LOCUS       NZ_CP092779            24554 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Paenibacillus polymyxa strain ZJ-9 chromosome, complete genome.
ACCESSION   NZ_CP092779
VERSION     NZ_CP092779.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5755887)
  AUTHORS   Zhang,Y. and Gao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2022) School of Chemistry and Chemical
            Engineering, Yancheng Institute of Technology, 211 Jianjun East
            Road, Yancheng, Jiangsu Province 224051, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 265.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022492955.1-RS_2024_03_30
            Annotation Date                   :: 03/30/2024 06:30:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,104
            CDSs (total)                      :: 4,947
            Genes (coding)                    :: 4,884
            CDSs (with protein)               :: 4,884
            Genes (RNA)                       :: 157
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 111
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 34 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 14 of 63
            Pseudo Genes (multiple problems)  :: 12 of 63
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:24:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5076272
            Orig. end                         :: 5100826
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP092779.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jian Gao, 211 Jianjun East
            Road, Yancheng City, Jiangsu Province.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24554
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="21"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24554
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24554
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14554](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14554)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    227..242
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.25"
                     /tool="antismash"
     misc_feature    1794..1807
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.43"
                     /tool="antismash"
     gene            complement(3214..3627)
                     /locus_tag="MJ749_RS22375"
                     /old_locus_tag="MJ749_22375"
     CDS             complement(3214..3627)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822980.1"
                     /locus_tag="MJ749_RS22375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22375"
                     /product="adenylyltransferase/cytidyltransferase family
                     protein"
                     /protein_id="WP_016822980.1"
                     /sec_met_domain="CTP_transf_like (E-value: 6.6e-21,
                     bitscore: 73.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIGYTSGVFDLFHIGHLNLLRNAKSLCDKLIVGVTTDELVSYKY
                     KKAVIPFEERIEIVRNIKFVDTVIPQDSMDKFEVWQKLKYDVMFVGDDWFQNERWDQYE
                     LQFKEVGVKIIYFPYTKSTSSTLLNETLLKLRK"
     gene            complement(3624..5162)
                     /gene="asnB"
                     /locus_tag="MJ749_RS22380"
                     /old_locus_tag="MJ749_22380"
     CDS             complement(3624..5162)
                     /EC_number="6.3.5.4"
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312206.1"
                     /locus_tag="MJ749_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22380"
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="WP_090888644.1"
                     /sec_met_domain="GATase_7 (E-value: 5.5e-39, bitscore:
                     131.1, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 6.5e-58, bitscore:
                     195.2, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGILFSNVAINKEAFLNSLNIMKHRGPTAPLCVYQHENFMLGHN
                     RLSILDLDQRSDQPFFSDDGRYVIIFNGEIYNYKELASTYSIQMRTNSDTELLLKLYIQ
                     YGPQMLNWLNGMFSFIVLDVQHKSFFAARDRMGVKPLYYNKNGEEFIFSSEIAPLLPLV
                     HNVSLDQAAVRQYKKMRCFFNNRTVYNEIKEFPPGYYYENGEFIKYWELDYSEKEPPSD
                     EELEFLIRSAVEYRKIADVEIGSYLSGGLDSTIITALAGVEHTWTVGFEDYNEFEWSEI
                     AATRYNTIHHPILFDPDRFLSLARELVIVKKEPLSVPNEVLLYHMTQQASAKNTVILSG
                     EGADELFFGYDRIFRWASSTTDFDIRAFSDLYTYGSEDDLEIVEDALAPFMKLKSPQKI
                     VAAFFQQAHLRGLLKRLDSASMLNSVEARSPFLDYRLIERLAGLDAQYKMKDGVVKAPL
                     KRIFKDIIPAEIVNRKKVGFPVQLERVLSSEKIEGKTTFDKWFNFNLNTLGEIL"
     gene            complement(5176..6483)
                     /locus_tag="MJ749_RS22385"
                     /old_locus_tag="MJ749_22385"
     CDS             complement(5176..6483)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427437.1"
                     /locus_tag="MJ749_RS22385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22385"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_017427437.1"
                     /transl_table=11
                     /translation="MTQTESVAVEVNNVTKIYKIYDNPNERLKEAIHPFKKKYHSDFKA
                     ISDLSFSIKKGQAIGIIGKNGSGKSTLLKMITGVITPTHGSIKVNGKVAALLELGAGFN
                     PDLTGMENIYLNGTLMGYSKAEMDEKVEDITSFADIGDFINQPVKMYSSGMFARLAFAV
                     AINVDPDILIVDEALSVGDIYFQAKCITKMKELSKKSTVLFVSHSMDTIKSFCDTALLI
                     DKGHMVEIGPVKRVAQIYENIINQEIADMKRVQSLDTFVNSETDKKSTLLLLEEDPAFA
                     KRANEFRSGTGDARFIRADLLVNGEVVNQVPFGEMVTLRLLAQYYKDIDSEGTIGYMVR
                     NHTGVDVFGMNIYNKAKLVPKMQAGGILEVNFNFRNLLSESGKYTISIGLKPKPFEPLY
                     LDSVSIAAVFEVPKPENNYVPGLIFVDNTIDLQVIN"
     gene            complement(6494..7282)
                     /locus_tag="MJ749_RS22390"
                     /old_locus_tag="MJ749_22390"
     CDS             complement(6494..7282)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312208.1"
                     /locus_tag="MJ749_RS22390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22390"
                     /product="ABC transporter permease"
                     /protein_id="WP_240753337.1"
                     /transl_table=11
                     /translation="MNLTQNFSKNLKLLWELSKKDIQSRYLGSFMGVLWAFIHPMVSIL
                     VYWVVFQVGFKNVPIGDTPFILWLLTGMVPWLFFSESLSTATNSIIENNYLVKKIVFRV
                     GLLPMVKILAALFVHVFFIIVLFIMFKIYDVEFTMYNIQILYYLLATILLSLSISYITA
                     TLVVFVKDVGQIVGVFIQLFFWLTPIFWNLNIVEDKYQFFFKLNPVFYIVEGYRDTFIN
                     HKWFWEHPSMTIYFWAIVIIAGTIGIKIFKKMKSHFADVL"
     gene            7433..9892
                     /locus_tag="MJ749_RS22395"
