LOCUS       NZ_CP023711            22388 bp    DNA     circular CON 06-APR-2024
DEFINITION  Paenibacillus polymyxa strain C12 chromosome, complete genome.
ACCESSION   NZ_CP023711
VERSION     NZ_CP023711.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5793823)
  AUTHORS   Sun,D., Qiu,J. and Shen,M.
  TITLE     De Novo Assembly of the Paenibacillus polymexa Strain C12 Genome
            Using PacBio Single-Molecule Sequencing
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5793823)
  AUTHORS   Sun,D., Qiu,J. and Shen,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2017) College of Biotechnology and Bioengineering,
            Zhejiang University of Technology, Chaowang Road, Hangzhou 310000,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 105.2x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022649565.1-RS_2024_04_06
            Annotation Date                   :: 04/06/2024 06:53:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,129
            CDSs (total)                      :: 4,973
            Genes (coding)                    :: 4,899
            CDSs (with protein)               :: 4,899
            Genes (RNA)                       :: 156
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 110
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 74
            CDSs (without protein)            :: 74
            Pseudo Genes (ambiguous residues) :: 0 of 74
            Pseudo Genes (frameshifted)       :: 26 of 74
            Pseudo Genes (incomplete)         :: 42 of 74
            Pseudo Genes (internal stop)      :: 21 of 74
            Pseudo Genes (multiple problems)  :: 13 of 74
            CRISPR Arrays                     :: 4
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:37:22
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1572925
            Orig. end                         :: 1595313
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023711.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22388
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="8"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22388
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22388
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12388](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12388)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(839..855)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 24.6"
                     /tool="antismash"
     gene            complement(1049..1498)
                     /locus_tag="CPY53_RS06675"
                     /old_locus_tag="CPY53_06705"
     CDS             complement(1049..1498)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821725.1"
                     /locus_tag="CPY53_RS06675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06705"
                     /product="hypothetical protein"
                     /protein_id="WP_016821725.1"
                     /transl_table=11
                     /translation="MDGRIITCRSIGVYDHALTRGNKYIVKNEDGDKYRIIGNHEKGVW
                     ISKAYFIEGNIEMPYLETWKFDDDPKEFDLVEVTLTFSDGSERWSLVTTPQKLVNHFKK
                     EKELPGFNIKHLIIMKTMNHDNIEKTLKYLEANDELTEASKALER"
     gene            complement(1737..2696)
                     /locus_tag="CPY53_RS06680"
                     /old_locus_tag="CPY53_06710"
     CDS             complement(1737..2696)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428277.1"
                     /locus_tag="CPY53_RS06680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06710"
                     /product="hypothetical protein"
                     /protein_id="WP_017428277.1"
                     /transl_table=11
                     /translation="MNSNIKENIKFNKMRNNNLFSGCIHQDEFCNRISRAHSIQNNGIL
                     NKLSRNSEVMAIDFSKVYLDKGNFKLFKVGRDKASTFTGFCNHHDSSIFSPIENNDYKP
                     TDSQHNFLFAYRAFALGYYERYSAYQLIKARVEDDPRNLHTELGARYRLYDDHLKVIEN
                     YKIIMNKYLDNSRFDRITTDVLIWPQEYGFASTSMFFIEKDNEGKTINKMNSYISPFFF
                     TFFPHAGKTYVLMSYFTKDKSKYRFIRDQILTLSMEEQRIAISNLIALYIENVFISPDL
                     WDNLPSSTREKYYQICNTSKGKTKPNKLVAFKNFNLFV"
     gene            complement(2856..3344)
                     /locus_tag="CPY53_RS06685"
                     /old_locus_tag="CPY53_06715"
     CDS             complement(2856..3344)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428278.1"
                     /locus_tag="CPY53_RS06685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06715"
                     /product="hypothetical protein"
                     /protein_id="WP_017428278.1"
                     /transl_table=11
                     /translation="MKNHDDEKSALEEAAVSIFVDLYNLNREDHLEVIERRERPDYILK
                     SIKDGLVGLEVTHLFYDADEAKMLFGRSAEEMHGLENSASYMQVLNELLKQKEKKIEKY
                     DAAYPIALLIRNASPIFGMSDFLRNKNAIYKPEKYTHIWFVSKDGNDNEWSLKNLLTV"
     gene            complement(3519..4157)
                     /locus_tag="CPY53_RS06690"
                     /old_locus_tag="CPY53_06720"
     CDS             complement(3519..4157)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821728.1"
                     /locus_tag="CPY53_RS06690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06720"
                     /product="hypothetical protein"
                     /protein_id="WP_016821728.1"
                     /transl_table=11
                     /translation="MTDKEIFNEVIQEGGMINPYFGQILENGIDFVPYIGKLVQTVKIN
                     RLIRRFKEHDKKINFISDLAADSVLSSEYISQRIFRIIFSDLFEEHEDAKINLILNGFE
                     NIFIEQNSNESVIINFYDMLRSLRYLDLKRLFYLAGLTEETITFVQGSDEHGLIRNIDR
                     RLENNGLLNIKKTLKDIGGSDSDKDRKDVEISLYGKKFLKFILEGDGLQ"
     gene            complement(4376..4948)
                     /locus_tag="CPY53_RS06695"
                     /old_locus_tag="CPY53_06725"
     CDS             complement(4376..4948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821729.1"
                     /locus_tag="CPY53_RS06695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06725"
                     /product="hypothetical protein"
                     /protein_id="WP_016821729.1"
                     /transl_table=11
                     /translation="MKTINISYIALVVSLAGLLVSFINVNRQRKAAYKNETEKFKRDLR
