccgca
    10381 ggtgcggctg aaacaggcca gggtcctggt gctgggcctg ggcggcaccg gcagccacgc
    10441 ggcctggtcg ctcgccgcct cgggcgtggg ccggctgcac ctggtggacc ccgacgtcgt
    10501 ggagctgtcc aacctcaacc ggcagctcct ctacaccgag gcggacgtgg gccggagcaa
    10561 ggccgacgtc gctctcgccc ggctgcgcga ggtcaactcc gacatcgaga tcaccgccgc
    10621 gagcgccacc gtggacggcc cggcggacct gacccggctg gtccgcggat tcgacgtcct
    10681 ggcgctctgc gccgaccgtc cgcgcgagcc ggacggcatt cagagctggg ccaacgcggt
    10741 ctgcgcgaaa gccggaattc cgtgggtgag cggcggttac aacggcccgc tggtcagcgt
    10801 cggggtattc ggcccgggcg gtccgtgttt cgcctgcgtc cgggccggaa ttccgccgcg
    10861 gccgggggcc gactacgcct ggcccggcgt gacgggcgcg acggcggggc tgtccggaca
    10921 actcgtcgcc tacgatgtcg tttcattggt caccgggctg gcgaccacgc ctcccggtta
    10981 ttttcacgga gtgacgctgc tcgacccgga cgggcatgtc tacgcccgcc atccggcgcg
    11041 cccggattgc gaaatctgct cttgatgaat gcgccgttgt ttcgtaccgt tccccttgcc
    11101 cgttccgaat tcgatcggta aggagtgtca tgagcaacac cccaattccg gaaagccggc
    11161 aggagcggaa accgcgtaag aagatcaccg tacgccggct cgacaagatc gaaccgaccg
    11221 cggtatcgcc cagccagggc gcctccaact gatccaggtg cgggcggggc ttcccctgcc
    11281 cgcaccccaa gggggcctga tgagtgatgt tctgacccgt ctgcgcaccg cgccggccac
    11341 ccggatggac gcgaccgcgt acggaatgga cttcgccagg gagttcgcgg ccgcgagcgg
    11401 cgtgatctgg aagctcgaac gcgcccagca cttcgacgag ggcgacctgc ccagctaccg
    11461 ggcgatgcgc gacggcgact ggggcctggc gatggagctg gccgagcgca tgcgtcccgc
    11521 gttccgcgcc gacaaccccg cgcggctcga cttccggcgc gtccgcgtcg tggaggagcc
    11581 gctcaccgac tacgtccgct gggagctggc gttgctcgcg atgcgggccg aggagggcga
    11641 gaacaaccgg gtggtgccgg ccgcggcggt gcgcccgtac gagtcggcgg gcccggtgcc
    11701 cgagctggtc ctgttccgcc cgaccctgct ctacgaggtg ctctacgacg ccgccggccg
    11761 gcacgtcggc gcccgccgga tcaccgaccc cgaggccgtc gagccctgcc tgcccgtgct
    11821 cgccggcctg ttcgcgcggg gcgagaacct gcgctcctac caggccaggg tgaggacgat
    11881 gtgacggtcg ccttccaccg gctcgccttc cgccaggacg gcgacgagtg gatcgtcggc
    11941 cgggtggact cgggcgactt cgtggccgtc cccgaggaag gcgtcctggc catccgcctg
    12001 ctccaggacg gcctggacgt cgagcaggtc cgggcccgcc tgctccacga gaccggcgcc
    12061 gacctcgacg tggcggactt cgtcggcgac ctggcggagg cgggcctggt cgccgggatc
    12121 ggcggtcgcc ccgtcccgag ccccccgccg ctccgcccca ccctcccccg cctccggccc
    12181 cgccacctgc gctgggccct gcatccggcg ctgcacctgg ccctgctcgt gccgatcggg
    12241 gcgggagccg gctgcctcgc gctccgcccc gagatcttcc ccggctggcg ggccgccttc
    12301 ttcaccggcc acggcgccgc cgtcctgctg acctgggccg cgatcgcctg gctcaccacc
    12361 ggcctgcacg agctggcgca cctggtcacc gcccgcgccg ccggggtgcc cgcgcggatc
    12421 acgctcggca cccgcctgca gttcctggtc gcccagaccg acgtgtccgg ggtgtggccg
    12481 gcgccccggc gggtccgcgt caccgtctac ctgtccggca tcgccgtgga cctggcactc
