LOCUS       NZ_CP092779            24068 bp    DNA     circular CON 30-MAR-2024
DEFINITION  Paenibacillus polymyxa strain ZJ-9 chromosome, complete genome.
ACCESSION   NZ_CP092779
VERSION     NZ_CP092779.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus polymyxa
  ORGANISM  Paenibacillus polymyxa
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5755887)
  AUTHORS   Zhang,Y. and Gao,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (28-FEB-2022) School of Chemistry and Chemical
            Engineering, Yancheng Institute of Technology, 211 Jianjun East
            Road, Yancheng, Jiangsu Province 224051, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 265.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022492955.1-RS_2024_03_30
            Annotation Date                   :: 03/30/2024 06:30:46
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,104
            CDSs (total)                      :: 4,947
            Genes (coding)                    :: 4,884
            CDSs (with protein)               :: 4,884
            Genes (RNA)                       :: 157
            rRNAs                             :: 14, 14, 14 (5S, 16S, 23S)
            complete rRNAs                    :: 14, 14, 14 (5S, 16S, 23S)
            tRNAs                             :: 111
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 34 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 14 of 63
            Pseudo Genes (multiple problems)  :: 12 of 63
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:24:45
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1402724
            Orig. end                         :: 1426792
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP092779.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jian Gao, 211 Jianjun East
            Road, Yancheng City, Jiangsu Province.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="5"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24068
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14068](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            242..1162
                     /locus_tag="MJ749_RS05890"
                     /old_locus_tag="MJ749_05890"
     CDS             242..1162
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821230.1"
                     /locus_tag="MJ749_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05890"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_019686420.1"
                     /transl_table=11
                     /translation="MQQATGQVPVIRMEGVSKIISSKAIVDNLTLEVPAGQVFGFLGPN
                     GAGKTTTIRMMVGLISISKGDIHICGDSINTDFEKAVSHVGAIVENPEMYKFLTGYQNL
                     QHFARMSPGVSQERIDEAIRLVGLGNRIHDKVKTYSLGMRQRLGVAQAILHRPKLLVLD
                     EPTNGLDPQGIRELRDYLRQLTRTEGITVFVSSHLLSEMELMCDRVAIIQSGRLVDIKQ
                     LKNTEGEVQTAEIAFEVNDAEQAYTLAGAGRVEGNQLLLHLEREQIAEMNSLLAANGVK
                     VYAIRPVARTLEDQFLEVTGGGSIG"
     gene            1155..1937
                     /locus_tag="MJ749_RS05895"
                     /old_locus_tag="MJ749_05895"
     CDS             1155..1937
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369846.1"
                     /locus_tag="MJ749_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05895"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_016821229.1"
                     /transl_table=11
                     /translation="MADFFKLVHNENLKIYLRVRTWIMLGLLAVITAVIPMLISLVSDQ
                     VSVWDGIALTTLFTFFLNTTFTVIVAADSVAGEFTWGTIKLLLIRPWTRSKILLSKYIS
                     VILFSLLGTIVLVLMVTLSSWLMLSKDAPAGSVPLFSDPISYVTLNFLYSYIALFVTMA
                     FAFMLSAVFRSSALAIGLSLFMMFTKTVYNSIGLFSTDRFEWTKYVLFTHMDLKKYLDM
                     PPGTVSSNLTFSLAVLAAYYVVFIAIAWVVFVKRDVST"
     misc_feature    2111..2127
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.86"
                     /tool="antismash"
     gene            2198..3283
                     /locus_tag="MJ749_RS05900"
                     /old_locus_tag="MJ749_05900"
     CDS             2198..3283
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:1905887 - autoinducer AI-2 transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426473.1"
                     /locus_tag="MJ749_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05900"
                     /product="AI-2E family transporter"
                     /protein_id="WP_016821228.1"
                     /transl_table=11
                     /translation="MLQNNRFFRLTSGIVMILLIIYLGTKVSFIFSPLVSLVSLLVVPL
                     MLSFFLYYLLRPIVDVMERRKIKRSISILLIYLVIGVLLFLFSWGVWPTLRDQVTNLFE
                     NAPKLIKSLVDQLSQWRHNQSLRQVLPPGEDPLSQLSDTLNEAFSTLSDYSVKLVSFVS
                     YFFIVLATFPILLYYMLKEGSKFGPKMLNFFPKKYHKDALEVMEDIDSALSSFIVSRVL
                     INVALGLMMFLGFLIIGLPYALLLAVISIFLNFIPYVGAVAASIPVVIIGFLESPSMAL
                     WSLVVVIVAQQIQDNWLSPIVFGKQLDIHPLTVVILLLVGGDLLGILGIILVIPLYMCG
                     KIVIRKVYHLFLERRVEDIME"
     misc_feature    complement(2245..2260)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.69"
                     /tool="antismash"
     gene            complement(3323..3787)
                     /locus_tag="MJ749_RS05905"
                     /old_locus_tag="MJ749_05905"
     CDS             complement(3323..3787)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369848.1"
                     /locus_tag="MJ749_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05905"
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="WP_045244076.1"
                     /transl_table=11
                     /translation="MFKESKKKLSTPATTDTLLANGTSFEGTIEAEANIRIDGHFQGDI
                     YSTRTVVIGESAVVRSDIIARDVILAGKVFGSITTEGRLTITSTGELYGNTATPTLVIS
                     EGGVLNGTSQMNQTMDAESPAAIDKSEDENQSSFSQDIEDSQASLQPEAG"
     gene            complement(3833..4864)
                     /locus_tag="MJ749_RS05910"
                     /old_locus_tag="MJ749_05910"
     CDS             complement(3833..4864)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426474.1"
                     /locus_tag="MJ749_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05910"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_017426474.1"
                     /transl_table=11
                     /translation="MKKGSLNRRMTLLVIRDAQQPPKQLQCSAAAVILVPTLVIASIST
                     LVIGLQIRSSHIISQMETNLAVQSLQMEVTVADKDAAIGRLRQEVMELTNQATSIRERL
                     QRVTELEQQMQQFIRKHGNSSSASSNKSTITPLSWDASGHTGGELIAVHENTALLARQA
                     MDDFQEIEALLDTVERTVPRSIQQANAVQQNLERQQAAQLLQTRRLALAEQGRPSIWPV
                     GSRRMTSSFGYRSDPFTGKSAFHSGVDIAGQSGDPVYAAGAGTVLEAASSGARGKCIII
                     QHPDGLQSWYMHLSGMQVAPGDRVHKGQTIGLLGSTGRSTGPHLHFQIVKHNQPVDPLL
                     YVQ"
     gene            4987..6417
                     /gene="cls"
                     /locus_tag="MJ749_RS05915"
                     /old_locus_tag="MJ749_05915"
     CDS             4987..6417
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686424.1"
                     /locus_tag="MJ749_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05915"