                     LKANDEFIELLFQFLENTKENRTLSIPFDDRYLNSDIKTRIREFDERFWEIAKTWVKCH
                     SALETFYLKRIVVIKQYSDMYTKIRQSGIELDQALWDLKNDYIGTGDIKLIRDKVNTYQ
                     LRAEEFISLLEESIQKLQEDFLGHLFE"
     gene            complement(5101..5712)
                     /locus_tag="CPY53_RS06700"
                     /old_locus_tag="CPY53_06730"
     CDS             complement(5101..5712)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688359.1"
                     /locus_tag="CPY53_RS06700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06730"
                     /product="hypothetical protein"
                     /protein_id="WP_100212688.1"
                     /transl_table=11
                     /translation="MNSNDFSWKEVYSYWKHFIEEYSYRSIDELSFKKIKIQPQLNPNL
                     NIGTEIIDWWPTNEVEYRTKKLNDRGILGADWDTVVGFNRTAEMLWNNKESNEQQALIW
                     IAAGLNEILSHLPEEWRGDPYRFIYETKLNIMKEFKNRDMWSWHGSTRNFLPVTVNKFM
                     ELYSKPMEIYNLMNIIAIDNVFSRNAWTLVCVSREEDDSV"
     gene            complement(5847..6074)
                     /locus_tag="CPY53_RS06705"
                     /old_locus_tag="CPY53_06735"
     CDS             complement(5847..6074)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821731.1"
                     /locus_tag="CPY53_RS06705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06735"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_016821731.1"
                     /transl_table=11
                     /translation="MKRHWLEGGIHKQVSIHSLRHSFATHVLENGIDLRYIQELLGHQS
                     VRTTERYTHVSRRDIGRIQSPLDRMSGQED"
     gene            complement(6071..6247)
                     /locus_tag="CPY53_RS06710"
     CDS             complement(6071..6247)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821732.1"
                     /locus_tag="CPY53_RS06710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_016821732.1"
                     /transl_table=11
                     /translation="MKITYFIGMKQEGSANAAFRSGFCGGREVYRGGAARRLAVSRAEG
                     RPPPDGTFSAESI"
     gene            complement(6440..6820)
                     /locus_tag="CPY53_RS06715"
                     /old_locus_tag="CPY53_06740"
     CDS             complement(6440..6820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821733.1"
                     /locus_tag="CPY53_RS06715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06740"
                     /product="immunity 22 family protein"
                     /protein_id="WP_016821733.1"
                     /transl_table=11
                     /translation="MNCFEKNMVSVWYGHFASEDELFEYVEIKYPEDENEDVFSGFLND
                     HEIDDFDEDFAEGVFLMDGADDGIKDVSYVDSFLSPLLHDLSKIDGKYNSLFFIYDCNT
                     SSLPEKNGEKLRFLVAYPYARD"
     gene            complement(6979..9042)
                     /locus_tag="CPY53_RS06720"
                     /old_locus_tag="CPY53_06745"
     CDS             complement(6979..9042)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372332.1"
                     /locus_tag="CPY53_RS06720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06745"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_016821734.1"
                     /transl_table=11
                     /translation="MSQNMKKRVFRSSSIANTLAMVLLVIIVVVFATLGTFMYASTQSM
                     LVKQQEAMLQTKTQATVSQFDALFKEKGSLVKQMSTNTLFRQYIETTESAEMVKTSPYA
                     AATQATLAAIVKEEPSFADAWIAGIHGKGFFLQNDGAASKPDFDIHSRPYFKPAVEADG
                     LYYSEPYKDVNSGNVVMGIFYPIKDSSNQLIGFAAVDIAFKDIPVVMQSYSLGNTGYSI
                     LASKTGDILYHPDQNKVLKEKINESTGDLGEIGKKMIAGESGVQLINDNGERRYIGYAT
                     SKDTGWSVGLTISEQEALSELRTFTWITIGGFAAATILLVVICYITLRYLLRAIPKLLA
                     KIKLIENGDLTVPFDTNSHNEIGQISQGVHNMVQKIQGMLQMVGGSAQVLNQSSHDLQS
                     ISSRTAITMNDTATAINEIANATNYQSIETDNILQKTGALSGQIDEIANDAKTIETMVQ
                     TSAEQSGQGLAVVDQLSKWAEENHNSTQAMSAIIQDIDLSRHEISSIVDTVNQIATQTN
                     LLALNASIEAARAGEQGKGFAVVAGEVRKLAEQTARATQEIYKKVRVIEEKTSVSVEHT
                     VHGLKIAEENARSVEDTKQVFFSINKDLEDLKLRMIQISTNTSKVHKHKDEILQALEII
                     SSTTEENSASTEEVSASTQEQLESFEQVAELSKQLNQLSTKLQDELKQFKVE"
     misc_feature    complement(9257..9270)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.15"
                     /tool="antismash"
     gene            complement(9326..9865)
                     /locus_tag="CPY53_RS06725"
                     /old_locus_tag="CPY53_06750"
     CDS             complement(9326..9865)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428282.1"
                     /locus_tag="CPY53_RS06725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06750"
                     /product="CueP family metal-binding protein"
                     /protein_id="WP_016821735.1"
                     /transl_table=11
                     /translation="MKKGILVASGLVVAALGTYLITGNFQKEGANKLGTTDIKQLVHDF
                     SAGKATGQSASINSSQLMVTGDNNQTINYDLPDNEFFVSIAPYVEETHPCATHSLTGCQ
                     GEIKNGAFNVTVHDSEGNIIMENAAMKSQPNGFIDLWLPRDKTYRISVNHEGKTAQTEF
                     STYEKNDTCITTMQLG"
     gene            complement(10001..12388)
                     /locus_tag="CPY53_RS06730"
                     /old_locus_tag="CPY53_06755"
     CDS             complement(10001..12388)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007431396.1"
                     /locus_tag="CPY53_RS06730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06755"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_242211181.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-43, bitscore:
                     147.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHHMNEKFRADTGYQLAEQKALQYFASLYNQVKDKTYVTSLTEDI
                     HIWKRNHIHSSSWLSFFSRNKRKPDTRDYYRYIQWLSYTGKLDDYLKRSVSYIYMRDLG
                     KALDSADTQTRIQRVIADVKRYLLKPTHANRRDQPEFMNLAGVYRWSQKEGIETTVIWL
                     INKLNSVSSHIPEEMDAEHAQRKLIKIIIGVILHVMEEMDEAVTPSERSRRLDEAIRLG
                     YSYGLTYPFIDDLLDSQLLTVQEKEQYSHMIRTALLNGSVPELGDWTGDHMKFIRYIHS
                     ELSDAFEYIKAHQRPDTQQTFFEQSYVFFHSQDIDRDKDLTRANYTNEELYIPVILKSA
                     SSRLIVRSVISAPEDEGFELRTFYYGIYNQLADDFADMADDMRDGAVTPYTYYLKYHHQ
                     RSDLINPFELYWAVISHLIHNVYDSDAMAREVILDRAINGLKRYKERVGVEKYNEIMGI