    12541 tgcggcgccg ccctgacctg gacgttcttc gccggccccg gcccggtcgc cacctggctc
    12601 acgctcgtcc tgacgctgcg gctggccgcg caactgctgg tgttcacccg tacggacctg
    12661 tacttcctgc tccaggacgc gaccggctgc cgcgacctgt acggcgacgg cgccgcctac
    12721 gtccgcgacc tgctgtcatt ccggcggcgg acccgcctcg ccacgctgcc gccccgcgaa
    12781 cgccgcgccg tccgcctcta cgcggccgtc cagggagccg ggacgctcgc ctgcctggcc
    12841 ttcgcggcgc tggtgacgct gccgctggtg gtcacgctgc tcgcccgttc gatccagagc
    12901 ctgctccacg ccgcggaccc ggcggccgtg gcggaggcga tcgtcgtgct cgcgctggtc
    12961 ctcgtacccg acgtgttgtg ggcccgcgcc tggtggggca ggcacgggcc ccgcgtccgg
    13021 cgctggacgg cactcgcccg cgccgcgctg ccacgcctcg cgcggccatt ccggagcgtc
    13081 agacgctgat cttccccgcg cccgcgccgt tgctcacgac cgacttgacg ttcgccgccg
    13141 cgtccatggt gtacgagtac gggatcgtct tgacgctgcc gcccgtctgc ccgctgcccg
    13201 agttgacgag ctggttgttg cgcgccacga ggctgcccgc cggggagctg ccctcgccca
    13261 ggtggtacgg gtcgccggtg ttctcgaagt agttcccctc gaccagcacg ccggcctcca
    13321 tcgtcgaggc gacgccgtac gagccgatgt tggagtagag gttgttgtag acgtgcaccg
    13381 ggttgccgaa gcgcacccgc gggtgccgct ggttggtccc gttgaaccag ttgtggtggt
    13441 acgtcacccg caggtgcccg cggtcctcgc cgccgttgct gtcgctgtgg ccgagcagca
    13501 tcgtcttgtc gtggtcgaag aacttgttcc acgagacggt gacgtagtcg ctggcccgct
    13561 tgatgtcgac cgctccgtcg tagccgttgc tgaagctgtt gtggtcgatc cacacccgcg
    13621 tcgagtactg gacgttgatg ccgtcgtcgt tccagttgcg gaaggtcagg ttccggatga
    13681 tgacgttgga ggcgctggcg acgttcagcc cgcatccgac gatcgtcgcg ccggcgttgc
    13741 cgatgacgga cttgttcgag ccgaccttca gcatgcctga gcagttgatg gtcccggaga
    13801 cccggaccac gggcgtcgcg gacgtcagag cgctggtgag cgcggcggcc gtgctcacgg
    13861 tggtcgaggc cccgctgccg cccccggtcg tcccgccgcc ctggctggcc cagccgacgg
    13921 gcgcgctctc ggccgccgag gcggcgggcg cggacgcggc cagccccgcc gtcgtcatga
    13981 tcgcggcggt gagtcctgtg acgagcttgc gcgtacgtga catgatctgt gctcctcccg
    14041 atcgttctcc tgatcgccgt tcacatacat ggacaccgcc catgagagcg gacgccgagg
    14101 agcataggaa agcgctttcc cctcgtcaat gcccccgccc gcccgtttca tcccgccatg
    14161 gccgtcttgc caggccagcc cctaacaact cacttttcgc ctggtgaaac tttcacgtcc
    14221 accgcccgaa cccctttgtg acgccgaaaa ccgaacccca ccgcgtcctt ttactgctat
    14281 gacccggaat ccgacatgcc atttgcggac gccaccatga aagacgtcat gcggcccgcc
    14341 tcacctgggt actcttcgcc tggtcaccgc ccgccgacca gctccgaagg acccaggatg
    14401 gcgacacagg agcaaatctc ggccgcccgc cggcacatcg agcagctgcg cgaccagcac
    14461 ggcggcgacg tccgcggcct gatccacctc atcgacgcgg gcgcgatcaa aggccccgcc
    14521 gccgaccgcc tgctccgcga cgtccagagc tgggaccagg cgttccgcgc catgttcgac
    14581 cgcgccctga gcctcctcga aaccctccgc ccggacggca cccgctcatg agcccaggac
