LOCUS       NZ_CP093291            25238 bp    DNA     circular CON 24-MAR-2024
DEFINITION  Bacillus mycoides strain DSM 2048 chromosome, complete genome.
ACCESSION   NZ_CP093291
VERSION     NZ_CP093291.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5285600)
  AUTHORS   Chiba,A., Peine,M., Kublik,S., Baum,C., Schloter,M. and Schulz,S.
  TITLE     Complete genome sequence of Bacillus mycoides, isolated from an
            agricultural field in Rostock, Germany
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5285600)
  AUTHORS   Chiba,A., Peine,M., Kublik,S., Baum,C., Schloter,M. and Schulz,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2022) Research Unit Comparative Microbiome
            Analysis, Helmholtz Zentrum Muenchen, Ingolstaedter Landstr.1,
            Neuherberg 85764, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2021
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1166.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022630575.1-RS_2024_03_24
            Annotation Date                   :: 03/24/2024 09:23:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,704
            CDSs (total)                      :: 5,549
            Genes (coding)                    :: 5,305
            CDSs (with protein)               :: 5,305
            Genes (RNA)                       :: 155
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 108
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 244
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 93 of 244
            Pseudo Genes (incomplete)         :: 175 of 244
            Pseudo Genes (internal stop)      :: 63 of 244
            Pseudo Genes (multiple problems)  :: 79 of 244
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4246095
            Orig. end                         :: 4271333
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP093291.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Research Unit Comparative
            Microbiome Analysis, German Research Center for Environmental
            Health, Ingolstaedter Landstr. 1 85764 Neuherberg.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25238
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="8"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..25238
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25238
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15238](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15238
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            458..1300
                     /locus_tag="MN093_RS22045"
                     /old_locus_tag="MN093_22045"
     CDS             458..1300
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002141840.1"
                     /locus_tag="MN093_RS22045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22045"
                     /product="metallophosphoesterase"
                     /protein_id="WP_241875565.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.3e-09, bitscore:
                     36.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNINRVILIVSTIVGIIIFSYLQNNLISVNEVNIASSKIPSSF
                     KGFKILQLSDLHNKKFGENQNVLIKKVKNLNPDIIVITGDLIDSKSYNAEISLQVIREL
                     VTEYPVYFVTGNHEQWSGKYNSLEKELKKYHVTVLRNEHVSIQKEGQEINLLGIDDPEF
                     TSGNRDEEHIVKNEIRKAKDGMNSDGFKILLSHRPEFLEAYADEQVDLVLSGHAHGGQV
                     RLPFIGGLVAPNQGILPKYTVGLYEQQNTSMIVSRGLGNSIIPQRVFNRPEIVVVQLN"
     gene            1517..1768
                     /locus_tag="MN093_RS22050"
                     /old_locus_tag="MN093_22050"
     CDS             1517..1768
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548597.1"
                     /locus_tag="MN093_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22050"
                     /product="hypothetical protein"
                     /protein_id="WP_002017002.1"
                     /transl_table=11
                     /translation="MHKEFEIEEYTAIEEQIHYYSTSLLVSHPEQIVKYLEKRLEKYAE
                     TLQYAHLYPETVILPIQQIVIEYSLDVARIRRYLNLKT"
     gene            1952..2677
                     /locus_tag="MN093_RS22055"
                     /old_locus_tag="MN093_22055"
     CDS             1952..2677
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129461.1"
                     /locus_tag="MN093_RS22055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22055"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_131246210.1"
                     /transl_table=11
                     /translation="MKQPSIILRDVSKSFGKKEVLHNLSLQVEKAEIFGLVGPSGSGKT
                     TLIKMIAGINESTTGDVIVFNTNMPNLNEMKRIGYMAQADALYEELSAYENADFIATMY
                     GLKGKRKKERIVEVFELVQLSEHMKKQVQHFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKSIWEKFYDLKKKGTTIIVTTHIMDEAEFCERLGLIREGNLVAIGTPEELKK
                     QTSSGRIEDVFMLEGVIES"
     gene            2674..3693
                     /locus_tag="MN093_RS22060"
                     /old_locus_tag="MN093_22060"
     CDS             2674..3693
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161721.1"
                     /locus_tag="MN093_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22060"
                     /product="ABC transporter permease"
                     /protein_id="WP_033709125.1"
                     /transl_table=11
                     /translation="MRVNGVVIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLIFTQKDYI
                     PHIAVVDVPAPIVKAMKNQEASIYEYSKDKAISELEKQKVDAVIHLENGKMNLLLEGSD
                     SSKNRAVLQVLQKSTEKNNVSMMKPEVDYLHGSKDITMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPVRRWEIVLGYIIGFGIFAFIQSIIIVSFSVYILDLYVAG
                     SIWLTLLITCMLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQVFFSGLFPMESMNTW
                     LQMLGKLFPLTYGADAMRQVMIRNQGFTEIALDLTVLLLFSLLFAVGNVFALKKHRKI"
     gene            3718..4377
                     /locus_tag="MN093_RS22065"
                     /old_locus_tag="MN093_22065"
     CDS             3718..4377
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161720.1"
                     /locus_tag="MN093_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22065"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_131246211.1"
                     /transl_table=11
                     /translation="MKKDWLEELVAATNTDKRNERQMRILEAAVDMFGEKGYASTSTSE
                     IAKRAGVAEGTIFRYYKTKKDLLFAVVMPTLTKFAAPFFIQAFAKEIFKKDYKSYEGLL
                     RVVIHNRFEFAKKHFPMIKILIQEVPFQPELKSEIQQLVETELLSHFKKLIVKFQEEGE
                     IIEMPPSSVLRLTLSAVLGFLLTRFLLLPEEKWDDEVEIENTIQFILYGLTPRTSL"
     gene            complement(4601..4900)
                     /locus_tag="MN093_RS22070"
                     /old_locus_tag="MN093_22070"
     CDS             complement(4601..4900)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728146.1"
                     /locus_tag="MN093_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22070"
                     /product="WGxxGxxG family protein"
                     /protein_id="WP_131246212.1"
                     /transl_table=11
                     /translation="MKKKLSSILSVLALSIMFLGTSAQAEYDGNHMNRVNNTDMSTRVN
                     DNNMNRVNNDVRTRNVNTTNDLNDNRDKNNNWAWLGLLGLAGLLGLRRRDKETR"
     gene            complement(5073..5588)
                     /locus_tag="MN093_RS22075"
                     /old_locus_tag="MN093_22075"
     CDS             complement(5073..5588)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512145.1"
                     /locus_tag="MN093_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22075"
                     /product="DUF3231 family protein"
                     /protein_id="WP_000538613.1"
                     /transl_table=11
                     /translation="MGVLSGNPQNEPMHYGEVFAIWSYLAGAQGAIAGYQVLVNHTGDE
                     DLKKFLENLIENDIQSEVEELKNLLKSNGVALPPAPPERPVASIETIPPGARINDAEIA