                     FASGNPEFNRLIQKMVGKAEDVDFLDKLLRDQMITHLKNDSREKEDFMNTVKTIRDQIN
                     NQLKITKPSGIEAMKEQLIDAANYSLEGDGKRIRPILTWVMGVNEYGLDASAIVPLLRS
                     LEYMHTASLIFDDLPSQDNASTRRGRQTLHQVHNSATAELTGLYLIQKAIGEQASLSQF
                     NAETVLALIQYSARKAEDMCMGQAMDLDSKGKALTLEQLNMMCFYKTGVAFEACLVMPA
                     MLAQTEESEIAALQKFAYHMGIAFQIKDDLLDVEGDTLLLGKPVGQDSDNNNSNFVSIL
                     GYEGASKEMWEHYCLAMEALKEVPRNIAFLKHLMNYIVNRDR"
     gene            12567..13136
                     /locus_tag="CPY53_RS06735"
                     /old_locus_tag="CPY53_06760"
     CDS             12567..13136
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1296: tellurium
                     resistance protein, TerD"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372335.1"
                     /locus_tag="CPY53_RS06735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06760"
                     /product="TerD family protein"
                     /protein_id="WP_242211182.1"
                     /transl_table=11
                     /translation="MSISLIKGQKVDLTKNNPHLSVLKVGLGWDPMRGRSMDIDASALL
                     LNENGKLTQTKNLVYFGNKNSPCGAVVHSGDNLTGHGDGDDEVITVSLQQLPPEVHRVV
                     FIVNIFRFFSFGRRKDFSMVNNAYIRVLDALQDEEILRYNLTEDYKGMCSIRVGEVYRY
                     GGEWKFGAIGEGSTITSLNELVKTYE"
     misc_feature    complement(12593..12611)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 23.85"
                     /tool="antismash"
     gene            complement(13180..14100)
                     /locus_tag="CPY53_RS06740"
                     /old_locus_tag="CPY53_06765"
     CDS             complement(13180..14100)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017814990.1"
                     /locus_tag="CPY53_RS06740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06765"
                     /product="hypothetical protein"
                     /protein_id="WP_242211183.1"
                     /transl_table=11
                     /translation="MSHLDKQLHSFVDISNNIEGFEIVSTQFGPDGRVYILLIDKVPER
                     VRGMFTPASLKEKRTYKVLILDDHIQEVCLEGQQFNYHYVQPLQDYLLLVGARCHYYGP
                     DQYDLNGKIIDYEGRTVNELLLGDGIQSVQVTKEGTIWTSYFDEGIFGNYGWNEPVGSS
                     GLVAWNKEGHKIYENQAADIHDCYALNVVSEQEIWFYYYSDFSLGRISGSDRTNITFMN
                     PRISGCSGVATDGYHFLFDGGYGKNGQYVLKKNVKPGSLSKGQHIRFLNDDQKFLQPHE
                     QDFRKDRLLLREGSLLYQLAVEEIV"
     gene            complement(14313..15254)
                     /locus_tag="CPY53_RS06745"
                     /old_locus_tag="CPY53_06770"
     CDS             complement(14313..15254)
                     /EC_number="3.2.2.-"
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372337.1"
                     /locus_tag="CPY53_RS06745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06770"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_242211184.1"
                     /transl_table=11
                     /translation="MALNKERFYGCLAGLAVGDALGTTVEFSSPGTFEPVTDIVGGGVF
                     GLKAGQWTDDTSMALCLAQSMVQKDNFDPADQMRRYTNWYHLGYMSSTGMCFDIGGATR
                     TALHRFEATGDPYSGSVDPMTAGNGSIMRLAPVAMAYANRPEEAVMYAELSSRTTHGAV
                     ESVEACAALASILVAGLRGADKESMLSPDVCYKWRRKDQSAYSAAIEEIIQGSYKHKEP
                     PEIQGSGYVIRSLEAALWAFHHSASFEEGALLAVNLGDDADTTGAVYGQIAGAYYGLSS
                     IPSHWREKLAMKETIDELTEALWQKADKGQTL"
     gene            complement(15338..16429)
                     /locus_tag="CPY53_RS06750"
                     /old_locus_tag="CPY53_06775"
     CDS             complement(15338..16429)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688153.1"
                     /locus_tag="CPY53_RS06750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06775"
                     /product="hypothetical protein"
                     /protein_id="WP_242211185.1"
                     /transl_table=11
                     /translation="MMPFHHVSLPDLPPSIGRLTAIHPVKGGSQGSITLLALNTQAELW
                     RLELRSGSAELCTRICIPDFNPLQPVQVVTSPDGKYAAISNRFGRHAAVYDLVHAQEKM
                     QLSRDEYHYDKSMFPLAFVHQDGACILVHGTEWNRLDLTDVETGLPLTARPTPVYNSES
                     KDEHYLDYFHGRLLASPEGKWIADTGWVWAPLGVVRTWSLSDWLLNPWESENGPSVRHL
                     WQTIDWDGPVCWTGPDTLAVWGQMDADLMEEEDWGEEGVEPAVVLFDMTQPGYRRVLSA
                     IPPLNCKPDEDGIYPYPQADMAVCGDRLFLWGKEVPLQVWRLSSGAREHVDTERFPLIY
                     HQEAGIFVELHPDSGCKALSYDE"
     gene            complement(16426..17421)
                     /locus_tag="CPY53_RS06755"
                     /old_locus_tag="CPY53_06780"
     CDS             complement(16426..17421)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013372339.1"
                     /locus_tag="CPY53_RS06755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06780"
                     /product="hypothetical protein"
                     /protein_id="WP_242211186.1"
                     /transl_table=11
                     /translation="MSFSEIYDYKLRAYFNERISDLNHEDLIYSYPDQEQNLRILTLNI
                     NEQDHISLVRWHDLFDRSLFTKMDHPILSVTDAERLIRLLALIFNMFDIHKDVAYCRKN
                     LCCVYYQYQVLHLAERGNEFSLTQDRLFFLHLLLFELGLGDDIYDRLTIENNKILYSME
                     DGQQYDLHILIDILHEHINKNKMDMDTRATLGKIKILQGQLVNFILGSHDVYDFPYDDF
                     NKPFVEVTMFIQAYNSNKNRVLEVLIDCINEHQSPTEQFISNMIMMNYSYFILKSNPSE
                     ITYFKCFCKKKPGVFMKVLSALLELRFFIDKSSFTNTGINYYLSRLKGVK"
     misc_feature    complement(17503..17516)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.61"
                     /tool="antismash"
     gene            17603..18253
                     /locus_tag="CPY53_RS06760"
                     /old_locus_tag="CPY53_06785"
     CDS             17603..18253
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428289.1"
                     /locus_tag="CPY53_RS06760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06785"
                     /product="hypothetical protein"
                     /protein_id="WP_242211187.1"
                     /transl_table=11
                     /translation="MKQLSEALTRFVHQQNLYNEAYGLFQDHDIQPRSESITDCWDKRV
                     PVSPELEYLYSYYEMIDAKAAGTHKLKNAAVEVGDAAVLFFVAPEHLYRQQLGYRFITS
                     DELVHESSSWPSHHVVIATFNDDPVIVDTSAPGSPVYAAIESGGAQQVADSLANFFTAL
