LOCUS       NZ_CP092907            27848 bp    DNA     circular CON 07-APR-2024
DEFINITION  Enterococcus faecalis strain LJX 0909 chromosome, complete genome.
ACCESSION   NZ_CP092907
VERSION     NZ_CP092907.1
KEYWORDS    RefSeq.
SOURCE      Enterococcus faecalis
  ORGANISM  Enterococcus faecalis
            Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2812373)
  AUTHORS   Liu,R. and Fan,W.
  TITLE     Metformin significantly reduce the alkali resistance of standard and
            wild E. faecalis in normal and high glucose environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 2812373)
  AUTHORS   Liu,R. and Fan,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-MAR-2022) School and Hospital of Stomatology, Wuhan
            University, Luonan Street, Wuhan 430075, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unlcycler v. V0.4.9
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 255.1x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022557275.1-RS_2024_04_07
            Annotation Date                   :: 04/07/2024 08:03:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,843
            CDSs (total)                      :: 2,765
            Genes (coding)                    :: 2,717
            CDSs (with protein)               :: 2,717
            Genes (RNA)                       :: 78
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 48
            CDSs (without protein)            :: 48
            Pseudo Genes (ambiguous residues) :: 0 of 48
            Pseudo Genes (frameshifted)       :: 24 of 48
            Pseudo Genes (incomplete)         :: 17 of 48
            Pseudo Genes (internal stop)      :: 16 of 48
            Pseudo Genes (multiple problems)  :: 6 of 48
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 15:20:35
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 814385
            Orig. end                         :: 842233
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP092907.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27848
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="3"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..27848
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27848
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:17848](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17848
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    289..305
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 29.31"
                     /tool="antismash"
     misc_feature    complement(289..305)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 26.37"
                     /tool="antismash"
     misc_feature    complement(429..442)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.86"
                     /tool="antismash"
     rRNA            618..2178
                     /db_xref="RFAM:RF00177"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="MK744_RS03900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="MK744_03900"
                     /product="16S ribosomal RNA"
     gene            618..2178
                     /locus_tag="MK744_RS03900"
                     /old_locus_tag="MK744_03900"
     misc_feature    complement(742..757)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.58"
                     /tool="antismash"
     misc_feature    1029..1042
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.26"
                     /tool="antismash"
     misc_feature    1362..1371
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.53"
                     /tool="antismash"
     CDS             1556..1630
                     /gene="allorf_0815941_0816015"
                     /locus_tag="allorf_0815941_0816015"
                     /protein_id="allorf_0815941_0816015"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTGARTSGGACGLIRSNAKNLTRS"
     CDS_motif       1556..1585
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTGARTSGGA"
                     /locus_tag="allorf_0815941_0816015_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       1586..1630
                     /prepeptide="core"
                     /locus_tag="allorf_0815941_0816015_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.80"
                     /molecular_weight="1478.7"
                     /monoisotopic_mass="1477.8"
                     /core_sequence="CGLIRSNAKNLTRS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTGARTSGGA"
                     /leader_location="[1555:1585](+)"
                     /alternative_weights="1496.7"
                     /alternative_weights="1514.7"
     tRNA            2258..2330
                     /anticodon=(pos:816676..816678,aa:Ala,seq:tgc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03905"
                     /product="tRNA-Ala"
     gene            2258..2330
                     /locus_tag="MK744_RS03905"
                     /old_locus_tag="MK744_03905"
     rRNA            2507..5419
                     /db_xref="RFAM:RF02541"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="MK744_RS03910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="MK744_03910"
                     /product="23S ribosomal RNA"
     gene            2507..5419
                     /locus_tag="MK744_RS03910"
                     /old_locus_tag="MK744_03910"
     CDS             complement(2710..2787)
                     /gene="allorf_0817095_0817172"
                     /locus_tag="allorf_0817095_0817172"
                     /protein_id="allorf_0817095_0817172"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLVWALPVSLAATQGIEFSFSSCRY"
     CDS_motif       complement(2752..2787)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLVWALPVSLAA"
                     /locus_tag="allorf_0817095_0817172_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(2710..2751)
                     /prepeptide="core"
                     /locus_tag="allorf_0817095_0817172_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="1452.6"
                     /monoisotopic_mass="1451.7"
                     /core_sequence="TQGIEFSFSSCRY"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLVWALPVSLAA"
                     /leader_location="[2751:2787](-)"
                     /alternative_weights="1470.6"
                     /alternative_weights="1488.6"
                     /alternative_weights="1506.6"
     CDS             complement(3078..3239)
                     /gene="allorf_0817463_0817624"
                     /locus_tag="allorf_0817463_0817624"
                     /protein_id="allorf_0817463_0817624"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MGRSHGFGSTTTYSFALFRLAFAAAPSLRLNLACNRNSPVHSTKG
                     TPSLINEL"
     CDS_motif       complement(3165..3239)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGRSHGFGSTTTYSFALFRLAFAAA"
                     /locus_tag="allorf_0817463_0817624_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(3078..3164)
                     /prepeptide="core"
                     /locus_tag="allorf_0817463_0817624_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.20"
                     /molecular_weight="2924.3"
                     /monoisotopic_mass="2922.6"
                     /core_sequence="PSLRLNLACNRNSPVHSTKGTPSLINEL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGRSHGFGSTTTYSFALFRLAFAAA"
                     /leader_location="[3164:3239](-)"
                     /alternative_weights="2942.3"
                     /alternative_weights="2960.4"
                     /alternative_weights="2978.4"
                     /alternative_weights="2996.4"
                     /alternative_weights="3014.4"
     CDS             3136..3261
                     /gene="allorf_0817521_0817646"
                     /locus_tag="allorf_0817521_0817646"
                     /protein_id="allorf_0817521_0817646"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MHARLSRRDGAAAKASLNRANEYVVVDPKPCDLPMSRLKVR"
     CDS_motif       3136..3168
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MHARLSRRDGA"
                     /locus_tag="allorf_0817521_0817646_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3169..3261
                     /prepeptide="core"
                     /locus_tag="allorf_0817521_0817646_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.20"
                     /molecular_weight="3305.9"
                     /monoisotopic_mass="3303.8"
                     /core_sequence="AAKASLNRANEYVVVDPKPCDLPMSRLKVR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHARLSRRDGA"
                     /leader_location="[3135:3168](+)"
                     /alternative_weights="3323.9"
     CDS             3311..3502
                     /gene="allorf_0817696_0817887"
                     /locus_tag="allorf_0817696_0817887"
                     /protein_id="allorf_0817696_0817887"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MWVAEKFQTNLEIAGSLRNSFRASLGIENDGGRALFGLGAHLGLP
                     NSDKLRMPFIYIRESDCE"
     CDS_motif       3311..3358
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MWVAEKFQTNLEIAGS"
                     /locus_tag="allorf_0817696_0817887_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       3359..3502
                     /prepeptide="core"
                     /locus_tag="allorf_0817696_0817887_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="5135.8"