    14641 cggccactcc cctcagcatc gacccggcgc tgatgaccca gctcatcgcg ctgatgaagc
    14701 gcctcgcgca caccgtcccc gacgtcggcg tccaggtcga caaggccctg agcccgctcc
    14761 acctcgccct ccacggcccc ggcacggccc gcgacctcgg ccaccggatc gccgccaagg
    14821 tccccgacct gcaacgccgc ctcgacctga tgctcgccgc ccagaaggtc gccctgaaca
    14881 cctcccgctc cctctgggcc gacgagtcca agtggctctc cacgaccccg gaagccggcg
    14941 ccgcaaccgc gaaacgcctg gccaccgccc tccgcaccgc catcagaacc ggcaccctcg
    15001 acccccacct cctcaccgag ctccagcacc accaggacga cccgtacttc gccctggcct
    15061 tcgccaccca gttccccccg agcgacctgc gccaactcct caccgcgctc taccgccgcc
    15121 agaccggcct cgccaccggc cccgacccgg acgccctggc cgaactggac aaactctccg
    15181 ccgccctcag caccaccctc gccaccgcct cccgaggcgc cggcgacctg caactcccca
    15241 agggctacgt cgaccagctc ctcgcccacc tcgacacccc cgagaccgcc ttcgccctca
    15301 acaaactcct ccgcaccggc cacttcgacg acccgttcct ccgcgagatc gccaccaagg
    15361 tctacgactt cgaacgcgcc cagccgcccg gctccctcta ctggcgcaac ctgatgcccg
    15421 ccacccagcc catgaacgac ctcccggccg cgtacaagga cccgatggcc gccgtcgccg
    15481 ccgccctcgc ccacaacccc cgcgccgccc aggacttcct caccgacccc ggccgcaaac
    15541 ccctcgacta cctgatgcgc gaacgcgtct ggtacgaggc cacggacagc gacctcggcc
    15601 acgccctgga agccgccacc accaccttcc gcgaccacga cctcccgccg ggccagtccc
    15661 gcggctacac atccgccctg attgcctcct gggcgctgcg cttctggtcc aacccagctg
    15721 tccagtccaa cctccacgac acccggcaga gcgcaggcaa catcctcgcc gcgtacacaa
    15781 gcgacctgaa ccgtctcgcg ggtcgacgag tgtcccaacc acccggtgtg tccccgattc
    15841 ctgactccga cccccacttg cgaggcgtgc agccctacgg cgcgatgttg gaccacgacg
    15901 gcgtcatgaa cgtgatgaag tgggccttcg acgacccggt ggcgttgaag acagtagtgg
    15961 cggcccaagg gcagtacagc atcaacgtgc tgaacgagcg ggcagcgaag gtcgccgagc
    16021 aggtgcgctc ggacttcgag cggtggcatc gagcccatcc tgaggcgacc accgccgaga
    16081 tcaacgagca gcgtcagagg atcctggagg accgcatggc agggccgggc ggggccgcct
    16141 tcagcacgga cgtggagaga ctgagcaaga ccttgtacat catcaccgac gcggggaaca
    16201 tcgcccacat cgacagggcg gacgcgcacg atcgcgtgtt cggcgcgttc aaggaagccg
    16261 tgacgagcgt ggcagatctc gttccagggc ctcagggcaa gatcagcagc ttccttttcg
    16321 accaggccaa atcggcggtg tttggacaga tgtcaaccca acagggggac gcggcgcgta
    16381 gccaggcggc ctccacgctc ggccagagca tcgacatgtt caccgacatc acggcggacg
    16441 tcatgatgcg gcacggcctc ttcggggacg gcgaggttcc cgcccgcacc caccctcacg
    16501 cgtccaccaa ctaccctcgc ggctcagagg gggatttcct ggatggcagc aggatcgtgc
    16561 tgtggagcca gatgaaccac cagcagcgcg acgcctactc ggaatggctc agcctcggcg
    16621 agacgggagt ggtcttccgc gaccccatga gagcggtcag agacggcttc aagcaagcag
    16681 gcgcctccga ggagcccggc ccatgagagc ctccatcctc gcgccccttc tgctcatggc
    16741 tatggccatg gcctcggcct gcacctcctc cccaccaccc gacacccgcc ccttgggcaa
