LOCUS       NZ_CP093291            23535 bp    DNA     circular CON 24-MAR-2024
DEFINITION  Bacillus mycoides strain DSM 2048 chromosome, complete genome.
ACCESSION   NZ_CP093291
VERSION     NZ_CP093291.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5285600)
  AUTHORS   Chiba,A., Peine,M., Kublik,S., Baum,C., Schloter,M. and Schulz,S.
  TITLE     Complete genome sequence of Bacillus mycoides, isolated from an
            agricultural field in Rostock, Germany
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5285600)
  AUTHORS   Chiba,A., Peine,M., Kublik,S., Baum,C., Schloter,M. and Schulz,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2022) Research Unit Comparative Microbiome
            Analysis, Helmholtz Zentrum Muenchen, Ingolstaedter Landstr.1,
            Neuherberg 85764, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2021
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1166.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022630575.1-RS_2024_03_24
            Annotation Date                   :: 03/24/2024 09:23:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,704
            CDSs (total)                      :: 5,549
            Genes (coding)                    :: 5,305
            CDSs (with protein)               :: 5,305
            Genes (RNA)                       :: 155
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 108
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 244
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 93 of 244
            Pseudo Genes (incomplete)         :: 175 of 244
            Pseudo Genes (internal stop)      :: 63 of 244
            Pseudo Genes (multiple problems)  :: 79 of 244
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3088261
            Orig. end                         :: 3111796
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP093291.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Research Unit Comparative
            Microbiome Analysis, German Research Center for Environmental
            Health, Ingolstaedter Landstr. 1 85764 Neuherberg.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23535
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="4"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23535
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23535
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13535](-)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13535)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            279..971
                     /locus_tag="MN093_RS16055"
                     /old_locus_tag="MN093_16055"
     CDS             279..971
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002027272.1"
                     /locus_tag="MN093_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16055"
                     /product="YukJ family protein"
                     /protein_id="WP_207391880.1"
                     /transl_table=11
                     /translation="MKEMPLKNYGVLKGTVVQSKIGKGKTPHYQVHLQGEAEVDYRIAI
                     NVKSQSYPSEVLYFASEHIDSEAIHILPTLPFGFTEVKNNEPKVALDYVRGNLFDSKQM
                     IPLPAEKSGSDNDLNEKIERYIKRAIDEKAIIYAFGERWGPEEKVPDAYFHFTPGNGIH
                     DIHMNQGNVEKWQGDDGKWQDGGILIHFEKKEEWIGIFLAFQSQSWCTDEEGHARVPVE
                     HCDYKRNN"
     gene            1131..1670
                     /locus_tag="MN093_RS16060"
                     /old_locus_tag="MN093_16060"
     CDS             1131..1670
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002186397.1"
                     /locus_tag="MN093_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16060"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_002202739.1"
                     /transl_table=11
                     /translation="MKITEENVVQQIKKRNEKSVTFIIQTYGGLLSVIIKRYVQSNQQD
                     YEECLDDVLLAIWFHIDSFDSSKNTFKQWIAAIAKYRAIDYQRKNARNQQQTVCTEIND
                     RLYQEQRKQNDFLDVQELLSELSATERNIFEKYYLEGVPSREIASHLNVKESWIHNKLS
                     RGRKKLKQIFIFKNGV"
     gene            1675..2646
                     /locus_tag="MN093_RS16065"
                     /old_locus_tag="MN093_16065"
     CDS             1675..2646
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029762.1"
                     /locus_tag="MN093_RS16065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16065"
                     /product="DUF4179 domain-containing protein"
                     /protein_id="WP_131246132.1"
                     /transl_table=11
                     /translation="MSIYKELNDIQLDITEFEETPLTKIEEKQWEKRVKNKLRKNKKTK
                     KWFGVAAACMLIVSITVPLGQTSLANMPFIAGLIEKYIDKQQPLDYSPYKTDIGKTAEN
                     KYGKLTLNEVLVDENKLFISSTFEPAKGVKFDYQTYLIPQVRINGRDFSNTKDAQSIEV
                     NDSMFTIYGGIELSEMPQTDELQIEITYDTFNRDTVIEQPWIFAIEVSQAQLMKEKRTF
                     DLNETIALYDGNKVTVNKVVSTPISTTIYYDVPQSTNEDIYFKIESESGEAHTFKEVVI
                     SNEDGGISFSRFDGINVAVGKYSLVPYSGKENKKIGPPIPIQ"
     gene            complement(2692..3525)
                     /locus_tag="MN093_RS16070"
                     /old_locus_tag="MN093_16070"
     CDS             complement(2692..3525)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397498.1"
                     /locus_tag="MN093_RS16070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16070"
                     /product="hypothetical protein"
                     /protein_id="WP_131246133.1"
                     /transl_table=11
                     /translation="MEFVNSIFQTLLTSVIQLFSLIGVIIVIGFILGYLESLTRTYWSR
                     AFGRKGFLLTAWIGVPVHELGHAIMCLVFRHKIIATQFFPTDTSQGALGYVQHQYNQKS
                     IYQRIGNFFIGIGPIISGITALIFLMRYFVPESYSLFNTTLETTIASTSINLDMIQNMF
                     LSTFFLLKSLFTMNNLLTPSFWLFLFIAICISAHIALSKPDIKGSIDGVIVMFIVLFLF
                     NIIAGLFQYDSNQLIGKMMKYNMYLIAFSSVALLFSCISTLVSFGFYKMRRGRSL"
     gene            3726..4508
                     /locus_tag="MN093_RS16075"
                     /old_locus_tag="MN093_16075"
     CDS             3726..4508
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158836.1"
                     /locus_tag="MN093_RS16075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16075"
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_131246134.1"
                     /transl_table=11
                     /translation="MKCPACNTENAAEARFCGNCGHSLTEEVVASGGQEEGQLSRPARV
                     KDTRPNETVEQVKQFASGYFQFFKNAFKSPSAIMESGNIEVRNGIVSLVLICFLGACIF
                     YRMMSAAATVTRTLVPDIATPTFFGESVMVFFFLLILTLFVGFIIFVSGKMMKSSFSFL
                     EAFGIWGTIATPAIAILVLSFLFSFLLIFFLPILLGLATTYMGISIIVAILKLDNGGVD
                     PVYTLIIANVLIGIATFIVFWSYIKTIIQTFIGGLTGF"
     gene            4528..>4872
                     /locus_tag="MN093_RS16080"
                     /old_locus_tag="MN093_16080"
                     /pseudo=""
     CDS             4528..>4872
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128956.1"
                     /locus_tag="MN093_RS16080"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16080"
                     /product="zinc-ribbon domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNVCTKCGAQYEDGVQFCQKCGMKRESLVVKKKMSGGTKVGITLL
