LOCUS       NZ_CP061870            21612 bp    DNA     circular CON 25-MAY-2024
DEFINITION  Bacillus subtilis strain FX-1 chromosome, complete genome.
ACCESSION   NZ_CP061870
VERSION     NZ_CP061870.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4266037)
  AUTHORS   Huang,S.
  TITLE     Identification and cellulase producing ability analysis of Bacillus
            subtilis FX-1 based on Genome-wide data
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4266037)
  AUTHORS   Huang,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-SEP-2020) Technology Innovation Center for
            Exploitation of Marine Biological Resources, Third Institute of
            Oceanography, Ministry of Natural Resources, 184 Daxue Road, Xiamen,
            Fujian 361005, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. 0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 490.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022647025.1-RS_2024_05_25
            Annotation Date                   :: 05/25/2024 05:42:04
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,743
            CDSs (total)                      :: 4,620
            Genes (coding)                    :: 4,349
            CDSs (with protein)               :: 4,349
            Genes (RNA)                       :: 123
            rRNAs                             :: 11, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 11, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 87
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 271
            CDSs (without protein)            :: 271
            Pseudo Genes (ambiguous residues) :: 0 of 271
            Pseudo Genes (frameshifted)       :: 166 of 271
            Pseudo Genes (incomplete)         :: 103 of 271
            Pseudo Genes (internal stop)      :: 45 of 271
            Pseudo Genes (multiple problems)  :: 38 of 271
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:12:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4140100
            Orig. end                         :: 4161712
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP061870.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="9"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     gene            complement(213..3893)
                     /gene="narG"
                     /locus_tag="IE382_RS22270"
                     /old_locus_tag="IE382_22170"
     CDS             complement(213..3893)
                     /GO_component="GO:0009325 - nitrate reductase complex
                     [Evidence IEA]"
                     /GO_function="GO:0008940 - nitrate reductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009061 - anaerobic respiration [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="narG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391609.2"
                     /locus_tag="IE382_RS22270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22170"
                     /product="nitrate reductase subunit alpha"
                     /protein_id="WP_242304439.1"
                     /transl_table=11
                     /translation="MKKKKRSPLFRRLNYFSPIEHHSNKHSQTTRDDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQEHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWLLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFYDW
                     YADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAKVI
                     SISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTDFP
                     FLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDGQQ
                     KWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLNGEE
                     TYVTTVFDLILANYGVNRGIGEQQAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREFAQ
                     NAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLRPA
                     EGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRYKHHADYN
                     VLAARLGWLPSYPTFNQNGIDLYKEAEKAGAATPEDVGVYVASQLQEKKLKFAIEDPDN
                     EVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAPEG
                     KLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESKSD
                     WDIFKALSKAVSDLAEEVNMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAIPG
                     KTMPNIQVVERDYKHIFHKMTALGPNAALKPSGTKGMSWSIADEYESLKKRLGEITSDS
                     VAKGCPNISEAKQAAEAVLTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECFTF
                     EQITAQPKTVITSPAFTGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMMEFG
                     ETMATFKPILQHRPFLSKRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGGPT
                     VWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPGTK
                     LTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDWLE
                     D"
     misc_feature    complement(3959..3974)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3983..3996)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    3983..3997
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.64"
                     /tool="antismash"
     gene            complement(4084..4560)
                     /gene="arfM"
