LOCUS       NZ_JAIQCI010000001     23228 bp    DNA     linear   CON 28-MAR-2024
DEFINITION  Croceicoccus hydrothermalis strain JLT1
            NODE_1_length_195952_cov_172.613174, whole genome shotgun sequence.
ACCESSION   NZ_JAIQCI010000001
VERSION     NZ_JAIQCI010000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Croceicoccus hydrothermalis
  ORGANISM  Croceicoccus hydrothermalis
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Erythrobacteraceae; Croceicoccus.
REFERENCE   1  (bases 1 to 196036)
  AUTHORS   Chen,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-SEP-2021) State Key Laboratory for Marine
            Environmental Science, Institute of Marine Microbes and Ecospheres,
            Xiamen University, A3-302, Zhoulongquan Building, Xiang'an, Xiamen,
            Fujian 361102, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 2019-11-6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 521.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022378335.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 07:11:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,506
            CDSs (total)                      :: 3,455
            Genes (coding)                    :: 3,380
            CDSs (with protein)               :: 3,380
            Genes (RNA)                       :: 51
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 45
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 30 of 75
            Pseudo Genes (incomplete)         :: 44 of 75
            Pseudo Genes (internal stop)      :: 22 of 75
            Pseudo Genes (multiple problems)  :: 17 of 75
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:29:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 23228
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAIQCI010000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23228
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="lassopeptide"
                     /product="hserlactone"
                     /region_number="1"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /rules="Autoind_synth"
                     /tool="antismash"
     cand_cluster    1..23228
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /detection_rules="Autoind_synth"
                     /kind="neighbouring"
                     /product="lassopeptide"
                     /product="hserlactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..20810
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20810
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[8435:10810](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(8436..10810)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            327..1244
                     /locus_tag="K4G67_RS00005"
     CDS             327..1244
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017183295.1"
                     /locus_tag="K4G67_RS00005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HEPN domain-containing protein"
                     /protein_id="WP_239804374.1"
                     /transl_table=11
                     /translation="MRVDLDHLPEVQQAELARVRETLMTEFSRAISGATQPWKRNGRIL
                     KIILFGSYARDDWVDEPDNGYQSDFDLLIIVNHESLTDIADYWYIAEDKILHDPTVGRP
                     VNIIVHTLQEVNQALERGEYFWVDIVRDGIVVYELPNHALTAPQPLAPTDAYEMAKRYF
                     DEKIVSLGEWIELAEMAFSKGASGSWQNKAAFNFHQATETAYACFLLVRTLYFPRSHNI
                     KFLRSLAEDKEPRLIEAWSRGSRADRRRFELLKRAYVEARYSASYEIGAEDLEAISASV
                     RQLREIVEAVCRDHLDLLRRDAQH"
     misc_feature    1693..1702
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.04"
                     /tool="antismash"
     gene            1739..2302
                     /locus_tag="K4G67_RS00010"
     CDS             1739..2302
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1126:
                     extracytoplasmic-function sigma-70 factor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="K4G67_RS00010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_239804375.1"
                     /transl_table=11
                     /translation="MRMNPAETKRLDAPEADASGKEARQKPDAATLYATEAPRLHRFFR
                     RRTACPDEAQDLVQETFTRVIGHDVPTTLRNPSGYLTRIAQNLLRDRAKVARRRSADLH
                     FSYEGDLPSGTDPVHLLEVRNMLDWLEAAMLELPVTTREVFMAHRLEGLTYAEIAGRSG
                     LTIKQVEKAIARALVVLDRALGPR"
     misc_feature    2593..2607
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     cand_cluster    2608..23228
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="Autoind_synth"
                     /kind="single"
                     /product="hserlactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2608..23228
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[12607:13228](-)"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(12608..13228)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="Autoind_synth"
                     /neighbourhood="10000"
                     /product="hserlactone"
                     /protocluster_number="2"
     gene            2641..3318
                     /locus_tag="K4G67_RS00015"
     CDS             2641..3318
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016648.4"
                     /locus_tag="K4G67_RS00015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FecR domain-containing protein"
                     /protein_id="WP_275588690.1"
                     /transl_table=11
                     /translation="MQDPGPQVTNNNTSVETPRGDIRRMRLPDGSVVTLDSDSRIVVAF
                     TSGERRLRLVAGRARFEVAHEADRPFIVAVGGGEVVATGTRFDVSVIGGKPSVRLIEGS
                     IEVRRPATSAAADTGASMVRLKPGQMALVDTPAPAELAPTAGERWVSGTLSFENAPLAD
                     VLAEANRYATRQVRLGDPSLGSLRFTGGFRAGNPDQLAKALASGFELRIDRGPDGDLVL
                     ARP"
     gene            3460..6369
                     /locus_tag="K4G67_RS00020"
     CDS             3460..6369
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1082:
                     TonB-dependent siderophore receptor family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012801.4"
                     /locus_tag="K4G67_RS00020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TonB-dependent receptor"
                     /protein_id="WP_239804377.1"
                     /transl_table=11
                     /translation="MGVSAVALCMAMPACAQSSEQQHYNLPAQDLSRSVRAVVDQSGAT
                     IVAPADLLAGLRAPALRGEFTPEQALVRLISGTSLRIEHVGNALVLQRDPADVGQDTAA
                     SNAADNEILVTGTRIRGRAPAGAAVTTIDRSDIEQSGYATTQEILQALPQNFGGGPNET
                     TIETNRGNASLNQNYGSGVNLRGLGTGSTLVLLNGERPPMAGFAGVFTDLSMIPTIAIQ
                     RIEVLPDGASALYGSDAVAGVVNIIPRSQFEGIETTARYGLADGFDEIQAGAIGGKRWD
                     TGSIVLAYDYYRRSRLAVADRPYISEDLRRFGGGDYRANYANPGTIVAGGQTFAIPAGQ
                     DGSNLSASDLVAGTQNVQDQWLGADALPFQERHALFAAARQELMPGVEFYAQALFGSRR
                     FDRHLRASSNNALRTVPITNPFYVDPVGTNLPIQVRYNFVEDLGPESLRGKSEALGASS