                     /old_locus_tag="MJ749_22395"
     CDS             7433..9892
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013373313.1"
                     /locus_tag="MJ749_RS22395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22395"
                     /product="O-antigen ligase family protein"
                     /protein_id="WP_240753338.1"
                     /sec_met_domain="Wzy_C (E-value: 3.1e-19, bitscore: 67.7,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNPVYGKQAKTSTRDDKRPAMFWVLIVGMILFFAWSPFQAALFN
                     GQMLDFEKPLYWAVIIASILLILAIVSYYKKFKLEEQRDWLAVLVLLLPLSYVLSLTSA
                     ASHYLAMNMVVVQCIYAALFIISIYLLQDRLGNKIIHNLIMTIAYIIVGFGFINWFGQW
                     VLAGKMVGWFTQYVYQYRYTNAVMTDTNGLRLTSVFQYANTYAAFLMAFLFAAVFCLMK
                     SKLWYGKAIHSFMLVPILVSLFLTLSRGGLVMLPVVFVILLLFFKPARQIIWILHCAIA
                     GVASISILAPITNMGLQLNKTYNGGEAAKAWGLLIGVSLAVAVVLWLVEHYLAPKLENA
                     LKGWTSRKLSNLWLPVGSVVVIGLLAFLFMGTGLRSVLPENVQVRLENINFRQHSVLER
                     IAFYQDAAKLIKDHPVIGTGGGGWASLYEQYQDYPYSSRQAHNFFMQYLVEVGIFGFVI
                     LMSFILYIFYKYTRSYIRQNDEERDSHFLYLILALSILLHSLLDFNMSYVFMGILVFMS
                     LGGMAAAMDSKPLKRLSMSASGFRITYSAVIGILSIVVLFSGFRFVQSANAASYGKQIM
                     AVSTSFEEIQNAINKDLALRPTHPDSVLRLAALYKNVYDQTKKDEFYNAAIEVLNTGLK
                     AEPYNKAMYNFKVNLLQAKGENEQAFSILENNIHKFNWDNDWYNMLITQAYTIGNKARE
                     QKDTAKEQKYFQAGLAAYQKVLDGVAHIKTIPPEIELTRTFELTSGIALSTGKIEFMSG
                     KPAEAASILKNGLKDDLSDATNREVARYYITALQQQGQNDEALYKKLIQADPKEKEQIE
                     QLKSLKL"
     gene            complement(10001..11341)
                     /locus_tag="MJ749_RS22400"
                     /old_locus_tag="MJ749_22400"
     CDS             complement(10001..11341)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688744.1"
                     /locus_tag="MJ749_RS22400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22400"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_240753339.1"
                     /sec_met_domain="LANC_like (E-value: 8.2e-65, bitscore:
                     217.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITTGISEDLRQTILEIVQRVARKLIIPEYVNYVCSSKTNQTAFQ
                     EDYKWDNISLASGYPAVSLLFGRLGAVFQEDTFTQYAHQYLVNTREALKLEENISLSLW
                     SGLSGIGFTAYALSDKLRKYYSFIQQINHLIVHYGVALLESSKNNLETGVNFHDYDVIS
                     GWSGIGRYMLLFSDVPEMRDLLEEVLKYLVMLSGERAWKGEVLPSWYIPVHNLPSHEQL
                     RYPEGYFNIGMAHGIPGPLALLSIAWHQNVRVSGHKEAIERYSSWLDHWKQKNDFGWYW
                     PNNISYKEYMNGVIPDETEREAWCYGTPGVARSLWLAGRALENEYLKMSAVDAFKSIYA
                     RPRERWSIYSPTVCHGYSGLIKLTHQMYLDTGDVELREYALGLLLEVVEKFDSEAAFGF
                     CDIVKDTQSVKHLDFVGVLDGVSGIVMTLLDTLESEESVWGSSLLIT"
     gene            complement(11345..14554)
                     /locus_tag="MJ749_RS22405"
                     /old_locus_tag="MJ749_22405"
     CDS             complement(11345..14554)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822973.1"
                     /locus_tag="MJ749_RS22405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22405"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_240753340.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.1e-180,
                     bitscore: 600.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1e-11,
                     bitscore: 43.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.5e-34, bitscore:
                     118.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSAESRNTEMNMFKALEFFLVRIPLLSIEQYEELFIEPWDEGLQ
                     NKLFHILENPIIREALFIASPSLMNSVNQILDNSNLKKADKVIKALAYYMIRLSTRATP
                     YGLFAGVAMGSFNSENKLVLGDLSCNRKVARPDMQWLMDLVKSLERMRNVVEQINVRMN
                     PILYVSGSRMKLPYLNYIDHSDSTDKMKSSSIRISKFVNYAIHCAKEPIPIKLLMNKMQ
                     EEFPTMNQEQLFDFLMKLVEQEFLISNLRPPLSIRNSEMPFEYLKGQLASVTGIDDLKT
                     SIQKIHNHVQQYNQTSVGEGEALYIDISNSMNKMFPCKDPLQIDMETATTSATLSHSIA
                     EEVAEAAEVLWRLSNDVCNPHLETYRSAFIEKYGLHRQIPLLELLDEDMGLGAPPGYEY
                     PVSRRSWEIPATNTDRDKQLACWVGEAIKQGSIEIELTDEKIKKIENVPSGLIPPPSLE
                     MYVTIAASNSNDLEKKNYKLIVNPNSGDPGAGKAFGRFGPILNEAAQGKISSIYELQPD
                     QDPNVVFAELIYLTTNNRHSNVVITNRSCSHQIILGTNNYTDDEAASIPLSDLYVGCTH
                     NSFYLISCSLNKRVIPISTNMLNYYRAPNIYRFLREIQQEGQRNISSFQWGSLSGFPFL
                     PRIRYGNTILSPAMWSLNAGMEAFQRCHTKSEWAHAFERYRKEWSIPRHVYITIDDNRL
                     LMDTTHDFCVSELYDKYQKLSGLASLWLTECGFEWNEVWGESTKGHHIAEFVIPLVRMN
                     GIVPSGIKDLVQPSVMQNPISTSRMNVYFPGDEWLYVKLYGMSEREREFIGNYLRPFCE
                     LAEKQKIIDRYFIVRYRDSDDHVRVRFHGDAAMLCAQLIPAIQSWANKLNQEGLLNQVV
                     YDTYVPEVERYGGESLIQLAEEIFAEDSKLTSEFIFLQYNKKLKIDLEHIAFISVVDML
                     NQWIPSLAKQAEWSQQKDWHNNHTKTFQKNRTWYMSISDVSDQWSSLRAYDYGEFMIER
                     FQPRREKLRQYKESFLQIKKETYGGESLLDIMESFIHMHLNRLMGTDRMKEAKVMSLLS
                     HALYHVNRAQKYTKRMNNKES"
     aSDomain        complement(13796..14059)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MJ749_RS22405_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="5.80E-14"
                     /identifier="RREFam001.1"
                     /label="MJ749_RS22405"
                     /locus_tag="MJ749_RS22405"
                     /protein_end="253"
                     /protein_start="165"
                     /score="43.5"
                     /tool="antismash"
                     /translation="LYVSGSRMKLPYLNYIDHSDSTDKMKSSSIRISKFVNYAIHCAKE
                     PIPIKLLMNKMQEEFPTMNQEQLFDFLMKLVEQEFLISNLRPP"
     CDS             complement(14623..14799)
                     /gene="allorf_5090895_5091071"
                     /locus_tag="allorf_5090895_5091071"
                     /protein_id="allorf_5090895_5091071"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MNSLGLFTLQQEDTLDLDLQISALSVNSSPQCSVTRSVSCAASSC
                     YSWNKYVTCNCCV"
     CDS_motif       complement(14707..14799)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNSLGLFTLQQEDTLDLDLQISALSVNSSPQ"
                     /locus_tag="allorf_5090895_5091071_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14623..14706)
                     /prepeptide="core"
                     /locus_tag="allorf_5090895_5091071_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-2.70"
                     /molecular_weight="2781.2"
                     /monoisotopic_mass="2779.2"
                     /core_sequence="CSVTRSVSCAASSCYSWNKYVTCNCCV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNSLGLFTLQQEDTLDLDLQISALSVNSSPQ"
