LOCUS       NZ_CP093291            23915 bp    DNA     circular CON 24-MAR-2024
DEFINITION  Bacillus mycoides strain DSM 2048 chromosome, complete genome.
ACCESSION   NZ_CP093291
VERSION     NZ_CP093291.1
KEYWORDS    RefSeq.
SOURCE      Bacillus mycoides (Bacillus weihenstephanensis)
  ORGANISM  Bacillus mycoides
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus cereus group.
REFERENCE   1  (bases 1 to 5285600)
  AUTHORS   Chiba,A., Peine,M., Kublik,S., Baum,C., Schloter,M. and Schulz,S.
  TITLE     Complete genome sequence of Bacillus mycoides, isolated from an
            agricultural field in Rostock, Germany
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5285600)
  AUTHORS   Chiba,A., Peine,M., Kublik,S., Baum,C., Schloter,M. and Schulz,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2022) Research Unit Comparative Microbiome
            Analysis, Helmholtz Zentrum Muenchen, Ingolstaedter Landstr.1,
            Neuherberg 85764, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-MAR-2021
            Assembly Method                   :: HGAP v. 4
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 1166.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022630575.1-RS_2024_03_24
            Annotation Date                   :: 03/24/2024 09:23:57
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,704
            CDSs (total)                      :: 5,549
            Genes (coding)                    :: 5,305
            CDSs (with protein)               :: 5,305
            Genes (RNA)                       :: 155
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 108
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 244
            CDSs (without protein)            :: 244
            Pseudo Genes (ambiguous residues) :: 0 of 244
            Pseudo Genes (frameshifted)       :: 93 of 244
            Pseudo Genes (incomplete)         :: 175 of 244
            Pseudo Genes (internal stop)      :: 63 of 244
            Pseudo Genes (multiple problems)  :: 79 of 244
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:31:00
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 71333
            Orig. end                         :: 95248
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP093291.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Research Unit Comparative
            Microbiome Analysis, German Research Center for Environmental
            Health, Ingolstaedter Landstr. 1 85764 Neuherberg.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23915
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..23915
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23915
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13915](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13915)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(536..1474)
                     /locus_tag="MN093_RS00375"
                     /old_locus_tag="MN093_00375"
     CDS             complement(536..1474)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913375.1"
                     /locus_tag="MN093_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00375"
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_241875704.1"
                     /transl_table=11
                     /translation="MLKKVFAMSTTVVLAAGLLSGCGTKESSASKNEDTKKGYVPKTLN
                     VQFVPSQNADTLEAKAKPLEKLLSDKLNIPVKVSISTNYNTIVEAMASKQVDVGFLPPT
                     AYVLAHEKKAANVILQAQRFGVDDETGAPTKDLVDVYKSEFVVKKDSNINSVKDLKGKK
                     IGYQDVTSSAGYVWPAAVLLKEGIDPLKDVKPVTLKGHDQLLIALLNGDVDAAVVFQDA
                     RNIVKKDYPNIFDQTKIVKFTEKIPNDTISVRSDLDAEWSKKLQDAFIEIGKNEEGHKI
                     IKEVYSHEGYVKSDDSKFDIVREYGKKVKTQ"
     misc_feature    1495..1511
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 28.44"
                     /tool="antismash"
     gene            1660..3243
                     /locus_tag="MN093_RS00380"
                     /old_locus_tag="MN093_00380"
     CDS             1660..3243
                     /EC_number="3.1.-.-"
                     /EC_number="3.1.3.5"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0008253 - 5'-nucleotidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0009166 - nucleotide catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002199635.1"
                     /locus_tag="MN093_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00380"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_131245292.1"
                     /transl_table=11
                     /translation="MNPNQIVTLNILLTSDVHGTVYPIHYQDNSKAEIGLAKISTLIKK
                     ERSQNANVLLIDNGDFIQGTPFTYHYATYEKDMENPMSLLANYLEYDIAIIGNHEFNYG
                     MDILNNAVATANSPYLSANILDKNRKEPYFGKPYIIKHIESNIKIAILGVTTHYIPHWE
                     QAHHIKDLQFEDAFETTKKWVSYIRKHEKPDLLVVAYHGGFERDLQTGVPTEVLTGENQ
                     GYAMCHEIEGIDILLTGHQHREIAHTVINGVTILQTGCNGHSVGKVTVTFEKAEQKWVK
                     KESYSELLPVQGISADQDVLSLVANYEEKTQNWLDKPIGIIYGDMQISDAMQTRLQDHP
                     FIEFINKIQMDIANVSISCTSLFHNTSPGFPKHVTMRDIVSNYIYPNTLKVIRITGADI
                     KDALELSASYFTLKADGTIIVNPTYIEPKPQHYNYDMWEGISYVLNISKPIGERVESLQ
                     YKGAPLNMNEEYDVVMNNYRASGGGNFFMFQNKPVVKDIPTDMSELIANYILKHKKIEA
                     TKNENWKVIK"
     gene            complement(3284..3523)
                     /locus_tag="MN093_RS00385"
                     /old_locus_tag="MN093_00385"
     CDS             complement(3284..3523)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002172959.1"
                     /locus_tag="MN093_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00385"
                     /product="DUF896 domain-containing protein"
                     /protein_id="WP_002014431.1"
                     /transl_table=11
                     /translation="MPSQELIERINFLAKKAKAEGLTEEEQRERQSLREQYLKGFRQNM
                     LNELKGIKVVNEEGTDVTPAKLKALKKQDNAKLN"
     gene            complement(3569..4225)
                     /locus_tag="MN093_RS00390"
                     /old_locus_tag="MN093_00390"
     CDS             complement(3569..4225)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016111193.1"
                     /locus_tag="MN093_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00390"
                     /product="recombinase family protein"
                     /protein_id="WP_002014433.1"
                     /transl_table=11
                     /translation="MNAIIYARVSTTKEEQETSLLRQKDELLHLAERYQMDVTKVIEEQ
                     ASGYTIERDGILEVLDTIRDEQVDVLLIQDETRLGRGNAKIALMHCLHKEGIKVYTHTH
                     SGELQLSDSDSMVLNIIGIVEEYQRKIHNLKIKRGMQRAVEKGFRPENNLKNRHLSVGR
                     EKKEVPIEEIVRLRRNELTFEEIAATLRGFGHDVSKATVHRRYVEYTKQLLDKEE"
     misc_feature    complement(4286..4299)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 22.42"
                     /tool="antismash"
     gene            4367..4981
                     /gene="lexA"
                     /locus_tag="MN093_RS00395"