                     TLLVIVIVGLYLYGSSYYKQTAQVDRMITILQERDGEKLAEIIKADDPAVIVTRESLTP
                     LFSYIKENPSY"
     misc_feature    complement(5184..5193)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            5208..6287
                     /locus_tag="MN093_RS16085"
                     /old_locus_tag="MN093_16085"
     CDS             5208..6287
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086311.1"
                     /locus_tag="MN093_RS16085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16085"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_113733622.1"
                     /transl_table=11
                     /translation="MSQTLTVKVKLIPTKEQIRLLEQSSHEYIKVINTLVSEMVKAKKS
                     TKKSTKDIEANIPSAVKNQAIKDAKSLFATKVKKSNYKIIPILKRPVCIWNNQNYSFDA
                     THISIPFKVNGKATRLKFRALLIDKNNRNLDLLKHKLGTLRITKKSNKWMAQISVMVPT
                     NERAGTKILGVDLGLKVPAVAITDDDKVRFFGNGRQNKYRKRKFRSVRKKLGKDKKVNA
                     IRRLDDKEQRWMQDKDHKISREIINFAIANHISVIRLEQLTNIRQTARTSRKNEKNLHT
                     WSFYRLSKFIEYKAILADIQVEYVNPAYTSQSCPKCAEKNKAQDRKYKCPCGFETHRDI
                     VGAMNIRYATVIDGNSQSA"
     gene            <6443..>6604
                     /locus_tag="MN093_RS16090"
                     /old_locus_tag="MN093_16090"
                     /pseudo=""
     CDS             6443..>6604
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016128956.1"
                     /locus_tag="MN093_RS16090"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="MN093_16090"
                     /product="zinc ribbon domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNELKEYLRQGEKRGDGIERTDFSLTKDGKYFFLFDRYKLKAKTY
                     YTTLLSNER"
     gene            6606..6716
                     /locus_tag="MN093_RS16095"
                     /old_locus_tag="MN093_16095"
     CDS             6606..6716
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024704.4"
                     /locus_tag="MN093_RS16095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16095"
                     /product="YARHG domain-containing protein"
                     /protein_id="WP_080118795.1"
                     /transl_table=11
                     /translation="MQAYFSKQSWYRENPYFTGKLTDIETYNVELIKSRE"
     gene            complement(6759..7181)
                     /locus_tag="MN093_RS16100"
                     /old_locus_tag="MN093_16100"
     CDS             complement(6759..7181)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332411.1"
                     /locus_tag="MN093_RS16100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16100"
                     /product="hypothetical protein"
                     /protein_id="WP_044437833.1"
                     /transl_table=11
                     /translation="MCAGLLAQTPEEPQEPKAAMPLDQEFSINATLYSARAWLSNDETF
                     AQTIWKGSRFASASHAGKSILPIGTVKILNLSDDTITVTASSEKDDTLKIVVPPRSEGV
                     LTSSALSDVQASTSGGASKVTFLFHIFFSRDPGPAK"
     gene            7381..8715
                     /locus_tag="MN093_RS16105"
                     /old_locus_tag="MN093_16105"
     CDS             7381..8715
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001110220.1"
                     /locus_tag="MN093_RS16105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16105"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_131246135.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.7e-63, bitscore:
                     210.4, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYVIIGGDAAGMSAAMQIVRNDETANVVTLEKGEIYSYAQCGLP
                     YVISGVIASTEKLIARDVKTFRDKYGIDAKVRHEVTKVDTEKKMVYAEHTETKDVFEFP
                     YDRLLIATGVRPVMPEWEGRDLQGIHLLKTIPDAERILKTLETNKVEAVTIIGGGAIGL
                     EMAETFVELGKKVRMIERNDHIGTIYDADMAEYIHKEADKHNIEILTNENVKAFKGNER
                     VEQIETDKGTYKTDLVLVSVGVQSNTDFLEGTNIRKTHKGAIEVNAYMQTNVKDVYAAG
                     DCATHYHVIKEIHDHIPLGTTANKQGRLAGLNMVDKRRAFKGTLGTGIIKFINLTLART
                     GLNEKEAKGLNIPYKTVKVDSTNMAGYYPSASPLHLKLLYHADTKQLLGGQVIGEEGVD
                     KRIDVIAMALFNKMSIHDLEDVDLSYAPPYNSVWDPIQQAARRAE"
     gene            8875..9285
                     /locus_tag="MN093_RS16110"
                     /old_locus_tag="MN093_16110"
     CDS             8875..9285
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996799.1"
                     /locus_tag="MN093_RS16110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16110"
                     /product="DUF3908 family protein"
                     /protein_id="WP_002030461.1"
                     /transl_table=11
                     /translation="MAINMNTIEEWIAESNARNEEDLGNVVEEMKEVCVGLDNATLIYT
                     KNVFCFGKKVEVFFFFQDHVVIGEEKEEYIEIEKLKYDDITNSNLKTNDKNTTLELKFS
                     NGKAINLDSLNDNYGTKNWLFARQIKSIFKVI"
     gene            complement(9318..9908)
                     /locus_tag="MN093_RS16115"
                     /old_locus_tag="MN093_16115"
     CDS             complement(9318..9908)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (48-149). E-value: 3e-15. Score:
                     47.1. Matches aSDomain: nrpspksdomains_MN093_RS16115_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002158829.1"
                     /locus_tag="MN093_RS16115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16115"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_044437838.1"
                     /transl_table=11
                     /translation="MSILQRLIEQAKNPRGTIGSSMLCIMNAAHTRLTNWALQKIHIRE
                     NAIILDIGCGGGKTIQTLSKRTPLGKIYGIDYSNQAVENSKKANMKDVKAAKVIIHQAS
                     VSSIPYHPDFFDLITAFQTHYFWPDVENDMKEVFRVLKPNGSFLLVAETFKIQYHMDKF
                     KTTEELVNLFYETGFTSVKCYEERGCLCLIGNK"
     aSDomain        complement(9462..9764)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MN093_RS16115_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.00E-15"
                     /label="MN093_RS16115_oMT.1"
                     /locus_tag="MN093_RS16115"
                     /protein_end="149"
                     /protein_start="48"
                     /score="47.1"
                     /tool="antismash"
                     /translation="ILDIGCGGGKTIQTLSKRTPLGKIYGIDYSNQAVENSKKANMKDV
                     KAAKVIIHQASVSSIPYHPDFFDLITAFQTHYFWPDVENDMKEVFRVLKPNGSFLL"
     gene            complement(10001..11563)
                     /locus_tag="MN093_RS16120"
                     /old_locus_tag="MN093_16120"
     CDS             complement(10001..11563)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002135039.1"
                     /locus_tag="MN093_RS16120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16120"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_215576891.1"
                     /sec_met_domain="PF00881 (E-value: 9e-10, bitscore: 37.1,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPDTFLHHLHFSINEIMSSDKEIDWEDAPLPYKLYRNLPVIPLS
                     LEIPLTLRNSSTKPNLEEIGHYLWYSFGLTQLCQPTTNLENNKTTTLFRRFIPSGGALY
                     PNELYMYLKIDHYPDGIYHYDAAHHRLILLREGNFDSYLTEALGNRCNVHSCFGAAFVS
                     TMFWKNFFKYNNFSYRLQGLDSGVLIGQLLECAKQFGYTNGVYFQFLDRAMNHLLGLSE