                     AKVSMDLAAGLVACSQAMGQSLREDVGMMFGQFHMKKAQAGATLLRLNKKKGWIIPPPL
                     HVLQSDQA"
     misc_feature    complement(5867..5882)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.99"
                     /tool="antismash"
     misc_feature    5954..5967
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.68"
                     /tool="antismash"
     gene            6054..7022
                     /locus_tag="MN093_RS22080"
                     /old_locus_tag="MN093_22080"
     CDS             6054..7022
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248633.1"
                     /locus_tag="MN093_RS22080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22080"
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_131246213.1"
                     /transl_table=11
                     /translation="MRQFAKPTIVVSKCLEFDACRYNGEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGTPRETIRIVEKNGANRLVQPSIREDVTEKMNEFSNAFLQTLPEVDGFILKN
                     RSPSCGTRDVKIYSSFEKGPVKGKGTGLFGGAVIKKFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAHYKMIKHTKNIKELVAFQSDYKYLFMAYNQVKQKELGRIIANQKNETIEVVFD
                     NYEKTLYELFMRAPRYTSNVNVCEHIFGYFKTKLKKQEKDHFLELIQKYAEKKIPLSSL
                     LTILKSWAIRFDEKYLLRQTYFEPYPEGLVEISDSGKGRDY"
     gene            7239..8384
                     /locus_tag="MN093_RS22085"
                     /old_locus_tag="MN093_22085"
     CDS             7239..8384
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001980414.1"
                     /locus_tag="MN093_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22085"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_002032227.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 5.3e-39, bitscore:
                     131.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.8e-26, bitscore:
                     89.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.8e-57, bitscore:
                     192.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTAEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTLSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKFLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAILDGDEYVISGEKCWITNAEYA
                     NTIIVTAINGFEDNGKKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKPISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANHAVQIHG
                     GYGYMREYEVERYIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     gene            8400..9737
                     /locus_tag="MN093_RS22090"
                     /old_locus_tag="MN093_22090"
     CDS             8400..9737
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486723.1"
                     /locus_tag="MN093_RS22090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22090"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_044440840.1"
                     /sec_met_domain="ATP-grasp_3 (E-value: 2.6e-06, bitscore:
                     25.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.7e-10,
                     bitscore: 38.4, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 2.6e-06, bitscore: 25.5,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4e-09, bitscore: 34.6,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKLA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNAEAIHPGYGLLSENPSFPIRCKEEGIVFIG
                     PSEEIITKMGSKIESRIAMQEADVPVVPGITTNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLVDDQ
                     KNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIAYGEKLSFTQDDVKRSGHAIEARIY
                     AEDPKTFFPSPGKITDLTLPTNIRIDHFLENQVTITPFYDPMIAKVIAHGETREEAISK
                     LKIALEELKVEGIKTNTPMLLQVLGDDVFKSGIYTTGFVTKQLVKK"
     misc_feature    8443..8457
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            9764..9979
                     /locus_tag="MN093_RS22095"
                     /old_locus_tag="MN093_22095"
     CDS             9764..9979
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001987345.1"
                     /locus_tag="MN093_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22095"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_001985297.1"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIVSE
                     EAGTVMKINVQEGDFVNEGDVLLEIE"
     gene            10001..10912
                     /gene="mvaB"
                     /locus_tag="MN093_RS22100"
                     /old_locus_tag="MN093_22100"
     CDS             10001..10912
                     /EC_number="4.1.3.4"
                     /codon_start=1
                     /gene="mvaB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017149491.1"
                     /locus_tag="MN093_RS22100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22100"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_131246214.1"
                     /sec_met_domain="HMGL-like (E-value: 3.7e-48, bitscore:
                     162.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADASDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALAVIEDITKQAMFEGKKVRGYVSTVFGCPYEGDISATAVDEIC
                     NQLFSYGIYEVSLGDTIGVANPLQVEQVLEHLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEYGITTFDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLLRASHFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     gene            10917..11705
                     /locus_tag="MN093_RS22105"
                     /old_locus_tag="MN093_22105"
     CDS             10917..11705
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 5.6e-75. Score:
                     243.7. Matches aSDomain:
                     nrpspksdomains_MN093_RS22105_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001990763.1"
                     /locus_tag="MN093_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22105"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_215577102.1"
                     /transl_table=11
                     /translation="MLQLQNISVDYVTPHVVKISLNRERQANSLSLALLEELQTILTQI
                     NEESNTRVVILTGDGEKAFCAGADLKERVNMSEEQVRHAVGMIRSTMEMVEQLPQPVIA
                     AINGIALGGGTELSLACDFRIASDTASLGLTETSLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISAQEAKEYGLVEFVVPADLLEEKAIEIADRIAKNGPIAVRLAKEAISNGIQV
                     DLHTGLQMEKQAYEGVIHTKDRLEGLQAFKEKRKPMYKGE"
     aSDomain        10959..11678
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MN093_RS22105_ECH.1"
                     /evalue="5.60E-75"
                     /label="MN093_RS22105_ECH.1"
                     /locus_tag="MN093_RS22105"
                     /protein_end="254"
                     /protein_start="14"
                     /score="243.7"
                     /tool="antismash"
                     /translation="HVVKISLNRERQANSLSLALLEELQTILTQINEESNTRVVILTGD
                     GEKAFCAGADLKERVNMSEEQVRHAVGMIRSTMEMVEQLPQPVIAAINGIALGGGTELS
                     LACDFRIASDTASLGLTETSLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE
                     YGLVEFVVPADLLEEKAIEIADRIAKNGPIAVRLAKEAISNGIQVDLHTGLQMEKQAYE
                     GVIHTKDRLEGLQAFKEK"
     gene            11708..13249
                     /locus_tag="MN093_RS22110"
                     /old_locus_tag="MN093_22110"
     CDS             11708..13249
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012094296.1"
                     /locus_tag="MN093_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22110"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_107888194.1"
                     /transl_table=11
                     /translation="MLDQKQQSNSFEERVETIKQGGATKYHEQNKAKGKLFVRDRLALL
                     FDNGEYVEDALFANCEQTGLPADGVVTATGKIHGRTACVMANDSTVKAGSWGARTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQICLLF
                     GPSAAGGAYIPAFCDVVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPSNYLEKTPLITPQEPKQFDKTLEEIIPENQNAPFNM