                     SILIEGACTFKGELIDEDTYETKAAYIEHVKPLLHHLLGENQTTYLLNYLSFC"
     gene            18288..18857
                     /locus_tag="CPY53_RS06765"
                     /old_locus_tag="CPY53_06790"
     CDS             18288..18857
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017428290.1"
                     /locus_tag="CPY53_RS06765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06790"
                     /product="DUF1697 domain-containing protein"
                     /protein_id="WP_242211188.1"
                     /transl_table=11
                     /translation="MIYIALLRGINVGGNNKIEMKKLKQTFEHAGMGHVTTYINSGNII
                     FSSQERPNQELSLVLEQAILEDFSLPIRVIVRNMKEIQSIMEALPDEWANDTQMKSDVM
                     FLWDEINDITVLDKLPLKPGIGHVMYTPGAVLFSVSKEQVTKSGLTKLVGTKLYQQMTV
                     RNVNTTRQIYKLMQMAEQEELRDLDS"
     gene            complement(18969..20714)
                     /locus_tag="CPY53_RS06770"
                     /old_locus_tag="CPY53_06795"
     CDS             complement(18969..20714)
                     /GO_process="GO:0006935 - chemotaxis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1061: methyl-accepting
                     chemotaxis protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688156.1"
                     /locus_tag="CPY53_RS06770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06795"
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="WP_242211189.1"
                     /transl_table=11
                     /translation="MSNKLSDRTKKGKGLRDVKVTTTMISMIVISLVGLLIVSLVGVIG
                     MYQAKEGQGILYVDRFQHQTNILEVKSDFYNMRANYTKILDNKEYTDKQYKQVQKGKDS
                     VTTGLNEFSQRTLDAKEQKLYEELRGSIDTYFQDIEQIMAVKKNTGTYDTEERGRINKS
                     STAIVTMLTTISDYNNEQSANLYQNTQNEIKMRTIVLITVLALVLVVLITISFVAIQNI
                     RSRMSTITKYCEEITQGNLTAALDPALLKGNNEIAVIARAIQQMTDSTSMVITGVINES
                     RQINQLSDQTNLNMTDLNERIRDVSATVEQLSAAMEETSAYTENMNHSADEMQRAAEYI
                     SVKTQERAQSAYDTSVKAETLKQAASQSNKAAKEIYQKANAKMTEALERAKAVDQIRIL
                     SQSILEITAQTNLLALNASIEAARAGESGRGFAVVANEIRKLADGSKHAVDQIQSVTQE
                     VVQSVENLTTNAEELLHFLQTQVGKDYQLLEDTAGQYYTDAVEHTNTVNDLNATSKQVN
                     ETIQTMVRAIHEIATASEQSAISTQHIAENMVSSTEKSREVAHQSDQVKESAARLNELV
                     EGFKI"
     gene            21064..21648
                     /locus_tag="CPY53_RS06775"
                     /old_locus_tag="CPY53_06800"
     CDS             21064..21648
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821745.1"
                     /locus_tag="CPY53_RS06775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CPY53_06800"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_102998912.1"
                     /transl_table=11
                     /translation="MTNIQNQKQVYIIHGYTASPADHWFPWLQDKLQEDGVSVDILEMP
                     NSQAPKLNEWIEYLLQNIKVLHKDTYFIGHSLGCVSILRYLQQVNISEPLGGAVFVSGF
                     TDPVPSLPSLDEFTIDHLDDQQIMDSLKARAAIASKDDTIVPFALSKKLAEDMQADFHE
                     VDHGGHFLQSDGFTTLPMVYQVLIEMMNANE"
ORIGIN
        1 tgggtattaa taattcttcc aatagttgtt tcttcagaat caattaaatt aattggaccc
       61 ctttcgtctt tatctttctt tgttaaagcc acataaactt tatcgccaat tttaaaatct
      121 tgaatatctc gtcctatttg gtacttttcc tccttggtcc aaaaaccaga caataccaaa
      181 tagccatttc tcttgatctc tcctagaatt gtacctaaat ttatttttat ttgttcatct
      241 aaattatttg aagtaacttc cttatgttgc tccttgattt gtatctttat agtttccggt
      301 aacgatgaca ttaaatccat caattttttg ttatactggt caatttcgat ctgcttatta
      361 tcagttttcc catcatcccc agtgatatta cctttaccat ttatagataa aattctttct
      421 ctttctaata tgagtttatt tatttcttct aatgtttcta tttcatcacc aataatgtct
      481 ccccaatccg caattgatga tcctatgctc tgtttgattc catcagtaat tacaagtaac
      541 acctcgaaat cactattaaa atctgaatta attttcattt tttcgttaat ttttccaatt
      601 aaattcaaaa cacttttatc cagctctgtc atccttcgat atgcagcaat agcaaatctc
      661 ttttgactct tgatgaattc attttgaaag gtaactcttg caagaaatat ggagaatact
      721 gcagaaaaaa taaattgaag aacatttaac aaggctaact caagttttgt tgtttctgga
      781 ttcacagtat ataactgtaa taaaacaatc cctatagcta ttattcctag aacaattgtt
      841 gtaataatat taaagatatt actttgactc ttcttcattg atattaaacc ccattctctt
      901 cgaatatttc gcctaacgtt tctgtattca tgagcccctt caggggttgt ctgctgaaat
      961 gcctctccga aatccatctc acagaccaag gctccaacgg agctgctgct tgaatattat
     1021 gttatgcgat tcctctgtcc tctccaaatc aacgttccaa agctttgctt gcttctgtta
     1081 attcatcatt tgcctctaaa tattttaatg ttttttcaat attgtcgtgg ttcattgttt
     1141 tcattataat tagatgttta atattaaatc ctggtaattc cttttctttt ttaaagtgat
     1201 ttactaattt ttgaggggtt gtcaccaaac tccaccgttc acttccatcc gaaaaagtaa
     1261 gggtcacctc caccaaatca aactcctttg ggtcatcatc aaacttccat gtttctaaat
     1321 aaggcatttc tatatttcct tcaataaaat aagcttttga tatccaaact cctttttcat
     1381 gatttccaat gattctatac ttgtccccat cctcattttt tacgatgtat ttattccctc
     1441 ttgtaagtgc atgatcataa acacctatac tcctacaagt tatgattcgt ccatccatga
     1501 attcacttcc acatatcatc tttagtttac tgaggtttcg cataacgttt ctgcattcac
     1561 gacgtcctag cgctttaagg accgaaggtc cggctgccgc ttgcggcagt taggcggtgg
     1621 gatgtgtctg cctgattcac ttccctgaaa tgcctcgggc agaccaaggg ccgggttcgt
     1681 cccggcccga cgcgtcgaat gcgatgttag gcgatggtgc tggcatctct gaaaaattat
     1741 acaaataagt taaagttctt aaatgccacc aacttattag gtttggtctt tcctttactg
     1801 gtattgcata tctgatagta tttttcccta gttgaactag ggagattgtc ccataaatca
     1861 ggggaaataa agacattttc aatatataga gcaattaagt tagaaatcgc aatcctttgc
     1921 tcctccattg ataaagtcaa tatttgatct ctaataaatc gatactttga cttatcttta
     1981 gtaaaataac tcattaaaac ataagtcttt cctgcatgtg gaaaaaatgt gaaaaagaat
     2041 ggagaaatat acgaattcat tttattaatt gtttttcctt cattgtcttt ttctataaaa
     2101 aacatagaag tagaagcaaa gccatattct tgaggccaaa ttagaacatc tgtcgtaatt
     2161 ctatcaaacc tactgttatc taaatactta ttcattataa ttttgtagtt ctcaattact
     2221 ttcaaatgat catcatataa ccggtatctt gctcccaatt cagtatgtaa attacgggga
     2281 tcatcttcaa ctctcgcttt aattaattga tatgcactat atctctcgta ataaccaagt
     2341 gcaaaagccc tgtaagcaaa tagaaagtta tgttggctat cagttggttt ataatcgtta
     2401 ttctcaattg gactaaatat actcgaatca tgatgattac aaaaaccggt aaaggtagaa
     2461 gccttgtccc ttcctacttt aaataatttg aagtttcctt tatccagata tacttttgaa