                     GLRLDVGQWSFDAHATYGTQRENSVFYNRVNTARLAAALADTDPATAYNLLGDGANTDP
                     ATIESIRGSTSDSGRYTMLSGLARADGPLFQLPGGDARLALGGEYRYERFRDRPAISDT
                     TTLTPVELAPTPMPDPRRVTAGYAELLLPLAAPELGLAGLHRLDLSAAVRYEHYSDFGD
                     TTNPKLGLSWQPFESLTLRGTWGTSFRAPTFNDLRPDLATPLQFAIGLTDPASDTGLTY
                     ALILRGTVPDLGPERATSWTAGFDLEPDFMPGLTARLTYFDIDYRDRIASPASETLNFL
                     INRATYASIIDAPADPAIVAAYFSGPGYVALYPITASQVTTIIDSRTQNLASQHLNGFD
                     FDLAYQGKFYDGAFEVGVGGSWLIGFRQALTDDAPEVDILDTLGNPVDLRLRGRASYSG
                     PQFGASLFVNYVDGYENRTGAEPQQVDAWVTVDARISYRLAAEKGPLAGTAIALSASNL
                     FDNDPPFTVNNLGLTTIGYDPENASPQGRVVALQVTKSW"
     gene            6363..8450
                     /locus_tag="K4G67_RS00025"
     CDS             6363..8450
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033523.0"
                     /locus_tag="K4G67_RS00025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Atxe2 family lasso peptide isopeptidase"
                     /protein_id="WP_239804378.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 3.1e-19, bitscore:
                     62.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVMLGALLWATASQFVPPAMSCRERLQPPNGVETPTPRAVTADDI
                     IELRDFGDPWQNPSMDSPFALSPDGRHIAIALRRANVAGNDYCYGIMLISLEDDTWQLL
                     DAGGEPIIMSSDYFGRADKVNGTVTSPPLAWSPDGKWIAYLRRDHGSTQVWRVGVQEKS
                     AQQVTHAAVDVRRFAWSSDGTAIRFTTRPGILDAEAAIMAEGRSGYLFDDRFWPLSADR
                     PLPRETVPYVEQTIDLATGVVSKAQPSSTRPAGKDNAIARPGDPDTLAWLEPEETTAFL
                     TSKRLHASLQGREEVCSAAVCTDVAGFWWDRDGSILFLHDENYAGGGRVTLYRWKPGQS
                     PPVRLWQTDALLIGCALLQSSLVCAEEAADQPRRLVRVAVSDGMITPVFDPNPEWTTIR
                     TGRVEMLNVKSADGAPGFARLVLPPGHRTDERHPLVIVQYTSRGFLRGGTGDEYPIHLL
                     AERGYAVLSFHKPPQPGTEPPSPDLDSFVRRNLAGLAERRRNFTALEAAIDAAISRGVI
                     DPERIAITGLSDGASTVAYALLHSQRYAAAILSTCCDEPSFTQYLSGPAYAAVTEKWGY
                     PGYGEVGFWPDYSLAQDAAKAEPPPILIQASDEEYRMALQTVAALRAARRPVDMYVFPD
                     EMHVKWQPEHRAAIYARGIDWLDYWLRGKMDDDPAKKEQYRRWHALAASGSGRSPVSAR
                     P"
     gene            complement(8436..10148)
                     /locus_tag="K4G67_RS00030"
     CDS             complement(8436..10148)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="K4G67_RS00030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthetase B family protein"
                     /protein_id="WP_239804379.1"
                     /sec_met_domain="Asn_synthase (E-value: 3e-25, bitscore:
                     83.1, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRYVALIGAPPSAIDRAIAAGAEVGMTCVYQLPWLTVIADPDV
                     QVTFLAEMSGVILGEIFTRSFEDGRTAAARIAAVDELPANVWGGYIGFAQAPEGCSVLR
                     GVSGPNPCYFTPLEDGWGFAPDARLLSQITGWSFAIDWHALGSLLLYRESRPEHTCLSA
                     VRELLPGTMATIGAEGLSVRTIWTPARYIAAKIDAFDDASQKLRDTILATIQAWAQQFE
                     RPLLELSGGLDSSIVAAGLATAGSQFRCLSYQASGADLDETDYARCVADHLGASLDKVR
                     PDASAVRLDVSAAAHLPRPLARSFIQETDRLSHEAARRIGADVFFTGNGGDNVFCFLSS
                     IAPVRDRLRTCDIAGSWRTAADVAQVCEVGRWEVLAKTVRRGFRRSAGEEWHWTPDFLA
                     NEVVAGACRPPAHPWLAACEQAAPGSRAHVAAILRIQNYLEGHTRLAYAPLIAPLLSQP
                     VIETCLSIPSWQWCAGGQNRAVARAAFADHLPGDILERQSKGSFVGMISRILELRRDQV
                     RTMLLGGLLAQYRLVDCKAIEQQLAPASPVSGRGAGRILGLVDAEAWARSWSS"
     gene            complement(10124..10810)
                     /locus_tag="K4G67_RS00035"
     CDS             complement(10124..10810)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="K4G67_RS00035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_239804380.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 7.4e-15,
                     bitscore: 48.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF13471 (E-value: 1.3e-21, bitscore: 70.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWRLADHVSFCWVEGQAIFLDLSRDRYFALPRGVNKAFCRWSEQR
                     DPALAMPDVLVRHNLVVSAQLDQMPSVLPCTFAAPTKVATQLNPTGGSRWSRNCEAASL
                     LMRMRRRVRTRPLQQLVAEATLSFGDDIGDRALRRLSVNDLALEFGRVRNWFPKHQISC
                     LPDSLALKTFLARYGHATTLVFGVTAQPFGAHCWVQTGATLLNDVLDHVVRYTPILAQC
                     PAATSH"
     aSDomain        complement(10622..10810)
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_K4G67_RS00035_Lasso_Fused_RRE.1"
                     /evalue="1.10E-15"
                     /identifier="RREFam003.1"
                     /label="K4G67_RS00035"
                     /locus_tag="K4G67_RS00035"
                     /protein_end="63"
                     /protein_start="0"
                     /score="48.4"
                     /tool="antismash"
                     /translation="MWRLADHVSFCWVEGQAIFLDLSRDRYFALPRGVNKAFCRWSEQR
                     DPALAMPDVLVRHNLVVS"
     gene            complement(10869..10997)
                     /locus_tag="K4G67_RS00040"
     CDS             complement(10869..10997)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009823907.1"
                     /locus_tag="K4G67_RS00040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="benenodin family lasso peptide"
                     /protein_id="WP_230291558.1"
                     /transl_table=11
                     /translation="MDTHELHDELVDLGVASVETQGDGLDPFDIGGLQRVAGIGED"
     CDS_motif       complement(10935..10997)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MDTHELHDELVDLGVASVETQ"
                     /locus_tag="K4G67_RS00040_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(10881..10934)
                     /prepeptide="core"
                     /locus_tag="K4G67_RS00040_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="13.30"
                     /molecular_weight="2083.2"
                     /monoisotopic_mass="2082.0"
                     /core_sequence="GDGLDPFDIGGLQRVAG"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MDTHELHDELVDLGVASVETQ"
                     /leader_location="[10934:10997](-)"
                     /tail_sequence="IGED"
                     /tail_location="[10868:10880](-)"
     CDS_motif       complement(10869..10880)
                     /locus_tag="K4G67_RS00040_lassopeptide"
                     /note="tail peptide"
                     /note="lassopeptide"
                     /prepeptide="tail"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     misc_feature    10954..10969
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.07"
                     /tool="antismash"
     gene            complement(11111..11692)
                     /locus_tag="K4G67_RS00045"
     CDS             complement(11111..11692)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012610.4"
                     /locus_tag="K4G67_RS00045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_239804381.1"