                     /monoisotopic_mass="5132.6"
                     /core_sequence="LRNSFRASLGIENDGGRALFGLGAHLGLPNSDKLRMPFIYIRE
                     SDCE"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWVAEKFQTNLEIAGS"
                     /leader_location="[3310:3358](+)"
                     /alternative_weights="5153.8"
                     /alternative_weights="5171.8"
                     /alternative_weights="5189.8"
     misc_feature    complement(3664..3680)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.16"
                     /tool="antismash"
     misc_feature    complement(3704..3719)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.31"
                     /tool="antismash"
     misc_feature    4008..4021
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.22"
                     /tool="antismash"
     misc_feature    4381..4395
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.58"
                     /tool="antismash"
     CDS             4747..4908
                     /gene="allorf_0819132_0819293"
                     /locus_tag="allorf_0819132_0819293"
                     /protein_id="allorf_0819132_0819293"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MSDGQFDWGGRLLKGNGGAQRFPQNGWKSFEECKGRRELDCETYK
                     SSRDESRA"
     CDS_motif       4747..4800
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSDGQFDWGGRLLKGNGG"
                     /locus_tag="allorf_0819132_0819293_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4801..4908
                     /prepeptide="core"
                     /locus_tag="allorf_0819132_0819293_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.00"
                     /molecular_weight="4105.4"
                     /monoisotopic_mass="4103.0"
                     /core_sequence="AQRFPQNGWKSFEECKGRRELDCETYKSSRDESRA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSDGQFDWGGRLLKGNGG"
                     /leader_location="[4746:4800](+)"
                     /alternative_weights="4123.4"
                     /alternative_weights="4141.5"
                     /alternative_weights="4159.5"
     misc_feature    complement(4768..4782)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 16.99"
                     /tool="antismash"
     CDS             5011..5241
                     /gene="allorf_0819396_0819626"
                     /locus_tag="allorf_0819396_0819626"
                     /protein_id="allorf_0819396_0819626"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MAPRCRLVASWGCSRSQGLGCSPIKAARELGSERRETVRSLSVAG
                     VGNLRGAVLSTRGPGWTYRWCTSCSAKGIAG"
     CDS_motif       5011..5166
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MAPRCRLVASWGCSRSQGLGCSPIKAARELGSERRETVRSLSVAGVGNLRGA"
                     /locus_tag="allorf_0819396_0819626_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       5167..5241
                     /prepeptide="core"
                     /locus_tag="allorf_0819396_0819626_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="2449.8"
                     /monoisotopic_mass="2448.2"
                     /core_sequence="VLSTRGPGWTYRWCTSCSAKGIAG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAPRCRLVASWGCSRSQGLGCSPIKAARELGSERRETVRSL
                     SVAGVGNLRGA"
                     /leader_location="[5010:5166](+)"
                     /alternative_weights="2467.8"
                     /alternative_weights="2485.8"
                     /alternative_weights="2503.8"
                     /alternative_weights="2521.9"
     misc_feature    5067..5081
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 17.35"
                     /tool="antismash"
     misc_feature    5075..5091
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 20.81"
                     /tool="antismash"
     rRNA            5516..5631
                     /db_xref="RFAM:RF00001"
                     /gene="rrf"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="MK744_RS03915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="MK744_03915"
                     /product="5S ribosomal RNA"
     gene            5516..5631
                     /gene="rrf"
                     /locus_tag="MK744_RS03915"
                     /old_locus_tag="MK744_03915"
     tRNA            5638..5711
                     /anticodon=(pos:820057..820059,aa:Asn,seq:gtt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03920"
                     /product="tRNA-Asn"
     gene            5638..5711
                     /locus_tag="MK744_RS03920"
                     /old_locus_tag="MK744_03920"
     misc_feature    complement(5751..5770)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 19.89"
                     /tool="antismash"
     tRNA            5755..5843
                     /anticodon=(pos:820174..820176,aa:Ser,seq:gga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03925"
                     /product="tRNA-Ser"
     gene            5755..5843
                     /locus_tag="MK744_RS03925"
                     /old_locus_tag="MK744_03925"
     tRNA            5861..5932
                     /anticodon=(pos:820279..820281,aa:Glu,seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03930"
                     /product="tRNA-Glu"
     gene            5861..5932
                     /locus_tag="MK744_RS03930"
                     /old_locus_tag="MK744_03930"
     tRNA            5960..6032
                     /anticodon=(pos:820378..820380,aa:Val,seq:tac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03935"
                     /product="tRNA-Val"
     gene            5960..6032
                     /locus_tag="MK744_RS03935"
                     /old_locus_tag="MK744_03935"
     tRNA            6043..6118
                     /anticodon=(pos:820461..820463,aa:Asp,seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03940"
                     /product="tRNA-Asp"
     gene            6043..6118
                     /locus_tag="MK744_RS03940"
                     /old_locus_tag="MK744_03940"
     tRNA            6164..6236
                     /anticodon=(pos:820582..820584,aa:Phe,seq:gaa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03945"
                     /product="tRNA-Phe"
     gene            6164..6236
                     /locus_tag="MK744_RS03945"
                     /old_locus_tag="MK744_03945"
     CDS             6167..6292
                     /gene="allorf_0820552_0820677"
                     /locus_tag="allorf_0820552_0820677"
                     /protein_id="allorf_0820552_0820677"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVAQLVEQRIEAPCVGSSTLSHAIYGGIAKWLNATDCKSVP"
     CDS_motif       6167..6247
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MVAQLVEQRIEAPCVGSSTLSHAIYGG"
                     /locus_tag="allorf_0820552_0820677_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       6248..6292
                     /prepeptide="core"
                     /locus_tag="allorf_0820552_0820677_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.90"
                     /molecular_weight="1509.8"
                     /monoisotopic_mass="1508.8"
                     /core_sequence="IAKWLNATDCKSVP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVAQLVEQRIEAPCVGSSTLSHAIYGG"
                     /leader_location="[6166:6247](+)"
                     /alternative_weights="1527.8"
     tRNA            6242..6322
                     /anticodon=(pos:820661..820663,aa:Tyr,seq:gta)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03950"
                     /product="tRNA-Tyr"
     gene            6242..6322
                     /locus_tag="MK744_RS03950"
                     /old_locus_tag="MK744_03950"
     tRNA            6327..6400
                     /anticodon=(pos:820744..820746,aa:Trp,seq:cca)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03955"
                     /product="tRNA-Trp"
     gene            6327..6400
                     /locus_tag="MK744_RS03955"
                     /old_locus_tag="MK744_03955"
     tRNA            6437..6509
                     /anticodon=(pos:820855..820857,aa:His,seq:gtg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03960"
                     /product="tRNA-His"
     gene            6437..6509
                     /locus_tag="MK744_RS03960"
                     /old_locus_tag="MK744_03960"
     tRNA            6524..6595
                     /anticodon=(pos:820941..820943,aa:Gln,seq:ttg)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03965"
                     /product="tRNA-Gln"
     gene            6524..6595
                     /locus_tag="MK744_RS03965"
                     /old_locus_tag="MK744_03965"
     tRNA            6621..6691
                     /anticodon=(pos:821038..821040,aa:Cys,seq:gca)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03970"
                     /product="tRNA-Cys"
     gene            6621..6691
                     /locus_tag="MK744_RS03970"
                     /old_locus_tag="MK744_03970"
     tRNA            6705..6788
                     /anticodon=(pos:821124..821126,aa:Leu,seq:caa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MK744_RS03975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MK744_03975"
                     /product="tRNA-Leu"
     gene            6705..6788
                     /locus_tag="MK744_RS03975"