                     /leader_location="[14706:14799](-)"
                     /alternative_weights="2799.2"
                     /alternative_weights="2817.2"
     misc_feature    complement(14909..14925)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.3"
                     /tool="antismash"
     gene            complement(14912..15790)
                     /gene="galU"
                     /locus_tag="MJ749_RS22410"
                     /old_locus_tag="MJ749_22410"
     CDS             complement(14912..15790)
                     /EC_number="2.7.7.9"
                     /GO_function="GO:0003983 - UTP:glucose-1-phosphate
                     uridylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009225 - nucleotide-sugar metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="galU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312210.1"
                     /locus_tag="MJ749_RS22410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22410"
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="WP_240753341.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 9.9e-09, bitscore:
                     33.9, seeds: 297, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.8e-06,
                     bitscore: 25.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIRKAIIPAAGLGTRFLPATKAMPKEMLPIVDKPTIQYIIEEAV
                     ASGIEDIIIVTGKGKRAIEDHFDYSFELEHNLTSKEKWNLLNEVRKPSEMADIHYIRQK
                     EPKGLGHAIWCARKFIGDEPFAVLLGDDIVESENPCLKQMIDVFDEYQRSIVGVKQVDW
                     NEVHRYGIVEGHALTSKISEAERLVEKPKKEEANSNLAIMGRYILTPDIFDILGQQSAG
                     VGGEIQLTDALSKLGEKNPILAYEFDGNRHDVGEKLGFIETTIHYALQHNEIKDEVLAY
                     MRQVIEDIDKM"
     gene            15978..17009
                     /locus_tag="MJ749_RS22415"
                     /old_locus_tag="MJ749_22415"
     CDS             15978..17009
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688748.1"
                     /locus_tag="MJ749_RS22415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22415"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_102998496.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.4e-25,
                     bitscore: 87.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSIISNPVLTLVIPCYNEEEVLPETISRLTVILEELAESELISK
                     HSKMLFVDDGSRDQTWDIIASYNLKNPFVSGLKLAKNAGHQNALLSGLMEAKETSDCVI
                     SVDADLQDDLNAIREFIIKFKEGNDIVYGVRKSRTTDTFFKRSTAQGFYRLMSKMGVNI
                     VYNHADYRLMSKRVLHELANFKEVNLFLRGLVPLIGYKSTEVYYDRHERFAGESKYPLK
                     KMLAFAFDGITSFSVTPIRLISAVGFGMFGISLLIAAYTLISKFLGTTVWGWSSLMLSI
                     WFIGGLQLVALGLIGEYIGKIYKEVKQRPKYIIETILDSQSTLDTENTKKVNNSEREAV
                     AVQ"
     gene            17023..17460
                     /locus_tag="MJ749_RS22420"
                     /old_locus_tag="MJ749_22420"
     CDS             17023..17460
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016060.4"
                     /locus_tag="MJ749_RS22420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22420"
                     /product="GtrA family protein"
                     /protein_id="WP_338128172.1"
                     /transl_table=11
                     /translation="MTNLTLFQNSFFRFLVVGVLNTICGMSVMFLLFNILETNYWLSTF
                     IGNSVGATVSYFLNKRFTFKNDANHGQTIWKFISIILICYILSYCLSYLISHYLISSLS
                     IKNNEILGNVSILIGNVFYTLINYVGQKFIVFSKKTSVQKV"
     gene            complement(17563..20073)
                     /locus_tag="MJ749_RS22425"
                     /old_locus_tag="MJ749_22425"
     CDS             complement(17563..20073)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822969.1"
                     /locus_tag="MJ749_RS22425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22425"
                     /product="U32 family peptidase"
                     /protein_id="WP_240753342.1"
                     /transl_table=11
                     /translation="MKSAVRREDVELLAPAGDWDCMRAAVANGADAIFFGVEKFNARAR
                     ANNFRMDELPEIMAFLHSYGVKGFLTFNILVFENELEDAKELVDACIDAGVDALIVQDM
                     GLVKMIRDISPDFPIHGSTQMTITSPEAVEFTKPYNMERVVLGRENNLKQIQKIGDQAR
                     LPMEVFVHGALCVSYSGQCLTSEMWGGRSANRGECAQACRLPYDLMVDGEQKPMADVTY
                     LLSPKDLAAIDLMPELIDAGVVSFKIEGRLKTPEYVANVVSKYRKAIDKYFDGDTSKTS
                     KEDIRELQQSFSRGFTHGFLEGTNNKKLVDGTFPKSRGVYLGRVEQILRDGVVCRIDAP
                     LKRGDGIVFDAGDPTQKEEGGRVYDIRRKGVKIEGEAGEGWIVDIVAGRNDVDLRRVHV
                     GDRIWKTNDPALDKRLRQSYETEKPYRVFPVHVRVSGSPGQPLSTWWTDVQKGTTVRVD
                     SELELEIAQKRPMTHELLEEQFGRLGGTVFQLEELDVHLHGDVIVPMRELNSIRRQAVE
                     LLAGERPKPPVYTKRAVEVYGDASAPASSVARGQAELTALCRSLPQVEAALEAGVEFIY
                     ADFEFIKQFPAAVEAVHGAGRRIALVTPRIHMPGENGYHNNILRLQPDAVLVRNPGALY
                     FYMRHRLENPDAHHPQLIGDFSLNIANHKAADLFLDSGCDLVTPSYDLNIQQMVDMLGR
                     TRTDKLEIVIQQHLPMFHTEHCVYCTFMSEGTDYTNCGRPCEDHRASLRDRIGMSHPVR
                     VDEGCRNTVYNAIEQSGAEYLSNFLELGVSRYRVEFLEETPEQVHEVIDLYNRALRGEI
                     SGTQVWKTLKATNQLGVTRGQLVK"
     gene            complement(20506..21027)
                     /locus_tag="MJ749_RS22430"
                     /old_locus_tag="MJ749_22430"
     CDS             complement(20506..21027)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017427431.1"
                     /locus_tag="MJ749_RS22430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22430"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_240753343.1"
                     /transl_table=11
                     /translation="MQLFRAARSVSFGNKKKWKAKYRGNPKIITLKAVDKRNWEECAEL
                     EPSPEQQRFMVSNLYSIAECQFLDGFVSKAIYNDDVLIGFTMFGLDPDDGNYWVYRFMI
                     DERFQGRGHGYHAMLLVIDEIRKASDRTDVIMIGYKPDNELARKLYRKSGFREEGISPW
                     GEMLAKYRFA"
     gene            complement(21317..23230)
                     /locus_tag="MJ749_RS22435"
                     /old_locus_tag="MJ749_22435"
     CDS             complement(21317..23230)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013312214.1"
                     /locus_tag="MJ749_RS22435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22435"
                     /product="stalk domain-containing protein"
                     /protein_id="WP_240753344.1"
                     /transl_table=11
                     /translation="MKHMQRKMMRKLGVGAVALSLLLTALPAVAADQDKNILELRLQSG
                     SNTAIVNGQNANITKPYSKSGALMVPAGVFKKAFNSKIRLAEDNVVKITSGTHVVSLTI
