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Overview
1.1
1.2
1.3
1.4

### Identified secondary metabolite regions using strictness 'relaxed'

NZ_CP092907.1 (Enterococcus faecalis)

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene,NRPS | 333,051 | 377,347 |
Region 1.2 | terpene-precursor | 724,697 | 745,578 |
Region 1.3 | lanthipeptide-class-ii | 814,386 | 842,233 | Low | staphylococcin C55 α/staphylococcin C55 β | ribosomal:RiPP:Lanthipeptide
Region 1.4 | cyclic-lactone-autoinducer | 1,566,535 | 1,587,263 |

Region | Type | From | To | Similarity Confidence | Most similar known cluster
--- | --- | --- | --- | --- | ---
Region 1.1 | arylpolyene,NRPS | 333,051 | 377,347 |
Region 1.2 | terpene-precursor | 724,697 | 745,578 |
Region 1.3 | lanthipeptide-class-ii | 814,386 | 842,233 | Low | staphylococcin C55 α/staphylococcin C55 β | ribosomal:RiPP:Lanthipeptide
Region 1.4 | cyclic-lactone-autoinducer | 1,566,535 | 1,587,263 |

No secondary metabolite regions were found in these records:
  NZ_CP092908.1 (Enterococcus faecalis)
  NZ_CP092909.1 (Enterococcus faecalis)
  NZ_CP092910.1 (Enterococcus faecalis)

Compact view
NZ_CP092907.1 - Region 1 - NRPS,arylpolyene
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 333,051 - 377,347 nt. (total: 44,297 nt) Show pHMM detection rules used
arylpolyene: (APE_KS1 or APE_KS2)
NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
NRPS/PKS modules
NRPS/PKS domains
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase oxidoreductase
MK744_RS01785: short-chain dehydrogenase/reductase SDR

smcogs
  SMCOG1001: short-chain dehydrogenase/reductase SDR

MK744_RS01840: aldo/keto reductase family oxidoreductase

smcogs
  SMCOG1039: aldo/keto reductase family oxidoreductase

Transferases: PPTase transferase
MK744_RS01740: 4'-phosphopantetheinyl transferase

smcogs
  SMCOG1012: 4'-phosphopantetheinyl transferase

MK744_RS01815: acetyl-CoA carboxylase, carboxyl transferase,

smcogs
  SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

MK744_RS01820: acetyl-CoA carboxylase, carboxyl transferase,

smcogs
  SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

Lyases: decarboxylase
MK744_RS01865: Decarboxylase, pyridoxal-dependent

smcogs
  SMCOG1180: Decarboxylase, pyridoxal-dependent

Ligases: ligase synthase
MK744_RS01805: Beta-ketoacyl synthase

smcogs
  SMCOG1022: Beta-ketoacyl synthase

MK744_RS01810: AMP-dependent synthetase and ligase

smcogs
  SMCOG1002: AMP-dependent synthetase and ligase

Translocases: permease
MK744_RS01870: phenylalanine-specific permease

smcogs
  SMCOG1038: phenylalanine-specific permease

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | arylpolyene | NRPS | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | --- | ---
BGC0001261.3 |  |  | 0.58 | NRPS | AM-toxin | Alternaria alternata
BGC0001166.5 |  |  | 0.57 | NRPS | HC-toxin | Alternaria jesenskae
BGC0002286.3 |  |  | 0.54 | NRPS | ririwpeptide A, ririwpeptide B, ririwpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002008.3 |  |  | 0.38 | other (other) | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.5 |  |  | 0.38 | other (other) | APE Ec | Escherichia coli CFT073
BGC0000837.4 |  |  | 0.37 | other (other) | APE Vf | Aliivibrio fischeri ES114
BGC0000888.5 |  |  | 0.34 | other (other) | bacilysin | Bacillus sp. CS93
BGC0001928.2 |  |  | 0.33 | other (other) | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0002518.3 |  |  | 0.32 | NRPS | syringafactin A, syringafactin C | Pseudomonas sp. SZ57
BGC0002547.2 |  |  | 0.32 | PKS | youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4 | Streptomyces youssoufiensis

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001261.3 |  | 0.63 | NRPS | AM-toxin | Alternaria alternata
BGC0001166.5 |  | 0.62 | NRPS | HC-toxin | Alternaria jesenskae
BGC0002286.3 |  | 0.61 | NRPS | ririwpeptide A, ririwpeptide B, ririwpeptide C | Photorhabdus laumondii subsp. laumondii TTO1
BGC0002008.3 |  | 0.51 | other (other) | aryl polyenes | Xenorhabdus doucetiae
BGC0000836.5 |  | 0.51 | other (other) | APE Ec | Escherichia coli CFT073
BGC0000837.4 |  | 0.50 | other (other) | APE Vf | Aliivibrio fischeri ES114
BGC0000888.5 |  | 0.49 | other (other) | bacilysin | Bacillus sp. CS93
BGC0001928.2 |  | 0.48 | other (other) | (2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid | Streptomyces sp. MA37
BGC0002518.3 |  | 0.47 | NRPS | syringafactin A, syringafactin C | Pseudomonas sp. SZ57
BGC0002547.2 |  | 0.47 | PKS | youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4 | Streptomyces youssoufiensis

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.27 out of 26.06
Confidence: strong
RpoN
Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 17.55 out of 18.46
Confidence: strong
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.93 out of 30.25
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.54 out of 26.06
Confidence: medium
FuR variant 2
Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 29.42 out of 32.74
Confidence: medium
FuR variant 1
Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.37 out of 29.38
Confidence: medium
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 24.31 out of 30.25
Confidence: medium
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.99 out of 30.25
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 25.28 out of 27.78
Confidence: strong
CatR
Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 21.07 out of 25.31
Confidence: medium
Additional weak hits (3):
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 23.10 out of 36.53
Confidence: weak
NrdR
Description: Represses ribonucleotide reductase encoding genes
Species: Streptomyces coelicolor
Score: 19.58 out of 27.18
Confidence: weak
LexA variant 1
Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 23.73 out of 29.65
Confidence: weak
Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
NRPS/PKS products
NRPS/PKS substrates
TFBS Finder
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 333050 - 377347:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (X)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).
MK744_RS01810: X
AMP-binding (15..416): X
nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:
  Predicted physicochemical class:
    hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
  Large clusters prediction:
    Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
  Small clusters prediction:
    N/A
  Single AA prediction:
    N/A

Stachelhaus prediction details:
  Stachelhaus sequence:
    LGMAFDPSIAQFDIISCGEFNFYGPSECSVYSTV
  Nearest Stachelhaus code(s):
    Cap DPQDIGIVNK (50% 8Å match)
  Stachelhaus code match:
    60% (weak)

Link to PARAS substrate predictor
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CatR | H2O2-responsive repressor
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
ColR | Phenol-responsive regulator
FuR variant 1 | Ferric Uptake Regulator
FuR variant 2 | Ferric Uptake Regulator
MogR | Repressor of flagellar motility genes
RpoN | Regulator of nitrogen assimilation and virulence

NZ_CP092907.1 - Region 2 - terpene-precursor
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 724,697 - 745,578 nt. (total: 20,882 nt) Show pHMM detection rules used
terpene-precursor: (PT_FPPS_like and not PT_HPP)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Terpene
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Hydrolases: peptidase
MK744_RS03515: methionine aminopeptidase

smcogs
  SMCOG1172: methionine aminopeptidase

Ligases: synthetase
MK744_RS03550: Polyprenyl synthetase

smcogs
  SMCOG1182: Polyprenyl synthetase

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | terpene-precursor | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0002309.2 |  | 0.36 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000639.3 |  | 0.34 | terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000642.3 |  | 0.34 | terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0001605.3 |  | 0.32 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001075.5 |  | 0.31 | PKS, terpene | aurachin RE | Rhodococcus erythropolis
BGC0001456.3 |  | 0.30 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000286.3 |  | 0.30 | PKS | viguiepinol | Streptomyces sp. KO-3988