                     /old_locus_tag="MK744_03975"
     gene            7091..>8803
                     /locus_tag="MK744_RS03980"
                     /old_locus_tag="MK744_03980"
                     /pseudo=""
     CDS             7091..>8803
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390873.1"
                     /locus_tag="MK744_RS03980"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_03980"
                     /product="SpaA isopeptide-forming pilin-related protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRRPRIKNSKLLAALVLLFQTVNTGITPLIAHAEERDYPEEVTIE
                     YDANNIYNVSGVYNNGKVFNTHTAPTYANYKGKKQPVFCIEPEVNIINPINPGYEKIPL
                     PDMPDRAKLVSILWKKVGQDPDTQAVAQKIIWQAANGYTIHTMTRPDGSTVDIPSIEAK
                     INKVVQDYQKKPSFDGTTAKLNLGKSTVLTDTNQLNLSEFNKVVKNTANIDYHVNGNQL
                     TLSTNEQSKSGILTLEKSEGTGMPVAYKKAGVQTVMAGAIDKPTTYTVKLDIETKGKLK
                     ITKIDKESGQKLPGTVFHLDFGGKFPTQEVTTGNDGTSLIEGIPHNTKVTITEKSVPVP
                     YTIDPTPVSATIKAGETIEKVSKNLREKGQIVLDKKGVETGTTLWNEHYSLAGNQFEIR
                     KKNPDGPIVQTITTDTKGHAETSKDGLKALELGTYYVTESKASTGFVNTFKPVKVVLAY
                     QNQTVPISVEYVKGTNQEITGQTTLTKEDKDTGADTQGNATFKGAQYTLFYGETNQNHA
                     KDTPVKWQDESHPEVTKGKKASEQEVTLTIDKENQVGVKHLAISNYYWKETKAP"
     misc_feature    complement(9245..9262)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.1"
                     /tool="antismash"
     gene            9560..9754
                     /locus_tag="MK744_RS03985"
                     /old_locus_tag="MK744_03985"
     CDS             9560..9754
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165752.1"
                     /locus_tag="MK744_RS03985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_03985"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_010824504.1"
                     /sec_met_domain="mature_ha (E-value: 3.5e-12, bitscore:
                     43.0, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDEENNETLINNEQVAWFEEVADQSFDDDVFGACTTNTFSLSDY
                     WGNKGNWCTATHECMGWCK"
     CDS_motif       9560..9661
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MRDEENNETLINNEQVAWFEEVADQSFDDDVFGA"
                     /locus_tag="MK744_RS03985_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9662..9754
                     /prepeptide="core"
                     /locus_tag="MK744_RS03985_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="2.00"
                     /molecular_weight="3319.7"
                     /monoisotopic_mass="3317.4"
                     /core_sequence="CTTNTFSLSDYWGNKGNWCTATHECMGWCK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRDEENNETLINNEQVAWFEEVADQSFDDDVFGA"
                     /leader_location="[9559:9661](+)"
                     /alternative_weights="3337.7"
                     /alternative_weights="3355.7"
                     /alternative_weights="3373.7"
     gene            9778..9975
                     /locus_tag="MK744_RS03990"
                     /old_locus_tag="MK744_03990"
     CDS             9778..9975
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="MK744_RS03990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_03990"
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_010824505.1"
                     /transl_table=11
                     /translation="MNNDKQNEPNVDLELGKYLEADLISLTDDEVTGGGTPTITIPISI
                     AVSGWISDKTCPTSVCTRAC"
     CDS_motif       9778..9879
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MNNDKQNEPNVDLELGKYLEADLISLTDDEVTGG"
                     /locus_tag="MK744_RS03990_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9880..9975
                     /prepeptide="core"
                     /locus_tag="MK744_RS03990_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-1.70"
                     /molecular_weight="2999.5"
                     /monoisotopic_mass="2997.6"
                     /core_sequence="GTPTITIPISIAVSGWISDKTCPTSVCTRAC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNNDKQNEPNVDLELGKYLEADLISLTDDEVTGG"
                     /leader_location="[9777:9879](+)"
                     /alternative_weights="3017.5"
                     /alternative_weights="3035.5"
                     /alternative_weights="3053.5"
                     /alternative_weights="3071.6"
                     /alternative_weights="3089.6"
                     /alternative_weights="3107.6"
                     /alternative_weights="3125.6"
     gene            10001..12922
                     /gene="lanM"
                     /locus_tag="MK744_RS03995"
                     /old_locus_tag="MK744_03995"
     CDS             10001..12922
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="MK744_RS03995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_03995"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_010825116.1"
                     /sec_met_domain="DUF4135 (E-value: 2.8e-66, bitscore:
                     221.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-47, bitscore:
                     158.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVVYSKKVYPELELKDYNEHILPIVHYIEQLNLKKLIELPTIVNY
                     KTEEKYPYYNVCMSITSEIWDKVWNNKLDAYVHNPLSFKEAICDDLSQVAFSYMIRGFS
                     EHIKLLQNVELENSYLLYNETLKRNKMKEFSETYFVTWNRCINLIISRINSIVDTVKRI
                     QQYRIDIEKKFNINRDLKIVYVKSDGDTHNDGSSVSIIYFEDKQKIIYKPRSVSGEAGY
                     TKLIMAINYKFNLNLPVLSVINCGNYGFTSFETSDETQVDMYKAGQLACLMYLLNASDM
                     HYSNILWTHKGPLPIDLETLFHPSRNRSGIPESSNSAYDSLEKSVYGTGVLPISISDKN
                     KSGSVDVGFTGIRDKNSVSPFKTFELINGFNSNIKVVWHNSATVSEDLINDSEYEKQIY
                     ENCAKVVDGFTDVYLLILKNKEFFSKEVITSFKGAKLRYIHNMTYRYEQILRVLTATEP
                     SKDLDMAHSLLSRIGILSMTSDKNITKSECSQLWKGDIPYFTINFDGTEIHSNNDIVST
                     VKNSPQSEFIRKMKKLSQKDLINQQQIIQLAFVAKLADPHAEGKLKLEELENGNQKAIE
                     KKSDGLKKTTEIIKTIKWFSQNLLNSVLDDRYEHLPKTWVGAVAKNGNNGWTPGVLGYD
                     LYSGRIGPALVLSIVGNQFSDIEATNISNDIFEKSAQILENQSFELRNVLLSGNGAFSG
                     ISGLLWAMYHAGTITNNQRWKNVAINSWELLRMDLETVDNNFFDMINGKSGAIIMRLQM
                     QDTFHPKQEFLDKCVNLAYEKINEIDSYMTSGVAHGLGHLLWFFSIINQRIKDNKIKKL
                     IIDIDTAIKKNYTNKEGVIETYLTEQNEHVSSSWCNGLSGLLIAYYEAYKADALPKVSV
                     ISVINQLKTIPISCVPVLCHGSLGVLTALEYVHESFPEETKILIHNIKNTFCSPTYIYE
                     YFKEGKGRYTLSPGLMSGKAGALLHLCKLANSDLKISPLLLGV"
     gene            12924..15083
                     /locus_tag="MK744_RS04000"
                     /old_locus_tag="MK744_04000"
     CDS             12924..15083
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165754.1"
                     /locus_tag="MK744_RS04000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04000"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_010824507.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.3e-34, bitscore:
                     116.2, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFIFKNKRKLKPTIQVAQTECGLCCVRTILEAYGCHKKLTDLR
                     QIKEPGRDGLGLTQLKELLMHMGMDVQTYKIKDLRAFEVVDFPIIAFWKGYHFVCIELF
                     SEKYVIIMDPSIGRIKISINEFQKDFSQYILVAKPNKNFVKVKKNKLDTWKKDYIWPNN
                     MMSLYLGLLMTSIILVIMTLSIPIFTQSLIDKSSYLNSISFVKTIELLLLAIITMIGLN
                     TFRSYLSIKISYKFNWHLLVGAFAHTLSLPAKFFTVRSPGEVIFRLNSLTRIQDVLGIT
                     LVQTFLDIVSSIVILGYIFWSSWTLGIIIVTLIMFMFLFLIITQKYVDSATDKELREGS
                     SVQSIQLDALASINSVKLGGYVQSYFSDWKDKLTKLLSASSHRMYLQQGIVGSVLYGMQ
                     TIFPLIILVISLYQEKLGTLSLGQVIAIQSTVSMLFNYSNTIFSTLSNIMVVERYIELS
                     EDIFDYPIESSVRSDHIMESGNLSINNLYFQYTSDTKPALKNINLKILDGETVAFVGVS
                     GSGKTTLAKICSSLFEPTKGDIFFSDINFQRYNLDQLRKSISYIPQEAHLHNRTIIENL
                     KLGSQLSEEKIIELCSSLEFLSFISDLPMGYNTVISEMGANLSGGQRQRIHIARAILQN
                     PKILIMDEATSSLDNISQSSVYTELSKLECTKIVIAHRLETILNADKIFVLRDGEIVQT
                     GHHNDLVQQPGDYKDLFNTVIEKEK"
     misc_feature    complement(12934..12947)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     misc_feature    12936..12949
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.06"
                     /tool="antismash"
     gene            15086..17848
                     /gene="lanM"
                     /locus_tag="MK744_RS04005"
                     /old_locus_tag="MK744_04005"
     CDS             15086..17848
                     /GO_process="GO:0009403 - toxin biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lanM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="MK744_RS04005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04005"
                     /product="type 2 lanthipeptide synthetase LanM"
                     /protein_id="WP_010825118.1"
                     /sec_met_domain="DUF4135 (E-value: 3.6e-72, bitscore:
                     240.9, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.2e-25, bitscore:
                     85.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNDNKLVNIIEDIFKDIVEHTHTTLKRSFTTFQEKETEVFIKCF
                     HALIEYHINRVVQKTFIYEFHEFRKSLNMPANPNSSVAFDLFLQKLDKQMVEKWLNKYS
                     YLRTIIHTIINNTSLYIIAVCKNFKEDIDQLNNNEMISKNSYLTAINALDSDPHNGSKI
                     VLCFEFSNEEKILYKPRSLEIDQLIDTIFSDILKFKGLKYNTPIAQTICRNSYGWQKFI