                     GSRTAWVRGHKVTLPAPPEMSSGILMVPLRQVAEGLGGKMEKNGAGIIIRMEAQEEAST
                     VAEESPNIDNDEGKTQIGNSYYDWSMNYPTGLVIGQGGGDESISTFMDENSAYYMEVHT
                     ALQPVPLNADDLLQQLVQAAKETGETVVDRKSFPKAKVPYARVITKDGDGVLWENRQYY
                     DNGRLYVVYFSDAKATNYKDLAQYAGLLNSFKTSFNAQDKSIKDLSTVVGGTREAGNPD
                     YGVSLKIPAGWKMDDQRMQYESNDGSSFRMKVTSAPADGKLENWGQQLQKWLSDSFVST
                     AYEAQKTYPLEVAGVQGLVQEYRYNFGDEWIKEYNVLIQQNGYRYLAEYAVPEKVSKGN
                     DQFNALISSLQIDFQTVANNFGQLEEDDYLADKTKTIKKTSKAYEYTVNIPRYWTAVSD
                     QFELGDIEYQFTGGRFSIKIDNDQSFELTVSQLKDFYDKQAKNYKNLKVEEVKDVTFAG
                     VSAVSFTFHRVEEGIGYTGRQIVLEHNGKTYTVTTTLNDANNTGVQSNALDSTLNSFNF
                     VK"
     gene            complement(23280..24512)
                     /locus_tag="MJ749_RS22440"
                     /old_locus_tag="MJ749_22440"
     CDS             complement(23280..24512)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019688752.1"
                     /locus_tag="MJ749_RS22440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_22440"
                     /product="trypsin-like peptidase domain-containing protein"
                     /protein_id="WP_016822966.1"
                     /transl_table=11
                     /translation="MRKMGKRVAVLALGSALCVSGTAGAASSGTALKAKVINGGVYVNV
                     SDMNKALGTSGAYNSANGTYTLSADRVPQVVKNVSPSVVGIIGRSATGETVAGGDRYNL
                     AHGTGVIIRADGWIVTNAHVIEGLGDAVVVTSDGKSYGIIDSYSDPISDLALIKIKASG
                     LKPATFAASTNSLQVGEQVVAIGTPISFSLRNSATSGVVSGLNRGVNAAYRLIQSDTAI
                     NPGNSGGPLVNLKGEVIGINTMKFSAVGIENMGFSIPADTVKYVINQFFKYGEVRRASL
                     GLGLEESWSAIVGLPTEDPLKVTKVTSASAVQVKIKEGDELYSINGKRVASAIDVNELL
                     KNYQPGQTVSVLMQSDGDIVKRKLVLTQDTGEIYDSIQSGEDLEDSNESGAAVDDGIAP
                     PKEASDSATGK"
ORIGIN
        1 caagttggag ttcgcgatag catcatcatc aatatagagt atgacttcac cctctgctcc
       61 aaataaacca acattacgtg caaaggaaag gccttttaac ggtgcctcca tatatcgcat
      121 gaaggaatca tcaatattat aggttgctct gaactcacga accagatgat gaatctcatc
      181 attctgataa tcattattga caacaatgat ttcatagctc gctttatcca acgactgttc
      241 tatcactgat ttaattgcat tggaaagttt ctcactccgc tggtaagtgc aaataataac
      301 agatagttcc tttttataga cgggttcact ttcaattacc gcctcaatgc gatataagtg
      361 atcgttttta accttggtat ttataagaga gaacagaact tcggtctcct gtgcaaaaaa
      421 gtcatagatg ctatccgtct caccattcat tttatccttt attttcagat cccagggata
      481 gtcagctaca aatgtatctg tggtatgctc tgatttatct ataagcagtg catacataga
      541 cgatgaagca ttagaatcca taaattcaaa attatggact tcgcctgttt taatatataa
      601 atagcaaata ggcgttgcca aattaagacc aataatcgta ttcagttcat ctcttccaac
      661 cacggtatga cctttagcca gaacatattt cttaaactca ctaacttcag cagcatctcc
      721 ctcaataatc caaactaatg gggtcagata aaaatctctt ctaaaatcat caagtaccat
      781 gagtttatat ctgttagatg tgatgccgag ttcttgatct gaagcggtca atgatttatc
      841 atgccagcga taatcatata taggctcatc gaatgtcaca tgtttgagct caaataagga
      901 gttcactctc atccagtaat cataatcttc aagggtatgc ttataactag agtagtcacc
      961 taataagtga gtcaccttgg ccctatacat aaaggccgca ccaatcgtat tgttaggata
     1021 tacatttagc tccaatgcgg atttaggcag cataacatta ccactgaact gtggttcttc
     1081 ataccaacca tggttggaaa ttacttggcc gtccgagtca attaacctca tgttcgcata
     1141 taccatacca atattttcat cacgtttaag atcagcgacc atcttctcca agaaatgttc
     1201 aggaagaatg ttatctgcac tggtccaagt atggtactca cccttagcta gtttaaaacc
     1261 tctggataat gttcttggta ttttacgatt ttcctgatgg actaccctaa tacgatgatc
     1321 tgctttggca tacgcatcaa taatttctgc cgttttatct tttgaaccat cgttaataat
     1381 aatgagttca aaatacttat aagattgctg cagaatacta tcaatagctt tcgatacata
     1441 atcctcaccg ttatatacag gaagaacgat cgatataaga tctttctcaa atgcagtctc
     1501 gaacttatca agttccaggg aaaatgaatt gtctttggct actttataat tataaaattt
     1561 atactcgtac caagttaata actgattgta gtttccttca tctttgcgca gatcaacagg
     1621 atgatcccct gcgttagtcc gtttaagctt atgcgacact ttagatttaa tcttttttag
     1681 taagatcgtg gtgccatagt ttttccatac tctatatccc ttaagaacat atatcatttt
     1741 ggacttgtgt aacatatgtt taagtttatt cgccattttc caccttttag agttataaat
     1801 attatgaagc tccgtggaca gtcttccatt atattcttgc aactcactga actgggtgtt
     1861 cagttcatta tattgaccaa atagttgtct atattgatgg tttaaaatat ccaagttgtt
     1921 tttttcatca ttataatcct gtgtgagttg agcgtactgt tgttctaatt catctttctt
     1981 ttcagacaga gatctaatat ctgctgacat gctgtttatt acattttcct gatgatcacg
     2041 cgtttgaatc aatgtgttaa tctgatccgt atgctcagct atgcgttgtt tttgctgttc
     2101 tatttcttgg ctttgatttt gattatgagt ttgtaattca ttaaattcat tttttagacg
     2161 tgtatgccct gctctataag cctggtctac gtcatcttgt aaaaatctat taattacatc
     2221 catacactta tctatcgtct ctcttccttt gaccggaaac atctctaaag taaatttcct
     2281 tctttgttgt attagttgtt catctaagat tgcattaagt aaagtttgct taatattgtc
     2341 gttatcgctc acaaaaggaa caatgttttg ctgaactatt tgttcttcca aaggtagaat
     2401 cccctcgaac gattctgttt gaggatgctg gaatattaca attggagtat ccgtaaacag
     2461 cgcatcaaat atagccccag agccgtcaga caatattaca tccgcttctt ctattaaatg
     2521 aacaagagaa gccttgtgat caagcacttc aggaacatga gacttaacta gactaacccg
     2581 atcatgctcc aaaaaagaag tgccatggtg caattttacc ttcatattaa aggtatctga
     2641 aatttcttca atatggttca ttacaagctc aatagacgat tcattcccat acgtaggcaa
     2701 ataaagcaaa ttatatttat ccgtttcgcg cttcattctt tgaaatttag catatttaat
     2761 catgcctacg atctcagtct gagtgtaggc tgccagaacc gaggaatcat atagcccatt
     2821 acaaaaaatg aaatcgaaat tccgactcca tgtatctaaa ttccagtttg gtttagccat
     2881 tccatactga tatctgaact tataatcgga cttaacttcc aaataatagg gaaggtaagg
     2941 atagaaggct attttatatg ctttgtcggg tacagcgctt gttagagtca cgtttatacc
     3001 gttattcttc aaataatgat aggtatctaa ggacatgtct ccccaatcat cttcttcaat
     3061 gtgagggaca taaatatcac aaacgatctg ctttttttca cattcctcaa ttaaaggctt
     3121 aatcgtttca tataaaacaa gattgtgaat gacaaaagct atagatctgt tcatattcac
     3181 tgtaaaacct cttcctttca ggcaaaaatc cacttatttt cttaatttca gtaatgtctc
     3241 attcagtaaa gttgatgatg tactcttcgt atagggaaaa tatataattt tcactccaac
     3301 ttccttaaac tgcaactcgt actggtccca acgttcattt tgaaaccaat catcaccaac
     3361 gaacattacg tcatacttta atttttgcca aacctcaaat ttatccatgg agtcctgagg
     3421 aattacagta tcaacaaatt tgatatttct aacaatctca attctttcct caaaaggaat
     3481 gaccgctttt ttgtacttat atgaaaccaa ctcatctgtg gtcacaccca caatgagttt
     3541 gtcacagagt gacttagcat ttctcaacaa attcaaatgt ccaatatgaa ataaatcgaa
     3601 gactccggaa gtatagccga taatcataag atttctccta acgtatttaa attgaagtta
     3661 aaccatttgt cgaatgtcgt cttcccttca attttttcag aagataggac tctttcaagt