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0002397.2 |  | 0.47 | terpene | astallatene | Arabidopsis thaliana
BGC0002400.2 |  | 0.44 | terpene | boleracene | Brassica oleracea var. oleracea
BGC0002398.2 |  | 0.39 | terpene | (-)-ent-quiannulatene | Arabidopsis thaliana
BGC0002309.2 |  | 0.36 | terpene | cattleyene | Streptomyces cattleya NRRL 8057 = DSM 46488
BGC0000639.3 |  | 0.34 | terpene | carotenoid | Enterobacteriaceae bacterium DC260
BGC0000642.3 |  | 0.34 | terpene | carotenoid | Enterobacteriaceae bacterium DC413
BGC0001605.3 |  | 0.32 | terpene | gibberellin | Sinorhizobium fredii NGR234
BGC0001075.5 |  | 0.31 | PKS, terpene | aurachin RE | Rhodococcus erythropolis
BGC0001456.3 |  | 0.30 | terpene | isorenieratene | Streptomyces argillaceus
BGC0000286.3 |  | 0.30 | PKS | viguiepinol | Streptomyces sp. KO-3988

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Detailed terpene predictions
Detailed information for terpene domains. Shows possible products of a terpene cluster and lists the subtype and expected reactions for each terpene-related domain.
Product predictions:

Class | Subclass | Product name | Chain length | Initial cyclisations | Functional groups
--- | --- | --- | --- | --- | ---
sesquiterpene precursor |  | FPP | C15 | acyclic | PP

Genes with terpene domains:
MK744_RS03550: PT_FPPS_like
Domain 1 (29 - 276): Prenyltransferase; Farnesyl diphosphate synthase like
Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:
  IPP, DMAPP → FPP

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.25 out of 27.78
Confidence: medium
CodY
Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 22.38 out of 27.78
Confidence: medium
ZuR variant 1
Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.87 out of 28.19
Confidence: medium
Terpene
TFBS Finder
Glossary
Glossary showing acronyms and their full names.

Acronym | Full name
--- | ---
DMAPP | Dimethylallyl diphosphate
FPP | Farnesyl diphosphate
IPP | Isopentenyl diphosphate
PP | Diphosphate

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CodY | Regulator of stationary phase and virulence in Gram-positive bacteria
ZuR variant 1 | Zinc-responsive repressor

NZ_CP092907.1 - Region 3 - lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 814,386 - 842,233 nt. (total: 27,848 nt) Show pHMM detection rules used
lanthipeptide-class-ii: cds(LANC_like and DUF4135)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
Lanthipeptides
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
Oxidoreductases: dehydrogenase
MK744_RS04010: crotonyl-CoA reductase / alcohol dehydrogenase

smcogs
  SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase

Lyases: cyclase
MK744_RS03995: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

MK744_RS04005: lanthionine synthetase C family protein

smcogs
  SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | lanthipeptide-class-ii | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000520.5 |  | 0.78 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000555.3 |  | 0.70 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001229.4 |  | 0.63 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0002110.3 |  | 0.59 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0001391.3 |  | 0.55 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000525.5 |  | 0.53 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0000517.4 |  | 0.51 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001555.4 |  | 0.51 | ribosomal | colicin V | Escherichia coli chi7122
BGC0001210.5 |  | 0.51 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0002663.2 |  | 0.51 | ribosomal | amyloliquecidin GF610 | Bacillus amyloliquefaciens UMAF6639

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0000520.5 |  | 0.78 | ribosomal | lacticin 3147 A1, lacticin 3147 A2 | Lactococcus lactis
BGC0000555.3 |  | 0.70 | ribosomal | staphylococcin C55 α, staphylococcin C55 β | Staphylococcus aureus
BGC0001229.4 |  | 0.63 | ribosomal | SBI-06990 A1, SBI-06989 A2 | Streptomyces bingchenggensis BCW-1
BGC0002110.3 |  | 0.59 | ribosomal | birimositide | Streptomyces rimosus subsp. rimosus WC-3908
BGC0001391.3 |  | 0.55 | ribosomal | thusin | Bacillus thuringiensis serovar rongseni
BGC0000525.5 |  | 0.53 | ribosomal | lichenicidin VK21 A1, lichenicidin VK21 A2 | Bacillus licheniformis
BGC0000517.4 |  | 0.51 | ribosomal | haloduracin β, haloduracin α | Bacillus halodurans C-125
BGC0001555.4 |  | 0.51 | ribosomal | colicin V | Escherichia coli chi7122
BGC0001210.5 |  | 0.51 | ribosomal | pseudomycoicidin | Bacillus pseudomycoides DSM 12442
BGC0002663.2 |  | 0.51 | ribosomal | amyloliquecidin GF610 | Bacillus amyloliquefaciens UMAF6639

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.
Location:
Identifier
Identity
Coverage
Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for MK744_RS03995

MK744_RS03985
Leader:
MRDEENNETLINNEQVAWFEEVADQSFDDDVFGA
Core:
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
Core with dehydrations:
Cys Dhb Dhb N Dhb F Dha L Dha D Y W G N K G N W Cys Dhb A Dhb H E Cys M G W Cys K

#### antiSMASH-DB 4.0 matches for MK744_RS03985

100.0%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide
Lanthipeptides: PO853_RS06515_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
93.3%
NZ_BLIS01000009.1 and 7 others:
NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide
Lanthipeptides: GVO03_RS04820_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N K G N W C T T H E C M W C K
1
C T T N T F S L S D Y W G N K G N W C T L T H E C M N W C K
30
93.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide
Lanthipeptides: IE339_RS06330_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N K G W C T A T H E C M W C K
1
C T T N T F S L S D Y W G N K G G W C T A T H E C M S W C K
30
with 105 more sequence matches
Only the first 10 are displayed here.
93.3%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide
Lanthipeptides: CQS04_RS09620_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N G N W C T A T H E C M W C K
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
86.7%
NZ_FMPI01000012.1 and 1 other:
NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide
Lanthipeptides: BJR39_RS08305_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N G N W C T A+H E C M W C K
1
C S T N T F S L S D Y W G N N G N W C T A S H E C M S W C K
30
86.7%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide
Lanthipeptides: CN977_RS23160_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N G+W C T A T H E C+ W C K
1
C T T N T F S L S D Y W G N D G S W C T A T H E C L S W C K
30
83.3%
NZ_CACZYW010000004.1 and 1 other:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide
Lanthipeptides: HUF10_RS02825_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N G N W C T +H E C M W C K
1
C S T N T F S L S D Y W G N N G N W C T L S H E C M A W C K
30
83.3%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide
Lanthipeptides: allorf_0097945_0098112_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N+G W C T T H E C M W C K
1
C S T N T F S L S D Y W G N R G Y W C T L T H E C M S W C K
30
83.3%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide
Lanthipeptides: EI692_RS18440_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N K G W C T +H E C M W C K
1
C S T N T F S L S D Y W G N K G G W C T I S H E C M S W C K
30
83.3%
NZ_QGEE01000020.1 and 5 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide
Lanthipeptides: DKP74_RS06160_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N+G N W C T +H E C M W C K
1
C S T N T F S L S D Y W G N R G N W C T L S H E C M A W C K
30
80.0%
NZ_CP016767.1 and 11 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13410_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15325_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15325_lanthipeptide NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07920_lanthipeptide NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07920_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00580_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00580_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17015_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17015_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04645_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04645_lanthipeptide
Lanthipeptides: BCV50_RS13410_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C
29
C T T N T F S L S D Y W G N K G W C T + E C M W C
1
C T T N T F S L S D Y W G N K G G W C T V S K E C M A W C
29
80.0%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N G C T T H E C M W C K
1
C S T N T F S L S D Y W G N N G W L C T I T H E C M S W C K
30
80.0%
NZ_FNHR01000005.1 and 1 other:
NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide
Lanthipeptides: BLQ37_RS05590_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y G N G N W C T +H E C M W C K
1
C S T N T F S L S D Y M G N N G N W C T I S H E C M A W C K
30