                     /transl_table=11
                     /translation="MNAAPVFDRVYGGLKQMLREGRRSPGARLDPAALADELAASITPV
                     RDALYRLTGERMVDAAGEGFQVPLLTEPDLRDLYAWNLQLLLAAPRLVDLPVPQSEETP
                     TSTVAERAEALFAGMARLSGNCEQLAAVTALNDRLHAVRIGEEIWFGDCDEELAALAQA
                     ENRRVLLGRYHRRRIAAVPDLLRLRYRANG"
     gene            complement(11703..12584)
                     /locus_tag="K4G67_RS00050"
     CDS             complement(11703..12584)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014076946.1"
                     /locus_tag="K4G67_RS00050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_239804533.1"
                     /sec_met_domain="PhyH (E-value: 7.6e-29, bitscore: 95.0,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPLSPADHWEVQLLLHGYCAVPDLVPPAQVAALDADLAPQFEE
                     TDFCRGDFYGEHTKRFGRLLTRSEHAAAFVQHPLIIELVERALGAWCDTIQLNLTQAIE
                     IHPGAPQQMPHRDQDMWEGVKGETEYLLNVMWPFTPYTQENGATLVYPGSHGARALDPS
                     EPDMSVTVEMVPGSALIFLGSTLHGAGGNSSEAIRRGMIVSYALGWLKPYENQWLAYPP
                     DVARRFPPELAALVGYRQHRPNLGNWEGLCPSVLLGEGLPDRIGAVDALRPDQAEMVGA
                     FRRSLGRANGGG"
     gene            complement(12608..13228)
                     /locus_tag="K4G67_RS00055"
     CDS             complement(12608..13228)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hserlactone: Autoind_synth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013041121.1"
                     /locus_tag="K4G67_RS00055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-homoserine-lactone synthase"
                     /protein_id="WP_239804382.1"
                     /sec_met_domain="Autoind_synth (E-value: 2.6e-22, bitscore:
                     72.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYLTTLNGTQGVPDGLLAAMFEARKRIFVDMLGWDVPVLAGRYEI
                     DQFDDPRAIYLILSDECGKHLGSARLLETERPHILDTLFPDLCEDAVPKGPTTREITRF
                     ALDPRQNARQRRRVRDTLVCALTNHALASGVEAYTGVAEIAWLQQILAFGWDCEPLGLP
                     REKGASLLGALRIAITHETPMLLASAGLVAEPVATPHTIRHAA"
     gene            complement(13312..14058)
                     /locus_tag="K4G67_RS00060"
     CDS             complement(13312..14058)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1197:
                     autoinducer-binding transcriptional regulator,"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015449333.1"
                     /locus_tag="K4G67_RS00060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="autoinducer binding domain-containing protein"
                     /protein_id="WP_239804383.1"
                     /transl_table=11
                     /translation="MSGLGIAREFFGLAKQASTNADLVQALACISTSMDFDYFALTHHV
                     DFASAEQAGMRLHNYPDDWVAWFDARRLGVSDPVHRASQATSIGFTWQRVPDLIRLTKT
                     DLTVLEHARTSGIGDGFTVPAHVPGEATGSCSFAVAPGRSMPVDNLPLAQLAGAFAFEA
                     ARRINGSRNFDVHTPTLTERQRDCVLWMARGKTDWEIARILGLSQETVTQHLKQARERY
                     DVPKRSVLAVRALFDGLISFSDIFRR"
     misc_feature    complement(14289..14301)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 22.66"
                     /tool="antismash"
     misc_feature    complement(14300..14314)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.4"
                     /tool="antismash"
     gene            complement(14393..15301)
                     /locus_tag="K4G67_RS00065"
     CDS             complement(14393..15301)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007013845.1"
                     /locus_tag="K4G67_RS00065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="toprim domain-containing protein"
                     /protein_id="WP_239804384.1"
                     /transl_table=11
                     /translation="MQQDRSPKVQGARLETSARNIVEQLGGRWSRSRGMCCCPAHADRT
                     PSLSITLGKRAILVHCFAGCTNEAVIEAMAAVGIRIADLFDGTGDPIVAEPRREVANRN
                     ALRLWLEASSLAGSPAEDYLASRGISISSPELRFHPRMPLGPKDAVRFLPAMVAAVRND
                     AGIMALHRSFIDIGKHRLASFAQPKRALGSPGSGAVRFASPDGGRLGLAEGNETTLSAM
                     QLFNIPCWATLGNERFGLATIPESVRQLYLFVDNDAGGRLAEVRAREAYACEGRRIITR
                     RPERAGDDWNDVLMRAVRTSA"
     misc_feature    15362..15378
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    15366..15380
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.87"
                     /tool="antismash"
     gene            15431..16090
                     /locus_tag="K4G67_RS00070"
     CDS             15431..16090
                     /EC_number="4.2.2.n1"
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013832718.1"
                     /locus_tag="K4G67_RS00070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_239804385.1"
                     /transl_table=11
                     /translation="MTRKWAVAAAAATGIGLTVTAHAQEQQSSDGLAAMERTTAGFRVT
                     EGSAGFLLVEHDIWPTQPATAAEMPVADTVPTDLLYRQRHRQGSTPSGFRRASYLPHVH
                     AAEARYALPRGLLDALVWTESRYNPLAVSKAGAAGLGQLMPGTARDLGVSNRFDPVANV
                     FGAAKYLRQMLDKFGVVPLALAAYNAGPGAVDRAGGIPRNGETPAYVREVLRQWRF"
     gene            16078..16311
                     /locus_tag="K4G67_RS00075"
     CDS             16078..16311
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039244.3"
                     /locus_tag="K4G67_RS00075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5818 domain-containing protein"
                     /protein_id="WP_275588684.1"
                     /transl_table=11
                     /translation="MALLNKGVVVSAGRIRISGTLSRGKRGMILTTTDDAWIIECDEIK
                     DDLIGANVTVEGVVAGMNRIHADWIGEESRSS"
     gene            complement(16489..17775)
                     /locus_tag="K4G67_RS00080"
     CDS             complement(16489..17775)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010128014.1"
                     /locus_tag="K4G67_RS00080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="WP_239804387.1"
                     /transl_table=11
                     /translation="MLSELAVRKAKAKEKDYKLADFEGLYLFVAKSGRRSWRLKYRFAG
                     KERRLILGTYPELSLQEARERKLEARRLLADGKDPGIEAKKAAIARTLAKTNTFEIVAR
                     DWFALQEERWSAVHARDVITSLEKEIFPWIGALPVTEIDEPVVLSVLRKIERRGAIETA
                     HRVRQRMSAVFVHAIAEGRSGRDPAAVVGKALKPVPRSRKRPAILSVEGLQDMIRKTEI
                     EFASPLTKLASRFVAMTAQRLGAVRSMSWTELEGIDWEGSEPSTSAIWRIPPGHMKLTS
                     ELKREDTFEHLVPLAPEAVAVLRAVKQLTGRGPLVFPSNRNARIPMSENTLSYFYNRCG
                     YQGRHVPHGWRASFSTIMNEWAERNGTPSDRLVIDLMLAHLPEGVSDSEGVYNRAAFLD
                     RRREIADEWARMIFGIFPSPQKLLEYPSR"
     tRNA            complement(17933..18022)
                     /anticodon=(pos:complement(17986..17988),aa:Ser,seq:cga)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="K4G67_RS00085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Ser"
     gene            complement(17933..18022)