                     KDLINRIIDEGSFFEVKKLFAQELITGLARIDGKPIGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIVVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERASFIAEKR
                     EEYKKDIDIYRLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     gene            13298..15238
                     /locus_tag="MN093_RS22115"
                     /old_locus_tag="MN093_22115"
     CDS             13298..15238
                     /NRPS_PKS="Domain: AMP-binding (95-521). E-value: 2.4e-82.
                     Score: 268.6. Matches aSDomain:
                     nrpspksdomains_MN093_RS22115_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017560287.1"
                     /locus_tag="MN093_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22115"
                     /product="AMP-binding protein"
                     /protein_id="WP_044440829.1"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-87, bitscore:
                     291.1, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQAVWFPTEEYKEKTRLFGWMKSLGYEDYEAFYNKSIEETAWFW
                     GEAERAVGYQWMKPYTEVLDLENGTPFAQWYTEGTCNVVESALSRWLADDKTKTQAALM
                     YEGENGTSKSFTYEELDSWVSRVANGLKHAGIEKGDRVTIYMPMIPETVVAMLAVMKIG
                     AIISPIFSGFAADAVMTRVQAAGSKMVITADGFSRRGKIVSLKDEVDKACEHCPTVEKV
                     VIVRHAGNDFTPHNYDFSWSTLEKEKPFIHAEEMNSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKSAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPE
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFNTVGKGKVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGKPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVIYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHNEVIEAAAVGVPDDVKGEVCHCFVVLRDGVTFSGELKK
                     ELMSLVNSHIGKALCPKDIHVVEDLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PFIQGLQSSKL"
     aSDomain        13583..14860
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MN093_RS22115_AMP-binding.1"
                     /evalue="2.40E-82"
                     /label="MN093_RS22115_AMP-binding.1"
                     /locus_tag="MN093_RS22115"
                     /protein_end="521"
                     /protein_start="95"
                     /score="268.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="KTKTQAALMYEGENGTSKSFTYEELDSWVSRVANGLKHAGIEKGD
                     RVTIYMPMIPETVVAMLAVMKIGAIISPIFSGFAADAVMTRVQAAGSKMVITADGFSRR
                     GKIVSLKDEVDKACEHCPTVEKVVIVRHAGNDFTPHNYDFSWSTLEKEKPFIHAEEMNS
                     DDPLMLIYTSGTTGKPKGTVHTHAGFPLKSAFDAGFGMNIKQGDRVLWVTDMGWMMGPF
                     LLFGSLINGATMVMYEGVPDFPEADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNK
                     HSLKSLEVFASTGEPWNPDPWMWLFNTVGKGKVPICNYSGGTEISGGIFGNVLIKPIAP
                     ISFNASLPGMAAVVLDDQGKPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFEN
                     KWVHGDWVIYDGEQYIITGRSDDTLNI"
     CDS_motif       14084..14140
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MN093_RS22115_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="MN093_RS22115"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     CDS_motif       14831..14893
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MN093_RS22115_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="MN093_RS22115"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     gene            complement(15682..15879)
                     /locus_tag="MN093_RS22120"
                     /old_locus_tag="MN093_22120"
     CDS             complement(15682..15879)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002017016.1"
                     /locus_tag="MN093_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22120"
                     /product="hypothetical protein"
                     /protein_id="WP_002017016.1"
                     /transl_table=11
                     /translation="MDKKDLLSQQLDPVSLDALNTPSKAQEQLQETSQEAHNSNKKDST
                     QALHGEDLPISDVYRTTNKQ"
     gene            16197..16412
                     /locus_tag="MN093_RS22125"
                     /old_locus_tag="MN093_22125"
     CDS             16197..16412
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237376.1"
                     /locus_tag="MN093_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22125"
                     /product="hypothetical protein"
                     /protein_id="WP_060751685.1"
                     /transl_table=11
                     /translation="MVIVTLAIVPGESRSEAVTVTVPDPLAARNKAVKLPKELVMTARG
                     TMKAREGLLNEKLTTTPGVGLPFTNT"
     misc_feature    16432..16449
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.05"
                     /tool="antismash"
     gene            16458..16643
                     /locus_tag="MN093_RS28450"
     CDS             16458..16643
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254006.1"
                     /locus_tag="MN093_RS28450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_277883513.1"
                     /transl_table=11
                     /translation="MVSLEVKVIDAGPAGRLNPVGPVEPVEPVDPFDPFDPVEPVGPIN
                     PVEPVAPVEPVGPVGN"
     gene            complement(<16661..16717)
                     /locus_tag="MN093_RS28550"
                     /pseudo=""
     CDS             complement(<16661..16717)
                     /GO_component="GO:0043592 - exosporium [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03720.3"
                     /locus_tag="MN093_RS28550"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="exosporium leader peptide-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDEFLSFAALNPGSIGPTL"
     gene            complement(16915..17283)
                     /locus_tag="MN093_RS22135"
                     /old_locus_tag="MN093_22135"
     CDS             complement(16915..17283)
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002189674.1"
                     /locus_tag="MN093_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22135"
                     /product="septum formation initiator family protein"
                     /protein_id="WP_088034841.1"
                     /transl_table=11
                     /translation="MGNIPKISSQQSNPKIPSQQVNANTKLGNNKKTRRRIITTLAFIL
                     PIIFVLQYSLNNQQEMIKEKQITVNTEQQKLSTLKKDGHTLKNDVKVLTGSEEEVLKFA
                     RKLYGFSKPNETIFQITE"
     gene            17613..17783
                     /locus_tag="MN093_RS22140"
                     /old_locus_tag="MN093_22140"
     CDS             17613..17783
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284255.1"
                     /locus_tag="MN093_RS22140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22140"
                     /product="hypothetical protein"
                     /protein_id="WP_215577104.1"
                     /transl_table=11
                     /translation="MYQGDHFITEGTILEVSEKANKSLYWRWCMLAPSYEKVCGNSTKR
                     LRLIRIDDDDE"
     misc_feature    17827..17840
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.54"
                     /tool="antismash"
     misc_feature    complement(17828..17841)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.54"
                     /tool="antismash"
     gene            17950..18330
                     /locus_tag="MN093_RS22145"
                     /old_locus_tag="MN093_22145"
     CDS             17950..18330
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450238.1"
                     /locus_tag="MN093_RS22145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22145"
                     /product="hypothetical protein"
                     /protein_id="WP_002127497.1"
                     /transl_table=11
                     /translation="METSTFLGLFWGWITVIVSGILFVRPSVLRELKKLVVEDRGFGIM
                     YGFLSIFLGLGSVILHNVWVFNWQGFLTVIAWLALLKGIYIIAYPEPSKKTDFELRVLS