     2521 aaatcaatag ccattacttc actgttgcgt gagagtttat taagaattcc attgttttgt
     2581 atcgaatgag ccctactaat tctattgcaa aattcatctt gatgaataca acctgaaaac
     2641 aagttattgt ttctcatctt gttaaatttt atgttttctt taatatttga attcatttga
     2701 atcacctttt ttatagattt taatgatttc agcactttcg cctaacgttc ttgtattcat
     2761 gacccagcgc atgctgggtg tccggcgact gccggaccga ggacgaatgt ccgatgcatg
     2821 aatattatgt tatctgctgt ttctcacttc tttgactaaa cagtaagcaa gttttttaac
     2881 gaccattcat tatcatttcc gtctttcgaa acaaaccaaa tatgagtgta tttttctggc
     2941 ttgtatattg catttttatt tctaagaaaa tcactcattc cgaatatagg agaagcgttc
     3001 ctaattaaaa gcgctattgg atatgcagca tcatacttct ctatcttttt ttccttctgt
     3061 ttcagtagtt cattaagaac ctgcatatag cttgctgaat tttctaatcc atgcatttcc
     3121 tcagccgatc ttccaaataa cattttagct tcgtcggcat cgtagaatag gtgagttact
     3181 tctagaccta ctaatccatc ttttatgctc tttaagatat aatctggacg ctcacgtctc
     3241 tctattactt ctaagtgatc ttcgcgattt aaattataca aatctacaaa gatgctaacg
     3301 gcagcttctt ctaaggcaga tttttcatca tcatgatttt tcattacttc tccctgccta
     3361 aatgtatttg agaaattgca gataacgttt ctgaattcat gaaccccgaa ggggttgtct
     3421 gttgaaatgc ctacttgaga tccatctatc agaccaaggc tcctttcgga gccgctgctt
     3481 gaatattatg ttagctgaat taactgactt cattgaattt actgtagccc atccccttca
     3541 agaataaatt tcaagaattt ctttccgtac aatgaaattt caacatcttt tctatcttta
     3601 tctgaatcac ttccaccaat gtctttcaat gttttcttta tatttagtaa tccattgttc
     3661 tctaatcttc tatctatatt tcttatcaaa ccatgttcgt cacttccttg gacaaaagta
     3721 atagtttctt cagtcaatcc ggctaaataa aataatcttt tcagatccag gtatcttaaa
     3781 ctccttaaca tatcataaaa gttaattatt accgattcat tactattctg ttcaataaaa
     3841 atattttcaa agccattaag tattaaattt atttttgcat cttcatgttc ttcaaacaaa
     3901 tccgaaaaga taattcggaa aatcctttga ctgatatatt cggatgataa tacagaatct
     3961 gctgcaaggt ccgatataaa attaattttt ttgtcatgct ctttgaatct gcgaattagc
     4021 cgattaattt taactgtctg aactaatttt cctatgtaag gcacaaaatc aattccattt
     4081 tctaatattt gcccaaagta tggatttatc atccctcctt cttgaattac ttcattaaag
     4141 atttccttat ctgtcattca atatcactcc ttgttctctc agatatttca gctagcgttc
     4201 ccgcattcct gacgttcaag cagcttaaga gaccagaggg aacgggtcat catacttagc
     4261 tggttgaatg tatcgcctga attaacttcc cgaaatacct ctcggcgatc aaggagcgac
     4321 cgtgacgatg taggaatgta ttgttataag atgtgttagc cttctccgat acatcctatt
     4381 caaataaatg ccctaaaaaa tcctcttgca acttttgtat actttcctct aaaagactta
     4441 taaattcttc agcccttaat tggtatgtgt ttactttatc tcttataagt tttatgtctc
     4501 ctgttccaat gtaatcattt ttcaaatccc acagagcctg atcaagttca attcctgatt
     4561 gtctaatttt tgtgtacata tcactatact gttttattac aacaatacgt tttaaataaa
     4621 aggtctctag tgcactgtga catttgaccc aagtttttgc gatctcccaa aacctctcat
     4681 caaattctct tattcttgtt tttatatcac tatttaggta tctgtcatca aatggaatac
     4741 taagtgttcg attttctttt gtattctcga gaaattgaaa aagcaattcg ataaattcat
     4801 cattagcttt taatcttaaa tctcttttga atttttctgt ttcattctta tatgcagctt
     4861 tcctctgtct gttaacatta ataaaagaaa ctaacagacc ggctagtgag actactaaag
     4921 caatataaga gatgtttatg gtcttcatgc tctatccttc cttttctttt atcttgctgg
     4981 catttcttat aacgttcttg tattcacgac acctgacgtg ccaggtgtgt ccggctgcct
     5041 ctgcttctct gaaatccctc agccggaccg agggcgtatg cccgatgcgt gaatattatg
     5101 ttatacggag tcatcttctt ctcgagaaac acaaactaat gtccatgcat ttcttgaaaa
     5161 gacattatca atggctatga tattcattaa gttatatatc tccattggtt tagagtataa
     5221 ttccataaat ttattaacgg taacaggcaa aaaatttctg gttgatccat gccacgacca
     5281 catatctcta tttttaaatt ctttcatgat attcaatttg gtttcataga taaatctata
     5341 tggatcacct ctccattctt ctggaagatg agataatatt tcattcagtc cggcagcaat
     5401 ccaaatcagg gcttgctgct cattactttc tttgttgttc cataacattt cagctgttcg
     5461 attaaaaccg actactgtat cccaatcagc acctaaaatg cctcgatcat ttagtttctt
     5521 tgttctatat tcaacttcat tggttggcca ccaatctatt atttcagttc caatattaag
     5581 attaggattt aactgtggtt gtattttaat ttttttaaaa cttagttcgt caatagatct
     5641 atagctatac tcttcaataa agtgcttcca gtatgaatag acttctttcc atgaaaaatc
     5701 attagaattc atatttggtc tcctcttatg taagatgatt tcgtataacg tattatttac
     5761 gaacttccga aagaatgctc tcttcgccat attcacgaac ttcgtgaatc ctgcactttt
     5821 ctccttattc cggcactttc tgcgtttcaa tcctcctgcc cgctcatccg atccaatgga
     5881 ctttgaatcc gcccaatgtc ccgtctgctc acatgtgtat accgctccgt cgttcgcaca
     5941 ctctgatgcc ctagcagttc ctgaatatag cgaagatcaa tcccattctc cagcacatgg
     6001 gtcgcaaaag aatgccttag cgaatggata cttacctgtt tgtgaatgcc cccttcaagc
     6061 cagtgtcttt tcaaatactt tctgcgctga acgttccgtc aggtggcggc cttccctctg
     6121 ccctggaaac agccagtctt ctggctgctc cacccctata tacttctcga ccaccgcaaa
     6181 agccgcttcg gaaagcagcg tttgccgaac cttcctgctt cattccgata aagtaggtaa
     6241 tcttcatctc gcttgtctcc ttagtatatc agccgttcaa aaaattggaa atctatttcc
     6301 gcataaaaaa agggccttaa ggtggaaatt caccttatgg ccctgattct ttcggatcaa
     6361 attattgatt ctttaagttc aattttcatt atcataatta cttagaatga gactccgaag
     6421 acagcggaat agtgtaacgt taatctcttg cataaggata tgcgactaaa aagcgtagtt
     6481 tctcaccatt tttttcaggc aaactgcttg tattacaatc atatataaag aacaacgaat
     6541 tatatttacc atctatttta ctcaaatcat gtaatagtgg agataaaaaa gaatcaacat
     6601 aggaaacatc ttttatacca tcatctgccc catccatcag aaagactcct tcagcaaaat
     6661 cttcgtcaaa atcatctatt tcatgatcat tcaaaaaacc gctaaaaaca tcctcattct
     6721 catcttccgg gtatttgatc tcaacatatt caaacaactc atcttcagag gcaaagtgac
     6781 cgtaccagac ggacaccata tttttttcaa agcaattcat gtcttcaccc cgctaatatt
     6841 tcattttata cgtatggtct atctctatcc cgcactaact accatgccct ctacccctca
     6901 acagctgttg aagctaaaaa gcccgcgctg atcgcgggcc ttgctgtata taagtcaaaa
     6961 tcatgcctag tagacttgtt actccacctt aaactgcttt aattcgtctt gcagcttagt
     7021 ggacaattgg tttaattgtt tggatagttc agcaacctgt tcgaagctct ccaattgttc
     7081 ctgcgtgctg gcgctaacct cttcggttga agcggaattc tcttcggtgg tagaagagat
     7141 gatctctagc gcctgcaaaa tctcatcttt atgcttgtgg actttggagg tgttggtgct
     7201 gatctggatc attcgcaatt tcaaatcttc caaatccttg ttaatgctaa agaatacttg
     7261 cttcgtgtcc tctaccgatc tggcattttc ttctgcaatt ttcagaccgt gaacggtgtg
     7321 ctcaaccgat acgctggttt tttcttcaat gacacgtact ttcttgtaga tttcctgtgt
     7381 cgcccgtgcg gtctgctcag ccagcttgcg aacctccccg gcaactaccg caaacccttt
     7441 gccctgttct cctgcacgtg cagcttcaat ggaagcattg agtgccagca ggttggtctg
