LOCUS       NZ_CP023711            24071 bp    DNA     circular CON 06-APR-2024
DEFINITION  Paenibacillus polymyxa strain C12 chromosome, complete genome.
ACCESSION   NZ_CP023711
VERSION     NZ_CP023711.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5793823)
  AUTHORS   Sun,D., Qiu,J. and Shen,M.
  TITLE     De Novo Assembly of the Paenibacillus polymexa Strain C12 Genome
            Using PacBio Single-Molecule Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5793823)
  AUTHORS   Sun,D., Qiu,J. and Shen,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2017) College of Biotechnology and Bioengineering,
            Zhejiang University of Technology, Chaowang Road, Hangzhou 310000,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 105.2x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022649565.1-RS_2024_04_06
            Annotation Date                   :: 04/06/2024 06:53:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,129
            CDSs (total)                      :: 4,973
            Genes (coding)                    :: 4,899
            CDSs (with protein)               :: 4,899
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 42 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 13 of 74
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:37:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4794167
            Orig. end                         :: 4818238
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023711.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24071
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="17"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24071
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24071
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14071](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14071
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            242..1162
                     /locus_tag="CPY53_RS20680"
                     /old_locus_tag="CPY53_20700"
     CDS             242..1162
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="CPY53_RS20680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20700"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_031463077.1"
                     /transl_table=11
                     /translation="MQQATGQVPVIRMEGVSKIISSKAIVDNLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSINTDFEKAVSHVGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVTQERIDEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLTRTEGITVFVSSHLLSEMELMCDRVAIIQSGRLVDIKQ
                     LKNTEGEVQTAEIAFEVNDAEQAYTLAGAGRVEGNQLLLHLEREQIAEMNSLLAANGVK
                     VYAIRPVARTLEDQFLEVTGGGSIG"
     gene            1155..1937
                     /locus_tag="CPY53_RS20685"
                     /old_locus_tag="CPY53_20705"
     CDS             1155..1937
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="CPY53_RS20685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20705"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_016821229.1"
                     /transl_table=11
                     /translation="MADFFKLVHNENLKIYLRVRTWIMLGLLAVITAVIPMLISLVSDQ
                     VSVWDGIALTTLFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYIS
                     VILFSLLGTIVLVLMVTLSSWLMLSKDAPAGSVPLFSDPISYVTLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTVYNSIGLFSTDRFEWTKYVLFTHMDLKKYLDM
                     PPGTVSSNLTFSLAVLAAYYVVFIAIAWVVFVKRDVST"
     misc_feature    2111..2127
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            2198..3283
                     /locus_tag="CPY53_RS20690"
                     /old_locus_tag="CPY53_20710"
     CDS             2198..3283
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="CPY53_RS20690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20710"
                     /product="AI-2E family transporter"
                     /protein_id="WP_025364270.1"
                     /transl_table=11
                     /translation="MLQNNRFFRLTSGIVMLLLIIYLGTKVSFIFSPLVSLVSLLVVPL
                     MLSFFLYYLLRPIVDVMERRKIKRSISILLIYLVIGVLLFLFSWGVWPTLRDQVTNLFE
                     NAPKLIKSLVDQLSQWRHNQSLRQVLPPGEDPLSQLSDTLNEAFSTLSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGSKFGPKMLNFFPKKYHKDALEVMEDIDSALSSFIVSRVL
                     INVALGLMMFLGFLIIGLPYALLLAVISIFLNFIPYVGAVAASIPVVIIGFLESPSMAL
                     WSLVVVIVAQQIQDNWLSPIVFGKQLDIHPLTVVILLLVGGDLLGILGIILVIPLYMCG
                     KIVIRKVYHLFLERRVEDIME"
     gene            complement(3323..3787)
                     /locus_tag="CPY53_RS20695"
                     /old_locus_tag="CPY53_20715"
     CDS             complement(3323..3787)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="CPY53_RS20695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20715"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_045244076.1"
                     /transl_table=11
                     /translation="MFKESKKKLSTPATTDTLLANGTSFEGTIEAEANIRIDGHFQGDI
                     YSTRTVVIGESAVVRSDIIARDVILAGKVFGSITTEGRLTITSTGELYGNTATPTLVIS
                     EGGVLNGTSQMNQTMDAESPAAIDKSEDENQSSFSQDIEDSQASLQPEAG"
     gene            complement(3833..4864)
                     /locus_tag="CPY53_RS20700"
                     /old_locus_tag="CPY53_20720"
     CDS             complement(3833..4864)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="CPY53_RS20700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20720"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_017426474.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQCSAAAVILVPTLVIASIST
                     LVIGLQIRSSHIISQMETNLAVQSLQMEVTVADKDAAIGRLRQEVMELTNQATSIRERL
                     QRVTELEQQMQQFIRKHGNSSSASSNKSTITPLSWDASGHTGGELIAVHENTALLARQA
                     MDDFQEIEALLDTVERTVPRSIQQANAVQQNLERQQAAQLLQTRRLALAEQGRPSIWPV
                     GSRRMTSSFGYRSDPFTGKSAFHSGVDIAGQSGDPVYAAGAGTVLEAASSGARGKCIII
                     QHPDGLQSWYMHLSGMQVAPGDRVHKGQTIGLLGSTGRSTGPHLHFQIVKHNQPVDPLL
                     YVQ"
     gene            4987..6417
                     /gene="cls"
                     /locus_tag="CPY53_RS20705"
                     /old_locus_tag="CPY53_20725"
     CDS             4987..6417
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="CPY53_RS20705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20725"
                     /product="cardiolipin synthase"
                     /protein_id="WP_242210621.1"
                     /transl_table=11
                     /translation="MLWLLLVLIIFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYQKRKVVRKAGSQLFREFREHLWAQTKVIENVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTNGEETFDAMLKAMEQAQHHIHVEFYIFRADEIGKKFQEVMIR