#### MIBiG 4.0 matches for MK744_RS03985

63.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C
29
C T T N T F S L S+ G N G W C T T E C C
1
C T T N T F S L S N A L G N N G G W C T L T K E C Q P N C
29
40.0%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
F S L S D Y W G N K G N W C T A T H E C M G W C
29
+++S G N K G +C T T E C M C
4
Y N I S C R L G N K G A Y C T L T V E C M P S C
27
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
C T A T H E C M G W C
29
C T + E C C
28
C T L S K E C Q P N C
38
MK744_RS03990
Leader:
MNNDKQNEPNVDLELGKYLEADLISLTDDEVTGG
Core:
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
Core with dehydrations:
G Dhb P Dhb I Dhb I P I Dha I A V Dha G W I Dha D K Dhb Cys P Dhb Dha V Cys Dhb R A Cys

#### antiSMASH-DB 4.0 matches for MK744_RS03990

100.0%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
61.3%
NZ_CP051884.1 and 3 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide
Lanthipeptides: HGK68_RS15130_lanthipeptide
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
G T P T+ + I V S W I S+ T C P+S C T R A C
1
G T P T V V L S I---V S A W I S N N T C P S S A C T R A C
28
61.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
2
T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P T I I A V+G+I S T C P T+ C T R A C
2
T P T I V I---T A V T G Y I S T N T C P T T S C T R A C
28
with 77 more sequence matches
Only the first 10 are displayed here.
61.3%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide
Lanthipeptides: CN977_RS23165_lanthipeptide
2
T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P T++I ++ A V S G+I S T C P T+ C T R A C
2
T P T V S I A L T-A V S G Y I S S N T C P T T A C T R A C
30
54.8%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: C3B71_RS16030_lanthipeptide
Lanthipeptides: C3B71_RS16030_lanthipeptide
2
T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P + +A V G+I S T C P T+V C T R A C
2
T P A V A T A A L L A V G G F I S H N T C P T T V C T R A C
31
54.8%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
5
I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
+T I S I V S G+I S T C P++ C T R A C
1
V T P A I S I L V S G F I S T N T C P S T A C T R A C
27
54.8%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P T I I A++G+I S +C P T+ C T R A C
1
A T P T I V I---T A I T G Y I S A N S C P T T A C T R A C
28
50.0%
NZ_CACZYW010000004.1 and 3 others:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide
Lanthipeptides: HUF10_RS02820_lanthipeptide
8
P I S I A V S G W I S D K T C P T S V C T R A C
31
P+ +A V S ++S D K T C P T+ C T R A C
9
P V I V A V S A Y V S D K T C P T T A C T R A C
32
48.4%
NZ_KE384533.1 and 2 others:
NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide
Lanthipeptides: K329_RS31315_lanthipeptide
2
T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P T I I + V S ++S T C P T+ C T C
1
T P T I V I S V---V S A Y V S T N T C P T T S C T D E C
27
42.4%
NZ_LR134317.1 and 1 other:
NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide
Lanthipeptides: EL136_RS01690_lanthipeptide
7
I P I S I A V S G W I S D K T C P T S V C T R A C
31
+ S+A V+ +I S T C P T+ C T R A C
9
V K A S V A V T A F I S A N T C P T T S C T R A C
33
42.4%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
12
A V S G W I S D K T C P T S V C T R A C
31
A V S G+I S T C P++ C T R A C
14
A V S G Y I S S N T C P S T A C T R A C
33
41.9%
NZ_CP016767.1 and 3 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide
Lanthipeptides: BCV50_RS13415_lanthipeptide
8
P I S I A V S G W I S D K T C P T S V C T R A C
31
P ++G+I S T C P T+ C T R A C
3
P A L S V I T G Y I S S N T C P T T A C T R A C
26
41.9%
NZ_CP050134.2 and 3 others:
NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS14310_lanthipeptide NZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide NZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide
Lanthipeptides: HBA49_RS00775_lanthipeptide
3
P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
P+ I P I S I A+ C P T+ C+R C
3
P S T L I P I S I A L--------C P T T R C S R R C
23

#### MIBiG 4.0 matches for MK744_RS03990

24.3%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
7
I P I S I A V S G W I S D K T C P T S V C T R A C
31
+ I V+ +S C P T+ C T C
13
V A I Q A G V A V G V S A A F C P T T K C T S R C
37
19.4%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
22
C P T S V C T R A C
31
C P T+ C T C
17
C P T T K C T S K C
26
allorf_0815941_0816015
Leader:
MTGARTSGGA
Core:
C G L I R S N A K N L T R S
Core with dehydrations:
Cys G L I R Dha N A K N L Dhb R Dha

#### antiSMASH-DB 4.0 matches for allorf_0815941_0816015

100.0%
NC_021362.1 and 11 others:
NZ_AP025342.1 Lanthipeptides: allorf_1476567_1476641_lanthipeptide NZ_AP026714.1 Lanthipeptides: allorf_1207193_1207267_lanthipeptide NZ_CP010524.1 Lanthipeptides: allorf_0181624_0181698_lanthipeptide NZ_CP020352.1 Lanthipeptides: allorf_0187351_0187425_lanthipeptide NZ_CP023168.1 Lanthipeptides: allorf_0187408_0187482_lanthipeptide NZ_CP039297.1 Lanthipeptides: allorf_0098046_0098120_lanthipeptide NZ_CP040672.1 Lanthipeptides: allorf_1092980_1093054_lanthipeptide NZ_CP059318.1 Lanthipeptides: allorf_0097981_0098055_lanthipeptide NZ_CP087137.1 Lanthipeptides: allorf_0097877_0097951_lanthipeptide NZ_CP118744.1 Lanthipeptides: allorf_0187316_0187390_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1660067_1660141_lanthipeptide
Lanthipeptides: allorf_0181474_0181548_lanthipeptide
1
C G L I R S N A K N L T R S
14
C G L I R S N A K N L T R S
1
C G L I R S N A K N L T R S
14
78.6%
NZ_CP051884.1:
Lanthipeptides: allorf_3277830_3277904_lanthipeptide
1
C G L I R S N A K N L T R S
14
C G L I R N A K N L T++
1
C G L I R C N A K N L T K A
14
allorf_0817095_0817172
Leader:
MLVWALPVSLAA
Core:
T Q G I E F S F S S C R Y
Core with dehydrations:
Dhb Q G I E F Dha F Dha Dha Cys R Y

#### antiSMASH-DB 4.0 matches for allorf_0817095_0817172

100.0%
NZ_AP026714.1 and 3 others:
NZ_KZ845958.1 Lanthipeptides: allorf_1543968_1544045_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_000071_000148_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1658910_1658987_lanthipeptide
Lanthipeptides: allorf_1208347_1208424_lanthipeptide
1
T Q G I E F S F S S C R Y
13
T Q G I E F S F S S C R Y
1
T Q G I E F S F S S C R Y
13
allorf_0817463_0817624
Leader:
MGRSHGFGSTTTYSFALFRLAFAAA
Core:
P S L R L N L A C N R N S P V H S T K G T P S L I N E L
Core with dehydrations:
P Dha L R L N L A Cys N R N Dha P V H Dha Dhb K G Dhb P Dha L I N E L

