LOCUS       NZ_JAIQCI010000014     23259 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Croceicoccus hydrothermalis strain JLT1
            NODE_16_length_184612_cov_165.724792, whole genome shotgun sequence.
ACCESSION   NZ_JAIQCI010000014
VERSION     NZ_JAIQCI010000014.1
KEYWORDS    WGS; RefSeq.
SOURCE      Croceicoccus hydrothermalis
  ORGANISM  Croceicoccus hydrothermalis
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Erythrobacteraceae; Croceicoccus.
REFERENCE   1  (bases 1 to 184696)
  AUTHORS   Chen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2021) State Key Laboratory for Marine
            Environmental Science, Institute of Marine Microbes and Ecospheres,
            Xiamen University, A3-302, Zhoulongquan Building, Xiang'an, Xiamen,
            Fujian 361102, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 2019-11-6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 521.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022378335.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 07:11:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,506
            CDSs (total)                      :: 3,455
            Genes (coding)                    :: 3,380
            CDSs (with protein)               :: 3,380
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 30 of 75
            Pseudo Genes (incomplete)         :: 44 of 75
            Pseudo Genes (internal stop)      :: 22 of 75
            Pseudo Genes (multiple problems)  :: 17 of 75
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:29:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 161437
            Orig. end                         :: 184696
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAIQCI010000014.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23259
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..23259
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23259
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[20000:21029](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21029
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     misc_feature    360..374
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.45"
                     /tool="antismash"
     misc_feature    complement(449..464)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.52"
                     /tool="antismash"
     gene            complement(594..1352)
                     /locus_tag="K4G67_RS10165"
     CDS             complement(594..1352)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017979698.1"
                     /locus_tag="K4G67_RS10165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_239806267.1"
                     /transl_table=11
                     /translation="MNDRETNPVAPTALVTGSTRGIGKAIADTLRRRGVHVITHGSGAG
                     PVGGGQIAADLDDPAAPAQLWVDALAAARDAGRTRIDILVNNAGLFDAAPIDLSDIAWL
                     DAWDRTLRINLSSAAQLSRLAVRHWQEDGDGGGRLVNIASRAAYRGDSPDHWHYAAAKS
                     GLVAMTKTIARHYARDGVLAYTVCPGFVDTAIAGDYLESRGGAQLLRDIPLGRVARPEE
                     IARIAAFCALDAPESMTGAVIDANGASFVR"
     gene            1560..1970
                     /gene="sdhC"
                     /locus_tag="K4G67_RS10170"
     CDS             1560..1970
                     /GO_component="GO:0045282 - plasma membrane succinate
                     dehydrogenase complex [Evidence IEA]"
                     /GO_function="GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sdhC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007014762.1"
                     /locus_tag="K4G67_RS10170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="succinate dehydrogenase, cytochrome b556 subunit"
                     /protein_id="WP_239806268.1"
                     /transl_table=11
                     /translation="MADARGGNRLAKPRPLSPHLSIWKWGPAMAVSILHRVSGNAMATV
                     GLLILLWMVGAIAAGPDAYADFAAVMGSWIGIIVLIGISWSFFNHMSSGIRHLVLDVGA
                     GYEVDRNNRWSTISILTGILLTVAFWAVVLLA"
     gene            1989..2369
                     /gene="sdhD"
                     /locus_tag="K4G67_RS10175"
     CDS             1989..2369
                     /GO_component="GO:0045282 - plasma membrane succinate
                     dehydrogenase complex [Evidence IEA]"
                     /GO_function="GO:0000104 - succinate dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sdhD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018075360.1"
                     /locus_tag="K4G67_RS10175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="succinate dehydrogenase, hydrophobic membrane
                     anchor protein"
                     /protein_id="WP_239806269.1"
                     /transl_table=11
                     /translation="MGNGTRIGRVRGLGSAHEGAHHWLLQRFTAVGNLVLVLWLVFSLL
                     TLPDYGYLTMASWLSSPLAATAMVLLIISTFWHARLGMQVMIEDYVHGANRFAAIVAMN
                     LFFVAGGVFGIVSVIRIALGGA"
     gene            2371..4191
                     /gene="sdhA"
                     /locus_tag="K4G67_RS10180"
     CDS             2371..4191
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /GO_process="GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sdhA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014075521.1"
                     /locus_tag="K4G67_RS10180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="WP_239806270.1"
                     /transl_table=11
                     /translation="MADASTQPAYQIIDHTYDTIVVGAGGSGLRATMGSAEAGLKTACI
                     TKVFPTRSHTVAAQGGIAASLGNNTPDHWSWHMYDTVKGSDWLGDQDAIEYLVREAPQA
                     VYELEHAGVPFSRNPEGTIYQRPFGGHMQNMGEGPPVQRTCAAADRTGHAMLHALYQQS
                     LKYDADFFIEYFAIDLIMVNGECKGVIAMCMDDGSIHRFRGHAVVLATGGYGRSYFTAT
                     SAHTCTGDGNAMVLRAGLPLQDMEFVQFHPTGIYGAGVLITEGARGEGGYLTNSEGERF
                     MERYAPSAKDLASRDVVSRSMALEIREGRGVGAESDHIFLHLDHIDPKVLAERLPGITE
                     SGKIFAGVDLTRQPLPVVPTVHYNMGGIPTNYHGEVMTIGADGNPETVVPGLFAVGEAA
                     CVSVHGANRLGSNSLIDLVVFGRATGHRLKELVKPGTSHDGLPSDSADFALSRLDHFRH
                     AKGGSPTAQIRGEMQRTMSGHAAVFRTDELMQEGKAKLEQVYRRMEDIHVTDRSLIWNS
                     DLIETLELDNLISQATVTMHSAANRKESRGAHAHEDYPERDDANWMKHTAAWFDGWGGK
                     GGGVKIDYRPVHDFTLTDDVKYIEPKKRVY"
     gene            complement(4713..5309)
                     /locus_tag="K4G67_RS10185"
     CDS             complement(4713..5309)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K4G67_RS10185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_239806271.1"
                     /transl_table=11
                     /translation="MTPSHDDTPETLARRKQAARAMRRCWTMTGTAVLLTGLGLAACAP
                     TVREPAPTVPAPPPIPVPAPPPPVPVPDDWRDAPISMGEWTYRADANATRALFGSDVAD
                     FVMACEPGNRQIKLWRMTPDARATTMTITTTSQTKMLTAQPAANGQVVATLAPHDPIID
                     AMIFSRGRFAVAAPGTRTLYMPTWAEIARVAEDCR"
     gene            5413..6162
                     /locus_tag="K4G67_RS10190"
     CDS             5413..6162
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008070317.1"
                     /locus_tag="K4G67_RS10190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_239806272.1"
                     /transl_table=11
                     /translation="MPAPAKPAKTRVDQLLVDRGHAESRTRAQALVMAGLVFTGETKIA
                     KPGQQIRSDAALDVRGRDHPWVSRGGIKLAHALETFALDPTGAVAMDIGSSTGGFTDVL
                     LQNGAAHVVAVDSGTNQLAWKLRQDERVTVLEQTSARILTPGHITQGCNWVVCDASFIG
                     LAKVLEVPLALAAAHATLVALIKPQFEVGRGEVGKGGVVRDPALHERVTGEVRDWLTSI
                     GWTVRGLTQSPITGPEGNVEFLIWAQR"
     gene            6198..6878
                     /locus_tag="K4G67_RS10195"
     CDS             6198..6878
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015060.4"
                     /locus_tag="K4G67_RS10195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TspO/MBR family protein"
                     /protein_id="WP_239806273.1"
                     /transl_table=11
                     /translation="MTDPNTHPDNRQTPRENASTTPVSARVGDADRHDDGVDDDTDGPG
                     MPAAHAEHGSEPVDATPAHVPAHRQKSLLWWALLCVPAVVAAGLVVGQLSGSGESDPWF
                     ASLVKPDLYPPGWLFGVVWTILYALMGFALALVVASDRRAYKGSAVAVFLIQLAVNLAW
                     SPIFFGAHLIGMAFFWILLMLVLIITTMAIFAKVSRLAAALLVPYLAWVSFAAILNLQI
                     WQLN"