                     KAREGVKVRFIVDGVGSYHLPYSFIRTCNEAGVEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGTIGFVGGINVGDDYLGKYPKVGFWRDTHLQIEGDGVYFLQNVFLSDWKLASGERL
                     MDVNLFPPHTCTGDEEVQILSSGPDQVWDTIQELCFGALTVAKKRIWITTPYFIPDPGI
                     YEALKLAAVSGIDVKIIIPYQSDSKLVHLASLSYVQELLEAGVEFYQYRKGFIHAKVVI
                     VDDLLGSVGTANMDMRSFFYNFELTAVLFATSALERLSADFVEDISNSSKIDLNVFRKR
                     PRSQKIAEILTRMLSPLL"
     misc_feature    5007..5020
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.61"
                     /tool="antismash"
     gene            6612..7556
                     /locus_tag="CPY53_RS20710"
                     /old_locus_tag="CPY53_20730"
     CDS             6612..7556
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="CPY53_RS20710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20730"
                     /product="YitT family protein"
                     /protein_id="WP_013369852.1"
                     /transl_table=11
                     /translation="MSVVSKEVQNLSEITDVTGELTKISKIPANPKNKVKRLLQRAAMI
                     VVGAALMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLLIGYKQI
                     GKTFALSTLFGIVVMSIGTALLHNVSALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISDKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKSIVEDWDPHAFIAIGNIHDVKGGRFKKKGIH"
     gene            complement(7625..8527)
                     /gene="ligD"
                     /locus_tag="CPY53_RS20715"
                     /old_locus_tag="CPY53_20735"
     CDS             complement(7625..8527)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="CPY53_RS20715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20735"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_044785763.1"
                     /transl_table=11
                     /translation="MGRAVKGTITIEGHEIAITNPDKPLWPEAGVTKALYLRKLAVLAP
                     YLLKYCHQRLLTVIRWPHGIHGDFFYQKNAPHPRPDYIETALHDGIEYIVLGKLPQLLW
                     LGNQAALEFHPSLHRTGSQLPCEWMIDLDPSREVEPRIMEAASIVGEVLASLGLDSVPK
                     TSGATGVQIIVPIRTGITFDELRSIGLLVGQFVTEKHPHLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWEEVRQDVSPLDYHLLNIEERLNQVGDLIDKV
                     PPQPVEDLLKHMRSKTHST"
     misc_feature    complement(8676..8689)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.22"
                     /tool="antismash"
     gene            8740..10026
                     /locus_tag="CPY53_RS20720"
                     /old_locus_tag="CPY53_20740"
     CDS             8740..10026
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426477.1"
                     /locus_tag="CPY53_RS20720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20740"
                     /product="sulfotransferase"
                     /protein_id="WP_339328802.1"
                     /transl_table=11
                     /translation="MIEKQGGKLVFLLSVPRSGSSLLTAILQNHSRLFATQEMWFLLSL
                     YDLPQSHARPYGGTGILRQFFKGMVPSDVLEQAARSYALEIYNGLLQGTTADMLIDKSP
                     RYYTVLEFVDRLFPAARRVWLIRNPLSIVASFKKVNQLRNGNFHLLKELGSPHFNMKMT
                     DITVGLFRYAHYFATPHPLAYPLMYEQLVANPRMEIEKLCHFLEIHYEPGMERYGNFAD
                     TPQSNLFYSMGAGDPFVMEHEQAHQNSVHSWQHLLSTMEIELYCRSIGARLFRQLGYGE
                     ALEQAEQMTGVRFEDDPDVELLSRRTHQFLQQSGFEWKTAYRMLEEQDADNKEFMTNAT
                     CHAAPHNPARMDMAQIVSDRRIQSLENRLAHSFEERNRLIAKLQSYQRPSQGFRSHLLA
                     RKFGRWASEVLSSIGKEKGGERECNCRNL"
     gene            10001..11926
                     /locus_tag="CPY53_RS20725"
                     /old_locus_tag="CPY53_20745"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="CPY53_RS20725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20745"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_153794569.1"
                     /sec_met_domain="GATase_7 (E-value: 3e-20, bitscore: 70.6,
                     seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 1.8e-24, bitscore:
                     85.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYRFGHESVYAEEGEKMMQTLQKYPADRVCAWCEGSIFL
                     GCHAQHVTPESVHERLPFYDELRDLAITADAIIDNRSELFERLAIEQGQRQGITDSELI
                     LLAYDKWGVNAASYLIGDFAFVIWDAKKHRLYGARDMTGNRTLYTHQHDGGFAFSTVVA
                     PLLVLSSLRKELHEPWLAEFLSIRAMQESVDIGTTAYKHINQLPPAHWFTMEEGKQSLC
                     KYACLDEVEPLRLKTGGEYIEAFREVFSQAVTARLRTHRAVGAALSGGLDSGAVASFAA
                     PALHLQHKPLHAYSYVPVQDFTDWTPPTLLANERSYIQSTARYVGNIRENYMDFEGKSP
                     FSEIDIWLELMEAPYKYFENSFWIRGFYEKAQEHNVGVLLTGARGNFTVSWGPALDYYA
                     RQFRRLHWLQSWQGVRQYSKLTGSRMSHLLPVMLKKATSLDARTWWGRGKQSPIPSLIH
                     PEFAKRMNVEDIPVLSGTGWRKNADQTRKEKFSNLAIANKNGVMATKLSLRYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRKAMRGHLPDDVRLNQRVRGVQPADWLHRML
                     PCWDTFMGELQVMCHDLRAAEYLNMDYIKTAMAKYRHPRPDQASDPNIRLFMHSLIVYR
                     FLCGLN"
     gene            11980..12108
                     /locus_tag="CPY53_RS20730"
     CDS             11980..12108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="CPY53_RS20730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_013369856.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEVLDINQTMAGKGWKQIDWVSDHDADLYNPS"
     gene            12237..13295
                     /locus_tag="CPY53_RS20735"
                     /old_locus_tag="CPY53_20750"
     CDS             12237..13295
                     /EC_number="2.7.1.24"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821222.1"
                     /locus_tag="CPY53_RS20735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20750"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_242210624.1"
                     /transl_table=11
                     /translation="MSPIAHDRSAHNSWVKYTAFGLRIASELTLPELIPAEPGLVEDVV
                     IRQVDLSAWRDQLEQANFVMQGERFMFLIPDTAIYAIRGGKEIEVSMLPIADPDTVRLF
                     VLGTCMGVLLLQKRVLPIHGSAVVIGGRAYAFVGESGTGKSTLAAAFRQAGYQMISDDV
                     IAINVTASAAIVYPAYPQQKLGLESLLQLEALRENKKHVRQRKHVLSLTDGNPVRAQYQ
                     DLRRIAGELNKYAVPAVDEFYNDPLPLGGVFELVSDSPNRESMREGEPVVVTEQPLNKL
                     ECLHTLLQHTYRRAIIPRMGLGEWYFDTAARMARKVEGWRLLRDSSFFTASEVVQRVLE
                     LIHKEEKSYGSH"
     gene            13282..13584
                     /locus_tag="CPY53_RS20740"
                     /old_locus_tag="CPY53_20755"
     CDS             13282..13584
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369858.1"
                     /locus_tag="CPY53_RS20740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20755"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_016821221.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.3e-24,