                     TRIALAIIGALALWMLIVIYIK"
     gene            complement(18438..18740)
                     /locus_tag="MN093_RS22150"
                     /old_locus_tag="MN093_22150"
     CDS             complement(18438..18740)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MN093_RS22150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MN093_22150"
                     /product="hypothetical protein"
                     /protein_id="WP_215577105.1"
                     /transl_table=11
                     /translation="MKGGIKECPGKMIAGVLRKSIVVMTGGNLKKRIIVMMIGVLRKSI
                     VMMIGGNLKKRIIVMMIGVLNEISVVVNVSLFVVIVKEKIGNVFNIDLKERTCLL"
     misc_feature    complement(18901..18910)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            19202..19558
                     /locus_tag="MN093_RS22155"
                     /old_locus_tag="MN093_22155"
     CDS             19202..19558
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002032241.1"
                     /locus_tag="MN093_RS22155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22155"
                     /product="hypothetical protein"
                     /protein_id="WP_002032241.1"
                     /transl_table=11
                     /translation="MGSRFNNCRKKCTCKHDDCWDIFEECKKEKNEKCDSSCVQGIRDE
                     LKKLINKTVRINTEGRTYIGTVSSVTCDVVKLAAIPGSVAAIISLCKIEAILPPATTVT
                     DEFDFNGVDVANKD"
     gene            19683..20195
                     /locus_tag="MN093_RS22160"
                     /old_locus_tag="MN093_22160"
     CDS             19683..20195
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002127499.1"
                     /locus_tag="MN093_RS22160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22160"
                     /product="GNAT family protein"
                     /protein_id="WP_215577106.1"
                     /transl_table=11
                     /translation="MIKLKQFTRSDFKQLINWINSEEFLIQWSGNAFTYPLNEQQLEKY
                     TESANTLAFKIMDEETKAVIGHISLGQIDNINKSARIGKVLVGNTKMRGRSIGKHMMKA
                     VLRIAFDELKLHRVTLGVYDFNKSAISCYEKIGFVKEGLLRESKRVGETYWNLWEMSML
                     EYEWNNK"
     gene            20262..20804
                     /locus_tag="MN093_RS22165"
                     /old_locus_tag="MN093_22165"
     CDS             20262..20804
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002176841.1"
                     /locus_tag="MN093_RS22165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22165"
                     /product="hypothetical protein"
                     /protein_id="WP_215577145.1"
                     /transl_table=11
                     /translation="MISIAAVSGGGKTTITESLAHELKNSKALYFDRYKFDNCSVDICK
                     WIDDGANYDEWVLTPLMNDIQRSIQDSSLDYIIVDYPFAYLNREVGQFIDVTIFIDTPL
                     DIAMARRILRDFKEDTMSEIHNNLKHYMTQARKAYLEAIHTVKPHSDIVLDGSLSISEI
                     IDQIIEELNRREVIVNG"
     gene            <20825..21058
                     /locus_tag="MN093_RS22170"
                     /old_locus_tag="MN093_22170"
                     /pseudo=""
     CDS             <20825..21058
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288270.1"
                     /locus_tag="MN093_RS22170"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22170"
                     /product="DinB family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="KSLSDLYRRELDNFLQLWSGDFESKILKASWTDKSYKYGEVLRHV
                     IVHEIHHIGQISIWARELNLQPVSANLIGRGL"
     gene            complement(21117..22133)
                     /locus_tag="MN093_RS22175"
                     /old_locus_tag="MN093_22175"
     CDS             complement(21117..22133)
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160038.1"
                     /locus_tag="MN093_RS22175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22175"
                     /product="serine hydrolase"
                     /protein_id="WP_002136457.1"
                     /transl_table=11
                     /translation="MQFLKKITVLLLSFLITALIVLYFYLYVNGPIIQAKSATLIDTNS
                     GEIVYKKNEETPIQSATLSKLMTEYIALEQLNEGKIQLDELVKISNEVFRAETSPIQVT
                     SKDKTTVRDLLHALFLTGNNRSALALAEHIAGNEDNFTLLMNDKAKQLKLSQPSPFLNA
                     TGINNDTNKQSTTTSIDVAKLATQLVKDFPDVLNVTKLTSYQFTFKDSKVFNTNKMIYS
                     LNKNIKLQGVDGLQTSFSTNGNYSFVSTATRGDTRLISVILDAGDENSTFIETKKLLQY
                     GFDPSSYSALQAFKDAVTSWTILFQFKNLIIQTIMIFFIITILMFLYIRQKKAEDFN"
     gene            complement(22315..23472)
                     /locus_tag="MN093_RS22180"
                     /old_locus_tag="MN093_22180"
     CDS             complement(22315..23472)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016127015.1"
                     /locus_tag="MN093_RS22180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22180"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_002085430.1"
                     /transl_table=11
                     /translation="MRNEAFDILKDIPKWKLIFWLLLAITLTPITELIIFRLVTSVIES
                     SLTLSELGKEFIRIFGHEKYIGLKESLWMMIVSYLFLFSIFSSYLYIFYRHERKVYYET
                     CIKKMIEEIRYIASGNFNHKVSIVHHNYLEELATGVNQIIEQLKVSIDEERQAEQAKSE
                     LITNVSHDLRTPLTSIVGYVNLIHHDNYRDEVELRYYIQVIYDKVTRLNALMNDLFEYT
                     RVQNKELSLYSAPIDIVELLGQLTVQFRIQLQEANIECRPSFPSQKLMVLADGDKLVRV
                     FENLIINAITYGNDGDHIDITAYESNNMITIDITNYGQPIPSTDLPHIFERFYRVEKSR
                     STNTGGSGLGLAIAKSIVELHKGTIEVYSDDKKTTFTVKLLPYKA"
     gene            complement(23462..24157)
                     /locus_tag="MN093_RS22185"
                     /old_locus_tag="MN093_22185"
     CDS             complement(23462..24157)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038809.1"
                     /locus_tag="MN093_RS22185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22185"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002016575.1"
                     /transl_table=11
                     /translation="MNKNILIIDDDKDIVELLAVYLRNEGYNIYKAYDGDEALQMICTY
                     EVDLMLLDIMMPKRNGLEVCQEVRENNTVPILMLSAKAEDMDKILGLMTGADDYMIKPF
                     NPLELVARVKALLRRSSFQNATSQKNEDGIIRIRSVEIHKHNHTVKVNGEYIKLTSIEF
                     DILYLLASNTGRVFSSEEIFERVWNEDGYGSNKTVMVHISNLRDKLETVMNGEKLIHTV
                     WGVGYKIEK"
     gene            24355..24963
                     /gene="yqeK"
                     /locus_tag="MN093_RS22190"
                     /old_locus_tag="MN093_22190"
     CDS             24355..24963
                     /EC_number="3.6.1.41"
                     /codon_start=1
                     /gene="yqeK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000965880.1"
                     /locus_tag="MN093_RS22190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_22190"
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="WP_215577107.1"
                     /transl_table=11
                     /translation="MLYNDIYSFTPTGKIENDIKAFLLKYNKEFTYKHSIRVANEARKI
                     AKIFYEDEEKAAIAGCLHDISAIFPNEERITVAEKFGIEILQEEREFPMIIHQKLSRVI
                     AKEVFKVEDKEVLNAICCHTTLRKHATKMDLVLFIADKLEWDQIGTPPYLINVKKALGN
                     SLEHAAFVYISYLWERKDTLKVIHPWLEEAYWYLKEIVE"
     misc_feature    25019..25034
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 19.79"
                     /tool="antismash"
ORIGIN
        1 actgactggg tagttggaga taaatcagga gctggaagtt atgggacacg aaatgatatt
       61 gctatcgttt ggccgccgaa cagggcacct attatcattg caatcttatc tagtaaagat
      121 gagaaagaag ctacctatga taataaatta attgcagatg cagctgaagt tgtaatcaat
      181 gctcttaagt gataatcttt cagttttttc atttctttat ataatattat taaaagtata
      241 aaattagaaa acgattcttt ttcgtgtgaa aagaatcgtt ttttttgtat tcttataatt
      301 caaagggtaa aagtaagaat ataatgaaaa tacattacgt atccggaatg aaaatttcat