                     /old_locus_tag="MN093_00395"
     CDS             4367..4981
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413738.1"
                     /locus_tag="MN093_RS00395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00395"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_002087894.1"
                     /transl_table=11
                     /translation="MEKLTKRQQDILDFIKLKVQEKGYPPSVREIGQAVGLASSSTVHG
                     HLSRLEEKGYIRRDPTKPRAIEILGDNRTETQSVIQVPIIGKVTAGLPITAVESVEDHF
                     PLPASIVAGADQVFMLRISGDSMIEAGIFDGDLVVVRQQQSAYNGEIVVALTEDNEATV
                     KRFYKEKDHFRLQPENSSLEPIILKQVSVIGKVIGVYRDLH"
     gene            complement(5085..5888)
                     /locus_tag="MN093_RS00400"
                     /old_locus_tag="MN093_00400"
     CDS             complement(5085..5888)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016512438.1"
                     /locus_tag="MN093_RS00400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00400"
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_207391870.1"
                     /transl_table=11
                     /translation="MMKKILLVAIACIIIGVIGISQTYEKAVQTAEKGDKEDVIKNETL
                     KNVEVKLDAGDIVVQKSPDSSFYVKQKGDVSKQEIRIAEDGDTLKIIGEIEKGVSFDFS
                     FYNFGFQTPTLPILVPERSYQEIKVNSSAGQIEISNVKSDRVSVETLAGEVDLKHVTAK
                     SVEGSTKAGEVNFKKVIGKVTAKTASGDIDIIDHDSKYDLEVSSTAGDVDITLLEKPQD
                     AVITGQTAAGDVTIFNEDNKNITIGNGSKKISGKTAAGDVTIETR"
     gene            complement(5889..6431)
                     /locus_tag="MN093_RS00405"
                     /old_locus_tag="MN093_00405"
     CDS             complement(5889..6431)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031379.1"
                     /locus_tag="MN093_RS00405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00405"
                     /product="DUF1700 domain-containing protein"
                     /protein_id="WP_002128581.1"
                     /transl_table=11
                     /translation="MSKEQFLKELSSHLRKLPEEERQDILFDYEEHFQFGMEEGKTESE
                     IIKGLGSPKVIAKDLLAMYRFDEMKKDPSTSNVTRAVMAAVGLSLFNFIIVLGPLVAII
                     AFIFSFWVGGIASVVTPFFVIVKVFMGTFIWLDLFVSITFVGVGLLLCIVAYYSTKWFK
                     RLCVRYVVWNFKMIKGE"
     gene            complement(6424..6747)
                     /locus_tag="MN093_RS00410"
                     /old_locus_tag="MN093_00410"
     CDS             complement(6424..6747)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016105867.1"
                     /locus_tag="MN093_RS00410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00410"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_002066545.1"
                     /transl_table=11
                     /translation="MNVQFKKGVLELCVLALVKRKDCYGYELVQQISNKFLISEGSVYP
                     LLRRLTKEGYFQTYLKESTEGPPRKYYQLTEQGEMQLTLLVTEWRDFAKGVQEIIEGVE
                     WDE"
     gene            complement(6976..8778)
                     /locus_tag="MN093_RS00415"
                     /old_locus_tag="MN093_00415"
     CDS             complement(6976..8778)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016096316.1"
                     /locus_tag="MN093_RS00415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00415"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_131245290.1"
                     /transl_table=11
                     /translation="MENLLYFAKKLHSFSGKTLYLNLLGMSLVSLLEGIGILLLIPMIS
                     VSGVVKVNSGSTPGSEVFEFLHNIPETLSLLIILSVYIFLVVAQSLLQQNLTLRNMKIL
                     INFTNHIRLEIYRTLLQANWAFFVKKRKSDLINALTEELGRVVNGTNLFFQMLTALIFT
                     LIQVGIALWLSATITLFVLFAGLVLAFFSRHFIKKSKALGNQKSEVARSYLGGITDHFN
                     GIKDIKSNTLEESRYTWLHTWCQRIEQEQLAFMKLKNSSQLFYKIASSILIAFLIFTSI
                     KLFQAQPGQLLLIILIFSRLWPRFTSIQSNLEQLAASIPAFKSLIELQEECKKAEELQD
                     IEQCYKYVKPMSIKKGIECRNVYFRYNQKEPVYALRNINLQIPTNCMTAIVGRSGAGKS
                     TLIDILMGLVHPEKGKVLLDDSTITSDNLLALRKSISYVQQDPFLFNASIRENLLMIEP
                     NASEDQIWAALDFAAAAEFVRTLPNGLDTFIGDRGVRLSGGERQRLVLARAILRKPSIL
                     VLDEATSSLDTENEALIQSALEKLKGQMTIIVIAHRLSTIRNADQVIVLDKGEVVQQGA
                     FNQLARERKGVFRNLLGKQVEVSS"
     gene            complement(8792..9979)
                     /locus_tag="MN093_RS00420"
                     /old_locus_tag="MN093_00420"
     CDS             complement(8792..9979)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002014444.1"
                     /locus_tag="MN093_RS00420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00420"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_131245289.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 3.1e-64, bitscore:
                     215.2, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNSYGLDLNGVAKELKLQLEILKSGNATELQEINKEWFENIDWD
                     RFLELTIHHRVYSFIYPKMKEMDKKLVPVRVIQVLHQYFKMNTFQMLHLSAEMELVSKL
                     FTENEIRTLFLKGPLLAHDLYGDISLRTSSDLDVLIPIQQLKKAEKLLLEQGYVKDGDI
                     QTILNDWKWRHHHMEFFHPQKQIKIEIHWRLHPGPGKEPSFEELWERKRTSTLTSYPIY
                     LLGSEDLFLFLISHGARHGWSRLRWLLDINQMVKQGLDWKEVYKLFTTYQCGHVGGQAL
                     ILATELLNATIPEEMKVLAGQRRSRKLAQDAIFYIRKMINLHTDPVPDEVAAYHSRHLF
                     SLMSNQQKILFIISYFYPYPIDAKTLPLPKYLHFLYFPLRPILCTWRKARKHVLS"
     misc_feature    9990..10005
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.51"
                     /tool="antismash"
     gene            complement(10001..10453)
                     /locus_tag="MN093_RS00425"
                     /old_locus_tag="MN093_00425"
     CDS             complement(10001..10453)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016130929.1"
                     /locus_tag="MN093_RS00425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00425"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_131245288.1"
                     /sec_met_domain="PF13471 (E-value: 3.1e-23, bitscore: 80.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIVQKIRKFFSLDMKTMFLFIEAYMYLGWARFLKFMPFSKIAPT
                     LGTHMDETSLSCNESNKLILRSISEAIHIMSQHTFWESKCLVSAIAGMEMLKRRQIEST
                     LYLGTAKDKNGKMVAHAWLRSGPFYITGAEEMERFTVVSKFARIIG"
     gene            complement(10491..10796)
                     /locus_tag="MN093_RS00430"
                     /old_locus_tag="MN093_00430"
     CDS             complement(10491..10796)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160860.1"
                     /locus_tag="MN093_RS00430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00430"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_113769561.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3e-26,
                     bitscore: 89.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.2e-16, bitscore: 57.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRKQNILLYHTIVQGKGNIVSNMDGEKVMLSIQNGKYYNLGEMG
                     GTIWDFIETPTSVTQLVASLIAEYEVEQSTCEEQVISFLELLLEENLVEIVEGRNK"