     7501 cgttgcaatt tggttgaccg tatccacaat gctcgaaatc tcatgacggc tcaaatcgat
     7561 atcctgaatg atagccgaca tcgcttgtgt ggagttatga ttttcttccg cccatttgga
     7621 tagttgatct actactgcaa gcccttgtcc gctttgttcg gctgaggttt gcaccattgt
     7681 ttcgatggtt ttggcatcat tggcaatttc gtcaatttgg ccggataatg ctccggtttt
     7741 ttgtaaaatg ttatccgtct cgatggattg gtagtttgtc gcattggcaa tttcattaat
     7801 tgctgtcgca gtatcgttca tcgtgattgc ggttctggaa gaaatggatt gcaagtcatg
     7861 agaagactga ttcaagactt gagctgagcc gcccaccatt tggagcatac cttgaatttt
     7921 ttgaaccata ttgtgaaccc cttgagaaat ttgcccgatt tcgttatggg aattcgtatc
     7981 aaacggaacg gtcaaatctc cattttcaat cagtttgatt ttggcaagca atttcgggat
     8041 tgctcttaat agataacgga gcgttatata acagattacc acgagcagaa tggtggctgc
     8101 ggcaaaaccg ccaatcgtaa tccaggtaaa ggttcttaat tctgagagcg cctcttgttc
     8161 agaaatggtt aagcctacgg accatcccgt atctttactg gttgcatacc caatgtaacg
     8221 acgctcgcca ttatcattaa tgagctgtac tccagactcg ccagcaatca ttttcttacc
     8281 gatctcgcca agatcacctg tgctttcgtt aatcttttct ttcagcactt tattttgatc
     8341 agggtgatac aaaatatcac ctgttttgga tgcaagaatc gaatagcctg tgtttccaag
     8401 cgaatagctt tgcataacaa cggggatatc tttgaaggca atatcgacag cagcaaatcc
     8461 gattaattgg ttactgctat ctttgattgg atagaaaatg cccatgacca cattccccga
     8521 attgacgtcc ttatagggtt ctgagtagta caaaccgtct gcttcaacag ccggcttgaa
     8581 gtacggacgc gaatggatat cgaaatccgg tttggaagca gcaccatcat tttgtagaaa
     8641 gaagccttta ccatgtattc ctgcaatcca ggcgtcggca aaagatggct cttccttgac
     8701 aatcgctgcc agagtcgctt gagttgccgc agcatatgga gaagttttca ccatctctgc
     8761 tgattcggtg gtttctatat attgtctaaa taaagtgttg gttgacattt gcttgactag
     8821 cgagcccttt tccttaaata acgcatcaaa ttgactgacg gtggcctgcg tcttggtctg
     8881 gagcatggcc tcttgctgct tgacaagcat actttgcgtg ctcgcataca tgaacgtccc
     8941 caaggttgca aagacgacaa cgataataac taacaagacc atggccaatg tgttggcgat
     9001 actggatgat ctgaatacgc gcttcttcat attttgtgac atgctgccat ctccccgagg
     9061 aatattgagc aaaaagctct tagataatat gtcggaagtt tgcagttgtt ttaataggtt
     9121 tttagtatac acaatttaaa gttttgctat ctgattcctc ataaattccc tcccagcctg
     9181 ctcggtaact ccagcaaaaa attagggcag cacaaagagc ctccgtcaga cgcaggctct
     9241 ttactaaaag ttataaacac gcagggttat gcggacttaa agtgtacgag caatcaagta
     9301 agctcaacct ctttattctc tatcgttaac ccaactgcat cgttgtgata catgtatcgt
     9361 ttttctcata tgtagagaat tccgtttggg ccgttttacc ttcatggttc acactaatgc
     9421 ggtaggtttt atctcttggc agccatagat caataaaacc attgggttgt gatttcatgg
     9481 cagcattctc catgatgata ttcccttcgg agtcgtgaac ggtcacattg aacgccccat
     9541 tttttatttc gccttggcaa ccggttagac tatgagttgc acaagggtgg gtctcttcta
     9601 catatggcgc aatcgaaaca aaaaactcgt tgtcaggcaa atcataattt atggtctggt
     9661 tattgtcccc tgtgaccatc aactgactgg aattaatgga agcggattga cctgttgcct
     9721 tgcctgcact gaaatcatgc accaactgct tgatatctgt tgtcccaagc ttgttcgctc
     9781 cttctttctg aaaatttcca gtaatcagat acgtgcccaa tgccgcaaca accaaccctg
     9841 aagcgaccaa gattcctttt ttcatctgga gttcatctcc ttgtccgttt taaatcatta
     9901 taagggagaa cgccccataa cggataaaat acggtactga agtcaccaga tattcacatc
     9961 tttgcttgtt tattcagaca tatctggggc acaattcttt ttaacgatcc cggttcacaa
    10021 tataattcat tagatgcttc agaaaagcga tattgcgtgg cacctctttt aatgcttcca
    10081 tggcaaggca gtagtgctcc cacatctctt tactggcacc ttcgtaacca aggatggaca
    10141 caaaattcga attattgtta tccgaatcct gacccacagg ttttccaagt aagagcgtat
    10201 ctccttccac atcaagcaaa tcatctttga tctgaaaagc aatccccata tgataggcga
    10261 atttctgcaa agcagcaatc tctgattcct cggtctgtgc aagcatggct ggcataacga
    10321 gacaagcctc gaacgccact cctgttttgt aaaagcacat catattcagc tgctccaagg
    10381 tcaaagcctt tcctttggaa tccagatcca tcgcctgacc catacacata tcctctgcct
    10441 tacgggccga gtattggatc aaggcaagca cagtctcagc attgaactgg ctcagtgatg
    10501 cttgttcccc gatggccttt tggatcagat atagaccggt taattccgca gtagcactat
    10561 tgtgcacctg atgtaatgtc tgacgccctc tacgggtaga ggcgttatcc tgggaaggca
    10621 aatcatcaaa aatcagggag gctgtatgca tatattccaa tgatcgcaga agaggtacga
    10681 ttgccgatgc gtctaatcca tattcattta cgcccatgac ccaagtcaaa ataggtcgta
    10741 tccttttccc atccccctca agactataat tggcagcatc aataagctgt tctttcatgg
    10801 cctcaatccc agaaggcttg gtaattttca attggttgtt aatctggtca cggattgttt
    10861 tgaccgtatt cataaagtct tctttttccc tcgaatcgtt cttcaaatgg gtaatcatct
    10921 ggtcccgaag cagcttatcc aaaaaatcta catcctctgc tttgcccacc atcttctgga
    10981 taagacgatt aaattccgga tttccggatg caaaaatccc cattatttca ttgtactttt
    11041 ctacacctac ccgttcttta taacgtttga gtccatttat tgcacggtcc agtatcactt
    11101 cacgagccat agcatccgag tcatacacgt tatgaatcaa gtgagaaatg accgcccagt
    11161 atagttcgaa gggattgatc aaatccgatc tctgatgatg atattttaaa taataggtat
    11221 agggtgtaac cgcaccatcc ctcatatcgt cggccatatc tgcaaaatca tcagcaagct
    11281 ggttatagat accataatag aatgtccgta gctcaaaccc ttcatcctca ggagcactaa
    11341 tcacggaacg gacaatcaaa cgggaagaag cagattttaa aataacgggt atataaagct
    11401 cttcattggt gtaattagct cgtgttagat ccttatcccg gtcgatatct tgagaatgaa
    11461 agaaaacata ggactgctcg aaaaaggttt gctgtgtgtc tggccgctga tgtgccttaa
    11521 tatactcaaa agcatccgag agctccgaat ggatatagcg aatgaacttc atatgatcgc
    11581 cggtccagtc gcctagttct ggcacagatc cattaagaag cgcggtacgt atcatatggg
    11641 aatattgttc tttctcttga acggtcaaca gctgagaatc gagcagatca tcaataaaag
    11701 gataggtcag cccataggaa tatccaagcc tgatggcttc atccagtctg cgcgaacgtt
    11761 cactaggtgt cacggcttcg tccatttctt ccattacatg cagaataacc ccaatgatga
    11821 ttttaatcag tttgcgctgg gcatgctctg catccatttc ctcaggaata tgagaagata
    11881 cagagttaag cttgttgatt agccagatta cagtggtttc gatcccttcc ttttgagacc
    11941 accgatacac ccccgctaaa ttcataaact ccggttgatc tctcctgtta gcatgggtgg
    12001 gtttaagcaa atatcttttt acgtcagcaa tgacgcgctg aatccgggtc tgtgtgtcgg
    12061 cagaatctag agccttgcct agatccctca tgtaaatata agagacactc cgcttcagat
    12121 aatcatccag tttccctgtg taactcagcc attgaatata tctgtagtaa tcccgggtat
    12181 ccggctttct cttattccgc gaaaagaagg ataaccatga agaagaatgg atatgattcc
    12241 ttttccatat atggatatct tctgtaagag aggtcacata agtcttatcc ttgacctgat
    12301 tatagagtga tgcaaaatac tgaagcgcct tctgctcagc cagctggtat cctgtatcgg
    12361 ctcgaaattt ttcattcata tgatgcatta cctcaacttc tcattttgtt taaacatggt
    12421 tgcatttctc cctaagggaa cgaatttgga tcatgttttt atctttatac ggaaaaaaat
