LOCUS       NZ_CP060140            26685 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Nodularia sphaerocarpa UHCC 0038 chromosome, complete genome.
ACCESSION   NZ_CP060140
VERSION     NZ_CP060140.1
KEYWORDS    RefSeq.
SOURCE      Nodularia sphaerocarpa UHCC 0038
  ORGANISM  Nodularia sphaerocarpa UHCC 0038
            Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales;
            Aphanizomenonaceae; Nodularia.
REFERENCE   1  (bases 1 to 5451672)
  AUTHORS   Ahmed,M.N., Wahlsten,M., Jokela,J., Nees,M., Stenman,U.H.,
            Alvarenga,D.O., Sivonen,K., Poso,A., Permi,P., Koistinen,H. and
            Fewer,D.P.
  TITLE     Suomilide, a new member of the aeruginosin family
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5451672)
  AUTHORS   Ahmed,M.N., Wahlsten,M., Jokela,J., Nees,M., Stenman,U.H.,
            Alvarenga,D.O., Sivonen,K., Poso,A., Permi,P., Koistinen,H. and
            Fewer,D.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-AUG-2020) Department of Food and Environmental
            Sciences, University of Helsinki, Viikinkaari 9, Helsinki FIN-00014,
            Finland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3; SPAdes v. 3.11.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 77.0x
            Sequencing Technology             :: PacBio RSII; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022376295.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 07:15:30
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,556
            CDSs (total)                      :: 4,496
            Genes (coding)                    :: 4,450
            CDSs (with protein)               :: 4,450
            Genes (RNA)                       :: 60
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 44
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 46
            CDSs (without protein)            :: 46
            Pseudo Genes (ambiguous residues) :: 0 of 46
            Pseudo Genes (frameshifted)       :: 11 of 46
            Pseudo Genes (incomplete)         :: 34 of 46
            Pseudo Genes (internal stop)      :: 13 of 46
            Pseudo Genes (multiple problems)  :: 10 of 46
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:16:42
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1872281
            Orig. end                         :: 1898966
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP060140.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26685
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="PBDE"
                     /region_number="8"
                     /rules="(FMO-like and p450 and DUF98)"
                     /tool="antismash"
     cand_cluster    1..26685
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(FMO-like and p450 and DUF98)"
                     /kind="single"
                     /product="PBDE"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26685
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:16685](+)"
                     /cutoff="10000"
                     /detection_rule="(FMO-like and p450 and DUF98)"
                     /neighbourhood="10000"
                     /product="PBDE"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16685
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(FMO-like and p450 and DUF98)"
                     /neighbourhood="10000"
                     /product="PBDE"
                     /protocluster_number="1"
     misc_feature    488..503
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     gene            complement(640..3720)
                     /locus_tag="BDGGKGIB_RS07515"
                     /old_locus_tag="BDGGKGIB_01529"