     3721 tgaacaggaa aacctacctt ttttctgttt acaatttctg ctgggataat gtctttaaaa
     3781 attctcttga gcggagcctt aacaactcca tccttcatct tatactgagc gtctaaccct
     3841 gcaagccttt caattaatct gtaatccaag aaaggagatc ttgcttctac cgaatttaac
     3901 atcgaggcac tatccagcct tttgagtaac cctcgcaaat gggcttgttg aaagaatgcc
     3961 gctacgattt tttgagggga ctttaacttc ataaaaggtg ccaatgcatc ttctacaatc
     4021 tctaaatcat cttccgatcc ataggtgtag agatcactaa aggctcggat atcaaagtct
     4081 gtggtgctac tagcccatct aaaaatacgg tcatacccaa agaaaagctc atcagcgcct
     4141 tccccactta atatgactgt gttcttagca gatgcttgtt gtgtcatatg atacagcaac
     4201 acttcgttgg gcacagacag aggctctttt tttacaatca ccagctcacg agctaatgat
     4261 aaaaagcgat caggatcaaa taatatcggg tgatgaatag tgttatatct tgttgctgcg
     4321 atttcagacc actcgaactc attataatct tcaaagccaa cagtccaagt atgctctact
     4381 ccagcgagtg cagtaataat cgtgctatcc aagcctccgc taaggtaact tccaatttca
     4441 acatctgcga tcttgcggta ctctactgca gaacgaatta aaaactcaag ttcctcatca
     4501 gaaggcggct ctttctctga ataatcaagt tcccaatatt taataaattc gccattctca
     4561 tagtaatatc ctgggggaaa ctcttttatt tcattataga cagtacgatt attaaaaaaa
     4621 catctcattt ttttatattg tcttacagct gcttgatcta aagaaacgtt gtgaactaat
     4681 gggagcaatg gagcaatttc agaactaaaa atgaactctt caccattctt gttgtaataa
     4741 agcggcttta ctcccatacg atctcgtgct gcaaaaaatg atttgtgctg gacgtctaaa
     4801 acaataaaac tgaacattcc attaagccaa ttcaacattt ggggaccata ttgaatgtaa
     4861 agcttcaata aaagttcagt atctgagttt gttctcattt gaattgaata agtagaagct
     4921 aattctttat aattatagat ttctccatta aatataatca catatcttcc atcatcagaa
     4981 aaaaaaggct gatcacttct ctgatccaga tctaaaatgc ttaatctgtt gtgaccaagc
     5041 ataaaatttt catgctggta tacacaaagc ggggccgtag gcccccgatg cttcattata
     5101 tttaatgaat taagaaatgc ttctttattt atagctacat tagaaaacaa aatcccacac
     5161 attttatcac cagccttaat taataacttg caaatctatt gtattatcta caaatattaa
     5221 acctggtacg taattattct ctggcttagg aacctcaaaa acagctgcta tacttacgct
     5281 atccaaataa agaggctcaa acggcttagg ctttaagcca atagaaatgg tgtatttacc
     5341 actttcagac aaaagattgc ggaaattaaa gttaacctca agaatgcccc ctgcttgcat
     5401 tttcgggact aatttggcct tattgtagat attcatgcca aacacatcta caccagtatg
     5461 gtttctaacc atgtagccaa tggttccctc ggaatcaata tctttataat attgtgccag
     5521 caaacgcaaa gtaaccattt cgccaaaagg gacctggttt accacttctc cattgactaa
     5581 caagtctgcc cttataaaac gggcatctcc cgttccagaa cgaaactcat tggcacgttt
     5641 tgcaaaagca ggatcctctt ctaacaacaa cagcgtactc tttttatccg tttcggaatt
     5701 cacaaatgta tccaaagatt ggacacgctt catatctgca atttcctggt taataatatt
     5761 ttcataaatt tgtgctacgc gcttcactgg accaatttcg accatgtgtc ccttatcaat
     5821 aagcaatgct gtatcacaaa aactcttaat ggtatccatg gaatgagaga caaataaaac
     5881 tgtgctcttt ttagagagct ccttcatttt ggtgatacat ttggcctgaa aataaatatc
     5941 tccaacagac aaggcctcat ccacaatcaa aatgtctgga tcaacattga tggctactgc
     6001 aaaggctaat cgggcaaaca taccgctgga gtacattttg actggttgat taatgaagtc
     6061 cccaatatcc gcaaaggatg taatatcttc taccttctca tccatttctg ctttgctata
     6121 gcccataagc gtaccattta aataaatatt ttccattcca gttaaatccg gattaaaccc
     6181 agcaccgagt tccaacagag ccgcaacttt cccattcacc tttatgcttc catgggtagg
     6241 cgtaattacg cctgtaatca tttttaaaag agtcgatttg cccgaaccat ttttaccgat
     6301 aatgccaatc gcttgccctt ttttaataga aaaggaaagg tcacttatgg ctttgaaatc
     6361 agaatgatat ttctttttaa aaggatgaat agcctctttt aaacgttcat tgggattatc
     6421 atatatttta tatattttag tgacattatt aacttctaca gcaactgatt ctgtttgagt
     6481 catactcttc tcctcacaat acatcagcaa aatgagattt catttttttg aaaattttga
     6541 ttcctatcgt acctgcgatg atcacaatag cccaaaagta gatcgtcatg gatggatgct
     6601 cccagaacca tttgtgatta ataaaggtat cacgatatcc ttcaacaata tagaaaacag
     6661 gattaagttt aaagaaaaac tgatacttat cctcgacaat attcaaattc caaaagattg
     6721 gcgtaagcca gaaaaacaat tgaataaaca ctcctacaat ttgaccaaca tcttttacaa
     6781 aaacaaccaa tgtcgctgtt atgtaggaaa tggacaaaga aagaagaatg gtggccaata
     6841 aataataaag gatttgaatg ttatacatcg taaattcaac atcgtatatt ttgaacataa
     6901 tgaaaagaac gatgataaaa aacacatgga caaaaagagc agccaaaatt tttaccattg
     6961 gtagcaagcc tactcggaaa acaattttct ttaccagata attgttttca ataatactat
     7021 tggttgcagt tgacaagctt tccgaaaaga ataaccacgg caccatgcct gttagtaacc
     7081 aaagtataaa aggagtatca ccaataggta catttttaaa accaacctga aatacgaccc
     7141 aataaacaag tatagatacc ataggatgta taaaagccca gagtaccccc ataaatgaac
     7201 caaggtacct agattgtata tcctttttag acaattccca aagtaacttt aaatttttcg
     7261 aaaagttttg agttaaattc atacgagtgt gtcacgacct taaacatggt ttggtaagtc
     7321 tcttacagta caacaatgta aatatgtggg aagtttattc ttgcgatatg gctctgacag
     7381 ctactatatg ctaaaatgtt gacgtatcta caagaaaagg agattgtaaa ccttgtcgaa
     7441 tccagtatac gggaaacagg ccaaaacgtc gacccgtgac gataaaaggc cggctatgtt
     7501 ttgggtgtta attgttggca tgattctgtt ttttgcttgg tctcccttcc aagctgcact
     7561 ctttaatggg caaatgctcg attttgaaaa accgctctat tgggctgtca tcatcgcctc
     7621 gattctattg atcctggcaa tcgtatctta ttataagaaa ttcaagctgg aagagcaaag
     7681 ggattggctg gctgtattag tactgctgct tcccctgtct tatgtgcttt cactgacttc
     7741 agcagcttca cattacctgg ccatgaatat ggtggtggta cagtgcatct atgccgcttt
     7801 gtttattatc tcaatctatc tactacagga tcgcttaggc aataagatta ttcacaacct
     7861 gattatgact attgcttata tcatcgtagg ctttggcttc attaactggt tcggacagtg
     7921 ggtgcttgcc ggcaagatgg taggctggtt tacccaatat gtgtatcagt atcgctatac
     7981 caatgcagtt atgacagata caaatggtct ccggctgaca tcagtgtttc aatacgcgaa
     8041 tacatatgcg gcctttctaa tggctttcct attcgctgcc gttttttgtc tgatgaaatc
     8101 aaaactatgg tatggcaagg ctatccacag cttcatgttg gtgcctattc tagtctcgct
     8161 attcctgact ttgtcacggg gcggtctggt tatgctacct gtcgtgttcg tgattctttt
     8221 gcttttcttt aaaccagcac gccaaattat atggattttg cattgcgcca ttgctggtgt
     8281 agcgtcaata tctatcttgg cgccgattac aaatatggga ttacaactca ataagactta
     8341 caacggcgga gaggctgcca aggcatgggg attacttatt ggtgtctccc tggctgtagc
     8401 tgtcgtactg tggcttgttg aacattattt ggctccaaag ctggagaatg ctctcaaagg
     8461 atggacctca cgcaagttat ccaatctgtg gctgcctgtc gggtcagttg tggtgattgg
     8521 cttgctggct tttctattca tgggaactgg cctgcgtagc gtactgccgg agaacgtaca
     8581 ggtccggtta gaaaatatca atttccgtca gcatagtgta ctggaacgaa ttgcattcta
     8641 tcaggatgct gccaaattga ttaaagatca tcctgttatt ggcactggcg gcggcggttg
     8701 ggcatcttta tacgaacaat accaggatta tccttatagc agccgtcagg cccataactt
     8761 tttcatgcag tacctagttg aagtaggcat tttcggtttt gtaattttaa tgtcatttat
     8821 cttatatatc ttctataaat atactcgtag ctatattaga caaaatgatg aggagcggga
     8881 ttctcacttt ctgtatctta ttttggcact ctcaatctta cttcacagct tgctggactt