                     /locus_tag="K4G67_RS00085"
     misc_feature    18190..18205
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.87"
                     /tool="antismash"
     gene            18191..18616
                     /gene="hspQ"
                     /locus_tag="K4G67_RS00090"
     CDS             18191..18616
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="hspQ"
                     /inference="COORDINATES: protein motif:HMM:TIGR02097.1"
                     /locus_tag="K4G67_RS00090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="heat shock protein HspQ"
                     /protein_id="WP_239804388.1"
                     /transl_table=11
                     /translation="MSINFGSNEIDTDAGRKRSTFYSPQAGRAVSAPAVTSARFAIGDV
                     VRHRKHDFRGVIFDIDPVFANSEEWYESIPKELRPRREQPYYHLFAENDESSYVAYVSQ
                     QNLTEDGISGPVDHPSIEMIFGEFTDGRYPLHRSLSH"
     gene            complement(18621..19487)
                     /locus_tag="K4G67_RS00095"
     CDS             complement(18621..19487)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011413680.1"
                     /locus_tag="K4G67_RS00095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_239804389.1"
                     /transl_table=11
                     /translation="MNDPKITPAPIKQHVSRFRAPGEPVIGRVNGLGLWTLYMKEVRRF
                     FKVQTQTIWAPAITTLLFLVIFSVALGRSGREILGVNFATFVAPGLIVMGMMQNAFANS
                     SFSLLGGKIQGTIIDYLMPPLSNAELMIAIVGAAITRGVLVGLAVALAMALYPGVDLAA
                     PHPWAIVWFGLMGTAMLAFLGMLTSIWAEKFDHNAAVTNFVVAPLALLSGTFYVIDNLA
                     PFFQSISRLNPFFYVISGFRFGFLGRSDIGDTNMAVLHGAIGLGVLNLVLALIVYAVLR
                     SGWKIRS"
     misc_feature    complement(19534..19543)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            19594..20322
                     /locus_tag="K4G67_RS00100"
     CDS             19594..20322
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006833428.1"
                     /locus_tag="K4G67_RS00100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GcrA family cell cycle regulator"
                     /protein_id="WP_239804390.1"
                     /transl_table=11
                     /translation="MSWTEERIATLTKLWEGGSTASQIAEELGGVSRNAVIGKAHRLGL
                     KSRPSPVKSGEKAKPKPAKPKKETATPEPAAPAAQPVAAKPAPEPAPAPAPAERPVRAE
                     AAPAPAPTPAPAPAASEDDDAPAQKSSPRIVSVGPGGFLRQGPGDQQPPIPPAPPRRLV
                     PAKPSPEIADKTSLLDLSERICRWPMGHPGEPDFHFCGEAVNPGFPYCVEHCGRAYQAQ
                     LPRGSRRPPPPLPFGGPRVR"
     gene            20399..21142
                     /locus_tag="K4G67_RS00105"
     CDS             20399..21142
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010239928.1"
                     /locus_tag="K4G67_RS00105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-2 protease family protein"
                     /protein_id="WP_239804391.1"
                     /sec_met_domain="Peptidase_M50 (E-value: 2.1e-10, bitscore:
                     33.7, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSRHAGLCGFRRYLTGMDETLYLAAALIVPLIIAIVFHEVSHGF
                     VARMLGDHTAEQMGRLTLNPVRHVDPVGTLLVPGVLALLSMPVFGWAKPVPVAKNRLRN
                     PRIGMMLVAIAGPGSNFLLAAIGAVLLGTVVAGAGPDAGGIAGFGLTSLYYFIAINIFL
                     ALFNLLPIPPFDGSHIVEGLLPRRAIPAYERLRPAGFALVLILLLVVPYVFPGLGIVEN
                     VILPPVQWLLAKYIGIADLVAGVRA"
     gene            21139..22104
                     /gene="truB"
                     /locus_tag="K4G67_RS00110"
     CDS             21139..22104
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0004730 - pseudouridylate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011446126.1"
                     /locus_tag="K4G67_RS00110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_239804392.1"
                     /transl_table=11
                     /translation="MTNGWIILDKPLALGSTQAVSAVKRNLREAGLGKVKVGHGGTLDP
                     LATGVLPIALGEATKLAGRMLDATKEYAFTVQFGRETDTLDTEGAVIAESDRRPPFAAI
                     AAVLDHFTGAIDQVPPAYSALKIDGRRAYDRARAGEDVAMASRRVTIHTLTFASERRDD
                     GIAGTFATAGGRPDPYDPAAPLELAESVTLLAKVSKGTYIRSLARDIARALGTYGHVTM
                     LRRTRAGPFAEAQAISLDMLNEIGKGAPLERILLPVEAGLDDIPALSLSPDAAGAVRQG
                     RKLSGLAEPDGTYWAKSGETPVALIEVADGEARVLRGFNL"
     gene            22127..22396
                     /gene="rpsO"
                     /locus_tag="K4G67_RS00115"
     CDS             22127..22396
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017666453.1"
                     /locus_tag="K4G67_RS00115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="30S ribosomal protein S15"
                     /protein_id="WP_239804393.1"
                     /transl_table=11
                     /translation="MSVTAEEKQQIIQDHARHEGDTGSPEVQVAILTQRIRNLTGHFDA
                     NHKDNHSRRGLLVMVNKRRSLLAYLKKIDVERYNDLIKKLGLRK"
     misc_feature    complement(22547..22561)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.71"
                     /tool="antismash"
ORIGIN
        1 ccgcctaaac atcaattccc agacgaggcc caagctccgc taatttacgc agctaggtgt
       61 gccaaatgtt ctgacgacgg acacagctca aacatttacc acgagatagc caatgttctg
      121 gagaaagcct cgggacgctt cccctatcca tatcaggtcg tcaaactgta tccggtcctg
      181 cccgggtggt cggcgctgtg tccaggtgct tgcactaagg gtgccggcgg ttgtttccaa
      241 gcgacttctc aacgcccggg cagggctatc cattgagcag cggagtcttc ggcgatacag
      301 tcagggcatc tgccgacagg acaactatgc gcgtcgacct cgatcatctt cccgaagtac
      361 aacaagcaga acttgcacgc gtccgcgaga cgttgatgac cgaattctcg cgggcgattt
      421 ccggcgcgac ccagccgtgg aagcgcaatg ggcgtatcct caagatcatc ttgttcggca
      481 gctatgcacg cgacgactgg gtcgatgagc cggacaatgg gtatcagtcg gatttcgatt
      541 tgctgatcat cgtcaatcac gaaagcctga ccgacatcgc cgactattgg tacatcgccg
      601 aggacaaaat actgcatgac ccgacggtcg gtcgcccggt caatataatc gtacacacgc
      661 tgcaggaggt taatcaggcg ctcgaacgcg gtgagtattt ttgggtcgat atcgtccgcg
      721 acggaatagt ggtttatgaa ctgccgaacc acgccctgac tgcgccccag ccactagcac
      781 caaccgatgc gtatgagatg gcgaaacggt attttgacga aaaaattgtt tcgttgggcg
      841 aatggatcga actggctgaa atggctttta gcaaaggggc atcgggctca tggcaaaaca
      901 aagctgcctt caattttcat caggctacgg aaacggccta cgcatgcttt ctattggtcc
      961 gcacactcta cttcccccgc tcgcacaata ttaaattcct gcgttctctg gcggaggaca
     1021 aggagccccg gctgatcgag gcgtggtcgc gtggatcgag ggctgaccgc agacggttcg
     1081 agcttttgaa acgcgcctat gtcgaagcac gttattcggc gagttacgaa ataggtgccg
     1141 aggatcttga ggctatctcc gcatcggtga gacagcttcg tgaaatcgtc gaagcggtct
     1201 gccgcgatca cctcgacctg ctgcggcgcg acgcccaaca ttgagtcggc ggtggacaat
     1261 ccgccaaagc ccaacggagc gcagcatcgc tcacgccgtc gttcccgtta accgctcctg
     1321 cgctcgctct gactgaaagg cgaaacagca gttatcactc aactggcgcg agagaccttt
     1381 tattcgctgc acttcaattt gtagcaaccg ctccgcagtt tacttcactt tttatctgaa
     1441 ttgattgtca cagcttgaac tatggcaaag tcggtatagt ctagcgacgc gccgcaatta