     aSDomain        complement(10512..10754)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MN093_RS00430_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.50E-28"
                     /identifier="RREFam002.1"
                     /label="MN093_RS00430"
                     /locus_tag="MN093_RS00430"
                     /protein_end="95"
                     /protein_start="14"
                     /score="89.6"
                     /tool="antismash"
                     /translation="QGKGNIVSNMDGEKVMLSIQNGKYYNLGEMGGTIWDFIETPTSVT
                     QLVASLIAEYEVEQSTCEEQVISFLELLLEENLVEI"
     gene            complement(10800..11735)
                     /locus_tag="MN093_RS00435"
                     /old_locus_tag="MN093_00435"
     CDS             complement(10800..11735)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160859.1"
                     /locus_tag="MN093_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00435"
                     /product="aldolase"
                     /protein_id="WP_113769560.1"
                     /transl_table=11
                     /translation="MINTHTVKKNIYKAFGLNLLSEIILPELPQINKQSDKPDVLITID
                     DLSELWLEIAGQPNQFLVRDNLVMFQLPNLATFAIRDGNRISVSPVNEADENEIRIYIL
                     GTCMGTILMQRRILPLHGSAIAINGKAYAFIGDSGAGKSTLATAFLSKGYQLLSDDVIA
                     VSFSNDGHVPLVFSAYPQQKLWQETLTAFGMKSSQYCSLFERETKYAVPVNSQFSTETL
                     PLAGVFELVKTEREGIDIYPIQRLERLHTLFRHSYRNFLIPRLGLMDWHFSTSTRIIEQ
                     IDIFRLRRPTCEFTAHQLVSLVLATLNKEE"
     gene            complement(11835..11966)
                     /locus_tag="MN093_RS00440"
                     /old_locus_tag="MN093_00440"
     CDS             complement(11835..11966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160858.1"
                     /locus_tag="MN093_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00440"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_113769559.1"
                     /transl_table=11
                     /translation="MKKEWKTPVLETLDIKMTMASGYEGYHDEAYNGEPATGPHHQS"
     gene            complement(11981..13915)
                     /locus_tag="MN093_RS00445"
                     /old_locus_tag="MN093_00445"
     CDS             complement(11981..13915)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160857.1"
                     /locus_tag="MN093_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00445"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_131245287.1"
                     /sec_met_domain="GATase_7 (E-value: 6.1e-22, bitscore:
                     76.1, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 5.6e-21, bitscore:
                     73.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAITGILHFDDEPISIEHGARLMNDLQKYPADDVQIWHTNNVFL
                     GCHAQWITPESIGEQLPFYDYERQLAITADAIIDNRDELFGRLQVDYADRKKMTDSELI
                     LLSYERWGEEVPKYLVGDFAFMIWDERQQKLFGARDFSGSRTLYYYKDQQRFAFCTTIQ
                     PLLTLPYVQKQLNEQWLAEYLAICGMVDVVDVTMTPYKNIEQVPPSHSISIVGDKIMLM
                     RYCTLTSREKLKLKSNEEYVEAFQDVFQDAVTARLRTYRHVGAQLSGGLDSGSVVSFAA
                     KVLRTKNKRLHTYSYVPPSDFIDFTPKYRMANERPFIRSTVEHIEGIIDHFVDFQEGNP
                     LLEINDFLEMMEMPYKFFENSIWIKGIFEKAHEEGIGILLTGGRGNLSVSWGPAIEYYA
                     ILLKKLRWIRLYKEIDLYSKNIGVKKTKSLSYIWKFAFPFINKITPGIEIYRSPRLISS
                     ELSKRTDVFAKLKEHGIDEGGTLPNIYEERRRHFEELFHWNATNTLGTKQSLRYSLWKR
                     DPTNDIRVIRFCLSVPEEQYVQDGFDRALIRRATESFLPDKVRLNQHYRGVQGVDWVHR
                     MTPSWHIFVEELQCLSSERWIWEFLNEQVVKSAISKVREGPRPEYATNPEYRIAIRSLV
                     VSRFIKNFS"
     misc_feature    14465..14481
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 20.85"
                     /tool="antismash"
     misc_feature    14601..14614
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.36"
                     /tool="antismash"
     gene            complement(14721..15869)
                     /locus_tag="MN093_RS00450"
                     /old_locus_tag="MN093_00450"
     CDS             complement(14721..15869)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (40-167). E-value:
                     9.1e-13. Score: 40.0. Matches aSDomain:
                     nrpspksdomains_MN093_RS00450_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160856.1"
                     /locus_tag="MN093_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00450"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_113769557.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.2e-99,
                     bitscore: 332.3, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.2e-11, bitscore:
                     40.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVMIQQKRIYLSSPHMSGNEQTYIQDAFDTNWIAPLGPNVDAFEK
                     ELATFVGVKDAAAVSSGTAAIHLALRLLGVQKGDKVFCSSLTFVASANPIVYVGAEPIF
                     IDSEPETWNMSPQALECALCDADKEGKLPKAIIVVNLYGQSAKMDEILSLCNEYDVPVI
                     EDAAESLGSTYKGKASGTFGKFGVYSFNGNKIITTSGGGMLVSDDVEALQKARFLATQA
                     RDLASHYEHSVMGYNYRMSNILAGVGRAQLEVLEERVRARRFIFEQYYRELSNISGFQF
                     MPELENTCSNRWLTTLTIDEKEAGISIESLLGVLAKENIEARSVWKPLHMQPLFETMKY
                     YPHSGNTHVGEQLFKKGICLPSSSNMEDRELQRVIQCIKNAL"
     aSDomain        complement(15369..15749)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MN093_RS00450_Aminotran_1_2.1"
                     /evalue="9.10E-13"
                     /label="MN093_RS00450_Aminotran_1_2.1"
                     /locus_tag="MN093_RS00450"
                     /protein_end="167"
                     /protein_start="40"
                     /score="40.0"
                     /tool="antismash"
                     /translation="DAFEKELATFVGVKDAAAVSSGTAAIHLALRLLGVQKGDKVFCSS
                     LTFVASANPIVYVGAEPIFIDSEPETWNMSPQALECALCDADKEGKLPKAIIVVNLYGQ
                     SAKMDEILSLCNEYDVPVIEDAA"
     gene            complement(15881..16516)
                     /locus_tag="MN093_RS00455"
                     /old_locus_tag="MN093_00455"
     CDS             complement(15881..16516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002146232.1"
                     /locus_tag="MN093_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00455"
                     /product="acetyltransferase"
                     /protein_id="WP_131245286.1"
                     /transl_table=11
                     /translation="MKIAIIGHGGHSKVIQDSILSNNEYEIVGYLDDRYENIVTVDNLY
                     FGPISTAYDMINYFHQINFVIAIGNNKVRKAIVKKLCLSDEFYITLIHKTAVVSPSAKV
                     GNGTVVMPNVVINADTQIGNHAIINTGSVVEHDNIIGDFVHISPRATLTGSVLIEEGAH
                     IGAAATIIPSVKVREWSIIGAGAVVINDMPPKCIAVGIPAKVINEVSY"
     gene            complement(16513..17127)
                     /locus_tag="MN093_RS00460"
                     /old_locus_tag="MN093_00460"
     CDS             complement(16513..17127)