     gene            6905..7216
                     /locus_tag="K4G67_RS10200"
     CDS             6905..7216
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016280.4"
                     /locus_tag="K4G67_RS10200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="accessory factor UbiK family protein"
                     /protein_id="WP_338026424.1"
                     /transl_table=11
                     /translation="MQSDNPRISDLTRMITAAAGTFAGMGREASEAARERFKEAMGGLD
                     FVSREEFEAVKQMAAAARTQNDALAARIARLEAKHAGDGDDTAQSDASPKQPDDYTGL"
     gene            complement(7700..9784)
                     /locus_tag="K4G67_RS10205"
     CDS             complement(7700..9784)
                     /EC_number="1.11.1.6"
                     /GO_function="GO:0004096 - catalase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008602743.1"
                     /locus_tag="K4G67_RS10205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="catalase"
                     /protein_id="WP_239806274.1"
                     /transl_table=11
                     /translation="MKDFELSQGGANHQKPAGKDDVMTTAQGAPIADDQNWLTAGPRGP
                     QLLEDQIAREKIFHFDHERIPERVVHARGYGVHGEFELTDPIPEFTRAGVLSGEKGKKT
                     PVFTRFSTVAGNKGSPDLARDVRGFAVKFYTEEGNWDIVGNNIPVFFIQDAIKFPDLIH
                     SVKPAPDRGFPQAQSAHDNFWDFASLSPESMHMIMWQMSDRTIPRSFRFMEGFGVHTFR
                     LVNAEGKSHFVKFHWKPKQGMQSVIWNEALKINGMDPDFHRRDMWNAIDAGDYPQWDLG
                     VQIFDEEFAENFEFDVLDATKIIPEEQVPVRIIGTMTLNNNVDNFFAETEQVAFCTQNI
                     VPGIDHSDDPLLQGRNFSYLDTQLKRLGGPNFTHIPINAPKCPVRHFQQDGHMAMHNPK
                     GRANYEPNSWGGDTGEDRGPRACPMNGFTSYEAPVTGPKVRVRSETFADHYSQARQFYI
                     SQTEIEQRHIANALTFELSKVERMDIRKRMVGHLRHIDADLAQAVCDGIGLTELPEKVP
                     LAREPITDLPPSDALSILKNGPDSFKGRKLGIYVAKGGDAAIVDALKTAAMDAGAMVEI
                     IAPHVAGAELSDGKMIEASEKIDGGPSVVYDAVALVMGEDAAKNYADDKPSIDFVNDAF
                     AHAKFIAYVPETMALLKGAGVDGKIDDGFVKLTGAGDAKTFVETCGKLRYWDRMAVKQD
                     "
     misc_feature    complement(9838..9853)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.78"
                     /tool="antismash"
     misc_feature    9929..9943
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            9955..10563
                     /locus_tag="K4G67_RS10210"
     CDS             9955..10563
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008070327.1"
                     /locus_tag="K4G67_RS10210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="recombination protein O N-terminal
                     domain-containing protein"
                     /protein_id="WP_239806293.1"
                     /transl_table=11
                     /translation="MHLRAPAILCASRPHGETAAIARVLTRKYGMVAGYVAGGRGRGLR
                     PVLIPGNAVAADIAARAASQLPFMKLELLQSRAPWMTEPLPAAAIQWATALTASCLPER
                     NPYPAVHDALGPLLDAICHAPSAPGWAVALLRYETLLLREMGYGAAGGTDAQDWDATLA
                     ALEAQGRTIATRLLAERRGDVMAARALLMARLTRITGES"
     gene            10560..11615
                     /gene="leuB"
                     /locus_tag="K4G67_RS10215"
     CDS             10560..11615
                     /EC_number="1.1.1.85"
                     /GO_function="GO:0003862 - 3-isopropylmalate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009098 - leucine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="leuB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007011345.1"
                     /locus_tag="K4G67_RS10215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="WP_239806275.1"
                     /transl_table=11
                     /translation="MKIAVFAGDGIGPEVTEQAVRVLKELPLPLSLITGDVGGAAYRLH
                     GHPLPDETLVAAREADAVLFGAVGDPSCDTLDRHLRPEQAVLGLRRELGLFANLRPAKM
                     FPGMEDASGLKPEIASAIDLLIVRELNGDVYFGEKGMRTTDANLREGYDIMSYDESEVR
                     RIAVTGFEAARKRRGKLCSVDKANVLETSQLWRDVVIEVSADYADIELSHMYVDNAAMQ
                     LVRDPGQFDVIVTGNLFGDILSDQASMCVGSIGLLASASLGERKTAHGTFGLYEPIHGS
                     APDIAGKGIANPLATILSAADLLRHSLGQAEQAERVERAVAATLSDGVLGRDLGGTATT
                     ADIGDAVIARL"
     misc_feature    11648..11661
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.9"
                     /tool="antismash"
     misc_feature    complement(11667..11683)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     gene            11789..12226
                     /locus_tag="K4G67_RS10220"
     CDS             11789..12226
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K4G67_RS10220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_239806276.1"
                     /transl_table=11
                     /translation="MTAPRPMSRPYDRRRPFAFAALEIGAFLFALACVAASQPDTHSSI
                     AAYLIANVIGILSVTRLRLNMVRLVMMGIYAVGIIGVVTSLAFRFDAAMRMPDILLRAS
                     LVIGYGAVTTVLLMSAPVAPWCRSGNLPFFDRMKSRLDLFR"
     gene            12236..13387
                     /locus_tag="K4G67_RS10225"
     CDS             12236..13387
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007678720.1"
                     /locus_tag="K4G67_RS10225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_239806277.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.7e-27,
                     bitscore: 89.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPARAASRAAGRQGGARGDRVLDLAIVLPTLNERENIAAFIARL
                     ADTLGPVRWEVIVVDDDSEDGTADAARMLARADMRVRVIQRIGRRGLASAAIEGMLATA
                     APHVAVMDADHQHDPALLLPMLRAMEGGDLDLCIASRFAPGASTQAWAAPEREARSHLA
                     NRIARAMTGIAATDPMSGFFMIRADLLRMLAPRLSGIGFKILLDILATAPAPLRLREFP
                     MNFAARIAGESKLDRAIAFDFLIGVYDRTIGRVLPTRFALFGTIGAVGVAVHLAILWLF
                     HKAAGTDFLTGQIAAVAGALTFNFLLNNALTYADQRLSGARAMLAGWARFAGTCAVGAG
                     ANVAVAEALAGRGFHWLSAALAGIVVGSVWNFALSSRFVWGRF"
     gene            13465..14535
                     /locus_tag="K4G67_RS10230"
     CDS             13465..14535
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF010077.0"
                     /locus_tag="K4G67_RS10230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PAS domain-containing protein"
                     /protein_id="WP_239806278.1"
                     /transl_table=11
                     /translation="MADKQQDGGSQAGQEFEPATARSSAADFDAMSPDLARMFHQSAEQ
                     TRMAICISDARAPDMPIVYANQAFLHLTGYEKEEVVGRNCRFLQGPDTDPDTVARVREG
                     LENERVRVTILRNYRKDGTPFWNSLHIGPIYDREGTLTHFYGSQWDVTELLDERERMAI
                     AERLNQEMDHRSRNLFGVISAMIRLSVKSAEDKFDLADKLSERVIALSRAHSVSSRTDG
                     NVHEADLRELIEAILLPYTDVARDRIAIIGDTIMLDKKQVTPLGLVLHELATNALKYGA
                     LSTADGAVSVDWTQENGKTVLFWRETGGPMLDDDPPRQSGSGSRIMLGVLSNINATMTQ
                     DWEKDGLLVRIAIPVE"
     misc_feature    complement(13499..13514)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.02"
                     /tool="antismash"
     gene            complement(14537..15805)
                     /locus_tag="K4G67_RS10235"
     CDS             complement(14537..15805)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000030 - mannosyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006493 - protein O-linked glycosylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014425.4"
                     /locus_tag="K4G67_RS10235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phospholipid carrier-dependent
                     glycosyltransferase"
                     /protein_id="WP_239806279.1"
                     /transl_table=11
                     /translation="MAAAIAITALFGVVAAWHIARIETPIFDEIHYLPAARDWIAGETL
                     RNAEHPLLGKQLLALFMGVFGDDALGWRIGSVVFGMLTLFSAMRAVWHVSHRGFATIAT
                     GVLIATDFTLLVQARIAMLDIYMLGLGAAGIWACAAALDSGRVAAARVRLGAGGVLLGL
                     AVAAKWNAAPLPVFAGLAFAWGRWRALPRDGRGGLHILTARDAGPVRGVSLIEAAGWLG
                     LLPVAVYLLHFMAIAALSDPPPQWHDPISWQAHMLSLQQGVTTPHTYMSRWWQWAANSR
                     AIWYFYEVYDGAQRGILLLGNPLTMLAALPALAYGVYCGARHGRGDMALAAWGWIAAMA
                     LWIAAPKPVQFYYHYLLPSLFAMAALAFMLDRAVWETRFRVWAIPFLAASLSLFVWFLP
                     VLTGQALAGRDSFLDYAWIEGWR"
     gene            15931..17139
                     /locus_tag="K4G67_RS10240"
     CDS             15931..17139
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_5 (94-223). E-value: 2e-10.