                     bitscore: 83.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.8e-16, bitscore: 58.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAINPAKDHYRITYGEEVYVSDMDGEKVMMSIHTGKYYNLGFTG
                     GRIWELAESSPSLGDIVTVLTNEYEVDEEQCRQQVHTFVAELEREGLLRLLRELD"
     aSDomain        13330..13563
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CPY53_RS20740_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.30E-26"
                     /identifier="RREFam002.1"
                     /label="CPY53_RS20740"
                     /locus_tag="CPY53_RS20740"
                     /protein_end="94"
                     /protein_start="16"
                     /score="83.5"
                     /tool="antismash"
                     /translation="EEVYVSDMDGEKVMMSIHTGKYYNLGFTGGRIWELAESSPSLGDI
                     VTVLTNEYEVDEEQCRQQVHTFVAELEREGLLR"
     gene            13586..14071
                     /locus_tag="CPY53_RS20745"
                     /old_locus_tag="CPY53_20760"
     CDS             13586..14071
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="CPY53_RS20745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20760"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_242210626.1"
                     /sec_met_domain="PF13471 (E-value: 8.4e-24, bitscore: 82.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQRLLLLSPEVRILLPEAWLELGCARFRQRRSFGDYSGAWGIC
                     MEETSWQCEIGQEKSIRHISQAVDVASRYTPWRSSCLVQAAAAMTLLVRRKLDCTLYLG
                     TAKNAAGQLAAHAWVRSGPIYVTGEREMGAFTVVGIFGRRAGTATNTRTADKGSSLF"
     gene            14129..15655
                     /locus_tag="CPY53_RS20750"
                     /old_locus_tag="CPY53_20765"
     CDS             14129..15655
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426482.1"
                     /locus_tag="CPY53_RS20750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20765"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_242210628.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 6.9e-84, bitscore:
                     279.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKSILELANWNEDQELTLLLSLLRKDVNLWQNTMTASQLQEID
                     WSRLLRLTEHHRVIPTVYLQLKTLNHPFIPAELLRNLQAQYHRNTLRMLHLQAEAERLT
                     RLLTAHGIRVLMLKGPALAQQLYGDVSLRTSKDIDLLIAPDDMDEAEHWMKEAGYASKS
                     GEVRVLGSWKWKDHHASFLHPQKRVEVELHWRLHPDGGREPSFDELWDCRQMGKAPAVR
                     ASQMAPATSADNRNVMTSCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAVRAVD
                     WGALLPQMRRYGGLPAGGQAWALAAALFGTPIPAPMRPISATRQAHRLALSALAFMQAS
                     VPAPYPVANGAGTGRLVRPELLPNVALTESMNTAPSDGGISANGTSGEAVLYAVSSAAG
                     ISKDASSILGDPVNTVNTAVSSLAKPVGAATVASSPAIAGATTTAFTPLPVSRAYLLSL
                     KEPRHRLWYLISRLFPSTRDSVICPLPRQLHFLYIPLRPFLWLKRRFSKH"
     gene            15676..17565
                     /locus_tag="CPY53_RS20755"
                     /old_locus_tag="CPY53_20770"
     CDS             15676..17565
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="CPY53_RS20755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20770"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_242211492.1"
                     /transl_table=11
                     /translation="MTHLRLYMTKLYSVNGGALFLNIGCMMIVSLLEGVGIYMLVPMLA
                     AIGVFGGHSEMPFLSDGFDYFLPYIPKSWLLPGMLMFFVMLLTGQAWLQRYQSILNSRI
                     QQRFMRSLRIDVYTSFMKAQWAFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVMF
                     TLIQIALAFWLSPSLTGLVFLSGLVLFVVFRRSIRNAKQLGDRTTELSQIYFAGITDHM
                     NGMKDIKSNLLEAANIHWFRSLTQRMEDNTTQFVRQNATTQFFHRIAAAVFVVSVLFVS
                     LQWLHVTPEKLIVLILIFSRLWPRFALIQASLEYIMSMISAFESVTKVQRECEAFSDPS
                     LIGLTSSENHVPFDSSVYHLSSTSTSTSTSTSTSARQPLSLRNGIECCHLDYCYEGAAE
                     PALRHINLFIPARGMTSIVGKSGAGKSTLVDVLMGFLRPTAGQIKIDGHVLDDELLPLW
                     RQSFGYVSQDPFLFHATVRENLKLADKDASEQQLWEALHFAAADSFVSRLPKGLDTVIG
                     DRGIRLSGGERQRLVLARAILHHPPVLILDEATSALDGEHEAAIQAALERMKGQMTLIV
                     IAHRLSTIRHADQIVVLDQGEVIQQGNYRQLAKEERGAFSQLLSYQSSVSAAP"
     misc_feature    17601..17614
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.43"
                     /tool="antismash"
     misc_feature    17850..17863
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.39"
                     /tool="antismash"
     gene            18220..19551
                     /locus_tag="CPY53_RS20760"
                     /old_locus_tag="CPY53_20780"
     CDS             18220..19551
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728406.1"
                     /locus_tag="CPY53_RS20760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20780"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_017426485.1"
                     /transl_table=11
                     /translation="MKKKMIIALGASAIMLANFVGSTYADSKTVVPVTAPYNTNQIAEW
                     LEAHAKPLKTTNPTAPLNDLKPLKNMVGSASIVGLGEATHGAHEVYTMKHRIVNYLVSE
                     KGFTNLVLEEGWDRALELDRYVLTGKGNPSQHLSPAFKTKEMLHLLSWIRQYNANPKHK
                     SKVRVIGMDIQSVNENVYNNIVEYIKRNNSDLVPRVEKKIRGLIPVTKDMDTFDSLTQK
                     EKEKYISDAKQISALLEQNKSYLNGKSREFAWIKQNARIIEQFTTMLASPPDKPSDLFL
                     KHDIAMYENAKWTEEHLGKTIVWGHNGHVSKTNMIPFIYPKVAGQHLAEYYGERYVSIG
                     TSVYEGQYNVYNNDGEFGPYGTLKSDDPNSYNYIFGQVKKDQFFIDLRKANGVTKTWLN
                     QQHPIFAGITTEGPDIPKTVDISLGKSFDILVQIQKVSPSQLHQ"
     gene            complement(19733..20647)
                     /locus_tag="CPY53_RS20765"
                     /old_locus_tag="CPY53_20785"
     CDS             complement(19733..20647)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="CPY53_RS20765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20785"
                     /product="Ku protein"
                     /protein_id="WP_242210629.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQVSGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPIAQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEVRIAPTQPQTNVVDLMAALQASIEAVKPVVTDPGPAAKKRPARKPATLTTQQA
                     VAGDAISPAPVKKKRSPAKRKET"
     gene            20856..21095
                     /locus_tag="CPY53_RS20770"
                     /old_locus_tag="CPY53_20790"
     CDS             20856..21095
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="CPY53_RS20770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20790"
                     /product="hypothetical protein"
                     /protein_id="WP_016821216.1"
                     /transl_table=11
                     /translation="MPRKPYPQQISHRVGQSQIAFRGPAAGEQDALPPEFALSHGTPPP
                     FPVAVAHVDLEAVVSTSPSHSFPSLDVERIIDED"