     CDS             complement(640..3720)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040095.3"
                     /locus_tag="BDGGKGIB_RS07515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01529"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_239731009.1"
                     /transl_table=11
                     /translation="MPLNQPLTACVVCQRNRGIKLAELLAKKFFTVHLIQHNQGYQFWK
                     EGIKGDIQKQLPESVNAIFIHQSDYNLLNDRNIVSRFIFKFTSDGEPHVQGNELPIYRQ
                     VLLNQLNIEVEDVEEIVAYINQQQVQKPRICLRTNNITEWRNLVETVEFNNLQNRHELL
                     NYLLCNILRNSQERTHEYYDLYRFLGSPQPIVYVLDDYRNYTTYNNDIYKITDSNIREI
                     SKYYRDPETDQNQDFTEVIKGFCLILNNLSIRFDVKAIELNFPASLDNLNVDQLQPTYE
                     LIYHLLNLNNYENQFHVNAAEIAAFIVDIEWLPNITDAQTQQQTNQEWWKKWKQMGVMA
                     IDILSQRYPEIPCYILTGSQPINELQEGLVHRAYWGFEKPKSHHYKTGNDKQPSELLNC
                     ITLEQHLVKAVNRRYGSYQKSPFQQLNIHANSSLWQKLIKKLNIQLPLEQCVRGQALIK
                     LIAGLFPTAQQVEPIKILSGGKSQAQATFLVSPICENNRLATRFIKIGSWFLIQKEYLA
                     YQKVIQPRLNSYTANIIQRPILTEVEQHQMSWGALMYTLAGFPEEYDNLQSLHELFKQH
                     NNSAEGAIDLLKCVKNTLEKVLFPLYKSSFSQEAKTQPVWCWLGDGLPPIYTGVLIPLI
                     KLPGIDCLNENTVSNDIFVIPSAVARNSEGEESWRLAFSNLQELNTKLDEQYQGNKLPE
                     LSLEDLEIVAKDYQKVLLSGWKLMAVEVPGNSNEGELLLVHPILGMRVFLRGDAEDIRL
                     RFGATWLRPGMTVNVLVYLDTKTQRLNNTYKNLSGVDYADNQNNLDLHIREDFKRVNQI
                     DLALRSPVEVFYNDCCHPDNYLSVTGHAAPIHGDLNLNNILYAAGETVGWLIDFERVKT
                     EGLAAYDLAKLEGEIWTNHLLVYINELAKLTPNSIVNNCYKLLYFCLQSLEFLGDEAEF
                     FKTKVRNDQDLAFTSDGLLMPIINLLKVIKLIRDFGVSKCQITLEEMKWSLSAYFLNAA
                     KLNVAPHKRNNAESSMTVFQFLISAWHLAGIVRERGN"
     gene            complement(3711..5381)
                     /locus_tag="BDGGKGIB_RS07520"
                     /old_locus_tag="BDGGKGIB_01530"
     CDS             complement(3711..5381)
                     /GO_function="GO:0004197 - cysteine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012862.4"
                     /locus_tag="BDGGKGIB_RS07520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01530"
                     /product="caspase family protein"
                     /protein_id="WP_239731010.1"
                     /transl_table=11
                     /translation="MKRQALVVGINRYPCHKNSPKSPAAHLKTAASDAKVVARMLELYG
                     NFEVKRLPSKSDISQLDEKEVIRAEELQQAITELFNPQENIPNTALLYFAGHGWREIYE
                     NGETEGFLATSDLNPRRKKYGVSLKWLRQLLQNSCVQQQIVWLDCGYSGELFNFNEREI
                     GTGLTHELWKNEPRRNEGHEEGQEVKRVSESSCVSPIGNQDRCWITATQASERANTIQG
                     RGVLTQALVSSLEPNQDDGGRRVTSDRIIEMIEERVRNNRFNQNPMFYTTGAPIILTGI
                     RGTRWNYQHRLEHLWSETADWFSIGGQDLLIKHTYYHISNYFFGNSRNTGKAQSYKAAI
                     ETALEVTFPDDWWKNQKSIENLHESLKCLCGAVFCGQNEFGDRHITIGSAYLIALMAYA
                     DVFGNTNKLTDEIDLSQFKQLDFPLFPLQEPEQARLSAKALYDLFFCLFEACQNKESEF
                     RQIFFNKEGNKFTIEFTRGADEPKKEGGLSLAEKLPRMLGKDSVPTPKLTNTTSAILRL
                     WRCMLISKDGFMSPGTIYMEKQQLIVSSSFTREITKSCH"
     gene            5524..6012
                     /locus_tag="BDGGKGIB_RS07525"
                     /old_locus_tag="BDGGKGIB_01531"
     CDS             5524..6012
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BDGGKGIB_RS07525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BDGGKGIB_01531"
                     /product="hypothetical protein"
                     /protein_id="WP_239731011.1"
                     /transl_table=11
                     /translation="MVTPPRDRVLLALLLAFRKMTQPLNQSDELILFPQLFEVGEQLQL
                     DPDYWDFIYEGLIAHIINYNVLNQVYQQIYTQIATVDAQILQDISPTTEEVLQVDNVPI
                     YIEMRGDDHNQLNSNNPHFLQIAVTVLKSNNPYIAAQKSDWLNRVTKTLQHLEPSVSL"