    12481 ctgtgaagtt acgaatagat tatatccttc tatatatatg ctacaatttc agagtagaac
    12541 aaaaataatg atagggaggc ataaccttga gtattagtct aattaaaggg cagaaggtag
    12601 acctaaccaa aaataatcca cacttatccg tgctgaaagt agggcttgga tgggacccta
    12661 tgaggggtag aagcatggat attgatgcgt cagcgctgct tcttaatgag aacggcaagc
    12721 tgactcaaac gaaaaatcta gtatatttcg gaaacaaaaa tagcccttgc ggggccgtcg
    12781 tacatagtgg tgacaacttg acaggacatg gtgacggtga tgatgaagtc attactgtat
    12841 cccttcaaca actaccacct gaagtgcata gagtcgtatt tattgtgaat atattccgtt
    12901 ttttcagctt tggtagacgt aaggatttca gtatggtgaa caatgcttat attcgagtat
    12961 tggatgcgtt gcaagatgaa gagattctcc gatacaattt gacagaggac tataaaggga
    13021 tgtgtagcat ccgtgtaggt gaagtatacc gctatggagg ggagtggaaa ttcggtgcta
    13081 ttggggaagg cagcaccatt acctccctga atgagcttgt caaaacgtat gaataagtat
    13141 ttttggtgtt aaggaaaaac ccacgtctga cgtgggtttt tatactatct cttcaacagc
    13201 cagctgatac agcagagaac cttcacggag cagcaggcga tcttttctga aatcctgttc
    13261 atgcggttga aggaactttt gatcgtcatt taaaaagcga atgtgttgtc ctttgctcaa
    13321 gctgcctggc ttcacattct ttttcaagac atattgtcca ttcttgccat acccgccgtc
    13381 gaacaaaaag tgatatccat ctgtagccac cccggaacag ccggaaatcc tcggattcat
    13441 aaacgtaata ttcgtacggt cgctaccgga aatacgtcct aatgaaaaat ctgaatagta
    13501 ataaaaccag atttcctgtt cgctgactac gttcaaagca tagcaatcat gaatatctgc
    13561 cgcttggttc tcatatattt tgtgtccctc tttattccag gcgacaaggc cggaggaccc
    13621 cacaggctca ttccaaccat aattcccgaa tataccttca tcaaaataac tggtccagat
    13681 cgtaccttct tttgtaacct gaacactctg gataccgtct ccaagcagta gttcattcac
    13741 agtacgacct tcataatcaa taattttacc atttagatcg tattgatcag gtccgtaata
    13801 atggcatcgt gctccgacga gtaacaaata atcttgtaga ggctgtacat aatgatagtt
    13861 gaactgctgc ccctccaaac acacctcttg aatgtgatcg tctagaatga gtaccttgta
    13921 agtacgtttc tctttaagag aggcaggcgt gaacatcccc cgcactcgtt ctgggacttt
    13981 atcaatgagc aaaatataca cgcgtccatc aggaccaaat tgggtcgaaa cgatctcaaa
    14041 cccttctata ttattggaaa tatcgacaaa tgaatgaagc tgtttatcta gatgtgacaa
    14101 tgtagttcct cctctgagag atcagtaaag tgaagtttta tttgtattgg atttcatttt
    14161 ggcataacga caagtaactg aggagggtgg aagtatggcg atatgggtag taatcccaag
    14221 agatgagtca tcggcaaaat atagcgaaca aaaaaagctg ggttctgctt cataagaaaa
    14281 gcaacccagc ttgatcttta tagattttcc ccttagagtg tctggccctt gtcggccttc
    14341 tgccataaag cctcagtcag ctcatcaatc gtctctttca tcgccagctt ctcgcgccag
    14401 tgactcggga tactgcttaa cccataataa gcccctgcaa tctggccgta cactgctccg
    14461 gtcgtatctg cgtcatcccc cagatttacc gccagcagtg ccccctcttc aaatgaagcc
    14521 gaatggtgaa atgcccacag cgcagcctca agggaacgaa taacataacc gcttccttgg
    14581 atttcaggcg gctccttatg cttgtaagat ccctgaatga tttcttcaat ggctgccgaa
    14641 taagctgact ggtccttccg ccgccactta tagcagacat cgggtgataa catggattct
    14701 ttgtccgctc cccgcagacc tgccacaaga attgaagcaa gcgcggcaca ggcctccaca
    14761 ctttcgactg ctccatgggt ggtgcgcgag ctcagctcag cgtacatcac ggcctcttcc
    14821 gggcggttcg cataggccat ggcgacaggt gcaagcctca taatcgagcc attaccagca
    14881 gtcatggggt caacggaccc gctatacgga tctccagtgg cttcgaagcg atgcagtgct
    14941 gttctcgtcg caccaccgat atcaaagcac attcccgtgc tgctcatata tcccaggtgg
    15001 taccaattgg tgtagcgacg catctggtcc gctggatcaa agttatcctt ttgtaccata
    15061 ctctgcgcca aacataacgc catagacgta tcgtccgtcc actgccctgc cttcagccca
    15121 aatacaccac cgcctacaat atccgttaca ggttcgaatg tgcctggact gctaaattct
    15181 actgtggttc ccaaagcatc acctacggcc agtccagcga gacatccata aaaacgctcc
    15241 ttgttaagtg ccattttgat gtacactcct ttgtaattgt tatagctaat gcatatattt
    15301 ccatatcact aggaaggaag aatatccggt acgccattta ttcgtcgtag ctcaaggctt
    15361 tacaaccgct atctggatgt aattcaacga aaattcctgc ctcttgatgg taaatgagtg
    15421 gaaatcgctc cgtatctaca tgttcccgcg caccgcttga aagccgccat acctgaagcg
    15481 ggacttcttt tccccataag aataatcggt cgccgcaaac agccatatcc gcttggggat
    15541 atggataaat tccgtcttca tcaggcttac aatttagagg tgggatggca gaaagcacac
    15601 gtcggtaccc aggctgagtc atatcgaata ggacaaccgc cggttccact ccctcctctc
    15661 cccaatcttc ttcctccatt aaatcggcat ccatctgccc ccaaactgcc aatgtatcgg
    15721 gtcctgtcca gcatactggc ccatcccaat ctatagtttg ccaaagatgg cgaactgacg
    15781 gaccattctc cgattcccat ggattcagca gccaatcgga taatgaccaa gttcggacca
    15841 ctcctaaggg agcccatacc catcccgtat ccgcaatcca ctttccctct ggagaagcca
    15901 gcagccttcc atgaaaataa tctagataat gctcatcttt gctttcgctg ttataaaccg
    15961 gggtaggtct tgctgtcaaa ggcagccctg tttctacatc tgtcaaatcc agccggttcc
    16021 attccgttcc atgaacaaga atacatgcac cgtcttgatg tacaaatgcc aggggaaaca
    16081 tacttttatc gtagtggtat tcgtcccggg ataattgcat tttttcttga gcatggacta
    16141 aatcatacac tgcagcatgt cggccaaatc gattggagat ggctgcgtac ttgccgtcag
    16201 ggctggtaac cacttggaca ggttgcaggg gattgaaatc aggaatacaa atacgtgtac
    16261 acaattctgc gctgccagag cgaagctcta gcctccacag ttctgcttgt gtgttcaatg
    16321 ccagcaaggt tatgcttccc tgagagccac cttttacagg atgaatggcc gtaagacgtc
    16381 cgatagacgg tggtaaatca ggtaaagaaa cgtgatgaaa tggcatcatt taaccccttt
    16441 taatctggat aaataataat ttatacccgt atttgtgaag ctggatttat cgataaaaaa
    16501 tctgagttca agcaatgcag acaatacttt cataaaaaca cccggttttt tcttgcagaa
    16561 acatttaaaa tatgtaattt cgctaggatt acttttgaga ataaaatagg agtaattcat
    16621 catgatcata ttggagatga actgctctgt tggagattga tgttcattga tacagtcgat
    16681 cagcacctct agtaccctat ttttattaga gttgtaggct tgtataaaca tcgttacttc
    16741 tacaaacggc ttgttgaaat catcatacgg aaaatcatat acatcatgac tgcccaagat
    16801 gaagttgacc aactggcctt gcaaaatttt tattttcccc agcgttgctc gggtatccat
    16861 atccatctta tttttgttaa tatgctcatg caaaatatca attagaatgt gcaaatcata
    16921 ctgctgtccg tcttccatac tgtacagtat cttattattt tcaatcgtta gacgatcata
    16981 aatgtcatct cctaaaccca attcaaataa gagaaggtga agaaaaaaca gcctatcctg
    17041 agtaagtgaa aattcattcc ctctctctgc tagatgtaaa acttgatatt gataataaac
    17101 acaacataag ttttttctgc aataagcaac atctttatgt atatcaaaca tgttaaaaat
    17161 aagcgcaagc aatcgaatca gacgttcagc atccgttacg cttagaatgg gatgatccat
    17221 ttttgtaaat agcgacctgt caaataaatc atgccatcgc actaaagaaa tatgatcctg
    17281 ctcatttata ttcagagtta atattcttaa attttgctct tgatcaggat aggaataaat
    17341 tagatcttca tgattcaaat cagaaatgcg ctcattaaag taggctctta atttgtaatc
    17401 gtatatttca gaaaaagaca tttttctcct ccttacacct tattttcgaa ctcctatatt