     1501 gggcggcgcc gaggcgtgag aacctcgctt gggacaagtc accggttgct ttctgcggcc
     1561 gggtggtcgg cgtgcatgtc caggtcgtgc gcggctaaag gcgtcggcgc gtgttttccc
     1621 aagcacgttc tcatcacccg gctttttaaa ggccgagcct cgcctgcgga ggccggtcga
     1681 tggataaagc tgcaattttt gatgatcggg agggacggcg ttgccgtcca aacctgacat
     1741 gcggatgaac ccggccgaga ccaagcgtct tgacgcgccg gaagcggacg ccagtggcaa
     1801 ggaggctcgg cagaagccgg atgcggcaac gctttatgcc accgaagcgc cgcgcctaca
     1861 tcgttttttc cggcgacgca ccgcctgccc cgacgaagcg caggacctcg tacaggagac
     1921 cttcacccga gtaattggac atgacgtacc aacaacgctc cgtaatccca gcggttatct
     1981 gacccgcatc gcccagaatc ttttgcgtga ccgggcaaaa gtcgcgcggc ggcgttcagc
     2041 cgatctacac ttctcctacg aaggcgacct tccctccggc accgacccgg ttcatctgct
     2101 cgaggtgcgg aacatgcttg actggctcga ggccgccatg ctggagcttc ctgtcaccac
     2161 acgggaggtt ttcatggcgc accgcctcga ggggcttacc tatgccgaga tcgccggccg
     2221 cagcggccta accatcaagc aggtcgagaa ggcgatcgcc cgtgccctgg tcgtactcga
     2281 ccgcgcactg ggcccgcgct gatgccaccg caacagccga aatctgggcc gggcgatgac
     2341 gtgcgcctgg cggccgcaga atggtttgcg cgcatgcgag ggcccgatgc ggaacgtcat
     2401 cgcgccgaat tcgagacctg gtaccgcgcc cattccgctc atgcagccgc ctatgaccga
     2461 atgggactgc gctgggatca aagcggactt gtcggccaca ccccatcagg ccgggcgcga
     2521 caaggcttgc ccgaagcgcc acagcggcgc tttccggtcc gtgcactcgc tctcgtggcc
     2581 tcggccgccg cgatcatagt cgtcgttaca ttgcttcttt cagcgcgcgg caacgtcccc
     2641 atgcaagacc ctggccccca agttacaaac aacaacacgt cggtcgaaac tcccagaggg
     2701 gatatccgac gcatgaggct tcccgatggc tcggtcgtca cgcttgatag cgacagccgc
     2761 attgtcgtcg ccttcacatc tggcgaacgg cgccttcgcc tagttgccgg gcgcgcccgg
     2821 tttgaagtcg cgcatgaggc cgaccggcct tttatcgtcg cagtgggtgg cggcgaggtt
     2881 gttgcgaccg gcacccggtt cgacgtctcg gtgatcgggg gcaagccaag cgtacggctg
     2941 atcgaaggat cgatcgaggt tagaagacca gcaacctcgg cagcggccga tacaggggct
     3001 tccatggtcc ggttaaagcc gggacagatg gcgctggtcg atactcctgc accggccgag
     3061 cttgccccga cggcgggtga gcgctgggtg tcgggaacac tcagcttcga gaatgcaccc
     3121 cttgcggacg tgctcgccga agccaatcgt tacgctaccc gccaggttcg gctcggtgat
     3181 ccctcgctcg gttcgctgcg ctttaccggc ggctttcgtg ccggcaatcc cgaccagctg
     3241 gccaaggcgc tggcctccgg ctttgaactg cgtattgacc ggggcccgga cggcgatctg
     3301 gtgcttgcca ggccctaagg cacaacggct ctccaaaaaa aaaattcgcg cactccgggg
     3361 gaaagccgcg ccgctgtcgt cagacacccc aagcgatccg catggtgcgg gcgctgggga
     3421 gacagcagca tgggacgtgg cggatatcaa ctggttcaga tgggcgtttc ggcggtcgcg
     3481 ttgtgcatgg cgatgccagc ctgcgcacag agcagcgagc agcaacacta taacctgccc
     3541 gcgcaggatc tttcgcgctc ggtgcgcgcc gtcgtcgatc agtcgggcgc gacgatcgtt
     3601 gcgccagccg atctgcttgc gggcctgcgc gcacccgcac tgcgcggtga gttcacgcct
     3661 gaacaggcgc tggttcggct gatctcaggg acgtccctgc ggatcgaaca cgtcggaaat
     3721 gcccttgtgc ttcagcgtga cccggctgac gtcggtcagg acacggcggc atccaatgcc
     3781 gctgacaatg aaattctcgt caccggaacg cgcattcgcg ggcgcgcacc ggcgggcgct
     3841 gccgtcacca cgatcgatcg cagcgatatc gagcagagcg gctatgcgac aacccaagaa
     3901 atcctgcagg cgcttccaca gaatttcggc ggcggcccga atgagaccac catcgagacc
     3961 aatcgcggca atgcctcgct caatcagaat tatgggtccg gggtcaatct ccgcggtctc
     4021 ggcaccggct caacgcttgt cctgctcaat ggagaacgcc ctcccatggc gggtttcgca
     4081 ggcgtcttta ccgatctatc gatgattccc acgatcgcta tccagcgcat cgaagtcctg
     4141 cctgacggcg cctcggcgct atacggatcc gatgcggtag cgggcgttgt caacatcatt
     4201 ccgcgaagtc agttcgaagg gattgagacc accgcgcgct acggacttgc cgatggcttt
     4261 gatgaaattc aggcaggtgc catcggcggc aagcgctggg acactggcag tatcgtactt
     4321 gcctatgatt actaccggcg cagccgcctc gcggtcgcag accgacccta tatcagcgaa
     4381 gatttgcgcc gcttcggcgg cggcgattat cgggccaact atgccaatcc gggcacgatc
     4441 gttgccggcg gccagacctt tgcaattccg gcggggcagg atggtagcaa tctctcggcc
     4501 tccgatctcg tggcgggaac gcaaaacgta caggaccaat ggcttggcgc agacgcgctg
     4561 ccgtttcagg agcgtcatgc gctgttcgcc gccgcgcgcc aggaactcat gccaggcgtg
     4621 gaattttatg cgcaggcatt attcggcagc cggcgatttg acaggcatct gcgtgcctca
     4681 agcaataatg cactacgcac cgtaccgatt accaacccat tctatgtcga cccggttggc
     4741 acgaacctgc cgatccaggt gcgctacaat ttcgtagagg atctcggacc agaatcgctt
     4801 cgcggaaagt cggaagcgct cggcgccagt tcggggcttc ggctcgatgt aggacaatgg
     4861 tcgtttgatg cgcatgcgac ctatggcacg caacgcgaaa actcggtgtt ctataatcgg
     4921 gtcaatacgg cgcgcctcgc cgcggccctc gcggacacgg atcctgcgac agcctataac
     4981 ctgcttggag acggagcgaa caccgacccg gcaacgattg aatcgatccg aggcagcacc
     5041 agcgacagcg ggcgctacac catgctatcg ggacttgcgc gcgccgatgg ccctctattc
     5101 cagctgccag gcggcgatgc ccggctcgcg ctgggaggcg aatatcggta cgaacgattt
     5161 cgggacagac ccgcaatcag cgatacaacg acgctgaccc ccgtcgaact tgcaccgacg
     5221 ccgatgcctg atccgcggag ggtcaccgcc ggctatgccg agcttctgct gccgctggcg
     5281 gctccggaac tcggccttgc gggattacac cggctcgatc tgtcggcggc ggttcgttac
     5341 gagcactaca gcgacttcgg cgatacgacc aatcccaaac tggggctttc ctggcagccc
     5401 tttgaaagcc tgacattgcg cggaacctgg ggcacctcgt ttcgggcgcc gaccttcaat
     5461 gacctgcgcc ccgatcttgc aacaccgctc cagttcgcaa tcggtctcac tgacccggca
     5521 tccgacaccg ggctgaccta tgctctgatc ctgcggggga cggtgcccga tctgggtccg
     5581 gaacgcgcaa ccagctggac cgcaggattt gatctggaac cagatttcat gcccggcctg
     5641 actgcgcggt tgacctattt cgacatcgat tatcgcgaca ggatcgcgag ccccgcttcc
     5701 gaaacgctca actttctcat caaccgggcg acctatgcct cgatcattga tgcgcccgca
     5761 gacccggcga tagtcgcggc ctatttctcg ggaccgggct acgtcgcgtt gtacccgatt
     5821 accgcctccc aggtcacgac gatcatcgat tcgcgtacgc agaacctcgc aagccagcat
     5881 ctcaacggct ttgatttcga tctcgcctat cagggcaagt tttacgacgg tgcgtttgaa
     5941 gtgggcgtag gcggcagttg gctgatcgga ttccgccagg cgctgaccga cgacgcaccg
     6001 gaagtcgaca ttctggatac gctcggcaac cctgtcgatc tgcgtctccg cggccgcgcg
     6061 agctattccg gcccgcaatt cggcgcgtca ctgttcgtga actatgtcga tggctatgag
     6121 aaccgtacag gcgcggagcc gcaacaggtc gatgcctggg tcaccgtgga cgctcggatc
     6181 agctaccggc ttgctgcaga aaaaggcccg cttgccggga cggccattgc cctgagcgcg
     6241 agcaatctgt ttgacaatga tccaccgttc acggtcaata atctcgggct gacgacgatc
     6301 ggctacgatc cggagaatgc cagccctcaa ggacgggtcg tcgcgctaca ggtgaccaaa
     6361 tcatggtgat gctgggagcc cttctttggg caacggcaag ccagttcgta ccgccggcca
     6421 tgtcctgccg cgagcgatta cagccaccaa acggtgtaga gacgcccacg ccacgcgcag
     6481 tgacggcgga cgacatcatc gaattgcgcg acttcgggga tccctggcag aatccgtcga
     6541 tggacagccc tttcgcgctt tcgccggacg ggcgccacat tgccattgcg ctgcgccgcg
     6601 ccaacgtcgc gggtaatgac tattgctatg gcatcatgct tatttcgctc gaagatgaca
     6661 catggcagct cctcgacgca ggcggcgaac cgataatcat gagcagcgat tatttcggac
     6721 gagccgacaa agtaaacggg accgtgacca gtccgccgct tgcctggtcg cccgatggca
     6781 agtggatcgc ctatttgcgg cgcgatcatg gaagcaccca agtctggcgg gtgggggtgc
     6841 aggaaaagtc agcgcaacag gttacgcatg cggcagtcga tgtccgtcgc ttcgcctggt