                     /locus_tag="IE382_RS22275"
                     /old_locus_tag="IE382_22175"
     CDS             complement(4084..4560)
                     /codon_start=1
                     /gene="arfM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391610.1"
                     /locus_tag="IE382_RS22275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22175"
                     /product="Crp/Fnr family transcriptional regulator ArfM"
                     /protein_id="WP_003243032.1"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNGTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     misc_feature    complement(4618..4633)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            4704..5423
                     /gene="ywiC"
                     /locus_tag="IE382_RS22280"
                     /old_locus_tag="IE382_22180"
     CDS             4704..5423
                     /codon_start=1
                     /gene="ywiC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391611.1"
                     /locus_tag="IE382_RS22280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22180"
                     /product="YwiC-like family protein"
                     /protein_id="WP_029726074.1"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRTFAYWSWGYHLLLPFLSALFGAGWSFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     gene            complement(5455..6171)
                     /gene="fnr"
                     /locus_tag="IE382_RS22285"
                     /old_locus_tag="IE382_22185"
     CDS             complement(5455..6171)
                     /codon_start=1
                     /gene="fnr"
                     /gene_functions="regulatory (smcogs) SMCOG1133:
                     Transcription regulator, crp"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391612.1"
                     /locus_tag="IE382_RS22285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22185"
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="WP_003227573.1"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESVNRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     gene            complement(6270..7457)
                     /gene="narK"
                     /locus_tag="IE382_RS22290"
                     /old_locus_tag="IE382_22190"
     CDS             complement(6270..7457)
                     /codon_start=1
                     /gene="narK"
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391613.2"
                     /locus_tag="IE382_RS22290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22190"
                     /product="nitrate transporter NarK"
                     /protein_id="WP_014478287.1"
                     /transl_table=11
                     /translation="MINRQHIQLSLQSLSLVAGFMVWVLISSLISQITLDIHLSKGEIS
                     LVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWISIADSLFDLIAGGFF
                     LGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAAPVIAQAVGWKSTVQ
                     MYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLSLFYFITFGAFVAFT
                     IYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSPLRILMFVFAGLTLS
                     GIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGIANGIVSAMGGLGGF
                     FPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKTHTERNSQSIN"
     misc_feature    complement(7522..7537)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     gene            complement(7593..9263)
                     /gene="argS"
                     /locus_tag="IE382_RS22295"
                     /old_locus_tag="IE382_22195"
     CDS             complement(7593..9263)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="IE382_RS22295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22195"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_041334658.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLEFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9260..9688)
                     /gene="ywiB"
                     /locus_tag="IE382_RS22300"
                     /old_locus_tag="IE382_22200"
     CDS             complement(9260..9688)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="IE382_RS22300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22200"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_003243604.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVTGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9895..9910
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="IE382_RS22305"
                     /old_locus_tag="IE382_22205"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="IE382_RS22305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22205"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 9.7e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="IE382_RS22305_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="IE382_RS22305_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="IE382_RS22310"
                     /old_locus_tag="IE382_22210"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="IE382_RS22310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22210"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="IE382_RS22315"