#### antiSMASH-DB 4.0 matches for allorf_0817463_0817624

100.0%
NZ_AP026714.1 and 3 others:
NZ_KZ845958.1 Lanthipeptides: allorf_1543516_1543677_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_000439_000600_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1658458_1658619_lanthipeptide
Lanthipeptides: allorf_1208715_1208876_lanthipeptide
1
P S L R L N L A C N R N S P V H S T K G T P S L I N E L
28
P S L R L N L A C N R N S P V H S T K G T P S L I N E L
1
P S L R L N L A C N R N S P V H S T K G T P S L I N E L
28
25.0%
NZ_CP101397.1:
Lanthipeptides: allorf_6458986_6459099_lanthipeptide
9
C N R N S P V H S T K G T P S L
24
C+R +P S G+P L
1
C D R K A P E W S W M G S P L L
16
21.4%
NZ_AUBN01000022.1:
Lanthipeptides: allorf_16681_16803_lanthipeptide
8
A C N R N S P V H S T K G T P S L I N
26
+C R S +G P L +
1
S C G R G S G S R G I R G W P R L C S
19
with 1 more sequence matches
17.9%
NZ_KZ454939.1:
Lanthipeptides: allorf_0215974_0216129_lanthipeptide
10
N R N S P V H S T
18
N++S P V H++
3
N Q D S P V H T S
11
allorf_0817521_0817646
Leader:
MHARLSRRDGA
Core:
A A K A S L N R A N E Y V V V D P K P C D L P M S R L K V R
Core with dehydrations:
A A K A Dha L N R A N E Y V V V D P K P Cys D L P M Dha R L K V R

#### antiSMASH-DB 4.0 matches for allorf_0817521_0817646

100.0%
NZ_AP026714.1 and 3 others:
NZ_KZ845958.1 Lanthipeptides: allorf_1543494_1543619_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_000497_000622_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1658436_1658561_lanthipeptide
Lanthipeptides: allorf_1208773_1208898_lanthipeptide
1
A A K A S L N R A N E Y V V V D P K P C D L P M S R L K V R
30
A A K A S L N R A N E Y V V V D P K P C D L P M S R L K V R
1
A A K A S L N R A N E Y V V V D P K P C D L P M S R L K V R
30
86.7%
NZ_CP101913.1:
Lanthipeptides: allorf_1817119_1817316_lanthipeptide
2
A K A S L N R A N E Y V V V D P K P C D L P M S R L K V R
30
A K A S L N R A N E Y V V D P K C D L P M S R+K V R
2
A K A S L N R A N E Y A V V D P K L C D L P M S R V K V R
30
20.0%
NZ_CP064879.1:
Lanthipeptides: allorf_8085548_8085745_lanthipeptide
18
K P C D L P M S R L K V
29
P C L P+ L V
2
S P C S L P L Y Y L C V
13
allorf_0817696_0817887
Leader:
MWVAEKFQTNLEIAGS
Core:
L R N S F R A S L G I E N D G G R A L F G L G A H L G L P N S D K L R M P F I Y I R E S D C E
Core with dehydrations:
L R N Dha F R A Dha L G I E N D G G R A L F G L G A H L G L P N Dha D K L R M P F I Y I R E Dha D Cys E

#### antiSMASH-DB 4.0 matches for allorf_0817696_0817887

100.0%
NZ_AP026714.1 and 3 others:
NZ_KZ845958.1 Lanthipeptides: allorf_1543253_1543444_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_000672_000863_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1658195_1658386_lanthipeptide
Lanthipeptides: allorf_1208948_1209139_lanthipeptide
1
L R N S F R A S L G I E N D G G R A L F G L G A H L G L P N S D K L R M P F I Y I R E S D C E
47
L R N S F R A S L G I E N D G G R A L F G L G A H L G L P N S D K L R M P F I Y I R E S D C E
1
L R N S F R A S L G I E N D G G R A L F G L G A H L G L P N S D K L R M P F I Y I R E S D C E
47
57.4%
NZ_CM000721.1:
Lanthipeptides: allorf_5216374_5216547_lanthipeptide
2
R N S F R A S L G I E N D G G R A L F G L G A H L G L P N S D K L R M P F I Y
40
R N S F R A S L ++ G G R A L G L G +G L P N S K L R M P Y
2
R N S F R A S L K C K S L G G R A L I G L G V L I G L P N S V K L R M P M T Y
40
17.0%
NZ_JABWGN010000023.1:
Lanthipeptides: HTZ77_RS41305_lanthipeptide
15
G G R A L F G L G A H L G L P N
30
G G L L G H G P+
1
G G S T L T V L G C H S G A P S
16
with 1 more sequence matches
17.0%
NZ_JABWGO010000017.1:
Lanthipeptides: HT134_RS41585_lanthipeptide
15
G G R A L F G L G A H L G L P N
30
G G L L G H G P+
1
G G S T L T V L G C H S G T P S
16

#### MIBiG 4.0 matches for allorf_0817696_0817887

12.8%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
2
R N S F R A S L G I E N D G G R A L F
20
N+F S + N+G G
3
T N T F S L S N A L G N N G G W C T L
21
allorf_0819132_0819293
Leader:
MSDGQFDWGGRLLKGNGG
Core:
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
Core with dehydrations:
A Q R F P Q N G W K Dha F E E Cys K G R R E L D Cys E Dhb Y K Dha Dha R D E Dha R A

#### antiSMASH-DB 4.0 matches for allorf_0819132_0819293

100.0%
NZ_AP026714.1 and 4 others:
NZ_CP101913.1 Lanthipeptides: allorf_1818804_1818965_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1541847_1542008_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_002108_002269_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1656789_1656950_lanthipeptide
Lanthipeptides: allorf_1210384_1210545_lanthipeptide
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
94.3%
NZ_CM000721.1:
Lanthipeptides: allorf_5214947_5215108_lanthipeptide
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
A Q R F P Q N G W K S F E C K G R E L D C E T Y K S S R D E S R A
1
A Q R F P Q N G W K S F V E C K G I R E L D C E T Y K S S R D E S R A
35
94.3%
NZ_CP039297.1 and 3 others:
NZ_CP040672.1 Lanthipeptides: allorf_1096094_1096255_lanthipeptide NZ_CP059318.1 Lanthipeptides: allorf_0101095_0101256_lanthipeptide NZ_CP087137.1 Lanthipeptides: allorf_0100933_0101094_lanthipeptide
Lanthipeptides: allorf_0101160_0101321_lanthipeptide
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
A Q R F P Q N G W K S F E C K G R E L D C E T Y K S S R D E S R A
1
A Q R F P Q N G W K S F A E C K G T R E L D C E T Y K S S R D E S R A
35
with 1 more sequence matches
88.6%
NC_015215.1:
Lanthipeptides: allorf_0087347_0087508_lanthipeptide
1
A Q R F P Q N G W K S F E E C K G R R E L D C E T Y K S S R D E S R A
35
A Q R F P Q N G W K S F E C K G R E L D C E+Y S S R D E S R A
1
A Q R F P Q N G W K S F A E C K G I R E L D C E S Y N S S R D E S R A
35
allorf_0819396_0819626
Leader:
MAPRCRLVASWGCSRSQGLGCSPIKAARELGSERRETVRSLSVAGVGNLRGA
Core:
V L S T R G P G W T Y R W C T S C S A K G I A G
Core with dehydrations:
V L Dha Dhb R G P G W Dhb Y R W Cys Dhb Dha Cys Dha A K G I A G