                     Score: 32.0. Matches aSDomain:
                     nrpspksdomains_K4G67_RS10240_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008997156.1"
                     /locus_tag="K4G67_RS10240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_239806280.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.5e-09, bitscore:
                     30.2, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 2.8e-07, bitscore:
                     23.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRYTGTDRSITQSWKPATRAVRAGTMRSEHGETSEALYLTSGYS
                     YDDAATPAARFAGEAAGMTYSRLQNPTVAMLEERIAVMEGAEACRTQASGMAAMTAALL
                     SQLSAGDHIVAARAAFGSCRWLVDSLCPRFGIESTTIDSTDNDAWERAIRPNTKVFFFE
                     TPANPTLDIVDLRAVCDIARAHGITTVVDNAFCTPVMQRPIEWGADVVAYSATKLMEGQ
                     GRVLAGAVCGTEEFINETLLPFQRNTGPNLSPFNAWVVMKGLETLELRARQQCANALKV
                     GQFVETRVPRILHPGLESHPRHNLAMKQMDMTGCIFSFVLDGGRAQAHAVLDGLELIDI
                     SNNIGDSRSLMCHPASTTHAGLSAEARAEMGVDEGMIRFNVGLEDADDIIADLDRAFDR
                     AGL"
     aSDomain        16213..16599
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_K4G67_RS10240_Aminotran_5.1"
                     /evalue="2.00E-10"
                     /label="K4G67_RS10240_Aminotran_5.1"
                     /locus_tag="K4G67_RS10240"
                     /protein_end="223"
                     /protein_start="94"
                     /score="32.0"
                     /tool="antismash"
                     /translation="GMAAMTAALLSQLSAGDHIVAARAAFGSCRWLVDSLCPRFGIEST
                     TIDSTDNDAWERAIRPNTKVFFFETPANPTLDIVDLRAVCDIARAHGITTVVDNAFCTP
                     VMQRPIEWGADVVAYSATKLMEGQG"
     gene            17136..18515
                     /locus_tag="K4G67_RS10245"
     CDS             17136..18515
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011446308.1"
                     /locus_tag="K4G67_RS10245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PAS domain S-box protein"
                     /protein_id="WP_239806281.1"
                     /transl_table=11
                     /translation="MSLSPLDVEGRDADGGLPAGSLLSAIVEGADDAIISCLLDGRVLS
                     WNRAAERLFGFRAEEMIGQSIDMLIPEDRMEEEADIIARLAAGETLTSFQTVRLRKDGA
                     PLCVSLTTSPVRDASGTIIGASKIIRDSGSWHAARDALARSERRFHMLADNIAQLAWIA
                     EPDGAIHWYNRRWYEYTGTNEEDMAGWGWKAVHHPDHVERVVREFRACIAAGTYWEDTF
                     PLRSADGEYRWFLSRAKPVHDAEGRLMSWFGTNTDITNQRDQAAAIENLLTEVNHRVKN
                     TLATIQVLARRSAPGHDDFVKRFVRRIEALTINQDLLIDRRWGEVPVGDLVDAQLGFVR
                     RRVGDRLRSEGPDVLLSARSAETLGLALHELATNALKHGALADEEGEVRVMLEVEDGEF
                     TMRWSEAGGPPVKAPDFMGFGSAVIRDVPAATFDGEAVLDYTPEGLCWRLTCPLDAVAA
                     H"
     gene            18597..18995
                     /gene="apaG"
                     /locus_tag="K4G67_RS10250"
     CDS             18597..18995
                     /codon_start=1
                     /gene="apaG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011414572.1"
                     /locus_tag="K4G67_RS10250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="WP_239806294.1"
                     /transl_table=11
                     /translation="MNRFFNHVAHSNGITVRVAANFLPEQSRVTAGRWFWSYHVRIENH
                     GDEPVQLLTRHWRITDANGRVSLVDGDGVVGEQPFLDPEQAHDYVSGCPLETPHGTMEG
                     HYTFRRDDGTIFEAAIPFFPLDAPTAIR"
     gene            19127..19924
                     /locus_tag="K4G67_RS10255"
     CDS             19127..19924
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017665150.1"
                     /locus_tag="K4G67_RS10255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_239806282.1"
                     /transl_table=11
                     /translation="MKRTHLPLNGLRVLDAAARHLSFTRAADELAVTPAAVGQQIRALE
                     DLLGVVLFRRTPKGLELTDEARAGLDPLREGFLRFEESVQAMQSGQSSHFFTFAAPRDF
                     FGAWLAARLAAYRAENAETRFLMAGGQNTDFTEANLDFAVRLVEGPGELEGVPLSPGRR
                     IAVAAPGADDAWIAWPGHPAPEGVEPGLQVGATGQALSAALGGMGRALLPMQLVESALA
                     DGTLVAVGEPEETRATYWLVAPRPQWRQRKMKALVDYLTAAPQ"
     gene            20001..21029
                     /locus_tag="K4G67_RS10260"
     CDS             20001..21029
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012421.4"
                     /locus_tag="K4G67_RS10260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-oxoacyl-[acyl-carrier-protein] synthase III
                     C-terminal domain-containing protein"
                     /protein_id="WP_239806283.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 3.9e-19,
                     bitscore: 62.5, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 2.5e-13,
                     bitscore: 43.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHILSIGTAVPPHILPQSDVVPILTDALGHAPPPRLASILTNTG
                     IAQRHIAEDIGYYFRPRRASERAATFERVATALWEDAAQDALTRAGLTPADIGTIVTVC
                     TTGTLTPSIPSRALQRMGFAPTTRTVPVFGWGCAGGGLGLSLAATLADAARGEGALLLV
                     CVELCSLAYDHSSMEKKDLVALALFSDGCAAAVIAPGDGPNRLGPFAQHCWPDTIPMMG
                     WEIGDTGFDLVLSRDIPRFVEKDFAPFCDAFLAAQSLTRAGLAEPACHPGGGRVVEALA
                     AMFGRDLPATAAVLRDYGNMSSPTVLFILDRLLSNSAPGGEPVLVTALGPGFTGTAALV
                     HR"
     gene            21026..21547
                     /locus_tag="K4G67_RS10265"
     CDS             21026..21547
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004671 - protein C-terminal
                     S-isoprenylcysteine carboxyl O-methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006481 - C-terminal protein methylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1150: isoprenylcysteine carboxyl methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF016062.4"
                     /locus_tag="K4G67_RS10265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isoprenylcysteine carboxylmethyltransferase
                     family protein"
                     /protein_id="WP_239806284.1"
                     /transl_table=11
                     /translation="MIAQWASWPVWAWAVLAYVVASRLGELAYARRNTRRLLAEGGIEH
                     YPGHYPLFIVLHGSWLFAILLFAQPAPEPSYALASLFAFSQAARYWVLHSIGRWWTTRI
                     ISAPHFPRVRRGPYRFFPHPNYAVVVAEIALLPLLLGAPWVALVWSVLNAMLLAHRIRL