                     /product="cardiolipin synthase"
                     /protein_id="WP_222821897.1"
                     /transl_table=11
                     /translation="MLWLLLVLIIFIFQTGTILLFEFRKPSKAVAWLFILFCFPLIGFV
                     VYYFVAQDYQKRKVVRKAGSQLFREFREHLWAQTKVIENVEQMHNPHFKHQERLFNQLI
                     RMSENPLTGCNRTRVLTNGEETFDAMLKAMEQAQHHIHVEFYIFRADEIGKKFQEVMIR
                     KAREGVKVRFIVDGVGSYHLPYSFIRTCNEAGVEFHYFLPPFFATLDRRINYRNHRKIV
                     VVDGTIGFVGGINVGDDYLGKYPKVGFWRDTHLQIEGDGVYFLQNVFLSDWKLASGERL
                     MDVNLFPPHTCKGDEEVQILSSGPDQVWDTIQELCFGALTVAKKRIWITTPYFIPDPGI
                     YEALKLAAVSGIDVKIIIPYQSDSKLVHLASLSYVQELLEAGVEFYQYRKGFIHAKVVI
                     VDDLLGSVGTANMDMRSFFYNFELTAVLFATSALERLSADFVEDISNSSKIDLNVFRRR
                     PRSQKIAEILTRMLSPLL"
     misc_feature    5007..5020
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.61"
                     /tool="antismash"
     gene            6612..7556
                     /locus_tag="MJ749_RS05920"
                     /old_locus_tag="MJ749_05920"
     CDS             6612..7556
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280287.1"
                     /locus_tag="MJ749_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05920"
                     /product="YitT family protein"
                     /protein_id="WP_013369852.1"
                     /transl_table=11
                     /translation="MSVVSKEVQNLSEITDVTGELTKISKIPANPKNKVKRLLQRAAMI
                     VVGAALMAVGLEIFLVPNGVIDGGVTGISIMASKITGYPLGIFLTLLNLPFLLIGYKQI
                     GKTFALSTLFGIVVMSIGTALLHNVSALTPGEPLLGAIFGGVILGVGVGLVIRSGGSLD
                     GTEIVAILVSEKTPFSVGEIVLFVNIFILGSAGFVFGWPNALYSMIAYYIAMKMIDITI
                     EGLDQSKSVWIISDKYRDIGDALTDRLGRGVTYLEGEGGFTGESKKVIFVVITRLEEAK
                     LKSIVEDWDPHAFIAIGNIHDVKGGRFKKKGIH"
     gene            complement(7625..8527)
                     /gene="ligD"
                     /locus_tag="MJ749_RS05925"
                     /old_locus_tag="MJ749_05925"
     CDS             complement(7625..8527)
                     /EC_number="6.5.1.1"
                     /codon_start=1
                     /gene="ligD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369853.1"
                     /locus_tag="MJ749_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05925"
                     /product="non-homologous end-joining DNA ligase"
                     /protein_id="WP_016821225.1"
                     /transl_table=11
                     /translation="MGRAVKGTITIEGHEIAITNPDKPLWPEAGVTKALYLRKLAVLAP
                     YLLKYCHQRLLTVIRWPHGIHGDFFYQKNAPHPRPDYIETALHDGIEYIVLGKLPQLLW
                     LGNQAALEFHPSLHRTGSQLPCEWMIDLDPSREVEPRIMEAASIVGEVLASLGLDSVPK
                     TSGATGVQIIVPIRTGITFDELRSIGLLVGQFVTEKHPHLFTLERLKKDRGTAIYFDYL
                     QHYQGKTLAAPYTPRARPGATVSTPLTWEEVRQDVSPLDYHLLNIEERLNQVGDLIDKV
                     PPQPVEDLLKHMRSKTHPT"
     misc_feature    complement(8676..8689)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 21.22"
                     /tool="antismash"
     misc_feature    complement(8676..8692)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.89"
                     /tool="antismash"
     gene            8740..10026
                     /locus_tag="MJ749_RS05930"
                     /old_locus_tag="MJ749_05930"
     CDS             8740..10026
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_3: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426477.1"
                     /locus_tag="MJ749_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05930"
                     /product="sulfotransferase"
                     /protein_id="WP_039276897.1"
                     /transl_table=11
                     /translation="MIEKQGGKLVFLLSVPRSGSSLLTAILQNHSRLFATQEMWFLLSL
                     YALPQSHARPYGGTGILRQFFKGMVPPHVLEQAARSYALEIYNGLLQGTTADMLIDKSP
                     RYYTVLEFVDRLFPAARRVWLIRNPLSIVASFKKVNQLRNGNFHLLKELGSPHFNMKMT
                     DITVGLFRYAHYFATPHPLAYPLMYEQLVANPRMEIEKLCHFLEIHYEPGMERYGNFAD
                     TPQSNLFYSMGAGDPFVMEHEQAHQNSVHSWQHLLSTMEVELYCRSIGARLFRQLGYGE
                     ALEQAEQMTGVRFEDDPDVELLSRRTHQFLQQSGFEWKTAYRMLEEQDADNKGFMTNAT
                     CHAAPHNPARMDMAQIVSDRRIQSLENRLAHSFEERNRLIAQLQSYQRPSQGFRSHLLA
                     RKFGRWASEVLSSIGKEKGGERECNCRNL"
     gene            10001..11926
                     /locus_tag="MJ749_RS05935"
                     /old_locus_tag="MJ749_05935"
     CDS             10001..11926
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369855.1"
                     /locus_tag="MJ749_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05935"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_039276899.1"
                     /sec_met_domain="GATase_7 (E-value: 1.2e-19, bitscore:
                     68.6, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 5.5e-25, bitscore:
                     86.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAIAGIYRFGHESVYAEEGEKMMQTLQKYPADRVCAWCEGSIFL
                     GCHAQHVTPESVHERLPFYDELRDLAITADAIIDNRSELFERLAVEQGRRIDITDSELI
                     LLAYDKWGVDAAGYLIGDFAFVIWDAKKHRLYGARDMTGNRTLYTYQHDGGFAFSTVVA
                     PLLVLSSLRKELHEPWLAEFLSIRAMQESVDIGTTAYKHINQLPPAHWFTMEEGKQSLC
                     KYACLDEVEPLRLNTGGEYIEAFREVFSQAVTARLRTHRAVGAALSGGLDSGAVASFAA
                     PALHLQHKPLHAYSYVPVQDFTDWTPPTLLANERSYIQSTARYVGNIHENYMDFEGKSP
                     FSEIDIWLELMEAPYKYFENSFWIRGFYEKAQEHNVGVLLTGARGNFTVSWGPALDYYA
                     RQFRRLHWLQSWQGVRRYSKLTGSRMSHLLPVMLKKATLLDARTWWGRGKQSPIPSLIH
                     PEFAKRMNVEDIPVLSGTGWRKNADQTRKEKFSNLAIANKNGVMATKLSLRYGLWERDP
                     TGDSRVIRFCLSVPFEQYVQNGRDRALIRKAMRDHLPDDVRLNQRVRGVQPADWLHRML
                     PCWDTFMGELQVMCHDLRAAEYLNMDYIKTAMAKYRHPRPDQASDPNIRLFMHSLIVYR
                     FLCGLN"
     gene            11980..12108
                     /locus_tag="MJ749_RS05940"
                     /old_locus_tag="MJ749_05940"
     CDS             11980..12108
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369856.1"
                     /locus_tag="MJ749_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05940"
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_013369856.1"
                     /transl_table=11
                     /translation="MSKKEWQEPTIEVLDINQTMAGKGWKQIDWVSDHDADLYNPS"
     gene            12237..13292
                     /locus_tag="MJ749_RS05945"
                     /old_locus_tag="MJ749_05945"
     CDS             12237..13292
                     /EC_number="2.7.1.24"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821222.1"
                     /locus_tag="MJ749_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05945"
                     /product="dephospho-CoA kinase"
                     /protein_id="WP_039276902.1"
                     /transl_table=11
                     /translation="MSPIAHDRSAHNSWVKYTAFGLRIASELTLPELIPAEPGLVEDVV
                     IRQVDLSAWRDQLEQANFVMQGERFMFLIPDTAIYAIRGGKEIEVSMLPRADPDTVRLF