    16801 cgtgacagcg agccctcaag agtgcggcct catcgcgaag cgggtcatca tccgcgcgac
    16861 cggcgtcgag atgtacgagg cttccggcag cgagcgagga ggaccgttct cctactgcgt
    16921 ggtgaccgac ccgcagcacg acgatcgcgg ctccctcctt tccattcagc tcgacaaccc
    16981 gtccgcccta tccgccgagg agttggcgaa caccaagaag catgaccacg gtgtggacct
    17041 cccacctggc ctcggccccg gttatacggc caattttgat ggcaagaaca gtcgcaacac
    17101 gtacgcctac gcgtggacct cggacgccag ccgtcttctg tccgtctgga taaccccggg
    17161 agcttcaggc cgggatcacc gggcggatgc cattgagttc atccgccagc tcagacctgt
    17221 cctcctggcc acggctaagt aacacagcta tggacgctcc acacccaacc gccggtgact
    17281 ggctgggcat gacgctgttc accggttccc cctcggctgc ggactcaact ggcagttcga
    17341 aagcggtcgt agcgttcctc cagaagtact gggtccggtt gatcagctcg cctccgagga
    17401 agagctagcg cgtggtggtg caattcttga agtccgtgct tgagcatagg tccatcgatc
    17461 tcgcgtagga tgtctgcacg tacttcgacg acatagtcag gccgaattcc gagaatgttc
    17521 tcgtcgtacg ctgcatggtg gattttacac aaagaaacac cgttggctat agctggaaca
    17581 cctcgggtgt cgcggtcagg aatgatgtga gccgcatcaa ggagcgatcg gtgccggagc
    17641 cggcacattg cacacgcgct ctcatacgcc tggatgaccc gctgtcgaaa gaccggttgg
    17701 tgcagtcgtc gcctcgtgat tcctagagag taccgacgtt cgatctcgct gctcacgcct
    17761 ccgatgggca gggatcgttg cgcttcatcc aaggccaccg ccacctgtga ttgctcagcc
    17821 tcgacgccga cgatccagac aggaaagaaa ggcaggtata ccccttgctg tattccgaag
    17881 aaccatatga gcggcacccc ctcgcgaaag gccgctcgta gcccagcgtt ggtgtagtgc
    17941 tgcgggttgc cttggaactt gtagcgcagc aggccgtcgc ttcccacctc gtcctcgtaa
    18001 ggcacccgcc cgcctccagg cgtgtaggtg gtcaagatcg acagcgcggc ggtcagacct
    18061 ctgggtttcc tgatacctag ctgattgtcg atcaagggga acactcgtcc ctcgaacctg
    18121 aagccaagca actcgtcacg gcggacaatt ggggtgtcag gcgtacatct ctgccgaagc
    18181 caagccatgg ccgccgctcg tacccgagcg tccaagtcat cggggggtgt tgtgagcaca
    18241 aggcactttt acacccttag ccagcctgcc tgctagggca tctggctacg cagcacgagg
    18301 ccaccaactc aggcgggtgt cactcgcaat cgaaacagag gcgtcaggac tcgatggtcg
    18361 ccctcgatgg gccgttcaga ccagagagat agtgtgagca gacctacaac tgctctagca
    18421 gttcgtcaat caccctaaaa ccatcccgca attcttgcac cgtcacatac tctacttgcg
    18481 gatcgagcaa tcgctgaggc ttccccgatt tgtgcgccag ctctcctcta gccgtcgccc
    18541 acgcttcgag agcactcaac cactgctcgt cgatatcctc ctcccgaaca cccagcggga
    18601 ggaggatcct cagcaggttc ttctccttga tgccgttgtt ctgcatgatc acatagttca
    18661 gatagttctt gcgagcggct tcaacccgtt cggtgagatt aggcgccttt ttctgcctct
    18721 cgctagcaga aaggatggtc gtctccttcc accccaagga gctctcatat gcgaccaggg
    18781 caagtaggct cggcctgata ttgccatgcg cgagccattc acttacagcc cgagaaacga
    18841 tctgctgcgc ccggtcctct atgaatgcct cgaactcggc atgagccagg aggcggaacg
    18901 ctctcgcgct ctcatgcacg cgaaccgtat aaagccccgt cgggtcgaac tcctcgggga