#### antiSMASH-DB 4.0 matches for allorf_0819396_0819626

100.0%
NZ_AP026714.1 and 4 others:
NZ_KZ845958.1 Lanthipeptides: allorf_1541514_1541744_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_002372_002602_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_002372_002602_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1656456_1656686_lanthipeptide
Lanthipeptides: allorf_1210648_1210878_lanthipeptide
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
V L S T R G P G W T Y R W C T S C S A K G I A G
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
95.8%
NZ_CM000721.1 and 4 others:
NZ_CP039297.1 Lanthipeptides: allorf_0101424_0101654_lanthipeptide NZ_CP040672.1 Lanthipeptides: allorf_1096358_1096588_lanthipeptide NZ_CP059318.1 Lanthipeptides: allorf_0101359_0101589_lanthipeptide NZ_CP087137.1 Lanthipeptides: allorf_0101197_0101427_lanthipeptide
Lanthipeptides: allorf_5214614_5214844_lanthipeptide
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
V L S T R G P G W T+R W C T S C S A K G I A G
1
V L S T R G P G W T H R W C T S C S A K G I A G
24
47.7%
NZ_CP101913.1:
Lanthipeptides: allorf_1819068_1819298_lanthipeptide
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
V L S T R G P G W T+R W C T S C S A+ I A G
21
V L S T R G P G W T H R W C T S C S A R S I A G
44
with 5 more sequence matches
45.5%
NC_015215.1:
Lanthipeptides: allorf_0087611_0087841_lanthipeptide
3
S T R G P G W T Y R W C T S C S A K G I A G
24
S T R G P W T Y R W C T S C A K G I A G
23
S T R G P E W T Y R W C T S C L A K G I A G
44
32.1%
NZ_CP025546.1 and 5 others:
NZ_CP025546.1 Lanthipeptides: allorf_4260056_4260220_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide
Lanthipeptides: allorf_4260056_4260220_lanthipeptide
3
S T R G P G W T Y R W C T S C S A K G
21
+ R G P W W T C S G
3
T K R G P T W D P L W A T P C S L N G
21
25.0%
NZ_BMVC01000001.1:
Lanthipeptides: IE282_RS02360_lanthipeptide
2
L S T R G P G W T Y R W C T S C S
18
L+ G +R C T+C+
3
L A I S G E E S C F R T C T T C A
19
25.0%
NZ_NNBJ01000009.1:
Lanthipeptides: CG740_RS39730_lanthipeptide
6
G P G W T Y R W C T S C S
18
G G +R C T+C+
6
G E G T C F R T C T T C A
18
17.2%
NZ_JANIOB010000033.1:
Lanthipeptides: NQ113_RS28010_lanthipeptide
6
G P G W T Y R W C T S
16
P G+T R C +
12
N P G F T N R L C P T
22

#### MIBiG 4.0 matches for allorf_0819396_0819626

16.7%
BGC0001155.5 (AGY49587.1):
Thiopeptide: GE2270
13
W C T S C S
18
+C S C S
8
F C C S C S
13
allorf_0820552_0820677
Leader:
MVAQLVEQRIEAPCVGSSTLSHAIYGG
Core:
I A K W L N A T D C K S V P
Core with dehydrations:
I A K W L N A Dhb D Cys K Dha V P

#### antiSMASH-DB 4.0 matches for allorf_0820552_0820677

100.0%
NZ_AP026714.1 and 15 others:
NZ_AP026714.1 Lanthipeptides: allorf_1211804_1211929_lanthipeptide NZ_CP028724.1 Lanthipeptides: allorf_2251561_2251686_lanthipeptide NZ_CP092907.1 Lanthipeptides: allorf_0820552_0820677_lanthipeptide NZ_KB944759.1 Lanthipeptides: allorf_0005263_0005388_lanthipeptide NZ_KZ845892.1 Lanthipeptides: allorf_0004017_0004142_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1540463_1540588_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1540463_1540588_lanthipeptide NZ_LR607361.1 Lanthipeptides: allorf_1048534_1048659_lanthipeptide NZ_LR607361.1 Lanthipeptides: allorf_1048534_1048659_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: allorf_347989_348114_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: allorf_347989_348114_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_003528_003653_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_003528_003653_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1655405_1655530_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1655405_1655530_lanthipeptide
Lanthipeptides: allorf_1211804_1211929_lanthipeptide
1
I A K W L N A T D C K S V P
14
I A K W L N A T D C K S V P
1
I A K W L N A T D C K S V P
14

#### Lanthipeptide(s) for MK744_RS04005

MK744_RS03985
Leader:
MRDEENNETLINNEQVAWFEEVADQSFDDDVFGA
Core:
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
Core with dehydrations:
Cys Dhb Dhb N Dhb F Dha L Dha D Y W G N K G N W Cys Dhb A Dhb H E Cys M G W Cys K

#### antiSMASH-DB 4.0 matches for MK744_RS03985

100.0%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06515_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11265_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03985_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09810_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00085_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07700_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03735_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00120_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07750_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04675_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07990_lanthipeptide
Lanthipeptides: PO853_RS06515_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
93.3%
NZ_BLIS01000009.1 and 7 others:
NZ_BLIS01000009.1 Lanthipeptides: GVO03_RS04820_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_LR134317.1 Lanthipeptides: EL136_RS01685_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_QRWZ01000002.1 Lanthipeptides: DWX18_RS02620_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide NZ_SPGD01000003.1 Lanthipeptides: FGQ50_RS01935_lanthipeptide
Lanthipeptides: GVO03_RS04820_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N K G N W C T T H E C M W C K
1
C T T N T F S L S D Y W G N K G N W C T L T H E C M N W C K
30
93.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06330_lanthipeptide
Lanthipeptides: IE339_RS06330_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N K G W C T A T H E C M W C K
1
C T T N T F S L S D Y W G N K G G W C T A T H E C M S W C K
30
with 105 more sequence matches
Only the first 10 are displayed here.
93.3%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09620_lanthipeptide
Lanthipeptides: CQS04_RS09620_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N G N W C T A T H E C M W C K
1
C T T N T F S L S D Y W G N N G N W C T A T H E C M S W C K
30
86.7%
NZ_FMPI01000012.1 and 1 other:
NZ_FMPI01000012.1 Lanthipeptides: BJR39_RS08305_lanthipeptide
Lanthipeptides: BJR39_RS08305_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N G N W C T A+H E C M W C K
1
C S T N T F S L S D Y W G N N G N W C T A S H E C M S W C K
30
86.7%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23160_lanthipeptide
Lanthipeptides: CN977_RS23160_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C T T N T F S L S D Y W G N G+W C T A T H E C+ W C K
1
C T T N T F S L S D Y W G N D G S W C T A T H E C L S W C K
30
83.3%
NZ_CACZYW010000004.1 and 1 other:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02825_lanthipeptide
Lanthipeptides: HUF10_RS02825_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N G N W C T +H E C M W C K
1
C S T N T F S L S D Y W G N N G N W C T L S H E C M A W C K
30
83.3%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: allorf_0097945_0098112_lanthipeptide
Lanthipeptides: allorf_0097945_0098112_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N+G W C T T H E C M W C K
1
C S T N T F S L S D Y W G N R G Y W C T L T H E C M S W C K
30
83.3%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18440_lanthipeptide
Lanthipeptides: EI692_RS18440_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N K G W C T +H E C M W C K
1
C S T N T F S L S D Y W G N K G G W C T I S H E C M S W C K
30
83.3%
NZ_QGEE01000020.1 and 5 others:
NZ_QGEE01000020.1 Lanthipeptides: DKP74_RS06160_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_QGEF01000018.1 Lanthipeptides: DKP75_RS05595_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide NZ_RPFX01000021.1 Lanthipeptides: EHF19_RS05380_lanthipeptide
Lanthipeptides: DKP74_RS06160_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N+G N W C T +H E C M W C K
1
C S T N T F S L S D Y W G N R G N W C T L S H E C M A W C K
30
80.0%
NZ_CP016767.1 and 11 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13410_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15325_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15325_lanthipeptide NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07920_lanthipeptide NZ_JALAPU010000003.1 Lanthipeptides: MOD17_RS07920_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00580_lanthipeptide NZ_JALATU010000001.1 Lanthipeptides: MOE27_RS00580_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17015_lanthipeptide NZ_JALAUG010000006.1 Lanthipeptides: MOE44_RS17015_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04645_lanthipeptide NZ_JALAVR010000001.1 Lanthipeptides: MOE47_RS04645_lanthipeptide
Lanthipeptides: BCV50_RS13410_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C
29
C T T N T F S L S D Y W G N K G W C T + E C M W C
1
C T T N T F S L S D Y W G N K G G W C T V S K E C M A W C
29
80.0%
NZ_CP051884.1 and 2 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15125_lanthipeptide
Lanthipeptides: HGK68_RS15125_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y W G N G C T T H E C M W C K
1
C S T N T F S L S D Y W G N N G W L C T I T H E C M S W C K
30
80.0%
NZ_FNHR01000005.1 and 1 other:
NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05590_lanthipeptide
Lanthipeptides: BLQ37_RS05590_lanthipeptide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C K
30
C+T N T F S L S D Y G N G N W C T +H E C M W C K
1
C S T N T F S L S D Y M G N N G N W C T I S H E C M A W C K
30