                     VLGTCMGVLLLQKRVLPIHGSAVVIGGRVYAFVGESGTGKSTLAAAFRQAGYQMISDDV
                     IAINVTASAAIVYPAYPQQKLGLESLLQLEALRENKYVRQRKHVLSLTDGNPVRAQYQD
                     LRRISGELNKYAVPAVDEFYNDPLPLGGVFELVSDSPNRESMREGEPVVVTEQPLNKLE
                     CLHTLLQHTYRRAIISRMGLGEWYFDTAARMARKVEGWRLLRDSSFFTASEVVQRVLEL
                     IHKEEKSYGSH"
     gene            13279..13581
                     /locus_tag="MJ749_RS05950"
                     /old_locus_tag="MJ749_05950"
     CDS             13279..13581
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369858.1"
                     /locus_tag="MJ749_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05950"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_016821221.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.2e-24,
                     bitscore: 83.5, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.8e-16, bitscore: 58.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAINPAKDHYRITYGEEVYVSDMDGEKVMMSIHTGKYYNLGFTG
                     GRIWELAESSPSLGDIVTVLTNEYEVDEEQCRQQVHTFVAELEREGLLRLLRELD"
     aSDomain        13327..13560
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MJ749_RS05950_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.30E-26"
                     /identifier="RREFam002.1"
                     /label="MJ749_RS05950"
                     /locus_tag="MJ749_RS05950"
                     /protein_end="94"
                     /protein_start="16"
                     /score="83.5"
                     /tool="antismash"
                     /translation="EEVYVSDMDGEKVMMSIHTGKYYNLGFTGGRIWELAESSPSLGDI
                     VTVLTNEYEVDEEQCRQQVHTFVAELEREGLLR"
     gene            13583..14068
                     /locus_tag="MJ749_RS05955"
                     /old_locus_tag="MJ749_05955"
     CDS             13583..14068
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821220.1"
                     /locus_tag="MJ749_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05955"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_016821220.1"
                     /sec_met_domain="PF13471 (E-value: 8.3e-24, bitscore: 82.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIQRLLLLSPEVGRLLPEAWLELGCARFRQRRSFGDYSGAWGTC
                     MEETSWQCEIGQEKSIRHISQAVDVASRYTPWRSSCLVQAAAAMTLLVRRKLDCTLYLG
                     TAKNAAGQLAAHAWVRSGPIYVTGEREMGAFTVVGIFGRRAGTATNTRTADKGSSLF"
     gene            14126..15652
                     /locus_tag="MJ749_RS05960"
                     /old_locus_tag="MJ749_05960"
     CDS             14126..15652
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426482.1"
                     /locus_tag="MJ749_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05960"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_016821219.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 1.9e-82, bitscore:
                     274.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKSILELANWNEDQELTLLLSLLRKDVNLWQNTMTASQLQEID
                     WSRLLRLTEHHRVIPTVYLQLKTLNHPFIPAELLRNLQAQYHRNTLRMLHLQAEAERLT
                     RLLTAHGIRVLMLKGPALAQQLYGDVSLRTSKDIDLLIAPDDMDEAEHWMKEAGYASKS
                     GEVRVLGSWKWKDHHASFLHPQKRVEVELHWRLHPDGGREPSFDELWGCRQMGKAPAVR
                     ASQMAPATSADSRNVTTSCMYTLGSEHQFLYLSAHGARHGWFRLRWLVDIDRLAVRAVD
                     WGALLPLMRRYGGLPAGGQAWALAAALLGTPIPEPMGPISATRQAHRLALSALAFMQAS
                     VPAPYPVANGADTGRLVQPELLPNVALTESMNTAPSDGGISANGTSGEAVLYAVSSAAG
                     ISKDASSILGDPVNTVNTAVSSLAKPVGAATVASSPAIAGATTTAFTPQPVSRAYLLSL
                     KEPRHRLWYLISRLFPSTRDSVICPLPRQLHFLYIPLRPFLWLKRRFSKH"
     gene            15673..17532
                     /locus_tag="MJ749_RS05965"
                     /old_locus_tag="MJ749_05965"
     CDS             15673..17532
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016821218.1"
                     /locus_tag="MJ749_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05965"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_016821218.1"
                     /transl_table=11
                     /translation="MTHLRLYMTKLYSVNGGALFLNIGCMMIVSLLEGVGIYMLVPMLA
                     AIGVFGGHSEMPFLSDGFDYFLPYIPKSWLLPGMLMFFVMLLTGQAWLQRYQSILNSRI
                     QQRFMRSLRIDVYTSFMKAQWAFYLRQRKSDFSHVMTTELARVSQGTNLLLQLTTAVMF
                     TLIQIALAFWLSPSLTGLVFLSGLVLFVVFRRSIRNAKQLGDRTTELSQIYFAGITDHM
                     NGMKDIKSNLLEAANIHWFRSLTQRMEDNTTQFVRQNATTQFFHRIAAAVFVVSVLFVS
                     LQWLHVTPEKLIVLILIFSRLWPRFALIQASLEYIMSMISAFESVTKVQRECEAFSDPS
                     LIGLTSSENHVPFDSSVNHLSSTSARQPLSLRNGIECSHLDYCYEGAAVSALRHINLLI
                     PARGMTAIVGKSGAGKSTMVDVLMGFLRPTGGQIKIDDHVLDDKLLPLWRQSFGYVSQD
                     PFLFHATVRENLKLADKDASEQQLWEALHFAAADNFVSRLPEGLDTVIGDRGIRLSGGE
                     RQRLVLARAILHHPPVLILDEATSALDGEHEAAIQAALERMKGQMTLIVIAHRLSTIRH
                     ADQIVVLDQGEVIQQGNYHQLVEEERGAFSQLLSYQSTVSAAP"
     gene            complement(17552..18466)
                     /locus_tag="MJ749_RS05970"
                     /old_locus_tag="MJ749_05970"
     CDS             complement(17552..18466)
                     /GO_function="GO:0045027 - DNA end binding [Evidence IEA]"
                     /GO_process="GO:0006303 - double-strand break repair via
                     nonhomologous end joining [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309197.1"
                     /locus_tag="MJ749_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05970"
                     /product="Ku protein"
                     /protein_id="WP_016821217.1"
                     /transl_table=11
                     /translation="MHTVWKGAISFGLVHVPVKMFSATEDKDISMRYIHKECGSPLSYV
                     RKCPVCDKEVEWEEIGKGYEYEKGKFVMFDKEELEQVSGQADKNIVILDFVDLQEIDPI
                     YFQKTYYLSPDQAGSNAYKLLMNAMKDTGKIGIAQISIRSKSSLAAIRVLDECLAVETM
                     FYPDEIRPIAQVPNLPGQEEVKEKELTMAKMLIEQLSTPFDAAKYTDQYRERLLDLIQH
                     KVAGEEVRIAPTQPQTNVVDLMAALQASIEAVKPVVTDPGPAAKKRPARKPAAVTAQQA
                     VAGDAISPAPVKKRRSSTKRKET"
     gene            18675..18914
                     /locus_tag="MJ749_RS05975"
                     /old_locus_tag="MJ749_05975"
     CDS             18675..18914
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369863.1"
                     /locus_tag="MJ749_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05975"
                     /product="hypothetical protein"
                     /protein_id="WP_016821216.1"
                     /transl_table=11
                     /translation="MPRKPYPQQISHRVGQSQIAFRGPAAGEQDALPPEFALSHGTPPP
                     FPVAVAHVDLEAVVSTSPSHSFPSLDVERIIDED"
     misc_feature    18682..18693
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.67"
                     /tool="antismash"
     gene            18966..19145
                     /locus_tag="MJ749_RS05980"
                     /old_locus_tag="MJ749_05980"
     CDS             18966..19145
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013309199.1"