      361 gtactgaatt attttattaa cataaacaat atcaaaaaag tataatataa ttcagttaac
      421 atatataaat gttttatgaa aataaaaagg agaaactatg aaaaaaaata ttaatagagt
      481 cattttgatt gttagtacaa tagttggtat tattatattt tcatatttgc agaacaattt
      541 aataagtgta aatgaagtta atatagcatc tagcaaaatt ccttcctctt ttaaaggatt
      601 taaaatcctc caactttcag atttacataa taaaaaattt ggtgaaaacc aaaatgtttt
      661 aataaaaaaa gtaaaaaact tgaaccctga tatcattgtt attaccggtg atttaattga
      721 cagtaaatca tataatgcag aaattagttt gcaagtaata cgagaacttg tgacggagta
      781 tccagtatat tttgtgacag gaaatcatga acagtggtca gggaaatata acagtttaga
      841 gaaagaattg aagaaatacc atgttacagt tttaagaaat gagcatgtaa gtattcaaaa
      901 agaggggcaa gaaataaact tgctaggtat tgatgatcca gaatttacta gtggaaatcg
      961 tgatgaagaa catattgtta aaaatgagat taggaaagct aaagatggaa tgaattcaga
     1021 cggttttaag atattactat ctcataggcc tgaattttta gaagcatatg ctgatgagca
     1081 agtagattta gtgttatcgg gtcatgcaca tgggggacaa gttcggttac cttttatcgg
     1141 gggattagtt gctcctaatc aaggaatact gcccaaatat acagtgggtt tatatgaaca
     1201 acaaaatacg tctatgatag ttagtagagg attaggcaat agtatcattc cgcaaagagt
     1261 ttttaataga cctgagattg tagtcgtgca gttaaattaa tctgtacggc ttttttgttc
     1321 aggagaataa tttaaaggta gtttttcttg agtacaagtt tccattacaa ttttgttaaa
     1381 atttttcaac gttacataaa gtaacaaaat ttgacctatt gagtttgtta tagtgtaaat
     1441 aatcaaaaaa cttaaaaatt agtcgagtta aaatagttat tattaagcaa tattaaaaat
     1501 ataaaggggt gtacaaatgc ataaagaatt tgaaattgaa gaatatacgg cgattgagga
     1561 gcaaattcat tattatagta cgtctttatt agtaagtcat cctgagcaaa ttgtaaagta
     1621 tttagaaaaa cggttggaaa agtatgcaga aacgttacaa tatgcacatt tatatccgga
     1681 aacggttata ttaccaatac agcaaatagt tatcgaatat tcattagatg ttgctagaat
     1741 tagaaggtat ttaaatttaa aaacataaca aaaatcgaat aattcacaat gaaacagagt
     1801 cgactttaag aaaagatatt ctaatgtcga ctctgtttca ttgatttagt aaataacaga
     1861 aaaaatatat gtttgaaaag tttgacatat aataattcga gagtaaaata aaagtgagta
     1921 ctcactcatt ttaaagaaaa gggggatttt agtgaagcaa ccttcaatta ttttacgaga
     1981 tgtatcaaaa agttttggaa aaaaagaagt tttgcataac ctttcgctgc aagtagaaaa
     2041 agcagaaatt tttggcttgg ttggaccttc cggatcaggg aaaacaacac tcattaaaat
     2101 gattgcaggt attaatgagt caactacagg ggatgtaatt gtttttaata caaacatgcc
     2161 taatctaaat gaaatgaaaa gaattggtta tatggctcag gctgatgcat tatacgaaga
     2221 actatcggca tatgaaaatg cagattttat tgcaacgatg tatgggttaa aaggtaagcg
     2281 taagaaagag agaatcgtag aagtttttga acttgtgcag ttatcagagc atatgaaaaa
     2341 gcaagtacag catttttcag gtggaatgaa aaaacgttta tcattggcga tagcactcct
     2401 tcatgaacca gaaatattaa ttttagatga gccaacagtt gggatagatc ctctacttcg
     2461 aaaatcgatt tgggagaagt tttatgatct taaaaagaaa ggcactacta ttattgtaac
     2521 aacgcacatt atggatgaag ctgagttttg cgaacgtcta gggctaatta gagaagggaa
     2581 tttagttgcg attggcacac cggaggaatt gaaaaaacaa acatcttctg gacgaattga
     2641 agatgtcttt atgttagaag gagtgattga atcatgagag ttaatggtgt agtcatccgt
     2701 atcattcgtc aattttttcg agataagcgt tctttagcaa tgatgtttgg ggcaccaatg
     2761 ttattacttt ggttattatc gctaatattt acacaaaaag actatatacc gcatattgct
     2821 gtagtcgatg tacctgctcc tatagtaaaa gcaatgaaaa atcaagaagc atcaatttat
     2881 gaatatagta aagacaaagc aatttcggaa ttagaaaagc aaaaggtaga tgcagtaatt
     2941 catttagaaa atggaaaaat gaatcttcta ttagaaggca gtgattcatc aaaaaaccgt
     3001 gcggtacttc aagtattgca aaagagtaca gagaagaata atgtatcaat gatgaagcct
     3061 gaagtggatt atttacatgg ctctaaagac attacgatgt tcgatgggct tggtcccgta
     3121 ttaattggtt tctttacatt tttctttgta tttatattgt ccggagtatc ttttgtaaga
     3181 gaacgtttaa gtggtacatt agagagatta ttgtccacac cagtgagaag atgggaaata
     3241 gttttaggat atattattgg ttttggaatc tttgcattta tacaatctat tataattgta
     3301 agtttttcag tttatatttt agatttatat gtagctggct caatatggct aacgctactt
     3361 ataacatgta tgctttcttt aactgcacta acattaggca catttttatc ggcatacgca
     3421 aataatgaat ttcaaatgat tcaatttata ccgcttgtta tcgtgccaca agtcttcttt
     3481 tctgggttgt ttccaatgga atccatgaat acatggttac aaatgttagg taaattattt
     3541 ccactcacat atggtgctga cgctatgaga caagtaatga ttcggaatca agggtttaca
     3601 gagattgcat tagatcttac tgtattacta cttttttcac tattatttgc agtaggaaat
     3661 gtatttgcat taaagaaaca tcgaaaaata taatgatgat aaaaaggagc acaataaatg
     3721 aagaaggatt ggctggaaga attagttgcc gcaacgaata ctgataaacg taatgaacgt
     3781 caaatgcgta tattagaggc agctgttgat atgtttggag aaaaagggta cgcctcaact
     3841 tcaacgagtg aaattgcaaa gcgtgcgggt gtagcggaag gaacaatctt ccgctactat
     3901 aaaacgaaaa aagatttatt gtttgcagtc gtaatgccga ctttaacaaa gttcgctgcg
     3961 ccatttttca tacaagcttt tgcaaaagaa atatttaaaa aggattataa atcgtatgaa
     4021 ggacttttaa gagtagtaat tcataatagg tttgaatttg ccaaaaagca ctttccaatg
     4081 ataaaaatac taattcaaga agtaccattt cagccggaac taaaaagtga aatacaacaa
     4141 ttagtagaaa cagaactgct ttcacatttt aaaaagttaa ttgtaaagtt tcaagaagaa
     4201 ggggaaatta ttgaaatgcc accatcttcc gtattacgtc ttactttatc agctgtacta
     4261 ggatttctct taacgaggtt tttattattg cctgaagaga aatgggatga tgaagtggaa
     4321 attgaaaata cgattcaatt tatattatat ggattaacac caagaacttc gctataacaa
     4381 catttgtgtt tttgattttc gtatttgtaa atatataatt taagaaaatt aatcgtaagt
     4441 aaagataagg tgatatatga attaaatata ttaacgtata ttaataacta attatacata
     4501 ttacttgtaa gcaaataata aatcgccttt aaaaaggcga tttatattca ttatatactt
     4561 ttaatacata agtacttgtt tactaaaaaa atgctctgaa ttagcgtgtt tctttgtctc
     4621 ttcttctaag acctaataat cctgctagtc ctaataaacc gagccaagcc caattattat
     4681 ttttatcgcg attatcattt aaatcatttg ttgtatttac atttcgagtt ctcacatcat
     4741 tattaactcg attcatgtta ttgtcattaa ctcgagttga catatcagtg ttattaactc
     4801 tattcatatg atttccatcg tattcagctt gggcagatgt gcctaaaaac ataatagata
     4861 gtgctaaaac acttaaaata gatgataatt ttttcttcat aaatttcccc tcctttctta
     4921 tgtattaatt tctccattgc ttttgtacat tattcgtatc acagtatcta aatcataaag
     4981 ttaaaattat tagaactatc tttaatctcc attattaaaa ggacaggtaa atacaacgaa
     5041 gcggttaaca aaagttaacc gcttatgcca tgttatgctt gatcagattg aagaacatgt
     5101 aaaggaggag gaataatcca accttttttc ttatttaatc gtagtaaagt ggcacctgct
     5161 tgtgcttttt tcatatggaa ttgtccaaac atcattccta cgtcttctcg aagtgattgt
     5221 cccatcgctt ggctacatgc tactagtcca gcagcaagat ccatagaaac tttagctgca
     5281 atttctgcgt cattaatacg agcaccagga gggattgttt caatagatgc aactggacgt
     5341 tctggaggtg ctggtggtaa tgccaccccg tttgatttca acaagttttt tagttcttca
     5401 acttctgatt ggatatcatt ttctataaga ttttctaaaa acttttttaa gtcctcgtct
     5461 ccagtatgat tgacaagaac ttggtaacca gcaattgcac cttgtgcgcc tgcaagataa
     5521 ctccaaattg caaagacttc tccgtaatgc attggttcat tttggggatt accacttaat
     5581 actcccattt taatatgcct ccttaaactg aatggatttt ttaaaatatt ttttaccaaa
     5641 gaaaaaatgc ttctgaaaat gttccgtaat aaagaaatta ggtttctaaa atgcatttgg
     5701 aacaccctaa ctacaagtaa tactttctca gtctataatg tacaaatata aagaatatat
     5761 tccaaataac ttgggattaa aattcgtatt aagacttatt ttaatttaaa tgtaaagagg
     5821 agaggaaaca ctctgtaaat atgctagtaa agatggattg tgtttagaca aaaaagtgtt
     5881 aacaagtttg tacaagaact tgttaataca tatacgaaat agatttgaat tgcagttgat
     5941 atagcattaa atttatagtt attataaaaa taatcaatat aaacagactt tgcttaagat
     6001 actaatatca gtacaattta gattgtatgg attgatacca tggaggtaat gaaatgcggc
     6061 aatttgcaaa accaacaatt gttgtaagta aatgtttaga atttgatgcc tgtcgttata
     6121 atggagagat gataccagat gtaacaattc gaaacttgca gccatttgtt acatttatac
     6181 ctgtatgtcc tgaagtagaa attggtttag ggactcctcg tgaaacgata cgtattgtag
     6241 aaaaaaatgg tgcgaatagg cttgtacaac cgtcaatacg agaagatgta actgaaaaaa
     6301 tgaatgaatt ttcaaatgca tttttacaaa cattacctga agttgacggt tttattttga
     6361 agaatcgttc gccaagttgc ggaactcgtg atgtgaaaat ctattctagt tttgaaaaag
     6421 ggccagtaaa aggaaaagga actggattat ttggcggagc agtaataaaa aaattttcgc
     6481 atcttccaat tgaagaagaa ggtagattgt cgaattttat tattagagag catttcttta
     6541 caagattgtt tacaatcgcg cattacaaaa tgattaaaca tactaaaaac ataaaagaac