#### MIBiG 4.0 matches for MK744_RS03985

63.3%
BGC0002110.3 (QKV49893.1):
Lanthipeptide: birimositide
1
C T T N T F S L S D Y W G N K G N W C T A T H E C M G W C
29
C T T N T F S L S+ G N G W C T T E C C
1
C T T N T F S L S N A L G N N G G W C T L T K E C Q P N C
29
40.0%
BGC0000517.4 (BAB04173.1):
Lanthipeptide: haloduracin β or haloduracin α
6
F S L S D Y W G N K G N W C T A T H E C M G W C
29
+++S G N K G +C T T E C M C
4
Y N I S C R L G N K G A Y C T L T V E C M P S C
27
12.8%
BGC0001229.4 (SBI_06990):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
19
C T A T H E C M G W C
29
C T + E C C
28
C T L S K E C Q P N C
38
MK744_RS03990
Leader:
MNNDKQNEPNVDLELGKYLEADLISLTDDEVTGG
Core:
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
Core with dehydrations:
G Dhb P Dhb I Dhb I P I Dha I A V Dha G W I Dha D K Dhb Cys P Dhb Dha V Cys Dhb R A Cys

#### antiSMASH-DB 4.0 matches for MK744_RS03990

100.0%
NZ_AP026714.1 and 21 others:
NZ_AP026714.1 Lanthipeptides: PO853_RS06520_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP028724.1 Lanthipeptides: C7I31_RS11270_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_CP092907.1 Lanthipeptides: MK744_RS03990_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KB944759.1 Lanthipeptides: WOA_RS09815_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845892.1 Lanthipeptides: EB42_RS00090_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_KZ845958.1 Lanthipeptides: EB53_RS07695_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607361.1 Lanthipeptides: FN738_RS03740_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LR607378.1 Lanthipeptides: FN751_RS00125_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: AW733_RS07745_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: A5830_RS04680_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: A5824_RS07985_lanthipeptide
Lanthipeptides: PO853_RS06520_lanthipeptide
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
61.3%
NZ_CP051884.1 and 3 others:
NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide NZ_CP051884.1 Lanthipeptides: HGK68_RS15130_lanthipeptide
Lanthipeptides: HGK68_RS15130_lanthipeptide
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
G T P T+ + I V S W I S+ T C P+S C T R A C
1
G T P T V V L S I---V S A W I S N N T C P S S A C T R A C
28
61.3%
NZ_CP061868.1 and 1 other:
NZ_CP061868.1 Lanthipeptides: IE339_RS06335_lanthipeptide
Lanthipeptides: IE339_RS06335_lanthipeptide
2
T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P T I I A V+G+I S T C P T+ C T R A C
2
T P T I V I---T A V T G Y I S T N T C P T T S C T R A C
28
with 77 more sequence matches
Only the first 10 are displayed here.
61.3%
NZ_NUIO01000031.1 and 1 other:
NZ_NUIO01000031.1 Lanthipeptides: CN977_RS23165_lanthipeptide
Lanthipeptides: CN977_RS23165_lanthipeptide
2
T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P T++I ++ A V S G+I S T C P T+ C T R A C
2
T P T V S I A L T-A V S G Y I S S N T C P T T A C T R A C
30
54.8%
NZ_CP027862.1 and 1 other:
NZ_CP027862.1 Lanthipeptides: C3B71_RS16030_lanthipeptide
Lanthipeptides: C3B71_RS16030_lanthipeptide
2
T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P + +A V G+I S T C P T+V C T R A C
2
T P A V A T A A L L A V G G F I S H N T C P T T V C T R A C
31
54.8%
NZ_CP034414.1 and 1 other:
NZ_CP034414.1 Lanthipeptides: EI692_RS18435_lanthipeptide
Lanthipeptides: EI692_RS18435_lanthipeptide
5
I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
+T I S I V S G+I S T C P++ C T R A C
1
V T P A I S I L V S G F I S T N T C P S T A C T R A C
27
54.8%
NZ_PCGR01000003.1 and 1 other:
NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide
Lanthipeptides: CQS04_RS09625_lanthipeptide
1
G T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P T I I A++G+I S +C P T+ C T R A C
1
A T P T I V I---T A I T G Y I S A N S C P T T A C T R A C
28
50.0%
NZ_CACZYW010000004.1 and 3 others:
NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide NZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide
Lanthipeptides: HUF10_RS02820_lanthipeptide
8
P I S I A V S G W I S D K T C P T S V C T R A C
31
P+ +A V S ++S D K T C P T+ C T R A C
9
P V I V A V S A Y V S D K T C P T T A C T R A C
32
48.4%
NZ_KE384533.1 and 2 others:
NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide NZ_KE384533.1 Lanthipeptides: K329_RS31315_lanthipeptide
Lanthipeptides: K329_RS31315_lanthipeptide
2
T P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
T P T I I + V S ++S T C P T+ C T C
1
T P T I V I S V---V S A Y V S T N T C P T T S C T D E C
27
42.4%
NZ_LR134317.1 and 1 other:
NZ_LR134317.1 Lanthipeptides: EL136_RS01690_lanthipeptide
Lanthipeptides: EL136_RS01690_lanthipeptide
7
I P I S I A V S G W I S D K T C P T S V C T R A C
31
+ S+A V+ +I S T C P T+ C T R A C
9
V K A S V A V T A F I S A N T C P T T S C T R A C
33
42.4%
NZ_MIFN01000022.1 and 1 other:
NZ_MIFN01000022.1 Lanthipeptides: BHL26_RS15355_lanthipeptide
Lanthipeptides: BHL26_RS15355_lanthipeptide
12
A V S G W I S D K T C P T S V C T R A C
31
A V S G+I S T C P++ C T R A C
14
A V S G Y I S S N T C P S T A C T R A C
33
41.9%
NZ_CP016767.1 and 3 others:
NZ_CP016767.1 Lanthipeptides: BCV50_RS13415_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide NZ_JALAMZ010000009.1 Lanthipeptides: MOC43_RS15330_lanthipeptide
Lanthipeptides: BCV50_RS13415_lanthipeptide
8
P I S I A V S G W I S D K T C P T S V C T R A C
31
P ++G+I S T C P T+ C T R A C
3
P A L S V I T G Y I S S N T C P T T A C T R A C
26
41.9%
NZ_CP050134.2 and 3 others:
NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS14310_lanthipeptide NZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide NZ_LR134504.1 Lanthipeptides: EL293_RS13085_lanthipeptide
Lanthipeptides: HBA49_RS00775_lanthipeptide
3
P T I T I P I S I A V S G W I S D K T C P T S V C T R A C
31
P+ I P I S I A+ C P T+ C+R C
3
P S T L I P I S I A L--------C P T T R C S R R C
23

#### MIBiG 4.0 matches for MK744_RS03990

24.3%
BGC0001229.4 (SBI_06989):
Lanthipeptide: SBI-06990 A1 or SBI-06989 A2
7
I P I S I A V S G W I S D K T C P T S V C T R A C
31
+ I V+ +S C P T+ C T C
13
V A I Q A G V A V G V S A A F C P T T K C T S R C
37
19.4%
BGC0002110.3 (QKV49894.1):
Lanthipeptide: birimositide
22
C P T S V C T R A C
31
C P T+ C T C
17
C P T T K C T S K C
26
allorf_0819396_0819626
Leader:
MAPRCRLVASWGCSRSQGLGCSPIKAARELGSERRETVRSLSVAGVGNLRGA
Core:
V L S T R G P G W T Y R W C T S C S A K G I A G
Core with dehydrations:
V L Dha Dhb R G P G W Dhb Y R W Cys Dhb Dha Cys Dha A K G I A G