                     EEKALFLREG"
     gene            21587..22537
                     /locus_tag="K4G67_RS10270"
     CDS             21587..22537
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="K4G67_RS10270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_239806285.1"
                     /transl_table=11
                     /translation="MPPRLHPFAHEVELRIDPRAHLVLVAERLRAPLLFERFVNRVARP
                     RHRGLAIAVRTTMAQHEHDQRLVMPPPFADDFAARHDGPRLPLDRAGKRGILKPRDPAI
                     DRTLPRSGEPLGALAAAQRIERLDTRPDAPRGLRDAARGGKHGDKAALTIGRDRIAPGT
                     GMHERREIEQRIARFRLLGGKGDVARPPRRPRRPAMQRRIGIGLADHAITRIPAITLLV
                     GNAHDPPPPRPPCVTRRIAQPRPVPRRAKRLRPGAIPQLVQRRHANADLGRGIADEPAP
                     RERRDKLPLRLCIQLAPFLLHRRGKGKIDHDTLRH"
     misc_feature    complement(22648..22663)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.91"
                     /tool="antismash"
     misc_feature    22703..22718
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.13"
                     /tool="antismash"
     misc_feature    complement(22830..22844)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     misc_feature    complement(22844..22860)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.77"
                     /tool="antismash"
     misc_feature    complement(22847..22860)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.15"
                     /tool="antismash"
     misc_feature    complement(22848..22861)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.46"
                     /tool="antismash"
     misc_feature    22849..22862
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.55"
                     /tool="antismash"
     misc_feature    complement(22908..22917)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.81"
                     /tool="antismash"
     misc_feature    23103..23117
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
ORIGIN
        1 gcggtttgcg gcggcattgt cgatgacgac atcgtggcac accgcgtcga tgtcgctcgc
       61 ggtggcgagc gcgcggggcc acagatgcat cgcggcaaag gcgagcagcc ccgtgcccgt
      121 cccgatgtcg gcgatattgc gcacgaccgc gccctgcgcc cgcatcgcgt ccagcatttc
      181 gaggcaaccg gcggtcgtcc gatgctgccc ggtgccgaac gcctggcttg ccggaatgac
      241 gaagcttttg attccggggg catcgctcgc cggatggtcg ggcgtgtgga cgtggaaacg
      301 gcccgcggtg atcggctcga ccccctgctg gctcaacgtg acccagtcct cctcgggcaa
      361 tttttcagcc gatagcggcg gcggcgtgtc gaacagggcg gcgatcgcgg cgtgatcctt
      421 tttggtcggg cggcgcggca gatacgcgtc gagccgccat tcgagcggtt tctgctctgc
      481 aatctcgcat ccggtgacga cgatatcgtc gtcccagtcg gcgctgtcct cttgccgcaa
      541 gagcgcggca tgcaccgcat cgcgcggggc gaaggccgtg atgatccagc tcgtcatcgc
      601 acgaagcttg cgccattggc atcgatcacc gcgccggtca tgctttccgg ggcatcgagc
      661 gcgcagaacg cggcgatgcg cgcgatctcc tccggccgcg ccacccggcc gagcggaatg
      721 tcgcgcagca attgcgcgcc gccccggctt tcgaggtaat cgcccgcgat ggccgtatcg
      781 acgaagccgg gacacacggt ataggccagc acgccgtcgc gcgcataatg ccgggcgatg
      841 gtcttcgtca tcgcgacgag gccggatttc gccgcggcat agtgccagtg atcgggcgaa
      901 tcgccgcgat aggcggcgcg gctggcgata ttgacgagcc ggcccccgcc atcgccgtcc
      961 tcttgccagt gccgcacggc aagcctggac aattgcgccg cactcgacag gttgatccgc
     1021 agcgtgcggt cccacgcgtc gagccatgcg atgtcggaca ggtcgatcgg tgcggcgtcg
     1081 aacaatccgg cattgttgac gaggatatcg atgcgcgtgc ggcctgcgtc gcgcgcggcg
     1141 gcgagcgcat cgacccacaa ttgcgcaggc gcggccggat cgtcgagatc ggccgcgatc
     1201 tgcccgccgc cgacggggcc ggcgccgctt ccgtgcgtaa tcacgtgcac gccgcgccgc
     1261 cgcagcgtgt cggcaatggc cttgccgatg ccgcgcgtgc tcccggtgac gagtgcggtc
     1321 ggggcgacag ggttcgtttc tcgatcgttc atcgcctttg gttagggccg cacgccgcgc
     1381 atcacaaggg gacagcgcgg cgaaggaggg caggacagtg cctgccgccg ccccgccaaa
     1441 cggcgagttc atgccaattc gcccttgccc tcttggcgcc atggtgccat tcgcggacgc
     1501 aacaccacat atgaccgcgc gtggcccgca cggtcatggc aagcgcaggg gaagaaccta
     1561 tggccgatgc aaggggcgga aaccgcctgg cgaaaccgcg tccgctttcg ccgcatctct
     1621 cgatctggaa atggggaccg gcgatggccg tctccatcct gcaccgcgta tcgggcaatg
     1681 cgatggcgac ggtcggcctg ctcatcctgc tgtggatggt cggcgcgatt gccgccgggc
     1741 cggacgccta tgccgatttc gccgccgtca tgggaagctg gatcgggatc atcgtgctca
     1801 tcgggatttc ctggtcgttc ttcaaccaca tgtcttcggg catccgccac ctcgtcctcg
     1861 acgtgggtgc gggctacgaa gtcgatcgca acaatcgctg gtccacgatc tcgatcctga
     1921 ccggcatttt gctcaccgtc gccttctggg cggtggtgct gctggcctga cgaaagggga
     1981 tacgaaccat gggtaacgga accaggatcg gccgcgttcg cgggctcggc tccgcgcacg
     2041 aaggcgcgca ccactggctg cttcaacgct ttaccgccgt cggcaatctc gtgctcgtgc
     2101 tctggctggt gttcagcctt ttgacgctgc cggattacgg ctatctgacg atggcctcgt
     2161 ggctgtccag cccgcttgcg gcgacggcga tggtattgct catcatttcc accttctggc
     2221 acgcgcggct cggcatgcag gtcatgatcg aggattacgt gcatggcgcg aaccgtttcg
     2281 ccgccatcgt ggccatgaac ctgttctttg tcgcgggcgg tgtgttcggc atcgtgtccg
     2341 tgatccgcat cgcgctggga ggcgcataag atggccgacg cttcgacaca gcccgcctat
     2401 cagatcatcg accacaccta tgacacgatc gtcgtgggtg cgggcggttc cggcctgcgc
     2461 gccaccatgg gcagcgcgga agcgggcctg aaaaccgcct gcatcaccaa ggtgtttccg
     2521 acccgttcgc acaccgtcgc ggcacagggc ggcatcgccg catcgctcgg caacaatacg
     2581 cccgatcact ggtcgtggca catgtacgac acggtcaagg ggtccgactg gctcggcgat
     2641 caggacgcga tcgaatatct cgtgcgcgag gcaccacagg cggtgtacga gctcgaacac
     2701 gccggcgtgc cgttctcccg caatcccgaa ggcacgatct atcagcgtcc cttcggcggc
     2761 cacatgcaga acatgggcga aggccccccg gtgcagcgca cctgcgccgc cgccgaccgt
     2821 accggccacg cgatgctcca cgcgctgtat cagcaatcgc tgaaatatga cgcggacttc
     2881 ttcatcgaat atttcgcgat cgacctcatc atggtcaatg gcgagtgcaa gggcgtcatc
     2941 gccatgtgca tggacgatgg ctcgatccac aggttccgcg gccatgcggt cgtgctggcc
     3001 accggcggct atggccggtc ctatttcact gccacttccg cgcacacctg caccggcgac
     3061 ggcaatgcca tggtgctgcg tgccggcctc ccgctgcagg acatggaatt cgtgcagttc
     3121 cacccgaccg gaatctacgg cgcaggcgtg ctcatcaccg aaggcgcgcg cggcgagggc
     3181 ggttacctca ccaattccga aggcgagcgt ttcatggaac gctacgcccc ttcggcgaag
     3241 gatctggcca gccgcgacgt ggtttcgcgc tccatggcgc tcgaaattcg cgaagggcgc
     3301 ggtgtcggcg cggaaagcga ccatatcttc ctgcacctcg atcacatcga tcccaaggtg
     3361 ctggccgaac ggcttcccgg cattaccgaa agcggcaaga tcttcgccgg tgtcgatctc