     6601 tcgtagcgtt tcaatcagat tataagtatt tatttatggc atataatcag gtgaaacaaa
     6661 aagaattagg gcgtattatt gcaaatcaaa aaaatgaaac aattgaagtc gtatttgata
     6721 actatgagaa gactttatat gaattattta tgcgcgcgcc tcgctataca tcgaatgtaa
     6781 atgtatgtga gcacattttc ggatatttta aaacaaagct aaaaaaacaa gaaaaagatc
     6841 attttctaga actgatacaa aaatatgcag aaaagaaaat accacttagt agtttgctta
     6901 caattttaaa atcatgggcc attcgatttg atgaaaagta tttattaaga caaacatatt
     6961 ttgagccata ccctgaaggg ttagtagaaa tttctgattc gggaaaaggt agagattatt
     7021 aaacaataaa ttacataatt cgacacaaaa cctcctatgt tgttgtagaa caatgtagga
     7081 atttttttgt gcattagtac agaatctgtt ttaaaattaa gttatgacag aattatagca
     7141 attgtctaac taatattcgt gtcttttaag aagtaatgtt tgtagtagaa actcgcacgc
     7201 tgtcgaaact caatattcga taaggggtgt gtagcggaat ggaatttact ctaactcgcg
     7261 aaaaacaaat gattaaagaa atggtacgtg attttgctga aaaggaaatc gcaccgaaag
     7321 ctgtatatta tgacaaaact gcggaatttc catatgaaac atttcaaaaa atgggtgaac
     7381 taggattatt aggtatccca ttcccggaag agtatggagg ttcaggtggc gatacgttat
     7441 cgtacgcgtt agctgttgaa gagattggtc gtgcttgtgg tggaacaggt ttaagctatg
     7501 ctgcaacaat ttcattaggt gcttctccaa tttattattt cggtacagaa gaacaaaaac
     7561 agaaattttt agttccaatg gcgtcaggta aaacgttagg tgctttcgga ttaacggagc
     7621 caaatgctgg atctgatgca gggggcacac aaacgaaagc aattttagat ggcgatgaat
     7681 atgttattag tggtgaaaag tgctggatta caaacgcaga gtatgcaaat acaattattg
     7741 taaccgctat caacggtttt gaagacaatg gtaaaaaacg tatttctgca tttatcgtac
     7801 cgactactag tgaaggatta acgatttcaa gcccttacga taagatgggt gttcgtgctt
     7861 ctaatacttg tgaaatcgta cttgatggtg tacgtgtacc gaaagaaaat attcttggtg
     7921 atgtaaataa aggatttaaa caattcttat atacgcttga tggaggacgt atttcaattg
     7981 cagcattagc agtaggtatt gcacaatctg catttgagcg tgcattgcaa tatgcgaaag
     8041 aacgtcaaca atttggaaaa ccgatttcta atttccaagc gattcaattt aaattggctg
     8101 atatggcgac tgaagtagaa ttagcgcgta atttagtaca taaagcagct tggttaaaag
     8161 ataacgataa acctttcggt aaagaagcgg ctatggcaaa gttgtttgca tctgaagctg
     8221 caagtcgtat agcaaatcat gcagtacaaa ttcatggtgg atatggctat atgcgtgaat
     8281 atgaagttga acgatatatt cgtgatgcaa aacttttaga aattggtgaa ggaacttctg
     8341 aaattcaacg tctcgtaatt gcaagacatt taggatgtag ataaaaagga ggggtcacta
     8401 tgtttcaaaa aatattaatt gctaatcgcg gggaaatcgc agttcgcatt atgaaaactt
     8461 gtcaaaaact tggcattcgt accgttgcta tttattctga ggctgatgaa aatgcccttc
     8521 atgtaaaatt ggcaaatgaa gcttacttag taggcggtcc acgtgtccaa gaaagctatt
     8581 taaaccttga aaaaattatt gaaatagcta agaagacaaa tgctgaagca atccatccgg
     8641 ggtacggatt attatcagag aatccatctt ttccgattcg ctgtaaagaa gaaggaatcg
     8701 tatttatcgg tccttcagaa gaaatcatta ctaagatggg aagtaaaatt gagtcacgta
     8761 tagcgatgca agaagcagat gtgccagtag ttccaggcat tactacaaat attgaaactg
     8821 ctgaagaagc aattgaaatt gcgaaacaaa ttggttatcc attaatgctt aaggcatccg
     8881 cgggcggcgg aggcattgga atgcagttga tggaaactga gcaaacgctc accaaagcat
     8941 ttgaaagtaa taaaacaaga gcgcaaaatt tctttggtaa cggagaaatg tatttagagc
     9001 gctatatagc agatgcacat catattgaaa ttcagctttt agcagataca catggtaata
     9061 cagtgtattt atgggaacgc gaatgttcag tgcagcgccg aaatcaaaaa gtaattgaag
     9121 aagcaccttc accattttta gatgagggta cacgaaaggc tatgggagaa gttgctgtac
     9181 aagctgctaa agcacttggt tatacaaatg caggtacagt tgagtttctt gtagatgatc
     9241 aaaagaactt ttatttctta gaaatgaata cgagattaca agtagaacat ccagttacag
     9301 aagaaattac tgggttagac ttagttgaac aacaattact tatcgcatat ggtgagaagc
     9361 tatcatttac acaggatgat gtaaaacgta gtggtcatgc cattgaggct cgtatttatg
     9421 cagaagatcc gaaaacattc ttcccatcac ctgggaaaat tacagattta acgttaccga
     9481 caaatatacg tattgatcac tttttggaga atcaagtaac gattacacct ttctatgatc
     9541 caatgattgc gaaagtaatc gcacatggtg aaactcgtga agaagcgatt tcaaaattaa
     9601 aaattgctct agaagagtta aaagtagaag gtattaaaac aaacacacca atgttactgc
     9661 aagtactcgg agacgatgtg ttcaaaagtg gtatttatac aacaggtttt gtaacaaaac
     9721 aacttgttaa aaaataagag ttatgaatat taagggggaa aaaatgatga cgaaagtata
     9781 tgcatcgatg gcaggaaatg tttggaaaat tgttgtagga gtaggagata cagtagagga
     9841 agagcaggat gtcgtcattt tggaatctat gaaaatggaa attccaatcg tttcagaaga
     9901 agccggaact gttatgaaaa ttaacgtaca agaaggcgat tttgtaaatg aaggagatgt
     9961 attactagaa attgaatagg gagatatagg gggaagcgaa ttgaaactac ctaattttgc
    10021 tgtcattaaa gaagtcgggc cacgtgatgg cttacagaat gaaaaaaaga ttgttggcac
    10081 aaaagataaa gtaaaatgga ttcaactact tacagaagcg ggattgtcgt acgttgaagt
    10141 ttcctcattc gttcacccta aatgggttcc tgcattagca gatgcaagtg atgtattttc
    10201 tgagctaaaa agggatccaa atgttacata tgcagcgctt gttccaaatc aaaatggttt
    10261 ggaacgagct tttttgcaaa atgtagatga ggtgaatgtt tttttatcag caagtgaatc
    10321 tcacaataaa agtaatatta ataaatctat taaagaagca ttagctgtaa ttgaagatat
    10381 aacaaaacag gcaatgttcg aagggaaaaa ggtaaggggc tatgtttcta ctgtatttgg
    10441 atgtccttat gaaggcgata taagtgccac agcagttgac gaaatatgta atcaactatt
    10501 ttcatacggc atttatgaag tttctctcgg tgacacgatt ggtgtagcga atccattaca
    10561 agtagaacaa gtattagaac atctattaaa gaagtatgat gcttcgcagt ttgcaatgca
    10621 ttttcataat acgtatggaa tggctctggc gaatgtagtt aagtctttag aatatggtat
    10681 tacaacgttt gatagttctt gtggtggact cggaggatgt ccttatgcac caggagcatc
    10741 gggtaatgtt gctactgatg acttagtgca tatgctccat aagctaggag tccaaactaa
    10801 tattgatgaa gaaaagttat tgagagctag tcattttatt caaagtaagt taaatatcca
    10861 attaccgagt catgtgtata gagcgcttca acataaaacg ataagtaggt gagaagatgc
    10921 tacaattaca aaacatttca gttgactatg ttacaccgca cgttgtaaag atttcgttaa
    10981 atcgtgaaag acaagcaaac tcattatctt tggcattatt agaagaatta caaactatat
    11041 taactcaaat aaacgaagaa tcaaatacgc gcgttgttat tttaacaggg gatggcgaaa
    11101 aagcattttg cgctggtgct gatctaaaag agcgtgtcaa catgagtgaa gaacaagttc
    11161 gccatgctgt gggtatgatt cgttctacta tggagatggt ggaacaatta ccacaaccag
    11221 ttattgctgc tattaatgga atcgcacttg gtggaggtac tgaattaagc ttagcttgtg
    11281 attttagaat tgcttctgac actgcaagtc taggtcttac tgaaacttct cttgcaatta
    11341 tacctggagc aggtggtact cagcgtttac cgagattaat tggagtcggt agagcgaaag
    11401 aattaattta tacaggaaga cgtatttcgg cgcaagaagc gaaagaatat ggtttagtag
    11461 aattcgtagt accagctgat ttactagaag agaaagcaat tgaaattgca gatcgaattg
    11521 ctaaaaatgg tccaattgct gttcgattag caaaagaagc aatttcaaat ggtattcaag
    11581 tagatttaca taccggatta caaatggaaa aacaggcgta tgagggcgta atccatacga
    11641 aagatagatt agaaggatta caggcattca aggaaaaacg caaaccaatg tataaggggg
    11701 agtaaatatg ttagatcaaa aacaacaatc taattcattt gaagaacgag ttgaaacaat
    11761 taagcaaggc ggggcaacga aatatcatga acaaaacaaa gcaaaaggaa aactttttgt
    11821 tcgagatcgt ttagctcttt tattcgataa tggtgaatat gtggaagatg cattatttgc
    11881 aaattgtgaa caaaccgggt taccagctga cggcgttgta actgcaactg gtaaaataca
    11941 tggtcgcact gcgtgcgtaa tggcaaatga ttcaactgtt aaggctggat catggggagc
    12001 acgtacagtt gaaaagattt tacgtattca agaaacggct gagaaattac gtgtgccgtt
    12061 attttattta gttgactccg ctggggcacg tattacagat caagttgaaa tgttccctgg
    12121 acgccgcggt gcgggaagaa ttttttataa ccaagtgaaa ttatctggaa aagtgccaca
    12181 aatttgttta ttatttggac cttcagcagc tggtggtgca tatattccag cattttgtga
    12241 cgttgttatg atggttgaag gaaatgcttc tatgtattta gggtctccgc gtatggctga
    12301 aatggttatc ggtgagaagg taactttgga agaaatgggc ggagcacgta tgcattgctc
    12361 agtatcagga tgcggagatg ttttatgtaa aacagaagaa gatgcaatta cgcaagcaag
    12421 acaatatatt tcttattttc caagtaacta tttagaaaag actcctttga ttacacctca
    12481 agaaccgaaa cagttcgata aaacgttaga agaaatcatt ccagaaaatc aaaatgctcc
    12541 tttcaatatg aaagatctca ttaacagaat tattgatgaa ggttctttct ttgaagtgaa
    12601 aaaattattt gctcaagaac taattacagg tttagcacgt attgatggta agccaattgg
    12661 cattattgca aatcagccgc gtatgaaggg cggcgtatta ttccacgatt cagctgataa
    12721 agcagcgaag tttataaatt tatgcgatgc ataccatatt ccattattat tccttgcaga