#### antiSMASH-DB 4.0 matches for allorf_0819396_0819626

100.0%
NZ_AP026714.1 and 4 others:
NZ_KZ845958.1 Lanthipeptides: allorf_1541514_1541744_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_002372_002602_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_002372_002602_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1656456_1656686_lanthipeptide
Lanthipeptides: allorf_1210648_1210878_lanthipeptide
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
V L S T R G P G W T Y R W C T S C S A K G I A G
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
95.8%
NZ_CM000721.1 and 4 others:
NZ_CP039297.1 Lanthipeptides: allorf_0101424_0101654_lanthipeptide NZ_CP040672.1 Lanthipeptides: allorf_1096358_1096588_lanthipeptide NZ_CP059318.1 Lanthipeptides: allorf_0101359_0101589_lanthipeptide NZ_CP087137.1 Lanthipeptides: allorf_0101197_0101427_lanthipeptide
Lanthipeptides: allorf_5214614_5214844_lanthipeptide
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
V L S T R G P G W T+R W C T S C S A K G I A G
1
V L S T R G P G W T H R W C T S C S A K G I A G
24
47.7%
NZ_CP101913.1:
Lanthipeptides: allorf_1819068_1819298_lanthipeptide
1
V L S T R G P G W T Y R W C T S C S A K G I A G
24
V L S T R G P G W T+R W C T S C S A+ I A G
21
V L S T R G P G W T H R W C T S C S A R S I A G
44
with 5 more sequence matches
45.5%
NC_015215.1:
Lanthipeptides: allorf_0087611_0087841_lanthipeptide
3
S T R G P G W T Y R W C T S C S A K G I A G
24
S T R G P W T Y R W C T S C A K G I A G
23
S T R G P E W T Y R W C T S C L A K G I A G
44
32.1%
NZ_CP025546.1 and 5 others:
NZ_CP025546.1 Lanthipeptides: allorf_4260056_4260220_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLM01000003.1 Lanthipeptides: allorf_121827_121991_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide NZ_SDLN01000007.1 Lanthipeptides: allorf_135103_135267_lanthipeptide
Lanthipeptides: allorf_4260056_4260220_lanthipeptide
3
S T R G P G W T Y R W C T S C S A K G
21
+ R G P W W T C S G
3
T K R G P T W D P L W A T P C S L N G
21
25.0%
NZ_BMVC01000001.1:
Lanthipeptides: IE282_RS02360_lanthipeptide
2
L S T R G P G W T Y R W C T S C S
18
L+ G +R C T+C+
3
L A I S G E E S C F R T C T T C A
19
25.0%
NZ_NNBJ01000009.1:
Lanthipeptides: CG740_RS39730_lanthipeptide
6
G P G W T Y R W C T S C S
18
G G +R C T+C+
6
G E G T C F R T C T T C A
18
17.2%
NZ_JANIOB010000033.1:
Lanthipeptides: NQ113_RS28010_lanthipeptide
6
G P G W T Y R W C T S
16
P G+T R C +
12
N P G F T N R L C P T
22

#### MIBiG 4.0 matches for allorf_0819396_0819626

16.7%
BGC0001155.5 (AGY49587.1):
Thiopeptide: GE2270
13
W C T S C S
18
+C S C S
8
F C C S C S
13
allorf_0820552_0820677
Leader:
MVAQLVEQRIEAPCVGSSTLSHAIYGG
Core:
I A K W L N A T D C K S V P
Core with dehydrations:
I A K W L N A Dhb D Cys K Dha V P

#### antiSMASH-DB 4.0 matches for allorf_0820552_0820677

100.0%
NZ_AP026714.1 and 15 others:
NZ_AP026714.1 Lanthipeptides: allorf_1211804_1211929_lanthipeptide NZ_CP028724.1 Lanthipeptides: allorf_2251561_2251686_lanthipeptide NZ_CP092907.1 Lanthipeptides: allorf_0820552_0820677_lanthipeptide NZ_KB944759.1 Lanthipeptides: allorf_0005263_0005388_lanthipeptide NZ_KZ845892.1 Lanthipeptides: allorf_0004017_0004142_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1540463_1540588_lanthipeptide NZ_KZ845958.1 Lanthipeptides: allorf_1540463_1540588_lanthipeptide NZ_LR607361.1 Lanthipeptides: allorf_1048534_1048659_lanthipeptide NZ_LR607361.1 Lanthipeptides: allorf_1048534_1048659_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: allorf_347989_348114_lanthipeptide NZ_LSFS01000007.1 Lanthipeptides: allorf_347989_348114_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_003528_003653_lanthipeptide NZ_NGMP01000002.1 Lanthipeptides: allorf_003528_003653_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1655405_1655530_lanthipeptide NZ_NGMV01000001.1 Lanthipeptides: allorf_1655405_1655530_lanthipeptide
Lanthipeptides: allorf_1211804_1211929_lanthipeptide
1
I A K W L N A T D C K S V P
14
I A K W L N A T D C K S V P
1
I A K W L N A T D C K S V P
14

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
PsrA
Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.86 out of 25.88
Confidence: medium
ZuR variant 2
Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 29.31 out of 33.14
Confidence: medium
AbrC3
Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 15.53 out of 18.16
Confidence: strong
ArcA
Description: Repressor of carbon oxidation
Species: Escherichia coli str. K-12 substr. MG1655
Score: 19.10 out of 21.55
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.06 out of 26.06
Confidence: medium
MogR
Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.06 out of 26.06
Confidence: medium
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 24.94 out of 30.25
Confidence: medium
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 25.49 out of 30.25
Confidence: medium
DasR
Description: N-acetylglucosamine dependent repressor
Species: Streptomyces coelicolor
Score: 23.31 out of 27.04
Confidence: medium
PsrA
Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.56 out of 25.88
Confidence: medium
Additional weak hits (11):
HexR
Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 26.37 out of 31.73
Confidence: weak
AfsQ1
Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.58 out of 19.52
Confidence: weak
BldD
Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 18.26 out of 23.43
Confidence: weak
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 20.16 out of 29.72
Confidence: weak
ArgR
Description: Regulator of arginine biosynthesis genes
Species: Streptomyces coelicolor
Score: 17.22 out of 20.01
Confidence: weak
VqsM
Description: Regulator of quorum-sensing signalling systems
Species: Pseudomonas aeruginosa PAO1
Score: 16.58 out of 20.47
Confidence: weak
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 20.81 out of 29.72
Confidence: weak
DosR
Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 19.89 out of 29.51
Confidence: weak
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 16.99 out of 30.12
Confidence: weak
OsdR
Description: Development and stress management regulator
Species: Streptomyces coelicolor
Score: 17.35 out of 30.12
Confidence: weak
DmdR1
Description: Iron(II)-dependent repressor
Species: Streptomyces coelicolor
Score: 24.25 out of 36.53
Confidence: weak
Lanthipeptides
TFBS Finder
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