                     /locus_tag="MJ749_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05980"
                     /product="H-type small acid-soluble spore protein"
                     /protein_id="WP_025364276.1"
                     /transl_table=11
                     /translation="MNVERAKAIYDSSETIAVQLDGKPIWIEHVDEANGMATIQIGSRP
                     GNTQTVRVDRLEEQ"
     gene            complement(19275..19931)
                     /locus_tag="MJ749_RS05985"
                     /old_locus_tag="MJ749_05985"
     CDS             complement(19275..19931)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013369865.1"
                     /locus_tag="MJ749_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05985"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_039276907.1"
                     /transl_table=11
                     /translation="MNNRELIIRRIAQEFKDGEVVNLGIGLPTMAVDYIPENVNIMLQA
                     ENGIVGVGPKAAPGKERLDCIDSGGNYVTTVKGACYIDSALSFSIIRGGHVDVTVLGAL
                     EVDEKGNLANWMIPGKKVPGMGGAMDLVVGAKRVIVAMEHVNKNGAPKILKQCKLPLTA
                     VNVVKTIVTEKGVIDVIPGKGLMLKEIAPGLSVEDVQMATEAELMVSPHLKTIAV"
     gene            complement(19924..20592)
                     /locus_tag="MJ749_RS05990"
                     /old_locus_tag="MJ749_05990"
     CDS             complement(19924..20592)
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017426488.1"
                     /locus_tag="MJ749_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05990"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_025364277.1"
                     /transl_table=11
                     /translation="MNKKVNSAEEAVKKIKDGDTVMVGGFMQGGIPEELVRALVDTNSA
                     DNLTIISNDTGTPELSIYRLVKSGRVKRIFASYIGSNPETGRLLMTKEADVQLFPQGTL
                     AEKIRAGGAGLGGILTPVGVGTIVEEGKKKIKIDEREYLLELPLKADVALIRAHKADEA
                     GNLVINGSSRNFNLVMATAAEYVVAQTDEYVKAGEIDPNHINVPGIFVDAIVKVGGDNE
                     "
     gene            complement(20630..21370)
                     /locus_tag="MJ749_RS05995"
                     /old_locus_tag="MJ749_05995"
     CDS             complement(20630..21370)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019686439.1"
                     /locus_tag="MJ749_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_05995"
                     /product="acetoacetate decarboxylase"
                     /protein_id="WP_031463089.1"
                     /transl_table=11
                     /translation="MNQKDVLSLQSMPAASGSYGRPPCRFINREFFIITYESDPAAIRQ
                     AVPEPLQPDGSNTVSYEWIKMPDSSGLGSYEESGIVIPCTYNGEPCNFVAQMYLDNAPA
                     ILGGREIWGFPKKWAKPRLIVEDTETLTGTLHYNNALVAMGTTPFKYNVLDEKETAKAI
                     AKTQVNLKLIPDVDGTPKIAQLVAYNLEDITVKGAWSGPARLSLIPHVNAPVADLPVRA
                     YVGGKHFIADLTLPYGRVLYDYLQ"
     gene            complement(21426..22610)
                     /locus_tag="MJ749_RS06000"
                     /old_locus_tag="MJ749_06000"
     CDS             complement(21426..22610)
                     /EC_number="2.3.1.9"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429859.1"
                     /locus_tag="MJ749_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_06000"
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="WP_039277368.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.8e-05, bitscore:
                     21.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKVAIVSPLRTAVGSFNKALAPLSAPELGATMMTACLQQSKLEP
                     SLIDQIFMGNVLQAGNGQNPARQAALKAGIPIDVPESTINTVCGSGLHAVALAYDSILA
                     EQGNIVLAGGMESMSNAPYLLKNARNGYKLGNGELVDSLVADGLTCPINHYHMGITAEN
                     VAEKYGISRLEQDAFAYESQIKAVEAKNNKVFEEQIVPVMIKNKKETTYFTEDEHIRGN
                     TTKEKLSQLKPAFKENGTVTAGNASGINDGAAAMLVVSEDKCKEHALKPLAYIKGYSLV
                     GVDPAYMGMGPVKAISSLLKKQGMSIDDIDLFEINEAFAAQALAVQKELGVNPEKVNVN
                     GGAIAIGHPVGASGARVLVTLVHEMVRRSSRYGVVSLCIGTGMGIAMLVENALI"
     misc_feature    22927..22941
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     strong, score: 24.83"
                     /tool="antismash"
     misc_feature    23186..23195
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            complement(23273..23803)
                     /locus_tag="MJ749_RS06005"
                     /old_locus_tag="MJ749_06005"
     CDS             complement(23273..23803)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007429259.1"
                     /locus_tag="MJ749_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MJ749_06005"
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_016821206.1"
                     /transl_table=11
                     /translation="MGQTVLLLIDVQQAMFMYDEKLYREQEVVAHLQQLLTEARASGTP
                     VIFVQHTDEADEDFRENSLGWAIADVVRPLPQERIVRKSSWDSFYQTELRDVLQGLGAS
                     QLIIAGMQTEFCLDTTCRSAYSLGYQNNVLVSDAHSTFDSKVLSGEQIVAHHNAVLGNR
                     FARLLTTADVHFS"
     misc_feature    complement(23826..23843)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.23"
                     /tool="antismash"
ORIGIN
        1 attacggtca ctcagcacta caagacccga ttcggtactt ttgatatcgt acagccttgt
       61 tatgtgacgc aggaagatga ggagtggaga gtgctttgga tatacaagga gaaggaacag
      121 acgtgataag gtgctcccaa aggtgtttct gacaggataa atatggtaca atacttccaa
      181 aaccggaaat gtacagtaaa atggatgaca gcttcactcc gggtggaagg agtttcatag
      241 catgcagcaa gcgacagggc aggttcccgt catacggatg gagggtgtga gtaaaatcat
      301 ttcctcaaaa gcgatcgtgg acaatctgac actggaggtt ccggcaggac aggtatttgg
      361 tttcctcgga ccgaacggtg caggaaaaac gaccaccatt cgtatgatgg ttggcctgat
      421 ttcgatcagc aagggtgata ttcatatttg cggagacagc attaataccg atttcgaaaa
      481 ggctgtttcc catgtcggtg cgattgttga gaacccggag atgtacaagt ttttgacagg
      541 ctatcaaaat ttgcagcatt ttgcgcgaat gtctcccggg gtgagccaag agcgtataga
      601 cgaagcgatt cgtctggtgg gactcggaaa ccgaattcat gataaagtca aaacctactc
      661 gctcgggatg cggcagcgac tcggggtagc tcaggcgatt ttacatcgac cgaagctgct
      721 tgtgctggat gagccgacca atggcttgga cccgcagggt attcgtgaac tgcgggatta
      781 tttgcgtcaa ttgacccgta ccgaaggaat taccgtgttt gtatcaagcc atttgttgtc
      841 cgaaatggag ctgatgtgcg atcgcgtggc cattattcag agcgggcgat tggttgatat
      901 taagcagttg aagaatacag agggagaagt gcagacggcg gaaattgctt ttgaagtcaa
      961 tgatgctgag caagcttata cgcttgctgg agcagggcgc gtcgaaggca atcaactact
     1021 gcttcacctg gagcgggaac agattgcaga gatgaacagt ctgctggctg caaatggagt
     1081 caaggtgtat gcgattcgcc cggttgcccg tacgttggaa gatcaatttt tggaagtgac
     1141 gggaggcggg tccattggct gatttcttca agctggtaca taatgaaaat cttaaaatct
     1201 acttgcgtgt gcgcacatgg atcatgctgg ggctgctggc ggtcatcacc gctgtgattc
     1261 cgatgctgat ttctctagtt tctgatcagg ttagtgtgtg ggatggcatc gcattgacaa
     1321 cgttgtttac atttttcctc aatacgacgt ttacggtcat tgtagctgct gattcggtgg
     1381 ctggcgaatt tacatgggga acgattaagt tgctgctcat ccgcccttgg actcgcagca
     1441 aaattttgtt gtccaagtat atatcggtga ttttgttcag cttgcttgga acaatcgttt
     1501 tggtcttgat ggttacgcta tcctcctggc tgatgttatc gaaggacgca ccagcgggct
     1561 ctgttccgct gttcagtgat ccgatatctt acgtaacgct gaacttcttg tatagctata