                     /EC_number="2.7.8.-"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006486 - protein glycosylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146: sugar transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002199623.1"
                     /locus_tag="MN093_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00460"
                     /product="sugar transferase"
                     /protein_id="WP_241875705.1"
                     /sec_met_domain="Bac_transf (E-value: 1.6e-64, bitscore:
                     215.0, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRFFDLLVSLSFLLVLSLPIIIVVILVRIKLGSPIIFKQQRPGL
                     YGKAFYLYKFRTMTDARDSKGELLADQVRLTSFGKFLRKYSLDEMPQLINVVKGNLSLV
                     GPRPLLIEYLPLYSNEQVKRHHVKPGITGWAQVNGRNAITWEKKFALDVWYVNNQSFSL
                     DMKILFLTVIKVLKSEGINQVGHVTMEPFTGAKSTVSGERK"
     gene            complement(17258..18892)
                     /locus_tag="MN093_RS00465"
                     /old_locus_tag="MN093_00465"
     CDS             complement(17258..18892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002160853.1"
                     /locus_tag="MN093_RS00465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00465"
                     /product="hypothetical protein"
                     /protein_id="WP_113769554.1"
                     /transl_table=11
                     /translation="MLNANRQHRLKIGIMLDSLVVSSWIEKMIYDIVHTEFLELSIVLI
                     NGNERVEKQNVFQQSVKKTSLYSKYLKWDYNYYSKYVRHNALKPVHMESLLSEYGCRIL
                     TIYPNKQGLQNEFSDSDLDVIRGGQLDVIIKLGFGTLHGEIINIARYGIWSYCFSGQGV
                     EAFWEMASRKIPLETRLQILASKPENHKVIYRTISPLNVESLFFNRNLLYWKVKDIVLR
                     RLFDLYKKGWSYITNLDTYNQPSLVNERPDKYPTNFQMIPFISRLAMHKLKSRLFMEHW
                     FIAFKNRKEERSRFHIIKAPLSRFYADPFVIERNERNFIFFEDYIYSEGKGNIAFVEVD
                     IESNSVSQPTTVLEKPYHLSYPFLIKDGGEIYMIPETSSNQTIELYKATNFPYEWEIEK
                     VLMENVNAVDTTIIQHEGKYWLFTNVFTDGSSLDELYLFHSDSLFGQWVSHPMNPIVSD
                     AKSARPAGNIFVHDGKLIRPSQNCLFSYGYSVNLNEIEILNEDSYREKKIKEITPSIFK
                     RNKGTHTYVFNEDLEVLDGRKQVLKFK"
     gene            complement(19173..21575)
                     /locus_tag="MN093_RS00470"
                     /old_locus_tag="MN093_00470"
     CDS             complement(19173..21575)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016100235.1"
                     /locus_tag="MN093_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00470"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_131245285.1"
                     /transl_table=11
                     /translation="MSIRVNLDDVDLTTKFPTHNDVLVYDSAKSKWIPKVLSFPLTGSV
                     SSSYVLELDRWNIKSDGTDSYETTKGINDALVWAKSQGYNHVVLSSGTYKLKIDPITFT
                     CIVLQSDMYFEMMDGCILELEANSSPWYSIFGVKGVKNVKISGGKIVGDKKTHKYELGV
                     KFVRGGINADGSLNSNPNFIRSEIVDRYENPGLLQNFRLWSIPGVVATGYSFYQYKDII
                     SNSTLVGVRNNGGFAPTSPTGRGWFAPIKDANKMIFVIDITSSPLSDTQIAQINAKVDN
                     QNWTHEWGQGIQINGSHNIVINNVEISDCTGDAIATAWLEYKLNSSDYIQEDMGSYIYI
                     HSCNLHHCRRQGISLTGSNDIYISNNKIHHIGKADDDVTVDGTAPMFGIDIESMWSETN
                     IPTWRPELNKSGLELNTRIYIFNNYIYDNARGHFVNVDGINVIVENNTFEGPNVGGVSS
                     YQNNWYVKYLNNTFIGCEFVVKGDNFVNGVVCNNGNIKLMDVQGAVVQNCQIKNGLFYG
                     YSSLGYFGTPVIDVTTSTFTFSKPHGMGNGAKVCFEQWVGKVPTGISVDKLYYTINVTA
                     TSFQVSEVLNGTPVTITDGGTPGFNISRYDYGRCYISDIMLEKEWSDSTADGGVDITLT
                     GGVIKNFTVKNYGLAIRVPENYVGRPNVVEGITVIEGPAQLECCNISGGKFMKIKTSRI
                     GGDIVLGSNDVNYNRKVNIDNCTFQNVALNFDGNVLNTRSTFLNSIIRKVDNENISVIT
                     LSYLENTSIALHWLTKEKTMVIARCIFNNVSTDITKSTLLIDNVVLT"
     gene            complement(21701..22762)
                     /locus_tag="MN093_RS00475"
                     /old_locus_tag="MN093_00475"
     CDS             complement(21701..22762)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084646.1"
                     /locus_tag="MN093_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MN093_00475"
                     /product="glycosyltransferase"
                     /protein_id="WP_113769552.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.1e-36,
                     bitscore: 121.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQLSIIVPIYNAEKKLDKCIKSILKQTFKDFELILVNDGSSDNS
                     LNICRKYEKQDNRIFVIDKKNEGSIATRRKGIEASNSNYIMFVDADDWIDKKMAEELYH
                     QSMESNADVTVCNMYKVLGNSMLIKKKNKSRYFSGNKIYDKSEIKRDIVVAYFWGHPFP
                     PSLCAKLYRKELIENSGKYLDRICFLGEDLFYNLEIFIKANRVKIIDKPLYYYRHGGFT
                     SKYMPHLFNDMVNGYKIQKEVIDEFYVDTKQIEYNGISIMLLNTFKTCLYNLFSSNLNT
                     SEIMQQIQQYVSNDNVIECLNNEGSLKYFSEEYLNAIKNKNIKYLYELGEQMYRKKKIK
                     KSFINFISKIPII"
ORIGIN
        1 gataattcat cagctcgtgc atatgctttt tctgagatat tcactctatt cagcgcctgg
       61 aatgcaagct ccacatcctc tttcggaaac agacctaacg ttgtacgcaa tgtagaatga
      121 tatccaaccc gcccagctaa tacattcttc agtaccgttg atcgcttcac aaggttaaag
      181 ctttgaaaaa tcataccaat atctcggcgc atgcgtcgta atccttttcc ttttgcagca
      241 gtaatagact ccccttcaat aatgatttct ccttctgtga tctcatgaag gcgatttacc
      301 gatctgagaa gtgtagattt tccagccccg gatagcccga ccattacaac aaactcacct
      361 ttttgaattt tcaagtttat attattcaat ccttttgtac cattcggata cactttggaa
      421 acatttcgaa actctatcac acatcttacc taccttctat gtattatcaa taactgaaaa
      481 acggcaaact aactgaaatc acacactttc cagttagtcg ccatttccat atgtattatt
      541 gcgttttcac tttctttcca tattcacgaa cgatatcaaa tttactatca tcagatttaa
      601 cgtatccttc atgtgagtat acttctttaa tgattttgtg cccttcctca ttctttccta
      661 tttcaatgaa agcatcctgt aatttcttgc tccactctgc atctaaatca gaacgtacag
      721 aaatcgtatc gtttggaatt ttctccgtaa atttcactat tttcgtttga tcgaatatat
      781 tcggataatc tttttttaca atattgcgag catcttggaa tacaacagct gcatctacat
      841 caccatttaa aagagcaata agtaactgat catgaccttt taatgtaaca ggtttcacat
      901 cctttagcgg atcgattccc tcttttaaca atacagccgc aggccataca taacccgctg
      961 atgatgttac atcttgatag ccaatttttt taccttttaa atcttttaca ctattaatat
     1021 tagaatcttt cttaacaaca aactctgatt tataaacatc tactaaatcc tttgtgggag
     1081 ctccagtttc atcatctacc ccaaaacgtt gcgcctgtaa aattacgttt gcagcctttt
     1141 tctcatgcgc taacacatac gctgttggag gtaaaaagcc tacatctact tgcttagatg
     1201 ccatcgcttc tacaattgta ttgtaattcg ttgaaatact aacttttacc ggaatgttta
     1261 atttatcact taatagcttt tccaatggtt ttgccttcgc ctctaacgta tctgcatttt
     1321 gagaaggaac aaattgaaca tttagtgtct tcggtacata accttttttc gtatcttcat
     1381 ttttacttgc acttgattcc ttcgttccac atccacttaa taatcccgct gctagtacaa
     1441 ctgttgtgct cattgcaaaa acttttttca acatgttaat gcctccattt ttcgttgtta
     1501 taaaataacc ttccataaac atgaagaaat atatcacata tttttacaaa taattgctta
     1561 tttacagaat ctttacacat tctatacatt cacattaaaa ttcttttcat atatttgata
     1621 tgattaattg aaagataact atagaaaagg tgaatggcgt tgaatccaaa tcaaattgta
     1681 actttaaata ttttattaac aagcgatgta catggtactg tgtatccaat tcactaccaa
     1741 gataactcca aagcagaaat tggtttagct aaaatttcta ctctcataaa aaaagaacgt