    12781 tgtacctgga tttatgattg gtacaaaagt agaacgtgcc ggaattattc gtcacggtgc
    12841 aaaaatgatc tctgcaatga gtgaagcaac tgtaccgaaa atttctatcg tcgttcgaaa
    12901 agcatatgga gctggcttat atgcaatggc aggtccagcg tttgaaccag attgctgctt
    12961 agcattacca acagcttcta ttgcggtaat gggtccagaa gcagcggtta atgctgtata
    13021 tgcaaataag attgcagctt taccagaaga agagcgtgca agctttattg ctgaaaaacg
    13081 agaagagtat aagaaagata ttgatattta ccgtttagca tctgagatgg tgattgatgg
    13141 tattgttcat ccaaacaatt tacgtgaaga gttaaaagga cgattcgaaa tgtatatgag
    13201 taaatatcaa gtattcacgg atcgtaaaca tcctgtatat ccagtttaaa agccctattt
    13261 agggctttct tgctcaaaaa atcaaggagg ggaaaacatg aaacaagcag tttggtttcc
    13321 aacagaagaa tataaagaaa aaacgcgttt atttggttgg atgaaatcat taggctatga
    13381 agattacgaa gctttttata ataagtcaat tgaagaaaca gcttggtttt ggggagaagc
    13441 tgagagagca gttggctatc agtggatgaa accatataca gaagtgttag atttagaaaa
    13501 tggtacaccg tttgcacagt ggtatactga gggaacttgt aacgttgtag aatctgcttt
    13561 atctcgctgg cttgcagacg ataaaacgaa aacacaagca gcacttatgt atgaagggga
    13621 aaacggaact tcgaaatcat ttacatatga agagcttgac agctgggtaa gccgtgttgc
    13681 caacggtttg aaacatgctg gtattgaaaa aggtgatcgt gtaacaattt acatgccaat
    13741 gattcctgaa acagttgttg ctatgttagc ggtaatgaaa attggagcga ttatttcacc
    13801 aatattctca ggttttgctg ctgatgcagt aatgacacgt gtacaagcag ctggttcaaa
    13861 aatggttatt accgcagatg gcttttcacg ccgtgggaaa attgtttcat taaaagatga
    13921 agtagataaa gcttgtgaac attgtccaac tgttgaaaag gtggtaattg ttcgtcatgc
    13981 aggaaatgat tttacaccgc ataattatga tttttcatgg agtacgttag aaaaagaaaa
    14041 accatttata catgctgaag aaatgaacag tgatgatcca ttaatgctta tatatacatc
    14101 tggaacgact ggtaagccga aggggacagt acacacacat gctggtttcc cgctaaaatc
    14161 tgcatttgat gcaggatttg gaatgaatat aaaacaaggc gaccgagtat tatgggtaac
    14221 tgatatgggc tggatgatgg gaccattttt actattcggc tctttaatta atggcgcaac
    14281 aatggttatg tatgaaggtg tcccagactt tccagaagca gaccgcttat gggagacagt
    14341 cgataaatat gaaattactc atctcggtat ttcaccaacg ttaatccgtg cattaatggc
    14401 aaaaggtgat gaatatgtaa ataaacactc gttaaagagt ttagaagtat tcgcatcaac
    14461 aggagaacct tggaatccag acccatggat gtggttattt aatacagttg gtaaaggtaa
    14521 agtaccaatt tgtaactatt caggtggaac tgaaatttca ggtgggattt tcgggaatgt
    14581 cctaattaag ccgatcgcac cgattagttt taacgcatct ttaccaggaa tggcagcggt
    14641 tgtacttgat gatcaaggta aaccaattcg agatgaagtc ggagaattat gtttagaaaa
    14701 accttgggta ggtatgacga aaagtttctg ggaagatgat gaacgttatg taaacacata
    14761 ttggtcacgc tttgaaaata aatgggtcca tggggactgg gttatttatg acggtgagca
    14821 atacatcatc acaggacgtt cagacgatac gctaaatatt gcagggaaac gtattgggcc
    14881 tgctgaatat gaatctattc ttgtgaaaca taatgaggta atagaagcag cggcagttgg
    14941 tgtaccggat gatgtaaaag gagaagtttg tcattgtttt gttgtattac gagatggtgt
    15001 aacattctca ggagaattaa agaaagaatt aatgagttta gtaaactctc atattggtaa
    15061 agctttatgt ccaaaagaca tccacgttgt agaagattta ccaaaaacac gaaattctaa
    15121 agtaatgcga cgtgttatta aagcagctta cttaggaaaa gagttaggag atttatcgtc
    15181 acttgtaaat cctgaagtag ttccgtttat tcaggggtta cagtctagca aactataaaa
    15241 ttacgaatga gctctatgta aatagagctc atttttaatg tttacaaaaa gataagagag
    15301 aaaaagtaaa tttgaagtta aaaaatctac tattagtgtt aagtatatct gtttgttttt
    15361 agtttttatc aaaataggat actatggctg tctattcaat ggagtgattg aattttgtta
    15421 agaatgaaaa tttagtgaag aaaaaagtaa tgaataaaag gagaaatccc tgggggacag
    15481 ggattcaata agggagatat cattgtcgtt caatgtcgaa atttggcgta tccgacaaat
    15541 taatattatc acgaattttc aggagattgt gatagtggat gtgtcaaaaa tgtgtacggg
    15601 tttcatataa aagtgttatt taaataggaa aagggaaaag aattaagttc actcgttctt
    15661 aagatttttt cccttttaaa tttactgttt gttcgttgtt ctatatacat ctgaaattgg
    15721 taaatcttcg ccatgtaaag cttgagtact gtcctttttg tttgaattat gtgcctcctg
    15781 agatgtttct tgcagttgtt cttgggcctt actaggggta ttcagcgcat ctaatgacac
    15841 aggatcaagt tgttgactta ataaatcttt tttatccatg ttatgtagct cctttttgaa
    15901 cttagatata aaaacaaagt atttttaaat agttacgtgg gtattatgta tctttgaatg
    15961 gaattatata cacaaactat attgagaatt taactaatta taaaaattac ttgtgatgac
    16021 aagcttaaga aatataaaga tcatgagttc ttaataaaag cgttatttta gtagggtgtt
    16081 acgaaatttc atttgaaagg aacatcccaa tgataaaaaa gagcactgta aatcagtgct
    16141 catcttatta gatattgctt agtccttaaa aataaaacca ttacggacaa ttcacaatgg
    16201 taatagtgac gctagccatt gttccaggag aatcaagaag tgaagcagta acggttactg
    16261 ttccagaccc attagcggct agaaataaag cggtaaagtt acctaaagaa ttggtaatga
    16321 cagcaagagg aaccatgaaa gcaagagaag ggttactaaa tgaaaaactg accactactc
    16381 ctggagtagg actaccgttt actaatactt gacccgaaaa aaataaagta ttatttcctt
    16441 gagtggatac acatgctgtg gtttcgttag aagtcaaggt aatagatgca ggcccagcag
    16501 gaagattaaa tccagttggt ccggtagaac cagtagagcc agttgatccg tttgatccgt
    16561 ttgatccggt tgaaccagtt ggtccaatta atccagttga gccagtagct cctgtagaac
    16621 cggtgggacc agtagggaat tgaaagggtt gaacaggtgg aagtgtaggt ccaatagaac
    16681 ccggattaag tgcagcaaaa gataaaaact cgtccattat atattacctc taaaaatcgt
    16741 attactaata gtaaatgtaa tgatagagca aagtgaaatg gacaagcggt tgtattttaa
    16801 taaattaaac aaaatagtta tttgatagaa agagagatta gtatgattac tttagaaatt
    16861 aaatataaaa aggcgattat cttcatatcg ccttttggat aatatagtgt aattttattc
    16921 agttatttga aatatagttt cattcggttt ggaaaatcca tacagcttcc ttgcgaattt
    16981 taaaacttct tcttcactac ctgttaaaac tttaacatca tttttaaggg tatgaccatc
    17041 cttctttaaa gtagataatt tttgttgctc cgtattaacc gtgatttgtt tctctttaat
    17101 catttcttgc tggttattaa gagaatattg aaggacaaaa attataggta atataaaagc
    17161 taaagtagtt ataatacggc gtcttgtttt tttattatta cctagtttgg tgttagcgtt
    17221 cacttgctgt gagggtatct taggatttga ttgttgtgat gatatttttg ggatgtttcc
    17281 cattaaaatg cctccattac tgattgtaga atttaaaccg tttaaaagta ttataaatgt
    17341 tcaatgggaa ttttagaaga tagtttaata taggtgagtt ttgtaaagtt taaacaaaat
    17401 ccttatttaa ataaaaggaa ccccgattgt ctgcggggct cctaagggta atcgtcaagt
    17461 aatgacgtac tcgactagtt aacgatatca tgaatttttt ggtaaatata ctggtaaatg
    17521 cgtccaaatt aatgagagca ttatttgaaa caaaaatgct attttaatag ggaggggaat
    17581 aatgatgatt ccatgggaca agcgagtata cattgtatca aggtgatcat tttattacag
    17641 aggggacaat tttagaggtt agtgaaaagg cgaacaaatc attatattgg cgttggtgca
    17701 tgttagctcc aagctatgaa aaagtgtgcg gtaatagtac aaagcgactt cggttgattc
    17761 ggatagatga tgatgatgaa tgatataaaa atttcatttt gtagagaaat gaggtgatta
    17821 aggatgggca tagaatatgc catgtttgta ttaaaaaaga gcagaattta gcctatatat
    17881 aaagattttg gaattgttct aaagggggga atatctgaaa tataaataat tgaggggagt
    17941 gaactaataa tggaaactag tactttttta ggattgtttt ggggatggat aacggttatc
    18001 gtatcgggaa tacttttcgt acgtccatcg gtactacgtg aattgaaaaa attagtggtt
    18061 gaagacagag gatttggtat tatgtatggt tttctatcga ttttcctagg gttaggtagt
    18121 gtaatcctac ataatgtatg ggtattcaat tggcaggggt tcctaacggt tattgcatgg
    18181 cttgcattat taaagggaat ctacataatt gcatatcctg aaccctccaa gaaaacagac
    18241 tttgaattaa gggtactatc tacacgtata gcgctcgcta tcattggcgc cttggcttta
    18301 tggatgctta tagtaatcta tataaaataa tccttttcta ataagaacta tattaaaata
    18361 aatctctacg tgttcattga caaaaagctg actatactta gtcagctttt tgtatattac
    18421 attctagtat ttatcggtca caaaagacat gttctctctt tcaagtcgat attgaaaaca
    18481 ttaccaattt tttcttttac aatgacaaca aataaagaaa catttacaac gacacttatt
    18541 tcgtttagaa ctccaatcat catcacaatg attcttttct ttagatttcc accaatcatc
    18601 attacaatgc ttttccttag aactccaatc atcatcacaa tgattctttt ctttagattt
    18661 ccaccagtca tcacaacaat gctttttctt agaactccag caatcatttt tccaggacat
    18721 tcttttatac ctcccttcaa taggattcat actattctat gttttagtaa aagaatggct
    18781 tgtttattaa cctattattt tacctttata tgatagagtg ctttctacta gatatagaat
    18841 tcatacaaac tatgctaatt ttcaagagat agttgagaga actactggtt atgatattaa
    18901 tcaaaaaaca cttgttgaag gaaacgttaa gattttaaat aatatcttat tttggagtac
    18961 gcttttctga atgtatattt cacaatggta aaggaaaaat acaccatatc actgcgaaca