                     /old_locus_tag="IE382_22215"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="IE382_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22215"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_041334655.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1081.0, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.5e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.6e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.1e-44, bitscore:
                     150.9, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.7e-06, bitscore: 24.6,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-21, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.6e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.8e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIAHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_IE382_RS22315_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="IE382_RS22315"
                     /locus_tag="IE382_RS22315"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="IE382_RS22320"
                     /old_locus_tag="IE382_22220"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="IE382_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22220"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_041334652.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGI
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="IE382_RS22325"
                     /old_locus_tag="IE382_22225"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="IE382_RS22325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22225"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_003227564.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKMREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="IE382_RS22330"
                     /old_locus_tag="IE382_22230"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="IE382_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22230"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_038829818.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMVFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCISAALMPAATLPLCAVHMLWAVIIDFPVFLQAPPQQSKMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVVYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADEKRPSFSWQTEQQLWSGFSKYRSYLFCLPLFLATLAG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="IE382_RS22335"
                     /old_locus_tag="IE382_22235"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="IE382_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22235"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_080015532.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 5.7e-05,
                     bitscore: 21.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDAFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALLKTFADLSFPS
                     SLSFEAVEKARNELLLRIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFLDATDFIVDLVSQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVITRYD
                     VMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /gene="albF"
                     /locus_tag="IE382_RS22340"
                     /old_locus_tag="IE382_22240"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="IE382_RS22340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22240"
                     /product="pitrilysin family protein"
                     /protein_id="WP_017696258.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 9.6e-13, bitscore:
                     46.4, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNDQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHAERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLWVIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQVAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIHVSQKEAIRQ"
     gene            16237..16938
                     /gene="albG"
                     /locus_tag="IE382_RS22345"
                     /old_locus_tag="IE382_22245"
     CDS             16237..16938
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="IE382_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22245"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_029318695.1"
                     /transl_table=11
                     /translation="MKKSTVFTLLLLLIGMAAYSFGWVQAVAEAAAQYVQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDSYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFSISELLFLIILATIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16944..18320)
                     /gene="ywhL"
                     /locus_tag="IE382_RS22350"
                     /old_locus_tag="IE382_22250"
     CDS             complement(16944..18320)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391624.1"
                     /locus_tag="IE382_RS22350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22250"
                     /product="YncE family protein"
                     /protein_id="WP_041351296.1"
                     /transl_table=11
                     /translation="MKKNDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEAS
                     AAVTWSTDNVSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGA
                     VSVIHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVTGTLVLPPSPDPQ
                     SYVFTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVID
                     NKTLTIINTITVGGGPRKIEFDPKDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFA
                     LDPNGQYVYTANGSSWSVDKYDINTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELW
                     PKGVTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTAR
                     QRIIANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVTVIPVGAGPSAIAM
                     "
     misc_feature    18287..18304
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18359..19714)
                     /gene="ywhK"
                     /locus_tag="IE382_RS22355"
                     /old_locus_tag="IE382_22255"
     CDS             complement(18359..19714)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="IE382_RS22355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22255"
                     /product="YncE family protein"
                     /protein_id="WP_242304441.1"
                     /transl_table=11
                     /translation="MRKNKLSFKVKAGAEQEECLCFCEEEASREAMFQAPIELPEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVLGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLHDSFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     gene            complement(19711..19941)
                     /locus_tag="IE382_RS23755"
     CDS             complement(19711..19941)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="IE382_RS23755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_043858872.1"
                     /transl_table=11
                     /translation="MQIPPFLILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSF
                     YPQQFVQANTLPFHILLYLREQCMSEKEVKE"
     misc_feature    19895..19911
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19944..21089
                     /locus_tag="IE382_RS22360"
                     /old_locus_tag="IE382_22260"
     CDS             19944..21089
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="IE382_RS22360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22260"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_017696253.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            21073..21192
                     /locus_tag="IE382_RS22365"
                     /old_locus_tag="IE382_22265"
     CDS             21073..21192
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="IE382_RS22365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="IE382_22265"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_014665774.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
ORIGIN
        1 gctcgagctt tccttttttc aatgtccagc cgcctttata tttgtcctgg tcctcccatt
       61 gcttcgggta gccgatgccc ggctttgttt ctacattatt gaagtacata tattccgcac
      121 cggtacggtt tgtccatgtg tttttacagg tgacgctgca cgtgtggcag ccgatgcatt
      181 tatccaagtt catgaccata ccgatttgcg ctttaatctt caagccaatc gacctccttc
      241 agcttgcgga tgacgacatt caggtcgcgc tgattccccg ttgggccgta atagttaaag
      301 ccgtagctga gctgggcgta gcccccgatc atctgtgtcg gcttgacgtg aatccttgtc
      361 gggctgttat gggtgcctcc gcggttattt gtcagtttcg tgccgggcac gttgatgtgg
      421 cggtcctggg catggtgcat aaacgccatt cctttaggaa tccgatgaga caaaacggct
      481 ctcgcgacga ctacgccatt tcggttgaag cattcaatcc aatcgttgtc tttgatatcc
      541 gtatcctctg catcatcttt attcatccat acggtcggcc cgccgcggaa cagcgtcagc
      601 atcggcaggg aatcaaaata catgctgtgg acggaccatt tgttatgcgg cgtcaaataa
      661 ttaaggacga tttcttttcc ctcttgatca ggccgcttgc ttagaaacgg gcggtgctgg
      721 aggatcggtt taaatgtcgc catcgtttca ccgaattcca tcatcagttc atgatcgaca
      781 taataggatt gtctgcctgt cagtgtccgc cacgggatta atttttcaac attcgtcgta
      841 aacggcgaat acctgcggcc tcctttttca gagccggtaa atgccggaga cgtgataacc
      901 gttttcggct gggctgtaat ttgttcgaac gtaaagcatt cttcctcgcg ctcttccgcc
      961 aggtctttca gcttcaggtt tgtgatgttt tcaagtgatt cccatgcttt tacggcgacc
     1021 tttccattcg aagtggatga tagggttaaa accgcttctg ccgcctgctt tgcttcactt
     1081 atatttggac atccctttgc cacgctgtct gaggtgattt ctcccagtct ctttttgagt
     1141 gattcatatt catcggctat tgaccagctc atcccttttg ttccgctcgg ctttaaagca
     1201 gcgttaggac cgagtgcggt cattttatga aaaatgtgtt tgtaatcccg ttcaacgact
     1261 tggatgttcg gcatcgtttt tcccggaatg gcttcacatt cgcccttgct ccagtcattg
     1321 attttgccga atggctgggc caattcctgc atggtgtcgt ggaggagcgg cgtcgcaacc
     1381 acttctttca ccggctccat attgacttct tctgccagat cggaaacggc ttttgacagc
     1441 gccttgaaaa tatcccagtc tgacttcgat tcccacggag ctgagatcgc cggagcaaat
     1501 ggatgaatga acggatgcat atctgtgctg ctgagatcgt gtttttcata ccatgtcgcc
     1561 gccggcagca cgatatcgga atacagcgcc gtacccgcca ttcgaaaatc aagattgatt
     1621 aataagtcga gctttccttc cggcgcctgc tcccgccatt tgatttcttc agggcggatg
     1681 ctgtcgctgt cgtcattcat taaaccgttc gttgtcccca gcaaatgctt gagaaaatat
     1741 tcatgccctt ttcctgagct tgagatcaga tttgcccgcc atacaaagag attccttggg
     1801 aaattcactt cattgtcagg atcttcaatc gcgaatttca gttttttctc ttggagctgt
     1861 gaggccacgt acacacctac gtcttcaggt gttgctgccc ctgctttttc agcttcttta