     1801 tctcaaaatg caaacgttct tctgattgat aacggggact tcattcaagg aacaccattt
     1861 acttatcatt acgctacata cgaaaaagat atggaaaacc caatgtcctt attagccaac
     1921 tacttagagt atgacattgc aattatcgga aatcatgaat ttaattacgg aatggatata
     1981 ttaaataatg ctgtggctac tgcaaattcc ccttatctat cagcaaacat tttagataaa
     2041 aacagaaaag aaccttattt cgggaaacca tatataataa aacatattga atcaaatata
     2101 aaaattgcta ttttaggggt gacaacgcat tacatccccc attgggaaca agcacatcat
     2161 attaaagatt tacaatttga agatgcattt gaaacaacaa aaaaatgggt ttcttacatc
     2221 cgtaaacatg aaaaaccaga tttactagtc gtagcctatc acgggggatt tgaacgtgat
     2281 ttacaaaccg gagtaccgac tgaagtttta acaggtgaaa accaagggta tgcaatgtgc
     2341 catgaaattg aaggcataga tattttacta acaggccacc aacaccgaga aatcgctcac
     2401 accgtgatta atggtgtaac aattttacag accggatgca atggacactc agttggaaaa
     2461 gtaacagtaa cattcgaaaa agcagaacaa aaatgggtga aaaaagagag ttattcagag
     2521 ttattgcccg tacaaggaat ttcggcagac caagatgttc tttccttggt tgccaattat
     2581 gaagagaaaa cacaaaattg gcttgataaa cctattggaa taatttatgg ggatatgcaa
     2641 atttccgatg ctatgcaaac acgtttgcaa gaccatcctt ttattgaatt cataaataaa
     2701 atacagatgg atatagctaa tgtttcaatt tcttgtacaa gtttgtttca taatacatct
     2761 ccaggtttcc cgaaacatgt aacaatgcgt gacatcgttt ctaattatat ttatccaaat
     2821 acattaaaag taattagaat aaccggagcg gatataaaag atgctctcga actctctgct
     2881 tcttatttca cattaaaagc agatggaacc atcatcgtaa accctaccta tatagaacca
     2941 aaaccacaac actataatta cgatatgtgg gaagggattt cgtatgtatt aaacatttca
     3001 aaaccaattg gagagagagt agagtctttg cagtataaag gcgctcctct taatatgaat
     3061 gaagaatatg acgttgttat gaataattat cgtgcaagcg gtggcgggaa cttctttatg
     3121 tttcaaaata aaccagtagt aaaagacata ccaacagata tgtctgaact tatcgctaac
     3181 tatatattga agcataaaaa gatagaagca acaaaaaatg aaaactggaa agttattaaa
     3241 taacaatttt aacaaataaa aaaagatggg ctatgcccat cttttaattt aattttgcat
     3301 tatcctgctt ttttaaagct tttaatttcg ccggtgtaac gtccgtgcct tcttcgttaa
     3361 cgactttaat tccttttaat tcgtttaaca tattttgacg aaatcctttt aaatattgtt
     3421 cacgaagcga ttggcgctca cgttgttctt cttcagttaa gccttcagct tttgcttttt
     3481 tcgctaagaa gttaatgcgt tcaatgagtt cttgacttgg catctcgaat cccccttcta
     3541 ctcaaaactg attattatca tacaatagtt attcctcttt atcaagcaat tgctttgtat
     3601 attctacata ccttcgatgt acagttgctt ttgaaacatc atgaccaaaa ccacgaagtg
     3661 ttgctgcaat ttcttcaaaa gttaattcat tccggcgcaa acgtacaatt tcctcaattg
     3721 gcacttcttt tttctcacgt cctacgctta aatgacgatt tttcaaatta ttttctggac
     3781 gaaatccttt ctccactgct ctttgcatgc cacgtttaat ttttaaattg tggatctttc
     3841 tttgatactc ttcaacgatc ccaattatat ttagcaccat cgaatcagaa tctgaaagct
     3901 gtaattcacc actatgcgtg tgcgtataaa cttttatccc ctctttatgt aaacaatgca
     3961 ttaatgcaat ctttgcattt cctctaccaa gacgcgtttc atcttgtata agtagtacat
     4021 caacttgttc atctcgaatt gtatctagca cttctaatat gccatcacgt tcaattgtat
     4081 aaccgctagc ctgctcctca attacctttg taacatccat ttgatagcgc tcagctaaat
     4141 gcaataattc atctttttga cgcaataatg atgtttcctg ttcttctttt gttgtgctca
     4201 cacgtgcata aataattgca ttcattttga acccttcttt ctcactatat tttccttata
     4261 gtgtatcata aatttgcctt tcgttcgaac ttatgtttgt agaatgtttt ttcgcatgtt
     4321 atacttaata ataagaaaaa tgaaagaaaa cgaggtgtta gaaaacatgg aaaagttaac
     4381 gaaacgccag caagacattc tcgactttat taagctaaaa gtacaagaaa aaggatatcc
     4441 accttccgta cgtgaaatcg gtcaagcagt cggccttgct tctagttcta cagtgcacgg
     4501 acatttatca cgactagaag aaaagggata tattcgacgc gatccaacaa aaccacgcgc
     4561 aattgaaatt ttaggtgaca accgaacgga aacacaatct gttattcaag ttccaatcat
     4621 cggaaaagtt actgccggtt taccgattac agcagtcgaa agtgtagaag atcacttccc
     4681 acttccagct agtatcgttg ctggagcaga tcaagtgttt atgttacgca tttctggaga
     4741 tagcatgatt gaagccggta tctttgatgg tgatttagtt gttgttcgcc aacaacagtc
     4801 tgcatacaac ggtgaaattg tagttgcttt aacagaagat aacgaagcaa ctgttaaacg
     4861 tttctataaa gaaaaagatc atttccgtct acaaccggaa aactcttcac tagaacctat
     4921 tattttaaaa caagtgtcag ttattggaaa agtaattggc gtatatcgtg atttacatta
     4981 aaaataataa aaagaagata attcccttat ttatataggt aattatcttc tttttatatt
     5041 ttgatagatt tccgttcatt caaaagaatg cgtttcatta attattaacg cgtttcaata
     5101 gtaacatctc cagcagcggt tttaccgcta atctttttac taccattacc aatcgttata
     5161 tttttattgt cttcattaaa aattgtcacg tctccagcag cagtttgccc agttataact
     5221 gcatcttgtg gtttttccaa taaagtaata tctacatctc cagcagttga acttacctct
     5281 aaatcatatt tagaatcatg atcaataata tctatatccc cactagccgt ttttgctgtt
     5341 actttcccta ttactttttt aaaattcacc tcaccagctt ttgtagaccc ctccacactc
     5401 tttgctgtta catgtttcaa atccacttct ccggcgagtg tttcaacact tacgcggtca
     5461 cttttcacat tacttatttc tatttgtcca gcggatgaat ttacttttat ctcttgataa
     5521 gaacgttcag gtactaatat aggcaatgta ggcgtttgaa atccgaaatt gtaaaatgaa
     5581 aaatcaaatg aaacaccttt ttctatttcc cctatgattt ttaatgtatc accatcttca
     5641 gcaatacgaa tctcctgttt acttacgtct cctttttgct ttacataaaa agaggaatca
     5701 ggagattttt ggacaacaat atctcctgca tctaacttaa cttctacatt ttttagcgtt
     5761 tcgtttttaa ttacgtcctc tttatctcct ttttctgcag tttgtactgc tttttcatat
     5821 gtttgtgaaa tccctattac tccaataatg atacaagcga tagctactaa taatatcttt
     5881 ttcatcatct actccccttt tatcattttg aagttccaga ctacatagcg tacacataat
     5941 cttttaaacc acttcgtact ataataagct acaatacata acaacaaacc tactccgaca
     6001 aacgttatac taacgaaaag atccaaccat ataaaagtgc ccataaatac ttttacaata
     6061 acgaaaaatg gtgtcactac actagcaatc ccaccgaccc aaaaggaaaa tataaaagct
     6121 ataattgcaa ctaacgggcc taacacaata ataaaattaa acaaactaag tccaaccgct
     6181 gccatgacag ctcttgtcac atttgaagtc gacggatctt ttttcatttc atcaaatcga
     6241 tacatcgcaa gtaagtcttt cgcaattact ttcggagagc caagtccctt tattatttct
     6301 gattcagttt tcccctcttc catcccaaac tgaaagtgct cttcataatc aaataaaata
     6361 tcttgtcgct cttcttctgg taactttcta agatgacttg ataattcttt aagaaactgc
     6421 tctttactca tcccattcca ccccttcaat aatttcttga acacctttag caaaatcacg
     6481 ccactctgtt actaataaag taagttgcat ctctccttgc tctgttagtt gataatattt
     6541 acggggcggt ccttccgtgg attcttttaa atacgtttga aaatatccct ctttcgttaa
     6601 acgacgtaat aacggatata cagaaccttc cgatattaaa aatttattag agatttgctg
     6661 aacaagttca tatccataac aatccttacg ttttacaagt gccaatacac acagttctaa
     6721 cacacctttt ttaaactgaa cgttcaagga caatccccct ttctcatttt agtactgttc
     6781 aatacacggt atctgattta tccataatat accactcagt actatttatt gcaaggtact
     6841 gaattatatt tattccctaa atttagaaaa agcacaaata aaaacacgaa taagatcctg
     6901 ttgtaggtga tcattattcg tgcttctatt cgattcgaac tatattaaca cagagcttca
     6961 ttcaactttt ctcctctaag aactaacttc tacttgttta cctaataaat tacgaaatac
     7021 tcctttcctc tctcgagcta gttggttaaa cgctccttgt tgaacgacct cccctttatc
     7081 taatacgata acctgatcag cgttacgtat cgttgataag cgatgggcaa ttacaataat
     7141 agtcatttga ccctttaact tttctaatgc actttgaatt aacgcttcat tttctgtatc
     7201 taacgaactt gttgcctcat ctaaaactaa aatagagggt tttcttaaaa ttgctcgtgc
     7261 caaaactaac cgttgccttt ccccgcccga aagcctaact cctctgtccc caataaaagt