     misc_feature    20863..20874
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.67"
                     /tool="antismash"
     gene            21149..21328
                     /locus_tag="CPY53_RS20775"
                     /old_locus_tag="CPY53_20795"
     CDS             21149..21328
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="CPY53_RS20775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20795"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_017426487.1"
                     /transl_table=11
                     /translation="MNVERAKAIYDSTETIAVQLDGKPIWIEHVDEANGMATIQIGSRP
                     GNTQTVRVDRLEEQ"
     gene            complement(21460..22116)
                     /locus_tag="CPY53_RS20780"
                     /old_locus_tag="CPY53_20800"
     CDS             complement(21460..22116)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="CPY53_RS20780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20800"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_242210631.1"
                     /transl_table=11
                     /translation="MNNRELIIRRIAQEFKDGEVVNLGIGLPTMAVDYIPENINIMLQA
                     ENGIVGVGPKAAPGKERLDCIDSGGNYVTTVKGACYIDSALSFSIIRGGHVDVTVLGAL
                     EVDEKGNLANWMIPGKKVPGMGGAMDLVVGAKRVIVAMEHVNKNGAPKILKQCKLPLTA
                     VNVVKTIVTEKGVIDVIPGKGLMLKKIAPGLSVEDVQMATEAELMVSPHLKTIAV"
     gene            complement(22109..22777)
                     /locus_tag="CPY53_RS20785"
                     /old_locus_tag="CPY53_20805"
     CDS             complement(22109..22777)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426488.1"
                     /locus_tag="CPY53_RS20785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20805"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_017426488.1"
                     /transl_table=11
                     /translation="MNKKVNSAEEAVKRIKDGDTVMVGGFLQGGIPEELVRALVDTNSA
                     DNLTIISNDTGTTELSIYRLVKSGRVKRIFASYIGSNPETGRLLMTKEAEVQLFPQGTL
                     AEKIRAGGAGLGGFLTPVGVGTIVEKGKQKIKIDEREYLLELPLKADVALIRAHKADEA
                     GNLVINGTSRNFNMVMATAAEYVVAQTDEYVKAGEIDPNHINVPGIFVDAIVKVGGDNE
                     "
     gene            complement(22816..23556)
                     /locus_tag="CPY53_RS20790"
                     /old_locus_tag="CPY53_20810"
     CDS             complement(22816..23556)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="CPY53_RS20790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_20810"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_031463089.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPCRFINREFFIITYESDPAAIRQ
                     AVPEPLQPDGSNTVSYEWIKMPDSSGLGSYEESGIVIPCTYNGEPCNFVAQMYLDNAPA
                     ILGGREIWGFPKKWAKPRLIVEDTETLTGTLHYNNALVAMGTTPFKYNVLDEKETAKAI
                     AKTQVNLKLIPDVDGTPKIAQLVAYNLEDITVKGAWSGPARLSLIPHVNAPVADLPVRA
                     YVGGKHFIADLTLPYGRVLYDYLQ"
     misc_feature    complement(23885..23901)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.35"
                     /tool="antismash"
ORIGIN
        1 attacggtca ctcagcacta caagacccga ttcggtactt ttgatatcgt acagccttgt
       61 tatgtgacac aggaagatga ggagtggaga gtgctttgga tatacaagga gaaggaacag
      121 acgtgataag gtgctcccaa aggtgtttct gacaggataa atatggtaca atacttccaa
      181 aaccggaaat gtacagtaaa atggatgaca gcttcactcc gggtggaagg agtttcatag
      241 catgcagcaa gcgacagggc aggttcccgt catacggatg gagggtgtga gtaaaatcat
      301 ttcctcaaaa gcgatcgtgg acaatctgac actggaggtt ccggcaggac aggtatttgg
      361 tttcctcgga ccgaacggtg caggaaaaac gaccaccatt cgtatgatgg ttggcctgat
      421 ttcgatcagc aagggtgata ttcatatatg cggagacagc atcaataccg atttcgaaaa
      481 ggctgtttcc catgtcggtg cgattgttga gaacccggag atgtacaagt ttttgacagg
      541 ctatcaaaat ttgcagcatt ttgcgcgcat gtctccaggg gtgacccaag agcgtataga
      601 tgaagcgatt cgtctggtag gactcggaaa ccgaattcac gataaagtca aaacctactc
      661 gctcgggatg cgacagcgac tcggagtagc tcaggcgatt ttgcatcgac cgaagctgct
      721 cgtgctggat gagccgacca atggcttgga cccgcagggt attcgtgaac tgcgggatta
      781 tttgcgtcaa ttgacccgta ccgaaggaat taccgtgttt gtatcaagcc atttgttgtc
      841 cgaaatggag ctgatgtgcg accgcgtggc cattattcag agcgggcgat tggttgatat
      901 taagcagttg aagaatacag agggagaagt gcagacggcg gaaattgctt ttgaagtcaa
      961 tgatgctgag caagcctata cgcttgctgg agccgggcgc gtcgaaggca atcaactact
     1021 gcttcacctg gagcgggaac agattgcaga gatgaacagt ctgctggctg caaatggagt
     1081 caaggtgtat gcgattcgcc cggttgcccg tacgttggaa gatcaatttt tggaagtgac
     1141 gggaggcggg tccattggct gatttcttca agctggtaca taatgaaaat cttaaaatct
     1201 acttgcgtgt gcgcacatgg atcatgctgg ggctgctggc ggtcatcacc gctgtgattc
     1261 cgatgctgat ttctctagtt tctgatcagg ttagtgtgtg ggatggcatc gcattgacaa
     1321 cgttgtttac atttttcctc aatacgacgt ttacggtcat tgtagctgct gattcggtgg
     1381 ctggcgaatt tacatgggga acgattaagt tgctgctcat ccgtccttgg actcgcagca
     1441 aaattttgtt gtccaagtat atatcggtga ttttgttcag cttgcttgga acaatcgttt
     1501 tggtcttgat ggttacgctg tcctcttggc tgatgttatc taaggacgca ccagcgggct
     1561 ctgttccgct gttcagtgac ccgatatctt acgtaacgtt gaactttttg tatagctata
     1621 tcgccttatt cgtgaccatg gcttttgcat ttatgttatc cgcggtgttt cgttcgagcg
     1681 ctttggcgat tggtttgtcc ttgtttatga tgttcaccaa aacggtgtat aactctattg
     1741 gcttgttcag cacagatcgt tttgaatgga ccaaatacgt actctttacg catatggatc
     1801 tgaaaaaata tctagatatg ccgccgggta cagtaagttc caatctaacc ttttcgctcg
     1861 ccgtgctggc cgcttattat gtggttttta tcgcgattgc ctgggtggtt tttgtaaaac
     1921 gcgatgtctc cacctaaaca cgtatctctt agcatgtgtg attgaataac acgaggattt
     1981 tggcaaaatg ctgagatcac aaaaaggaag tccaatgcct agccatttgg acttcctttt
     2041 ttgctatgtt ggcactgttt tattcagtat ctatgtcatt tttgctacat attctgtaag
     2101 tgtgggtata ttgtaatcta ttttcagcaa gaatcaatca atagggtcgg tttgcgttta
     2161 aagaagtaga gagaaacaga acaggggggc gtatgatatg ctgcaaaata atcgtttttt
     2221 tcgcctgact tcaggaatcg tcatgctatt gctcattatt tacttgggca ccaaagtaag
     2281 ctttatattc agtcctcttg tatccttggt cagcttgctg gttgtaccgt tgatgctatc
     2341 ttttttcctc tattatttat tgagaccgat tgtagatgtc atggaacgga gaaaaatcaa
     2401 acgatcgatt tccatattgc tgatttattt ggttattggc gtgttactgt tcctcttctc
     2461 atggggagtg tggcctacgc tccgtgatca ggtaaccaat ttatttgaga atgcgccgaa
     2521 gcttattaaa agtctggttg atcaattgag ccaatggcgg cataatcaat ccttgagaca
     2581 agtactgcct ccgggtgaag acccgctgtc acaactgtca gatacgttaa acgaagcttt
     2641 ttcaacgctg tcagattact cggtaaagct ggtatcgttc gtatcctact tttttatcgt
     2701 attggctacc tttcccatat tgctctatta catgttgaag gaagggagca agtttggtcc
     2761 caaaatgctt aacttctttc ctaaaaagta tcataaggac gcgctggaag ttatggagga
     2821 tattgatagt gcgctcagca gctttatcgt cagtcgagtg ctgatcaatg tcgcgttggg