     1921 tacagatcga tgccattttg attgaaagtc gggtaagacg gaagccaccc tagccgcgcc
     1981 gccagcacat tgtaatcagc gtggtgcttg tagcgggatg acgcagcaat cggtgatgcc
     2041 aaatcactga tcggctggtc ctcataacgc cactgatctg tcgcaaagta gaaaaatgaa
     2101 gtgccgtttt gcagcttggg cacgccctcc cagtcctttg cagttgcaat cgtctgccat
     2161 ccttcagcag gtcggagctt ttcctgcccg acgtaatggg cccagcctcc gccatttacg
     2221 ccttgggcgc ctacaagcaa aacaagattt aacactgctc ggtagatcgt gtcggagttg
     2281 aaccagtggt taatgccggc tcctacgata atcatagacc ggccgtctgt atcgatcgca
     2341 ttttgagcaa actctctggc aatcttaacg acagcttctt ttttgattcc tgtcatttgt
     2401 tcctgccagg caggcgtaaa cggctcagga tcatcatagg agacagcttg ttgttcgccg
     2461 atgccccgat ttacgccgta gttagccagt atcaagtcaa acacggtcgt gacgtacgtc
     2521 tcttcaccgt tcaggttcat ttttttaata ggaagatccc gctcgagcac tttgtttccg
     2581 tcatttgaaa aataaggaat gcgcaccgtg ccgatttcat cctctattcc gagcacagag
     2641 agacggggtt caatcggttc cccggtttct tcatcaatca tgtgcaggtt ccatttctgc
     2701 tgcccgtccc agcgcgagcc cattgtccct tggggtatgg caaatgaact tgtctgttca
     2761 tcccaaaccg caggcttcca ctgatcatgc tttgtcttcc gcccgatgtc cttcgcatgc
     2821 agaaaccgtc ccgctgtgta tacgccattt tcttttgaca gggtgacgag aaatggaaaa
     2881 tcagtgtatt gcttcgcgta ctcaataaaa cgttcagttt cttggttcac gtaaaattcc
     2941 tgcagaatga cgtgacccat cgccatcgca agcgccccgt cagtcccttg gcgaatactc
     3001 agccagtcat ccgcgaactt tgaggattcc gcaaaatccg gactgatcga aatgacctta
     3061 gcgcctttat agcgggcctc cgccaaaaaa tgcgcgtcag gcgttctcgt taacggaacg
     3121 ttggagcccc atgtgatgat atagccggaa ttgtaccaat cactgctttc cggaacgtcc
     3181 gtctggtcac cccaaatttg cggggatgcc ggaggaagat ccgcatacca gtcataaaaa
     3241 ctgagcatag ggcctccgat taacgacata aaccgggagc ctgatgcatg gctgatcatg
     3301 gacatggccg gaatcggaga aaaaccgacg tttctgtcag gcccgtattt catcactgta
     3361 tacagcagag aggctgaaat cagcttcagc agccattcag cgcgcacaaa accgcctttc
     3421 cctctcgcct gtttatagga cttcgctttt tcagggtttt cgacgatcga tttccaggct
     3481 tccaatggat tttgatgttc ttgcagtgcc tcccgccata aattaatcag tacaccgcgc
     3541 acgtatggat atttcacacg cagcgggctg tagatatacc atgaaaaact ggccccccgc
     3601 gggcagcctc tcggttcaaa atcaggcata tccgggcctg ttgatggata attcaaattt
     3661 tgcccttccc acgtgacaat tccgtttttc acataaatat tccagctgca agaccctgta
     3721 cagttaacgc cgtgggtgga gcgaacgact ttgtcgtact gccatctgtt tctgtataca
     3781 ttctcccaat cgcgatcgtc gcgggtggtt tggctatgtt tatttgaatg gtgttcgata
     3841 ggagagaaat aattcaatct cctaaacaac ggactccttt tctttttctt catgagagtt
     3901 cactccttcc gagtcaggtg atgctaagtt cactataaac agagacagcg tgtttccttg
     3961 tgaactatgt cacacactcc gcttttttca caaaatgttc acacaaagga gaaggaaggc
     4021 tgcgttcagg cagaacgctt gggtcattag ccgcctttca aagatcaaaa aaaccggctc
     4081 tatttaagaa ccgggctcgg cgttttcatc ctgtgatgta tgcagatacc gcaaaaataa
     4141 ttgataggaa caaaaaacat tttgctgaag catagccaaa aagttcattt gcagctgcgg
     4201 atgataagac atcattttct taaatatgta atatgggatg ttgagaatca gaatgtctga
     4261 agtggcattg actgagataa agggcgataa ataaagcccg cctttttcat caatcggaaa
     4321 cacatcgcct ttttcccaca gcgcaacggt tttcgaccct tcagggagcc ttgtgtccat
     4381 aaaacggaca ctgcctttta atacaatata aacagattga gaatgaagaa aagatggaga
     4441 ctgatcacac gaaccgcgga taaacgtgcc gtttttcagc aaggtttcga caatggatag
     4501 aggcacttca ttaaacatag gaagttgttt cagaaataat aaatagtcac actgattcat
     4561 aggaaaacct cctgtgctaa ggatagcttt agtgtagctc gactgagcct gtacagcagt
     4621 gatgtatttc acagcctgta tgatgaatgt cacttatcag gagggtgaat gcatttataa
     4681 tgaaagaaaa aaggaggatt tcgatgaagg cgctgattcc gaagcagcac ggggcgtggg
     4741 cgatgctgct gatcccattt ttactcggca tggtcaaggg aggccccgtt atttggcata
     4801 ttccgctctt ccttggttgg cttttcctat acttagcggt ttatcccgtt acgcttgcct
     4861 taaaaaagaa acaaagcaaa ccatatcaaa agtggatgtg ttattacggt tttcccgcct
     4921 gctgcttttt gatgatctcg gtctttcata agccgcctct catctgggtg ggcgtttctt
     4981 tactgccgct gtttctcata catatgtatt ttgcccgcag aaaaaacgaa cgagccttat
     5041 tgaatgatgt tgcaggtgtc ttgttctttt gttcgggcgg gtttgcgagc tgctggctgg
     5101 ggatgggaac ccttgacggc tgggcttggt ttattttctt gcagtctgct ttatttttta
     5161 tcgggagttc cttttatgtg aaatcggtga ttcgtgaaag aaaaaacagg acatttgcat
     5221 actggtcatg gggatatcac ctgctgctcc cctttttatc cgctcttttc ggagcaggat
     5281 ggtcgtttct cgcttttatc ccgagcagct tgcgggcatg gttttttcat ggaagggatt
     5341 ggcccgtaaa aacgattggc attctggaaa ttgtgaatgc ctgcttcttt cttgccgtca
     5401 tgtgcctgtt tatcacaagg taaaaaaaca aggacaccgc tgtccttgtt tttttcagtc
     5461 aatattgcaa atctccagcg ggcaattttc acactcaatc tcacatcgta aatagtcccg
     5521 cttgtgtaaa ataatttttc cggattcgtc tatcgaaata accccttttt tgcggagatc
     5581 tccgagcata cgattgacgc tttcacgtgc agccgcgcaa aactttgcca aatcctgatt
     5641 tgtcaggaca atgttaatca gaatgccgtc gcttcgctcc actccgtagc tgtttgataa
     5701 acggataagg gtggaataga gcgccccctt tttgccatga agaagcagat ccctgatttt
     5761 ggactgaatc ttccggaggt gcgtgctcat ccatttcatg aactcaaatg tcaaagcgcc
     5821 gttttggatt aattcttttt ccagcttatt tttattaatg acgagcacct cgccatcctc
     5881 tagcactttt gcactgagca tataccttgg ttcttcagtg aaaagtgtta attctccgac
     5941 gatatcatgc ttttggcaga ttctaagcgt caggtctttt ccatcagatg tcagcttgcc