                     GEESVYAVIPLSTEPNTDWFHDDHHENKTITSHDLLQQIPPLTHEHFVRSKYVDEYPMI
                     KKINAASMIESTEHFQTFTREERQQYSAHAVQLPKVERLSYDFLQLCKKRYSPDSDFIL
                     TKWDAAELATLLQAASLSFPYYNDLDGKYLNENARVSLYGCFYNVKDIENGAYAYNSRT
                     HSIQPIRYGDLRYSLQSSMTMDNVNLFQVPLCLHVIGNKDYYKNKLGYRGYRIHQMEAG
                     MLVHKLVLAATAMGMGGHPLLSFDTNSCDQLYGIDAGNETSLIQIPVGAYRARNWLKGS
                     LHN"
     gene            complement(11586..13535)
                     /locus_tag="MN093_RS16125"
                     /old_locus_tag="MN093_16125"
     CDS             complement(11586..13535)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191877.1"
                     /locus_tag="MN093_RS16125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16125"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_215576892.1"
                     /sec_met_domain="YcaO (E-value: 6.8e-84, bitscore: 280.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 3.3e-139, bitscore:
                     462.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNILLIGDGLLTDYVHEQLCKQYSLIRQHTITEALPENIHLAL
                     VLHDGSPSSVHRDAELIFRSNNIPWLRAFTSFGEGIIGPYVKPLTTGCSHCADGRRFIA
                     GFDQKEMWELQRKYALKAENVTRRDVRATQNGMLQMCQLIHAETEKILAHGYSSLENEL
                     ILLDLQTLQCTRNSFLPDPLCPVCSNLPDDTADAAQISLQPSLKTSTETYRCRSIHELN
                     TFLTRDYLDYRTGILNGKMQHSLLPFADVIINMPLLFGNEGVAGRTHSFSLSEATAILE
                     GLERYCGMSPRGKKTNVHGSFRELEDIALNPLTLGVHTNEHYNRDSFPFKPFDPDYEQN
                     WVWGYSLLQSRPLLVPESIAYYSLGHRDAFVYETSNGCAIGGSLEEAIFHGILEIVERD
                     AFLLTWYAELPLPRLDLSSANDTELQLMLERLRTITGYELYVFNATMEHGIPSIWVIAK
                     NTRKDGMNLVCAGGAHMEPIRAVKNAIHEIAGMLLITDEELEQKREKYENCLQDPYLVS
                     QMEDHSMLYGLKEAEERLHFLLRDDAPVQTFQEMNALQSFDMDLTSDLHQLLNRLHQSG
                     LEVIVVDQTVPLIEKNGLHCVKVIIPGMLPMTFGHHLTRVTGLDRVYTVPMTLGYWAEP
                     LTNESLNPHPHPFP"
     gene            complement(13532..15451)
                     /locus_tag="MN093_RS16130"
                     /old_locus_tag="MN093_16130"
     CDS             complement(13532..15451)
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0003674 - molecular_function [Evidence
                     IEA]"
                     /GO_process="GO:0030152 - bacteriocin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03693"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016513905.1"
                     /locus_tag="MN093_RS16130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16130"
                     /product="putative thiazole-containing bacteriocin
                     maturation protein"
                     /protein_id="WP_215576893.1"
                     /sec_met_domain="TIGR03693 (E-value: 0.0, bitscore: 1164.3,
                     seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     3e-55, bitscore: 182.5, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 3.5e-11,
                     bitscore: 41.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLPVHAKLKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDW
                     IEKLMPMFNGNHSLTEITDGLPLPYQNRVFEIGEILYENGFVRDVSQDAPHELNSALLD
                     RYASQIEFLEADSHSGALKFETYRAANVLIIGSGDMLTSLVSSLLESGLPTFHYLVTDR
                     AETNYDRIHELSERAYANDDNVLIQEIDITIDRPLHEVFEPFDWILYVSQNGDIESLRA
                     IHTICREFKKNFIPAICLSRIGLAGPVVTVDREECWESAWHRLHETTLQSENPPEPFSP
                     IASAMLANVIVFELFKHVAEDSHRQHNPQFFLLNLETLEGKWHPFIKHLLATDEIFTID
                     TVQNLQENLAQRSGQYTSTELFRFFDTLTSKEAGIFHMWDEQDLNQLPLSQCNIQVANP
                     LSDGPTSPLPTITCGGLTHNEARREAGLTGVETYVAEMIHRLIPEHTDIGIGAGETMTE
                     GVYRALQKHLNNKLYERQSHMLEEITELYLTEIHDKHCRFYYDALSTIHEIPKVGMSEE
                     LLGFPVVWIGINDRWYGAVNINITLALRNALQQALLHIQNEEIPYKANMLPESSIVLYS
                     TDPVRVAIQEEEEIPGVQSLQVALQNLTENNLYPFVFDLAIESFLRDNLDGVYGVLIAK
                     EDDQ"
     aSDomain        complement(15152..15451)
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MN093_RS16130_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="1.60E-57"
                     /identifier="RREFam011.1"
                     /label="MN093_RS16130"
                     /locus_tag="MN093_RS16130"
                     /protein_end="100"
                     /protein_start="0"
                     /score="182.5"
                     /tool="antismash"
                     /translation="MNNLPVHAKLKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDW
                     IEKLMPMFNGNHSLTEITDGLPLPYQNRVFEIGEILYENGFVRDVSQDAPHELNS"
     aSDomain        complement(15185..15424)
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MN093_RS16130_Thiopeptide_F_RRE.1"
                     /evalue="1.80E-13"
                     /identifier="RREFam004.1"
                     /label="MN093_RS16130"
                     /locus_tag="MN093_RS16130"
                     /protein_end="89"
                     /protein_start="9"
                     /score="41.2"
                     /tool="antismash"
                     /translation="LKANKDTFFLPDSNGGVYFRNNSSSFRMDGDGIYDWIEKLMPMFN
                     GNHSLTEITDGLPLPYQNRVFEIGEILYENGFVRD"
     gene            complement(15577..16833)
                     /gene="odhB"
                     /locus_tag="MN093_RS16135"
                     /old_locus_tag="MN093_16135"
     CDS             complement(15577..16833)
                     /EC_number="2.3.1.61"
                     /GO_component="GO:0045252 - oxoglutarate dehydrogenase
                     complex [Evidence IEA]"
                     /GO_function="GO:0004149 - dihydrolipoyllysine-residue
                     succinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="odhB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016716916.1"
                     /locus_tag="MN093_RS16135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16135"
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="WP_060751877.1"
                     /transl_table=11
                     /translation="MIEIKVPELAESISEGTISQWLINVGDKVEKGGSVVELETDKVNV
                     EIIAEDSGIVSKLLGEPGDTVEVGATIAILDANGAAVAVSTPAPLAEQPKQETTEAPKA
                     AAPSAEQNKALQGLPNTNRPIASPAARKMARELGIDLNEVRSTDPLGRVRPHDVQAHAA
                     APKEAPAAPKQSPAPVAKTEFEKPVERVKMSRRRQTIAKRLVEVQQTSAMLTTFNEVDM
                     SAIMELRKERKDAFEKKHDVRLGFMSFFTKAVVAALKQFPLLNAEIQGDELIIKKFYDI
                     GIAVAAPDGLVVPVVRDANQLNFAEIESEIRNLGLKARDNKLSLKELQGGTFTITNGGV
                     FGSLMSTPILNSPQVGILGMHKIQVRPVAIDAERMENRPMMYLALSYDHRIVDGKEAVS
                     FLVAVKDMLEDPKSLLLEG"
     gene            complement(16963..19830)
                     /gene="odhA"
                     /locus_tag="MN093_RS16140"
                     /old_locus_tag="MN093_16140"
     CDS             complement(16963..19830)
                     /EC_number="1.2.4.2"
                     /codon_start=1
                     /gene="odhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000197121.1"
                     /locus_tag="MN093_RS16140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16140"