     7321 atcaagcccg tttggaagcg ttcgtacaaa ttcagcagca gcagcaaaat ctaatgcagc
     7381 ccaaatctga tcttcacttg catttggctc aatcatcaat aaattttctc ttatgcttgc
     7441 attaaataag aatggatcct gctgaacata gctaatagat ttccttaaag ccaataaatt
     7501 atcacttgta atagtcgagt catctagtaa tacctttcct ttttccggat gaacaagtcc
     7561 catcaaaata tcaattaatg tactttttcc agcacccgat cgtccaacaa tagctgtcat
     7621 acaattggtt gggatttgca aattaatatt tcgaagagcg tatacaggtt ctttttgatt
     7681 gtaacggaaa tatacgtttc ggcattcaat cccttttttt atagacattg gttttacata
     7741 tttatagcat tgttctatat cttgtaattc ctctgctttc ttacattcct cttgtaattc
     7801 tattaaagac ttaaaagcag gaatacttgc agctagttgc tcaagattgg attgaatgct
     7861 tgtaaatctt ggccatagcc tagaaaaaat aagaataatt aataataatt gtcctggctg
     7921 agcttggaat agttttatag atgtaaaaat aagaaatgca attaaaatag acgatgcaat
     7981 tttataaaaa agttgcgaac tattttttaa tttcataaat gctagttgtt cttgctctat
     8041 cctttggcac caagtatgta accatgtata tctagattct tctaacgtat tgcttttaat
     8101 atctttaatc ccgttaaaat ggtctgttat gcctccaaga taacttctag ctacctccga
     8161 tttttgatta ccaagcgctt ttgatttttt tataaaatgt ctagaaaaaa aagcaagaac
     8221 taaaccagca aataggacaa agagagttat cgttgcagaa agccataaag caattccaac
     8281 ttgtattaat gtaaaaataa gagccgttaa catctgaaaa aataagtttg ttccattcac
     8341 aacacgtcct aattcttcag tcaaagcatt gattaaatcg gattttctct tttttacaaa
     8401 aaaagcccaa ttagcttgta ataaagtacg atatatttcc aatcttatat ggtttgtaaa
     8461 atttataaga attttcatat ttcgaagggt aagattttgt tgcaagaggg attgagctac
     8521 taccaaaaaa atataaacac ttaagataat tagcaagctc aatgtttcag ggatattatg
     8581 caggaattca aacacctctg aacctggagt tgaaccgcta tttaccttta caactccact
     8641 gacacttatc ataggaatta ataaaagaat gccaatcccc tctaaaaggc taaccaagga
     8701 cattcctaat aaatttagat ataatgtttt tccagaaaaa gaatgtaact tcttagcaaa
     8761 gtacaagaga ttttccattt ttatgtcccc cctatgataa tacatgcttt ctcgctttcc
     8821 tccaggtaca tagaatagga cgtaaaggaa agtacaaaaa atgaagatac ttaggcaatg
     8881 gtaacgtctt tgcatcaatt ggataaggat aaaagtaact aataataaat aaaatttttt
     8941 gttgatttga cattaatgaa aataaatgac gactgtgata cgccgctact tcatctggaa
     9001 caggatccgt atgtaggttt atcatttttc taatataaaa tattgcatct tgtgctaatt
     9061 ttctggaccg tctttgacct gccaatactt tcatttcttc agggattgtt gcatttaaaa
     9121 gctcagtagc tagaattagc gcttggcctc ctacatgccc acattgatat gttgtgaata
     9181 acttgtaaac ttctttccaa tcaagtcctt gcttgaccat ttgatttata tctaataacc
     9241 aacgcagtcg agaccagcca tgacgtgccc catgagaaat aagaaataaa aacaagtctt
     9301 cgcttcctaa tagatatata gggtaacttg taagcgtgct tgttcgtttt cgctcccaga
     9361 gttcctcaaa gcttggctcc ttccctggtc cagggtgtaa tctccaatga atttcaattt
     9421 taatttgctt ttgcggatga aaaaattcca tatgatgatg tctccatttc caatcattta
     9481 atattgtttg aatatcacca tcctttacgt aaccttgttc taaaagaagt ttttctgctt
     9541 ttttcagctg ttgaattgga ataagaacat ccaaatcaga ggatgttcgc aaggaaatat
     9601 ccccatatag gtcatgagca agtagcggtc cttttaaaaa aagagtacga atctcatttt
     9661 cagtaaacag tttacttact agctccattt cagcacttaa atgaagcatc tgaaatgtat
     9721 tcattttaaa atattggtgt aaaacttgaa taacacgtac cggaaccaat tttttatcca
     9781 tctctttcat ctttggatat atgaatgaat atacacgatg atggattgtt agttcgagaa
     9841 atctatccca atcaatattt tcaaaccact ccttattgat ctcttgtaac tccgtagcat
     9901 ttccactttt tagaatttca agttgcaatt ttagctcctt agctacaccg tttaaatcca
     9961 gtccataact gttattcata gtattctcct tcaagatttt ttaaccaatt attctcgcaa
    10021 atttgctaac tacagtgaac cgttccattt cttctgctcc cgttatataa aaaggaccac
    10081 tacgtaacca agcatgagca accatctttc cattcttatc cttcgcggtc cctaaataca
    10141 gagtactctc aatttgacgt ctttttagca tttccattcc agctatcgca ctcacaagac
    10201 atttactctc ccaaaaagtg tgctgactca taatatgtat tgcttcagaa atacttctta
    10261 atattaattt attagattcg ttacagctta aagatgtttc atccatatga gtacctaatg
    10321 taggagcaat cttagaaaat ggcataaatt taagaaaacg agcccatcct aaatacatat
    10381 acgcttctat aaataaaaac attgttttca tatctaacga gaaaaacttt cttatctttt
    10441 gcacaatatt catatattcc cctacttctt atacaggata aaatactaga ctacttgttt
    10501 ctcccttcta caatctcaac caaattttct tctaacaaaa gttctaaaaa agaaataact
    10561 tgctcctcac atgtagattg ctctacttca tattccgcta ttaatgaagc aactaattga
    10621 gtaacagatg ttggggtctc aataaaatcc catatcgttc cacccatttc acctaaatta
    10681 taatattttc cattttgaat actcaacatg actttttctc catccatatt actgacgatg
    10741 tttccttttc cttgcacgat tgtatggtat aataaaatgt tttgttttcg aatcatagat
    10801 tactcctcct tatttaaggt tgctagaact aaagatacta gttgatgcgc tgtaaattcg
    10861 caagttggtc ggcgtagtcg aaaaatatca atttgttcga tgatccttgt agaagtacta
    10921 aaatgccaat ccattaatcc caaacgtgga atcagaaaat ttcgatatga atgacggaat
    10981 aaagtatgga gacgctcaag tctttgaata ggataaatat caattccctc tctctcagtt
    11041 ttaactaatt caaatacacc ggcaaggggt aatgtttcag ttgaaaattg agaattgact
    11101 ggaactgcat atttagtttc acgttcaaat aaagaacaat attgacttga cttcattcca
    11161 aatgcggtta gggtttcctg ccatagcttt tgttgtggat aggctgaaaa aacaagcgga
    11221 acatgaccat catttgaaaa agacacagct atcacatcat cacttagcag ctgatatccc
    11281 ttacttaaaa aagcagtagc caaagtagat tttccagccc ctgaatctcc aataaaagca
    11341 taagcctttc catttatagc aatcgcactc ccatgtaacg gtaatattct cctttgcatc
    11401 aatatagtgc ccatacaagt ccccagaatg taaatcctaa tctcattttc atcagcttca
    11461 ttcaccggag acacactaat tctatttcca tcccttatag caaacgtagc aagattaggg
    11521 agttgaaaca taactagatt atccctcacc aaaaattgat tgggttgacc tgctatttcc
    11581 aaccataact cagataaatc atcaatcgta atcaaaacat ccggtttatc ggattgttta
    11641 tttatttgag gtaattctgg taaaatgatt tcacttaata aatttaatcc aaaagcttta
    11701 taaatatttt tttttacagt atgagtattt atcatttata tcactccaaa ttactaaaag
    11761 aattaattta aaggaaaagc ccttatcctt tttcatatgg tataagggca acaaaacatc
    11821 caaaacaaat aaatttatga ctgatgatgc ggaccagtcg caggttcacc attgtaagct
    11881 tcatcatgat agccctcgta tcctgatgcc atagtcattt taatgtccaa tgtctctagc
    11941 accggagttt tccactcttt tttcatattt tcacctcctc tcaagaaaag ttttttataa
    12001 atcgactaac gactaaactt cgaatagcaa tcctgtattc tgggtttgtt gcatattctg
    12061 gccggggtcc ttccctaacc tttgaaatag ctgactttac cacttgctca tttaaaaatt
    12121 cccaaatcca cctctctgaa ctaaggcact gaagctcctc aacaaatata tgccaagaag
    12181 gcgtcatgcg atgaacccaa tctacacctt gaacccctct ataatgctgg ttcaatctga
    12241 ctttatccgg caaaaaactt tctgttgccc tacggataag tgctctgtca aaaccatcct
    12301 gtacatattg ttcttcaggt actgataggc aaaaacgaat cactcgtata tcatttgttg
    12361 gatctcgttt ccagagcgaa tagcgtaaag attgtttagt tccaagtgta tttgttgcat
    12421 tccaatggaa caattcttca aaatgtcttc ttctttcttc atatatattt ggcaaagttc
    12481 ctccctcatc aatgccatgt tcttttagtt tcgcgaacac atcagtcctt tttgacagct
    12541 cggagctaat taatctaggt gaacgatata tttcaatgcc cggagtgatt ttattaataa
    12601 atgggaatgc aaatttccaa atatatgata aggattttgt ttttttcact ccaatatttt
    12661 tactatataa atctatttct ttataaaggc gaatccacct taattttttt aaaagaatgg
    12721 cataatactc tatagcaggc ccccaagata cggataaatt cccccttcct ccggttaata
    12781 atatgcctat cccttcctca tgtgctttct cgaaaattcc ctttatccaa atagaatttt