     6001 gatttcaatg agtcctgatt gaatcagata aagctcttct gcatccattc cttcccgaaa
     6061 caaatacgtg tgtttttcca tttttctttt cgtgctgatc gattccagca attcatgcag
     6121 atcgctggat ataagatcac tatcagatgg tcgaacagag agaaaattca tgagctcacc
     6181 tcgaagaaag tcacgttgtg tgtttattgt aacgtgaatt gatttgtacc catcgagaaa
     6241 aaactaacaa tcttgtgaat gccccagtgt tagttgatgc tctggctgtt tctctccgtg
     6301 tgtgttttca ttctttcctg ccaatacatc catatgacaa ggacaaagct ggctaacgcc
     6361 acctctgaaa gcgccataaa cccgatcgcg tactggcctg ttgcctgaaa cacactcgcc
     6421 aatatgagcg gaggaaaaaa gccgcctaat ccgcccatgg cagacacaat cccattggca
     6481 atccccgctt gcttcgaaaa atagaaaggc accagtttaa aaacagtccc gtttcctatg
     6541 cctgagcaga cggccacagt taatgatcca aacgtataaa ggccgattgt cggcgagaac
     6601 gataggataa tgcctgataa tgtaagcccg gcaaaaacaa acatcaagat gcggagcggg
     6661 ctcattttat cagccaggaa tccgcccgca ggcctgagca gcgtagaaac cgcaataaag
     6721 ccagccgtcc gcaagccggc atctgcagga ttcagcccaa aatgctccac cagaaagttc
     6781 ggcagataga tagtgaaggc gacaaaggca ccgaacgtaa taaaataaaa caggctcaga
     6841 aaccatagca catgatttcg gtaaacggct ttgatttgag tcttaacaga aactttgacc
     6901 ttcttctcat gcctgtcgcc aaacaaaacg tgcagtaagg caaagacagc tagcaaaacc
     6961 aaatacatct gcacggttga tttccacccg acggcttgag cgataaccgg cgctgcaaat
     7021 gtcgtaacgg ctgtcccgat atttcctgca ccgtaaatcc cattgacgac accgtgcttt
     7081 tctttcggat aatatttcgg gagggaggtc accccaatgg aaaacaccgc tcccccgatc
     7141 cctaagaaaa agccgcctgc gattaaatca aacagagaat ccgcgatact gatccaaaat
     7201 acaggaaata aaagcaggat gaagctgacc ataaacatga gccgcgcgcc aaacctgttc
     7261 gttaaatacc ctaaaggaat gcggagaagc gacccgagga tcacaggaat tgccgtcacc
     7321 aaagaaatct cacccttgct taaatgaata tctaatgtga tttgggaaat gagtgatgaa
     7381 atcagcaccc aaaccataaa ccctgccacc aagcttaatg actgtaacga taattgaatg
     7441 tgttgacggt tgatcatttg gcttgcccct ttcaatgatt caataatcag tcttatcata
     7501 caaaaactcg gcaaacagga ttgtgaatta catcacacgt ttttctcata aaaaaaggac
     7561 aaagcccgaa gactttgtcc ttttgatcgt gattacattt tttccggagc cgatacgccg
     7621 atcagctgaa gcgcattgtt cagcgtaatt tgcgttgcct tcattaaagc caggcgcgcg
     7681 cggcttttct cttcattttc agggtcgatg actttctctg cgttgtagaa gctgtgcaga
     7741 gcagaagcca gatcataaat atagtttgtg acacggtgcg gaattcgttt ttccgctgct
     7801 tccgccactg cctctgggaa gccgccgatc gttttcagca gatcgtattc tttttctgat
     7861 tgaatatggc tgaaatcaag atctgccgcc ggtttaagtc cctgctcttc cccttggcga
     7921 agcatgctgc aaatacgggc atgcgcgtat tgtgcataat acacagggtt ttcgttagat
     7981 gttgatacag caagatctaa gtcaaaatcc atatgggtgt ccgcacttcg catcgcaaag
     8041 aagtaacgaa cggcatccaa gccgacttct tcaatcaggt cacgcatcgt tacggcttta
     8101 ccggtccgtt tgctcatttt cattttctcg ccgtttttgt aaagatgaac gagctgaatg
     8161 atttctactt caagcgttcc tttttcatag cccagcgctt caattgccgc tttcatacgc
     8221 gggatgtagc cgtggtgatc ggcgccccaa acgttgatca gcttatcaaa gccgcggtca
     8281 agcttgtcct tatgatacgc gatatcagga agaaggtacg tgtacgtgcc gtccttcttg
     8341 atcaatacgc ggtctttatc atcgccgaaa gtcgtggaac ggaaccaagt cgcgccgtct
     8401 tcttcataga catggccttt ttcgcggagc gcttcaagcg ccttgtcaat ttttccattt
     8461 tggtacagtg aagtttctga ataccacaca tcaaacggca cacggaagtt ttccaagtcc
     8521 ttgcgcagct tttccagctc gtatttcagg ccgtattcac ggaaaaactc gaggcgttca
     8581 ctttcctctt cgttaacgaa acgatcaccg tattcctcag cgagacgctt tccgatcgca
     8641 atgatatcct cgccgcggta gccatcctcc ggcatcggtt tttccaatcc gagtgcttca
     8701 aagtaacgga cttcaacaga aagcgccaga ttgttgattt ggtttcccgc atcgttaatg
     8761 tagtattcgc ggcttacatc gtaacccgct tttgaaagca cgttgcacaa ggaatcgccg
     8821 acagccgccc cgcgcgcatg cccgaggtga aggtctcccg tcggattcgc tgatacgaat
     8881 tctacctgaa ctcgttcacc gtttccgatg tttgtttccc cgtatgcttc ccccgcttcc
     8941 agtacagacg gaatcagctt tgttaaatat tgattgttca tatagaaatt gataaaaccc
     9001 gggccggcga tatccagttt ttcaatcgaa gcctttcctt tatcaaaatg agcgacaatc
     9061 tcttcagcga tttgacgcgg cgcttttttt gccactcttg ccaactgcat cgccatattc
     9121 gttgagtagt cgccgtgtgt tttatctttc ggtgtttcta aaacaacatt gggaatctgg
     9181 ctttcttcag ccagtcccgc tttcagaacg gccgctttga tttcttcttt cagcacgtcc
     9241 ttcatttgtt ccgcaatgtt catgcgtgag ttcctccctc atacgtgatc gtcatattat
     9301 gtaaatgctc ctgctcgtct ccgacatgca tgtcatatgc gatgctgata cggccttttt
     9361 cttcatcgag atcagattga atcgattttg tgcttgtttt cagctcaagc tcaccaaatg
     9421 acattttata tttagcaatt gtggaagctc ccgttacgaa acgctgattc attttgacag
     9481 cgcctgacct catgaccagg acttcgcctt cgcttacttt cacaatcgtt ttgactttgc
     9541 ctaagtcgtg ttcttcataa taagatagat acactttatt ttgttttaca tagtaaaatc
     9601 cggtggtgcg gaattcgatg acttcttggt ttccgtcatc ctcgatcaca gacttcacat
     9661 ggagtgttat cggtgtctct tgcttcattc tgacacgtcc ttttcatcat tccactttga
     9721 cttgaatagt ataatcattc ggtttgtaaa cttcaactgc ttctatctta ccatcattgc
     9781 tcatcagatt tgaagataaa cctcataaaa agcatttcct tatatagaag agaaaatcat
     9841 atcactaatt acctttagga aatgttacat ttttccgaaa tctatcattt ccttttcaca
     9901 tttttttcaa aatatatgca ttgaattagt aatttgatag ttttaagata aaagtacaac
     9961 atagatctgc tagaaaaaca aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacggctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgcttaaca tgctccagaa caagcaggtg atccagcttg