     1621 tcgccttatt cgtgaccatg gcttttgcat ttatgttatc cgcggtgttt cgttcgagcg
     1681 ctttggcgat tggtttgtcc ttgtttatga tgttcaccaa aacggtgtat aactctattg
     1741 gcttgttcag cacagatcgt tttgaatgga ccaaatacgt actctttacg catatggatc
     1801 tgaaaaaata tctagatatg ccgccgggta cagtaagttc caatctaacc ttttcgctcg
     1861 ctgtgctggc cgcttattat gtggttttta tcgcgattgc ctgggtggtt tttgtaaaac
     1921 gcgatgtctc cacctaaaca cgtatctctt agcatgtgtg attgaatgac acgaggattt
     1981 tggcaaaatg ctgagatcac aaaaaggaag tccaatgcct agccatttgg acttcctttt
     2041 ttgctatgtt ggcactgttt tattcagtat ctatgtcatt tttgctacat attctgtaag
     2101 tgtgggtata ttgtaatcta ttttcagcaa gaatcaatca atagggtcgg tttgcgttta
     2161 aagaagtaga gagaaacaga acaggggggc gtatgatatg ctgcaaaata atcgtttttt
     2221 tcgtctgact tcaggaatcg tcatgatatt gcttatcatt tacttgggca ccaaagtaag
     2281 ctttatattc agtcctcttg tatccttggt cagcttgctg gttgtaccgt tgatgctatc
     2341 ttttttcctc tattatttat tgagaccgat tgtagatgtc atggaacgga gaaaaatcaa
     2401 acgctcaatt tccatattgc tgatttattt ggttattggc gtgttactgt tcctcttctc
     2461 atggggagtg tggcctacgc tccgtgatca ggtaaccaat ttatttgaga acgcgccgaa
     2521 gcttattaaa agtctggttg atcaattgag ccaatggcgg cataatcaat ccttgagaca
     2581 agtactgcct ccgggtgaag acccgctgtc acaactgtca gatacgttaa acgaagcttt
     2641 ttcaacgctg tcagattatt cggtaaagct ggtatcgttc gtgtcctact tttttatcgt
     2701 attggctacc tttcccatat tgctgtatta catgttgaag gaaggaagca agtttggccc
     2761 caaaatgctt aacttctttc ctaaaaaata tcacaaggac gcgctggaag ttatggagga
     2821 tattgatagt gcgctcagca gctttatcgt cagtcgagtg ctgatcaatg tcgcgttggg
     2881 cttgatgatg ttccttggat ttttgattat tggtttgcct tatgccttgc tgcttgccgt
     2941 tatttcgatt ttccttaatt ttattcccta tgtgggggca gtagctgctt ctataccagt
     3001 ggttatcatt ggatttctcg aatcgccttc catggcgctc tggtcgctgg tggtggtgat
     3061 cgttgcacag caaattcagg ataattggct gtcgccgatt gtctttggca agcagctgga
     3121 cattcatccg ttgactgtcg tcattttatt gctagttggt ggcgacctgc tcgggatctt
     3181 gggtatcatt ttggttattc cattatatat gtgcggcaaa atcgtcatac gcaaggtgta
     3241 ccatttattt ttggaacgca gagtggagga tattatggag tgattggagg atgtactgga
     3301 tatataggag tataagccgg ccctatcccg cttcaggttg tagggaggct tggctgtcct
     3361 ctatgtcttg gctgaaactg gattgatttt catcctctga tttatctata gcagctggcg
     3421 actctgcatc catagtttgg ttcatttgac ttgtgccgtt cagtacgccg ccttcagaaa
     3481 tgaccaatgt aggggtcgcc gtatttccgt acagttcgcc tgttgatgta atggtcagcc
     3541 gtccttctgt ggtgatgctg ccgaatacct tgccggcaag aatgacgtcc cgtgcaatga
     3601 tgtccgaacg tacaactgct gattctccaa tgacgacagt gcgagtgctg tagatatcgc
     3661 cctgaaaatg accgtcaatg cgaatgttgg cctctgcctc aatcgtacct tcaaagctgg
     3721 tgccgttcgc gagcagtgta tccgtcgtcg ccggggtgga gagctttttt ttggattcct
     3781 tgaacatgat cgttttcctc caatccttta ttgtcggtat tttgcaaaac ccttattgta
     3841 catacagcaa tggatcaaca ggttggttat gcttgacgat ctgaaaatga agatgaggtc
     3901 ctgtgcttct cccggtactt cccagcaggc caatggtctg tcctttgtga acacggtccc
     3961 ccggagccac ctgcataccg cttaggtgca tataccagct ttgaagtccg tctggatgct
     4021 gaatgatgat gcacttgccg cgagctccgc tggaagcggc ctccagcaca gtgcctgccc
     4081 ctgctgcata gacaggatca ccggattgac cggcaatgtc cacgcctgag tgaaaagcgg
     4141 atttccctgt aaatgggtcg ctgcgatagc cgaaactgga ggtcatgcgc cgcgaaccaa
     4201 caggccaaat ggagggcctg ccttgttcag caagtgccag tcttcgggtc tggagcagct
     4261 gcgcggcttg ttggcgctcc aggttctgct gtacggcgtt tgcctgttga atagagcgcg
     4321 gaaccgtgcg ctccactgtg tccagcagag cttcgatttc ctgaaaatca tccatggcct
     4381 ggcgggctag aagagctgta ttttcatgca ctgcgatcaa ttcacccccg gtatggccgg
     4441 aagcatccca ggagaggggg gtgatggttg atttattact gcttgcgctg gaggaatttc
     4501 cgtgtttacg aatgaattgc tgcatttgtt gttccagctc agttacacgc tggagacgtt
     4561 cgcgaatact ggtggcttga ttcgtcagct ccatgacttc ctgccgcagt cgcccaatgg
     4621 ctgcgtcttt gtctgctacc gtgacctcca tctgcaaact ctggacagca agattggttt
     4681 ccatttggga aataatatgg gaagaacgga tttgcagccc gatcacgagc gtagagattg
     4741 atgcgatcac aagggtcggg acgagaatga cagcggctgc ggagcattgt agctgcttgg
     4801 gcggttgctg tgcatcccga atgacaagca gggtcatccg gcgatttagg cttccttttt
     4861 tcataatcgc tcctttccgg acatcgctcc tatagtgctt ggttactatc tattcagctt
     4921 aagaggcaaa catgtcaaaa aaattggagc tttgtataaa acgtagatat ataaggaggc
     4981 ttagacatgc tgtggttgct gttggtttta attattttta tttttcagac cgggacgatt
     5041 ctgctctttg aatttcgcaa gccgtccaaa gcggtagcct ggctctttat tttgttttgc
     5101 ttcccgctta ttggttttgt ggtgtactat tttgttgctc aggattacca gaagcgtaaa
     5161 gtggttcgta aagcaggatc gcagctattt cgtgaattcc gtgaacatct gtgggcgcaa
     5221 accaaggtga ttgaaaatgt agagcaaatg cacaatcccc atttcaagca tcaggagcgt
     5281 ctgtttaacc agttgattcg tatgtcggaa aacccgttga ctggctgcaa ccgtacacgt
     5341 gtgctgacga acggggaaga gactttcgac gccatgctga aagcgatgga acaggcacaa
     5401 catcatatcc atgtggagtt ttacatattt cgggcagacg aaatcgggaa aaaatttcag
     5461 gaggtcatga tccgtaaggc acgcgaggga gttaaggtac gattcattgt ggacggcgta
     5521 gggagctacc atttacccta ttcatttatt cgcacctgta atgaggctgg ggtcgaattt
     5581 cattattttc taccgccgtt tttcgccacg ctggaccgcc ggattaacta tcgcaatcac
     5641 cggaaaatcg tggtggtgga tggcacgatc ggatttgtgg ggggaatcaa tgtaggcgac
     5701 gattatcttg gaaagtaccc caaagtggga ttttggaggg atacgcattt gcagattgaa
     5761 ggagatggcg tttattttct gcaaaatgtg tttcttagcg attggaagct ggcttcggga
     5821 gagaggctaa tggacgtgaa tttatttcct ccacatacct gcaaagggga tgaggaagta
     5881 cagattttga gcagtgggcc cgatcaggta tgggatacga ttcaggaatt gtgttttgga
     5941 gcgcttacgg ttgccaaaaa gcggatttgg ataacgacgc cgtattttat tcccgatccg
     6001 gggatttatg aggcactgaa gctggcggcc gtcagcggca tagatgtgaa aattattatt
     6061 ccctaccaat cagattcgaa actggtccac ctggcgtcac tgtcctatgt gcaagaactg
     6121 ctggaggcag gagtggagtt ctaccaatat cgaaaaggat ttattcacgc taaagtggtg
     6181 attgtggacg atttgctcgg ctcggttggg accgccaata tggacatgcg tagctttttc
     6241 tataattttg agttgaccgc tgtacttttt gcaacttcgg cgttggaacg gctatcggca
     6301 gattttgtag aggacatttc caactcttcc aaaatagatt tgaacgtgtt ccgcagacgc
     6361 cctcgatctc aaaaaatagc tgaaattcta actcgcatgc tctctcccct cctttagagc
     6421 cggttttcgc cgtttttatc aatataatcc cgctttattg tgatttatgt gctctttgct
     6481 aacttttttg cgcaaaatca cagttttatg atatactaat cacataacta agcgccgtaa
     6541 aggagagggg actgcggaga gcagcccctt tttcggtcca atataccata ctgtaacggg
     6601 gggatttata tatgagtgta gtgagcaagg aagtccaaaa tctgtctgag atcacagatg
     6661 taaccggaga gttgaccaag atcagcaaaa ttccagctaa tccaaagaac aaagtaaaac
     6721 gcttattgca gcgtgcagcc atgatcgtgg ttggtgcagc gctgatggcc gtgggattgg
     6781 aaatattcct ggttcctaac ggcgttattg acggcggcgt tacaggtatt tccattatgg
     6841 cctccaagat tactggttat ccgctcggta ttttcctgac cctgttgaac cttccatttt
     6901 tacttatcgg ctacaaacaa atcggtaaaa ccttcgcttt atccacatta ttcggcatcg
     6961 tcgttatgtc catcggaact gcgttacttc acaatgtaag tgcattgacg cctggggaac
     7021 cgctgcttgg cgctatcttc gggggtgtca ttctcggcgt gggagtgggt cttgtgattc
     7081 ggtccggcgg ctcgctggat gggacagaga tcgtggctat tctcgtcagc gaaaaaactc
     7141 ctttttcggt cggtgagatc gtactgttcg ttaatatttt cattctggga agtgcgggtt
     7201 ttgtattcgg ttggccgaat gccctgtatt ccatgattgc ttattatatt gctatgaaaa