                     SHTFIDEADLSEAYYNLGLCAAVFRSIGATDLHDENVIFNGTTPYFIDLETSLKPSHEE
                     INEDSIWDVLNKELSNSIANTCIIPAKLMVAPHNILIGAINTPYPQKTEELCFTLTNPG
                     TDAVDISKQNIIVSRDSAPIMLEKNKFPSPLPYQQDFVNGYEEGIKSVIVNREKISDLL
                     SSFPCTSRIIVRPTVQYFFLLDACLYPENLIDESAIDKILSYMKPSKMFTESENASKVL
                     EAEKKALKKGDIPYFSIGSNKHTINLMNINTNTFEMSPIENALYSLNNLSDRALLIDKR
                     LIAEGFSEIRIHEATFENNKTKKSQAKMFTDVLKEVTIDNPDALFKLIINQSITTKSKN
                     AETGWLNGVYGDMNIAYNSISCISLHDAGGILFLLKHLTEYKKCVDDIETNELYIRASK
                     GVNSLKNTIYGSTEVSNTPMSIISGSNSLEFLFNHEQKKLKYLDKTISKIQLENIESGD
                     VFLGPIGIALVNATFPNTSIDNIIYFTEKFHNTKLPSEGIAHGNLGVLWTNFRLNYALD
                     RLDICKNIFHETTRIKFEESVENVGWCNGNSGLLMVLTEMATLLKVDINLFDLAKKSTI
                     LPLETPLDLSICHGVSGVLQSLLFSFKVSKKSEYIMLANEYWLSVLKLIDINGYYTGEK
                     NRDYLLGYFLGWSGMADSALLLKMYNEGSSPLIPLNLSSLDYQKKLMEV"
     gene            17852..18937
                     /locus_tag="MK744_RS04010"
                     /old_locus_tag="MK744_04010"
     CDS             17852..18937
                     /NRPS_PKS="Domain: PKS_ER (48-175). E-value: 8.3e-13.
                     Score: 40.1. Matches aSDomain:
                     nrpspksdomains_MK744_RS04010_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019845.4"
                     /locus_tag="MK744_RS04010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04010"
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_010825119.1"
                     /sec_met_domain="ADH_N (E-value: 8.5e-06, bitscore: 22.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVAINPRYKNSLEFKKMETVKFGSTNVLFGLVELNQPDFDIN
                     NLQNDDYILIKVKYFSCNYRDKSILLEAYTSEKNENRLFFPFGSEFSAEIIKIGKNVNN
                     FNVGDFVMPNCEYPHGVKPGIPSNFASLGWLKIHKSKVIKIPARLSLEEAACFSLGSQT
                     ASSMIRRSNILKESGNPVVFSARSATSMFIIRQLLIQGITPICISTTSWTDFEKEYIYP
                     CEVERLEDVSLQAMKRNITHVFDPFFDLNVENAVNLLQIGGTYITCGLLNQHPLLSEKI
                     PIENEPILRRALSMGVMKNITFIGNCLGTYEDLQNAISLEERFSVKPVIDKSYNVNQYL
                     DFIDRSFFNANKIGKVSLTYH"
     aSDomain        17996..18376
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MK744_RS04010_PKS_ER.1"
                     /evalue="8.30E-13"
                     /label="MK744_RS04010_PKS_ER.1"
                     /locus_tag="MK744_RS04010"
                     /protein_end="175"
                     /protein_start="48"
                     /score="40.1"
                     /tool="antismash"
                     /translation="NDDYILIKVKYFSCNYRDKSILLEAYTSEKNENRLFFPFGSEFSA
                     EIIKIGKNVNNFNVGDFVMPNCEYPHGVKPGIPSNFASLGWLKIHKSKVIKIPARLSLE
                     EAACFSLGSQTASSMIRRSNILK"
     misc_feature    complement(19029..19044)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 24.94"
                     /tool="antismash"
     gene            19412..19654
                     /locus_tag="MK744_RS04015"
                     /old_locus_tag="MK744_04015"
     CDS             19412..19654
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814620.1"
                     /locus_tag="MK744_RS04015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04015"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_010824510.1"
                     /transl_table=11
                     /translation="MKKKIHEESIRNKVYEYRVLARLSQQELADRVGVSKQTIFVMEKG
                     NYVPSLLLAFRISNFFNVPLTEIFEYDLGGQNNDE"
     gene            19644..19982
                     /locus_tag="MK744_RS04020"
                     /old_locus_tag="MK744_04020"
     CDS             19644..19982
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814618.1"
                     /locus_tag="MK744_RS04020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04020"
                     /product="hypothetical protein"
                     /protein_id="WP_010824511.1"
                     /transl_table=11
                     /translation="MMNKSIGFSFNALNEWSEKSIGNYNLLIGVGFLLVMISSITLVYL
                     LLKLGQRDERTTKIHLNVCCYMLVTIVLCDLFFPKEYMQNILFLFKYALAFSISLIYLL
                     KKYKQDLC"
     gene            20037..20900
                     /locus_tag="MK744_RS04025"
                     /old_locus_tag="MK744_04025"
     CDS             20037..20900
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="MK744_RS04025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04025"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_010824512.1"
                     /transl_table=11
                     /translation="MNINKVSKSYNNTSVLDNISFNFKKGEIIGLVGRNGAGKSTLMKI
                     ITENILNFNGSIMRNSSIGYLIEEPKLIASMSGLEHLIYFSRIYGNKFDINEFKDLLVS
                     LNLYQILNKKVREYSLGMKQKLAVVISILNYPDYVVLDEPTNGMDVESSYEMLNALKKL
                     AIKTDLGILISSHKLEDIEIICDRILFLENGVLIGEETINQSSQNIIKIIFSNNDDLTM
                     FINKQELGNIYNVTQDTLTLQTSLNSSDVFTLLEELNIFIIDCHTEKNTLRNIYLDKFG
                     GEKNEV"
     gene            21061..21615
                     /locus_tag="MK744_RS04030"
                     /old_locus_tag="MK744_04030"
     CDS             21061..21615
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MK744_RS04030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MK744_04030"
                     /product="ABC transporter permease"
                     /protein_id="WP_241408306.1"
                     /transl_table=11
                     /translation="MLGITAMVLQSTYLINNDFSYKTISLIYNSKENRLGYIIGNILIS
                     IFVGAIFSAIGIILFIISKYLGVPGKLEIIFLLGFILDVILVIVIYFLCGYCLFLSGFR
                     SGAVYGILILFLLFIPNLLSNIVYGYSNPFLSAVVENFPGYYLPITVGSNVFTLLQYII
                     SLITIFVLFTVVLKKSLRVEV"
     misc_feature    complement(21854..21869)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.49"
                     /tool="antismash"
     misc_feature    22729..22747
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.25"
                     /tool="antismash"
     gene            22855..23226
                     /locus_tag="MK744_RS04035"
                     /old_locus_tag="MK744_04035"
     CDS             22855..23226
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408082.1"
                     /locus_tag="MK744_RS04035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04035"
                     /product="DUF771 domain-containing protein"
                     /protein_id="WP_002408082.1"
                     /transl_table=11
                     /translation="MKEVKKLEQVIEYSAQILLPKNFILIQREEYDHLIRAGFKGNCIS
                     VEAFRKKHTCLSRPMFNERILLNPRFKKILDIRENPNGCVSYPKGGSAGKYYILESKML
                     MFIEEYFSEIFTSFQIDAV"
     gene            23277..23609
                     /locus_tag="MK744_RS04040"
                     /old_locus_tag="MK744_04040"
     CDS             23277..23609
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MK744_RS04040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MK744_04040"
                     /product="hypothetical protein"
                     /protein_id="WP_010825122.1"
                     /transl_table=11
                     /translation="MGISKRGTKWRAFVSVKKEGGKYRNKTLGSFDTKFEAVKAVEHAQ
                     SVASKDRRMAFTLPFYEYFEWFFQKYKKEACSKKTQGHYQHTKRYIKRYLGDTPLSDLT
                     NDKYVE"
     gene            23667..24425
                     /locus_tag="MK744_RS04045"
                     /old_locus_tag="MK744_04045"
     CDS             23667..24425
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012798.4"
                     /locus_tag="MK744_RS04045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04045"
                     /product="site-specific integrase"
                     /protein_id="WP_010825123.1"
                     /transl_table=11
                     /translation="MRACVKQAFALGHIPIEFTSGSSLRGLGDKSKEKPIYQKYIDDTQ
                     YKKVLQYVVQHRDKESSIYYVIIFSLLTGCRFSEIVGITIDDLNFEQGFVDINKTYDHM
                     NPPSNSSDWLPCKNKNSYRKVEMPQNLAELLQEFWQYQQKKCQFHQIKNPRKQIFFDWQ
                     EGACDNRKANIEIKKILVTCGITDKPKFSMHCCRHTFVSFLIYQGYSVEEVALIVGDKP
                     EEIRKTYYHVFQEYEVRTRSKTRKLMNSLF"
     misc_feature    complement(23681..23694)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.56"
                     /tool="antismash"
     gene            complement(24616..24849)
                     /locus_tag="MK744_RS04050"
                     /old_locus_tag="MK744_04050"
     CDS             complement(24616..24849)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777507.1"
                     /locus_tag="MK744_RS04050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04050"
                     /product="hypothetical protein"
                     /protein_id="WP_010777507.1"
                     /transl_table=11
                     /translation="MTTMLAIIGTVAIITVQVIEYNMTEIHIPTAGTFNDDDAEPPHSS
                     VTLVFIRTILITLSLNFPSHFFEMVFFMYSRK"
     regulatory      complement(24914..25081)
                     /bound_moiety="magnesium"
                     /db_xref="RFAM:RF00380"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00380"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="The M-box (ykoK) riboswitch appears to function as a
                     genetic 'off' switch that is important for maintaining
                     magnesium homeostasis in bacteria; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(25144..25923)