    17461 gtaaaattat tctggatcga ctggcaaggt ggcataatta cagaaacata tgttcttcat
    17521 ttctatatta tgatatctta atgctaaaag taaaatgtga tgtcgcaggt catagcctac
    17581 gactagaaag gaatacacac ctatgaaaca gttaagcgaa gcgcttaccc ggtttgtaca
    17641 ccagcaaaac ttgtataatg aagcctacgg gctgttccaa gaccacgata tccagccccg
    17701 ttcagagagt ataacagatt gctgggacaa gcgggttcct gtatcccctg agctggagta
    17761 tctgtatagc tactatgaaa tgatcgatgc caaggcagcg ggaacacaca aattaaaaaa
    17821 cgcggcagtt gaagttgggg atgccgcagt tctctttttt gtcgcaccag aacatttata
    17881 tcgccaacag ttgggttatc gctttattac gtctgatgag cttgttcatg agtcatcttc
    17941 atggccatcc catcatgttg taattgccac gtttaatgac gatccagtca ttgtcgatac
    18001 tagcgcaccc ggttcgcctg tatatgctgc aattgagagt ggtggggcgc agcaggtggc
    18061 tgactcttta gctaacttct ttacggctct ttccatcctg attgaaggtg cctgtacctt
    18121 taagggagaa ttgatagatg aagatacata cgaaaccaaa gcagcatata tcgagcacgt
    18181 aaaaccattg ctgcatcatt tgttgggcga aaaccaaacc acgtatttgc tgaattacct
    18241 atccttttgt tagaaatcct attggttaaa gagaggtggg gctttttatg atctatatcg
    18301 cattactgcg gggcatcaat gtcggcggca acaacaagat cgagatgaag aagctcaagc
    18361 aaacgtttga acatgcaggt atggggcatg tgacgactta cattaattct ggaaacatta
    18421 ttttttccag tcaggagcgg cccaaccagg agctatcgct cgtattggaa caggcgattc
    18481 tggaggattt tagcttaccc atccgtgtca tcgtccgtaa tatgaaggag attcagagca
    18541 ttatggaggc actgccggat gaatgggcta atgatacaca gatgaaaagt gacgtaatgt
    18601 ttctgtggga tgaaattaac gatattaccg ttctggacaa gcttcctttg aaaccgggaa
    18661 ttgggcacgt catgtatacg cccggggcgg ttttgttttc tgtcagcaag gagcaagtca
    18721 ccaaaagcgg attaacgaaa ttagttggca ccaagctgta tcagcaaatg acggtgcgga
    18781 atgtgaacac aacccggcag atttataagc tgatgcaaat ggctgaacag gaagagttac
    18841 gagatttgga ctcctgactg gatgacgaaa gcaatctagt agagtctgct caaaaaggga
    18901 gccttcttac ggctcccaac tgtttttctt cgtccttcat ttaaataccc atcaccgtat
    18961 ggtcctcgtt aaattttaaa gccttcgacc agctcattca gtcgagctgc gctttccttc
    19021 acctgatcag actggtgtgc cacttcacga gatttttccg ttgatgacac catattctca
    19081 gcaatgtgct gggtagatat agcagactgt tcgctggcgg ttgcaatctc atgaatcgct
    19141 ctcaccatag tttggatggt ttcatttacc tgcttagagg tggcgttcaa atcattgact
    19201 gtgttcgtat gctcaacagc atcagtgtaa tattgtcccg ctgtgtcctc aagcagctga
    19261 taatccttgc ccacctgggt ttgcaggaag tgcagtaatt cttcggcatt ggtagtcaga
    19321 ttttctacag actgcacaac ctcttgagta acactctgaa tttggtctac cgcgtgtttg
    19381 gagccgtctg ccaacttacg aatctcatta gctacaaccg caaaccctcg acctgactca
    19441 ccggcacgag ccgcttcaat agatgcattt agggccagca aattggtttg tgccgtaatt
    19501 tccaagatag actgagaaag tatacgaatt tgatctactg ccttggctcg ttctaatgct
    19561 tctgtcatct ttgcattagc cttctggtaa atttccttgg ccgctttatt ggattgacta
    19621 gccgcttgct tcaacgtttc ggcctttaca cttgtatcat aggcagactg agctctttct
    19681 tgagttttga ctgagatgta ctctgctgcc cgctgcattt catccgcaga atgattcata
    19741 ttttcggtgt atgctgaagt ctcctccata gctgctgaca gctgttcgac cgtggcggat
    19801 acatcgcgaa tccgttcatt gagatctgtc atattcagat tcgtctgatc gctaagctgg
    19861 ttaatttggc gcgactcatt gatcactccc gtaatgacca ttgaggttga atctgtcatt
    19921 tgctgaatag cacgagcaat gacagcgatc tcattatttc ctttgagcaa ggcaggatca
    19981 agggctgccg ttaaattgcc ttgggtaatt tcttcacagt atttcgtaat ggtgctcatc
    20041 cgagaacgaa tgttttgaat ggccacaaag gagattgtga tcagaacaac cagcacaaga
    20101 gccagaaccg tgatcaacac aattgtgcgc attttaatct cattttgtgt attttgatat
    20161 aggttggcgg attgctcatt gttataatct gaaatggtag tcagcatcgt aactatggcc
    20221 gtactagatt tattaatccg acctctctct tctgtgtcat aggttccagt attttttttg
    20281 acggccatga tctgttcaat atcctgaaaa tacgtgtcta tactgcctct tagttcctca
    20341 tacaatttct gttcctttgc atccaatgtc ctttgtgaaa attcatttaa cccggttgta
    20401 acactatcct ttcctttctg tacctgctta tattgtttat ctgtatactc tttattgtcg
    20461 agtatttttg tataattggc ccgcatattg tagaaatcac ttttgacttc aagaatattg
    20521 gtttggtgtt gaaagcgatc cacatacaaa ataccttgac cctctttagc ttgatacata
    20581 ccgataaccc ctaccaacga tacaatgagc aaacccacca agctgatcac aatcatggag
    20641 atcatcgttg ttgtgacctt tacatctcta agcccttttc cttttttcgt cctgtccgat
    20701 agcttgttac tcatccaaac ccctccagct cgtctatggt taatagttca cgctgctctc
    20761 aactttcacg agtactccga tccccccttg atgctgccct ccaaacaaca atatgaagta
    20821 gattacaaaa cgtgatgcta tatatatcgg tagaaagcgc ttaaatttat aagtcaaatt
    20881 acagtactgc aaaaataatg aatattataa caggcaaatt tatacatgga cttgctacgt
    20941 aaatccacaa ttttaatact tataagcatg gggagtttgg taaactagag gggaatgcct
    21001 gcatgaagtg aggcacatat gcaaattaag ttctaaacac tggatgatgg gagagaacgt
    21061 attgtgacaa acatacaaaa tcaaaagcaa gtatatataa tccatggata caccgcttcg
    21121 ccagcagatc attggtttcc ttggttacaa gacaaattac aggaagatgg ggtttcggta
    21181 gatatactag aaatgcccaa ctcgcaagcg cccaagctta atgagtggat tgagtatcta
    21241 ttgcaaaata ttaaagttct acataaagac acctatttta ttggtcatag cttgggatgt
    21301 gtatccatat taaggtacct gcagcaagta aatatctcgg aaccgctggg gggcgccgtg
    21361 ttcgtttccg gttttactga cccagtgcca agcctaccat cattagatga gtttacaatt
    21421 gaccatttgg atgatcagca aattatggat tcactaaagg cacgtgcagc tatagcttca
    21481 aaggacgata cgattgtccc ctttgcactt agtaagaaac tagcggaaga tatgcaggct
    21541 gattttcacg aagtagatca tggggggcac tttttgcaaa gtgacggttt taccacctta
    21601 ccgatggtat atcaagtgtt aattgaaatg atgaatgcaa atgagtagca tctcaggaga
    21661 gccttgtgtc aaaaaaacaa cgccgattga atccgtaaac ctagctacta tttactttta
    21721 gcaatatgat aacaagcccc gatgataagt tattccatcg gggtttgtta tcatttgcta
    21781 tggccttctt tactttattg ttaggtcttc aatttaaaac ccagtgtgat aatttcatgc
    21841 ggctttacag actgaagcaa ctcattagaa gaatccacta cgatgtcttc tcctggttct
    21901 tcgaggatat tacttttata aaaatcgtac tggtgcggcc cgggcttgat aattaattcg
    21961 gctatactat tgctcatatt gtaccagcgt aacagcacat cccccgacag ctcattcatt
    22021 ttcatagagg aaaaggcaag ctccgtgctt tgccaatcaa acggcacata atctggagca
    22081 actgtacccg catgaatccc tgtttgtttt acaatccaag gaatttggta ttgataggct
    22141 tctgtatacg cgccggactg aataccgtcg ccatcatgtg gaatgatttc cagacgagcg
    22201 gtgtgctcac ctgggcactg cgcttccggc gtcgggaacc atccccaatc ccccagctcg
    22261 ccaactgagc gaagcagcgt tattgcaatc gtgttacgtc catcacgcat gatttcatat
    22321 tcattcaacc cgagattagc tacggtcaga ccggtttgtt ctccgcttac atccacaaac
    22381 gcctgctg
//