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="WP_002186381.1"
                     /transl_table=11
                     /translation="MTRKNTTTNPWAKFHGPNLGYVIEQYDLYVTGAGSVDPELQELFE
                     IFGAPSFQDDVVTGDNTATHFSPQNTGNIEKILKVVQLVEQIRSFGHTLAHINPMEDAA
                     NGQSLIEKTMNELSDADLKAIPAKTVWQDAPEGIHTALDVIHRLKDVYTKSLAYEFSHI
                     QDSEERAWLHQMVESNSLRQPLSNKKRTALLKRLAAVEGFEQFLHKTFVGQKRFSIEGV
                     DMLVPVLDEIVSEGAKGGVEDVMIGMAHRGRLSVLAHVLEKPYNHMFAEFKHAKIEGAV
                     ANAGWTGDVKYHLGREQVVGNEEVSTRVTLANNPSHLEFVNPVVEGFARAAQENRKKSG
                     LPEQDTTKSFVILVHGDAAFPGQGVVSETLNLSRLNAYQTGGTIHVIANNAVGFTTDSY
                     DSRSTKYSSDLAKGFDIPIVHVNADDPEACLAAANLAIQYRTLFKKDFLIDLIGYRRYG
                     HNEMDDPAVTQPQVYKKIKNHPTVRAIYADQLQSAGVLNADEVETITQFIQEELKAEYA
                     QVPPADTSAATIHVKVPEVVAKGIQPIDTGVSIESLRAINEGLLSWPEGFNVYPKVKKI
                     LERRKDALEENGKIEWALAESLAFASILQEGTPIRLTGQDSQRGTFAHRHIVLHDTDTN
                     ETYSPLHRLPNINASFSVHNSPLSEAAVVGYEYGYNVFAPETLVMWEAQYGDFSNTAQA
                     LFDQYVSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQLAAENNWTVANLTSA
                     AQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTASQLSEGRFQPALEQENLGA
                     KPNKVKRLVLSTGKMAIDLAAEIESGKHEYSLDEVHMVRIEQLYPFPAEKVQSIIKRFK
                     NLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQE
                     LIVAHALDVKYNFRQDKQEIEVFSN"
     misc_feature    20478..20498
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 30.06"
                     /tool="antismash"
     misc_feature    20530..20544
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 22.18"
                     /tool="antismash"
     gene            20657..20872
                     /locus_tag="MN093_RS16145"
                     /old_locus_tag="MN093_16145"
     CDS             20657..20872
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428504.1"
                     /locus_tag="MN093_RS16145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16145"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_000428507.1"
                     /transl_table=11
                     /translation="MENKMVEYRKKFGLSQEKLAEKLGVSRQTIISIEKGKYDPSLPLA
                     FEIAKTFQTTIEHVFIYEGKEEGEKG"
     gene            20869..21246
                     /locus_tag="MN093_RS16150"
                     /old_locus_tag="MN093_16150"
     CDS             20869..21246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016101524.1"
                     /locus_tag="MN093_RS16150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16150"
                     /product="permease"
                     /protein_id="WP_215576894.1"
                     /transl_table=11
                     /translation="MNYSQKYFVIMGIIFLFMSGFMILTGIMTHSAPPAPTYTLLAMMI
                     MCFCLSYLHPQFKEKDERMKLIRYKGMFFSFFALTAYYLLFSIGLNLKVITLSAVELLN
                     ILMALTMSTVFISFVVLSKRY"
     gene            21275..21457
                     /locus_tag="MN093_RS16155"
                     /old_locus_tag="MN093_16155"
     CDS             21275..21457
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002086895.1"
                     /locus_tag="MN093_RS16155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16155"
                     /product="DUF3976 domain-containing protein"
                     /protein_id="WP_215576895.1"
                     /transl_table=11
                     /translation="MQMMYAFGMGLVLFLAVFLFIRKDIQGGTLTKRGFYKMIGCLVVM
                     FIAIIVMIVLINKTL"
     gene            21594..21940
                     /locus_tag="MN093_RS16160"
                     /old_locus_tag="MN093_16160"
                     /pseudo=""
     CDS             21594..21940
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034130.1"
                     /locus_tag="MN093_RS16160"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="MN093_16160"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNKKAIFFIAICLLLI"
     gene            21980..22525
                     /locus_tag="MN093_RS16165"
                     /old_locus_tag="MN093_16165"
     CDS             21980..22525
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002168863.1"
                     /locus_tag="MN093_RS16165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16165"
                     /product="hypothetical protein"
                     /protein_id="WP_215576897.1"
                     /transl_table=11
                     /translation="MRWKAGTFEKIETNDSSIEQLINTFKKQNLNGGAVISCFKVHNEN
                     FFKEIPYEIDRYEHFFKKVFNSLDIINNLEELKIHTSEKYKFQFKYNSAVILDGSIAFQ
                     IIRGGAYKYFPERMVVAKQLASDVCQYMFQDRYEDIIVFESQSPWTDWFYDVAWDNTWM
                     VLDSKEHKMWLVCATDTD"
     gene            22685..23281
                     /locus_tag="MN093_RS16170"
                     /old_locus_tag="MN093_16170"
     CDS             22685..23281
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002126039.1"
                     /locus_tag="MN093_RS16170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_16170"
                     /product="hypothetical protein"
                     /protein_id="WP_002126039.1"
                     /transl_table=11
                     /translation="MKKIQKLLLLMMVVGLTVGVLAGCANPKDTTEEFLTAIQKGDVEK
                     ARTFVESDKEFNKLNEKTDDAEAKAMLSAITKNFKFEKPEEVSKKDDKAEVKVKITSAD
                     LSVAVTKAVGEVMPMAFASAFSEDKEQSEKAIEKTMTSTIVKNLADKDAAMATREVTLN
                     LKKNKDGDYKIVADDNLKEVLFANAKSLEKMFGGK"
     tRNA            complement(23372..23444)
                     /anticodon=(pos:complement(3111670..3111672),aa:Val,
                     seq:gac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MN093_RS16175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MN093_16175"
                     /product="tRNA-Val"
     gene            complement(23372..23444)
                     /locus_tag="MN093_RS16175"
                     /old_locus_tag="MN093_16175"
ORIGIN
        1 atatgtcaca acactccaaa acaccgcatc atcagtagcc acaatcgctt gtccatcacg
       61 gattacacta ggcgcgtatt tatgtaatat cccgtatcgt gaaaatgaac tattaaagaa
      121 gacgacgtta atgatttttg gtgcggtgtt gcttgtagtg gtggaggtta ttgtttggta
      181 tatgttgaga aaataagaaa tcctcctggg aaaggaggat tttcttttta tatggataat
      241 gcctaaagta tgaacagctt ctactaaatg aataggagat gaaagagatg cccttaaaaa
      301 actacggtgt attaaaaggt acagttgtac aatctaagat tggaaaaggg aaaacacctc
      361 attatcaagt tcatttacaa ggcgaagcag aagtagatta tcgtattgca attaacgtaa
      421 agtcgcaaag ttatccgtca gaagttttat attttgcaag cgaacatatt gattcagaag
      481 ctattcacat tttaccaaca ttaccgtttg ggtttacaga agtgaaaaac aatgagccga
      541 aagtagcttt agattatgta agaggtaatt tatttgattc aaagcaaatg attcctttac
      601 ctgctgaaaa atcgggatct gataatgatt taaatgagaa aatagaacgt tatataaaac
      661 gagcaataga tgagaaagca attatttacg cgtttggtga aagatgggga ccagaagaaa
      721 aggttccgga tgcgtatttt cattttacac ctggaaacgg tatacacgat attcatatga
      781 atcaagggaa tgtagagaaa tggcaaggtg atgatggcaa atggcaagac ggtgggatat