    12841 caaaaaattt atacggcatc tccatcattt caagaaaatc atttatctct aataaaggat
    12901 tcccttcttg aaaatctaca aaatgatcta taatcccttc tatatgctct acggtcgatc
    12961 gaataaacgg cctctcgtta gccatcctat acttgggtgt aaaatcaata aaatcactag
    13021 gaggaacata actatatgta tgtagtcgtt tattctttgt acgtaaaacc tttgctgcaa
    13081 agctgacaac agatcctgaa tccaatcctc cactcaactg ggcaccaaca tggcgatatg
    13141 ttcgtaacct tgctgtcact gcatcttgaa atacgtcctg gaatgcctct acatattcct
    13201 catttgactt tagctttaac ttttctcttg aagttaaagt acaatacctc ataagcatta
    13261 tcttatctcc aactatcgaa atactatgag atggaggtac ttgttctata tttttataag
    13321 gcgtcatggt gacatcaact acatcaacca ttccacatat agctaaatat tcagcgagcc
    13381 attgttcatt taattgtttt tgcacatacg gtaaggtcaa taacggctgt attgtcgtac
    13441 aaaacgcaaa tcgctgttga tccttgtaat agtaaagagt tcgactccca gaaaagtctc
    13501 ttgctccaaa caatttttgc tgtcgctcat cccaaatcat aaaagcaaaa tcgcctacta
    13561 aatactttgg aacttcttct ccccaccttt cataggagag caatattaat tcgctgtctg
    13621 tcattttttt tctatcagca taatccactt gcagtcttcc aaataactca tcacgattat
    13681 cgataatggc atctgctgta atcgctaatt gtctttcata atcataaaat ggtaattgtt
    13741 caccgataga ctctggtgtt atccattgtg cgtgacaccc aaggaaaacg ttatttgtgt
    13801 gccatatttg aacatcgtca gcaggatatt tttgcaaatc attcattaat ctcgcaccgt
    13861 gctcaatcga tataggttca tcatcaaaat gtaaaatccc agttatagca ctcatttttc
    13921 ccctcccact atgcaacaat aagtaaagcc caatcgaatc aagtaaaact ctcatcagct
    13981 taacttaatc attctccact gataattgct tctcacgaat tgggctttac agacagttcc
    14041 tctacaacta catatatttt gttgctcttt ccacattctt tttaaagaac acttatattt
    14101 agttcaacaa aaataccaag taaatatcta tagtttttat taactttttt caatatatag
    14161 ctgtagttta ttcttattaa agaagggcat tattaagata aaattaacat ttcatcttta
    14221 ctctgtcaat caacagactg aatattctgg ttacgtttaa ttagaaacct ttataataaa
    14281 cttccctact tattctttaa ccttgtccgc aagtatggat attttctaca ccaccttggt
    14341 aaactaggaa aagttaaaac actatatctc catacatctg atcttgcttt atttaaatca
    14401 acagcgtagc tatctgtaat attataaatg agctctcgtt accctcttac ttcctctaaa
    14461 atatatgccc cgatagtgtt tatttttgtt attgtaaaat tttcattatc cataataatc
    14521 cactcattat caatttctac aatattcatt ttttgtacat tcggacttta tactcatgat
    14581 atcaacttcc aaaagctatc attttttaaa ataacgaaac taccagctac tcttattcgt
    14641 atttaaccca atttcaaaag taatcattca aataaatgta cctcctaaat ttacacataa
    14701 catccagaca acgttttatt ttacaaagca tttttgatac attgaattac cctttgtagt
    14761 tccctatctt ccatgttaga actagaagga agacaaatac cttttttaaa taattgttca
    14821 cccacatgag tatttccgct atgagggtaa tatttcattg tttcaaaaag cggctgcata
    14881 tgaagcggtt tccaaacaga gcgagcttcg atattttctt tggctaatac tcccaatagt
    14941 gattctatag atatacctgc ttctttttca tcaatcgtta aagttgtaag ccaacgattc
    15001 gagcaagtgt tttctaattc gggcataaac tgaaacccag atatattgga taattctcgg
    15061 taatattgct caaatatgaa ccttctagcc ctaactcttt cttctagcac ctctaattgt
    15121 gctcttccaa caccggccaa tatattactc attcgataat tgtaacccat cacactatgc
    15181 tcgtagtgag atgctaagtc tcttgcttga gttgctaaaa atcgcgcttt ctgtaatgcc
    15241 tcaacatcat cagaaaccag cattcctcca ccagaggttg taataatctt attgccatta
    15301 aatgaataaa ccccaaattt cccgaatgtt ccacttgctt ttcctttata tgtagaaccg
    15361 agagattctg ctgcatcctc aataacggga acatcatatt cattacataa tgaaagaatt
    15421 tcatccattt tcgcactctg cccatataag ttaacaacga taatagcttt tggtaatttc
    15481 ccttctttat ccgcatcaca taacgcacat tccaatgctt gaggtgacat gttccatgtt
    15541 tccggctctg aatcaatgaa tattggttca gctcctacat aaacaattgg atttgcactt
    15601 gctacaaaag taaggcttga acaaaatact ttatctcctt tttgaacccc taataaccgc
    15661 aaagccaaat gaatagcagc agtgcctgaa ctaaccgctg cagcatcctt tacaccaaca
    15721 aaagttgcaa gttccttttc aaaagcatct acattcggac caagaggagc aatccaattt
    15781 gtatcaaatg catcctgaat atatgtttgt tcatttccgc tcatgtgcgg tgatgagaga
    15841 taaattcgtt tttgttgtat cattaccatc tttatcaccc ctagtaactt acttcattga
    15901 taactttggc aggaataccc acagcaatac acttaggcgg catatcattt atcacaacag
    15961 ctcctgctcc aataatagac cattctctga ctttgacact tggaattata gtagctgcgg
    16021 cccctatatg cgctccttct tctataagga cagaacctgt aagtgtagcg cgaggagaaa
    16081 tatgcacaaa atcacctatt atattgtcgt gctcaacgac agaacctgta tttataatgg
    16141 catgattacc aatttgagta tcagcattta tcactacatt tggcatgacg actgtgccgt
    16201 ttcctacctt agcacttgga ctgacaacag ctgttttatg tattaacgtg atgtaaaatt
    16261 cgtctgataa acataatttt ttgacaattg cctttctaac tttattattc cctatcgcta
    16321 taacaaaatt tatttgatga aaataattaa tcatatcgta tgcagttgaa atcggcccaa
    16381 aataaagatt atctacagta actatatttt catatcgatc atctaaatat ccaacgattt
    16441 catattcatt gtttgataaa atactatcct gtatgacctt actatgaccg ccgtgtccaa
    16501 taattgcaat tttcattttc tctccccact tacagtcgat tttgcacccg taaaaggctc
    16561 cattgttaca tgaccaactt ggtttattcc ttctgattta agcactttta ttactgtaag
    16621 aaataatatt ttcatatcga gtgaaaagga ttgattattt acataccata catctaatgc
    16681 aaattttttt tcccaagtaa tcgcatttct cccattcact tgggcccacc cagtaattcc
    16741 tggttttaca tgatgtcttt taacttgttc attggaatat aaaggtaagt attctattaa
    16801 caatggccgc ggtcctacta aacttaaatt accttttaca acattgataa gctgtggcat
    16861 ttcgtctaaa ctgtatttcc taagaaattt tccaaatgaa gttaatctaa cttgatcggc
    16921 taacaactca cctttactat ctctcgcatc ggtcattgta cgaaatttgt aaagataaaa
    16981 agcttttcca tataaacctg gacgctgttg cttaaatata atcggagatc ctaacttaat
    17041 tctaactaat ataaccacta taataatagg caatgagaga actaataaga atgacaaaga
    17101 aactaacaaa tcaaaaaatc tcttcatata taattatact cctcattcaa actttttagg
    17161 aagtcttcct aaaccatgtc aatacaatat ataaaagaaa ttgctaccgt ttctcttcct
    17221 ttcattacaa aaacaaatac cttatataga ataaagatta cttaaattta agtacctgtt
    17281 ttctgccatc aagtacttcc aaatcctcat taaaaacgta agtatgagta cctttgttcc
    17341 tcttaaaaat acttggagta atctctttaa ttttcttttc tctatatgaa tcttcattaa
    17401 gtatttcgat ttcattcaaa ttgactgaat atccataaga aaataaacag ttttgtgatg
    17461 gtctaattaa tttaccatcg tggacaaata tattcccagc aggtcgagcc gattttgcat
    17521 cagaaactat aggattcatc ggatgcgaca cccattgacc aaataaagaa tctgaatgaa
    17581 ataaatataa ctcatcaagt gagcttccat cagtaaaaac gttagtaaac aaccaatact
    17641 taccttcatg ttgaataatt gttgtatcaa cagcattaac attctccatt aatacttttt
    17701 caatttccca ctcatatgga aaattagtcg ctttatatag ttctattgtt tgattacttg
    17761 acgtctcagg tatcatataa atctctccac catcttttat taagaaagga tacgataaat
    17821 gatacggttt ctccaacaca gtagtcggtt gtgaaacgct atttgattca atatccactt
    17881 cgacgaacgc aatattcccc ttaccctcgc tatatatata atcttcaaaa aagatgaaat
    17941 ttctttcatt tctttcaata acaaaaggat ccgcataaaa tctacttaac ggggctttaa
    18001 taatatgaaa tctactacgt tcctcttttc tatttttaaa tgctataaac caatgttcca
    18061 taaataacct ggattttaac ttgtgcatag caagtcgaga aataaaagga atcatctgaa
    18121 aattcgtcgg atatttatct gggcgctcgt taaccaatga aggttgatta tatgtatcta
    18181 agttagtaat atacgaccat ccttttttgt ataaatcaaa gagccttctc aaaacaatat
    18241 ctttaacttt ccaatacaaa agattgcgat taaaaaataa agactcaaca ttcagtggcg
    18301 atatcgttct ataaataacc ttgtgatttt caggcttact cgctaaaatt tgcagcctag
    18361 tttctagcgg tatcttcctg ctcgccatct cccaaaaggc ttctactcct tgtccactaa