     8941 taatatgagt tacgtgttca tgggcatact ggtattcatg agtctaggcg gcatggccgc
     9001 tgctatggac agcaagcctc ttaaacgctt atccatgagt gcttccggtt ttcggatcac
     9061 gtacagtgca gtcattggta tcctgagtat tgtcgtgcta ttctcaggtt ttcgctttgt
     9121 gcaatcggct aatgctgcct catacggcaa acagatcatg gcggtcagca catcttttga
     9181 ggaaatccaa aatgctatta ataaagatct tgcacttcgt cctacacacc cagattctgt
     9241 tctaagattg gctgcattat ataaaaatgt gtatgatcaa acgaaaaaag atgaatttta
     9301 taacgctgca atagaggtat taaatacggg cttgaaggca gaaccgtata ataaagccat
     9361 gtataacttc aaagttaacc ttttacaagc aaaaggtgag aatgagcaag ctttcagcat
     9421 tttggaaaat aatattcaca aatttaactg ggacaatgat tggtacaata tgttgattac
     9481 ccaggcttac actattggta ataaggcacg tgagcagaag gataccgcca aggaacagaa
     9541 gtatttccaa gcaggtcttg ctgcttatca gaaggttcta gatggggtag ctcatattaa
     9601 gacgattcca cctgaaattg agttgacacg tacctttgaa ttaacctcag gtattgcgct
     9661 cagtactggc aagattgagt ttatgtcagg taagcctgcc gaggctgcaa gcatccttaa
     9721 aaatggcttg aaagacgatc tgagtgatgc tacgaatcgt gaggtcgctc gctattacat
     9781 tactgcccta cagcagcagg gtcaaaacga cgaagcttta tataagaaac tcattcaggc
     9841 tgatccgaag gagaaggagc aaattgagca gttaaagtcc ttaaagctct aggtatacct
     9901 tttaatattg aatgcaaatg cagagataca tcaacaaaaa aaggaacgca gaagtttttc
     9961 acttctagtg ttcctttttt catcctaact tttacttcct ctatgtgatt aacaagctac
    10021 ttccccaaac actttcctcg gattcaaggg tatccaacaa agtcataaca atacctgaaa
    10081 ccccatccaa tacgcctacg aaatccaaat gtttaactga ttgggtatcc tttacaatat
    10141 cacaaaaacc gaacgctgct tcactatcaa acttttcaac gacttctaga agcaaaccta
    10201 gggcatattc acgcagctcg acatctcccg tatccagata catctgatgg gtgagcttta
    10261 ttagtcccga ataaccatga cataccgttg gagaatatat gctccaacgt tcacggggac
    10321 gtgcatatat agatttgaaa gcatccacag cagacatttt taggtattcg ttctccagag
    10381 ccctccctgc taaccataag cttctagcaa cccctggagt tccataacac caggcttcac
    10441 gttctgtttc atcgggaatg actccgttca tatactcttt gtagcttata ttattgggcc
    10501 aataccaccc aaaatcattt ttttgcttcc aatgatctaa ccacgaactg tatcgctcta
    10561 tagcctcctt atggcccgat actctcacat tctgatgcca ggctatcgac agtaaggcca
    10621 acggaccagg aatgccatga gccattccaa tgttaaaata tccttcagga tacctcaact
    10681 gctcgtgtga gggtaaattg tgaacgggga tataccagct tggaagaacc tcacccttcc
    10741 aagctctctc tccacttaac atgacaagat atttaagaac ttcttccagg agatctctca
    10801 tctcaggcac atctgagaac aataacatat atctacctat tccactccat cctgaaatga
    10861 catcgtagtc atgaaaattg acccctgttt ctagattgtt ttttgagctt tccaacaaag
    10921 ctacaccata gtgaacgatt aaatgattaa tctgttgaat aaaactatag tatttacgaa
    10981 gtttgtcaga taacgcataa gccgtgaacc cgatacccga cagcccgctc catagcgata
    11041 aagagatatt ctcctctagc ttaagtgctt ctcttgtatt tacaagatat tgatgcgcat
    11101 attgtgtaaa tgtatcctct tgaaatacag cacccaacct cccgaacaat agactcactg
    11161 ctggatagcc actcgcaaga cttatattat cccatttata atcctcttga aaggctgttt
    11221 gatttgtctt tgatgagcat acataattta catattctgg aattatcaat tttcttgcaa
    11281 ccctttgtac aatctccaga atagtctgac gcaaatcttc cgatattcct gttgtgatca
    11341 tatttcagct ctccttatta ttcattcgct ttgtgtactt ctgagcacgg ttcacatgat
    11401 aaagggcatg gcttaatagt gacattactt tcgcctcttt cattcgatcc gtgcccatca
    11461 atctgttcag gtgcatgtga ataaaacttt ccataatatc caataaagat tcgcccccgt
    11521 atgtttcctt ttttatctga aggaagctct ccttatattg ccttagtttt tccctacgag
    11581 gttgaaagcg ctctatcata aattcaccat aatcatatgc tctcaatgaa ctccattgat
    11641 ctgaaacatc ggatattgac atgtaccatg tacggttttt ttgaaatgtt ttggtgtgat
    11701 tattgtgcca atctttctgt tgagaccatt cagcctgttt agctaatgaa ggtatccatt
    11761 gatttaacat atcaaccaca ctaataaacg caatatgttc caaatcaatc ttcaacttct
    11821 tgttatattg caaaaagatg aattcagaag taagtttgga atcctcggcg aaaatctctt
    11881 cagccagttg aatcaagctt tctccgccgt atctctccac ctctggcacg tatgtatcat
    11941 acacaacttg gttcagcagt ccttcctgat tgagcttgtt cgcccacgat tgaatagcag
    12001 gaattagttg tgcacacaac attgctgcat ctccatgaaa tctcacacgt acatgatcgt
    12061 cagaatctct atatcgaacg ataaaatatc gatcaataat tttttgcttt tctgccaact
    12121 cacaaaatgg tcttaggtag ttcccaataa attctctttc acgctcagac atgccataca
    12181 gcttgacgta aagccattca tcccccggaa agtagacatt catcctacta gtactgatgg
    12241 ggttttgcat aacactaggc tgaacaagat cctttatacc agacgggact atcccattca
    12301 ttctcactaa aggaatgaca aactctgcaa tatggtgtcc tttcgtggac tctccccata
    12361 cttcattcca ttcaaaaccg cattcagtca accaaagaga tgcaagacct gaaagctttt
    12421 gatatttatc atatagttcg gatacacaaa aatcatgtgt agtatccatt aataatctgt
    12481 tatcatcaat ggttatatac acgtgccgcg gaatgctcca ctccttccta tacctttcaa
    12541 atgcatgagc ccattcactt ttggtatgac atctctgaaa agcctccata cctgcattta
    12601 aggaccacat cgctggcgaa agaatagtat taccgtacct tatgcggggc agaaacggaa
    12661 atcctgagag gcttccccat tgaaatgatg aaatatttct ttgcccttcc tgttgaattt
    12721 cacgtaaaaa tcgataaata ttaggcgccc tataataatt cagcatattt gtagatatag
    12781 gaatcactct cttattcaaa gaacatgata ttaaataaaa agagttgtgt gtacaaccta
    12841 catataaatc agataaaggg atagatgccg cttcgtcatc tgtgtaatta ttcgttccaa
    12901 ggataatctg gtgagaacaa gatcggtttg ttataacgac gtttgaatgc ctattattag
    12961 ttgttaaata aataagttcc gcaaaaacca cgtttggatc ctgatcaggt tgtagctcat
    13021 aaatactgga gattttccct tgtgcagctt catttagaat cggaccaaat ctgccaaatg
    13081 ctttgcctgc acctgggtct cctgaattgg gatttacaat caatttataa ttcttctttt
    13141 ccagatcgtt cgaattcgaa gcggcaatgg taacatacat ctctaaagat ggcggaggta
    13201 tgagaccaga tggaacattt tctatttttt tgatcttttc atctgtaagc tcaatctcga
    13261 tactaccttg tttgatcgct tctccaaccc aacatgctaa ttgtttatct ctgtcagtat
    13321 tggtagcagg tatctcccaa cttcgtctgc tcacaggata ttcataacct ggaggagccc
    13381 ctaatcccat atcttcatcc aacagttcta acaagggaat ctgacgatgt aatccatact
    13441 tctcaataaa agcactccga taggtctcaa gatgcggatt gcatacatca ttcgatagtc
    13501 tccataaaac ttcggcagct tcagcaacct cctcagctat actgtggctt aaagttgcac
    13561 ttgttgtagc tgtttccata tcaatttgga gtggatcttt gcaaggaaac attttattca
    13621 tgctgttact tatgtctata tatagtgctt ccccctcacc tacagaggtt tgattatatt
    13681 gttgtacgtg gttatgaatc ttttgaatgg aggtcttgag atcgtctata cctgttacgg
    13741 atgcgagttg cccttttaaa tattcaaacg gcatttcaga gttacgtatg gatagaggcg
    13801 gccttaaatt acttattaaa aactcttgct ctactaactt catcaaaaaa tcaaataact
    13861 gctcttgatt catagtaggg aactcttctt gcatcttatt cattaacaac tttatgggaa
    13921 ttggctcttt cgcacaatga atggcatagt tcacaaactt ggaaatgcgg attgaactgc
    13981 ttttcatttt atcagtggaa tcactatgat ctatatagtt aagataaggt agcttcatac
    14041 gcgatccgga aacatacaag attggattca tacgtacatt gatttgttca acgacattcc
    14101 tcatacgttc caaactcttt acgagatcca ttaaccattg catatctgga cgtgctactt