     2881 cttgatgatg ttccttggat ttttgattat tggtttgcct tatgccttgc tgcttgccgt
     2941 tatttcgatt ttccttaatt ttattcccta tgtgggggca gtagctgctt ctatacctgt
     3001 ggttatcatt ggatttctcg aatcgccttc catggcgctc tggtcgctgg tggtggtgat
     3061 cgttgcgcag caaattcagg ataattggct gtcgccgatt gtctttggca agcagctgga
     3121 cattcatccg ttgactgtcg tcattttatt gctagttggt ggcgacctgc tcgggatctt
     3181 gggtatcatt ttggttattc cattatatat gtgcggcaaa atcgtcatac gcaaggtgta
     3241 ccatttattt ttggaacgca gagtggagga tattatggag tgattggagg atgtactgga
     3301 tatataggag tataagccgg ccctatcccg cttcaggttg tagggaggct tggctgtcct
     3361 ctatgtcttg gctgaaactg gattgatttt catcctctga tttatctata gcagctggcg
     3421 actctgcatc catagtttgg ttcatttgac ttgtgccgtt cagtacgccg ccttcagaaa
     3481 tgaccaatgt aggggtcgcc gtatttccgt acagttcgcc tgttgatgta atggtcagcc
     3541 gtccttctgt ggtgatgctg ccgaatacct tgccggcaag aatgacgtcc cgtgcaataa
     3601 tgtccgaacg tacaactgct gattctccaa tgacgacagt gcgagtgctg tagatatcgc
     3661 cctgaaaatg accgtcaatg cgaatgttgg cctctgcctc aatcgtacct tcaaagctgg
     3721 tgccgttcgc gagcagtgta tccgtcgtcg ccggggtgga gagctttttt ttggattcct
     3781 tgaacatgat cgttttcctc caatccttta ttgtcggtat tttgcaaaac ccttattgta
     3841 catacagcaa tggatcaaca ggttggttat gcttgacgat ctgaaaatga agatgaggtc
     3901 ctgtgcttct cccggtactt cccagcaggc caatggtctg tcctttgtga acacggtccc
     3961 ccggagccac ctgcataccg cttaggtgca tataccagct ttgaagtccg tctggatgct
     4021 gaatgatgat gcacttgccg cgagctccgc tggaagcggc ctccagcaca gtgcctgccc
     4081 ctgctgcata gacaggatca ccggattgac cggcaatgtc cacgcctgag tgaaaagcgg
     4141 atttccctgt aaatgggtcg ctgcgatagc cgaaactgga ggtcatgcgc cgcgaaccaa
     4201 caggccaaat ggagggcctg ccttgttcag caagtgccag tcttcgggtc tggagcagct
     4261 gcgcggcttg ttggcgctcc aggttctgct gtacggcgtt tgcctgttga atagagcgcg
     4321 gaaccgtgcg ctccactgtg tccagcagag cttcgatttc ctgaaaatca tccatggcct
     4381 ggcgggctag aagagctgta ttttcatgca ctgcgatcaa ttcgccccca gtatggccgg
     4441 aagcatccca ggagaggggg gtgatggttg atttattact gctggcgctg gaggaatttc
     4501 cgtgtttacg aatgaattgc tgcatttgct gttccagctc tgttacacgc tggagacgtt
     4561 cgcgaatact ggtggcttga ttcgtcagct ccatgacttc ctgccgcagt cgcccaatgg
     4621 ctgcgtcttt gtctgctacc gtgacctcca tctgcaaact ctggacagca agattggttt
     4681 ccatttggga aataatatgg gaagaacgga tttgcagccc gatcacgagc gtagagattg
     4741 atgcgatcac aagggtcggg acgagaatga cagcggctgc ggagcattgt agctgcttgg
     4801 gcggttgctg tgcatcccga atgacaagca gggtcatccg gcgatttagg cttccttttt
     4861 tcataatcgc tcctttccgg acatcgctcc tatagtgctt ggttactatc tattcagctt
     4921 aagaggcaaa catgtctaaa aaattggagc tttgtataaa acgtagatat ataaggaggc
     4981 ttagacatgc tgtggttgct gttggtttta attattttta tttttcagac cgggacgatt
     5041 ctgctctttg aatttcgcaa gccgtccaaa gcggtagcct ggctctttat tttgttttgc
     5101 ttcccgctta ttggttttgt ggtgtactat tttgttgctc aggattacca gaagcgtaaa
     5161 gtggttcgta aagcaggatc gcagctattt cgtgaattcc gtgaacatct gtgggcgcaa
     5221 accaaggtga ttgaaaatgt agagcaaatg cacaatcccc atttcaagca tcaggagcgt
     5281 ctgtttaacc agttgattcg tatgtcggaa aacccgttga ctggctgcaa ccgtacacgt
     5341 gtgctgacga acggggaaga gactttcgac gccatgctga aagcgatgga acaggcacaa
     5401 catcatatcc atgtggagtt ttacatattt cgggcagacg aaatcggaaa aaaatttcag
     5461 gaagtcatga tccgtaaggc acgcgaggga gttaaggtac gattcattgt ggacggcgta
     5521 gggagctacc atttacccta ttcatttatt cgcacctgta atgaggctgg ggtcgaattt
     5581 cattattttc taccgccgtt ttttgccacg ctggaccgcc ggattaacta tcgcaatcac
     5641 cggaaaatcg tggtggtgga tggcacgatc ggatttgtgg ggggaatcaa tgtaggcgac
     5701 gattatctcg gaaagtaccc caaagtggga ttttggaggg atacgcattt gcagattgaa
     5761 ggagatggcg tttattttct gcaaaatgtg tttcttagcg attggaagct ggcttcggga
     5821 gagaggctaa tggacgtgaa tttatttcct ccacatacct gcacagggga cgaggaagta
     5881 cagattttga gcagtgggcc cgatcaggta tgggatacga ttcaggaatt gtgctttgga
     5941 gcgcttacgg ttgccaaaaa gcggatttgg ataacgacgc cgtattttat tcccgatccg
     6001 gggatttatg aggcactgaa gctggcggcc gtcagcggca tagatgtgaa aattattatt
     6061 ccctaccaat cagattcgaa actggtccac ctggcgtcac tgtcctatgt gcaagaactg
     6121 ctggaggcag gagtggagtt ctaccaatat cgaaaaggat ttattcacgc taaagtggtg
     6181 attgtggatg atttgctcgg ctcggttggg accgccaata tggacatgcg tagctttttc
     6241 tataattttg agttgaccgc tgtacttttt gcaacttcgg cgttggaacg gctttcggca
     6301 gattttgtag aggacatttc caactcttcc aaaatagatt tgaacgtgtt ccgcaaacgc
     6361 cctcgatctc aaaaaatagc tgaaattcta actcgcatgc tctctcccct cctttagagg
     6421 cggttttcgc cgtttttatc aatataatcc cgctttattg tgatttatgt gctctttgct
     6481 aacttttttg cgcaaaatca cagttttatg atatactaat cacataacta agcgccgtaa
     6541 aggagagggg actgcggaga gcagcccctt tttcggtcca atataccata ctgtaacggg
     6601 gggatttata tatgagtgta gtgagcaagg aagtccaaaa tctgtctgag atcacagatg
     6661 taaccggaga gttgaccaag atcagcaaaa ttccagctaa tccaaagaac aaagtaaaac
     6721 gcttattgca gcgtgcagcc atgatcgtgg ttggtgcagc gctgatggcc gtgggattgg
     6781 aaatattcct ggttcctaac ggcgttattg acggcggcgt tacaggtatt tccattatgg
     6841 cctccaagat tactggttat ccgctcggta ttttcctgac cctgttgaac cttccatttt
     6901 tacttatcgg ctacaaacaa atcggtaaaa ccttcgcttt atccacatta ttcggcatcg
     6961 tcgttatgtc catcggaact gcgttacttc acaatgtaag tgcattgaca cctggggaac
     7021 cgctgcttgg cgctatcttc gggggtgtca ttctcggcgt gggagtgggt cttgtgattc
     7081 ggtccggcgg ctcgctggat gggacagaga tcgtggctat tctcgtcagc gaaaaaactc
     7141 ctttttcggt cggtgagatc gtattgttcg ttaatatttt cattctggga agtgcgggtt
     7201 ttgtattcgg ttggccgaat gccctgtatt ccatgattgc ttattatatt gctatgaaaa
     7261 tgattgatat tacaattgag ggtctggatc agtccaaatc ggtctggatt attagtgata
     7321 aataccgtga tatcggagat gccctgacgg atcgtcttgg acggggtgta acttacctgg
     7381 aaggtgaagg cggctttaca ggcgagagca aaaaagtgat tttcgtcgtc attacgcgac
     7441 tggaggaagc gaagctcaaa agcatcgttg aggattggga cccgcacgcc ttcattgcaa
     7501 ttggtaatat tcacgatgtg aagggcggac gttttaagaa aaaaggaata cactagcgca
     7561 aggggacaat ttctcagcct atggctgcgg ggttcgtccc cttttttgtg cttcaaagca
     7621 tggatcaggt tgagtgtgtt ttggagcgca tatgtttgag gaggtcctct acgggctggg
     7681 gaggcacctt gtcgatcaag tcgcctacct ggtttaaccg ttcctcaata tttagcaaat
     7741 ggtaatcaag tggtgacaca tcttgccgta cctcttccca ggttagcgga gtcgagaccg
     7801 tagcaccggg acgtgcccga ggagtataag gagcggctag ggtttttccc tgataatgct
     7861 gcaagtaatc aaaatagatg gctgttccac gatccttctt taaccgttcc agtgtgaaca
     7921 gatgcgggtg cttttccgtc acaaattgtc caaccaacag tccgatgctg cgtagctcgt
     7981 caaaggtgat gcctgtacgg atcgggacga taatttgtac acctgtggcc ccggaggttt
     8041 tggggacaga gtccaaccca agcgaagcca atacttcgcc tacaatggag gcggcctcca
     8101 taatacgtgg ctcgacttct ctggatggat ccagatcaat catccattca cagggcagtt