     gene            complement(5969..9559)
                     /locus_tag="BDGGKGIB_RS07530"
                     /old_locus_tag="BDGGKGIB_01532"
     CDS             complement(5969..9559)
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024793.4"
                     /locus_tag="BDGGKGIB_RS07530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01532"
                     /product="AAA family ATPase"
                     /protein_id="WP_239731012.1"
                     /transl_table=11
                     /translation="MDKNDFERAFVKLTDGQKQVLEAVLKNPDTRYKEIIANLGITYDT
                     FRKHISSLYKKFNIHKINTYDSPKDKLRKLFKKYKPELLADINDDKETIKDIVIEHSQQ
                     DLADIPVSTNFYGRDVEIKILQTTILENHCQALIITGIYGVGKTSLAVEFAKLIKDKFH
                     FSIARSLENSPSLKTILTDIIQFLSQRQIQELPTDLSGLISLLIEYLKEYRCLIILDNL
                     ETILQSGDRTGKYREEYQGFRQLFRSIITTQHQSCLLLTSREIPQDISLELGENSPVQL
                     LRLKGLELEDSKNIIKNQLLIGAEKEFRQLVQRYEGHPSMLKLIIPIIHDIYSSKISMF
                     LQSKTTELDSINNILDWHFQRLSDIEKQVIYWLAINRDCVTLGELQQDIEQSGVGKNPI
                     NSLKFLLDRSLVNQSALGFKLQPVIREYITERLVTQVCAEIASCKLEIFKSHALIKATA
                     KDYVRESQKNLIVKPIIDALLKVFNTKTQLEAHLKQILSQLPQEQNIGYAGGNLINILI
                     ALEIDLTNYDFSDIKVMQSFLRDVNLHNVNFQNSHFSNAVFKETIAAIFALAFSPDGEI
                     LAIGDYCATIQLLNTKTKEKIFTINYQSGHVVRALAFSPDGQILASGSTNGTIQLWDVT
                     NKTTIEIISAHDDWVHSLAFTPDSQILASGSGDSKIKLWDVQTRKLVKTLSEHRDCVHS
                     VAFNSQGILASGSRDKTIKLWKIDQKRSFKTFEKHTDSVYAVAFSPDGKVLASGSGDST
                     VKLWNIEQLQYLTTLEQHNNIVFSIAFSADGKTLASGAFDSNIQLWDIQDVKNIHHIKT
                     LQEHQNWIRAVAFSPQDHTLASGDIGSIVKLWNLEDINHIDAFTFQGHTSQIRAVAFSP
                     QGNILASASSDKMLRLWNVNRDVNENVNDVQIAETFTGHTDIIYTIAFHPQGTTLASGS
                     ADSTIRLWDVKSRKYIKTLQEPENHLRSLAFSSQSHKFASASRDGSVKLWDIDSGKDEI
                     LLQEDIHPVDCIAFHPHQEFLACGVYNGDVKLWDVSNKQLIKKLPGHTHRINSLAFNPQ
                     GNILASASSDNTIRLWNIDTYECIKILAKHTNWVRSLAFNLHGNILASGSSDGKIILWD
                     MINYEPIKILEAHSAWVYSIAFSPCGKILASGSADETIKLWDVKEVKTATHWRTLTIPK
                     PYEGMNITGSTGLSAEAKATLKALGAVEFL"
     misc_feature    9540..9554
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.75"
                     /tool="antismash"
     gene            10001..11593
                     /locus_tag="BDGGKGIB_RS07535"
                     /old_locus_tag="BDGGKGIB_01533"
     CDS             10001..11593
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) PBDE:
                     FMO-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015121154.1"
                     /locus_tag="BDGGKGIB_RS07535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01533"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_239731013.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-11, bitscore:
                     42.1, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FMO-like (E-value: 9.1e-55, bitscore:
                     184.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDCIIIGAGPGGLACTKELLEQGVREVVCLEKASDVGGVFANTY
                     DNLVLTSSATISMFSDFWIGDGNQHKFWTKQEAVDYWKRYAQHFGVLDYIRFNSKVVNV
                     VRQGREGWQVQLSSGETLLSKRIVLAIGNNAIPKYPDWKDLLTDIDYSHSQEYRNANRF
                     VGKNVVTVGGGESGSDVALETSRVANKSWVSLRNTTGWVAPRKRDIYAADISTHRGVWG
                     LPREYGATLSEAIYQAEWSYKDPVHDAAVELNKKIKASKGVWGIYGTKTFSLPEAIAHH
                     NCKVVGEIVKVEDGGRTLLTADGETLQNVDAVVFSTGYKNYVPFLPEDIRQTDPRTLYK
                     HMFHPTYQDKIAWIGWARPGFGSQFPIMEMQARFFALICKGEQTLPVPAEMERIASLDR
                     AANLGQFEHNAHRIRSLVDYHRYMDDMASLIGCEPPLWQYFFVHFRIWLRMVYGATQST