     3421 acgcggcagc ctttgccggt ggtgccgacg gtccattaca acatgggcgg catccccacg
     3481 aactatcacg gcgaggtgat gaccatcggc gccgacggga acccggaaac cgtggtcccc
     3541 ggccttttcg cggtgggcga ggcggcctgc gtgtcggttc acggcgccaa ccggctcggc
     3601 tccaactcgc tgatcgatct cgtggtgttc ggccgcgcga ccggccaccg gttgaaggag
     3661 ctggtgaagc ccggcacgtc gcatgacggc ctgccgtcgg acagcgccga tttcgcactg
     3721 tcgcggctcg accatttccg ccatgcgaag ggcggctcgc ccaccgcgca gatccgcggc
     3781 gagatgcagc gcaccatgtc gggccacgcc gccgtgttcc gcacggacga gctgatgcag
     3841 gaaggcaagg ccaagctgga acaggtgtac cgccggatgg aggacatcca cgtcaccgac
     3901 cgttcgctca tctggaacag cgacctgatc gagacgctgg aactcgacaa tctcatcagc
     3961 caggcgacgg tgacgatgca ttcggccgcc aatcgcaagg aaagccgcgg cgcccacgcg
     4021 cacgaggatt atcccgaacg cgacgatgcc aactggatga agcacaccgc ggcctggttc
     4081 gacggctggg gcggcaaggg cggcggggtg aagatcgact atcgcccggt gcacgatttc
     4141 acgctgaccg acgacgtcaa atatatcgaa ccgaaaaagc gcgtgtacta aaacgctgcc
     4201 agggggccgg ggtcgtatga tcccggccct ttttcgggcc cgcgcggatg ggcgacgaaa
     4261 cagagaaagc ccgaagccgg tatccccgct tcgggctttc gcatggtcag cggccggaag
     4321 tgccgccctt gggtgccttt atcgcctcag acgttcggcg ataatgctcc ccggacattt
     4381 tccgacctct gtgctggacc atgagacatc ggatcacctc ctttcgcgac gggattcagg
     4441 gatgccgtgc ggcgcaaggt cccgcgttgc cttgcggacg gccggaccgg ggcacgcggt
     4501 gcgcagcgcc actttcctgc gccgcaatct gcgtcccccg cggcgttcag gcaagacttg
     4561 aattcgaaaa tttcgctgtc atgatcgctg acttcgcgtg cggcgatgca ccatgcgtgg
     4621 cccgaatttg cgcctcctcg accagtgccg ccgatcgccc gtcatcatgc cgcgacacgc
     4681 gcccggcgct tatccccggc gaatcgctgg ctttaccggc aatcctcggc gacgcgggca
     4741 atttcggccc atgtcggcat atagagcgtg cgcgttcccg gcgccgcgac ggcaaagcgc
     4801 ccgcgcgaga agatcatcgc gtcgatgatc ggatcgtgcg gcgccagcgt cgccaccacc
     4861 tgcccattgg ccgcaggctg cgcggtgagc atcttcgtct gcgaggtggt ggtgatcgtc
     4921 atggtcgtcg cccgcgcatc gggggtcatg cgccatagct tgatctgccg gttgcccggc
     4981 tcgcacgcca tcacgaaatc cgccacgtcg gacccgaaca gcgcgcgggt cgcattggca
     5041 tcggcgcgat aggtccactc gcccatcgaa atcggggcgt cgcgccaatc gtccggcacc
     5101 ggaaccggcg gcggcggggc gggaacgggg attggcgggg gcgccggcac cgtcggggcg
     5161 ggttcgcgca ccgtcggcgc gcacgcggcc agccccagcc cggtgagcag caccgccgtc
     5221 cccgtcatgg tccagcaacg gcgcatggca cgcgcggcct gtttccggcg ggcgagcgtt
     5281 tcgggcgtat cgtcatggct tggcgtcatc gcgcgcttat gcgaagagga cgcgcccggc
     5341 acaagcggca aacgtcgaac cggtccgccc ccgcgatttc gcgtttcgaa caccaccgga
     5401 tagccacgca ccatgcccgc acctgcaaaa cccgccaaga cccgcgtcga ccaattgctg
     5461 gtcgatcgcg gccatgccga aagccgcacg cgggcgcagg cgctcgtcat ggcggggctg
     5521 gtattcacag gcgagacgaa gatcgcgaag ccgggacagc agatccgcag cgatgccgcg
     5581 ctcgacgtgc gcgggcggga ccatccctgg gtgtcgcgcg gggggatcaa gcttgcccac
     5641 gcgctcgaaa cctttgcgct tgatcccaca ggcgccgtcg ccatggacat cggcagctcg
     5701 accggcggat tcaccgacgt gctgctccag aatggcgccg cgcatgtggt cgcggtggat
     5761 tccggcacga atcagttggc atggaaattg cggcaggacg aacgcgtcac cgtattggaa
     5821 cagaccagcg cgcgtatcct gacgccgggt catatcacgc aaggctgcaa ctgggtcgtg
     5881 tgcgatgcga gcttcatcgg cctggccaag gtgctcgagg tgccgctcgc gctcgccgcg
     5941 gcgcatgcaa ccctcgtggc gctgatcaag ccgcagttcg aggtgggccg cggcgaggtc
     6001 gggaagggcg gcgtggtgcg cgaccccgcg ctgcacgaac gcgtcacggg ggaggtgcgc
     6061 gactggctca ccagtattgg ctggacggtg cgcggcctca cgcaaagccc gataaccggg
     6121 ccggagggca atgtcgaatt cctgatctgg gcgcagcgct gagggaacgg agcgggccgc
     6181 gcctgcgttt tgatgccatg acagacccga acacgcatcc cgacaatcgc cagacccccc
     6241 gcgaaaacgc gtcaacgacg ccggtctcgg cgcgggtcgg cgacgcagac cggcacgatg
     6301 acggcgtcga tgatgacacg gacgggcccg gaatgcccgc cgcacacgcc gagcacggct
     6361 ccgaacccgt cgatgcgacg cctgcgcatg tccctgccca tcggcagaaa tcgctgctgt
     6421 ggtgggcgct gctctgcgtg ccggcggtgg tcgcggcggg gctggtcgtc gggcagcttt
     6481 cgggttcggg ggagagcgat ccgtggttcg cctcgctggt aaagccggac ctctatccgc
     6541 cgggctggct gttcggcgtg gtttggacga tcctctacgc gctgatgggg tttgcccttg
     6601 cgctggtggt ggcgagcgac cggcgcgcgt ataaaggttc cgcggttgcg gtgttcctga
     6661 tccagcttgc ggttaatctt gcctggtcgc cgatcttttt cggcgcgcat ctcatcggga
     6721 tggcgttctt ctggatcctg ctcatgctcg tgctcatcat cacgaccatg gcgatattcg
     6781 cgaaggtcag caggctcgcg gccgcgctgc tcgtgcccta tcttgcctgg gtgtcgttcg
     6841 cggcgatcct gaacctgcaa atctggcagt tgaattgaac gcggaaaagg accacattcc
     6901 caccatgcaa agcgacaacc cccggatctc cgacctcacc cgcatgatca ccgccgcggc
     6961 cggcacgttt gccggcatgg ggcgcgaagc gtcggaggcc gcgcgcgaac gcttcaagga
     7021 agcgatgggc gggctcgatt tcgtcagccg cgaggagttc gaggcggtga agcagatggc
     7081 cgccgccgcc cgcacgcaga atgacgcgct cgccgcccgc atcgccaggc tcgaggcgaa
     7141 acacgcaggc gacggcgacg atacggcgca aagcgacgcc tccccgaaac agcccgacga
     7201 ttacaccggg ctctgaccct atcgcgccgg ttcaggcgcg ctgatcccgc acagtggcct
     7261 gtttctgcgt aggggatacg gacctgcgcg ggttttcact atcgcacgga cacgggaacc
     7321 gggccttgcg tcccgcctct gatccttgcc cgatggcgcg gaaatatcct gttgtctacg
     7381 gggcgctacc caatcgaacc cgttcgcgtg cgcgcaaagg tccaagcgca tgccaccggg
     7441 gtgaacgacg gggcgcagga gcataggtcg atccgggggc acggcaaccg ccgcaaccgc
     7501 cgcgaccggc gaatccggcg cgcgctccat ccatcggtcc gtatgtaccg cactgcctca
     7561 tggggcgggc gaaaacgcgc gggtcgcaca gaacaggatc gcgcccgcta cggctccacg
     7621 cgcgagccac cggggcggat acgaaaacgg cggacgggat cgctcctgtc cgccgtttcg
     7681 cgtttccggt ttggcaggat cagtcctgct tgaccgccat ccggtcccag tagcgcagct
     7741 tgccgcatgt ctcgacaaag gttttcgcat cgcccgcgcc ggtcagcttc acgaagccgt
     7801 cgtcgatctt cccatcgacg cccgcccctt tcagcagggc catggtttca ggcacgtatg
     7861 ctatgaattt cgcgtgggcg aaggcgtcgt tcacgaaatc gatgctgggc ttgtcatcgg
     7921 cgtaattctt cgccgcatcc tcgcccatca ccaatgccac cgcgtcatag accaccgacg
     7981 gcccgccatc gatcttctcc gacgcctcga tcatcttgcc gtcggacagt tcggccccgg
     8041 cgacatgcgg ggcgatgatc tcgaccatgg cgccggcatc catcgccgcg gtcttgagcg
     8101 cgtccacgat ggccgcatcg ccgcccttgg cgacatagat gccgagcttg cgccccttga
     8161 agctgtccgg cccgttcttg aggatcgaca gcgcgtcgga cggcggcaag tcggtaatcg
     8221 gctcacgcgc cagcggcacc ttctccggca gctcggttag accgatgccg tcgcacaccg
     8281 cctgcgccag atcggcgtcg atatgacgca gatggccgac catccgcttg cgaatgtcca
     8341 tgcgttccac cttcgacaat tcgaaggtca gcgcattggc gatatgcctc tgctcgattt