     8161 ggcttcctgt tctgtgcaga gagggatgaa attccaacgc agcttgatta ccgagccaga
     8221 gtagttgggg cagcttgcca agcacgatat actcaatgcc atcatgcaga gcggtttcaa
     8281 tatagtctgg ccgaggatgt ggggcatttt tctgataaaa aaaatctcca tggataccat
     8341 gtggccaacg gatgacagtc aatagacgct gatgacaata tttgagcagg tagggggcta
     8401 ataccgcaag cttgcgaaga tatagcgcct tagttacacc tgcttcgggc cacagcggtt
     8461 tatccgggtt tgtgattgca atttcatgac cttcaatcgt aatcgtacct ttaacagctc
     8521 gtcccatagt gctatgctcc tttggttaac atgcagcaag atcattattt acagacaact
     8581 ggcagcattt ctacatctac ataaggttta acatgagcgt gcagcacaga atttatccat
     8641 caaagggatt gacaagatac attatgtatc ataaattata ataaaaatac gatatgtatc
     8701 tattaaaacg tcttgagcag aggtagagga ggagtgtgct tgattgaaaa gcagggcgga
     8761 aagctagtat ttctgttgag tgtccctcga agtggaagct cgctactaac tgccattttg
     8821 caaaaccatt cccgtctgtt tgccacgcag gaaatgtggt ttctgctcag tttatatgat
     8881 cttcctcagt cacatgcacg gccatatgga ggaacaggaa tactccggca attttttaaa
     8941 ggtatggtcc cttcagatgt attggagcag gccgctcgtt cgtatgcact tgaaatatat
     9001 aatggcctgc ttcaagggac gaccgctgat atgcttatcg acaaatcacc gcgttactat
     9061 acagtgcttg aatttgtaga ccgtttgttc ccggctgccc gtcgagtgtg gcttatccgc
     9121 aatcctttgt ccatcgtggc ctcgtttaaa aaggtcaatc agctccgaaa tgggaacttt
     9181 cacctgctga aggaactggg aagtccgcat tttaatatga aaatgacaga tattacggtt
     9241 ggtttgttcc ggtatgctca ttattttgcc acacctcatc cacttgcata cccgctgatg
     9301 tatgaacagc tcgtagccaa tccaaggatg gagattgaga agctgtgtca ttttctggag
     9361 atccattatg agccggggat ggaaaggtac gggaacttcg cggatacgcc tcaatccaat
     9421 cttttttata gcatgggagc gggtgatccg tttgtcatgg agcatgaaca ggcgcatcag
     9481 aattcggtac atagttggca acatctgttg agtacaatgg aaattgaact gtattgcaga
     9541 agtattggag ctcgcttgtt taggcagctt ggttacggag aagcgctgga acaggctgag
     9601 cagatgactg gagtccgctt tgaggatgac ccggatgtag agctgttgag tcggcgtaca
     9661 caccagttcc tccaacaaag tggctttgaa tggaagacag cttatcggat gctggaagaa
     9721 caggatgcag ataacaaaga attcatgaca aatgcaacct gtcatgctgc acctcacaac
     9781 ccggcaagga tggatatggc acagatcgtg agtgatcgac gaattcaatc actggaaaac
     9841 agactggcac atagctttga ggaacggaac cggctgatcg cgaagctcca aagctatcag
     9901 cgcccaagcc aaggattccg gtcccattta ttggcccgta agttcgggcg ctgggcgtct
     9961 gaagtattat caagtatcgg aaaagaaaag gggggagaac gtgagtgcaa ttgccggaat
    10021 ctatagattt gggcatgagt ctgtatatgc tgaagaaggc gaaaaaatga tgcaaactct
    10081 gcaaaaatat cccgctgacc gcgtgtgcgc ttggtgtgaa ggttccattt ttttgggatg
    10141 tcatgcccag catgtgaccc ccgaatctgt gcatgagcgt cttccctttt atgatgagct
    10201 aagagattta gccataacgg ccgatgcgat cattgacaac cgttctgagc tgtttgaacg
    10261 gctggcaatt gagcaggggc agcggcaagg tatcacggac agcgagctga ttttgctggc
    10321 atatgacaaa tggggtgtaa atgcagcaag ttatctcata ggtgattttg cctttgtcat
    10381 ttgggatgct aagaaacatc ggttatatgg tgctagagat atgacaggca atcgtacgct
    10441 gtatacccac caacatgacg gaggatttgc gtttagcacg gtagttgccc cgctattggt
    10501 tctgtcctct ctgcgaaaag aactgcatga accatggctg gccgaattct tatctatccg
    10561 tgcaatgcag gaatccgtcg atatcgggac aaccgcctac aagcatatca accagctacc
    10621 tcctgcacat tggttcacta tggaagaggg taagcaatcg ctctgtaaat atgcatgtct
    10681 ggatgaggta gagccgttgc ggctcaaaac aggcggcgaa tacatagaag ctttccgcga
    10741 ggtattctcc caggcggtaa ctgcccgatt acggacgcat cgcgctgtag gggctgccct
    10801 gagtggggga ttggattctg gagcggttgc cagctttgcc gcaccagcgc tgcacttaca
    10861 acacaagccg ctacatgcct acagctatgt acctgttcaa gattttacag attggacacc
    10921 gcctacattg ctggcgaacg aacgcagcta tattcagtcc acggctcgct atgtgggcaa
    10981 cattcgtgaa aattatatgg attttgaggg gaaaagtccg ttttctgaaa ttgatatttg
    11041 gctggagttg atggaggctc cctacaaata ttttgaaaac tccttctgga ttagaggttt
    11101 ttatgagaaa gcacaggaac ataatgtcgg agttctgttg actggggcac ggggcaattt
    11161 taccgtatcg tgggggcctg cactggacta ttatgcccgt cagtttcgcc gtttgcattg
    11221 gctgcaatct tggcagggag tgaggcagta tagcaagctt acaggcagtc gtatgtctca
    11281 tttactgccc gtgatgttga aaaaagccac ctcacttgac gctcgcacat ggtggggacg
    11341 tggcaagcaa agtccgattc cttcactgat tcacccggag tttgccaagc ggatgaatgt
    11401 agaagatatt cccgtattga gtggaactgg ctggagaaaa aatgccgatc agacaagaaa
    11461 agagaagttt tcaaatttgg cgattgccaa caaaaatggt gtcatggcga ccaaactttc
    11521 acttcgttat ggcctgtggg aacgtgatcc aaccggagac agccgtgtca ttcgcttttg
    11581 cttatcggta ccttttgaac aatatgtaca aaatggccgg gaccgtgccc tcattcgtaa
    11641 agctatgcgt ggtcatctcc ctgatgatgt tcggttgaac cagcgagtac gcggcgtaca
    11701 gcctgcggat tggctacatc gtatgcttcc ttgctgggac acgtttatgg gagagctgca
    11761 agtgatgtgt catgatttac gagctgccga atatctcaat atggactaca ttaagacggc
    11821 tatggcgaaa taccgacatc cccgtccgga ccaggcatcc gatccgaata tacgactatt
    11881 catgcacagc ctgatcgtgt accgttttct ctgtggtttg aactgatttg gatctaaccg
    11941 atcagacggc gtgccattcg tgggagggga ggtgatgaga tgagtaaaaa agaatggcag
    12001 gaaccgacga ttgaggtgct ggatattaac cagactatgg cgggtaaagg ctggaaacag
    12061 attgattggg tgtcagacca tgatgccgat ctgtataatc cgagctaacg gaagataatt
    12121 atacatgagc cgatgttggg ctgagatcca gatagcttac tgatcacgag ccgtctttat
    12181 ttcattcggg ttaggttgga ccggaagaaa taaagacgga attttaagaa cagggagtga
    12241 gtcctatcgc gcatgacagg agtgcccata acagttgggt gaaatataca gcctttggac
    12301 tcaggattgc cagtgagctg actctgcctg agctgatccc agcagaaccg ggattggtag
    12361 aggatgtggt catccggcag gttgatttgt cagcatggag ggaccaactg gagcaggcca
    12421 attttgtaat gcagggtgaa cgctttatgt tcctaatacc ggacacggcc atttatgcca
    12481 tcaggggagg caaggaaatc gaggtaagta tgttgccaat tgctgatcct gacaccgtgc
    12541 ggttgtttgt actgggcaca tgcatgggtg ttctactgtt gcaaaaacgg gttttaccta
    12601 ttcacggaag tgcggtcgtc atcggaggtc gggcctacgc atttgtaggt gaatccggca
    12661 cgggaaaatc gacgctggct gccgccttta gacaggctgg ctatcagatg atcagtgatg
    12721 atgtgattgc tataaacgtg acagcttccg cagccatcgt atatccggca tatccgcagc
    12781 agaagctggg actggaaagc ttgcttcaat tggaggcatt acgggagaac aagaagcatg
    12841 tacggcaaag aaagcatgtt ctttccctaa ctgacggtaa tcctgtaagg gcacaatacc
    12901 aagatttgcg taggattgca ggtgagctca ataaatatgc cgtgcctgct gtggacgaat
    12961 tttataacga tccgcttccc ctgggcggtg tattcgagct tgtgagcgat tctcccaacc
    13021 gtgagtcgat gcgtgaaggg gagccagtgg tggttacgga acagcccttg aacaaactgg
    13081 agtgcttgca tacattacta cagcatacat atcgtagggc gatcattccg cgaatgggtt
    13141 tgggtgaatg gtattttgat acagcggccc ggatggctcg gaaagtggaa ggctggcggc
    13201 tgctgaggga tagctccttc tttacggcgt ccgaggttgt acaacgcgta cttgaactca
    13261 ttcataagga ggaaaagagt tatggcagcc attaatccag ctaaggatca ttatcgcatc
    13321 acgtatggtg aagaagtcta tgtaagtgat atggacggag aaaaagtgat gatgagtatt
    13381 catactggaa agtattataa tttaggcttc acaggaggac ggatctggga actggctgaa