    10561 gaaaccgggc cagccgccat acaatcacca cgagcggcag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcacc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttga taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagcc tggagctttt gaagacttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcggg gcgaaggcat tttcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattgcccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattccc tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcag gcgccgcggt
    11461 tcagtgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc gaaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ctatctgttt acgctgattt tcattgccat tgccattctg ttcgggattc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggttgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 caggagaatt tcggagcttt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctgt ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtt ttttatcaga aaatgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tatgcggcta ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 cgaggtgatc ggccatgaat aacataatcc ccatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tgtttgaaat cgggctgatt cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatggt gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaact ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtatcag cgccgctttg atgccggccg ccacgcttcc gctttgcgcg gtgcatatgc
    13081 tgtgggcggt gatcattgac tttcctgtct ttctgcaggc gcctccgcag cagagcaaga
    13141 tgcattcatt tatgcggcga tctgaatttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggcgttcagc ggcttctttt
    13261 cgttccagat gatgaatacc ggcatcttca atcagcaagt ggtttatatc gtgatttccg
    13321 cgcttttgct catctgctcg ccgatcgccc ttttgtattc gattgaaaaa aatgaccgga
    13381 tgctgcttat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat gaaaaaaggc cctccttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 cattagccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatttcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacgattt atttttacgg cgccgccgca
    13921 tacctgaagg agcaaattat tgacgctttc ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgttgacgcc ctgctgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgagaatc
    14161 gaaaagaaat tcactgatcc tttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggaaag acaggataaa ggcgattcat
    14281 cctaaacggt ttctcgacgc aacggacttt atcgttgatt tagtgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccgaaagaat acccgtaaac cggcatgttt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa ggatctggca gtctatcacg ttatcacccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagat agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatgggga tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgtgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaagaga tggaaaataa agcctttttt caacaactgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcgcatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gatccccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaacgatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgctggacat cagtgattta caaaaagcct ataaggctgc
    15541 ctaccaaacc catcggatga cgctgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaagcg tccggattat catgctgaaa gaaaaatcat
    15661 cccggcatgc cctccagccc tctcacaaaa aatgatgctg ggtgatgagg agcggatgga
    15721 agatacatgg accggattac agatcggcgc acttcccggg caaaacgatc tgtgggtgat
    15781 aaagctttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cgttttttca
    15841 agagattcag caaacgtacc gtctggaaat cgatcgcttg tcagccgaga cttatatata
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggtt gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat gcgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcattcac gtttctcaga aagaggcgat cagacaatga aaaaaagcac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gatgggttca ggccgttgcc
    16321 gaagccgccg cccaatatgt acagatgatc aacaatgatg ctgttcggct cggactgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctat atcttcatta tgtcacccaa
    16441 tccgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 agctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcatcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcacac gccccctgcc
    16681 ctttcaatgg gacttgcgat gctactgatt ctgtatttat tgttttgcat gcgaacttat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agcgctggca
    16801 gcagccggga tttggtggat gctcagtttc tctataagtg aactgctgtt tctgattatc
    16861 ctggctacca ttcagcaaat cggatcattt atttataaac gattctctta tcgcagcacc
    16921 gcttctcttg atctataaaa tagctacatc gcaatcgcag acggacccgc gccaaccgga
    16981 atcaccgtca cggctgtata atcacttgtg cggtacacgg tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcga ggtcaaaagc gccggggaga
    17101 gacacgtttg caatgatcct ctgtctggcc gtattaacta catataagtt attaataaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtgc tatcgagaga aaatacaatc
    17221 gtcctcagcg tttcaaataa acggctgaag tcccctcccc tgcttaatgg agacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccattcaaca cgtacgcaaa atttccagcg
    17341 taaggagttg caattaaact gggaaattca aatgtatcta tgatactttc taccaactgc
    17401 ccagtattta tatcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcggaatgac atcaatgacc