     6901 catccgacgg tactgccatc cgcttcacga cccgtcccgg catattggac gcggaagccg
     6961 ccatcatggc ggaaggccga agcggctatc tctttgatga tcgcttctgg ccgctaagcg
     7021 cggaccgacc tcttccgcgg gaaactgtgc cgtatgtcga gcaaaccatc gacctcgcaa
     7081 cgggagtggt gagcaaggct cagccttcgt ccacgcgccc tgcgggcaag gacaatgcca
     7141 ttgcccggcc cggcgatccg gacacgctgg cctggctcga gcccgaagag acaacggcat
     7201 ttctgacttc caaacgcctc cacgccagtt tgcaagggcg cgaggaggtc tgttcggcag
     7261 cggtctgcac cgatgttgcc ggtttttggt gggaccgcga cggcagtatt cttttccttc
     7321 atgacgaaaa ttatgccggt ggcgggcggg tgaccctcta ccgatggaaa cccggccaat
     7381 cgccgccagt gcggttatgg cagaccgatg cgctcctgat cggctgcgca cttctccagt
     7441 cttcactggt ttgcgccgag gaagctgccg accagccacg gaggctcgtg cgggttgcag
     7501 tcagcgacgg catgataacc ccggtatttg atccaaatcc cgaatggacc accatccgca
     7561 ccgggcgggt cgaaatgctc aatgtcaaat cggctgacgg cgcgcccggc ttcgcccgtc
     7621 tcgtcctgcc gcccgggcat cggaccgacg aacgccatcc gctggtcatc gttcaataca
     7681 ccagccgtgg atttctgcgt ggcgggacgg gcgatgaata tccgatacat ttgcttgcag
     7741 aacgcggcta tgccgtgctg agcttccata agccgccgca accggggacg gagccgccct
     7801 cacccgatct cgatagcttc gtgcgccgca accttgccgg gcttgccgag cggcgccgca
     7861 atttcaccgc gctggaagcc gcgatcgatg ccgccatttc gcgcggcgta atcgatcccg
     7921 agcgcatcgc gatcactggc ctaagcgacg gcgcaagtac ggttgcatat gcgctcctcc
     7981 acagccagcg atatgcagcg gcgatcctca gcacctgctg tgatgaaccg agtttcaccc
     8041 agtatctgtc ggggcccgct tatgcggcag tcaccgagaa atggggatat ccgggctatg
     8101 gtgaggtagg cttctggccc gactattcgc tggcgcaaga cgcggcgaaa gctgaacccc
     8161 cgcccatcct cattcaggct tccgatgaag aatatcgcat ggcgttacag actgtagcag
     8221 cgcttcgcgc cgcgcggcga ccggtcgaca tgtatgtctt tcccgacgaa atgcatgtga
     8281 aatggcagcc cgaacatcgc gcggcgatct atgcaagggg tatcgactgg ctcgactact
     8341 ggttgcgcgg caaaatggat gacgaccctg ccaagaaaga acagtatcgc cgctggcatg
     8401 cgcttgcggc cagcggtagc ggccgcagcc cggtttcagc tcgaccatga gcgcgcccag
     8461 gcttcagcat cgacaagacc gagaatgcgg cccgcgccac gccccgagac cggcgatgcc
     8521 ggagcaagtt gctgctcgat cgccttgcaa tcgaccagcc tgtattgggc cagcaaaccg
     8581 ccgagcagca tcgtgcggac ctgatctctg cgcaattcga ggatacgtga aatcattccc
     8641 acaaagcttc ccttgctttg ccgctcaaga atgtcgccgg ggagatgatc cgcgaaggcg
     8701 gcccgggcaa ccgcgcgatt ttggccgccc gcgcaccact gccagcttgg aatcgacagg
     8761 caggtttcga tgacgggttg cgagagcaga ggtgcgatga gcggtgcata tgcgagccgt
     8821 gtatgtcctt caaggtaatt ttgaatgcgc aggattgcag ccacatgcgc gcggcttccc
     8881 ggcgcggctt gttcgcaagc cgcaagccaa ggatgcgcag gcggccgaca cgctcctgca
     8941 accacctcat tggcgagaaa gtcgggggtc cagtgccact cctcccctgc cgaccgccga
     9001 aacccccgcc gtacggtttt ggcgagaacc tcccaccgtc caacctcgca aacctgtgcg
     9061 acatccgccg cggttcgcca gcttcccgcg atgtcgcacg ttcgcaggcg gtcgcgtacc
     9121 ggtgcaatcg aggacaagaa gcaaaagaca ttgtcgccgc cattgccggt aaaaaagaca
     9181 tcggctccga tgcgccttgc agcctcgtgg ctcagacgat cggtttcctg aatgaagctc
     9241 ctcgcaaggg ggcgtggcag atgtgctgca gccgacacgt cgagccgcac cgcgcttgca
     9301 tccggacgca ccttgtcgag cgatgcgccc agatgatcgg cgacacagcg cgcatagtca
     9361 gtttcgtcga ggtccgcgcc cgacgcctgg taactgaggc aacgaaactg gctaccggcc
     9421 gtcgcaagtc ctgcagcaac gatgctcgaa tccagccctc cggacagttc gagtagcggt
     9481 cgttcgaatt gctgcgccca tgcctggatc gtcgcgagaa tagtgtcgcg aagcttttgc
     9541 gatgcgtcgt caaacgcgtc gatttttgcc gcaatatacc gcgcaggtgt ccatatcgtc
     9601 ctgacgctca agccctcggc gcctatcgtg gccatcgtcc cgggcaacaa ttcgcgaacg
     9661 gcactcagac acgtgtgctc ggggcgcgat tctcgataga gcaacagact gccgagagcg
     9721 tgccaatcga ttgcgaagct ccacccagtg atctgtgaaa gcagtctagc atcgggcgca
     9781 aagccccagc catcttcaag cggcgtgaaa tagcagggat taggaccgga tacgccgcga
     9841 aggacggagc aaccctccgg agcctgcgcg aagccaatat agcctcccca gacattggca
     9901 ggaagttcat ccacggctgc gatccgggcg gcggcggtcc tgccgtcttc aaaggagcgg
     9961 gtaaagattt caccgaggat gacgccagac atttccgcaa ggaaggtcac ctggacatct
    10021 gggtctgcaa ttaccgtaag ccagggcaac tgatacacgc atgtcattcc cacttccgca
    10081 ccggcggcga tcgccctgtc gatcgccgaa ggcggggcgc cgatcaatgc gacgtagcgg
    10141 cgggacattg tgcaaggatc ggggtgtatc ggacgacatg atcgagcacg tcattgagaa
    10201 gcgtcgcacc cgtctggacc cagcaatgtg cgccgaacgg ctgcgcagtg accccgaaaa
    10261 cgagtgtcgt cgcgtgacca taccgagcga gaaaggtctt caatgccaga gagtcgggca
    10321 ggcacgatat ctgatgcttg ggaaaccagt tacgaacgcg cccaaattca agcgccaaat
    10381 cattgacgga caatcgccgc agcgcccgat ctccaatgtc atcgccaaat gataatgtcg
    10441 cttcggcaac gagttgctgt aacggccggg ttcggacgcg gcgacgcata cgcatcaaca
    10501 gcgaggccgc ttcacagttc cgcgaccatc gcgatccgcc cgtcgggttc agctgggtgg
    10561 caaccttggt gggagctgcg aatgtgcaag gcagcacaga aggcatttga tccagttgtg
    10621 cagacaccac cagattatgg cgaacaagga catcgggcat cgcaagcgcg gggtcacgct
    10681 gctctgacca tcggcagaac gccttgttca cgccgcgggg gagcgcaaaa tagcgatcac
    10741 gcgacaggtc cagaaagatg gcctggccct cgacccaaca gaagctgaca tgatcagcga
    10801 gacgccacat gaaatagcct tacgcaaagg ctggcgcgcc atagggcgcg ccagcgatat
    10861 cgggttcgtc aatcttcgcc gatgccggcg acgcgctgca ggccgccaat atcgaacgga
    10921 tcgagaccat caccctgcgt ctcgacgctt gcgacgccga gatcgaccag ttcgtcgtga
    10981 agttcatgcg tgtccatgat catctccttt gttccaccgc gatcagtcgc ggcagtccaa
    11041 gtgtccggac ctcgcctcca aatcccaagt ttatatggcg cgtatttgaa ggaagttcag
    11101 gggcaatatc tcagccattc gcgcgatagc gcaggcgcag aaggtcgggc accgcagcaa
    11161 ttcgccgccg atgatagcgc ccgagcagca cccggcggtt ttcggcctgc gccaaggcgg
    11221 cgagttcttc atcgcaatca ccgaaccaga tttcttcacc gatccgcacc gcatgcaacc
    11281 ggtcgttgag cgcagtaaca gcagcgagtt gttcgcaatt ccctgacagc cgcgccattc
    11341 cagcaaagag cgcttcggcg cgctcggcga ccgtactcgt cggagtctcc tcactttgcg
    11401 gcaccggcag atcgacaaga cgcggggcgg cgagcagcag ttgcaggttc caggcataaa
    11461 gatcgcgaag gtcaggttca gtaagcaagg gcacctggaa gccctcgccc gctgcatcaa
    11521 ccatgcgctc gccggtgagc cggtagagcg catcgcgtac cggggtgatg ctggcagcga
    11581 gctcgtcggc aagcgcggcg ggatcgagac gggcgccggg tgatctgcgg ccttcccgca
    11641 gcatctgctt caggcctcca tagacccgat cgaacaccgg cgccgcattc atcacaaagc
    11701 gctcagcccc cgccgtttgc gcgaccgagg ctgcggcgga acgcgccgac catttccgcc
    11761 tggtcgggcc gtaacgcgtc gaccgcgccg atcctgtcgg gaaggccctc gcccagcaga
    11821 accgaagggc acaggccttc ccaattgccg agattggggc gatgctggcg ataacccacc
    11881 agcgcagcga gctcgggcgg gaagcgccgt gcgacgtcag gtggataggc gagccactga
    11941 ttttcatagg gcttgagcca cccgagggca taagagacga tcatcccccg gcggatcgct
    12001 tcgctgctat tgccgccggc accgtgcaag gtcgatccca gaaagatcag ggccgagcct
    12061 ggcaccatct cgacagtgac gctcatatcc ggttcgctgg gatcaagtgc gcgtgcgcca
    12121 tgactgcccg gatagacgag cgtcgcgcca ttctcctgcg tatagggcgt gaatggccac
    12181 attacattga gcagatattc cgtctcgccc ttcacccctt cccacatatc ctggtcacga
    12241 tgcggcattt gctgcggggc gccggggtga atttctatgg cctgggtaag gttgagctgg
    12301 atcgtatcgc accacgcacc aagcgcacgt tcgacaagct cgatgatgag cggatgctgg