                     QFRLRGPGQKKSLAHEILMKLPVSKLTHIVKAGLKGRVIYAFKSLIPKSRFTAFKDYRN
                     SSSSIAVSRASSV"
     misc_feature    complement(11907..11916)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.33"
                     /tool="antismash"
     gene            12129..13592
                     /locus_tag="BDGGKGIB_RS07540"
                     /old_locus_tag="BDGGKGIB_01534"
     CDS             12129..13592
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) PBDE:
                     p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="BDGGKGIB_RS07540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01534"
                     /product="cytochrome P450"
                     /protein_id="WP_239731014.1"
                     /sec_met_domain="p450 (E-value: 1.5e-88, bitscore: 295.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLQNLASIQLNDSPPGPPALPFVSMLPFFSKYLHIELHQLGKKY
                     GNIFQLRVGDKKLVVLNNLETVKEALLKQQDSFNARADFDVFQQPPQRYFLELKSGKTW
                     EKHHSIVGQTMHRFLVSKSDTIESLALEQAEDLANMLLQFGSQPVDPDLYVPLATSNFI
                     QRLIFDKKSSLEDTKKDTAFTEYAYSLRYIPCVVEGVKLEFVPGFWQLIFKLSRWKIVP
                     KFLKALAALEHHVAKNVEQHRESFDPDNLRDITDGLLQASSELTDSDRNELGLSENDIV
                     NGTLMQFAGAGGGLPCFTLRWGLLYMITHPDIQTQIQKELDEVVGRTQQPRLEHRSKLP
                     LMGAFINEILRHSSLTTMPPINYATAADTTLEGYFIPKNTPLVINYYALTRDERYWEEP
                     EKFNPYRFLDENGKLRNDLTDKFYPFGMGSRRCIGEYLGRLMIFLFLTNLMHKCKFEKV
                     SGEKLSFASQLGGVFAVPQDFKVVVTPRF"
     gene            13758..15224
                     /locus_tag="BDGGKGIB_RS07545"
                     /old_locus_tag="BDGGKGIB_01535"
     CDS             13758..15224
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) PBDE:
                     p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="BDGGKGIB_RS07545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01535"
                     /product="cytochrome P450"
                     /protein_id="WP_239731015.1"
                     /sec_met_domain="p450 (E-value: 5.6e-88, bitscore: 293.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLQQSASSPLNRISPPGPSALPFVSTLPFLSNYLHIELNKLAKT
                     YGNIYQLRAGRRNFVVLNDLETIKQALVKQKDSFNGRADFEIYRLPPQRYFMEQKSGEP
                     WKRHHSIFGQVMHTLIVDKADMIENWVLEEAADLADVFIKTDGQPFDTDVYMLRATLSF
                     IQRLVFGKRGSINDPQEDPDFVGTAYSVKKLNKGAKCLTKVQISPLLWQPIVFLSCLKP
                     LLGFLLSAPLLERYLGKNIEQHKNSFDPDNLRDVTDGLLKASSELTESDLNELGLSEKD
                     IVKGSLMQFIGAGTALPNVMVRWALLYMIAYPEFQAEIHKELDEVVGREQQPSLEHRSK
                     LPFTAAFLNEVFRHSSATSLPAFVYATTTDTNLEGYFIPNNTPCLVNYYALTRDERYWE
                     DPEQFNPYRFLDENGKLRNDLTDKFYPFGMGSRRCIGEYLGRMMIFLFFTNLMQKCQFE
                     KVSGQKLSLEPQPTMLLIPPDYKIVAKPRF"
     misc_feature    complement(15239..15257)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.99"
                     /tool="antismash"
     gene            15403..15894
                     /locus_tag="BDGGKGIB_RS07550"
                     /old_locus_tag="BDGGKGIB_01536"
     CDS             15403..15894
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="BDGGKGIB_RS07550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="BDGGKGIB_01536"
                     /product="hypothetical protein"
                     /protein_id="WP_239731016.1"
                     /transl_table=11
                     /translation="MANLDSILFVLVTGCLSMASGIFFVLYCLEGPIYSPVLQKNPYDL
                     DSDAQMRRVLLILQQFLTFGLPIVMVTLIISATVGSAFRVALYGFVPLPVLVSLSITFA
                     IIYSGLFVPSAIKIFNSASPEASADKIQAALAPIVRLHRNVGIIVAFTLIMQMASVVFY
                     "
     gene            16092..16685
                     /locus_tag="BDGGKGIB_RS07555"