    14161 ttcgattaca gctcaaatct cctaatacaa gtttgttttc actattaaaa gaacccatag
    14221 caacaccagc aaaaagaccg taaggggtag ctcgtgttga aagcctaatc atataataag
    14281 ctaatgcttt gataacctta tctgctttct ttaaatttga attgtccagt atttgattaa
    14341 cagagttcat taatgaggga ctggcaataa aaagtgcttc acggataatc ggattttcta
    14401 aaatatggaa tagtttgttc tgcaagcctt catcccaagg ttcaataaat aattcttcgt
    14461 actgttcaat agacaacagc ggtattctaa ctaaaaaaaa ttccaaagct ttaaacatat
    14521 tcatttctgt attcctgctc tcagcgctct tcatatctca tgagcctcct taacgtaaaa
    14581 taaccccaga tataggaatc atatctgggg ttgttttgtt aactaaacac agcagttgca
    14641 agtcacatat ttattccaac tatagcaaga agaagcggca caggaaacag agcgagtaac
    14701 actacattga ggtgacgaat taactgataa agcactaatc tgcaagtcca aatcaagggt
    14761 gtcttcttgt tgcaaagtga atagtcctaa agagttcatc tttatacctc cttcgctaaa
    14821 ataagatatt atttggaata ttactctctt attttaagag aagaacttaa aaatccataa
    14881 cttcttttta tcgcatacaa ttacaatttt gttacatttt atcaatatct tcaataacct
    14941 gtctcatata agccagtact tcatccttaa tctcgttatg ctgtagagca taatgaatgg
    15001 ttgtttcaat gaatcccagc ttctcgccaa cgtcatggcg attgccgtca aattcgtagg
    15061 ccagaatagg gttcttttct cccagtttgg acaatgcgtc tgtcagttga atctccccgc
    15121 ctaccccggc ggattgctgc cccaagatat cgaaaatatc aggtgtcaag atataccgtc
    15181 ccatgatcgc taagttggag ttggcttctt ccttcttagg cttttccacc aatcgttccg
    15241 cctcagagat tttggaagta agtgcatggc cttcaacaat cccgtaacga tgtacctcgt
    15301 tccaatcgac ttgttttaca cctacaatag aacgctgata ctcatcgaac acgtcaatca
    15361 tctgcttgag acatggattc tcagactcta cgatgtcatc acccaaaagg acggcaaaag
    15421 gttcatcacc aataaactta cgtgcacacc agatggcatg ccccaagcct ttaggttcct
    15481 tttgacgaat atagtggata tctgccatct ctgatggttt gcgtacttca ttgagcaggt
    15541 tccatttttc ctttgaggtc aaattatgct ccagctcgaa ggagtagtca aaatgatcct
    15601 caattgccct tttgccttta ccagtaacga taatgatatc ttctatacca gatgcaacag
    15661 cttcttcaat aatatattga atggttggtt tgtctacaat gggaagcatc tctttaggca
    15721 tcgctttggt cgcaggaagg aaccgggttc ctaatcccgc agcaggaata attgctttac
    15781 ggattttcat aggtaaaact ccttttcgac aaatcttact aaattattca atagtttgag
    15841 taacgtttgg aaattgctaa tagtttatta tagcacttag tcattgcatt gttatataat
    15901 ttaagtaaac catattatag actaaaaaag atagaaattt gagtaccaga taagccaaaa
    15961 tttgaggaga gagttctttg gattcaataa tcagtaaccc tgttttaacg ttagttattc
    16021 cctgttataa cgaagaagaa gtactgcctg aaaccataag cagacttacg gtgattctgg
    16081 aagagttggc tgagagcgaa ctcatttcta aacatagtaa aatgttgttt gttgatgatg
    16141 gtagccgtga tcaaacatgg gacatcatcg catcatataa tctaaaaaat ccttttgtca
    16201 gtggtctcaa attggcgaaa aatgcgggcc atcagaacgc tctattatct gggttaatgg
    16261 aagccaaaga aacctcagat tgtgtgatat ccgttgacgc tgacctacag gatgatctca
    16321 atgccatccg agaattcata ataaaattca aagaaggtaa tgacatcgtg tatggggtgc
    16381 gaaaaagtag aactaccgat acatttttca aacgttcaac agcccaaggc ttctaccgtc
    16441 tgatgagtaa aatgggcgtt aatatcgtat acaaccatgc agattaccgt ttaatgagca
    16501 aaagggttct ccatgaatta gccaatttta aagaggtaaa tctcttttta cgtggtctag
    16561 ttccgttaat aggttataag tctactgaag tgtattacga tcgacacgaa cgctttgcag
    16621 gtgaatccaa atatccttta aagaaaatgc tcgcttttgc tttcgatgga atcacctcgt
    16681 ttagcgtaac cccgatacgg cttatttcgg ctgtgggttt tggaatgttt ggcataagct
    16741 tattaatagc tgcctatacc cttattagca agttccttgg taccaccgtt tggggctggt
    16801 cttctctaat gttgtccatc tggtttatag gtggtctaca actcgtcgca ctcggactca
    16861 ttggcgagta tatcggtaaa atatataaag aagtaaaaca aagacctaaa tatattattg
    16921 agactatttt agattcccag agcaccttag atactgaaaa cacaaagaaa gtgaataata
    16981 gtgaaaggga agctgtagcg gtccaataac agatgcgaac aggtgactaa tttgacttta
    17041 tttcagaata gttttttccg ttttcttgtc gtaggtgttc taaatacaat atgcggcatg
    17101 tccgtcatgt tcttgctatt taatatttta gagactaact actggttatc gacctttatc
    17161 ggtaattctg taggcgccac tgtaagctat ttcttaaaca aaagatttac cttcaaaaat
    17221 gatgcaaacc atggacagac catttggaag ttcatctcta ttatattgat atgctatata
    17281 ctgtcgtatt gtctcagcta tctaatcagt cactacctga tctcaagttt gagcattaaa
    17341 aataatgaga ttctaggcaa cgtgtctatt ctaatcggga atgttttcta tactttaatt
    17401 aattatgttg gacaaaaatt tattgttttt tctaagaaaa caagcgtcca aaaagtatag
    17461 caataagagg ctcaatggta attttttata taaactagca aatagaaaag ggtatgtgct
    17521 gtcaaagcac ataccctttt cgctttttct atagcagcct tgttacttca ccagttgccc
    17581 acgtgtaacc cctagctgat tcgtcgcttt cagcgtcttc catacttgtg ttccgctgat
    17641 ttcaccgcgc aaagcacggt tatagagatc aataacctca tgaacttgct ctggtgtctc
    17701 ctccaaaaat tccacgcggt aacgggacac gcctagttct aggaagttag acaggtattc
    17761 cgcgcctgat tgctcaatcg cgttgtacac cgtattacgg catccttcgt ccacacgaac
    17821 cgggtgagac atcccaatac gatcacgcag ggatgcgcga tgatcctcac atggacgacc
    17881 acagttggtg tagtctgtgc cttcactcat aaaagtacaa tacacgcagt gttcggtatg
    17941 gaacatcggt aaatgctgct ggatgacgat ctccagcttg tcggtacgtg tacgtcccag
    18001 catatcgacc atctgttgga tgttcaaatc atatgacggt gtcaccaggt cgcagccgga
    18061 atccaggaac aggtcagccg ctttatggtt ggcgatattc agcgagaagt cgccaatcaa
    18121 ttgcggatga tgtgcatccg ggttctccaa gcggtgacgc atgtaaaaat acaatgctcc
    18181 cggattgcgt accagcacag catccggttg caggcgcagg atattgttgt gatatccgtt
    18241 ttcgcctggc atgtgaatac gcggagtcac cagggcaatt cggcgcccag cgccgtgcac
    18301 agcctctacg gctgccggga attgcttgat gaactcgaag tcggcgtaga tgaactccac
    18361 gccggcctca agcgcagcct ccacctgagg gaggctgcgg cacagcgcgg tcagctctgc
    18421 ctgaccgcgt gccacagacg atgccggagc cgaggcatcg ccatacacct ctaccgcccg
    18481 tttcgtgtat acgggtggtt tggggcgctc gcctgcgagc agttccaccg cctgacggcg
    18541 gatgctgttc agctcgcgca tgggcacgat gacgtctcca tgcagatgga cgtccagctc
    18601 ttccagctgg aacactgttc cgcccagtct gccgaattgc tcttcgagca gttcgtgcgt
    18661 catcggacgc ttctgggcaa tttcaagctc cagctcggag tccacgcgaa ccgttgtgcc
    18721 cttctgcacg tcggtccacc atgtcgacag cggctgtcct ggggagccgc tgacccgcac
    18781 atgtaccggg aaaactcggt acggcttttc ggtttcgtac gactggcgca gacgcttgtc
    18841 cagcgccggg tcgttggtct tccaaatacg gtcgcctacg tgcacacggc gcagatccac
    18901 atcattgcgt cctgctacga tgtcaacgat ccagccttct ccggcttcgc cttcaatctt
    18961 cacacccttg cggcggatat cgtatacgcg tccgccttct tctttttgcg taggatctcc
    19021 tgcatcaaat acaataccat cgccacgctt gagcggggca tcgatgcggc atactacccc
    19081 atcacgtagg atttgttcca ctcggcccag gtacacgccc cggcttttcg ggaacgtacc
    19141 gtccaccagc tttttgttat tcgttccttc cagaaaaccg tgcgtaaagc cgcgtgaaaa
    19201 gctctgctgc agctcgcgga tatcttcttt gctcgtcttg gacgtatcgc catcaaaata
    19261 cttgtcaatg gccttgcgat atttgctaac cacattcgct acatactcag gcgttttcag
    19321 tcgcccttca attttaaagg aaaccacccc ggcatcaatc agttctggca tcaaatcaat