      841 tgattcactt tgagaagaag gaagagtgga ttggtatttt tcttgccttt cagtcacagt
      901 catggtgtac ggatgaagaa gggcatgctc gtgtgccggt tgagcattgt gattataaga
      961 gaaataactg atgagaagag ctagttcaaa atggactagc tcttctcatt gtatacaaga
     1021 tatatagtga tgaaattatg tttgtaatat taaaaaatgg tgatagggtt attgattttt
     1081 attcgtatta gaaagtaggt acccaattag caggacaagg aggtctacct ttgaagataa
     1141 cggaagaaaa tgttgtgcaa caaattaaaa agcgtaatga gaaaagcgtt acgtttatta
     1201 ttcaaacata cggcggttta ctaagcgtga ttattaaaag atatgtacag agtaatcagc
     1261 aagattatga agaatgctta gatgatgtat tattagccat ttggtttcat atcgattcat
     1321 ttgattcaag taaaaatacg tttaaacaat ggatagcagc cattgctaaa tatcgggcaa
     1381 ttgattatca gcggaaaaat gcgagaaatc agcaacaaac tgtctgtaca gagattaatg
     1441 atcgtctgta tcaagaacaa agaaaacaaa atgacttctt agacgtacag gaattgctta
     1501 gtgagttgtc agcaacagag cggaacattt ttgaaaagta ttatttagaa ggtgtaccgt
     1561 ctcgtgaaat tgcttcccat cttaacgtga aagaatcatg gattcataac aaactgtcac
     1621 gcggacgaaa aaagctcaaa cagattttta tttttaaaaa tggagtgtga gggcatgtct
     1681 atttataaag agttaaatga tattcagcta gatatcacag agtttgagga gactccctta
     1741 accaaaatag aggaaaagca gtgggaaaaa cgtgtgaaaa ataagctacg caaaaataaa
     1801 aaaacaaaaa aatggttcgg ggtcgcagca gcttgcatgt taattgtcag tattacagtg
     1861 ccacttggac aaacatcttt agcaaatatg ccatttattg cgggattgat tgaaaaatat
     1921 attgataaac agcaaccact tgactattct ccctataaaa cggatattgg aaaaactgct
     1981 gaaaataaat acggtaaact gacgttaaat gaggtattag tggatgaaaa taaattattc
     2041 atcagttcaa catttgagcc agcgaagggt gtgaaatttg attatcaaac atatttaatt
     2101 ccacaggtac gaataaatgg gcgtgacttt tctaatacaa aggatgcaca atcaattgaa
     2161 gtaaatgatt ctatgtttac aatttacggt ggtatcgagt taagtgaaat gccacaaact
     2221 gatgaacttc aaatcgaaat tacttatgat acattcaaca gggatactgt aattgagcaa
     2281 ccatggatat ttgctattga agtatcacaa gctcagttga tgaaagagaa gcggacgttt
     2341 gatttaaatg aaacaattgc tttatacgat ggcaataaag taactgttaa caaagtagtt
     2401 tctacgccga tttccacaac gatttattat gatgtgccac aaagtacaaa tgaagatatt
     2461 tattttaaaa tcgaatcaga atctggggaa gcacatacat ttaaagaggt ggttatatcg
     2521 aatgaagatg gcggtatttc ttttagtaga tttgatggaa taaatgtagc ggtgggaaaa
     2581 tattcacttg taccgtattc ggggaaagaa aacaaaaaaa ttggaccacc tattccgatt
     2641 caataactta ttaaagctga taaataatta tttaaggaga gaagaggacg ttcacaatga
     2701 acgccctctt ctcattttat aaaacccaaa actaacaagt gtagaaatac aagagaaaag
     2761 aagcgctaca ctagaaaacg cgatgagata catattatat ttcatcattt taccgattag
     2821 ttgattacta tcgtactgaa acagtcccgc tattatattg aataaaaata atacgataaa
     2881 catgacgatg acgccgtcta ttgatccttt aatgtctggt ttacttaaag cgatatgtgc
     2941 ggaaatacaa atagcgataa ataaaaataa ccaaaaagaa ggggtcaata aattgttcat
     3001 tgtaaacaag ctttttaata aaaagaatgt tgataaaaac atgttttgga tcatgtctaa
     3061 gttaatagaa gtcgatgcga ttgttgtttc gagagttgta ttaaataaag aatatgactc
     3121 tggtacgaaa tagcgcatta aaaatattaa tgcagtaata ccagaaataa taggaccgat
     3181 gccgataaag aaattaccga ttcgttggta tatacttttt tgattgtatt gatgttgtac
     3241 gtaacctaaa gctccctgac ttgtatctgt cgggaagaac tgcgttgcta taattttatg
     3301 gcggaatact agacacataa ttgcatgccc aagttcatga acgggaacac caatccatgc
     3361 ggttaaaaga aaacctttcc taccaaaagc tctcgaccaa tacgttcgtg tgagagattc
     3421 taaataacct aatataaatc caattacaat gatgacacca attaaagaaa ataattggat
     3481 cacacttgta aggagtgttt gaaaaatcga gtttacaaat tccactgtct tcatccaatc
     3541 tgtttaaagt ttcactttat ttgctctgtt tcataataac attatttttc tatattacta
     3601 gcacacatag tttcgtttaa aagaaggatt tcatattctt tttcttgtag tcatgtttta
     3661 tgtacaaagt catatattga atttgtaaca ccctataagg tatatgctta aggagggatg
     3721 agagaatgaa atgtccggca tgtaatactg aaaatgcagc ggaagcaagg ttttgcggaa
     3781 attgtggaca ttcgttaacg gaagaagtgg tagcgagtgg tggccaggaa gaagggcagc
     3841 tatcgcgccc ggcacgagta aaggatactc gtccgaatga aacggtagag caagtgaaac
     3901 aatttgcaag tggctatttt cagttcttta aaaatgcttt taaatcacca tcggccatta
     3961 tggaaagtgg aaatattgaa gtgcgaaatg gaattgtaag tcttgtgctt atttgctttt
     4021 taggagcatg tattttttat agaatgatga gcgcagcggc gactgttacg aggacattag
     4081 tgccagatat agctactcct actttctttg gagaatctgt aatggtcttt ttctttttat
     4141 taattttaac tttatttgtc ggatttatta tttttgtaag tggtaagatg atgaaatcat
     4201 ctttttcttt tcttgaagca ttcggtatat gggggacgat agcgacgcca gctattgcta
     4261 tactagttct ttcttttcta tttagtttcc tattgatctt ttttttacca atcttattag
     4321 ggctggctac aacgtatatg ggaattagta taattgtagc tatattaaaa ctagacaacg
     4381 gcggagtaga tcctgtttac acacttatta tcgcaaatgt tttaatcgga attgcaacgt
     4441 ttatcgtgtt ttggtcttac attaaaacga taatccaaac ctttatcggg ggattaacag
     4501 gcttctaacg aaaaggtggt tgaatggatg aatgtatgta caaaatgcgg agctcagtat
     4561 gaagatggag tgcaattttg ccaaaaatgc gggatgaaga gggaaagtct tgtagtaaag
     4621 aagaaaatga gcggcggtac aaaagttggc attacactct taacattact tgttatagta
     4681 attgttggat tgtatttgta tggatcatcg tattataagc agacggcaca agtagaccga
     4741 atgattacta ttttacaaga gagggacggg gagaaattag ctgagatcat caaggcagat
     4801 gatccagccg ttattgtaac gagagagagt ttaacgcctc tattttcata tataaaagaa
     4861 aatccatctt acagcccttt ccgaacgaga aagcccattg cctttaggca tgggatgaaa
     4921 gtgaggttgg atacggagta ccactaaaaa tcgcaaggtt cgtggtactt taagtatcca
     4981 aagtataggt agtttcttcg agtctttttg ttgtaatttt tcgaaagtaa atgatacagt
     5041 gtaactagaa tcaatgatga tagcagtacg tttcaaagtg tttgagagga aaatctcctc
     5101 acctcatgta gttgtaaagt ttatggacac gttctcattt tgtttctatt gctagaaatg
     5161 tatcaaatgc acgatgttga aaatcaaaaa acaaggggat gaaacgcatg tcacagaccc
     5221 taacagtgaa agtgaaattg attccaacaa aagagcaaat ccgtttatta gaacaaagta
     5281 gtcatgaata tatcaaagtt ataaatacac ttgtatcgga aatggttaaa gcaaagaaaa
     5341 gtacgaaaaa aagcacaaaa gatattgaag caaatatccc aagtgcggtg aagaatcaag
     5401 caatcaaaga cgcgaaaagt ttgtttgcta caaaagtaaa gaaaagcaat tataaaatca
     5461 ttccgatttt aaagaggcct gtttgtatat ggaacaatca aaattattcg tttgacgcca
     5521 ctcatatttc aatcccgttt aaggtaaatg gaaaggccac tcgtttaaag ttccgagctt
     5581 tattaatcga taaaaacaat cgcaatttgg atttgctaaa acataagtta ggtacacttc
     5641 gcatcacaaa gaaatcgaat aagtggatgg cccaaatatc tgtcatggtt cctacaaatg
     5701 aaagagcagg gacgaaaatt ttaggagtag acctaggcct caaagtccct gcggtagcga
     5761 ttacagatga tgacaaggtt cgtttctttg gaaatggtag gcaaaacaaa tataggaagc
     5821 gtaagtttcg tagtgtgcgt aagaagttag gaaaagacaa aaaagtgaat gcgattcggc
     5881 gattggatga taaagaacaa agatggatgc aagataaaga tcataaaata agtcgtgaaa
     5941 tcattaattt tgcgattgca aatcatattt ctgtcattcg attagaacaa ttaacgaata
     6001 taagacagac ggcaagaaca agccgtaaaa acgaaaaaaa cctacacact tggtcattct
     6061 atcgtttgtc aaaatttatt gaatataaag cgatattagc tgatattcag gttgaatatg
     6121 tgaatccggc ttatacaagt caaagctgtc caaaatgtgc tgaaaagaat aaggcgcaag
     6181 acagaaaata caagtgtcca tgtggatttg agacacatcg tgatatcgtt ggggcgatga
     6241 atattcgcta tgcaactgtg attgatggta acagtcaatc agcctaagca cctatatggt
     6301 ctggtttagg aggggcaatg agatgccctc atcttgaagg ctgttcaaaa cagaaatgga
     6361 ctgcgaacgc ttagtcattc aagaatccca cccgtaattc cataaggatt cgggcttgcg
     6421 actttagtcg tgggagtctc aagtgaatga attgaaagaa tatttgaggc aaggtgaaaa
     6481 acgaggggac ggaatcgaaa gaacagattt ttcgttaacg aaagacggga agtatttctt