    13441 tccagtcctt cacttggaga tattgtaact gtcctgacga atgaatatga agtggacgag
    13501 gaacagtgca gacagcaggt acataccttt gtagctgaat tggagcggga aggattgctg
    13561 aggctcctac gggagttgga ctaacgtgcg gatacaacgg cttcttctct tgtctccgga
    13621 ggtcaggata ttgttgccgg aagcctggct ggagctggga tgcgcgagat ttcgccagcg
    13681 tcgttctttt ggagattact caggggcttg ggggatatgt atggaagaaa cttcttggca
    13741 gtgcgagatc gggcaggaga agtctatccg tcacatttca caagctgtgg atgtagccag
    13801 ccgttatact ccttggcgca gtagctgtct tgtacaagcc gctgccgcta tgacgttgct
    13861 ggtacgcaga aaactggact gtacactgta tctgggcaca gccaaaaatg ctgcgggaca
    13921 attggcagca catgcatggg tacggagtgg gccgatctat gttacgggag aacgagagat
    13981 gggagcgttt accgtggtgg gaatattcgg gagacgtgct gggacagcta caaatacgag
    14041 gacagcggat aaaggcagtt ctctgtttta gttttagtgc ggtataaaag gaacaaagaa
    14101 cgttcaaaga atcgaaggag aagaatccat gaccaccaag tctattttgg aacttgcgaa
    14161 ttggaatgag gatcaagaat taacgttgtt actctctcta cttcgtaaag acgtcaatct
    14221 atggcagaat acgatgactg cttcccagtt gcaggagatc gattggtccc gcttgctgcg
    14281 tctgacagaa caccatcgtg tgatacctac ggtgtatctc cagctgaaaa cgttgaatca
    14341 cccgttcatt cccgcagaat tgctgcgaaa ccttcaggcg caatatcatc gaaacacgct
    14401 gcgcatgctc catcttcaag cagaagccga gcgtctgacc aggctgctca cagctcatgg
    14461 aatccgtgtg ctgatgttga agggtcctgc tctggcgcag caattgtacg gggatgtttc
    14521 cctgcgtacc tctaaagaca ttgatttact tattgccccg gatgacatgg atgaagcgga
    14581 gcactggatg aaggaagctg ggtatgcgtc caaaagcgga gaagtacgcg tccttggcag
    14641 ttggaagtgg aaggatcatc atgcctcctt cttacatccg caaaagaggg tcgaagtcga
    14701 gttgcactgg cggcttcacc cggatggggg gcgggagccc tcctttgatg agctttggga
    14761 ctgccggcaa atgggtaaag ccccagcagt tcgagccagt cagatggcac cggcgacttc
    14821 tgccgacaac aggaatgtga tgacatcctg tatgtatacg cttggcagcg agcatcaatt
    14881 tctatacttg agcgcacacg gagcgcgtca cggctggttc aggctgcgct ggttagtaga
    14941 catcgacagg cttgcggtac gtgctgtcga ttggggggcg ctactgccgc aaatgcgccg
    15001 ttacgggggc ctgcctgcgg gcgggcaggc ttgggcactg gccgctgcgc tgttcggtac
    15061 gccgatccct gcgccgatgc gtccgatatc ggctacccgg caggcgcaca ggcttgcgct
    15121 gagcgcgctg gcctttatgc aggccagcgt ccctgcgccg tacccggttg ccaatggggc
    15181 gggtacaggc agactcgttc ggccagagct attgcctaac gtagctttga ccgagtcaat
    15241 gaataccgcc ccttcggatg gcggtatttc agctaacgga acctcgggcg aagctgttct
    15301 gtacgccgtc agtagtgctg ctggcatatc gaaagatgcc agcagcatcc ttggtgaccc
    15361 ggtgaataca gtgaacactg ctgtaagtag ccttgccaag cctgtaggtg ctgctacagt
    15421 cgcctccagt ccagccattg ctggagctac aacaacagcg tttactcctc tgccggttag
    15481 ccgcgcttac ttactttcct taaaggagcc aagacacaga ctatggtatc tcatcagccg
    15541 tttgtttcct tctaccaggg attcagtcat ttgcccactg cctcgccagc tgcatttttt
    15601 gtatattcct ttacgtccat ttctttggct gaaacggcga ttttcaaagc actaacccga
    15661 taaggagtgt acatgatgac tcacctgcga ttatatatga ccaagctgta tagcgtgaac
    15721 ggcggggcgt tatttcttaa tattggatgt atgatgatcg tcagcctact ggagggtgtc
    15781 ggcatttata tgcttgttcc tatgctggcg gccatcggcg tatttggcgg tcattcagag
    15841 atgccatttc tgtcggatgg atttgattat tttttgccgt acattcctaa aagctggctg
    15901 ttgccgggga tgctaatgtt tttcgtcatg ctgcttaccg ggcaggcttg gcttcagcgt
    15961 taccagtcca tccttaactc acggattcag cagcgtttta tgcgttccct tcgaatagac
    16021 gtatacactt cctttatgaa ggcgcagtgg gctttttatt tgcgtcagcg taaatctgat
    16081 tttagccacg tgatgacgac cgagctggcg cgtgtcagtc agggaacgaa tttgcttctt
    16141 caactgacca cggccgtcat gtttacgcta atccagattg cgctggcttt ttggctatcc
    16201 ccttctttaa ccgggctggt gtttctgagt ggcttggtgt tgtttgtcgt gttccgtcgc
    16261 tccatccgaa atgccaaaca attaggtgac cgtaccactg agctgtcaca gatttatttt
    16321 gccggaatta cggatcatat gaacgggatg aaagatatta aaagcaatct gctggaagca
    16381 gcgaatattc attggtttcg ctccctgacg cagcggatgg aggataatac gactcagttt
    16441 gtccggcaaa atgcgaccac acagtttttt catcgcatag cggcagctgt ttttgtcgtt
    16501 agtgtcctat ttgtgtcgct ccagtggctg catgttacac ctgaaaaact gatcgtgctc
    16561 atccttatat tttcccgctt atggcccagg tttgccctta ttcaagcgag cctggaatat
    16621 attatgtcta tgatctctgc ttttgagagt gtaaccaaag tgcaacggga atgcgaggct
    16681 ttctcagatc cttctttaat tgggcttaca tcctctgaga atcatgtccc attcgattca
    16741 tccgtatatc atttgtcatc tacatctaca tctacatcta catctacatc tacatctgca
    16801 cgacaacctc tatcccttcg taatggaata gaatgctgcc atttggatta ttgctacgag
    16861 ggtgcggcag aacctgcact acgtcatatt aatttgttca tacccgcccg gggaatgacc
    16921 tccattgtag gcaaatcagg agcaggcaaa agcaccttgg ttgatgtact catgggtttt
    16981 ttacgcccaa cggcggggca gattaagatc gacgggcacg tgctggatga cgaattgctg
    17041 ccactatggc gccagtcgtt tggctatgtg tcacaggacc cgtttttgtt tcatgcgacc
    17101 gtccgtgaaa atttgaagct ggccgataag gatgctagtg aacagcagct atgggaggcg
    17161 ttacattttg cagccgcgga cagctttgta tccagactgc caaaagggct ggacacagtc
    17221 attggagatc gcgggattcg tttgtcgggg ggagagcgtc aacggctcgt attagcacgg
    17281 gctattttgc accatcctcc tgttcttatc ctggatgaag cgacaagtgc gctggatgga
    17341 gagcatgaag ccgcaattca ggcggcattg gaacggatga aaggtcaaat gacattgatc
    17401 gttatcgctc accgtctgtc aacgatcaga catgcggatc aaattgttgt actggatcaa
    17461 ggtgaggtca tacagcaggg gaactaccgt caactggcaa aagaggaacg gggggcgttc
    17521 agccagctac tatcgtatca aagcagtgtc agcgccgccc cttagtcata agagagtcac
    17581 cctccataaa tatactaaaa attttgcaac aaaaaggcgc taatatttta tattctgatc
    17641 cttatgttcc agaatataaa gtaatacaaa gcttcagttt gaagagtact gaaattaatg
    17701 aggtcaaatc tttatccatt ttggcatacc aatgtctaat ccgtaagcct cacggggatc
    17761 ttttcgcaca agaaatgaag acgacttata aagaattgat aaatgatttt aaaatacgga
    17821 aaatgacaaa aagctaaata acaacccccc ttttttaaca aaaggcgtgc atcgatatta
    17881 atatcgatgc acgcctttat tgatggtact gctccatact aaccgcacag ctgtcatctc
    17941 tgtcatcaac atgtcatcat tttctttgtg acatgttggc gctgatcaat acgttagcga
    18001 gcattgcatg tcacatgaaa tagtgaagat ttgtaactag cttaaatgat agcgagtgag
    18061 tgacaattgg attactgaag acgacccaat atgcttgtat gcagaaagag tcgtacttca
    18121 aaaaaatcca tgaggtgaat gccgaatttt aaattgatgg ttaaagggga tttttaggga
    18181 atttagaaaa ataataagta agtatttcag gaggttttta tgaaaaagaa aatgattatt
    18241 gcacttggtg cttctgctat aatgctggct aattttgtag gaagtactta tgcagattcg
    18301 aaaacagtag ttcctgttac agctccctac aatacaaatc aaatagcaga atggttagaa
    18361 gcgcatgcaa agcctttaaa aacaacgaat ccaactgcac ctcttaatga tttaaaacca
    18421 cttaagaata tggtaggttc agcttcaatt gtaggtttag gtgaagctac acatggggct
    18481 catgaagttt atacaatgaa acaccgcatt gttaattatt tagtatctga aaagggcttt
    18541 accaacttag ttttagaaga gggatgggac agagctttgg aacttgatcg atatgttctt
    18601 actggtaagg gaaacccaag ccaacatcta tcacctgcat ttaagacgaa agaaatgtta
    18661 catctactta gttggattcg gcaatataat gctaatccaa aacataaatc taaagtgcgt
    18721 gtcattggga tggatattca atcagtaaac gagaatgttt ataataatat agtagaatat