MK744_RS03985 - Class II
  Cleavage pHMM score: 2.00
  RODEO score: 0
  Monoisotopic mass: 3317.4 Da
  Molecular weight: 3319.7 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3337.7 Da N = 1
    3355.7 Da N = 2
    3373.7 Da N = 3
MK744_RS03990 - Class II
  Cleavage pHMM score: -1.70
  RODEO score: 0
  Monoisotopic mass: 2997.6 Da
  Molecular weight: 2999.5 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3017.5 Da N = 1
    3035.5 Da N = 2
    3053.5 Da N = 3
    3071.6 Da N = 4
    3089.6 Da N = 5
    3107.6 Da N = 6
    3125.6 Da N = 7
allorf_0819396_0819626 - Class II
  Cleavage pHMM score: -5.70
  RODEO score: 0
  Monoisotopic mass: 2448.2 Da
  Molecular weight: 2449.8 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2467.8 Da N = 1
    2485.8 Da N = 2
    2503.8 Da N = 3
    2521.9 Da N = 4
allorf_0820552_0820677 - Class II
  Cleavage pHMM score: -3.90
  RODEO score: 0
  Monoisotopic mass: 1508.8 Da
  Molecular weight: 1509.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1527.8 Da N = 1
MK744_RS03985 - Class II
  Cleavage pHMM score: 2.00
  RODEO score: 0
  Monoisotopic mass: 3317.4 Da
  Molecular weight: 3319.7 Da
  Number of bridges: 4
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3337.7 Da N = 1
    3355.7 Da N = 2
    3373.7 Da N = 3
MK744_RS03990 - Class II
  Cleavage pHMM score: -1.70
  RODEO score: 0
  Monoisotopic mass: 2997.6 Da
  Molecular weight: 2999.5 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3017.5 Da N = 1
    3035.5 Da N = 2
    3053.5 Da N = 3
    3071.6 Da N = 4
    3089.6 Da N = 5
    3107.6 Da N = 6
    3125.6 Da N = 7
allorf_0815941_0816015 - Class II
  Cleavage pHMM score: -3.80
  RODEO score: 0
  Monoisotopic mass: 1477.8 Da
  Molecular weight: 1478.7 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1496.7 Da N = 1
    1514.7 Da N = 2
allorf_0817095_0817172 - Class II
  Cleavage pHMM score: -6.60
  RODEO score: 0
  Monoisotopic mass: 1451.7 Da
  Molecular weight: 1452.6 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1470.6 Da N = 1
    1488.6 Da N = 2
    1506.6 Da N = 3
allorf_0817463_0817624 - Class II
  Cleavage pHMM score: -6.20
  RODEO score: 0
  Monoisotopic mass: 2922.6 Da
  Molecular weight: 2924.3 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2942.3 Da N = 1
    2960.4 Da N = 2
    2978.4 Da N = 3
    2996.4 Da N = 4
    3014.4 Da N = 5
allorf_0817521_0817646 - Class II
  Cleavage pHMM score: -7.20
  RODEO score: 0
  Monoisotopic mass: 3303.8 Da
  Molecular weight: 3305.9 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3323.9 Da N = 1
allorf_0817696_0817887 - Class II
  Cleavage pHMM score: -5.10
  RODEO score: 0
  Monoisotopic mass: 5132.6 Da
  Molecular weight: 5135.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    5153.8 Da N = 1
    5171.8 Da N = 2
    5189.8 Da N = 3
allorf_0819132_0819293 - Class II
  Cleavage pHMM score: -6.00
  RODEO score: 0
  Monoisotopic mass: 4103.0 Da
  Molecular weight: 4105.4 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4123.4 Da N = 1
    4141.5 Da N = 2
    4159.5 Da N = 3
allorf_0819396_0819626 - Class II
  Cleavage pHMM score: -5.70
  RODEO score: 0
  Monoisotopic mass: 2448.2 Da
  Molecular weight: 2449.8 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    2467.8 Da N = 1
    2485.8 Da N = 2
    2503.8 Da N = 3
    2521.9 Da N = 4
allorf_0820552_0820677 - Class II
  Cleavage pHMM score: -3.90
  RODEO score: 0
  Monoisotopic mass: 1508.8 Da
  Molecular weight: 1509.8 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    1527.8 Da N = 1

TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
AbrC3 | Antibiotic production activator
ArcA | Repressor of carbon oxidation
ColR | Phenol-responsive regulator
DasR | N-acetylglucosamine dependent repressor
MogR | Repressor of flagellar motility genes
PsrA | Oleic acid responsive regulator
ZuR variant 2 | Zinc-responsive repressor

NZ_CP092907.1 - Region 4 - cyclic-lactone-autoinducer
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1,566,535 - 1,587,263 nt. (total: 20,729 nt) Show pHMM detection rules used
cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
binding site
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zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
Tailoring
MIBiG comparison
KnownClusterBlast
SubClusterBlast
TFBS Finder
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Tailoring functions
Tailoring enzymes detected in this region
No tailoring functions detected.
Similar gene clusters
Shows areas that are similar to the current region to a reference database.
Mouseover a score cell in the table to get a breakdown of how the score was calculated.The MIBiG database.
Click on an accession to open that entry in the MIBiG database.
Analysis type:

Reference | cyclic-lactone-autoinducer | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.3 |  | 0.41 | ribosomal | enterocin NKR-5-3B | Enterococcus faecium
BGC0001948.3 |  | 0.37 | other (other) | naseseazine C, C3-aryl pyrroloindolines | Streptomyces sp.
BGC0000046.4 |  | 0.35 | PKS | depudecin | Alternaria brassicicola
BGC0002227.3 |  | 0.31 | NRPS | AKML B, AKML D, AKML A, AKML C | Aspergillus luchuensis IFO 4308
BGC0002667.2 |  | 0.30 | ribosomal | estericin A | Clostridium estertheticum
BGC0001246.3 |  | 0.30 | PKS | trans-resorcylide | Sarocladium zeae
BGC0000688.4 |  | 0.29 | terpene | copalyl diphosphate | Diaporthe amygdali
BGC0001954.2 |  | 0.28 | NRPS, PKS | wortmanamide A, wortmanamide B | Talaromyces wortmannii
BGC0001366.5 |  | 0.27 | PKS | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0002058.3 |  | 0.27 | NRPS, PKS | mutanocyclin | Streptococcus mutans B04Sm5

Reference | Aggregated | Similarity score | Type | Compound(s) | Organism
--- | --- | --- | --- | --- | ---
BGC0001291.3 |  | 0.41 | ribosomal | enterocin NKR-5-3B | Enterococcus faecium
BGC0001948.3 |  | 0.37 | other (other) | naseseazine C, C3-aryl pyrroloindolines | Streptomyces sp.
BGC0000046.4 |  | 0.35 | PKS | depudecin | Alternaria brassicicola
BGC0002227.3 |  | 0.31 | NRPS | AKML B, AKML D, AKML A, AKML C | Aspergillus luchuensis IFO 4308
BGC0002667.2 |  | 0.30 | ribosomal | estericin A | Clostridium estertheticum
BGC0001246.3 |  | 0.30 | PKS | trans-resorcylide | Sarocladium zeae
BGC0000688.4 |  | 0.29 | terpene | copalyl diphosphate | Diaporthe amygdali
BGC0001954.2 |  | 0.28 | NRPS, PKS | wortmanamide A, wortmanamide B | Talaromyces wortmannii
BGC0001366.5 |  | 0.27 | PKS | BE-24566B, zunyimycin A | Streptomyces sp. FJS31-2
BGC0002058.3 |  | 0.27 | NRPS, PKS | mutanocyclin | Streptococcus mutans B04Sm5

Similar known clusters from MIBiG 4.0
Shows clusters from the MIBiG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.
Click on an accession to open that entry in the MIBiG database.

No significant matches found.

Similar subclusters
Shows sub-cluster units that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Detailed help and explanations are available here.
Click on reference genes to show details of similarities to genes within the current region.
Double click on a reference drawing to reverse the display of the genes.

No significant matches found.

Transcription Factor Binding Sites
Detailed information for Transcription Factor Binding Site hits, including surrounding genes where applicable.
The strand of the match is shown by an arrow underneath the match.
Detailed documentation is available here.
Binding sites found:
ColR
Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 28.99 out of 30.25
Confidence: strong
IolR
Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.08 out of 23.79
Confidence: medium
CRP
Description: Cyclic AMP receptor protein
Species: Escherichia coli str. K-12 substr. MG1655
Score: 17.55 out of 19.26
Confidence: medium
Additional weak hits (1):
NtrC
Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 20.68 out of 29.72
Confidence: weak
TFBS Finder
TFBS definitions
Shows descriptions for Transcription Factor Binding Site models

Regulator | Description
--- | ---
CRP | Cyclic AMP receptor protein
ColR | Phenol-responsive regulator
IolR | Regulator of the inositol catabolism