     6541 tttatttgat cggtataaat tgaaagcgaa gacgtattat acgacgttgc tttcaaacga
     6601 aagatatgca agcgtatttt tcaaaacagt cttggtatag agaaaatccg tattttacag
     6661 gaaagctaac agatattgaa acttataatg ttgaattgat caaatcaaga gaataaacac
     6721 gtgaaaaagg tacagtgcat aactgtaccc ttttatggtt atttagctgg accaggatcc
     6781 cttgagaaaa agatatgaaa gaggaatgtg actttgcttg ctcctcctga tgtacttgct
     6841 tgcacatcag ataatgcact agatgttaaa acaccttcag aacgaggggg tacgactatt
     6901 ttgagagtat catctttttc tgatgatgca gtaactgtta ttgtatcatc agataagttc
     6961 aaaattttaa cagtaccgat tggtaagatg gacttgccag cgtgtgatgc tgaagcaaag
     7021 cgagagcctt tccaaatcgt ttgtgcgaaa gtctcatcat tagataacca agcacgagcg
     7081 ctgtataatg ttgcgttaat agaaaattct tgatcaagtg gcatggcggc tttcggttct
     7141 tgcggttcct ctggagtttg agcgagaagg ccggcgcaca tgtatgtttc acctactttc
     7201 aatagttgct gttatagcat attaaatatg ttgtttataa gacacgacgg atacctattc
     7261 atgcataggt ttgtgcacca aatttgtaga tagaattcta tttctttaca atggaagtag
     7321 gtgttatttc tataaaatat ggaaatcgta aagagtatgt aaaaaagaag gagtggtaaa
     7381 gtgaactatg tcattattgg cggagatgca gcaggtatga gtgcagcaat gcaaattgtt
     7441 agaaacgatg aaacggcaaa tgttgtaacg ttagaaaaag gtgaaatcta ttcatacgct
     7501 cagtgcggat taccgtatgt gattagtggt gttattgctt ctactgaaaa gttaattgca
     7561 cgcgatgtaa agacgtttcg tgataaatat ggaattgatg cgaaagtacg tcatgaagta
     7621 acgaaagtag atacggaaaa gaaaatggtg tacgcagagc atacggagac gaaagatgtt
     7681 tttgaatttc cgtatgaccg tttattaatt gcgactggag tgcgtcctgt tatgccagaa
     7741 tgggaagggc gagatttgca aggcattcat cttttaaaaa caattccgga tgctgagcgc
     7801 atattaaaaa cgctagaaac gaataaagtt gaggctgtaa cgattattgg cggcggtgca
     7861 attggtctag agatggcaga aacattcgtc gaacttggta agaaagtaag aatgattgag
     7921 cgaaatgatc atatcggtac gatttatgat gcagatatgg ctgaatatat acataaagaa
     7981 gcagataaac acaatattga aattttaacg aatgaaaatg tgaaagcatt taaaggaaat
     8041 gaaagagtgg aacaaattga aacggataaa ggtacgtata aaacagatct cgttttagta
     8101 tctgtcggtg tacagtcaaa tactgatttt cttgaaggga caaatatacg taaaactcat
     8161 aaaggtgcaa ttgaagtaaa tgcttatatg caaacaaatg tgaaagacgt atacgctgct
     8221 ggtgattgtg caacacatta ccatgttata aaggaaatcc atgatcatat cccgctggga
     8281 acgactgcga ataaacaagg gcgacttgcc ggactcaata tggttgataa acgaagagca
     8341 ttcaaaggta cgttaggtac aggcattatt aaatttataa atctgacgct cgcaagaaca
     8401 ggcttaaatg aaaaagaagc gaaagggcta aacatcccgt ataagacggt caaagtagat
     8461 tcaacaaata tggcgggcta ttacccaagt gcttcgccac ttcacttgaa attactatat
     8521 cacgccgata cgaaacaatt attaggcgga caagtaattg gagaagaagg tgtagataaa
     8581 cgtattgatg ttatcgcaat ggcacttttc aataaaatga gtattcacga tttagaagat
     8641 gtcgacttaa gttacgcacc accatataac agcgtttggg atccaattca acaagcagca
     8701 aggcgagcgg aatagcactt ttttaagtgc tatttttttt gtgaaagggg aataaataaa
     8761 gtttcacttt attttgaata taccgttcac ccttgaaaac atagtacgta tcgcttatat
     8821 tgtcatatag tatttatttt tttataaagc aatgaacgaa ccagggggca cagtatggca
     8881 attaacatga atacaatcga agaatggatt gctgaatcaa atgcaagaaa cgaagaagac
     8941 ttaggaaacg ttgttgaaga gatgaaagaa gtatgtgtcg gacttgataa cgcgacatta
     9001 atttatacga aaaacgtatt ttgtttcggt aagaaagtag aagtattctt cttcttccaa
     9061 gatcacgtcg ttatcggaga agagaaggaa gagtatattg agattgaaaa attaaagtat
     9121 gatgacatta caaatagcaa cttaaaaaca aatgacaaaa atacaacgtt agaactaaag
     9181 ttttctaacg ggaaagctat taatttagat agtctaaatg ataactacgg tacgaaaaac
     9241 tggttatttg caagacaaat taagagtatt tttaaagtaa tctagtaaaa aaggcagacc
     9301 ttgaaaggtc tgctttttta cttatttcct attaaacaaa ggcaccctct ttcttcgtaa
     9361 catttcacgc ttgtaaatcc cgtctcataa aaaaggttta ctaattcttc ggtcgtctta
     9421 aatttatcca tatgatattg gattttgaaa gtttcagcga ctagtaaaaa ggatccattc
     9481 ggttttaaga cgcgaaatac ttctttcata tcattctcaa catcaggcca aaagtagtgg
     9541 gtttgaaaag cggtaatgag atcaaagaag tccggatgat atggaataga ggagacgctt
     9601 gcttgatgaa taattacttt cgctgctttg acatccttca tatttgcttt ctttgagttt
     9661 tcaacagctt gattggagta gtcgatcccg tatattttcc caagtggagt tcgttttgaa
     9721 agagtctgta tggttttacc acccccacaa ccaatatcta aaataattgc attttcacgt
     9781 atatgtattt tttgtaaagc ccaatttgtt agtctcgtat gcgcagcatt cataatgcaa
     9841 agcatagagg aaccaattgt cccgcgagga tttttcgctt gctcgattaa tctttgtaaa
     9901 atactcaatt caaactctcc ttttatataa gaatatgtat ttatttcgct tttaataatt
     9961 taactccttt aaaaaaagca cgccattaat cggcgtgctt ctaattatgc aaggaccctt
    10021 ttagccaatt tcgcgctcga tacgccccaa ccggaatttg aatgagtgaa gtttcatttc
    10081 cggcatcaat cccgtacaat tgatcgcatg aatttgtatc aaaacttagt aacggatgcc
    10141 cgcccatccc catagcggtc gcagctaaaa cgagtttatg aacgagcatg ccagcttcca
    10201 tttgatgaat gcgatatcct ctataaccta atttattttt atagtaatct ttatttccga
    10261 ttacatgtag acaaagtggt acttgaaaaa gatttacgtt atccatcgtc atactagatt
    10321 gcagagaata acgaagatct ccgtaccgaa ttggctgtat ggaatgtgtc ctactgttat
    10381 aagcgtaagc gccgttttct atgtctttta cgttataaaa acatccatat agtgagactc
    10441 gtgcgttttc atttaaatat ttgccatcaa ggtcgttgta ataagggaag gagaggctcg
    10501 ctgcttgtag tagagtagca agctcggctg catcccattt cgttaaaatg aagtcagaat
    10561 caggtgaata tcgtttttta caaagttgta aaaaatcata tgataaacgt tccactttag
    10621 gtagctgtac agcgtgtgca ctatattgtt gtcgttcttc acgggtaaat gtttggaagt
    10681 gttctgttga ttcaatcata gaagctgcgt ttattttttt tatcatcgga tattcatcta
    10741 catattttga gcgaacgaaa tgctcatgtg ttaacggcgg gatttgctgc aacaagtcat
    10801 gagaagtaat agttttattt tcgtgatgat catcatgaaa ccaatctgta ttcggttctg
    10861 tacttaaagg aataacagca tacacacttt cttcaccttc tgacagtcca agtaaatgat
    10921 tcattgcccg atctagaaac tgaaaatata caccatttgt ataaccaaat tgttttgcgc
    10981 attcaagtaa ttgaccgatt agaacaccgc tatctaatcc ttgaagacga tacgaaaagt
    11041 tattgtattt aaagaagttt ttccaaaaca tagtggatac aaatgcagca ccaaaacaag
    11101 aatgtacgtt acaacgattg ccgagtgctt ctgtaagata agaatcgaaa tttccttcgc
    11161 gaagtaagat aagacggtga tgcgcggcgt cgtaatggta aatgccgtct ggataatgat
    11221 caatttttaa atacatatat aattcattcg gatataaagc acccccagaa gggatgaatc
    11281 ttcgaaatag agtcgttgtt ttattatttt ctaggttagt agtaggctga cataattgtg
    11341 ttaaaccaaa tgagtaccaa agataatgac cgatttcctc taagttaggt ttagtagaag
    11401 aattccgcaa agttaatggg atttctaaag agagagggat tactggtaaa tttcgatata
    11461 atttataagg aagtggtgcg tcttcccagt caatctcctt atcggacgac ataatttcat
    11521 taatagaaaa atggagatga tgtaaaaaag tatcaggttg catcaaattt ccccctcact
    11581 atgaattatg gaaacggatg cggatgtgga tttaaacttt cattcgttaa aggctcagcc
    11641 caatatccaa gtgtcatcgg tacggtatac actctatcca gtcctgtaac ccgagtgaga
    11701 tggtgaccga acgtcatcgg taacatgcct ggaataatta cttttacaca atgtaagccg
    11761 ttcttttcta taagggggac cgtttgatct acaacaatta cttcaagtcc agattgatgt
    11821 aacctgttta aaagttgatg aagatcagat gttaaatcca tatcaaatga ttgtaatgca
    11881 ttcatttctt ggaacgtttg cactggagca tcatcacgta aaaggaagtg aagacgctct
    11941 tcagcttctt tcaatccgta caacatacta tggtcttcca tttgcgaaac aagatatgga
    12001 tcttgtaaac agttttcata tttctctctt ttttgttcaa gctcttcatc tgttataagt
    12061 aacatgcccg ctatttcatg aattgcattt tttacagctc gaattggttc catatgtgcg
    12121 ccgccagcac agacgagatt cataccatct ttccttgtat ttttcgcaat gacccatatg