     8401 cggtctggga gatatagaat tgccgcgcct ggctgtaatg gtcggcgaag gtttcgctgc
     8461 gcacgcggac cttgggccct gtcaccggcg cttcgtaact ggtgaacccg ttcatgggac
     8521 aggcgcgcgg gccgcggtcc tcgcccgtat cgccgcccca gctgttcggt tcgtaattgg
     8581 cgcggccctt ggggttgtgc atcgccatgt ggccgtcctg ctgaaaatgg cggacagggc
     8641 atttgggcgc gttgatcggg atatgggtga aattgggccc gccaagccgc ttcaactgcg
     8701 tgtcgagata gctgaaattg cggccctgga gcaggggatc gtccgaatgg tcgatgcccg
     8761 gcacgatgtt ctgcgtgcag aaggccacct gctctgtttc ggcaaagaaa ttgtcgacat
     8821 tgttgttcaa agtcatcgtg ccgatgatgc gcaccggcac ctgttcctcg ggaatgatct
     8881 tcgtcgcgtc cagcacgtcg aactcgaaat tctcggcgaa ttcctcgtcg aaaatctgca
     8941 cgccgagatc ccattgcggg taatcccccg catcgatcgc gttccacatg tcacggcgat
     9001 ggaaatcggg atccatgcca ttgatcttga gcgcctcgtt ccagatgacc gactgcatcc
     9061 cctgcttcgg cttccagtgg aacttcacga aatgggattt gccctccgca ttgacgaggc
     9121 ggaaggtgtg gacgccgaac ccttccatga aacggaacga gcgcgggatg gtgcggtccg
     9181 acatctgcca catgatcatg tgcatggatt cgggcgacag cgaggcaaag tcccagaaat
     9241 tgtcatgcgc gctctgcgcc tggggaaagc cgcggtcggg tgcgggcttt accgaatgga
     9301 tgaggtcggg aaacttgatc gcgtcctgaa tgaagaacac cgggatattg ttgcccacga
     9361 tatcccagtt gccttcctcg gtatagaatt tcaccgcgaa gccgcgcacg tcgcgggcaa
     9421 gatcgggcga acccttgttc cccgccacgg tcgaaaaccg cgtgaacacc ggcgtcttct
     9481 tccccttttc gccggacagc acgccggcgc gggtgaattc ggggatcgga tcggtcagct
     9541 cgaactcgcc atgcacgcca tagccccgcg catggaccac gcgttcggga atgcgttcgt
     9601 ggtcgaagtg aaagatcttc tcgcgcgcga tctgatcttc gagcaattgc ggcccgcgcg
     9661 gcccggcggt gagccagttc tgatcgtcgg cgatgggcgc gccctgcgcc gtggtcatca
     9721 catcgtcctt gccggcgggc ttttgatgat tggcgccgcc ttgtgacagt tcgaaatctt
     9781 tcatgatggg gtgcagcctt ctcgcttgcg ttaaccttac ccgcaccaac tgtcggtgtg
     9841 aaaaaaggtt gcgcggtaat tccgcctgcg cgcaatcggt tttggcgata taaacatgtg
     9901 ttggttgccg cgccggactt gcggcgcacg ccgatccgtt ccatcccgca ggtcatgcat
     9961 ctgcgcgccc cagccatcct ctgcgcctcg cgcccgcacg gcgaaaccgc ggcgatcgcc
    10021 cgcgtgctga cgcgcaaata tgggatggtt gccggatatg tcgcgggggg gcgggggcgg
    10081 ggcctgcgcc ccgtgctcat ccccggcaat gcggtcgcgg ccgacatcgc ggcccgcgcg
    10141 gcgagccagc tgcctttcat gaagctggaa ctgctgcaaa gccgggcgcc ctggatgacg
    10201 gagccgctgc ccgctgccgc aatacaatgg gcgaccgcgc tcacggcgag ctgcctgccc
    10261 gaacgcaatc cctacccggc ggtgcacgat gcgctcggcc cgctgctcga cgcgatatgc
    10321 catgcaccct cggcgccggg ctgggcggtg gcgctcttgc gctatgaaac gctgcttttg
    10381 cgcgaaatgg gatatggcgc ggcggggggc accgatgcgc aggactggga cgcgacgctc
    10441 gccgcactgg aggcgcaggg acgcaccatc gccacgcgcc tgcttgcgga gcggcgcggc
    10501 gatgttatgg cggcgcgcgc gctgttgatg gcgcggctta cacggatcac gggggaatca
    10561 tgaagatagc ggttttcgca ggcgacggca tcgggcccga agtgacggag caggcggtgc
    10621 gcgtgctcaa ggaactgccg ctgccgcttt cgctcatcac cggcgatgtc ggcggcgcgg
    10681 cctatcgcct tcacggacac ccgctgcccg atgaaacgct cgtcgccgcg cgggaggcgg
    10741 atgccgtgtt gttcggcgcg gtcggcgatc cgtcctgcga cacgctcgac cggcatctgc
    10801 gcccggaaca ggcggtgctg ggcctgcgcc gcgaactcgg cctgttcgcc aatctgcgcc
    10861 cggccaagat gtttcccggc atggaggatg ccagcggtct gaaacccgaa atcgcctcgg
    10921 ccatcgacct gctcatcgtg cgcgaactga acggcgatgt ctatttcgga gagaagggca
    10981 tgcgcacgac cgacgcgaac cttcgcgaag ggtacgacat catgtcctat gacgaaagcg
    11041 aggtgcgccg catcgccgtc accgggttcg aggccgcgcg caaacgtcgc ggcaaattgt
    11101 gcagcgtgga taaggccaac gtgctggaaa ccagccagct gtggcgcgac gtggtgatcg
    11161 aggtgtcggc cgattacgcc gatatcgaac tcagccacat gtatgtcgac aatgccgcga
    11221 tgcagctcgt gcgcgatccc ggacaattcg acgtgatcgt caccggcaat ctgttcggcg
    11281 acatattgtc ggatcaggca tcgatgtgcg tcggctccat cggcctgctc gcctccgcct
    11341 ctctggggga gcgcaagacc gcacatggca ctttcggcct ttacgaaccc attcacggga
    11401 gcgcgcccga catcgccggc aagggcatcg ccaatccgct ggccacgatc ctgtcggcgg
    11461 cggatctgct gcgccattcg ctcggccagg cggagcaggc ggagcgggtc gagcgtgcgg
    11521 tggccgcgac attgtccgat ggcgtacttg gccgcgacct tggcgggacg gccaccacgg
    11581 cggacatcgg cgatgcggtg atcgcgcggc tttgacccgt aaggcggggc atggcgggca
    11641 accgttccgc atgcggatgc aacatatggc aacgtttttg cagcgtcctg cgttgggaag
    11701 gggtctggtc gccgatgcgg cgtctgaccg gtggttccgc ttatccatgg taaacggaat
    11761 cgacatgccg cgatgacagg aacgtcgaat gaccgcgccc cgccccatgt cacgaccgta
    11821 cgaccgccgc cggcctttcg cttttgcggc gctcgaaatc ggggcgttcc tgttcgcgct
    11881 ggcttgcgtg gccgcgtctc aacccgatac ccactcttct atcgcggcgt atctcatcgc
    11941 gaatgtcatc ggcattcttt cggtgacgcg gcttcggctc aacatggtcc ggctcgtgat
    12001 gatggggatt tacgccgtcg gcattatcgg ggtggtgacg tcgctggcct ttcggttcga
    12061 tgcggcgatg aggatgcccg atatcctgct gcgcgcatct ctggttatcg gctacggcgc
    12121 cgtgacgacg gtcttgttga tgagcgcacc cgtcgcgcca tggtgccgtt cgggcaattt
    12181 gccctttttc gaccggatga agagccgcct cgacctgttc cgataggggc aggagatgcc
    12241 gccggcccgt gccgccagcc gtgcggcggg gcggcagggc ggggcgcggg gcgatagggt
    12301 gctcgacctc gcgatcgtcc ttcccacgct gaacgagcgg gagaatatcg ccgcgttcat
    12361 cgcgcggctg gccgacacgc tcggccccgt aagatgggag gtgatcgtcg tcgacgacga
    12421 cagcgaggat ggcaccgccg atgccgcgcg catgctggcg cgggcggaca tgcgcgtgcg
    12481 ggtgatacag cggatcggcc gccgcggcct cgccagcgcc gcgatcgagg ggatgctggc
    12541 aaccgccgcg ccgcatgtcg cggtgatgga cgccgatcat cagcatgacc ccgcgctgct
    12601 cctgcccatg ctgcgcgcga tggaaggcgg cgatctcgac ctgtgcatcg ccagccggtt
    12661 cgcgccgggg gcaagcacgc aggcctgggc cgcgccggag cgggaggcac gctcccacct
    12721 cgccaatcgc atcgcgcgcg ccatgacggg catcgccgcg accgacccga tgagcgggtt
    12781 cttcatgatc cgcgccgacc tgctgcgcat gctcgcgccg cgattgtcgg gcatcgggtt
    12841 caagattttg ctcgacatcc tcgccaccgc gcccgcgccg ttgcggctgc gcgaatttcc
    12901 gatgaatttc gcggcgcgga tcgccggcga atcgaaactc gaccgggcga tcgcgttcga
    12961 tttcctcatc ggcgtgtacg accgcacgat cgggcgggtg ctgcccacgc gctttgccct
    13021 gttcgggacc atcggcgctg tgggcgtggc ggtgcatctg gcgatcttgt ggctgtttca
    13081 caaagccgcg gggacggatt tcctcaccgg acagatcgcg gcggtcgcag gggcgctgac
    13141 gttcaatttc ctgctcaaca atgcgctgac ctacgccgat caacggctgt cgggtgcgcg
    13201 cgccatgttg gcggggtggg cgcggtttgc gggcacctgc gcggtcgggg cgggcgccaa
    13261 tgtcgccgtg gcggaggcgc tggccgggcg gggttttcac tggctgagcg cggcgctggc