                     /locus_tag="MK744_RS04055"
                     /old_locus_tag="MK744_04055"
     CDS             complement(25144..25923)
                     /EC_number="7.6.2.7"
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360638.1"
                     /locus_tag="MK744_RS04055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04055"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_002360638.1"
                     /transl_table=11
                     /translation="MENKELLSIKSVYKEFEIEGHSEHLKVLENIDLTVKTNEFLSIIG
                     QSGTGKSTLLRSIAGLLRTTRGEITFEDKIINEPDANIGMVFQHFALFPWLTVEKNISF
                     GLENRKEISREQINKRVSNLIEMIGLTGFEKAYPRELSGGMKQRVGFARALAIEPSLLL
                     LDEPFSALDIITASQLSNDLLEIWLNNQIATKSIVMITHDVQQAVQLSDRVVLMDANPG
                     RIAKIYSIDIPRNQRSPKTTIDIVEQITEEMVRRIHL"
     gene            complement(26012..27784)
                     /locus_tag="MK744_RS04060"
                     /old_locus_tag="MK744_04060"
     CDS             complement(26012..27784)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016630917.1"
                     /locus_tag="MK744_RS04060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MK744_04060"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_025190697.1"
                     /transl_table=11
                     /translation="MEVFKLKAVTASSKKNTLLAKSIGNLTLLIILGIFIFIIVFSWLK
                     MNRPLHTLPSEEFLATPSKTDDFLSPSNLFYFSIRTMFRMIVGMAWSFLFSFIFGILAV
                     KYKTARRVILPLVNFLESVPLLGFLTFTTAWLLGLFPGNVMGAEAVAIFAIFTGQAWNI
                     MLTLYQIMEVIPSDLVNVTDQFKYNAWEKFWRLEFVYSIPGLLWNVIISQTAAWFALVA
                     SEQASVAFPKETNLYLPGIGSYIQVALNRADFKSCLWAVFALLINVVILNFLVFQPLVR
                     ATYYFKYETDVESTTPPKSIIYHLLKKATLTKYFSKAFVKFSHFWIYDLPKVWYFFKLD
                     YLYRLLAKLRHFFKTLWYVSLTIIGVYCSIKLYHFLPHQDFSMIPRLTLYTTLRVTLAM
                     VVAGIIFTPLAIWVANDNRRLSIVQPIGQILGSIPSNVYTPFIVLIISMGFNKLEWWIL
                     PLIMVGCQWYFFFNVIAGYLAIPDDIRDVTKLFKLSKWQWWTKFLIPSILPYLITAIIN
                     AAGAAWNADIAAESIQWGKKSIDVTGLGQYIAANDGVKDKSALGTLAMCFVVGLCIAFV
                     WQPLYRAAKQKFHY"
ORIGIN
        1 taacgaacat ttcagtaaga gaaaagggat tataagataa agaaacgaat gttttctttg
       61 cagaaaatat tcatcgttcg aaattgaaaa aaatgttatt tttctgcaaa ataatagttg
      121 cgttttagaa aaatccttgg tatattaata tctgttctga caaacagttc gttaagaaaa
      181 aagttttaaa aagttaaaaa tttttcttga cgaaaagata aataacatgt tagaataaca
      241 aagtcgttaa agagattgct tttaaatcaa tcatttgatc aaaaaaactt gttataaaat
      301 aacaaaaaag ttttaaaaag ttgttgacaa acaactgaga taatgataag atatagaagt
      361 tgtcacaaca gacgacaaca accgagcaaa acaacttaaa aaaacttttt taaaaagttc
      421 ttgacattca aacgaaagtt tgttatgata taaaagttgc tgcgaggtaa cgtagacctt
      481 tgaaaactga acaaagaata gacgaaccaa atgtgtaggg cgtcttgatt caattcaaga
      541 caacaaacat ttttaacgag caagcaatat gctagcaaac aaattgagct taacaatcgc
      601 aagattgttc taacttttat tatgagagtt tgatcctggc tcaggacgaa cgctggcggc
      661 gtgcctaata catgcaagtc gaacgcttct ttcctcccga gtgcttgcac tcaattggaa
      721 agaggagtgg cggacgggtg agtaacacgt gggtaaccta cccatcagag ggggataaca
      781 cttggaaaca ggtgctaata ccgcataaca gtttatgccg catggcataa gagtgaaagg
      841 cgctttcggg tgtcgctgat ggatggaccc gcggtgcatt agctagttgg tgaggtaacg
      901 gctcaccaag gccacgatgc atagccgacc tgagagggtg atcggccaca ctgggactga
      961 gacacggccc agactcctac gggaggcagc agtagggaat cttcggcaat ggacgaaagt
     1021 ctgaccgagc aacgccgcgt gagtgaagaa ggttttcgga tcgtaaaact ctgttgttag
     1081 agaagaacaa ggacgttagt aactgaacgt cccctgacgg tatctaacca gaaagccacg
     1141 gctaactacg tgccagcagc cgcggtaata cgtaggtggc aagcgttgtc cggatttatt
     1201 gggcgtaaag cgagcgcagg cggtttctta agtctgatgt gaaagccccc ggctcaaccg
     1261 gggagggtca ttggaaactg ggagacttga gtgcagaaga ggagagtgga attccatgtg
     1321 tagcggtgaa atgcgtagat atatggagga acaccagtgg cgaaggcggc tctctggtct
     1381 gtaactgacg ctgaggctcg aaagcgtggg gagcaaacag gattagatac cctggtagtc
     1441 cacgccgtaa acgatgagtg ctaagtgttg gagggtttcc gcccttcagt gctgcagcaa
     1501 acgcattaag cactccgcct ggggagtacg accgcaaggt tgaaactcaa aggaattgac
     1561 gggggcccgc acaagcggtg gagcatgtgg tttaattcga agcaacgcga agaaccttac
     1621 caggtcttga catcctttga ccactctaga gatagagctt tcccttcggg gacaaagtga
     1681 caggtggtgc atggttgtcg tcagctcgtg tcgtgagatg ttgggttaag tcccgcaacg
     1741 agcgcaaccc ttattgttag ttgccatcat ttagttgggc actctagcga gactgccggt
     1801 gacaaaccgg aggaaggtgg ggatgacgtc aaatcatcat gccccttatg acctgggcta
     1861 cacacgtgct acaatgggaa gtacaacgag tcgctagacc gcgaggtcat gcaaatctct
     1921 taaagcttct ctcagttcgg attgcaggct gcaactcgcc tgcatgaagc cggaatcgct
     1981 agtaatcgcg gatcagcacg ccgcggtgaa tacgttcccg ggccttgtac acaccgcccg
     2041 tcacaccacg agagtttgta acacccgaag tcggtgaggt aacctttttg gagccagccg
     2101 cctaaggtgg gatagatgat tggggtgaag tcgtaacaag gtagccgtat cggaaggtgc
     2161 ggctggatca cctcctttct aaggaatatt acggaaatac acatttcgtc tttactttgt
     2221 tcagttttga gaggtctact ctcaatcaaa taagttcggg gccttagctc agctgggaga
     2281 gcgcctgctt tgcacgcagg aggtcagcgg ttcgatcccg ctaggctcca ttgatagctt
     2341 ttgctatcag attcgttcat tgaaaactgg atattgaagt aaaaagaatc aaaacaaacc
     2401 gagaacaccg cgttgaatga gttttttaat aagttcaatt gcttatttat tgattaacct
     2461 tctatcgcta gaagaagtga tcaagaccca accgtaaggt tgataaggtt aagtgaataa
     2521 gggcgcacgg tggatgcctt ggcactagga gccgatgaag gacgggacta acaccgatat
     2581 gctttgggga gctgtaagta agctatgatc cagagatttc cgaatggggg aacccaatat
     2641 cttttatagg atattacttt tcagtgaata catagctgat tagaggtaga cgcagagaac
     2701 tgaaacatct tagtacctgc aggaagagaa agaaaattcg attccctgag tagcggcgag
     2761 cgaaacggga agagcccaaa ccaacaagct tgcttgttgg ggttgtagga ctccaatatg
     2821 gtagtctgtt agtatagttg aaggatttgg aaaattccgc taaagagggt gaaagccccg
     2881 tagacgaaat gctgacaaca cctaggagga tcctgagtac ggcggaacac gagaaattcc
     2941 gtcggaatcc gcggggacca tcccgcaagg ctaaatactc cctagtgacc gatagtgaac
     3001 cagtaccgtg agggaaaggt gaaaagcacc ccggaagggg agtgaaatag atcctgaaac
     3061 cgtgtgccta caacaagtca aagctcgtta atgagtgatg gcgtgccttt tgtagaatga
     3121 accggcgagt tacgattgca tgcgaggtta agtcgaagag acggagccgc agcgaaagcg
     3181 agtctgaata gggcgaatga gtatgtagtc gtagacccga aaccatgtga tctacccatg
     3241 tccaggttga aggtgcggta aaacgcactg gaggaccgaa cccacgtacg ttgaaaagtg
     3301 cggggatgag gtgtgggtag cggagaaatt ccaaacgaac ttggagatag ctggttctct
     3361 ccgaaatagc tttagggcta gcctcggaat tgagaatgat ggaggtagag cactgtttgg
     3421 actaggggcc catctcgggt taccgaattc agataaactc cgaatgccat tcatttatat
     3481 ccgggagtca gactgcgagt gataagatcc gtagtcgaaa gggaaacagc ccagaccacc
     3541 agctaaggtc ccaaaatata tgttaagtgg aaaaggatgt ggggttgcac agacaactag
     3601 gatgttggct tagaagcagc caccatttaa agagtgcgta atagctcact agtcgagtga
     3661 ccctgcgccg aaaatgtacc ggggctaaac atattaccga agctgtggac tacaccatta
     3721 ggtgtagtgg taggagagcg ttctaagggc gttgaaggtc gatcgtgagg acggctggag
     3781 cgcttagaag tgagaatgcc ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg
     3841 tatgactaag gtttcctggg gaaggctcgt ccgcccaggg ttagtcggga cctaagccga
     3901 ggccgatagg cgtaggcgat ggacaacagg ttgatattcc tgtaccagtt gtttttgttt
     3961 gagcaatgga gggacgcagt aggctaagga atgcatgcga ttggaagtgc atgtccaagc
     4021 aatgagtctt gagtagagtt aaatgcttta ctctttaagg acaagttgtg acggggagcg
     4081 aaataatagt agcgaagttc ctgatgtcac actgccaaga aaagcttcta gtgagaaaac
     4141 aactgcccgt accgtaaacc gacacaggta gtcgaggaga gtatcctaag gtgagcgagc
     4201 gaactctcgt taaggaactc ggcaaaatga ccccgtaact tcgggagaag gggtgctgac
     4261 gaccgtcagc cgcagtgaat aggcccaagc gactgtttat caaaaacaca ggtctctgca
     4321 aaatcgtaag atgaagtata ggggctgacg cctgcccggt gctggaaggt taagaggatg
     4381 ggttagcttc ggcgaagctc agaattgaag ccccagtaaa cggcggccgt aactataacg
     4441 gtcctaaggt agcgaaattc cttgtcgggt aagttccgac ccgcacgaaa ggcgtaacga
     4501 tttgggcact gtctcaacga gagactcggt gaaattttag tacctgtgaa gatgcaggtt
     4561 acccgcgaca ggacggaaag accccatgga gctttactgt agtttgatat tgagtgtttg
     4621 taccacatgt acaggatagg taggagccga tgagaccgga acgctagttt cggaggaggc
     4681 gctggtggga tactaccctt gtgttatgaa ccctctaacc cgcaccacta atcgtggtgg
     4741 gagacagtgt cagatgggca gtttgactgg ggcggtcgcc tcctaaaagg taacggaggc
     4801 gcccaaaggt tccctcagaa tggttggaaa tcattcgaag agtgtaaagg cagaagggag
     4861 cttgactgcg agacctacaa gtcgagcagg gacgaaagtc gggcttagtg atccggtggt
     4921 tccgcatgga agggccatcg ctcaacggat aaaagctacc ctggggataa caggcttatc
     4981 tcccccaaga gtccacatcg acggggaggt ttggcacctc gatgtcggct cgtcgcatcc
     5041 tggggctgta gtcggtccca agggttgggc tgttcgccca ttaaagcggc acgcgagctg
     5101 ggttcagaac gtcgtgagac agttcggtcc ctatccgtcg cgggcgttgg aaatttgaga
     5161 ggagctgtcc ttagtacgag aggaccggga tggacttacc gctggtgtac cagttgttct
     5221 gccaagggca ttgctgggta gctatgtagg gaagggataa acgctgaaag catctaagtg
     5281 tgaagcccac ctcaagatga gatttcccat ttctttaaga aagtaagacc cctgagagat
     5341 gatcaggtag ataggttgga agtggaaggc tagtgatagt tggagcggac caatactaat
     5401 cggtcgagga cttaaccaaa gaatggataa gtaaaagcaa cttggttatt ttgattcaaa
     5461 cttcaatcca gttttgagtg aatgaagatt caactcaata agaaacaaca cccagtgtgg
     5521 tggcgatagc gagaaggata cacctgttcc catgccgaac acagaagtta agcttcttag
     5581 cgccgattgt agtgaagggt ttccctttgt gagagtagga cgtcgccacg cgattattcc