    17521 gattgagagg ccgtgttaat cacatatata gatccggcgg ccatcacgta tgcgaactca
    17581 tcttttggat caaattcgat ctttctcggc cctcctccaa cagtaatggt atttatgatg
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat ttccatggag gacatacgtg
    17701 aatgctttat cgaaagtaac gcctagatta gttggcacgt cagaaaaagg gattgttttt
    17761 acaacagtgt ttaaatctgc atcaataacc gaaaccgtgc tgtctccagt attggcagta
    17821 aacacatacg attgagggtc tggtgatggc ggtaaaacaa gtgtcccggt caccgtaagc
    17881 ggactgccgt agaaaggcgg tacaatgagc agatcttcca ctgttatttg actgaaatca
    17941 ggacagcggc cagactgtgc tgcataataa acaacttgat caatctcttc ggtatgaatc
    18001 acagaaaccg ccccattgcc ttgtccatat tgatttcgca caggcgacac actgacaaga
    18061 agcgtaatgg tcccttgtac tctcacagca tatcgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacacat tgtctgtact ccatgtaaca
    18181 gccgctgacg cttcggccga atcaaccttg aagccctcag ggatatctat cggcacttga
    18241 aacggcgctt ctcggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaagca
    18301 gaaagatcat tctttttcat gatttcacgt ccttttagaa atgcacaaca tgcagcggtt
    18361 aaatcgtaat ggcacccggt gaaaccccaa gagatatcac agtttcctca gaataatcat
    18421 ctgtgttgta aacaatgatg ctctgctcta taaaacgagt tgcatacaga aaatcgccat
    18481 tcggggtaaa cgcatagtct gttgctgatt gcggaagatt tccaattaca cctgctccat
    18541 tcggactgac agaatataaa ttgccagtga agctgtcatg taaatacacc tctgatccac
    18601 tcgtaaacat tacatatagc ccgtcaggct ccagctcttg ggtatccctg atcgtaaacg
    18661 tatttaaatc aataaccgtc aaataattga ataagaattc ttgttctaat acatacgcat
    18721 accgctccgt agaatctgtt tctatggatg atacgataag ctctcgttca atcgttccta
    18781 agacttcacc ggtagataag tccacttttt gcactaaccc aaaattaaga acataggcga
    18841 acaacccatt ggggtcaatt gcaatatcaa aaccttctac aggaatagac ctctcaacag
    18901 tcaacgtatc aattccaatc acataaatgg cagtaccggt gaaaacataa gcaaactcat
    18961 gattagggat aaatctaatc aatcgaggcg gctgatccag caatatagtt gctgtcactg
    19021 ttaatgtgtc ataatcgatg acagaaatca cattattgtt gggatgtaag acaaacacag
    19081 cgcttttatc tggcgtaatt tcaatacctg ccggattgta cggaagagca atcgttgtca
    19141 caacagtatg ggtgtttgta tcaatcacag aaactgattg atcatttgga ttcgctgtaa
    19201 acgcgtagac gggttccggc tccggtacaa gcacaatcgt ccccgtcacc gataaaggac
    19261 tgccgtaaaa cggcggaaca acaacaaggt tctcaatcgt gatgtcactg atatccgggc
    19321 aatcatccgg ttcatcggaa taatagacga cttgatcgat ttctgcattg tgaatgacgg
    19381 aaacagcccc gtccccttgt ccatattgat ttcgcacagg tgagacactg acgagtagcg
    19441 taacggttcc ctgcaggcgc actgcaaatt gaacaccgac ctcatcaggc tctggccccg
    19501 tttgaattaa gcaacggtca ctgacacaag aaaggctgtc tgcattccac gtcacgtttg
    19561 caacagcttc agccggatca acgacaaatc cttcaggtaa ttcaatcggc gcttgaaaca
    19621 tggcttctcg gcttgcttct tcctcacaaa aacataagca ctcttcttgt tctgctcctg
    19681 cttttacttt aaaggaaagc ttgttttttc tcattccttc acttcctttt cagacataca
    19741 ctgctcacgc agatataaca gaatatggaa gggtaacgtg tttgcttgta caaattgctg
    19801 agggtaaaag cttctttttg aaaatatatc tccaaacatg cggtgtaacg aaagaaaaaa
    19861 ttgcggtttt tttgcgcttc tcacaagaat gttgatgata aaatatgaca tatatagaat
    19921 taagaaggga gggatttgca aacgtgacag gtgtcatatc ttcttcttcc atcggagaaa
    19981 agattaacga atggtatatg tacatacgcc gattcagcat acccgatgca gaatatttgc
    20041 gacgagaaat caagcaagag ctggatcaaa tggaagaaga ccaagacctt catttgtact
    20101 attcactgat ggagtttcgg cacaacctga tgcttgagta ccttgaaccg ttagaaaaaa
    20161 tgaggattga ggaacagccg agactgtctg atctgctgct tgagattgat aaaaaacagg
    20221 ctcgtttaac tggtctgctt gagtactatt ttaatttctt cagaggcatg tatgagctgg
    20281 atcgccgtga atatgtatta gccattcaat tctttaaaaa agctgagagc aagctggttt
    20341 ttgtcaaaga taaaatcgat aaagctgaat tctttttcaa aatgtcagaa gtctattatt
    20401 atatgaaaca aacttatgtc tccatggact atgcacgtca agcattcgaa atatacagtg
    20461 aacagactac atatgatatc agaatgattc aatgccagtc cttattcgga gccaactttt
    20521 tggatttaaa acaatacgaa aaagcaattg cccattttca aaaagccttt acacttgcaa
    20581 aaacagagca gcagccccaa ttaatgggaa gaacacttta taacatagca ctctgcaagc
    20641 aaaaccaaaa cagttttgaa tcagcgatag agtatgtaaa aaaatctatt caagtatttg
    20701 aaggatctaa aatgcttcct tcattgccac aagctttttt cctaattaca caaatttatt
    20761 ttaaattagg taagattgat aacgcctgtg aatatcataa aaaaggaaaa gagtattctg
    20821 cagctgcggg agataccgtg tatctaacgg agtttgaatt tttggaatct ttatacttgt
    20881 ctggaccgga tgaggaacgg atagaaaaat gttttgtttt tcttgaaagt aaaatgatgt
    20941 atgcagatat tgaggacttc gcacttgatg ttgctaaata ttatcatcaa caggaaaatt
    21001 acaaaaaagc atctcattac tttttaaagg ttgaagaagc aagacagcac attcaagggg
    21061 gggtgaattt atatgaaatg gaagtataaa ttattactcg cttgtttagc tgtgagtgct
    21121 gtatttatca cagtcgaagt atcaaattca tcaacagaac attttgatgt tgcgcaacgc
    21181 gccatgatct aaaccgccgt ccatcggcgg tttttttgtc ccctctttac ccagtctccc
    21241 aatccatgct atgatttttt caataatctt aaaaatagtg gaaatgcagc atgtctctaa
    21301 aaagtgtgag aacccacttt acacagtgga atcgagaaaa tgatgtgacg gagttcgaaa
    21361 cgtcgagcgc gacagtgttg aacagacagc tgagacgatc ggcgtaagcc cgactagaat
    21421 cgccaagacc ctgtccttca gaggggaagg agatcaggcg attctgattg tggcagccgg
    21481 cgatgccaag attaataaca aaaagttcag gcaaacattt ggctttaaag caagagtgct
    21541 ctctcctaat gaggtactgg agcagacagg ccatgaaatt ggaggtgttt gcccatttgg
    21601 gttggctcat ga
//