    12181 ctcggaatac catgttccat cgtcgcgttg aaaacgtata attcatatcc agtaattgtg
    12241 cgtaagcgtt ccaacattag ttgcaattca gtatcattgg ctgaactaag atcgagacgg
    12301 ggaagaggta attcggcata ccaagtgagc aaaaaggcgt cacgctctac aatttctaaa
    12361 atgccgtgaa aaattgcttc ttctaaacta ccaccaattg cacatccatt tgatgtttca
    12421 tacacgaaag catctctatg accaaggcta taataagcga ttgattctgg aactagaagg
    12481 ggcctgcttt gtaataaaga atatccccat acccagtttt gctcataatc aggatcaaac
    12541 ggcttaaatg gaaaactatc acgattgtaa tgttcatttg tatgcacacc aagtgtgagg
    12601 ggattcagtg caatatcttc tagctcacga aaactgccat gtacatttgt tttttttcca
    12661 cgaggcgaca taccgcaata gcgttctaaa ccttctaaaa tagcggttgc ttcactaagt
    12721 gaaaatgaat gagtccggcc cgcgacacct tcatttccaa acagtaacgg catgtttata
    12781 atgacatcag caaacggtaa tagagaatgt tgcattttac cgtttaaaat accagtccgg
    12841 taatctaaat agtctctcgt taaaaatgtg tttagctcat gaatggaacg acagcgatac
    12901 gtttcagtac tcgttttcaa acttggttgt aaagaaattt gcgctgcatc tgctgtatcg
    12961 tcaggcaaat tgctgcatac cggacagaga gggtctggaa gaaacgaatt ccgggtacat
    13021 tgtaacgttt gtaagtccag taaaatgagt tcgttttcta aagaagaata tccatgagct
    13081 aatattttct ctgtttcagc atgaatgagc tggcacattt gtaacattcc attttgggtg
    13141 gcgcgtacat cacgcctcgt cacgttctct gcttttaatg catattttcg ttgtagttcc
    13201 cacatttctt tttgatcaaa gccagctata aaccggcgtc catcagcgca gtgggaacat
    13261 ccagttgtaa gaggcttcac gtaaggaccg ataatacctt caccaaacga agtaaacgcg
    13321 cgaagccacg gaatattatt tgagcgaaag ataagctcag catcacgatg tacggaagaa
    13381 ggagacccgt catgtaaaac gagagcaaga tgaatgtttt cagggagagc ttctgtaatt
    13441 gtatgctggc ggatgagtga atattgcttg cacaattgct catgtacata gtctgtgagt
    13501 aggccatctc ctataagtag tatgttttga gtcattggtc atcctccttt gcaattaata
    13561 ccccatatac accgtctaag ttgtctctta aaaatgactc aatagctaaa tcaaaaacga
    13621 atggatacaa gttgttttcc gttaaatttt gcaaagcaac ttgtaaagac tgtacgcctg
    13681 gaatttcttc ctcttcttgt attgctactc taacaggatc cgtactatat aaaacaatgg
    13741 atgattccgg taacatatta gctttataag gaatctcttc attttgaata tgaaggagtg
    13801 cttgttgcag agcatttctt aatgcgagtg ttatattaat atttaccgca ccataccatc
    13861 tatcattaat accgatccaa acgacaggaa aaccaagtaa ctcctcactc attcctactt
    13921 taggtatttc atgaattgta gagagagcat cgtagtaaaa cctacaatgt ttatcatgaa
    13981 tttcggttaa ataaagctct gtaatctctt ctagcatatg tgattggcgt tcatataact
    14041 tattatttaa atgtttttgg agtgctcggt atacaccttc tgtcatcgtt tccccagcac
    14101 caataccgat atcagtatgt tcggggataa gacgatgaat catttcagct acatatgttt
    14161 caactcctgt taagccagct tcgcggcgtg cttcattatg agttaatcca ccgcaagtta
    14221 tagtaggaag gggagaggta ggtccgtctg ataatggatt tgcaacttga atattgcact
    14281 gtgataaagg caattgattt aaatcttgtt catcccacat gtggaatatg ccagcttctt
    14341 tagaagttaa cgtatcaaaa aaacgaaaaa gttcagttga agtatattgt ccggaacgtt
    14401 gggcaaggtt ttcttgaaga ttttgcaccg tatcaattgt aaagatttca tcggttgcga
    14461 gaagatgttt tatgaaaggg tgccactttc cttcaagtgt ttccaagttt aataaaaaga
    14521 attgaggatt atgctgccta tgtgaatctt cagcgacatg tttaaataac tcaaaaacga
    14581 taacatttgc taacattgca gatgcaattg gtgagaaagg ttcaggtgga ttttcacttt
    14641 gtaaagtagt ttcgtgtaga cgatgccaag ctgattccca gcattcttca cggtctacgg
    14701 ttacgacggg tccagctaaa ccaattcttg ataagcaaat agctggtatg aaatttttct
    14761 taaactctct acaaatagta tggattgctc ttaaactttc aatatctcca ttttgggaaa
    14821 cgtataaaat ccagtcgaaa ggctcgaata cttcatgtaa agggcgatca attgtaatat
    14881 ctatttcttg aataagtaca ttgtcatcat ttgcatatgc acgttcgctt aattcatgaa
    14941 ttcgatcgta gtttgtttca gcacgatctg taacaagata atgaaatgta ggtaaaccag
    15001 attctaataa agaagaaact agggaagtaa gcatatcgcc agaaccaatt ataagcacat
    15061 ttgctgcgcg gtacgtttcg aattttaaag cgcctgaatg ggaatcagct tctaaaaact
    15121 caatttgcga agcatatctg tcgagtaatg cactgtttaa ttcgtgggga gcatcttggc
    15181 ttacatcacg aacgaaacca ttttcatata aaatctctcc aatttcaaat acacgatttt
    15241 gataggggag agggagacca tcggttattt ctgtcaaaga atgattaccg ttaaacatag
    15301 gcattaattt ctcaatccag tcataaatcc catcaccatc catacggaat gaactggagt
    15361 tatttcgaaa gtaaacaccc ccgtttgaat cggggaggaa gaaagtatcc ttatttgctt
    15421 taagttttgc atgaactgga aggttattca tgtttatccc ccttacgttt taggcataca
    15481 ttattagtct atgtagtgtg atttgtccca tatgaacata atgaaaaaag gctgtagaat
    15541 gattcattct acagccttta atagattaat aatctatcaa ccttctaata ataatgattt
    15601 tggatcttca agcatatctt taacagcaac aaggaagcta actgcttctt taccatcaac
    15661 aatacggtga tcgtaagata gtgcaaggta catcattgga cggttttcca tacgctctgc
    15721 atcaattgca actggacgta cttggatttt atgcatccct agaataccta cttgtggact
    15781 atttaggatt ggtgtcgaca ttagagaacc gaacacacca ccatttgtaa ttgtaaatgt
    15841 accaccttgt agctctttta atgaaagttt attatcgcgt gctttcagac ctaaattacg
    15901 aatctcgctt tcaatttcag cgaagttcaa ttggttagca tcgcgtacaa ctggaacaac
    15961 taatccatct ggagctgcta ctgcaatacc gatatcatag aattttttaa tgataagctc
    16021 atcgccttga atttcagcat ttaataatgg gaactgtttt aatgctgcaa caactgcttt
    16081 tgtgaagaat gacataaagc caagacgtac atcatgtttt ttctcgaaag catctttgcg
    16141 ttctttacgt aattccatga ttgcactcat atcaacttcg ttaaatgtag ttaacattgc
    16201 agatgtttgt tgaacttcta caagacgttt tgcaattgtt tgacggcggc gggacatttt
    16261 cacacgctca actggttttt caaattcagt ttttgcaact ggagccggac tttgttttgg
    16321 agcagctggt gcttcttttg gcgctgcagc gtgagcttgt acatcatgtg gtctcacacg
    16381 tccaagtgga tctgtgctac gtacttcgtt taaatcgatt cctaattcac gagccatttt
    16441 gcgagcagct ggtgatgcga taggacgatt tgtatttggt aaaccttgca acgctttatt
    16501 ttgttcagca cttggagctg ctgctttcgg tgcttcagta gtttcttgtt ttggttgctc
    16561 agccaatgga gctggtgtac ttactgcaac tgctgcgccg tttgcatcta aaattgcgat
    16621 agtagcacca acttcaactg tatctccagg ttcgcctagt aacttcgata caatacctga
    16681 atcctctgca atgatttcta cattgacttt gtcagtctca agctcaacaa cgctgccacc
    16741 tttctcaact ttgtcgccta cgttgataag ccattgtgaa atagttcctt ctgaaataga
    16801 ttctgcaagc tcaggtactt taatttcgat cattttaaat gtcctcccct tatttgccta
    16861 acggtgtgtt ttatcttctt taatcttcgg taatctccat ttgttagcct gtctgtggca
    16921 gactatctgc cacagacaag cctgaaaaac tcattgttac tttcagttgc tgaaaacttc
    16981 aatttcttgt ttatcttgac ggaagttgta cttcacatct aaagcgtgtg caacgattaa
    17041 ttcttgctca gctttgtgag cgaatggatc gccaccagat gggctagaac gatccgggcg
    17101 tccaatgtaa cctgttttca ctttatcccc agctagttcg aacagaattg gagccatgta
    17161 atgccatgcg cccatattac gaggttcttc ttgaacccaa atgatttctt ctaagttttt
    17221 aaagcgttta ataatagatt gaactttttc agcagggaat ggatacaact gctcgatacg
    17281 aaccatatga acttcatcta ggctgtactc atgcttacca ctttcgattt ctgctgctaa
    17341 gtcaattgcc attttacctg tacttaaaac aagacgtttt actttatttg gtttcgcacc
    17401 aaggttttct tgttctaaag caggttggaa acgtccttcg cttaactgac tagcagttga
    17461 aagcgtaagt gggtgacgta ataaactctt tggcgtcata agcactaacg gtcgaacggc
    17521 ttctgttcct aagatagatg cttgacgacg taaaatatgg aagtattgtg ccgcgctcgt
    17581 taagtttgca actgtccagt tgttctcagc agctaattgt aagaaacgct ctggacgtgc
    17641 actagagtgt tctggccctt gaccttcata accgtgtggt aatagaagaa ctaaaccaga
    17701 tttttgaccc cattttgctc ttcctgctga aacatattga tcaaataatg cttgcgcagt
    17761 atttgagaag tcaccgtatt gagcttccca catcacaaga gtttctggag caaatacgtt
    17821 gtaaccatat tcgtaaccaa caacagcagc ttctgataac ggactgttat gaacagagaa