     5641 ggcatagctc agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc
     5701 tactgccgga gtttaacata tgaaatatca tgagtatgtg cttctttcag ctatggagag
     5761 ttgtccgaga ggccgaagga gcatgattgg aaatcatgta ggcggtaaac actgtctcaa
     5821 gggttcgaat cccttactct ccgtttcata tttacaaact ggcccgttgg tcaagcggtt
     5881 aagacaccgc cctttcacgg cggtaacacg ggttcgagtc ccgtacgggt catttatttt
     5941 aatagtaaca ttcctttttg gaggtttagc tcagctggga gagcacctgc cttacaagca
     6001 gggggtcagc ggttcgatcc cgttaacctc cattactcgg ttggttccgt ggtgtagggg
     6061 ttaacatgcc tgcctgtcac gcaggagatc gcgggttcaa atcccgtcgg aaccgccatt
     6121 taatgttgtt acttgaaaat tatttgaaca agcttttgtt ttaggcgtgg tagctcagtt
     6181 ggtagagcaa cggattgaag ctccgtgtgt cggcagttcg actctgtctc acgccattta
     6241 tggaggaata gcgaagtggc taaacgcgac ggactgtaaa tccgttcctt agggttcagt
     6301 ggttcgaatc cactttcctc cattttaggg gcatagttta aaggtagaac aacggtctcc
     6361 aaaaccgttg gtgtgggttc aattcctgct gcccctgcca tttaattatt taatagatac
     6421 actttttaag attacggcga tcgtggtgaa gtggttaaca caccagattg tggctctggc
     6481 attcgtgggt tcgattccca tcggtcgccc tttgtaattt tattggggta tagccaagcg
     6541 gtaaggcaac ggactttgac tccgtcatgc gttggttcga atccagctac cccagttttt
     6601 ttgtaacaaa aatggaatat ggcggtatag ccaagtggta aggcagaggt ctgcaaaacc
     6661 ttcatcaccg gttcaaatcc ggttaccgcc ttccaaaata tcttgccggc gtggcggaat
     6721 tggcagacgc gctggactca aaatccagtt ccttcacggg agtgccggtt cgaccccggc
     6781 cgccggtata ctaaagactg ttaaatcaat gatttaacag tctttttttc gttatagtgg
     6841 tgcgaaaatg gtgcgaatga aattttttat agtttttctt gtaaaaaaag tagttattta
     6901 attagataaa gggctttaaa tagttattga atatggtcac tattatttta ctagaaaata
     6961 taaaataact tagttaaaag taatatacaa atgaagattt aaatgtatca atatataatc
     7021 aaataagaaa ttaagacgtt caaaatttga gcgtcttttt ttatattcaa aatcagagag
     7081 gagtataaaa gtgagaagac caagaataaa gaatagtaaa ttgctagcgg ctttagtatt
     7141 gctattccaa actgtaaata cgggtataac accacttatc gctcatgcag aagaaagaga
     7201 ttatcctgaa gaagtaacaa ttgagtatga tgctaataat atttacaatg tttcgggggt
     7261 atataataat ggaaaagttt ttaatacgca tacagcccct acctatgcta attataaagg
     7321 gaagaagcaa cctgttttct gcattgagcc agaagtgaat attattaatc caatcaatcc
     7381 aggttatgaa aaaattcctt tacctgatat gccagaccgc gcaaaattag tttccatttt
     7441 atggaaaaag gtgggtcaag atcctgatac tcaagccgtt gcacaaaaaa ttatttggca
     7501 agcagccaat ggctatacca tccataccat gactcgacca gatggcagta cagtagatat
     7561 tccaagcatt gaagcaaaaa tcaataaagt tgttcaagac tatcaaaaga aacctagctt
     7621 tgatggaacg acagctaaac tgaacttagg aaagtcgaca gttttaacag atacgaatca
     7681 attaaacttg tcagaattta ataaagtggt caaaaatact gcgaacattg actatcatgt
     7741 gaacggtaac caattaactt tgagtacgaa tgaacagtca aaatcgggta tactcacact
     7801 agaaaagtca gaaggaacag gcatgccagt tgcttataaa aaagctggtg tacaaaccgt
     7861 gatggcaggt gccattgata aaccaacgac ttatacagtc aaactggaca tagaaacaaa
     7921 aggtaaatta aaaattacaa aaatagataa agagtcaggt caaaaattac caggaacagt
     7981 ctttcattta gattttggcg gaaagtttcc cacacaagaa gtgacaacag gaaatgatgg
     8041 aactagccta attgaaggga ttcctcataa cacaaaagtg actattactg agaaatctgt
     8101 tccagtgccg tatacgattg acccaacgcc ggtttctgcc accataaaag caggtgaaac
     8161 gattgaaaaa gtatctaaaa atcttcgaga aaaaggacag atcgttttag ataaaaaagg
     8221 tgttgaaaca ggaaccaccc tttggaatga acattactca ttagcgggta atcaatttga
     8281 gatacgtaaa aagaacccag atggaccgat tgttcaaacg ataactacgg atacaaaagg
     8341 acatgcagaa acgtcaaaag atggtttaaa agcgttagaa ttgggaacgt attatgtgac
     8401 tgaaagcaaa gctagtacag ggtttgtaaa tacgtttaaa ccagtcaaag tggtcttagc
     8461 ttatcaaaat caaaccgtgc ctatttcagt agaatatgta aaaggaacca accaagaaat
     8521 tacaggacaa actactttaa ccaaagaaga caaagataca ggagcggata cgcaaggaaa
     8581 tgctacgttt aaaggggcac aatatacttt gttctatgga gaaaccaatc aaaatcatgc
     8641 taaagataca cctgtaaaat ggcaagatga aagtcatcca gaagttacaa aaggtaagaa
     8701 agcttctgaa caagaagtaa cgttaaccat tgataaagaa aatcaagtgg gggtgaaaca
     8761 cttagccatt tccaactact attggaaaga aaccaaggca ccttctttgt aattataaaa
     8821 taattttatt gttagactag aattcgtaag cgtaaagcct aaaattaaaa gaaacctgct
     8881 aataaaagtc aatgaaaaaa gtattagctt attgggagct acatcattag cttcaacaac
     8941 attactagga ggaagtgtat ttgtagtaag tgatacagta aatcctgctc cagcaacagc
     9001 agctacatct gttaaagaag atagatctga cgattaatca aattccatca aatcctaaga
     9061 gatgaaaagc taaaatattg ttgtaacgta gaaaactatg tataactcag ttttctgttt
     9121 taaaataaaa taagaataaa agaaaacaca attctaagag gattgtgttc ttttagggtg
     9181 gaataaatgt taaataggga attctggcaa taaattagct tggatattgc taaaattata
     9241 attactaaca tacaaataac attacgaaat atcaaggtga acagagttta agcataaaaa
     9301 gatagtcata ctttttattt tgattattct gtaaatggca aatgatcttt attgacacaa
     9361 caggtatttt ttatttcttg acgatagata cgaatcagct tctttataaa ttttagtaaa
     9421 ttgatttacc agtttggagc tgattgtttc tataaaataa agttacaaaa ggaaaagtta
     9481 cgtgtctgaa acgtctatta acattgaatt ttatacgttt tcatgtgacg aataatgaca
     9541 ttctaaggag gtgaactata tgcgtgatga agaaaacaac gaaactttga tcaataatga
     9601 acaagttgct tggttcgaag aagtagccga tcaatcattc gacgatgacg ttttcggtgc
     9661 ctgcactact aatacatttt cattaagtga ttattgggga aacaaaggaa attggtgtac
     9721 agctacacac gaatgtatgg gttggtgtaa ataattttat aaaaaggagc ttttataatg
     9781 aataatgaca aacaaaatga accaaatgtg gatttagagt tgggtaaata cctagaggca
     9841 gatttaattt ctttaacaga cgatgaagtt acaggaggag gaacacccac aattactatt
     9901 cctatttcta tcgctgtttc aggttggatt tcagataaaa catgtccaac aagcgtttgt
     9961 acgagggctt gttaataaaa tgaatgtgag gtgtgaatga atggttgtct acagcaaaaa
    10021 agtttatccc gaattagagt taaaagatta taatgagcat attttaccca tagttcatta
    10081 tattgaacaa ttaaatttaa aaaaattaat tgaactgcca actatagtaa attataaaac
    10141 agaggaaaaa tatccatact ataatgtatg tatgtccatt actagcgaaa tttgggataa
    10201 agtttggaat aacaaattag acgcctatgt tcacaatcca ttatctttca aagaagctat
    10261 ttgcgatgat ttatcgcaag tagctttctc ttatatgata cgaggatttt ctgaacatat
    10321 aaaattatta caaaatgtcg aattagaaaa ttcgtattta ctttataatg aaacactaaa
    10381 aagaaataag atgaaagaat tttctgagac gtattttgtt acttggaata gatgtattaa
    10441 cttaataata agtagaataa actctattgt agatactgtc aaaagaatac agcaatacag
    10501 aatagatatt gagaaaaaat ttaatattaa tagagactta aaaatagtgt atgtgaagtc
    10561 tgatggtgat acgcataatg acggatcatc agtgtcaatt atttattttg aagacaaaca
    10621 aaaaattatc tataaaccac gttctgtttc tggagaagcc ggatacacca aattaattat
    10681 ggctatcaat tataaattta atttgaatct acctgtgtta tctgtgatta attgtggaaa
    10741 ttacggtttt acctcatttg aaactagtga cgaaactcag gttgatatgt ataaagctgg
    10801 ccaactcgca tgcttaatgt acttattgaa tgcgtccgat atgcattata gtaatatatt
    10861 atggacacat aaaggaccgt tgccaataga tctcgaaacg ttattccacc cgtctcgcaa
    10921 tagatccggt ataccagaat ctagcaatag tgcctatgac tctttagaaa agtctgttta
    10981 tggtactgga gtactaccaa tttctattag cgataaaaac aaaagtggtt cagttgacgt
    11041 tggtttcacg ggaattagag ataaaaacag tgttagtcct tttaaaacct ttgaattaat
    11101 caacggattt aattctaaca ttaaagttgt atggcataac tcagccactg tttctgaaga
    11161 tcttataaat gactcggaat atgaaaaaca gatttatgaa aactgtgcta aagttgtcga
    11221 tggttttact gatgtctact tattaatact aaaaaacaaa gaatttttta gtaaagaagt
    11281 aataacatct tttaaaggtg ctaaacttcg ttatatccac aatatgactt atagatatga
    11341 gcaaatatta cgagttttaa cagcaacaga accttcgaaa gatttagata tggcacattc
    11401 actattatct agaattggta ttttaagtat gactagtgat aaaaatatta ctaaatccga
    11461 atgtagtcaa ttgtggaagg gagatattcc ttactttaca ataaattttg atggtacaga
    11521 aattcatagt aataatgata ttgtatccac agttaaaaat agcccccaat ccgaatttat
    11581 tcgtaagatg aaaaaactat cacaaaaaga tttaattaat cagcaacaaa ttatacaact
    11641 agcatttgtt gctaaattag cagacccaca cgcggaagga aaattaaaac tagaagagtt
    11701 agagaatggg aatcaaaaag ctatagagaa aaaaagtgat ggactaaaaa agactacaga
    11761 gataattaaa actattaaat ggttttctca aaatttatta aattcagtac ttgatgatcg
    11821 atatgaacat ttgccaaaaa cttgggtagg tgcagtagct aaaaacggga ataatggatg
    11881 gacacctgga gttttaggat acgatttata tagtggcaga ataggtcctg cactagtgct
    11941 atctattgta ggtaatcagt tttctgatat tgaggctaca aatatttcca acgatatatt
    12001 tgaaaaatct gctcaaatcc tcgaaaatca aagttttgaa ttaaggaatg tgttgttgtc
    12061 aggtaatgga gctttttcag gtatctctgg gttactttgg gcaatgtatc atgcaggtac
    12121 cattacaaat aaccaacgat ggaaaaacgt cgctattaat tcttgggaac ttttaagaat
    12181 ggacttagaa actgttgaca ataatttttt tgatatgatt aatggaaaaa gtggtgcgat
    12241 tataatgcgc ttacagatgc aagacacttt ccatccaaaa caagaatttt tagataagtg
    12301 tgttaattta gcttatgaaa aaattaacga aattgatagt tatatgactt ctggagttgc
    12361 acacggatta ggacatttac tttggttttt ttctataatt aatcaaagaa taaaagataa
    12421 taaaataaaa aaattaatta tagatataga tactgctatc aagaagaatt acacaaataa
    12481 agaaggtgtc atcgaaactt acttaactga acagaatgag catgtgtcct cttcatggtg
    12541 taatgggttg tcaggcttac taattgctta ctatgaggcc tataaagcgg atgctttacc
    12601 aaaagtatca gtaatatctg ttataaatca attgaaaacc ataccgatct catgcgttcc
    12661 tgtcctttgc catgggagtt tgggtgttct cactgcttta gaatatgtcc acgaatcttt
    12721 tccagaagaa acaaaaatac tgattcataa tataaaaaat acattttgtt ccccaacata
    12781 tatctatgaa tattttaaag aagggaaagg tcgatataca ctaagtccag gcttaatgtc
    12841 aggaaaagca ggggcattgt tacacttatg taaactagca aatagtgatt tgaaaatatc
    12901 acctttattg ttaggtgtat aaaatgaaaa attttatttt taaaaataaa agaaaattaa
    12961 aacctactat tcaggtagcc caaacggaat gtggcttatg ttgtgttcga actattttag