    19381 ggccgccaaa tccttggggg atagcaggta tgtcacatcg gccatcggct tttgctctcc
    19441 atccaccatc aaatcgtaag gcaaacggca tgcctgtgca cactcaccac ggtttgcaga
    19501 gcgtccgccc cacatttctg aagtcaggca ttggcctgaa taagatacgc ataacgctcc
    19561 atgcacgaat acttccatcg gaagccttgc ttgatcgcca attttttgaa tctgttttag
    19621 attattttca cgacccagca caacccgttc catgttgtac ggctttgtaa attctacagc
    19681 ctccggcgag gtgatcgtca tttgggtaga accatggatc gggaaatccg gtgaaatgtc
    19741 gcggatcatt ttcaccaaac ccatatcctg aacaattagg gcatcgactc cggcatcaat
    19801 acaggcatca accagctctt tagcgtcctc cagctcgttt tcaaatacca gtatattgaa
    19861 tgtcaaaaag cccttaaccc cgtagctatg caaaaaagcc ataatctcgg gcagttcatc
    19921 catgcgaaaa ttattcgccc gtgctcgtgc gttgaatttt tccaccccaa aaaagatcgc
    19981 atcggctccg tttgctaccg ccgcacgcat acaatcccag tcacctgctg gtgccagaag
    20041 ctcgacatct tctcttcgta ctgctgattt cattattgcc ctccctatat gctgaaaacg
    20101 aatgacccct cattgaatct cgttgttttc agggcagcta tgctgcttac ttggtcatct
    20161 caagaacgtt ccatccactc attccaaagc tggttatgtt cagtcagggg aatggaaact
    20221 tactaagaat catattatta agtcctatct gtctctatca tcttgtccga tcattcacac
    20281 gctgaaccat cggtcctccg catgaatcgc atccaactca aaaaatccgc atcacaaaca
    20341 tctgcggcag aaattattct tatcttgtaa ctaatctagt gtaccagact gcgccccaag
    20401 cttctacact ttccaagcga ttccttaaaa atataatact aaaagcacaa aaacacctcc
    20461 aatccgggtt agcggtgctt tggaggtgcg tcatcatatc attaactagg caaacctata
    20521 cttcgcaagc atttctcccc agggtgatat tccttcctcc ctgaaaccag attttctgta
    20581 tagctttcta gctagttcat tgtctggttt atatccaatc atgataacat cagtcctatc
    20641 actggctttc ctgatttcgt cgataaccag caacattgca tggtaaccat gacctcgacc
    20701 ttgaaatctt tcgtcaatca taaatcggta aacccagtag tttccgtcat ccgggtctaa
    20761 accaaacatc gtaaagccaa tcaatacgtc atcattataa attgctttag atacaaatcc
    20821 atctaaaaac tgacattcgg caattgagta aaggttagat accataaatc tttgttgttc
    20881 aggactcggt tcaagttcag cacattcttc ccaattcctt ttgtcgactg cctttagcgt
    20941 aattattttc ggattccccc tatacttcgc cttccatttt ttcttattac caaagcttac
    21001 tgaccttgcc gcacgaaaca gctgcatgtt aaagctaggt cgtattatag caaaaaggca
    21061 gaataagcct cgtaaaagta gcagccttcg cacttccctg cttacttcac tctttaaaag
    21121 attagggata tttggcggtg gccagcaaag cgggccattt gaatccgaag aagcgcgagc
    21181 gttcgccttt gacctgggat tcttactatt caatccttac acaatccaag aatcccgggt
    21241 caacagcgat cgtaggatca aatggcacgc gtagcctctt cccactacaa ctcactgatc
    21301 ttttacccac accttcttac ttcacaaaat taaacgaatt cagtgtcgaa tccagtgcgt
    21361 tggactgtac acccgtgttg tttgcatcgt ttaatgtcgt tgttacggta tatgttttac
    21421 cgttatgctc cagaacgatt tggcgacctg tataaccgat gccttcctcc acacggtgga
    21481 atgtaaagga cactgccgac acaccagcaa atgttacatc cttaacttcc tccactttaa
    21541 ggtttttata gttcttggct tgcttatcat agaagtcctt aagctgggat accgtcaatt
    21601 caaaggattg gtcgttgtcg attttgatag aaaaacgccc tccggtaaat tgatactcta
    21661 tatcgcccaa ttcaaattga tcgctaaccg cagtccaata ccgcgggata ttcactgtat
    21721 actcatatgc tttagacgtc tttttgatcg ttttcgtttt gtccgccagg tagtcatcct
    21781 cttccaattg tccaaagtta ttcgctactg tttgaaaatc gatttgaagc gaagaaatga
    21841 gcgcgttgaa ctggtcgttt cccttgctta ctttttcagg cactgcgtat tcagccaggt
    21901 agcgatatcc attttgctga attagcacat tgtactcctt gatccattca tccccaaaat
    21961 tatagcggta ctcctgcact aatccctgaa cgcctgcaac ctccagcgga tacgtctttt
    22021 gtgcctcata agcagtagac acaaatgaat cgctcagcca tttttgcagc tgctggcccc
    22081 agttctccaa ttttccatct gctggagcag aggtgacttt catgcggaag cttgatccgt
    22141 cattgctttc atactgcatt cgttggtcgt ccattttcca gcctgcaggt attttgagtg
    22201 acacaccgta gtctggattc ccagcctctc gtgtgcctcc tacaacagtg gacaagtctt
    22261 taatactttt atcctgtgca ttaaaagagg ttttaaagga gttcaacagt ccagcatact
    22321 gggccagatc tttatagttc gttgctttag catcggaaaa ataaacgaca tacagtcgtc
    22381 cgttgtcata gtactgacga ttttcccaca gtacgccgtc cccatccttc gtaataacac
    22441 gagcataagg cactttcgct ttcgggaagg attttcggtc cactacagtt tctcccgttt
    22501 ccttggctgc ctgcaccaat tgttgcaaca aatcgtctgc attcagtgga accggctgta
    22561 atgctgtgtg tacttccata tagtatgcac tgttctcgtc cataaatgtg gaaatactct
    22621 catctccacc cccctgaccg ataacgagtc ctgttggata gttcatggac caatcgtagt
    22681 aactattccc gatctgcgtc ttgccctcat cattatcaat gttcggtgat tcttctgcta
    22741 ccgtgctcgc ctcttcttgg gcttccatcc gaatgatgat tcctgcacca ttcttctcca
    22801 tcttaccgcc cagtccttct gctacttgac gcaaaggcac catgaggatt cctgacgaca
    22861 tttccggtgg agccggaagt gtcaccttgt gtcctctcac ccaggctgta cgactaccaa
    22921 ttgtcagcga tacaacgtga gtgccgctgg tgatcttaac cacattatct tcagctaggc
    22981 gaattttgct gttaaatgcc tttttaaaca caccagccgg aaccatcagt gctccacttt
    23041 tggaataggg tttcgtaata ttcgcatttt ggccgttcac gatggctgta ttgctgccac
    23101 tttgcagacg caattccaat atgtttttat cttgatctgc tgcaactgct ggtaaagcgg
    23161 taagcagaag ggacaatgcg acagcgccga cccccagctt acgcatcatt tttctttgca
    23221 tatgcttcac agtaaatctc cctttagctt tattttatag attgatgagc cgttatcgtt
    23281 cactttcccg tagctgaatc tgacgcttcc ttcggaggcg ctataccgtc atctacagca
    23341 gctcctgatt cattcgagtc ttcaagatct tctccagact gaatggaatc ataaatttca
    23401 ccagtatcct gtgtcagtac cagcttgcgc ttcacaatat caccgtccga ctgcataagt
    23461 acactcaccg tttggcccgg ttgatagttt ttaagcagct cattgacatc aatggcggaa
    23521 gctacacgct tgccgttaat actatacaac tcatcgcctt ccttgatttt aacctgtacg
    23581 gcactggctg aggtgacttt agtgactttc aaagggtcct cggtaggcaa ccccacgata
    23641 gccgaccagc tctcttcaag ccctagacca agactagcac gtcgaacctc accatatttg
    23701 aaaaattgat tgatgacata tttcactgta tccgccggaa tcgaaaagcc catattttca
    23761 attccgaccg ctgagaactt cattgtattg atcccgataa cctcgccctt gagattgacc
    23821 agcggaccac cgctgttacc agggttgatc gcggtatcac tttgaatgag acgatacgca
    23881 gcgttgacac cacggttcag cccgctaaca acacctgagg ttgccgagtt acgaagtgaa
    23941 aaggagatcg gcgtaccaat agctactacc tgctcgccta cctgtaaact attcgtagaa
    24001 gctgcaaagg tagcaggttt aagaccgctt gccttaattt taatcaacgc caagtcactg
    24061 atcggatcgc tgtagctgtc gatgattccg taagattttc cgtccgaggt tacaactacg
    24121 gcatcaccta atccttcgat aacatgcgca ttcgtaacaa tccatccatc tgcccgaatg
    24181 atgacacccg tgccgtgagc caggttgtat cggtctcccc ctgctacggt ctctcctgtc
    24241 gcagaacggc caatgatgcc gactaccgaa ggagatacat ttttaacgac ctgcggcaca
    24301 cgatcggccg ataacgtata tgtaccattt gcgctgttat acgcgccgct ggttcctaat
    24361 gctttattca tatcacttac gttaacatag accccgccat taatgacctt ggcctttaac
    24421 gcagttccac tgctggctgc acctgccgtt ccagaaacac atagagcgct gcccaaagcc
    24481 agcacagcca cccttttccc catcttacgc atatactcac catttcctct ctaacatgac
    24541 cctgttctat cagt
//