    13321 cgggatcgtc gtcgggtcgg tctggaactt tgccctgtcg agccggttcg tctggggccg
    13381 tttttgattt gttcctgctg gaaacaactg ggccttcgtg tattaatccg ctgacttcat
    13441 ggacgaataa ggcggcggcg ggacttggcg gacaagcaac aggacggagg cagtcaggcc
    13501 ggacaggaat tcgagcctgc gacggcgcga agcagcgcgg ccgatttcga tgcgatgtct
    13561 cccgatctcg cccgcatgtt tcatcaatcc gccgaacaga cgcgcatggc aatctgcatc
    13621 tcggacgcgc gcgcgcccga catgcccatc gtctacgcga atcaggcgtt tctgcacctc
    13681 accggatatg agaaggaaga ggtcgtcggc aggaactgcc gcttccttca agggccggac
    13741 accgatcccg acaccgtcgc ccgcgtgcgc gaagggttgg aaaacgagcg cgtgcgcgtc
    13801 accatcctgc gcaattaccg caaggatgga acgccgttct ggaactcgct ccatatcggg
    13861 ccgatctacg accgggaggg gacgctgacg catttctacg gctcgcaatg ggacgtgacc
    13921 gaattgctgg atgagcgcga acgcatggcg atcgcggagc gcctcaatca ggagatggac
    13981 caccgcagcc gcaatctgtt cggcgtgatc agtgcgatga tccgcctctc cgtcaaatcg
    14041 gcggaggaca agttcgatct ggcggacaag ctttcggagc gggtcatcgc cctgtcgcgt
    14101 gcgcattcgg tatcctcgcg caccgacggc aacgtgcacg aagccgattt gcgcgagctg
    14161 atcgaagcga tcctgctccc ctatacagat gtcgcgcgcg accgtatcgc gatcatcggc
    14221 gatacgatca tgctggacaa gaaacaggtg acgccgctcg gtctcgtgct gcacgaactg
    14281 gcgaccaatg cgttgaaata cggggcattg tcgacggcgg acggggcggt atcggtcgac
    14341 tggacgcagg agaatggcaa gaccgtcctc ttctggcgcg aaaccggcgg gcccatgctc
    14401 gacgatgatc cgccgcgcca atcgggttcg ggatcgcgga tcatgctggg cgtgttgagc
    14461 aatatcaacg ccaccatgac acaggattgg gaaaaggacg ggcttctggt ccgcatcgcg
    14521 atcccggtgg agtgagctat cgccacccct cgatccacgc atagtcgagg aagctgtccc
    14581 gcccggccag cgcctgcccc gtaagcacgg gaagaaacca cacgaacagc gagagcgacg
    14641 cggcaaggaa cgggatcgcc cacacgcgaa accgcgtttc ccacaccgcg cggtcgagca
    14701 tgaacgcaag cgccgccatc gcgaacagcg agggcagcag gtaatgatag tagaactgca
    14761 ccggctttgg cgccgcgatc cataaggcca tcgctgcgat ccacccccac gcggccagcg
    14821 ccatgtcgcc ccgcccgtgc cgcgccccgc aatatactcc ataggcgagc gccggcaacg
    14881 cggccagcat cgtcagcgga ttgccgagca gcaatatccc gcgctgcgcc ccgtcatata
    14941 cctcgtagaa ataccagatc gcgcggctgt tcgccgccca ttgccaccac cgcgacatat
    15001 aggtgtgcgg cgtcgtcacc ccctgttgca gcgatagcat atgcgcctgc cacgatatcg
    15061 ggtcgtgcca ttgcggcggc ggatcggaca gcgcggcgat cgccatgaaa tgcagcagat
    15121 acaccgccac cggcaacagg ccgagccatc ccgccgcctc gatcaacgat acgccgcgca
    15181 ccggccctgc gtcacgcgcg gtcaggatgt gcaaaccccc gcgcccgtcc cgcggcaagg
    15241 cccgccaacg cccccatgca aaggccagcc cggcaaacac gggcagcggc gccgcgttcc
    15301 atttcgccgc caccgccagc cccagcaaca cgccgcccgc acccagccgc acgcgcgccg
    15361 ccgcgacacg cccgctatcg agcgcggcgg cgcatgccca tatccccgcc gcgccaaggc
    15421 ccagcatgta gatgtcgagc atcgcgatcc gcgcctgcac cagcagggtg aaatcggtcg
    15481 cgatcaacac gccggtcgca atcgtcgcga acccgcggtg cgacacgtgc cacaccgcgc
    15541 gcatggccga aaacagcgtc agcatcccga acaccaccga cccgatgcgc cagcccaacg
    15601 catcgtcccc gaacacgccc atgaacagcg cgagcaattg cttgcccagc aacggatgct
    15661 ccgcattgcg tagggtttcg cccgcgatcc agtcgcgcgc ggcgggaagg taatggattt
    15721 cgtcgaagat cggcgtttcg atacgcgcga tatgccacgc cgcgaccacg ccgaacaggg
    15781 ccgtgatcgc gatggcggca gccatggggt cggcgcgatt tacaccccgt gggcgggaac
    15841 gattcatggg gccgatgggt aatggggcat ggcgcgcccg gcaatgcgct tgttgcatcg
    15901 ctcccctctg cccgctaccg gccccgactt atgaaacgtt atactggcac cgaccgctcg
    15961 atcacgcaaa gctggaaacc cgcgacccgc gccgtgcgcg caggcacgat gcggtccgaa
    16021 cacggagaaa cgtcggaggc gctctacctc acctcgggct acagctacga cgatgcggcg
    16081 acccctgcgg cccgctttgc gggcgaggcg gcgggcatga cctattcccg gcttcagaac
    16141 cccaccgtcg ccatgctgga ggaacgcatc gcggtgatgg aaggggccga ggcctgccgc
    16201 acgcaggcat cgggcatggc ggcgatgacc gcggccctgc tgtcgcaatt gtcggcgggc
    16261 gatcatatcg tcgcggcgcg cgcggcgttc ggatcgtgcc gctggctcgt cgattcgcta
    16321 tgcccgcgtt tcgggatcga gagcacgacc atcgattcca ccgacaatga tgcctgggaa
    16381 cgcgcgatcc gccccaatac caaggtgttc ttcttcgaaa cgccggccaa tcccacgctc
    16441 gacatcgtgg accttcgcgc ggtgtgcgac attgcaaggg cgcacggcat caccaccgtc
    16501 gtcgacaatg cgttctgcac ccctgtcatg cagcggccca tcgaatgggg cgccgatgtc
    16561 gtggcctata gcgcgacgaa actgatggag gggcagggcc gcgtcctcgc cggcgcggta
    16621 tgcgggacgg aggagttcat caatgaaacg ctgctcccgt tccaacgcaa caccgggccg
    16681 aacctgtcgc cgttcaacgc atgggtcgtg atgaaggggc tcgaaacgct cgaactgcgc
    16741 gcgcggcagc aatgcgccaa cgcgctcaag gtcgggcaat tcgtcgaaac ccgcgtgccg
    16801 cgcatcctgc accccggtct tgagagccat ccgcgtcaca atctcgcgat gaagcagatg
    16861 gacatgaccg gctgcatctt ctccttcgtg ctcgacggcg ggcgggcgca ggcgcatgcc
    16921 gtgctcgacg ggctggagct gatcgatatc tcgaacaata tcggcgattc gcgctccttg
    16981 atgtgtcatc ccgcctccac cacccatgcc gggctgagtg cggaggcgcg cgccgagatg
    17041 ggcgtggacg aaggcatgat ccgcttcaat gtcgggcttg aggatgcaga cgacattatc
    17101 gccgatctcg accgggcgtt cgaccgggcc ggtttgtgag cctgtcgccc ctcgatgtcg
    17161 aaggccgcga tgcggatggc ggccttcccg ccggctcact cctgtcggcc atcgtcgaag
    17221 gggcggacga tgcgatcatc tcgtgccttc tcgatgggcg ggtgctgtcg tggaaccgcg
    17281 cggcggaacg attgttcggt ttccgcgcgg aggagatgat cgggcaatcg atcgacatgc
    17341 ttatccccga ggaccgcatg gaggaggagg cggacatcat cgcccgcctc gccgcgggcg
    17401 aaacgctgac ctcgtttcag acggtccgcc tgcgcaagga tggcgcgccc ttgtgcgtgt
    17461 cgctcaccac ctcgcccgtg cgcgatgcga gcggcacgat catcggggcg agcaagatca
    17521 tccgcgattc cggatcctgg cacgcggcgc gggatgcgct cgcgcgcagc gagcggcgct
    17581 ttcacatgct cgccgacaat atcgcgcagc ttgcctggat cgcggagccg gacggcgcga
    17641 tccactggta caaccggcgc tggtacgaat ataccggcac gaacgaggag gacatggccg
    17701 gctggggctg gaaagcggtg caccatcccg atcatgtcga gcgggtcgtg cgggaatttc
    17761 gcgcctgcat cgcggccggc acctattggg aggacacgtt ccctttgcgc agcgcggatg
    17821 gggaatatcg ctggttcctg tcgcgcgcga agccggtgca tgatgccgaa ggccggctga
    17881 tgagctggtt cgggaccaat accgacatca ccaatcaacg ggaccaggcc gccgcgatcg
    17941 aaaacctgct gaccgaggtg aaccacaggg tcaagaacac gctggccacg atacaggttc
    18001 tcgcccgccg gtccgcgccc ggccatgacg atttcgtcaa gcgtttcgtc cgccgtatcg
    18061 aggcgctgac catcaatcag gatctgttga tcgaccggcg ctggggcgag gtgccggtcg
    18121 gcgatctggt cgatgcgcag ctgggcttcg ttcgccgccg ggtcggggac cgcctgcgat
    18181 ccgaagggcc ggacgtgctg ctgagcgcgc gcagtgccga aacgctgggc cttgcgttgc
    18241 acgagctggc caccaatgcg ctcaaacacg gggcgctcgc cgatgaagag ggcgaggtgc