    13021 aagcttatgg atgtcataaa aaacttacgg accttagaca aataaaagaa cctggaagag
    13081 atggactcgg cttaactcaa ttaaaagaat tgttaatgca catggggatg gatgttcaaa
    13141 cttataaaat caaagacttg agagcttttg aagttgtaga ttttccgata attgcttttt
    13201 ggaaaggata tcactttgtg tgcatagaat tattcagcga aaaatatgtt atcattatgg
    13261 atccgtcaat aggaagaata aaaatatcaa ttaatgaatt tcaaaaagat ttttctcagt
    13321 atatcttagt agctaaaccc aataaaaact ttgtaaaagt taaaaaaaat aaattagata
    13381 cttggaaaaa agactacatt tggccgaata atatgatgag tctctatcta ggtttgctaa
    13441 tgactagtat tattttagta attatgactt tatctattcc tatatttaca caatcgttga
    13501 tagataagag tagttactta aattctatat cgtttgtaaa aacaatagaa ttactactat
    13561 tagcaataat tacgatgatt ggtctaaaca ccttcagaag ttacctttca attaaaatta
    13621 gttacaaatt caattggcat ttattagttg gagctttcgc acatacctta tcattacccg
    13681 ctaaattttt tacagtacga tctccaggag aagttatttt tagattaaat tcattgacta
    13741 gaattcaaga tgttttagga attactttgg tacaaacttt tctggacata gttagtagta
    13801 ttgtaatact tggatatatt ttttggagtt cttggacttt gggaattatt atcgtcacat
    13861 taataatgtt tatgttttta tttttgatta taactcaaaa atatgtagac tctgcaacag
    13921 ataaagaatt gcgtgaagga tctagtgttc agagtatcca attagatgct ctagcttcta
    13981 taaatagtgt aaaactaggg ggctatgtac agtcgtattt ttctgattgg aaagataagc
    14041 ttacaaaact tttatctgct tcttcacata ggatgtatct tcaacaaggt attgttggat
    14101 ccgttttata tggaatgcaa actatttttc ctttaattat tcttgttatt agtctatatc
    14161 aggaaaaatt agggacatta tcattaggtc aagtaatagc tattcaatcg actgttagta
    14221 tgttatttaa ttattcaaat acaatattta gtaccctttc aaacattatg gtggtagaac
    14281 gatatattga gttatctgag gatatatttg actatcctat tgaatcaagt gttagaagtg
    14341 atcatattat ggagtctgga aatctttcga taaataattt gtattttcaa tatacttctg
    14401 atacaaaacc agcgttgaaa aatattaatt taaaaatatt ggatggagaa acagttgctt
    14461 ttgtaggtgt atccggatcc ggaaaaacaa cactagccaa aatatgtagt agtttatttg
    14521 aacctactaa aggagatata tttttttcag atattaattt tcaacgatat aaccttgatc
    14581 aattaagaaa atcaattagt tatattcctc aagaggctca tttgcataat cgcacaataa
    14641 tagaaaattt gaaattagga agtcaattaa gtgaagaaaa aataattgaa ttatgtagtt
    14701 ctttagaatt tttatctttt atttctgatc taccaatggg atacaatact gtaatttctg
    14761 aaatgggagc aaatttatct ggtggacaaa gacaaagaat tcatatcgca cgagcaattc
    14821 ttcaaaatcc taaaatacta atcatggatg aggctacatc atcattagat aatatttctc
    14881 aaagttctgt atatacagaa ctatctaaac tagagtgtac aaaaatagta attgcccatc
    14941 gtctagaaac gattctaaat gctgataaaa tatttgttct tagagacgga gaaattgtgc
    15001 aaacaggtca ccataatgat ctagtccaac aacctggaga ctataaggat ttatttaata
    15061 cggtaattga aaaggagaaa taactgtgca caatgataat aaattagtta atattataga
    15121 agatatcttt aaagatatag ttgaacacac acacactacc ttaaaaagat cttttacaac
    15181 atttcaagaa aaagaaacag aagtttttat aaagtgtttt catgctttaa tagaatatca
    15241 tataaataga gtcgttcaga aaacatttat ttacgaattc catgaatttc gaaagagttt
    15301 aaatatgcct gctaatccaa attcttccgt tgcatttgat ctgtttttac agaaactgga
    15361 taaacaaatg gttgaaaaat ggctaaacaa atacagctat ttaagaacaa ttattcatac
    15421 aattataaat aatacaagct tatatattat agcagtatgc aaaaatttta aggaagatat
    15481 agatcaatta aataataatg agatgattag taaaaattct tatttaactg ctataaatgc
    15541 attagattct gatccgcaca atggttcaaa aatcgtttta tgttttgaat tttcaaatga
    15601 agaaaaaatt ttatataaac cccgttctct agaaatagac caattaatag acacgatatt
    15661 ttctgatatt ctaaagttta aagggctcaa atataataca ccaattgctc aaacaatatg
    15721 tcgaaatagc tatggttggc aaaaatttat ttctcatact tttattgatg aggcagactt
    15781 atcagaagct tattataatt tggggctgtg tgcagcagta ttcagaagta ttggtgccac
    15841 cgatttacat gatgaaaatg tgatttttaa cggaactact ccttatttca ttgatttaga
    15901 aactagttta aaaccatcac acgaagaaat aaatgaggat tctatatggg acgtattaaa
    15961 taaagaactc tctaattcta ttgctaatac ttgtataatt ccagctaagt taatggtagc
    16021 accacataat atcttaattg gggctattaa tacaccttat ccacaaaaaa cagaagaatt
    16081 atgtttcact ctgaccaatc caggaactga tgcagtagat atatctaaac aaaatattat
    16141 agtttctaga gattcagctc ctataatgtt agaaaaaaat aaatttccta gccctcttcc
    16201 ataccagcaa gactttgtta acggctatga agaaggtatt aaatctgtaa tagtaaatcg
    16261 tgaaaagatt agtgatttat taagtagttt tccttgcacc agtagaataa ttgtgagacc
    16321 aactgttcaa tattttttct tactggatgc atgtttgtat cccgaaaatt taattgatga
    16381 gtctgctata gataaaatat tatcttatat gaagccttct aaaatgttta cagaatcgga
    16441 aaatgcaagt aaagtacttg aggcagaaaa aaaagcttta aaaaaaggag atattccgta
    16501 tttttcaatt gggtcgaata agcatacaat taatttaatg aacataaata ccaatacatt
    16561 tgaaatgtct ccaatagaaa atgctttata ttctttaaat aatctttctg atcgggcact
    16621 tttaattgat aaacgtttaa ttgcagaggg gttttctgaa attaggattc atgaagcaac
    16681 atttgaaaat aataaaacta aaaaatcaca agctaaaatg ttcactgatg ttttaaaaga
    16741 agtgacaata gacaacccag atgcattatt taagttaata ataaatcaat ctattactac
    16801 aaaatctaaa aatgctgaaa caggttggtt aaacggtgtt tatggagaca tgaatattgc
    16861 ttacaattct atatcatgta tttcgttgca tgatgctggt ggtattttat ttctacttaa
    16921 acatttaaca gaatataaaa aatgcgttga tgatatagaa acaaatgaat tatatattcg
    16981 tgcttctaaa ggtgtcaact ctcttaaaaa tactatttat ggttctacag aagtttcaaa
    17041 taccccaatg tcaattattt caggatcaaa ttctcttgaa tttctgttta accatgaaca
    17101 aaaaaaactg aaatatcttg ataagactat atcaaaaatt caattagaga atattgaaag
    17161 tggagatgtt tttttaggtc caataggtat tgcattagta aatgctactt ttcctaatac
    17221 gtctatcgat aatatcattt attttacaga aaaattccat aataccaaat tacctagtga
    17281 aggaatagct cacggaaatc taggtgtttt atggacaaat ttcagattaa attatgcctt
    17341 ggacagatta gatatatgta aaaatatatt tcatgaaacg actcggatta agtttgagga
    17401 atctgttgaa aatgttggat ggtgcaacgg aaattcgggt ctattaatgg tactgacaga
    17461 aatggctact ttattaaaag ttgacataaa tttatttgat ttggccaaaa aatctactat
    17521 tcttccatta gaaactcctt tagatttatc aatctgtcat ggagtatcag gtgttcttca
    17581 atcactgctt ttttccttta aagtttcaaa aaaatctgag tatataatgc tagctaacga
    17641 gtattggtta tccgtcctta aactaataga cataaatggt tactatacag gtgaaaaaaa
    17701 cagggattat ttacttggat attttttagg ctggagtggt atggctgatt cagcactatt
    17761 attaaaaatg tacaatgaag ggtcctctcc tttgattcct ctaaatttga gttccttaga
    17821 ttatcagaaa aagctgatgg aggtgtaaac tatgaaagcc ctagttgcaa taaatcccag
    17881 atacaaaaat tcattagagt ttaaaaaaat ggaaacagtt aaattcggat ctactaatgt
    17941 tctatttgga ttagtagagt taaatcaacc cgattttgat ataaataatc ttcaaaatga
    18001 tgattatata ttaataaaag ttaaatattt ttcttgtaac tatagagata aatctatctt
    18061 attagaagcc tatacttctg aaaaaaacga aaatagatta ttctttccat ttggttcaga
    18121 atttagtgct gaaattatta agattggaaa aaatgttaat aatttcaatg ttggagattt
    18181 tgtcatgcca aactgcgaat atcctcatgg agtaaaacca ggaataccga gtaattttgc
    18241 atctttagga tggttaaaaa ttcacaaaag taaagttatt aaaattccag cacgtctaag
    18301 tcttgaagaa gctgcatgtt tttctttagg ctcacaaact gcttccagta tgattagacg
    18361 atctaatatt ttgaaagaaa gtggtaatcc agtagttttc agcgcacgct ctgcaacttc
    18421 tatgtttatt attcgtcaac tacttataca aggaattaca cctatatgta tatctactac
    18481 ttcatggaca gattttgaaa aagaatatat atatccttgt gaggtggaac gtttagaaga
    18541 cgtatctttg caagctatga agcgaaatat tacgcacgtt tttgatcctt tttttgatct
    18601 taatgtagaa aatgcagtaa atttattaca aattggaggc acttatataa cttgtgggct
    18661 tttaaatcaa caccctcttt tatctgagaa aatacctata gaaaatgagc caattttaag
    18721 aagagcacta agtatgggag taatgaaaaa tattacattt ataggaaact gcttaggaac
    18781 atatgaagat ttgcaaaatg ctatcagttt agaggaaaga ttctctgtga aacctgtaat
    18841 tgataaatct tataacgtta accaatacct agattttata gatcgttcat tttttaacgc
    18901 taataaaata ggtaaggtgt ctttaaccta ccattaatta cagtgtacta aaaatttaaa
    18961 attattcaga tttttagtac atttaacttt acttttgtta aactttactt taatatttgg
    19021 gtagagatgt gaaaaatttg ttaaatttgg ttcaaaagct aggggttttc tctttttcaa
    19081 cacgaaaaaa gatttttgaa tcataactaa ataaaagtaa ggaaagctat gaaaatactc
    19141 ggtagttact tgaataactt caaataattc gtttaagtgc ttttaatttt agttaggact
    19201 gttttttgga taaataatta atctttacga tattctctac atcgttttat cagttaaaag
    19261 aactggtccc tagtgattat ctttgtctga atactagtat attacttttg taaatttaga
    19321 taacaaagga aaaattttcc cctgaactgc ttatgaatac taagtttaaa cgtttttcac
    19381 acggttaatt aactataagt agggtgacta tatgaagaaa aaaatacacg aagaatctat
    19441 acgtaataaa gtttacgaat atagagtttt agccagacta tcacaacaag aattagctga
    19501 tagagttggt gtatctaaac aaacaatttt tgttatggaa aagggaaact atgtaccgtc
    19561 gttactatta gcatttcgaa tatcaaattt ttttaatgta ccgcttacag agatttttga
    19621 atacgattta ggaggacaaa ataatgatga ataaatctat tggattttca tttaacgcct
    19681 taaatgaatg gtcagaaaaa agtattggga attataattt acttattggt gttggttttt
    19741 tacttgtaat gattagttct attactttag tatatctgtt attaaagttg ggacaaagag
    19801 atgagcgcac aacaaaaatt catttaaatg tatgttgcta tatgttggta accattgttt
    19861 tgtgtgactt attctttcct aaagaataca tgcaaaatat actattctta ttcaaatatg
    19921 cactagcatt ttctatatct ttaatttact tacttaaaaa atataaacaa gatttatgtt
    19981 aattacttat aaaaatcata ggatgaatat gctgactagc agttaggaga aagaatatga
    20041 atattaataa agtatctaaa tcttataaca atacaagtgt attagataat atatctttca
    20101 attttaaaaa aggtgaaata ataggattag ttggtagaaa tggtgcaggg aaaagcacgt
    20161 taatgaagat tattactgaa aatatcctta actttaatgg atctattatg agaaatagct
    20221 cgataggata tttaattgaa gagccaaaac taatagcaag tatgtctggg ttagaacatt
    20281 taatatattt ttctagaatt tatgggaata aatttgatat aaacgaattc aaagatttat
    20341 tagtaagtct aaatttatat caaatattga ataaaaaggt tagagaatat tctttgggaa
    20401 tgaagcaaaa attagcagtg gttatttcta tcttaaatta tccagattat gttgtactag