    18421 agcagtatga ccatattcca tatcttgcta tatttataat ttcaccatga agtgtaccaa
    18481 atcctaactt tataatcaca tctaactgtc cacctctaat tacatctaaa tctgaatcag
    18541 aaaactcatt ctgtaaccct tgtttgttag gatatatggt taaaattctg cagccatatt
    18601 cagataacaa agattccata tgaaccggtt tcaatgcatt atgtctaacg tatttactat
    18661 aataattata gtcccacttt aaatatttag aatacaatga cgtcttcttt acgctttgct
    18721 gaaaaacatt ttgcttctct accctttcat taccgttgat aagcactata gagagctcca
    18781 aaaattcagt atgaacaata tcataaatca ttttctcaat ccaactacta acaacaagtg
    18841 aatctaacat gataccaatt tttaaacgat gctgtctatt tgcatttaac atatcatagt
    18901 ctcctacctc tcagtagtta attttcacat ataatccacc gaactagttc gtttgtaatc
    18961 ataaaggtta caaattccac cctagcaact aacattctgg acagtcttat ttgtgatata
    19021 cagtttgcct aaaacttcat agatttttac gtttaaaaat aaaaaacagc tcaatttatt
    19081 tattgaactg ttttcagtag atgattttat atattcagtt aattcatcac acccaaatgt
    19141 tttgtcaaat agattatttc aagcaaatag atttatgtta ataccacgtt atctatcaac
    19201 agcgtacttt tcgttatatc agtcgaaaca ttattgaata tacatcttgc tattaccatt
    19261 gttttttctt tagttaacca atgtaaagcg attgatgtgt tttcaagata tgaaagggta
    19321 ataaccgaaa tattttcatt gtctactttt ctaataatag agttcaaaaa tgtacttcga
    19381 gtgtttagca catttccatc aaaattcaag gcaacatttt gaaatgtaca attatctata
    19441 tttacctttc tattataatt tacatcatta gaacctagaa ctatatctcc acctattctt
    19501 gaagttttta ttttcataaa ttttccacca cttatattac agcactctag ttgtgcagga
    19561 ccttctatta cagttatccc ttccactaca ttaggtctac ctacgtagtt ttcaggtacc
    19621 ctaattgcca aaccataatt tttgactgtg aaatttttaa taactccccc tgttaatgta
    19681 atatcaacac caccatctgc tgtactatca ctccattctt tttcaagcat aatatcagaa
    19741 atataacatc taccataatc atatctacta atattaaatc ccggtgtacc cccatctgtt
    19801 atagttactg gtgttccatt caatacttca gacacttgaa aacttgttgc tgttacattt
    19861 atcgtgtaat aaagcttatc cacactaatt ccggtaggaa ctttaccaac ccactgctca
    19921 aaacaaactt tagcaccatt tcccattcca tgaggcttac taaaagtaaa tgtactagtt
    19981 gtaacatcta ttacaggtgt tccaaaatat cccaaagaac tataaccata aaataaacca
    20041 ttctttattt gacaattctg aaccactgca ccttggacat ccattaattt tatattaccg
    20101 ttattacaga caactccgtt aacaaaatta tctcctttaa caacaaattc acacccgatg
    20161 aatgtattat taaggtattt tacataccag ttattttgat acgaactaac tcctccaaca
    20221 tttggacctt caaacgtgtt attttctaca atcacattta taccatcaac atttacaaaa
    20281 tgccctctag cattatcata tatataattg ttaaaaatat atattctagt attcaattct
    20341 agtcctgact tatttaactc cggccgccat gttggtatat tagtttcaga ccacatagat
    20401 tcaatatcaa taccgaacat tggggcagta ccatctaccg taacgtcatc atcagctttt
    20461 ccaatatggt gtattttatt atttgaaata taaatatcat ttgagccagt gagagaaatc
    20521 ccttgtctcc tacaatggtg aagattacaa ctatgaatat aaatatacga tcccatgtcc
    20581 tcttggatat aatcagacga attaagctta tattctagcc aagctgtagc aatggcatca
    20641 ccagtacaat cacttatttc cacattatta attacaatgt tgtgtgagcc gtttatttgt
    20701 atgccttgtc cccactcatg agtccaattc tgattatcaa ctttcgcatt aatttgtgca
    20761 atttgagtat cacttaacgg tgaggacgtt atatcaatta caaaaatcat tttattagca
    20821 tcttttatag gtgcgaacca ccctcgacca gttggactcg ttggagcaaa tccaccatta
    20881 ttcctaaccc caactaaagt actattagaa ataatatctt tatactggta aaagctatac
    20941 cctgtagcaa ctacaccagg gatagaccac aagcgaaaat tttgtaaaag gccagggttt
    21001 tcatatctat ctactatttc actacgaata aaattaggat tactatttaa tgagccatcg
    21061 gcgtttatcc ctccccttac aaacttcact cctaattcat acttatgtgt ctttttatct
    21121 ccaactattt tcccaccaga aatcttaaca tttttaacac ctttcactcc aaatatacta
    21181 taccaaggag atgaattagc ctctaattct aatatgcatc catccatcat ttcaaaatac
    21241 atatcacttt gcagaactat acacgtgaat gttatcggat caatcttcag cttatatgtg
    21301 ccgcttgaca atactacgtg attatatcct tgagatttag cccaaactaa cgcatcattt
    21361 atcccttttg tggtttcata tgaatcggtt ccatcacttt taatattcca tctatctaat
    21421 tccaatacgt aggagcttga aacacttcct gtcaatggaa atgaaagtac tttgggaatc
    21481 cacttcgatt ttgcactatc ataaactaac acgtcattat gagtaggaaa cttggttgtc
    21541 aaatctacat catcaagatt aactcttata gacattttta atttacaccc ctttattact
    21601 tttatatatc ttatgtaata agggatgaaa tagattagat ttctttatag ataaatactt
    21661 cattttttat ctctcttatt aagtttgaat agtacatatg ctaaattata ggaattttag
    21721 atatgaaatt tataaaagat ttttttatct tcttctttct atacatttgc tcacctaatt
    21781 catataaata ttttatattt ttatttttta tagcgtttaa atattcttct gagaaatatt
    21841 ttaaagaacc ttcgttattt aggcattcta tgacgttatc attagaaaca tattgttgta
    21901 tttgttgcat aatctcagac gtattcaaat tactactaaa caaattgtat aaacaagttt
    21961 taaaagtatt gagtagcata atactaatac cgttgtattc tatttgctta gtatctacat
    22021 aaaattcatc aataacttcc ttttgaattt tatagccatt gaccatatca ttaaataaat
    22081 gaggcatata tttactagta aatccaccgt gtctataata atataaaggt ttatcaataa
    22141 tttttaccct gttcgctttt atgaatattt ctaaattata aaaaaggtcc tcacctaaaa
    22201 aacaaattct atctagatat ttcccactat tttcaattaa ctcttttcta tataattttg
    22261 cacataatga tggcggaaaa ggatggcccc aaaagtatgc cactactatg tctcttttta
    22321 tttcactctt atcataaatc ttattcccac tgaaatatct acttttattc ttcttcttaa
    22381 ttaacatgct attccctaag actttataca tgttacatac agtgacatct gcgttactct
    22441 ccatagattg atgatatagc tcttcagcca tcttcttatc aatccagtca tctgcatcaa
    22501 caaacattat atagttagaa ttcgaagctt ctattccttt tcttctagtc gcaatactcc
    22561 cctcattttt cttgtctatt acaaatattc tattatcttg tttttcatat ttcctacata
    22621 tatttaaact gttatctgaa gaaccatcat ttactaaaat caattcaaaa tctttaaatg
    22681 tctgcttaag aatagatttt atacatttat caagtttttt ctcagcgtta taaataggta
    22741 ctattatact tagctgactc ataaacttct cctctctctt tacttaaaac atttcttatt
    22801 tgcgcctctc ccataattaa acttaaagga actaatttag gttttatgat gtattattaa
    22861 aatctgcttt attataaata tgaaaatttt tacaataaat ttaaaaaccg ttatgctatt
    22921 ttttgtacat aacggctttt ctcttttata taataattat ttttaacata tttactcata
    22981 atacaccttc tccttattct agatggagct caaaatctat atttcctata tttaagcaca
    23041 actttattga ttaaatttac tcaatatata tctaatcttt tcaaatttta tacattactg
    23101 tccaccaata aacttttcga ataatctaat attttcttca taaataaaga actctcttcg
    23161 ttccttactt ttcaatctat aatactccat caagtccgga tctgataaca tattttttag
    23221 tccctcgtaa atcccattct cgctattttc gactaacaat ccatatttac cgttatctac
    23281 catttcagcg gatccattac aatatgtgct tagaattggt agttctaaaa taatcgcctc
    23341 agcaacagat aaaggaaacc cctcggttaa cgaggaggag acatacaggc tacacctatt
    23401 catgtattta tatggattgt ctttaaatcc taaaatagct attttttcac ttagcatagg
    23461 ggttttcaaa atcattttat ttaaatttac cttttcggga ccatctccta agattattaa
    23521 attaaagtca tagccttcgc ttaataacct cttacaagaa tgtattaatc tatcgacacc
    23581 tttttcaata cttaatctac aagaacaaac aatgtttata ttattcttaa agtcataatc
    23641 gaatactgtc tgattagata atttagttat ttcattagta ttaataggat taaataatac
    23701 atagcatctt tctttcagat catatttgtt accaaacctt tttctggcac cattagttaa
    23761 cataattatt ttatcaaatt tgctgtaagt acgtttttga atccatcttt taaatttaat
    23821 aaatatggtc gatttttcag tttcaagatg ctccaatcct ccatgaatcc acataacctt
    23881 atgacatttg ttaactctaa ttggataagt aaaaa
//