                     /old_locus_tag="BDGGKGIB_01537"
     CDS             16092..16685
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) PBDE:
                     DUF98"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014054.4"
                     /locus_tag="BDGGKGIB_RS07555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01537"
                     /product="chorismate pyruvate-lyase family protein"
                     /protein_id="WP_239731017.1"
                     /sec_met_domain="DUF98 (E-value: 2.4e-15, bitscore: 54.8,
                     seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSINYIDANLTSRGKIVKGEIQTVFDNEASKLSAFQKILLTANGT
                     VTSMLEAYSSESIQVVKLSEQLDNIALELPNIKLNQQEQVMARKVLLQGKISCRNFIYA
                     DSLILINNLGEKFRNELFNTNKPIGQIWSEQKVETFKEIINHGKESANELAIYFNIKPE
                     ENVFFRTYSVSSQGKITMIITEKFPESYFHQKSN"
     gene            16754..17368
                     /locus_tag="BDGGKGIB_RS07560"
                     /old_locus_tag="BDGGKGIB_01538"
     CDS             16754..17368
                     /NRPS_PKS="Domain: Polyketide_cyc (60-171). E-value:
                     9.9e-19. Score: 59.8. Matches aSDomain:
                     nrpspksdomains_BDGGKGIB_RS07560_Polyketide_cyc.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017313316.1"
                     /locus_tag="BDGGKGIB_RS07560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01538"
                     /product="SRPBCC family protein"
                     /protein_id="WP_239731018.1"
                     /transl_table=11
                     /translation="MSKTNDPNQKTDFSNAIGDLDIEIESETLKSATDSAILQPLEIKI
                     EKLEGRQRKIFAKIQIPYPLEQVWQVLTDYEGLPEFMPNISQSRRLEHPTGGIRLEQLR
                     TKSFMGMNFAVRSVIDVEENFPHEIHYQLIEGDMKALSAYWRLKPWSLSDSKAGIALIY
                     DFLVLPKPIFPMPLVEHILSHDIPASMLAIRQRVEEIYGSK"
     misc_feature    complement(16777..16786)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     aSDomain        16934..17266
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BDGGKGIB_RS07560_Polyketide_cyc.
                     1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="9.90E-19"
                     /label="BDGGKGIB_RS07560_Polyketide_cyc.1"
                     /locus_tag="BDGGKGIB_RS07560"
                     /protein_end="171"
                     /protein_start="60"
                     /score="59.8"
                     /tool="antismash"
                     /translation="IPYPLEQVWQVLTDYEGLPEFMPNISQSRRLEHPTGGIRLEQLRT
                     KSFMGMNFAVRSVIDVEENFPHEIHYQLIEGDMKALSAYWRLKPWSLSDSKAGIALIYD
                     FLVLPKP"
     gene            17614..18435
                     /gene="ntrB"
                     /locus_tag="BDGGKGIB_RS07565"
                     /old_locus_tag="BDGGKGIB_01539"
     CDS             17614..18435
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0015414 - ABC-type nitrate transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015706 - nitrate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ntrB"
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017651185.1"
                     /locus_tag="BDGGKGIB_RS07565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01539"
                     /product="nitrate ABC transporter permease"
                     /protein_id="WP_239731019.1"
                     /transl_table=11
                     /translation="MNLHIRTRNFPKLVRHTFRKQVKQIFPSICGIAGFLTIWHLLSLR
                     PDTILPSPFEVVTSTWDLIRDPFFIKGGNNKGFFWLILASLKRVSIGYVLAALVGIPVG
                     FVISLSSFTKQAIDPIIQLLRPVAPLAWLPMAQAIFLKPDPSAIFVIFITAIWPIILNT
                     ALGVELVPKDYMNVSKVLGLSITENFVKILLPATLPYIFTGLRIAISLSWLAVVAAEML