    18961 ggagattact ccgtaactct agtaagcgtg catagagagt ctggaaacga ggagaaggca
    19021 tcaatccgcc ttgaatacta tcttctcatc gtcgccgata tatgggatcc gcaactggtt
    19081 ctcgccaacg atcggagcaa gcgtttcgcc ccacttctga agtcggtatt gagttgcgtt
    19141 aatggatttc gtagtactct gcaccgcttg cacgaattcc gtgtccacat cgcagagatc
    19201 ctgaaatgcc tcacggacgt cgacagcccg tgcctgcgca gccgccctaa ccgaaggtgt
    19261 cgagaagtag taggtcatca catcgaagat tgccctattg aagcggttct cgtagtgatc
    19321 cctatcccac cgatgaaagg catccgagcc gaaaatggct accgtacagt cgattgcccg
    19381 atcacactgc agggctgcat cccgtatgcc ggactcttca gcgagccact tctggttaag
    19441 cttctcggtc gtcccgtcaa gaaacttctt caagtcgccg cgatagtcag gcagataata
    19501 ggagaaggca aagtacctca acaggatctc gacatcacgc attcgaaagt caggcccgtt
    19561 gagcttgagc gccctctgca aagaggtgct ggcgctcgca tgatcgtcaa ggaagttggt
    19621 gaactcacca gggtgaagcg cctgccggag ttcctgcgga gagaggctta cgctgccagt
    19681 gttcaggcgc aggaagacca gattgaggaa ctcctcattc ggccatgccc gcaccacgac
    19741 cgtacggatg gtctggttga ggaacgagtt caagtcctcg actctggccg catcgttttc
    19801 catcttcgcc agagtctgcc tgttgagatc tgtccggacg tcaagacctc taagactgaa
    19861 cttacggaac tcctctgttg tgttcgccgc aaaggatgat ccctctgcga actgccgcag
    19921 cgcaagaagc cgctgcttgc cgtcgagaac gagaaaagaa cctcgtcgcc tcttatcctc
    19981 agcaagaacc aactgtggta tgggaaggcc aaggattagc gattcgatga accggctctt
    20041 ccgcttgaga tcccaggcat ctctccgctg aaaccgcggg ttgagctgaa tgttacctcg
    20101 gcgtagctga ctaagaattg tttcggctgt ccagtcggtg tcggttacta ctgcttggga
    20161 gacagcatcg ggcgccaccg gttcctcgtc gtcctcgaca tctccccact gggtgtcaag
    20221 gtggtcgaat ctgatgtcca gatcctcttg gtcatccatg tgctcaccct ccagatctgg
    20281 gcagtctacc tccgtacggc acactagctg caacagtaga gtattgaaga aatttcctcc
    20341 caaacagttg attttacact tccgtccgcg tctgaccgct taatgccgct ccttcccaat
    20401 agacggcctt gcttacaggg aacctagggc cagcgaggcg ggaccaggct catgggcgcc
    20461 ctctccagtt caccggtcag cgctggtcgg gccactgctc gcgaggcgcc acaaacgttc
    20521 cgcggccttg gatggtgacc acccagcctt gctcgcgcag gagttccatg gcgcggcgga
    20581 ctgagccgcg ggcaatgccg tgctcctgct ggagcgagct ctcggagggc acgagctgtc
    20641 gctcctccag gtcgcctgcc ttgattctgt cccggatgat gcgggccagc tgctcgtaga
    20701 tcggcgtggg gtcgagctgg tcaaccgtca tggctagcac gttaaggacg tacttccagg
    20761 tacttacgtt gggtacgggt aggacgtgct agacgggcta tacgagttat acgtatgctc
    20821 gttcgtgcag gcgaagagag ggtgcgctgg gcggtgcagc gccgagcgtt ccgtggtcgg
    20881 acgccgggag gtccaatcca tgggtgaagg aatcacagcg gccgaggtgc aggcggtgtt
    20941 gcggcggcac ggttaccggc tccacgcggt cgaacacgtt cgcaggctgt tgttggcgcg
    21001 tgtcgacgtc gcgccgcgtg aggtcgttca gggccctcgc cggggaagtg cgcggtgact
    21061 ttctc
//