    19021 aagcctatgt atatgtgaag taataggaaa aggtggtccc tattcaagga gccggcttat
    19081 taaaagtata aataagaagg tttagtacaa gtgtttgttt ttttgtttct atgcatttgt
    19141 ctcgtacact tttaagctgt tggacatact ttactagtag aaaggattag ggggtgaggt
    19201 tttgggttct cgatttaata attgtagaaa gaaatgtacg tgtaagcatg atgattgttg
    19261 ggacattttt gaagagtgta aaaaggaaaa gaatgagaaa tgtgacagct cttgtgtaca
    19321 aggaattaga gatgagctta aaaaattaat taataaaaca gtgcgaatta acactgaagg
    19381 acgtacttat ataggtactg tttcttcggt aacttgcgat gttgttaagc tagctgctat
    19441 tcctggttca gttgcagcaa ttatatctct ttgtaaaatt gaagcaattt taccacctgc
    19501 tacaactgtt actgatgagt ttgattttaa cggtgttgac gtagcaaata aagattaatt
    19561 atgctttatt gatgctaagc cattcttatg aatggctttt tattttgttt aaaagggaat
    19621 atatttttca tatagaaata aatttgaaga tgtataaaag gttgtgtgaa aggagaatga
    19681 gagtgatcaa gctgaaacaa tttacaagat ctgatttcaa acaattaata aattggatta
    19741 attccgaaga atttttaata caatggtcgg gaaatgcatt cacatatcct ttaaatgaac
    19801 agcaattaga gaaatataca gaaagtgcaa acacactggc attcaaaata atggatgaag
    19861 agactaaagc agttattggt catatttctc ttggacaaat agataatata aataagtctg
    19921 ctagaattgg aaaagtgcta gttggtaata cgaaaatgag agggcgttct atagggaaac
    19981 atatgatgaa agccgtactt cgtattgctt ttgatgaatt aaaactacat agagtaactc
    20041 ttggtgttta tgactttaat aagtcagcta tttcttgtta cgaaaaaata ggttttgtaa
    20101 aagaaggttt attaagagag tcaaaaagag taggagaaac gtattggaat ttatgggaaa
    20161 tgagtatgtt agaatatgaa tggaacaata aataatagta ttttataatt atattatgtt
    20221 aacaaaaggg gtttggtggg aatcgtgaat aaaaaacaaa aataatttca attgcagctg
    20281 tttcaggggg cggtaaaact accattacag aaagtttagc tcatgagttg aaaaactcaa
    20341 aggctctata ttttgataga tataaatttg ataactgttc tgttgatatt tgtaaatgga
    20401 ttgatgatgg agctaattac gatgaatggg tacttacacc gctaatgaat gatattcagc
    20461 gttctataca agatagtagt ttagattata ttattgtaga ttatcctttt gcatacttaa
    20521 atagagaagt gggacaattc attgatgtaa ctatatttat cgatacacct ttagatattg
    20581 cgatggctag aagaattttg agagatttta aagaagatac aatgagtgaa atacataata
    20641 atttgaaaca ttacatgaca caggcgagaa aagcttattt agaggcaatt catacggtta
    20701 agccgcattc ggatattgta ttggatggat ctttatctat aagtgaaata attgatcaaa
    20761 taatagagga acttaatcga agagaagtga ttgtgaatgg ttaaatgtat aaaacgatat
    20821 gtacaagtca ttatctgatt tatatagacg agaattagat aactttttgc agttatggtc
    20881 tggcgacttc gaatcaaaaa tattgaaagc ttcatggaca gataaatcat ataaatacgg
    20941 tgaagtttta aggcatgtaa ttgtacatga aattcatcat attggtcaga tatctatatg
    21001 ggcaagagaa ttaaatcttc agcccgtttc agcaaattta attggaagag gattgtagat
    21061 ttagaaaccg acttgcagtg taaacgcaag tcggttttta tatataagaa gatttcttaa
    21121 ttaaaatcct cggctttttt ttgacgtata tataaaaaca ttaagattgt aatgatgaaa
    21181 aagatcataa tcgtttgtat gattaaattt ttaaactgaa acaatattgt ccaagatgta
    21241 acagcatctt taaaagcttg gagtgcagag tacgaggaag gatcaaaacc gtactgaagt
    21301 aacttttttg tttcaataaa agtactgttt tcatcaccgg cgtctaatat tactgaaata
    21361 agtctagtat ctcctcgtgt ggctgtactg acaaaactat aattaccatt agttgaaaaa
    21421 ctagtttgta agccgtcaac accttggagt ttaatgtttt tattaaggga atatatcatt
    21481 ttatttgtat tgaaaacttt tgaatctttg aaggtaaatt ggtaagaggt tagtttcgta
    21541 acattcaata catctggaaa gtcttttact aattgtgttg ctagtttagc gacgtctatc
    21601 gatgttgtag ttgattgttt attcgtatcg ttattaattc cagtagcatt tagaaacggg
    21661 gatggttgtg ataactttag ttgttttgct ttgtcattca ttaaaagtgt aaagttatct
    21721 tcgtttccag caatgtgttc tgcaagggca agtgcggaac gattattccc tgtcaaaaac
    21781 aatgcatgaa gtaaatcacg aaccgtcgtt ttatctttcg aagttacttg tataggactc
    21841 gtttctgctc ggaaaacttc gttacttatt tttactaatt catctaactg tatttttcct
    21901 tcattcagtt gttccagtgc gatatactct gtcattaatt tagataaagt agctgattgt
    21961 ataggagttt cttcattttt tttataaaca atctcaccag aattagtatc tattaaagta
    22021 gctgatttag cttgaataat tggaccattt acataaagat aaaaatataa aacgataagt
    22081 gcagtaataa gaaaagataa taataaaact gttatttttt ttaagaattg cattagcgat
    22141 cctcctacta ttacatcaat aatattattg taaaaaggaa tgcttaatta ggaagaaaga
    22201 aaaggtaaag aatttctaaa gaattataaa ggattattaa attttggata ttgatggaat
    22261 ataaaaggtt caatttctta tatgataaaa aattgaacct ataaatatgt ggtattaagc
    22321 tttataaggg agtaatttta cagtgaaagt tgttttttta tcatcgctat atacttcaat
    22381 tgttccttta tgcaattcaa caatactttt tgcaattgct aatccgagcc cagatccacc
    22441 agtgtttgtt gaacgtgatt tttcaacacg ataaaaacgt tcaaaaatat gaggtaaatc
    22501 agtactaggg ataggttgtc cgtaatttgt tatatcaatt gtaatcatgt tattgctttc
    22561 gtaagcggta atatcaatat gatctccatc atttccataa gtaatagcgt ttatgattag
    22621 attttcaaac acacgtacta atttatcccc atcagctagc accattagct tttgagatgg
    22681 gaaagaaggg cgacattcaa tattagcttc ttgaagctgt atccgaaatt ggacagttaa
    22741 ttgtccaagc aattctacaa tatcaatggg agcagaatat aaacttaact ctttattttg
    22801 aacgcgtgta tattcaaaca agtcattcat taatgcatta agacgagtta ctttatcgta
    22861 aatgacttga atatagtatc gtaattctac ttcatctcta taattatcat gatggattaa
    22921 atttacgtat ccaactatag atgtaagagg ggttcgtaaa tcatgtgata catttgtaat
    22981 aagttcgctt tttgcttgtt ctgcctgtct ttcttcatca attgatactt ttaattgctc
    23041 aataatttga ttgaccccag ttgccagttc ttctaaataa ttatggtgta cgatggaaac
    23101 tttatgatta aagtttccac ttgcaatata ccgaatttct tcaatcattt tttttataca
    23161 agtttcatag taaacctttc tttcatgacg ataaaaaatg tataaatagg atgagaaaat
    23221 agaaaataaa aacaaataag atacaatcat catccataaa gactctttta atccaatata
    23281 tttttcatgg ccaaaaattc taatgaattc ttttcctagt tcgcttagag taagtgaact
    23341 ctcaattaca ctcgttacga ggcgaaatat aattaattcg gtaattggtg taagagtgat
    23401 agctaataaa agccaaaaaa taagcttcca cttgggtata tcttttaata tatcaaatgc
    23461 ttcatttctc aattttatat cctactcccc aaaccgtatg aattagtttt tcaccattca
    23521 ttacggtttc aagtttatcg cgtaaattac taatatggac cattaccgtt ttattagaac
    23581 cataaccgtc ttcattccaa actcgttcga atatctcttc agagctaaat actcttccag
    23641 tattactcgc tagtaaatat aaaatatcaa attcgataga ggtgagttta atatattctc
    23701 catttacttt aacagtatga ttatgtttat gtatttcaac agaacgaata cgaataatac
    23761 catcttcatt cttttgggaa gtagcatttt ggaaagagga tcttcgtaat aaagctttca
    23821 ctctagccac taattctagt ggattaaacg gtttaatcat ataatcatct gcgccggtca
    23881 taagtcctaa aattttatcc atatcttcag cctttgcact aagcataagg ataggtacag
    23941 tattattttc acgcacttct tgacaaactt ccaatccgtt tcgttttggc atcataatat
    24001 ctaaaagcat aaggtcaact tcatatgtac atatcatttg taatgcttca tcaccatcat
    24061 aagctttata aatgttatag ccttcatttc gtaaataaac agccagtaat tctacaatat
    24121 ctttatcatc atcaataatt aatatgtttt tattcatttt atagttagtt cctttcctta
    24181 caattaatca acattactat aatatcaaac atttatgtat tttgtagtaa tgtttctaca
    24241 taaaatttca tgtatcgtat taaaaaggaa ttaaaacatt cataacgaat ataaaataag
    24301 aaggatattt aaactccaca ttatactgaa agatagttat aagggggact tgctatgtta
    24361 tataatgata tatattcatt tactccaact ggaaaaatag aaaatgatat taaagctttt
    24421 ctattaaaat acaataaaga atttacatat aaacattcaa ttcgtgtggc aaatgaggcg
    24481 agaaaaattg cgaaaatatt ttatgaagat gaagaaaaag cagcgattgc agggtgttta
    24541 catgatatta gtgcaatctt tccgaacgag gagcggatta cagttgctga aaaatttgga
    24601 atagaaatat tacaagaaga acgagaattt ccaatgatta ttcatcaaaa attatcgaga
    24661 gtaattgcaa aagaggtatt taaagtagaa gataaagaag ttttaaatgc tatctgttgc
    24721 cacactactt tgcgtaaaca tgcaacgaag atggatttag tattatttat tgctgataaa
    24781 ttagaatggg atcaaatagg gacacctcca tatttaataa atgtaaaaaa agctttagga
    24841 aattctttag aacatgctgc ttttgtatat atttcatatt tgtgggaaag aaaagataca
    24901 ttaaaagtca tacacccgtg gttagaagaa gcatattggt atttaaaaga aattgtagag
    24961 tagaaagggt ataaaaatgc aatttaaaga atatatgaat caaacatttc caggagttac
    25021 gctagtaccg tacatatact ctcagtggga aaatcatctt cattttgatt ttgggaaaga
    25081 taaatatcaa ttcaaagaag atggtaacac gtataatatg gaatatttca cacaactata
    25141 taggtataat aaaagtctat ttaaagatat attttcaaaa gaagataccg tctttttagt
    25201 cacaaatgtt tatcgattta aacaggaaaa tataaaaa
//