    18301 gcgtcatgtt ggaggtggag gacggcgaat tcaccatgcg ctggagcgag gcggggggcc
    18361 cgccggtcaa ggcgcccgat ttcatggggt tcgggtccgc cgtgatccgc gacgtgcccg
    18421 ccgcgacatt cgacggcgaa gcggtgctcg actacacgcc cgaaggtctg tgctggcgcc
    18481 tgacctgtcc gctcgacgcg gtggcggcgc actgaaatcc cgggccgatc gcgcgccaag
    18541 gcggcatgag cggcgttgtg tcgcggcggg atttgggcta tttaccgccg catatgatga
    18601 accggttctt caatcatgtc gcccattcga acggcatcac cgtgcgggtc gcggccaatt
    18661 tcctgcccga acaatcgcgc gtgacggcgg gccgctggtt ctggtcctat cacgtgcgca
    18721 tcgaaaacca tggcgacgaa ccggtgcaat tgctgacgcg gcactggcgc atcaccgatg
    18781 cgaacgggcg cgtctcgctc gtcgatggtg atggcgtcgt cggcgaacag ccgtttctgg
    18841 acccggaaca ggcgcatgat tacgtgtcgg gatgcccgct cgaaacgccg catggcacga
    18901 tggaggggca ttataccttc cgccgcgacg acggcaccat attcgaggcg gcgatcccgt
    18961 tcttcccgct cgacgcgccg acggcgatcc gctgaccgta attcgctggc cctgatccgc
    19021 tggcccggat gacgcgccgg gccggttgca cgcgcctctt gcgccgcggg cccgccgccg
    19081 cctaagaacg gcggcacata cgaacgcgcc gcgagacgag ggcatattga aacgaactca
    19141 cctgccattg aacgggttgc gcgtgctcga cgcggcggcg cggcacctgt cctttacccg
    19201 cgcggcggac gagcttgccg tcacgcccgc cgccgtgggg cagcagattc gcgcgctgga
    19261 ggatctgctc ggcgtggtgt tgttccgccg cacgcccaag gggctggagc tcacggacga
    19321 ggcgcgcgcc gggctcgacc ccttgcgcga agggttcctg cggttcgagg aatcggtgca
    19381 ggcgatgcag tcgggtcaat cgagccattt cttcaccttt gccgcgccgc gcgatttctt
    19441 cggcgcatgg ctggccgcgc ggctcgccgc ctatcgcgcc gaaaatgccg aaacccgttt
    19501 cctcatggca ggcgggcaga acaccgattt cacagaagcg aacctcgatt tcgcggtgcg
    19561 cctcgtcgaa gggccgggcg aactcgaagg ggtgccgctc tcgcccgggc gccgcattgc
    19621 ggtcgcggca ccgggcgccg acgatgcgtg gatcgcatgg cccggccacc ccgcacccga
    19681 aggggtggag ccgggattgc aggtcggcgc cacgggacag gcgctgtcgg ccgcgcttgg
    19741 cgggatgggg cgtgcgctgc tcccgatgca gcttgtcgaa agcgcgctcg ccgacggcac
    19801 gctcgtcgcg gtgggcgaac cggaggagac gcgcgccacc tactggctcg tcgcgccgcg
    19861 cccccaatgg cggcagcgca agatgaaggc gctcgtcgac tatctcaccg ccgcgccgca
    19921 ataggcccgc gccttcggaa cgcaggcggg ccgagcggcg ttaccaccat gcccgccctt
    19981 ccggccgggt cgggagaaac atggcccata tcctttcgat cggcaccgcc gtgccgccgc
    20041 atatcttgcc gcaaagcgac gtcgtcccca tactgaccga tgcgctgggc cacgcaccgc
    20101 cgccgcgcct cgcctccatc ctcaccaaca ccggcatcgc gcaaaggcac atcgcggagg
    20161 acatcggcta ctacttccgc ccccgccggg cgagcgaacg ggccgcgacc ttcgaacggg
    20221 tcgccaccgc attgtgggag gacgcggcgc aggacgcgct cacccgcgcg ggcctgacgc
    20281 cggccgacat cggcaccatc gtcaccgtct gcacgaccgg cacgctcacc ccctcgatcc
    20341 cgagccgcgc gctgcagcgc atgggctttg ctcccaccac gcgcaccgtg ccggtgttcg
    20401 gctggggctg cgcgggcggc gggctgggtc tgtcgctcgc cgcgacgctg gccgatgcgg
    20461 cgcggggtga gggcgcgctg ctcctcgtct gcgtcgaatt gtgcagcctc gcctacgacc
    20521 attcctcgat ggaaaaaaag gatctcgtcg cgctcgccct gttttccgat ggatgcgccg
    20581 ccgcggtcat cgcgccgggc gacggtccca accggctcgg cccgtttgcg caacattgct
    20641 ggccggacac gatcccgatg atgggatggg agatcggcga caccggcttc gacctcgtat
    20701 tgtcgcgcga cattccgcgc ttcgtggaaa aggatttcgc cccgttctgc gacgccttcc
    20761 tcgccgcgca atcgctcacc cgcgcggggc ttgccgaacc ggcctgccat cccggcggcg
    20821 gccgcgtggt ggaggcgctg gccgcgatgt tcgggcgcga cctgcccgcc accgccgccg
    20881 tgctacgcga ttacggcaat atgagcagcc cgaccgtgct cttcatcctg gaccggctgc
    20941 tatccaactc cgcgccgggg ggagagccgg tgctcgtcac cgcgctcggt cccggcttta
    21001 ccggcaccgc ggcgctggtg catcgatgat cgcgcaatgg gcgagctggc cggtatgggc
    21061 atgggccgtg ctcgcctatg tcgttgcctc gcgccttggc gaacttgcct atgcgcggcg
    21121 caatacgcgg cgtctgctgg ccgagggggg gatcgagcat taccccggcc attacccgct
    21181 gttcatcgtg ctgcacggct cgtggctgtt cgccatcctc ctgttcgcgc agcccgcgcc
    21241 cgaaccgtcc tatgcgctgg cctcgctctt cgcgttcagc caggcggcgc gctactgggt
    21301 cctgcattcc atcgggcgct ggtggacgac gcgcatcatt tccgccccgc atttcccgcg
    21361 ggtgcggcgc gggccgtacc gttttttccc gcatcccaat tacgcggtgg tggtggcgga
    21421 gatcgcgctt ctgccgctgc tcctcggcgc gccgtgggtg gcgctggtgt ggtcggtgct
    21481 caacgcgatg ctgcttgccc accgcatccg gctggaggaa aaggcgctct tcttgcgcga
    21541 gggttaggcg gccgtcacgc gcccgcgccg ggggagagga cagcagatgc cgccccgcct
    21601 ccatcctttc gcgcatgagg tcgagcttcg cattgatccg cgcgcgcacc tcgtcctcgt
    21661 cgccgaacgt ctccgcgcgc cattgctgtt tgagcgtttc gtaaacaggg tcgcccggcc
    21721 tcggcatcgc ggcctcgcca tagcggtgcg cacgacgatg gcgcagcatg aacatgacca
    21781 gcgcctcgtt atgccgccgc cattcgccga tgatttcgcc gcccgacacg atgggccgcg
    21841 cctccccctc gatcgcgcgg gtaagcgcgg tatcctcaag cctcgcgatc ccgcaatcga
    21901 ccgcacgctc ccacgcagcg gcgaacccct cggcgccctt gcggctgcgc agcgtataga
    21961 gcgcctcgac actcgccccg atgcgccgcg cggcctgcgt gacgctgccc gtggcggcaa
    22021 gcacggcgat aaagcggcgc tgacgatcgg gcgtgatcga attgcgccgg ggacggggat
    22081 gcacgaacgg cgagaaatcg agcagcggat cgcccggttc cggctcctcg gtggtaaagg
    22141 cgacgtggct cgtccgccgc gaaggccgcg ccgaccggca atgcagcggc gcatcggcat
    22201 aggcctcgcc gatcacgcga taacccgcat ccccgccatc actcttttgg tcgggaacgc
    22261 gcacgatccc ccgccgccgc gcccgccgtg cgtcacgcgc cgtatcgcac agccgcgccc
    22321 ggtcccacgc cgcgcgaaac gcctccgccc cggcgcgata ccgcagcttg tgcagcgccg
    22381 ccacgctaac gccgatctcg gccgcggcat cgccgacgaa cccgcaccgc gcgagcgccg
    22441 cgataaattg ccgctgcgtc tctgcatcca gcttgcgccg tttcttctgc accgccgggg
    22501 taaaggaaag atcgaccatg acacgctccg ccattgatga gggggagcgg ggttaggcgc
    22561 gggcaggggg tgtaggaaaa taaaagtttt tggctgagtt gcatgccact cacgaatgtt
    22621 tgataagtag agcaaagttc aaacgaggcg attgattttc gatctcctat tcagtcagat
    22681 atcaagtctt cgtaagttcg acatttactg atttaaaaga agagcgagct gaagttatcc
    22741 aagccccatg ggaaatggat tgtatcccta ctggaatgga ggcatttgtc gcgtcgaacg
    22801 aagaccaatg gagcggcatc caaaaggtta tcgacgagtc cgattattat gttttaataa
    22861 tagggggaag gtatggcagc ctcacatcgg aaggaattag ctataccgaa aaaaatataa
    22921 atacgcgaaa aactcggggt cccggtatta gcatttgtgc atagacgccc agacgaaata
    22981 ccggcgggta agtccgatat ccagaaggat ttaagagata atctcgaaag atttcgtcaa
    23041 gaattgatgg attcataccc aattaaaaat tgggcgacac ctgctgaact gggtgctggg
    23101 gtatcacgtt cattgatccg cgaaatccgt ataaatacta ggccgggttg gattaggaat
    23161 gatggatctt cacccctaac ccgtcctatt catgaggcta ccgcttcgtg ttgttcggac
    23221 ggcgatgtgg cggtgcctga ttgatcaagg cgcacgcct
//