     7261 tgattgatat tacaattgag ggtctggatc agtccaaatc ggtctggatt attagtgata
     7321 aataccgtga tatcggagat gccctgacgg accgtcttgg acggggggta acttacctgg
     7381 aaggtgaagg cggctttaca ggcgagagca aaaaagtgat tttcgtcgtc attacccgac
     7441 tggaggaagc gaaactcaag agcatcgttg aggattggga cccgcacgcc ttcattgcaa
     7501 ttggtaatat tcacgatgtg aagggcggac gttttaagaa aaaaggaata cactagcgca
     7561 aggggacaat ttctcagcct atggctgcgg ggttcgtccc cttttttgtg cttcaaagca
     7621 tggattaggt tgggtgtgtt ttggagcgca tatgtttgag gaggtcctct acgggctggg
     7681 gaggcacctt gtcgatcaag tcgcctacct ggtttaaccg ttcctcaata tttagcaaat
     7741 ggtaatcaag tggtgacaca tcttgccgta cctcttccca ggttagcgga gtcgagaccg
     7801 tagcaccggg acgtgcccga ggagtataag gagcggctag ggtttttccc tgataatgct
     7861 gcaagtaatc aaaatagatg gctgttccac gatccttctt taaccgttcc agtgtgaaca
     7921 gatgcgggtg cttttccgtc acaaattgtc caaccaacag tccgatgctg cgtagctcgt
     7981 caaaggtgat gcctgtacgg atcgggacga taatttgtac acctgtggcc ccggaggttt
     8041 tggggacaga gtccaaccca agcgaagcca atacttcgcc tacaatggag gcggcctcca
     8101 taatacgtgg ctcgacttct ctggatggat ccagatcaat catccattca cagggcagtt
     8161 ggcttcctgt tctgtgcaga gagggatgaa attccaacgc agcttgatta ccgagccaga
     8221 gtagttgggg cagcttgcca agcacgatat actcaatgcc atcatgcaga gcggtttcaa
     8281 tatagtctgg ccgaggatgt ggggcatttt tctgataaaa aaaatctcca tggataccat
     8341 gtggccaacg gatgacagtc aatagacgct gatgacaata tttgagcagg tagggggcca
     8401 ataccgcaag cttgcgaaga tatagcgcct tagttacacc tgcttcgggc cacagcggtt
     8461 tatccgggtt tgtgatcgca atttcatgac cttcaatcgt aatcgtacct ttaacagctc
     8521 gtcccatagt gctatgctcc tttggttaac atgcagcaag atcattattt acagacaact
     8581 ggtagcattt ctacatctac ataaggttta acatgagcgt gcagcacaga atttatccat
     8641 caaagggatt gacaagatac attatgtatc ataaattata ataaaaatac gatatgtatc
     8701 tattaaaacg tcttgagcag aggtagagga ggagtgtgct tgattgaaaa gcagggcgga
     8761 aagctagtat ttctgttgag tgtccctcga agtggaagct cgctactaac tgccattttg
     8821 caaaaccact cccgtctgtt tgccacgcag gaaatgtggt ttctgctcag tttatatgct
     8881 cttcctcagt cacatgcacg gccatatgga ggaacaggaa tactccggca attttttaaa
     8941 ggtatggtcc ctccacatgt attggagcag gccgctcgtt cgtatgcact tgaaatatat
     9001 aatggcctgc ttcaagggac gaccgctgat atgcttatcg acaaatcacc gcgttactat
     9061 acagtgcttg aatttgtaga ccgtttgttc ccggctgccc gtcgagtgtg gcttatccgc
     9121 aatcctttgt ccatcgtggc ctcgtttaaa aaggtcaatc agctccgaaa tgggaacttt
     9181 cacctgctga aggaactggg aagtccgcat tttaatatga agatgacaga tattacggtt
     9241 ggtttgttcc ggtacgctca ttattttgcc acacctcatc cacttgcata cccgctgatg
     9301 tatgaacagc tcgtagccaa tccaaggatg gagattgaga agctgtgtca ttttctggag
     9361 atccattatg agccggggat ggaaaggtac gggaacttcg cggatacgcc ccaatccaat
     9421 cttttttata gcatgggagc gggtgatccg tttgttatgg agcatgaaca ggcgcatcag
     9481 aattcggtac atagttggca acatctgttg agtacaatgg aagttgaact gtattgcaga
     9541 agtattggag ctcgcttgtt taggcaactt ggttacggag aagcgctgga acaggctgag
     9601 cagatgactg gagtccgctt tgaggatgac ccggatgtag agctgttgag tcggcgtaca
     9661 caccagttcc tccaacaaag tggctttgaa tggaagacag cttatcggat gctggaagaa
     9721 caggatgcag ataacaaagg attcatgaca aatgcaacct gtcatgctgc acctcacaac
     9781 ccggcaagga tggatatggc acagatcgtg agtgatcgac gaattcaatc actggaaaac
     9841 agactggcac atagctttga ggaacggaac cggctgatcg cgcagctcca aagctatcag
     9901 cgcccaagcc aaggattccg gtcccattta ttggcccgta agttcgggcg ctgggcgtct
     9961 gaagtattat caagtatcgg aaaagaaaag gggggagaac gtgagtgcaa ttgccggaat
    10021 ctatagattt gggcatgagt ctgtatatgc tgaagaaggc gaaaaaatga tgcaaactct
    10081 gcaaaaatat cccgctgacc gcgtgtgcgc ttggtgtgaa ggttccattt ttttgggatg
    10141 tcatgcccag catgtgaccc cagaatctgt tcatgagcgt cttccctttt atgatgagct
    10201 aagagatttg gctataacgg ccgatgcgat cattgacaac cgttctgagc tgtttgaacg
    10261 actagcagtt gagcaggggc ggcggataga tatcacggac agcgagctga ttttactggc
    10321 atacgacaaa tggggtgttg atgcagcagg ttatctgata ggtgattttg cctttgtcat
    10381 ttgggatgct aagaaacatc ggttatatgg tgctagagat atgacaggca atcgtacgct
    10441 gtacacctac caacatgacg gaggatttgc gtttagcacg gtagtcgctc cgctattggt
    10501 tctgtcctct ctgcgaaaag aactgcatga accatggctg gccgaattct tatctatccg
    10561 tgcaatgcag gaatccgtcg atatcgggac aaccgcctac aagcatatca accagctacc
    10621 tcctgcacat tggttcacta tggaagaggg aaagcaatcg ctctgtaaat atgcatgtct
    10681 ggatgaggta gagccgttgc ggctcaatac aggcggcgaa tacatagaag ctttccgcga
    10741 ggtattctcc caggcggtaa ctgcccgatt acggacgcat cgcgctgtag gggctgccct
    10801 gagtggggga ttggattccg gagcggttgc cagctttgcc gcgccagcgc tgcacttaca
    10861 acacaagccg ctacatgcct acagctatgt acctgttcaa gattttacag attggacacc
    10921 acctacattg ctggcaaatg aacgcagcta tattcagtcc acggctcgct atgtgggtaa
    10981 tattcatgaa aattatatgg attttgaggg gaaaagcccg ttttctgaaa ttgatatttg
    11041 gctggagttg atggaggctc cctacaaata ttttgaaaac tccttctgga ttagaggttt
    11101 ttatgagaaa gcacaggaac ataatgtcgg agttctgttg actggggcac gcggcaactt
    11161 taccgtttcg tgggggcctg cactggacta ttatgcccgt cagtttcgcc gtttgcattg
    11221 gctgcaatct tggcagggag tgaggcggta tagcaagctt acaggcagtc gtatgtctca
    11281 tttactgccc gtgatgttga aaaaagccac tttacttgac gctcgcacat ggtggggacg
    11341 tggcaagcaa agtccgattc cttcactgat tcacccggag tttgccaagc ggatgaatgt
    11401 agaagatatt cccgtattga gtggaactgg ctggagaaaa aatgccgatc agacaagaaa
    11461 agagaagttt tcaaatttgg cgattgccaa caaaaatggt gtcatggcga ccaaactttc
    11521 actccgttat ggcctgtggg aacgtgatcc gaccggggac agccgtgtca ttcgcttttg
    11581 cttatcggta ccttttgaac aatatgtaca aaatggccgg gaccgtgccc tcattcgtaa
    11641 agctatgcgt gatcatctcc ctgatgatgt tcggttgaac cagcgagtac gcggcgtaca
    11701 gcctgcggat tggctacatc gtatgcttcc ttgctgggac acgtttatgg gagagctgca
    11761 agtgatgtgt catgatttac gagctgccga atatctcaat atggactaca ttaagacggc
    11821 tatggcgaaa taccgacatc cccgtccgga ccaggcatcc gatccgaata tacgactatt
    11881 catgcacagc ctgatcgtgt accgttttct ctgtggtttg aactgatttg gatctaaccg
    11941 atcagacggc gtgccattcg tgggagggga ggtgatgaga tgagtaaaaa agaatggcag
    12001 gaaccgacga ttgaggtgct ggatattaac cagactatgg cgggtaaagg ctggaaacag
    12061 attgattggg tgtcagacca tgatgccgat ctgtataatc cgagctaacg gaagataatt
    12121 atacatgagc cgatgttggg ctgagatcca aatagcttac tgatcacgag ccgtctttat
    12181 ttcattcggg ttaggttgga ccggaagaaa taaagacgga attttaagaa cagggagtga
    12241 gtcctatcgc gcatgacagg agtgcccata acagttgggt gaaatataca gcctttggac
    12301 tcaggattgc cagtgagctg actctgcctg agctgatccc agcagaaccg ggattggtag
    12361 aggatgtggt catccggcag gttgatttgt cagcatggag ggaccaactg gagcaggcca
    12421 attttgtaat gcagggtgaa cgctttatgt tcctaatacc ggacacggcc atttatgcca
    12481 tcaggggagg caaggaaatc gaggtaagta tgttgccaag ggctgatcct gacaccgtgc
    12541 ggttgtttgt actgggcaca tgcatgggtg ttctactgtt gcaaaaacgg gttttaccta
    12601 ttcacggaag tgcggtcgtc atcggaggtc gggtctatgc atttgtaggt gaatccggca
    12661 cgggaaaatc gacgctggct gctgccttta gacaggctgg ctatcagatg atcagtgatg
    12721 atgtgattgc tataaacgtg acagcttccg cagccatcgt atatccggca tatccgcagc
    12781 agaagctggg actggaaagc ttgcttcaat tggaggcatt acgggagaac aagtatgtac