    17881 tgatgcgtta atgttcggta aacggtgtaa tggtgaatac gtttcgtttg tatcagtatc
    17941 gtgtaatacg atatgacggt gcgcgaatgt accacgctgt gaatcttgac cagttaaacg
    18001 aattggcgta ccttcttgta aaattgaagc gaatgctaac gattcagcaa gtgcccattc
    18061 aattttaccg ttctcttcaa gagcatcttt acggcgctca agaattttct tcacttttgg
    18121 atatacgtta aagccttcag gccaagataa tagtccttca ttaattgcac gaagtgattc
    18181 aattgaaaca ccagtgtcaa tcggttgaat tccttttgca acaacctctg gaactttaac
    18241 gtgaattgtt gcagcactcg tatcagctgg tggcacttgt gcgtattcag cctttaattc
    18301 ctcttgtata aactgagtaa ttgtttcaac ctcatctgca ttcagaacgc cagcagattg
    18361 taattgatct gcataaattg ctcttacagt tgggtgattt ttaatttttt tgtacacttg
    18421 tggttgcgta actgctggat catccatttc gttatgacca tatcggcggt aaccgattaa
    18481 atcgattaag aagtcctttt tgaacagcgt acgatattgg atcgcaaggt ttgcagcagc
    18541 aagacaagct tccggatcat cagcattcac gtgaacaatc ggaatatcga aaccttttgc
    18601 aaggtcgctt gaatatttag tagaacgaga atcatagcta tcagtcgtaa agccgactgc
    18661 attatttgcg ataacatgaa tagttccgcc agtttggtat gcattcaatc tacttaagtt
    18721 gagtgtctca gacacaacac cttgaccagg gaatgcagca tcaccatgaa ctaaaattac
    18781 gaatgatttt gtagtatctt gttctggaag accagatttt ttacgattct cttgagctgc
    18841 acgtgcgaaa ccttcaacaa cagggttaac gaactcaaga tgactcgggt tatttgctaa
    18901 tgtaacacga gtgctaactt cttcattacc aacgacttgt tctctaccta aatggtattt
    18961 cacgtcgcca gtccagccag catttgccac tgcaccttct atttttgcat gtttgaattc
    19021 tgcaaacatg tgattatatg gcttttctaa tacgtgagcg agtacgctta gacgaccgcg
    19081 gtgagccata ccaatcatga catcttctac gccgccttta gcaccttcag aaacaatttc
    19141 atctagtaca ggtacaagca tatcaacgcc ctctattgag aaacgttttt gaccaacgaa
    19201 tgttttatgc aagaattgct cgaaaccttc aacagcagct aaacgtttta aaagagcagt
    19261 tcgtttttta tttgataatg gttgacgcaa tgaatttgat tccaccattt gatgcaacca
    19321 cgcgcgttct tcactatctt gtatatgtga gaattcataa gctaaagatt ttgtataaac
    19381 gtcttttaat ctatgaatta catcaagtgc agtgtgaata ccctctggtg catcttgcca
    19441 tactgttttt gctggaatcg ctttcaagtc agcatcgctc agttcgttca ttgttttctc
    19501 gataagagat tgtccgtttg cagcatcttc catcggatta atgtgagcca atgtatgccc
    19561 gaaagaacgg atctgttcaa caagttgaac gactttaaga atcttttcaa tgttccctgt
    19621 gttttgagga gaaaaatgtg ttgctgtgtt gtcccctgtt acgacatcat cttgaaacga
    19681 aggagctcca aaaatttcaa aaagctcttg taattccgga tcaacagaac ctgctccagt
    19741 tacgtaaaga tcatactgtt caataacata accaaggttc ggaccatgga acttggccca
    19801 agggtttgtc gttgtattct tcctcgtcat ttgtttaaac ctcccaatgc atataatcct
    19861 ttttccatac aaaaaggtgc attttgctct tttcaataat tgatgaacca ataatcaatg
    19921 taaatgtttt tctttactct tatgttatta caataattta cataatacca aacactatta
    19981 cttatctgtt ttgtaaaaaa acattcacaa taacttatca cccaagttaa tctttcatgt
    20041 tataaagtaa tttcacggga aaacggggtg gatatatttg gtatacctac attgatacct
    20101 ataattgttg catttaaata taagtataac tatcagaatg tttcgataaa gtttagttcg
    20161 aattatgtat attggaataa taagcgcttt cattgatatt atacaacaat ataacggaat
    20221 atagtataaa aaataaaaaa ttatgaattt accataaact ttatctcaat agtgttaaat
    20281 atcgaaagga aaatgaagga tttctacaaa aaaagtggct atacataaaa aatgcttcat
    20341 aaaccgttag tttctataaa tatggcgaaa aacaacgtaa aaacaatagc gcatttcacc
    20401 cgataaagag cagaatgaaa cattttaaaa ggataaaaca aatatggaga tattaaattt
    20461 tcataaaaac ggagaggaga tatagtaacg gctatataca ttgttccatg tttcatttca
    20521 aaatagacgt gctgaatttg aaaaagtttc ttctatataa atagaatgaa aaatagacga
    20581 aatgaatgta aaggaaactt gacgtaaagt ttactttaca tatatactcg gtataaggaa
    20641 ggagggagaa atttccttgg aaaataaaat ggttgaatac cgaaaaaaat ttggactatc
    20701 tcaagaaaaa ttggctgaga aacttggagt ttccagacaa accatcattt caattgaaaa
    20761 gggaaaatat gatccatcac ttccgttagc atttgaaata gcaaaaacat ttcagacaac
    20821 gatagaacat gtatttattt atgaaggaaa agaagagggg gagaaaggat gaattattca
    20881 caaaagtact ttgtaattat ggggattatt tttctattta tgagtggatt tatgatatta
    20941 acaggtataa tgacgcattc tgcaccaccg gctccaacgt atacattgct tgcaatgatg
    21001 atcatgtgtt tttgcctaag ctacttgcac ccgcaattta aagaaaaaga tgagcgaatg
    21061 aaactcattc gttataaagg aatgttcttc agtttttttg cactaacggc atactatctt
    21121 cttttctcta ttggcttaaa cttaaaagta attacgctat ctgcggttga actattgaat
    21181 atattaatgg cacttacgat gagtacagtt tttatatcgt ttgttgtttt atcgaaaaga
    21241 tattaagatg taaaagagaa aggaagatta acatatgcaa atgatgtatg cttttggcat
    21301 ggggcttgta ttatttttag cggtattctt atttattcgt aaagacattc aaggcggaac
    21361 gttaacgaag cgaggatttt ataaaatgat cggctgttta gttgttatgt ttatagcgat
    21421 tatcgtaatg attgttttaa ttaataaaac attatagaat ttaaagacgg aaccttactt
    21481 tatagtaagg tttttctttt tgaaaataaa actaaaaatt accattaaat ccattttcta
    21541 tctatacctt acattatata atccaatgaa atgatagata aggagaatag taaatgaata
    21601 aaaaggctat cttctttata gcgatatgtc tattacttat ataatatgta acaaatgaga
    21661 acaagttcca cctatattag tataggaggg gcatgaatac tacgttacga atgaacctgc
    21721 caaggcagaa gaagccgggc aaaaacttgg agaagtgacg aagaaaattg aaacaagcaa
    21781 acagcctact aaagatagtg aatccaacgt attagaagaa aaaacagaag tatttgaaat
    21841 gattttagaa gaagaggatg aaaggccgcc tttagttgta aaagaaccta atagtgaagg
    21901 atatagagta gcaaggcaga tgttaaagca agtactataa taatgaagaa acaaattttt
    21961 aatagagagt agtgacgtta tgagatggaa agcaggaacg tttgaaaaaa tagaaacgaa
    22021 tgactcatct attgagcaac ttataaatac atttaagaaa caaaacttaa atggtggagc
    22081 agtaataagc tgttttaaag tacataacga aaattttttc aaagaaatac cttatgaaat
    22141 agatagatac gagcactttt tcaaaaaagt cttcaactct ttagatataa ttaataactt
    22201 agaggaatta aaaatacata catcagaaaa atataagttt caatttaaat ataatagtgc
    22261 ggtaatactt gatgggagta ttgcatttca aattataaga ggcggagcat ataaatattt
    22321 tccagagaga atggtagttg cgaagcaatt agcgagcgat gtatgccaat acatgttcca
    22381 agatcgttat gaggatatta tagtgttcga aagtcaaagc ccttggacgg actggtttta
    22441 cgatgttgca tgggataata cttggatggt gttagatagt aaggagcata aaatgtggtt
    22501 agtttgtgct acggatacgg attgatagaa gagggggcct tgtaggaatg ctgcaaggcc
    22561 ctttatcttt tgggaatgaa tagaaaacga atcatataaa tgctatacta aaaaacgttt
    22621 gtaatgtcag tttcatacta ttgtataatg ctgacttact agaaaagata tgaggagaat
    22681 gaacgtgaaa aagatacaga aattattgct gttaatgatg gtagtaggat taacagtagg
    22741 tgttttagca gggtgtgcaa atccgaaaga tactacagaa gaatttttaa cagcgataca
    22801 aaaaggtgat gtagaaaagg ctcgtacatt tgttgagagt gacaaggaat ttaataaact
    22861 aaatgaaaaa acagatgatg ctgaggcaaa agcaatgctg agtgcaatta cgaaaaactt
    22921 taaatttgaa aagccagaag aagtatcgaa aaaggatgac aaagcagaag tgaaagtgaa
    22981 aattacatct gctgatctat ccgttgctgt aacaaaagca gtgggagaag ttatgccaat
    23041 ggccttcgct agtgctttta gcgaagacaa agaacaatct gaaaaagcaa tcgaaaaaac
    23101 aatgacatca actatcgtca aaaacttagc ggataaagat gcagcaatgg caactcgcga
    23161 agttacattg aacttaaaga aaaacaaaga tggcgactat aaaatcgttg ctgatgataa
    23221 cttgaaagaa gtattatttg ccaatgcgaa gtctttggag aagatgtttg gtgggaagtg
    23281 attgactggc aagattttta gtttttataa gaagtaactt ggataaaaag agacaccata
    23341 tcacctaata ggttgatatg gtgttttttt atgaccccgg agaggctcga actcacgacc
    23401 tccaccctgt caaggtggcg ctctccctgc tgagctacgg gatcttaaaa aatgcttatg
    23461 taatagcatc tttaataatt atgctaaagc aattatatat aattaactga aattttacaa
    23521 tatttttata gtaag
//