    20461 atgagcccac taatggaatg gatgttgaat catcatatga aatgttgaac gctctgaaaa
    20521 aacttgctat taaaacggat ttaggtatat taatttccag ccacaaatta gaagatatag
    20581 aaataatctg tgataggatt ctatttttag aaaatggtgt tcttattgga gaagaaacaa
    20641 ttaatcagag ttcgcaaaac ataataaaaa ttatcttttc caacaatgat gatttaacta
    20701 tgtttatcaa taagcaagaa ttagggaata tttataatgt aactcaagat acgttgacat
    20761 tacagacaag cttaaatagt agtgacgttt ttactttatt agaagagtta aatatattta
    20821 taattgattg tcatactgaa aaaaatactc ttcgtaatat ttatttagat aaatttggtg
    20881 gtgaaaaaaa tgaagtttaa tataacaggg tacgtctcgt ataatctaaa aagactaata
    20941 acgcgtggct atttaccact aggattgatg ataagtatac tcccagcatc tattatgtgt
    21001 tacattattt tagttaattc tgcaccattt acaattaaac atatttcgaa tttctattgt
    21061 atgttaggga taacagcaat ggttctccag tctacgtatt taataaataa tgacttttct
    21121 tacaaaacta ttagtttgat atataattca aaagaaaata gactaggtta tattattggt
    21181 aacatactta tttctatatt tgtaggcgca atattttctg ctattggaat aattttattt
    21241 atcatatcta aatacttagg tgtaccagga aaattagaga taatattttt attaggattc
    21301 atacttgacg taattctagt catagtaatc tattttttat gtggatactg tttattttta
    21361 tcgggatttc gtagtggtgc agtgtatggt atattaatac ttttcttgct ttttatccct
    21421 aatttgcttt ctaatatagt ttatggatat tcaaatcctt ttttatcagc ggtagtagaa
    21481 aattttcctg gctactattt gccgattacc gtaggatcga atgtatttac actattacaa
    21541 tatataatta gtttaataac aatatttgta ttatttacag ttgtattaaa aaaaagttta
    21601 cgggtagaag tttgattaag tttactaacg aaagttgtgt ctcatatgga gtataaagat
    21661 atcattaaat ggttaatact tatgtatata tcctctaaat cagcatcata tttttataaa
    21721 atattggact caacaataat taatatatgg atttctagat taatatgttg tgttgttgcc
    21781 ggaatcatag gtatcatttt acacaaatat tggtttacga ttgtttaaat aggattgatt
    21841 ttttaaattt aaggtgaaaa aaaccttgaa atataaacgt gtaggaatcc aaaatcatat
    21901 cgtaaatttc tttgattgcg tcccaatatt caattatatt ttaaagttac tagtctttct
    21961 atagtggaat tggtagtttt tcaaaatttt tactaattgg attgaataac aaggtgatta
    22021 gagttagagg ttattatgat ttatgaatca acaaggtata tctcaatgtc attaagttaa
    22081 gaaaaatcgt atatacaata gtgtgtaatt gaataaaatt aagttgtaat ttaagtgatc
    22141 tttaacaata cccccctcta gaagacatgt cttctagagg ggggtacaac ttgttctaca
    22201 agaattactt ttttattttt aactggttat attttagaac ttagtattgt tattttgttt
    22261 tacttcttta tcaaaataca aaactggatt aaattcttct ttgttaagtt ctattacttt
    22321 tacataggaa aagcaggaaa gcttaaatgt tttcctgctt tcttaactga atgacactga
    22381 ggcatacctt gtcggttctt tttcatattc tgattgttta caggtaaaca gtaggatatt
    22441 caagttgggc atacgtcatt tgtgtcaatt ttgagtatac tttttttaat ctatttagtg
    22501 tcttgaaaaa gagaatgttt tggttgttat agatatgaag caggaaacaa ccattaaatt
    22561 tccagctcat gttctttgac aactaaataa aaatctatca gtaccttcca tttacgggga
    22621 gcatgtttta gctacgccaa gacaaagaaa aaaattcttc gagcgaataa tttctaaagc
    22681 aacttaactg tcaattaagg ccaagattcg taaatgaact aatgatactt ccgtgaggct
    22741 cgccataacg aggggagagg tgaaattcct atgatgcttt tgacaaaagc agctgataga
    22801 tttaaagaga tatttatcat atagaaagaa aaataaacaa tttaaactga atggatgaaa
    22861 gaagtgaaaa aattggaaca agtgatagaa tatagtgctc aaatactctt accgaaaaat
    22921 ttcattctaa ttcaaagaga ggagtacgat catttaataa gagcgggttt taaaggaaac
    22981 tgtatttctg tagaagcgtt taggaaaaaa catacttgtt taagtcgacc aatgtttaat
    23041 gaacgaattc ttttaaatcc gagatttaaa aaaatcttag atataagaga aaatcccaat
    23101 ggttgtgtct cgtatccaaa aggtggtagt gctggcaaat attatatatt agaaagtaag
    23161 atgttaatgt ttattgaaga gtatttttcc gagattttta ccagttttca gatagatgcg
    23221 gtataattat tttgaccata gctatttaaa agcccttttt aaaagaggcg atttaaatgg
    23281 gaattagcaa acgaggaaca aagtggcgtg cttttgtaag cgtaaaaaag gaaggcggaa
    23341 aatacagaaa taagacctta ggtagttttg ataccaaatt tgaagcggta aaagcagtgg
    23401 aacatgcgca atccgtcgct tcaaaagatc gacgtatggc gtttacgctt cctttttatg
    23461 agtattttga atggtttttt caaaaatata aaaaagaagc ttgttccaaa aaaacgcaag
    23521 gacactatca gcatactaaa agatatatta aaaggtattt aggtgataca ccattatctg
    23581 acttaacaaa tgataagtac gtagaataat taaatcggtt ttctaaagac tattcgccag
    23641 ctactttaga aaagtttcat actcatatgc gtgcttgtgt caaacaggct tttgctttgg
    23701 ggcatattcc tattgagttt acttctggta gttctttgag aggacttgga gataagtcta
    23761 aagaaaaacc gatttatcaa aagtatattg atgatactca gtataaaaaa gttttacagt
    23821 atgttgttca acatagagat aaagaatctt ctatttatta tgtaatcatc ttttctctac
    23881 ttacaggttg ccgtttttct gaaatagttg ggattacaat tgatgattta aactttgaac
    23941 aagggtttgt agatataaac aaaacttatg atcatatgaa tccgccgtct aattcaagcg
    24001 attggcttcc ttgtaaaaat aaaaatagct atcgtaaggt agaaatgcca cagaacttgg
    24061 cagaactctt gcaagagttt tggcaatatc aacagaaaaa atgccagttt catcaaatta
    24121 aaaatccacg taaacaaatt ttctttgatt ggcaagaagg tgcctgtgac aaccgaaagg
    24181 ccaatattga gattaaaaaa attcttgtga catgtggcat aactgataaa ccaaaatttt
    24241 ctatgcattg ttgcagacat acttttgttt cttttttaat ctatcaaggc tattcagtag
    24301 aagaagttgc tttaattgtt ggagataaac cagaagaaat aagaaaaaca tactatcatg
    24361 tctttcagga atatgaagtt agaacacgat ctaaaacgcg caaattgatg aattcactct
    24421 tttaatttgt tatttaatac taaattagct ggtgcaaaga tggtgcgaga aaatgaaaaa
    24481 tagttaaaag tatttaaagt gaaacgttga aatgacagtg tttataaagt atttgacggt
    24541 attttaggta aacaatctct ggccgccggt atactaaaga ctgttaaatc attgatttaa
    24601 cagtcttttt cgttattatt ttctagaata cataaaaaaa accatctcaa aaaaatgaga
    24661 tggaaagtta agtgagagag tgataagtat agtgcgaata aatacaaggg ttacagaaga
    24721 atgtgggggt tctgcatcat cgtcattaaa tgttcctgca gtaggaatat gaatttctgt
    24781 catattatat tcaataactt gaactgtgat gattgcaaca gttccaatga ttgctaacat
    24841 agtagtcata ctttcactcc tctcttaatt ttaaataaaa gtacttaact gattgactag
    24901 agactaaaaa gatacatcaa catgaacgtt gagctttagc actatacaac gtaaagatca
    24961 ctcttagcta ttttgagaaa agccttctcc tcgaccagtc ttgttctact cattggtgtc
    25021 tctcgacatt tctgagcaat agcctatgtt tgtataggag cctcacctaa cttattacaa
    25081 agaaataata gtcttttaag taactctttg tcaagacata agcagaagtc aaaacagttc
    25141 tatttacaaa tgaatgcgac gaaccatttc ttctgttatt tgttctacaa tatcaatggt
    25201 tgtttttggc gaacgttgat ttctggggat atcgattgag taaattttgg caatacgacc
    25261 aggatttgca tccattaata caacccgatc agaaagttga actgcttgtt gaacatcatg
    25321 cgtgatcatc acaattgatt tagtcgcaat ttgattgttt agccaaattt ctaataaatc
    25381 gttagataat tggctggctg taatgatatc taaagctgaa aaaggttcgt ctaagagcaa
    25441 taagctaggt tcgatggcta aagcacgagc aaagcctaca cgctgtttca ttccaccaga
    25501 taactctctg ggataagctt tttcaaaacc agttaaacca atcatttcaa tgagattact
    25561 gactctttta tttatttgtt cacgggaaat ttctttacgg ttttctaagc caaagctgat
    25621 atttttttca actgtcaacc aaggaaaaag ggcaaaatgt tgaaaaacca tgccgatatt
    25681 ggcatcaggc tcattaatga ttttatcttc aaaagtaatt tcacctctag ttgtacgaag
    25741 aagtccagcg atacttctga gcaacgttga ttttcctgtt cctgattgtc cgataatact
    25801 taaaaattca ttcgttttaa ctgttaaatc aatattttca aggactttta aatgttctga
    25861 atgtccttca atttcaaatt ctttatatac tgattttatg cttaataatt ctttattttc
    25921 catcgtctta ttagataggt caaggtaaat cacctatcgt tctcctctct agtttatctt
    25981 aaaaatttag tcgagttgag tcgtccagct attaatagtg aaatttttgt tttgctgctc
    26041 gatataaagg ttgccaaaca aaggcgatac ataaaccaac aacgaaacac atcgctaagg
    26101 ttcctaaggc agatttatct tttacgccat cgtttgccgc aatatattgt cctaggccag
    26161 taacatctat tgattttttg ccccattgaa tgctttctgc tgcgatatca gcgttccaag
    26221 cagcaccagc agcgttaata attgctgtaa tgaggtaagg taaaatagaa gggatcaaaa
    26281 attttgtcca ccattgccat ttagataatt taaaaagttt ggtcacgtca cgaatatcat
    26341 cagggatggc taagtagcca gcaattacat taaagaaaaa ataccattgg caaccaacca
    26401 tgatgagtgg taaaatccac cattctaatt tgttgaagcc catactaata atcaacacaa
    26461 tgaatggagt ataaacattt gacggaatgg agcctaaaat ttgtccaatc ggttgaacga
    26521 tacttaagcg ccgattatca ttcgcaaccc agattgctaa gggagtaaag ataatgccag
    26581 caacgaccat ggccaaggta acccgtagtg tagtataaag ggttaatcta ggaatcatgc
    26641 tgaaatcttg atggggcaag aaatgataga gcttaataga acaataaacc ccaataatgg
    26701 ttaagctgac ataccataat gttttgaaga aatggcgtaa ttttgctagt aatcgataga
    26761 gatagtctag cttgaaaaag taccaaactt ttggtaaatc gtaaatccaa aaatgactga
    26821 atttcacaaa agcttttgaa aagtatttcg ttaaagttgc tttttttaat aaatgataaa
    26881 tgatggattt aggtggcgtc gtactttcga catctgtttc atatttaaaa taataagtgg
    26941 ctcgaactaa aggttgaaaa actaaaaagt ttaaaatcac cacattgatt aataaggcaa
    27001 aaacagccca taaacaggat ttaaagtcgg ctcgatttaa tgctacttgg atataagaac
    27061 caattcctgg taaataaagg ttggtttctt taggaaaggc aacagaagct tgctcgctgg
    27121 ccaccaaggc aaaccaagcc gcagtttgag aaataataac gttccaaagt aagccaggaa
    27181 ttgagtaaac aaattcaaga cgccaaaatt tttcccaagc attgtacttg aactgatcgg
    27241 tcacattgac tagatctgaa ggaataactt ccattatttg ataaagagtc aacatgatgt
    27301 tccaagcttg acctgtgaag atggcaaaaa tagcaaccgc ttctgcgccc atcacatttc
    27361 ctggaaataa accaagtaac caagcagttg taaaggtcaa aaagcctagt aatggaacgg
    27421 attcaaggaa attaactaat ggtaaaatga ctcttcgtgc cgttttatat tttacggcta
    27481 aaataccaaa aataaaggaa aacaggaagg accaagccat acccacaatc attcgaaaca
    27541 tggttcgaat tgaaaagtaa aaaagatttg atggagataa gaaatcatct gttttacttg
    27601 gtgttgcgag gaattcttct gagggaaggg tgtggagagg gcgattcatt tttagccaag
    27661 agaagacgat gataaaaatg aaaatgccta aaatgatgag caaggtaaga ttcccgatac
    27721 ttttagcaag tagggtattt ttcttagatg atgcagtgac agctttcaat ttaaaaacct
    27781 ccaattaatc atattaaaga ggtcgccgaa taaaagaaga agattatagg gtaatcacaa
    27841 taattgag
//