    12841 ggcaaagaaa gcatgttctt tccctaactg acggtaatcc tgtaagggca caataccaag
    12901 atttgcgtag gatttcaggt gagctcaata aatatgccgt gcctgctgtg gacgaatttt
    12961 ataacgatcc gcttcccctg ggaggtgtat tcgagcttgt gagcgattct cccaaccgtg
    13021 agtcgatgcg tgaaggagag ccagtggtgg ttacggaaca gcccttgaac aaactggagt
    13081 gcttgcatac attactacag catacatatc gtagggcgat catttcgcga atgggtttgg
    13141 gtgaatggta ttttgataca gcggcccgga tggctcggaa agtggaaggc tggcggctgc
    13201 tgagggatag ctccttcttt acggcgtccg aggttgtaca acgcgtactt gagctcattc
    13261 ataaggagga aaagagttat ggcagccatt aatccagcta aggatcatta tcgcatcacg
    13321 tatggtgaag aggtctatgt aagtgatatg gacggagaaa aagtgatgat gagtattcat
    13381 acgggaaagt attataattt aggcttcaca ggaggacgga tctgggaact agctgaatcc
    13441 agtccttcac ttggagatat tgtaactgtc ctgacgaatg aatatgaagt ggacgaggaa
    13501 cagtgcagac agcaggtaca tacctttgta gctgaattgg agcgggaagg attgctgagg
    13561 ctcctacggg agttggacta acatgcggat acaacggctt cttctcttgt ctccagaggt
    13621 cgggagattg ttgccggaag cctggctgga gctgggatgc gcaagatttc gccagcgtcg
    13681 ttcttttgga gattactcag gggcttgggg gacatgtatg gaagaaactt cttggcagtg
    13741 cgagatcggg caggagaagt ctatccgtca catttcacaa gctgtggatg tagccagccg
    13801 ttatactcct tggcgcagta gctgtcttgt acaagccgct gccgctatga cgttgctggt
    13861 acgcagaaaa ctggactgta cactgtatct gggcacagcc aaaaatgctg cgggacaatt
    13921 ggcagcacat gcatgggtac ggagtgggcc gatctatgtt acgggagaac gggagatggg
    13981 agcgtttacc gtggtgggaa tattcgggag acgtgctggg acagctacaa atacgaggac
    14041 agcggataaa ggcagttctc tgttttagtt ttagtgcgat ataaaaggaa caaagaacgt
    14101 tcaaagaatc gaaggagaag aatccatgac caccaagtct attttggaac ttgcgaattg
    14161 gaatgaggat caagaattaa cgttgttact ctctctactt cgtaaagacg tcaatctatg
    14221 gcagaatacg atgactgctt cccagttgca ggagatcgat tggtcccgct tgctgcgtct
    14281 gacagaacac catcgtgtga tacctacggt gtatctccag ctgaaaacgt tgaatcaccc
    14341 gttcattccc gcagaattgc tgcgaaacct tcaggcgcaa tatcatcgaa acacgctgcg
    14401 catgctccat cttcaagcag aagccgagcg tctgaccagg ctgctcacag ctcatggaat
    14461 tcgtgtgctg atgttgaagg gtcctgctct ggcgcagcaa ttgtacgggg atgtttccct
    14521 gcgtacctct aaagacattg atttacttat tgccccggat gacatggatg aagcggagca
    14581 ctggatgaag gaagctgggt atgcgtccaa aagcggagaa gtgcgcgtcc ttggcagctg
    14641 gaagtggaag gatcatcatg cgtccttcct acatccgcaa aagagggtcg aagtcgagtt
    14701 gcactggcgg cttcacccgg atggggggcg ggagccctcc tttgatgagc tttggggctg
    14761 ccggcaaatg ggtaaagccc cagcagttcg agccagtcag atggcaccag cgacttctgc
    14821 cgacagcagg aatgtgacga catcctgcat gtatacgctt ggcagcgagc atcaatttct
    14881 gtacctcagc gcacacggag cgcgtcacgg ctggttcagg ctgcgctggt tggttgacat
    14941 tgacaggctt gcggtacgcg ctgtcgattg gggggcgcta ctgccgctaa tgcgccgtta
    15001 cgggggcctg cctgcgggcg ggcaggcttg ggcactggcc gctgcgctgt tgggtacgcc
    15061 gatcccggag ccgatgggtc cgatatcggc tacccggcag gcgcacaggc ttgcgctgag
    15121 cgcgctggct tttatgcagg ccagcgtccc tgcgccgtac ccggttgcca atggggcgga
    15181 tacaggcaga ctcgttcagc cagagctatt gcctaacgta gctttgaccg agtcaatgaa
    15241 taccgcccct tcggatggcg gtatttcagc taacggaacc tcgggcgaag ctgttctgta
    15301 cgccgtcagt agtgctgctg gcatatcgaa agatgccagc agcatccttg gtgacccggt
    15361 gaatacagtg aacactgctg taagtagcct tgccaagcct gtaggtgctg ctacagtcgc
    15421 ctccagtcca gccattgctg gagctacaac aacagcgttt actcctcaac cggttagccg
    15481 cgcttacctg ctttccttaa aggagccaag acacagacta tggtatctca tcagccgttt
    15541 gtttccttct acgagggatt cagtcatttg cccactgcct cgccagctgc attttttgta
    15601 tattccttta cgtccatttc tttggctaaa acgtcgattt tcaaagcact aacccgataa
    15661 ggagtgtaca tgatgactca tctgcgatta tatatgacca agctgtatag cgtgaacggc
    15721 ggggcgttat ttcttaatat tggatgtatg atgatcgtca gtctactgga gggtgtcggc
    15781 atttatatgc ttgttcctat gctggcggcc atcggcgtat ttggcggtca ttcagagatg
    15841 ccatttctgt cggatggatt tgattatttt ttgccgtaca ttcctaaaag ctggctgttg
    15901 ccggggatgc taatgttttt cgtcatgctg cttaccgggc aggcttggct tcagcgttac
    15961 cagtccattc ttaactcacg gattcagcag cgttttatgc gttcccttcg aatagacgta
    16021 tacacttcct ttatgaaggc gcagtgggct ttttatttgc gtcagcgtaa atctgatttt
    16081 agccacgtga tgacgaccga gctggcgcgt gtcagtcagg gaacgaattt gcttcttcaa
    16141 ctgaccacgg ccgtcatgtt tacgctaatc cagattgcgc tggctttttg gctatcccct
    16201 tctttaaccg ggctggtgtt tctgagtggc ttggtgttgt ttgtcgtgtt ccgtcgctcc
    16261 atccgaaatg ccaaacaatt aggtgaccgt accactgagc tgtcacagat ttattttgcc
    16321 ggaattacgg atcatatgaa cgggatgaaa gatattaaaa gcaatctgct ggaagcagcg
    16381 aatatccatt ggtttcgctc cctgacgcag cggatggagg ataatacgac tcagtttgtt
    16441 cggcaaaatg cgaccacaca gttttttcat cgcatagcgg cagctgtttt tgtcgttagt
    16501 gtcctatttg tgtcgctcca atggctgcat gttacacctg aaaaactgat cgtgctcatc
    16561 cttatatttt cccgcttatg gcccaggttt gcccttattc aagcgagcct ggaatatatt
    16621 atgtctatga tctctgcttt tgagagtgta actaaagtgc aacgggaatg cgaggctttc
    16681 tcagatcctt ctttaattgg gcttacatcc tctgagaatc atgtcccatt cgattcatcg
    16741 gtaaatcatt tgtcatctac atctgcacgg caacccctat cccttcgtaa tggaatagaa
    16801 tgcagccatt tggattattg ctacgagggt gcagcagtgt ctgcactacg tcatattaat
    16861 ttgttgatac ctgcccgggg aatgaccgcc attgtaggga aatcaggagc aggcaaaagc
    16921 acaatggtcg atgttctaat gggtttttta cgcccaacgg ggggacagat taaaatcgat
    16981 gatcatgtgc tggacgacaa attgctgccg ctgtggcggc agtcgtttgg ctatgtgtca
    17041 caggacccgt ttttgttcca tgcgaccgtc cgtgaaaatt tgaagctggc cgataaggat
    17101 gctagtgaac aacagctatg ggaggcgtta cattttgcag ctgcagacaa ctttgtatcc
    17161 agactgccag aagggctgga cacagtcatt ggtgatcgcg ggattcgttt gtccggggga
    17221 gagcgtcaac ggctggtatt agcgcgggct attttgcatc atcctcctgt actcatcctg
    17281 gatgaagcga caagtgcact ggatggtgag catgaggctg caattcaggc agcattggaa
    17341 cggatgaaag gtcaaatgac gttgatcgtg atcgctcacc gtctgtcaac gatcagacat
    17401 gcagatcaaa ttgttgttct ggatcaaggc gaggtcatac agcaggggaa ctaccaccaa
    17461 ctggtagaag aggagcgggg ggcgttcagt cagctacttt cgtatcaaag cactgtcagc
    17521 gccgcccctt agtcagcctt ttctataaag ctcaagtttc tttacgtttg gtgctacttc
    17581 ttctcttttt gactggagca ggagagatgg cgtcgcctgc cacagcttgt tgtgctgtca
    17641 cggctgctgg tttacgcgca ggacgttttt tcgcagcagg accaggatcg gtaacgacag
    17701 gcttcactgc ctcaatactg gcttggaggg cagccattaa atcaaccaca ttggtctgag
    17761 gctgtgttgg ggcaattcgc acctcttcgc cagctacttt atgctggata agatccagca
    17821 gacgctcgcg gtactgatcc gtatactttg ctgcatcaaa aggggtagat agctgctcaa
    17881 tcaacatttt tgccatggtc agctctttct ctttaacctc ctcctgtcca ggtaagttgg
    17941 gaacttgagc aatgggacgg atttcgtccg ggtaaaacat ggtctccacc gccaagcatt
    18001 catccagcac gcgaatggct gccagactgc ttttcgagcg gatggagatt tgggcaatcc
    18061 cgatttttcc ggtatccttc attgcattca tgagcagctt atacgcattg gagccggcct
    18121 gatccgggga caaataatac gttttctgaa agtagatcgg atcaatttcc tgtaaatcca
    18181 caaagtccaa aatcacgata tttttatcgg cttgcccgct aacttgctcc agttcctcct
    18241 tgtcgaacat gacaaatttt cctttttcat attcgtatcc ttttccaatt tcctcccatt
    18301 caacctcctt atcacaaaca gggcacttcc gtacatagct cagtggactc ccacattcct
    18361 tgtgaatata acgcatggaa atatccttgt cctcagtagc tgaaaacatt ttaactggca
    18421 catgaaccag cccaaagctg atcgcgcctt tccagactgt atgcataccg ccagtcctcc