    12361 acgaacgcgg cggcgtgctc cgagcgtgtc agcaaccggc caaagcgttt ggtatgctcg
    12421 ccgtaaaagt ccccgcgaca gaaatcggtc tcctcgaatt gcggcgcgag atcggcgtcg
    12481 agcgccgcca cctgcgcggg cgggacgaga tcgggcacgg cgcaatagcc gtgcaatagg
    12541 agctgcacct cccagtgatc ggcgggggag agcgggagtt gcatctgcgt tgccatagtc
    12601 ctcaccctca ggctgcgtgg cggatagtgt gcggcgtggc aaccggctcc gcaacaagcc
    12661 cggcactggc gagcagcatc ggcgtttcat gagtgatcgc gatccgcagc gccccgagaa
    12721 ggctcgcgcc tttctcgcgc ggcaatccga gcggttcgca gtcccagcca aaggcaagta
    12781 tctgctgcag ccatgcgatc tcggcgacgc cggtataggc ctcgacgcca cttgccagcg
    12841 catgattggt cagtgcgcag accagtgtgt cgcggacccg gcggcgctgg cgggcattct
    12901 ggcgtgggtc cagggcaaaa cgggtgatct cccgggtcgt cggccctttt ggcaccgcgt
    12961 cctcgcaaag atcgggaaaa agcgtatcga ggatatgcgg gcgctcggtt tcaagcagcc
    13021 gtgccgaccc gagatgcttg ccgcactcat cggagaggat gagatatata gcgcgcggat
    13081 catcgaactg atcgatttcg tagcgcccgg cgagcaccgg gacgtcccag ccgagcatgt
    13141 cgacgaagat acgcttgcgc gcctcgaaca ttgcagcgag aaggccgtcg ggcacaccct
    13201 gcgtgccatt aagggtcgtc aaatacatga tggtcgctcc cgtctgatgg acgggtgacc
    13261 ctcaccccgg cggtgatttt cgcctatccc cagttctggg gatagtgcgt tctagcgtcg
    13321 gaagatgtcg ctgaaagaaa tcagtccgtc gaacaaggcg cgcactgcca gcacagaacg
    13381 cttaggcacg tcgtagcgtt cacgcgcctg tttgagatgc tgagtgaccg tttcctggct
    13441 caggcccaga atccgtgcaa tctcccagtc ggtcttgccg cgcgccatcc acaggacgca
    13501 gtcgcgttgg cgttcagtaa gtgtcggcgt gtggacatcg aaatttctcg agccgttgat
    13561 ccggcgcgcc gcttcaaacg cgaaggcgcc ggccaattgc gccagcggca aattgtcgac
    13621 cggcatggat cgcccgggtg ccactgcgaa tgagcaggat ccggttgctt ctcccgggac
    13681 atgggcaggg accgtgaaac cgtcgccaat cccgcttgtg cgcgcatgtt cgagtacagt
    13741 gaggtcggtt ttggtgaggc ggatgagatc gggcacccgc tgccaggtga aaccgatact
    13801 cgttgcctgg ctggcgcgat gcacgggatc gctcactccc agacgccgcg cgtcgaacca
    13861 ggcgacccag tcgtccggat agttatggag ccgcatcccc gcttgttccg ctgacgcaaa
    13921 gtcgacatga tgcgtcagcg cgaagtaatc gaaatccatg ctggttgaaa tacaggccag
    13981 cgcttgcacg agatcggcgt tcgtcgacgc ctgttttgcc aggccgaaaa actccctggc
    14041 tattcccaat ccgctcatcg tccgcatcga tcgagggggc gtttcccaat tcgccggatc
    14101 ccgcaaatcg ccttttatgg gccgggcggc ctcggtctca tgtcgcgccc ccgaacctgc
    14161 tgtaccgcct ccttccgggc atcccgtttc aaccgctctc caatcgacgg gaaagcgccg
    14221 cgctcccatg cagcttgtgc ttgtggcatc ctattggaga tgccgaacaa ctatttggct
    14281 tcagcccatt ccaaaatgca aatttttgag aattactcgc ggcaattttt caactcccat
    14341 gattgctgct ccgtgttcgg atccgtggaa catcgccagt aggggccgct cttcatgccg
    14401 aagttcggac cgcgcgcatg agcacatcgt tccagtcgtc cccggctcgc tctggccgcc
    14461 gggtaataat ccgccgacct tcgcaggcat acgcctcgcg agctcgcact tcggcaaggc
    14521 gcccgcccgc atcattgtcg acaaagagat acagctgccg caccgattcc gggattgtgg
    14581 ccaggccgaa gcgttcattg ccaagcgttg cccagcaggg aatgttaaac agctgcatcg
    14641 ctgagagagt cgtttcgttt ccttctgcga ggccgaggcg tcctccatcc ggacttgcga
    14701 aacgaactgc accagaaccg gggctgccca gcgcgcgttt gggctgggca aatgatgcca
    14761 ggcggtgctt gccaatatcg atgaaggacc ggtgcagcgc cattataccg gcatcattgc
    14821 ggacagccgc caccatcgcg ggcagaaagc ggacagcatc ctttggcccc aatggcatgc
    14881 gtggatggaa gcgcagctct ggcgacgata tgctgatacc tctggacgcg agatagtcct
    14941 ccgcggggct cccggccagg gaagatgcct cgagccaaag cctgagagca ttgcgattgg
    15001 cgacctcccg tcgtggctcg gccacgatcg gatcacctgt gccatcgaac agatccgcaa
    15061 tccgtatccc aaccgcggcc atggcttcga taaccgcctc gttcgtgcag ccggcaaagc
    15121 aatggacaag gatggcccgt ttgccgagcg tgatgctgag cgaaggagta cgatcggcat
    15181 gcgccgggca gcagcacatg ccacgcgacc gagaccatct gccacccagt tgttcgacga
    15241 tgttgcgggc gctggtttcc agtcgtgcgc cttggacttt gggtgaccgg tcttgttgca
    15301 cgggggcatc tccatcgtaa catgccttca cccgcgcagc ctccgctctg cgtcgcttgg
    15361 gattcaattt tcctacaatg atcgttctat atatgttcca tatcgattcg gctattgagg
    15421 aaatcggtca atgacacgga aatgggcagt ggccgctgca gcagcgaccg gaattgggct
    15481 caccgtgact gctcacgcgc aggaacagca gtcctctgac gggcttgccg cgatggaacg
    15541 cacaaccgcc gggttccgcg tcacggaagg gtcagccggc tttctgcttg tcgagcatga
    15601 catttggccc acgcagccag cgaccgcagc agagatgccg gttgccgaca cagtaccaac
    15661 cgatttgctc tatagacaac gacaccgcca aggcagcacg ccgtccggct tccgccgcgc
    15721 aagctacctc ccccatgttc acgctgcaga ggcccgatac gcactgccac gcggtcttct
    15781 cgatgcgctt gtttggacag agtcccgcta caatccattg gccgtcagca aagcgggcgc
    15841 tgccgggcta ggacaattga tgcccgggac ggcgcgcgac cttggtgtat ccaaccgctt
    15901 cgatccagtt gccaacgtct tcggcgcggc taaatacctt cgacagatgc tcgacaagtt
    15961 tggcgtagtt ccgctagcgc tcgccgctta caatgcaggt ccgggcgccg ttgatcgcgc
    16021 gggtggcatt ccgcgcaatg gcgagacgcc agcctatgtg cgcgaagtgc tgcgccaatg
    16081 gcgcttttga acaagggggt agtagtgagc gccggtcgaa tacgcatctc gggaacgctg
    16141 agccgcggga agcgcggaat gatcctgaca acaacagacg atgcctggat catcgaatgc
    16201 gacgagatca aggacgacct tatcggcgct aacgtcaccg ttgagggcgt tgtcgcaggc
    16261 atgaaccgta tccatgcaga ctggattggc gaagaatcgc ggtcatcctg attcaaacag
    16321 ttgtgtctta gcgaatggga agggtcgctc cattcccaat gccagtacga aacttgcatg
    16381 gctccccgcg taaatgagac ttcaaacgaa acttccgcgg gtcagtgccg atcgtcaccg
    16441 gaagcccgat ccgaacgatc gatccacttc cgataagggt aggaccggct atcttgaagg
    16501 atattccaat agcttctgcg gcgatggaaa aatgccgaat atcattcgcg cccattcgtc
    16561 ggctatctct cgccgacggt cgagaaatgc cgctcgattg taaacgcctt cggagtccga
    16621 aacgccttcg ggtaaatgcg ccagcatgag atcgatcacc agtcgatcac tcggagtacc
    16681 gtttcgttcg gcccattcgt tcataattgt tgagaatgat gctcgccagc catgcgggac
    16741 atgcctgccc tggtatccac agcgattgta gaaatagctc aaggtattct cgctcattgg
    16801 aatgcgggca ttcctgttgc tgggaaagac cagtggtcca cggccggtaa gctgctttac
    16861 ggctcgcagg accgcgaccg cctcaggcgc tagcggcaca agatgttcga aagtatcttc
    16921 tcgtttcagc tcactcgtaa gcttcatatg accgggagga attcgccaga tcgcagaggt
    16981 ggagggttct gagccttccc aatcgatgcc ctccagttcg gtccacgaca tcgaccgcac
    17041 ggccccaaga cgctgggccg tcatcgcaac aaatctcgaa gcaagcttgg tgagcggtga
    17101 ggcaaattcg atctccgttt tacggatcat atcctgcaag ccttccacgc tgagaatggc
    17161 ggggcgcttg cggctacgcg gtaccggctt gagggctttt ccaacgacgg ctgctggatc
    17221 tctgcctgat cgaccctcgg caattgcgtg cacaaagacg gcagacatcc tctgccggac
    17281 gcgatgggcg gtctcaattg cgccacgacg ctcaattttt cgaagcaccg aaagaaccac
    17341 cggctcatcg atttctgtca ctggcagcgc accgatccac gggaatattt ccttctcgag
    17401 gctagtgatc acatccctcg catggacggc agaccaacgc tcctcctgca gagcaaacca
    17461 gtccctggcc acaatctcga aagtatttgt tttagccaaa gtccgagcaa tggcagcctt
    17521 cttggcttcg atgccgggat ctttcccatc tgccaacagc ctgcgcgcct ctagcttacg
    17581 ctcgcgagcc tcctgcaagg aaagttcggg ataggtcccc aaaatgagcc tacgctcctt
    17641 tcccgcaaac cgatatttca accgccaact gcgacgaccg gatttagcga caaataggta
    17701 cagcccctcg aaatcagcga gtttgtaatc cttctctttc gccttcgcct tccgcactgc
    17761 aagttcgctg agcatctgtg cccccaattt tgcaattcga tgcccccaaa tgtgccccca