    18781 ataaaaagaa acaattcaga tcttgtgcct agagtcgaaa agaagataag agggcttatt
    18841 cctgtaacaa aggatatgga tacctttgac agccttacgc aaaaggaaaa agaaaagtat
    18901 atttcagatg ctaagcaaat cagtgcttta ttagaacaaa ataaaagcta tctaaatgga
    18961 aaatccagag agttcgcatg gataaaacaa aatgcccgta ttattgaaca atttactaca
    19021 atgttagcgt caccacctga taaaccatcc gacctttttt tgaaacatga tattgcaatg
    19081 tatgaaaatg cgaagtggac tgaagaacat ttaggaaaaa ccattgtttg gggacataac
    19141 ggacacgttt cgaaaacaaa tatgattcct tttatatacc ctaaagtagc tgggcagcat
    19201 ttagcggaat attatgggga acggtatgta tctattggaa catcagttta cgaagggcaa
    19261 tataatgtct acaataatga cggtgaattt ggcccatatg gaacattaaa atcagatgat
    19321 ccaaacagct ataactacat ctttggacag gtcaaaaaag atcaattttt tatagattta
    19381 cgtaaggcga acggagtaac aaaaacttgg ttaaaccaac aacatccaat tttcgctgga
    19441 ataactacgg aaggccctga tataccaaaa actgttgata tatcattagg taaatcgttt
    19501 gatatacttg ttcaaattca aaaagtgagt ccatctcaac tacatcaata aatttgtaat
    19561 aatgtggctc aacgaagtgt agtattgatg gtagtgttaa gtgtcaatag agttgattaa
    19621 aaatgtcagt catgttattc cattaaaggg gatgtaggat agaaacactt cgccatcccc
    19681 ctaaatgaaa attttctgtc tctacattta gttatttcct ttcctgtaaa gctcacgttt
    19741 ctttacgttt agcagggctc cttttctttt tgactggagc aggagagatg gcgtcgcctg
    19801 ccacagcttg ttgtgttgtc agggttgctg gtttacgcgc aggacgtttt ttcgcagcag
    19861 gaccaggatc ggtaacgaca ggcttcactg cctcaatact ggcttggagg gcagccatta
    19921 aatcaaccac attggtctga ggctgtgttg gggcaattcg cacctcttcg ccagctactt
    19981 tatgctggat aagatccagc agacgctcgc ggtactgatc cgtatacttt gctgcatcaa
    20041 aaggggtaga tagctgctca atcaacattt ttgccatggt cagctctttc tctttaacct
    20101 cctcctgtcc aggtaagttg ggaacttgag caatgggacg gatttcgtcc gggtaaaaca
    20161 tggtctccac cgccaagcat tcatccagca cgcgaatggc tgccagactg cttttcgagc
    20221 ggatggagat ttgggcaatc ccgatttttc cggtatcctt cattgcattc atgagcagct
    20281 tatacgcatt ggagccggcc tgatccgggg acaaataata cgttttctga aagtagatcg
    20341 gatcaatttc ctgtaaatcc acaaagtcca aaatcacgat atttttatcg gcttgcccgc
    20401 taacttgctc cagttcctcc ttgtcgaaca tgacaaattt tcctttttca tattcgtatc
    20461 cttttccaat ttcctcccat tcaacctcct tatcacaaac agggcacttc cgtacatagc
    20521 tcagtggact cccacattcc ttgtgaatat aacgcatgga aatatccttg tcctcagtag
    20581 ctgaaaacat tttaactggc acatgaacca gcccaaagct gatcgcgcct ttccagactg
    20641 tatgcatacc gccagtcctc cttttttacc cgcatatttc atattttgat tccggacacc
    20701 cgggctgtga gcatttcctt tttcacttag tatgcttcgc acaaaggaat gtatgaggtg
    20761 caaatgtagg ctacgaattg cttttacttg cgcatggttt cggttttatt ggtgaatgtt
    20821 aagtcatatc cgattcaaaa ggaggtacac cattgatgcc tagaaaacct tatcctcagc
    20881 agatcagtca tcgtgtgggg caaagtcaga ttgcctttcg agggcctgct gcaggcgaac
    20941 aggatgcatt gccacccgag tttgctcttt cacatggaac gccgccgcct tttcccgtag
    21001 ctgtcgctca tgtggatttg gaggctgtag tttcaacttc gccttctcat agctttcctt
    21061 cattggatgt ggaacggatt atagacgaag actaggtgac ctatatttct aaatattgca
    21121 caaaaacaag gagcaggagg agaacagtat gaatgtggaa cgagcaaaag ccatttatga
    21181 ttcaaccgaa acgattgccg ttcaattgga tggcaaaccg atttggattg agcatgtaga
    21241 tgaagcgaat ggtatggcaa cgatacagat cggaagtaga cccggcaata cacaaaccgt
    21301 tcgtgtggat cgattggaag aacaatagga gagggaatcc aacctaaaaa ggctcgcaat
    21361 tgctcaatga gcaattagcg aaccttattt tatataataa gtgcgattgt ggagacaagt
    21421 taaacgccaa acaagttaat ttgaaggtgg aactgttttt tacactgcaa tggtcttcaa
    21481 atgtggagaa accatcaact cagcctctgt tgccatttga acatcttcca ccgacaaacc
    21541 tggagcaatt ttcttgagca tcagcccttt acctggaata acatcgatga cacccttttc
    21601 ggttacgatg gtctttacca catttacagc ggttaggggc agcttgcatt gtttcagtat
    21661 tttcggcgcc ccatttttgt tcacatgctc catagctaca atcactctct tggctccaac
    21721 caccaaatcc atggctccgc ccatgcccgg cacctttttc cctgggatca tccagtttgc
    21781 aaggttgcct ttctcatcga cctccagagc acccagaacg gtaacgtcca catgccctcc
    21841 acgtataatg gaaaatgaaa gcgcactgtc aatatagcag gctcctttca cggttgtaac
    21901 gtagtttccg cctgaatcga tacaatcaag tctttctttt cccggagctg ctttgggacc
    21961 aacgccgaca attccgttct ccgcctgcag cataatatta atattttccg ggatgtagtc
    22021 caccgccatg gtaggtaatc caataccaag attgaccact tcgccatctt tgaattcctg
    22081 ggctattctt ctaataatca attctctatt attcattgtc tccacccacc tttacaatcg
    22141 cgtcgacaaa tattccggga acattgatat gattggggtc aatttctccc gcctttacgt
    22201 attcgtctgt ctgagcaact acatactcgg ctgcggtagc catcaccata ttgaagttgc
    22261 gtgaagtgcc gttgatgaca aggttccctg cttcatcagc tttatgggct ctgatgagcg
    22321 ccacatcggc tttgagcggt agttcgagca aatattctct ttcgtcaatt ttgattttct
    22381 gttttccttt ctctacaatg gttcctacac ctacaggtgt taaaaatcca cccaaaccgg
    22441 ctccgcctgc gcgtattttt tcagcgagcg tcccttgtgg gaagagttga acctccgctt
    22501 cttttgtcat caagagcctt cctgtttcgg gattggagcc aatataggat gcaaaaatcc
    22561 gcttgactct accacttttt acaagtctat aaatagataa ttccgttgtg cctgtgtcat
    22621 tggaaataat cgtaagattg tcagcggaat ttgtatcgac aagcgcacgc accagttctt
    22681 ctggaatgcc tccttgcaga aaacctccga ccatcaccgt atctccgtct ttgattctct
    22741 taacagcttc ttcagcggag tttacttttt tattcatggt tccgtctcct tatctatttt
    22801 ttaggaaagc atactttatt ggagataatc gtagaggact cttccatatg gaagtgttag
    22861 gtcggcaata aaatgttttc cgccaacata agctctaacc ggcaaatctg ccaccggagc
    22921 gttgacatgg gggatcaggc ttaatctagc aggtcctgac caggcgcctt ttacagtaat
    22981 atcttcgaga ttatacgcca ctaactgagc aattttaggg gtgccgtcca catcagggat
    23041 taatttcaaa ttaacttgcg tttttgcaat ggctttagcc gtttcttttt catcaagaac
    23101 gttatatttg aaaggggtgg ttcccatggc taccagggcg ttattataat gcaaggtacc
    23161 cgtcagcgtc tctgtatcct caacgatcag gcgaggtttc gcccattttt tcggaaatcc
    23221 ccagatttca cgtcccccca gaatagcagg tgcgttatcc agatacattt gggcaacaaa
    23281 attacacggt tctccattat aagtacacgg aatgacaatg ccgctttcct catagcttcc
    23341 taaaccggat gaatcgggca ttttgatcca ttcataggaa accgtattac ttccatctgg
    23401 ctggagaggt tcagggaccg cctgtctaat cgcggcggga tcggattcat aggtaataat
    23461 aaagaattcc cggttgatga accggcatgg cgggcgtcca taactgccgc tggccgcagg
    23521 catggattgg agtgaaagta catctttttg attcatagcg atctcccttc ctttttaaga
    23581 ggtatttcaa caattatctt gaacaagcac tttaaatgag agcattttca accagcatgg
    23641 ctattcccat tcccgttcca atgcataacg agactacgcc ataacgtgaa gatctgcgta
    23701 ccatttcatg aaccaacgta accaataccc tagcaccgct tgcaccaaca gggtgaccaa
    23761 ttgcgatcgc gccgccattg acattgactt tctctggatt aattccaagc tctttttgca
    23821 ccgctagagc ttgtgcagcg aacgcttcgt taatttcaaa gagatcaatg tcatctatag
    23881 acattccctg tttcttcagc agtgacgaaa tggcttttac cggtcccatt cccatatatg
    23941 cagggtcaac accaacaagc gagtaacctt tgatatatgc caacggcttt aacgcatgtt
    24001 ccttacattt gtcttccgac acgactagca tagccgccgc accatcattg atgcccgaag
    24061 cgtttcccgc a
//