    18481 ttttttaccc gcatatttca tatttcgatt ccggacaccc gggctgtgag catttccttt
    18541 ttcacttagt atgcttcgca caaaggaatg tatgaggtgc aaatgtaggc tacgaattgc
    18601 tttcacttgc gcatggtttc ggttttattg gtgaatgtta agtcatatcc gattcaaaag
    18661 gaggtacacc attgatgcct agaaaacctt atcctcagca gatcagtcat cgtgtggggc
    18721 aaagtcagat tgcctttcga gggcctgctg caggcgaaca ggatgcattg ccacccgagt
    18781 ttgctctttc acatggaacg ccgccgcctt ttcccgtagc tgtcgctcat gtggatttgg
    18841 aggctgtagt ttcaacttcg ccttctcata gctttccttc attggatgtg gaacggatta
    18901 tagacgaaga ctaggtgacc tatatttcta aatatcacaa aaacaatgag cagggggaga
    18961 acagtatgaa tgtggagcga gcaaaagcca tttatgattc atccgaaacg attgccgtcc
    19021 aattggatgg caaaccgatt tggattgagc atgtagatga agcgaatggt atggcaacga
    19081 tacagatcgg cagcagaccc ggcaatacac aaaccgttcg tgtggatcga ttggaagaac
    19141 aataggagag ggaatccaac ctaaaaaggc tcgcaattgc tcaatgagca attagcgaac
    19201 cttattttat ataataagtg attgtggaga caagttaaac gccaaacaag ttaatttgaa
    19261 ggtggaactg gtttttacac tgcaatggtc ttcaaatgtg gagaaaccat taactcagcc
    19321 tctgttgcca tttgaacatc ttccaccgac aaacctggag caatttcctt gagcatcagc
    19381 cctttacctg gaataacatc gatgacaccc ttttcggtta cgatggtctt taccacattt
    19441 acagcggtta ggggcagctt gcattgtttc agtattttcg gcgccccatt tttgttcaca
    19501 tgctccatag ctacaatcac tctcttggct ccaaccacca aatccatggc tccgcccatg
    19561 cccggcacct ttttccctgg gatcatccag tttgcaaggt tgcctttctc atcgacctcc
    19621 agagcaccca gaacggtaac gtccacatgc cctccacgta taatggaaaa tgaaagcgca
    19681 ctgtcaatat agcaggctcc tttcacggtt gtaacgtagt ttccgcctga atcgatacaa
    19741 tcgagtcttt cttttcccgg agctgctttg ggaccaacgc cgacaattcc gttctccgcc
    19801 tgcagcataa tattaacgtt ttcggggata tagtccactg ccatggtagg caatccaata
    19861 cccaggttga ccacttcgcc gtctttgaat tcctgggcta ttcttctaat aatcaattct
    19921 ctgttattca ttgtctccac ctacctttac aatcgcatcg acaaatattc caggaacatt
    19981 gatatgattg gggtcaattt caccggcctt aacgtattca tcggtctgag caactacata
    20041 ctcggctgcg gtagccatca ccaaattgaa gttgcgtgaa gagccgttga tgacaaggtt
    20101 ccctgcttca tcagctttat gggctctgat aagcgccaca tcggctttca gcggcagttc
    20161 gagcagatat tctctttcat caattttgat tttctttttt ccttcctcta caatggtgcc
    20221 tacacccaca ggggttaaaa taccacccaa accagcacca cctgcgcgta ttttttcagc
    20281 aagcgttcct tgcgggaaga gttgaacgtc cgcttctttt gtcatcaaga gccttcctgt
    20341 ttcgggattg gagccaatat aggatgcgaa aattcgcttg actcttccac tttttacaag
    20401 tctataaata gataattccg gtgtgcctgt gtcattggaa ataatcgtaa gattatcagc
    20461 ggaattggtg tctacaagcg cacgcaccag ctcctccgga atgcctcctt gcataaaacc
    20521 tccaaccatc actgtgtctc cgtctttaat tttcttaact gcttcttcag cggagtttac
    20581 ttttttattc atggttctgt ctccttatct attttttagg aagcaagctt tattggagat
    20641 aatcgtatag gactcttcca tatggaagtg ttaaatcggc aataaaatgt tttccgccaa
    20701 cataagctct aaccggcaaa tctgccaccg gagcgttgac atgggggatc aggcttaatc
    20761 tggcaggtcc tgaccaggcg ccttttacag taatatcttc gagattatac gccactaact
    20821 gagcaatttt aggggtaccg tccacatcag gaattaattt cagattaact tgcgtttttg
    20881 cgatggcttt agccgtttcc ttttcatcaa gaacgttata tttgaaaggg gtggttccca
    20941 tggctaccag ggcgttatta taatgcaagg tacccgtcag cgtctctgta tcctcaacga
    21001 tcaggcgagg tttcgcccat tttttcggaa atccccagat ttcacgtccc cccagaatag
    21061 caggtgcgtt atccagatac atttgggcaa caaaattaca cggttctcca ttataagtac
    21121 acggaatgac aatgccgctt tcctcatagc ttcctaaacc ggatgaatcg ggcattttga
    21181 tccattcata ggaaaccgta ttacttccat ccggctgaag aggttcaggg accgcctgtc
    21241 taatcgccgc gggatcggat tcataggtaa taataaagaa ttcccggttg atgaaccggc
    21301 atggcggacg tccataacta ccactggccg caggcatgga ttggagtgaa agtacatctt
    21361 tttgattcat agcgatctcc cttccttttt aagaggtatt tcaacaatta tcttgaacaa
    21421 gcactttaaa tgagagcatt ttcaaccagc atggctattc ccattcccgt tccaatgcat
    21481 aacgagacta cgccataacg tgaagatctg cgtaccattt catgaaccaa cgtaaccaat
    21541 actctagcac cgcttgcacc aacagggtga ccgattgcga tcgcgccgcc attgacattg
    21601 actttctctg gattaactcc aagctctttt tgcaccgcta gagcttgtgc agcgaacgct
    21661 tcgttaattt caaagagatc aatgtcatct atagacattc cctgtttctt cagcagtgac
    21721 gaaatggctt ttaccggtcc cattcccata tatgcagggt caacaccaac aagcgagtaa
    21781 cctttgatat atgctaacgg ctttaacgca tgttccttac atttgtcttc cgacacgact
    21841 agcatagccg ccgcaccatc attgatgccc gaagcgtttc ccgcagtaac cgttccgttc
    21901 tctttaaacg caggttttaa ctgagaaagt ttttctttcg tcgtatttcc tcttatgtgt
    21961 tcgtcctctg tgaaataagt agtttctttt ttgtttttga tcatgaccgg aacaatttgc
    22021 tcttcaaaaa ccttgttgtt ttttgcttcg acagccttta tctggctttc ataagcaaat
    22081 gcatcttgct caagtcttga aattccatat ttttctgcaa cattttcggc ggtaattccc
    22141 atatggtaat ggttgatcgg gcatgttagg ccatcggcca ccaaggagtc taccaattca
    22201 ccgttaccga gcttgtagcc gtttctagca ttttttagca gataaggggc gtttgacatg
    22261 ctctccatgc caccggccaa gacgatgttt ccttgttctg ccaatatgga atcgtaagct
    22321 aacgcgacgg catgaagccc tgaaccgcaa accgtgttta tcgttgattc gggtacatca
    22381 atggggatac cggcttttag tgccgcctgt ctggcaggat tttgaccatt gcccgcttga
    22441 agaacatttc ccataaaaat ttgatcaatc aaagaaggct ctaatttact ttgctgaagg
    22501 catgctgtca tcatggttgc tcccagttca ggagcgctta ggggggcaag agctttatta
    22561 aatgaaccga ccgctgttct caacgggctt actatagcta cttttttcat aatcacattc
    22621 ctttcgctgt gttcaaggac acaatacatc catgactgca cttccattcg taattccggt
    22681 cctaacctac gaaacgtaaa aactgcaaga tacatttaca tgcgggcata tcatggtgcc
    22741 taagacagtg agtatgacgg tccgatcgcc ttctttcctt tctggaaatt aaaaccagaa
    22801 ttatcatagt tctaatacag attttgctca atgttcaaat ctttacatag atccaaatac
    22861 agatgtttat agagccatat cgtccacatt aagtaggtca ttctaatgtt ttctgttaat
    22921 ttcttgattt ttctgaaaat agtgatcaaa aattgaattt tatgttaaat acgaaagtgc
    22981 aaatcaatct gtgaaaaaaa tttcttggta aatttcattt agctcatcgc aggggaaaac
    23041 tccctctata tgtaaattcg caaccgactt atagcatcta aaagagcaaa gcaggttgcc
    23101 aatccaaatg aatacatttg gaattcggat aaatatcaat ccatatatgt ctgggccacc
    23161 tatagcattg acgttataac gtcagtgttt ttttatttgc tcgggtgaac aaaaaagaag
    23221 ccgactgctt gaaagcaatc ggcttggaac gtaaaaattt cacttcaaca gctcacgaaa
    23281 aatgtacgtc tgccgtcgtg agcaaacgcg caaaacgatt acctagcact gcattgtgat
    23341 gagctacgat ttgttcgccg cttagtacct tgctatcaaa tgtactatgc gcatccgata
    23401 cgagcacgtt gttctggtat cccagactat aggcacttcg gcaagtcgtg tcgagacaaa
    23461 attcagtctg cattccggca ataatcagct ggcttgcccc caatccctgg agcacatcac
    23521 gcaattcagt ttggtagaag ctgtcccagg atgattttcg gacaattcgt tcctgaggaa
    23581 gaggacgcac cacgtctgcg atggcccagc ctagactgtt ttcccggaaa tcctcatccg
    23641 cttcatcggt atgctgcacg aaaatgaccg gtgtaccaga agctctggct tcggttaaaa
    23701 gctgctgcaa atgcgccaca acttcctgtt cacgatacag cttctcatca tacatgaaca
    23761 tagcctgctg aacatcaatc aagagtaaaa cggtttgtcc catcagttcg attccctccc
    23821 tatgtgtaac acttaactta caatagcatg tcttcatgcc ttgcggcgac ataaggtgaa
    23881 ctatataata aagaacaagt tggaacggtc cgattcggac gaaaggtgat taaaagagat
    23941 gacaatttcg caggaacagt ttgtattccg ttctgtctca gaggcacaga ccgggacatt
    24001 agcaggcttt ttggcagccc aagcggttcc cggaaccgtg attgtgctgg atggagatct
    24061 gggagcgg
//