    17821 aatgtggcgg atccctatgg aaaaatcgaa acaaatagag aacacaaact agccgaaaat
    17881 ggccaaaaat caaggaaaac cgtgggtttc cggacgcttg aggaagggtg actggcggag
    17941 agggtgggat tcgaacccac ggtacggttg cccgtacact gcatttcgag tgcagcgcat
    18001 tcgacctctc tgccacctct ccgcatccga ggttcgtgca tcgcctttcg gcaacgggtc
    18061 gaacgaaggc gggcggttaa ccgatgcgcc gccctttgcc aagagggcat tcgcaattta
    18121 ttcgcgtttt cctacatgcg cgaaatggcg ctcgcttgtt tcgatcccgc catgcgccta
    18181 tattggcggc atgagcatca atttcggttc caatgagatc gacacggacg cgggcaggaa
    18241 acgctccacg ttctattccc cgcaggccgg acgggcggtc agcgcccctg cggtgacgag
    18301 cgcgcgattc gccatcggcg acgtcgtccg ccaccgcaag cacgatttcc gcggcgttat
    18361 cttcgatatc gaccccgtct tcgccaatag cgaggagtgg tacgaatcca ttcccaagga
    18421 actgcgcccg cggcgcgaac aaccctatta ccacctgttc gcggaaaacg acgaaagcag
    18481 ctatgtcgcc tatgtcagtc agcagaacct gaccgaggac ggcatttcag ggccggtcga
    18541 tcacccctcg atcgagatga tcttcggcga attcaccgac ggccgctacc cgctgcaccg
    18601 ctcgctcagc cattgatcgg tcagctgcgg atcttccatc ccgaccgcag caccgcatag
    18661 acgatgagcg cgagcacgag gttgagcacg ccgagcccga tggccccgtg aaggaccgcc
    18721 atgttcgtat cgccgatgtc gctgcgcccc agaaagccga agcgaaagcc tgaaatcacg
    18781 tagaagaacg ggttcagccg gctgatcgac tgaaagaacg gggcgagatt gtcgatgaca
    18841 tagaacgtgc ccgacagcag cgcgagcggt gccaccacga aattcgtgac cgccgcgtta
    18901 tggtcgaact tttccgccca gatcgacgtc agcatgccga ggaacgccag catcgcggtt
    18961 cccatcaaac cgaaccacac gatcgcccac gggtgcggcg cggcaaggtc gacaccggga
    19021 tagagcgcca tcgcgagcgc cacggccagc ccgaccagca cgccgcgcgt tatcgccgcg
    19081 ccgacgatgg cgatcatcag ctccgcattg gacaagggcg gcatgagata gtcgatgatc
    19141 gtgccctgta tcttcccgcc aagcaggctg aagctggaat tggcgaaggc attctgcatc
    19201 atgcccatca cgatgaggcc aggcgcgacg aaagtggcga aattcacgcc gaggatttcg
    19261 cgccccgacc ggcccagcgc gaccgagaag atgacgagga acaggagcgt cgtgatcgcc
    19321 ggcgcccaga ttgtctgcgt ctgcaccttg aagaaacggc ggacctcttt catatagagc
    19381 gtccacagcc cgagtccgtt gacacggccg ataacaggct cacccggcgc gcgaaagcgc
    19441 gagacatgtt gctttatcgg ggcgggcgtg attttcggat cgttcataca gtcggtgcgg
    19501 ttaccggtat gcgaaaggga tggcaagcag ccccgccgcc ttccacgccg cgtccgcacc
    19561 ctgtcgggcg aaaagttttt gaacggagta tccatgagct ggaccgagga acgcatcgcc
    19621 acgctgacaa agctgtggga gggcggatcg accgcatcgc agatcgcaga ggaactgggc
    19681 ggtgtgagcc gcaacgcggt cattggcaaa gcgcatcggc tgggcctgaa atcgcggcct
    19741 tcgcccgtga aatccggcga aaaggcgaag cccaaaccgg ccaagccgaa gaaggagacc
    19801 gcaacgcccg aacccgcggc accggccgcg caaccggtcg cggcgaaacc tgcgccggaa
    19861 cccgcgcccg ccccggcacc cgcggaacgc cccgtccgcg cggaggccgc gcccgccccg
    19921 gccccgaccc ccgccccggc ccccgcagcg agcgaggacg acgacgcacc cgcgcagaaa
    19981 agcagcccgc gcatcgtgtc ggtcggcccc ggcggcttcc tgcgtcaggg tccgggcgat
    20041 cagcagccgc cgattccccc cgcgccgccg cgccggctcg tccctgcaaa gcccagcccg
    20101 gaaattgcgg acaagacaag ccttctcgac cttagcgagc ggatctgccg ctggcccatg
    20161 ggacatccgg gcgaaccgga tttccatttc tgcggcgagg cggtcaatcc cggcttcccc
    20221 tattgtgtcg aacattgcgg ccgcgcgtat caggcgcaat tgccgcgcgg ttcgcgccgt
    20281 cccccgccgc cgctgccgtt cggcggtccg cgcgtgcgtt gaaatcccgc tgaattcgtg
    20341 aaagagggcg tccgggccga ccgggcgcct ttttttatgg cgggtctttt tatcgcccat
    20401 gaccagtcgc catgctggcc tttgcgggtt tcgtcgctat ctgacgggca tggacgaaac
    20461 cctctatctt gccgcggcgc tgatcgttcc gctcatcatc gccatcgtct ttcacgaggt
    20521 gtcgcacggc ttcgtcgcgc gcatgctggg cgatcatacg gcggaacaga tggggcgcct
    20581 cacgctcaat cccgttcgcc atgtcgatcc ggtcggtacg ctgctggtgc cgggcgtgct
    20641 ggcattgttg tcgatgccgg tgttcggatg ggcaaagccc gttccggtgg caaagaaccg
    20701 cctgcgcaat ccgcgcatcg gcatgatgct cgtcgcgatc gccgggccgg ggagcaattt
    20761 cctgctggcc gctatcggtg cggtgctgct gggcacggtt gtggcggggg ccgggccgga
    20821 tgcggggggc atcgccggtt ttggcctgac gtcgctttat tatttcatcg ccatcaacat
    20881 tttcctcgcg ctgttcaatc ttctgcccat cccgcccttc gacgggtcgc atatcgtgga
    20941 agggctgctc ccgcgccggg cgatcccggc ctatgagcgg ctgcgtccgg caggttttgc
    21001 gctggtgctg atcctgttgc tcgtggtgcc ctatgtattc ccggggcttg gcatcgtgga
    21061 aaatgtcatc ctgccgccgg tgcaatggct gcttgccaaa tatatcggca tcgcggacct
    21121 cgtcgccggg gtccgcgcgt gacgaacggg tggatcatcc tcgacaagcc gctcgcactc
    21181 ggatcgacgc aggcggtttc ggcggtgaag cgcaatttgc gcgaggcggg gctgggcaag
    21241 gtaaaggtgg gccatggcgg cacgctcgac ccgctggcga ccggtgtcct gccgatcgca
    21301 ttgggcgagg cgacgaagct tgcaggccgg atgctcgacg cgacgaagga atatgccttt
    21361 accgtgcagt tcgggcgcga gaccgacacg ctcgacacag aaggcgcggt gattgccgaa
    21421 agtgaccggc gcccgccgtt cgctgcgatc gcggccgtgc tcgaccattt caccggtgcg
    21481 atcgatcagg tcccgccggc ctattccgcg ctcaagatcg atggtcggcg cgcctatgac
    21541 cgtgcgcgcg cgggggagga cgtggcgatg gcgtcgcgcc gcgtcacgat ccacacgctc
    21601 accttcgcgt cggagcggcg ggacgatggt atcgcgggca cattcgcgac ggcgggcgga
    21661 aggcccgacc cctacgaccc tgccgccccg ctcgaactcg ccgaatcggt gacgttgctg
    21721 gcaaaagtgt cgaagggtac ctatatacgg tccctggcgc gcgatattgc gcgggcgctg
    21781 ggcacttatg gccatgtgac gatgctgcgc cgcacgcgcg cagggccgtt cgccgaggcg
    21841 caggcgattt cgctggacat gctgaacgaa atcggcaagg gcgcgccact tgaacgcatt
    21901 ctcctgccgg tagaggcggg gctggacgac atcccggccc tctccctttc cccggacgcg
    21961 gcaggggcgg tccgacaggg tcgcaaattg tccgggcttg ccgaacccga cggaacctac
    22021 tgggcgaaat cgggcgaaac gccggtcgcc ctcatcgagg tcgcggatgg cgaggcaagg
    22081 gtccttcggg gcttcaacct ttaacaggat gtcgcggagt aagactatgt cggttaccgc
    22141 cgaagaaaaa cagcagatca tccaggacca cgcccgccac gaaggcgaca cgggcagccc
    22201 ggaagtgcag gtcgccatcc tgacccagcg catccgcaac ctgaccggtc acttcgacgc
    22261 gaaccacaag gataaccatt cgcgtcgcgg cctgctggtc atggtcaaca agcgtcgtag
    22321 cctgctcgcc tatctgaaaa agatcgatgt cgagcggtat aacgacctga tcaagaaact
    22381 gggcctgcgc aagtaagccg agagttacgg gaaagcggcc tcatcaaacg ggccgctttt
    22441 tcgcttatgg ggatcgggcc atgccgcgac cccggatcaa tgggcaaggc gaacgcaatc
    22501 cggcgtcgcc gcccgaaaac aggggccgat ttgccccgca ccggaccggg acggttattc
    22561 ccgcacaagc aaaccccgcc cgtgcaatct ggccggcggg attgaggaaa atacatgttc
    22621 gacacgaaaa ccgtatcgat cgagtggggc ggcaagacgc tgacactcga aaccgggcgc
    22681 atcgcccgac aggccgatgg cgccgttctg gcgacctatg gcgaaaccgt ggtgctgtgc
    22741 gccgtcaccg ccgcgcgcaa tgtgaaggag gggcaggatt tcttccccct caccgttcac
    22801 taccaggaaa aattctcgtc cgccgggcgc attcccggcg gcttcttcaa gcgggaacgc
    22861 ggcgcgaccg aaaaggaaac gctgaccagc cgtttgatcg accgtccgat ccgtccgctc
    22921 ttccccgaag ggttctataa cgagatcaac gtcatcgcgc aggtcatgtc ctatgatggc
    22981 gagaccgaac ccgatgtcgt ggcgatgatc gccgcgtccg ccgcgctgac catttcgggc
    23041 gtgcccttca tgggtccgat cggcgcatgc cgcgtcggtt atgaggacgg cgaatacacg
    23101 ctgaacccgt cacaggcgca tgccgccgac accgcgctcg acctgatcgt ggcggcgacc
    23161 ggcaatgccg tgatgatggt cgaatccgaa gccaaggagc tttcggaaga aatcatgctg
    23221 ggcggcgt
//