                     LSDDGLGFFIVNAYNNSDINEIILAVFYLGGVGLILDKMMAYISFKLMPQT"
     gene            18505..19332
                     /locus_tag="BDGGKGIB_RS07570"
                     /old_locus_tag="BDGGKGIB_01540"
     CDS             18505..19332
                     /GO_component="GO:0009898 - cytoplasmic side of plasma
                     membrane [Evidence IEA]"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0015414 - ABC-type nitrate transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0015706 - nitrate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016860188.1"
                     /locus_tag="BDGGKGIB_RS07570"
                     /note="This model describes the ATP binding subunits of
                     ATP-binding cassette (ABC) transporters for nitrate
                     transport, or for bicarbonate transport, in bacteria and
                     archaea; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01540"
                     /product="nitrate ABC transporter ATP-binding protein"
                     /protein_id="WP_239731020.1"
                     /transl_table=11
                     /translation="MYNFVEIRSIGKEFVAPDGGRNIVLKDINLEIKQGEFVSLIGHSG
                     CGKSTLLNIVAGLETSTRGSVEVDGQLVRRPGLDRMVVFQNYSLLPWLTTWENIALAVN
                     KAMPRKSRAERHQIIDAHLEMVGLKDAAAKKPGQLSGGMKQRVALARALAIKPKLLLLD
                     EPFGALDALTRSSLQAELMRICDMSHITTIMVTHDVDEALLLSDRVVMMNNGPSATIGQ
                     ILEIAFEHPRSLTDIVDYPEYQILRHQMLQFLYKQKHERQLETETAFTVHKGV"
     gene            19389..20675
                     /locus_tag="BDGGKGIB_RS07575"
                     /old_locus_tag="BDGGKGIB_01541"
     CDS             19389..20675
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015196743.1"
                     /locus_tag="BDGGKGIB_RS07575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01541"
                     /product="CmpA/NrtA family ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_239731021.1"
                     /transl_table=11
                     /translation="MAKLSRRKFLASAAGAAALTQTLGHYSTSAQRSPGVYIGYRDTPE
                     ITTAKIGFIPVTSCCPLIIAKAKGFFAKYGMPDVEVAKQPSWAVMRDKLMLGSENGGLD
                     GGHLLFPMAYLMATGEITYGRKVPMYILARLNLNGQGVSVSNAYKDLKLGVNSSPLKSI
                     FAQKAKSGKNLLCAIPYRRVTGDFFMRWWLADGGIDPERDVSLIVVPPPQMVANMRAGS
                     MEAFCVVDPWHQRLIKEGIGYSTVTSGELWNNHPEKALAVRADWVDKYPKAAKALLAAV
                     LEAQMWCDRADNKEEMFQIVSQRQWIGMNTDLIRDRILGKFDYGNGRVIENSPHAIKFW
                     RESASYPYKSHDLWFLIEDMRWGYRSPEFETKPLIEAVNREDLWREAAKLIGQEKAIPP
                     STSRGVEKFFNGLKFDPENPQAYLISTNL"
     gene            20760..21452
                     /locus_tag="BDGGKGIB_RS07580"
                     /old_locus_tag="BDGGKGIB_01542"
     CDS             20760..21452
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006195168.1"
                     /locus_tag="BDGGKGIB_RS07580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01542"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_239731022.1"
                     /transl_table=11
                     /translation="MFEKQPEGLQQRVKELANQAIEEANPTAWFDVLYSQSQGDVTQIP
                     WAKLTCHPYLQDWLTIHDTQGEGLSALVIGCGLGDDAQALADRGFQVTAFDISPTAIDW
                     CQQRFPDSAVNYVVADLLNLPAQWHQAFDLVVEIRNIQALPLSLRSTVIASVASVVAAT
                     GTLLVINRFRDTDIEPDGPPWPLSDSELAQFTELGLQEVSRVQFYEGERVDVPQLRLEY
                     QKSVPPKV"
     gene            complement(21515..22195)
                     /gene="lipB"
                     /locus_tag="BDGGKGIB_RS07585"
                     /old_locus_tag="BDGGKGIB_01543"
     CDS             complement(21515..22195)
                     /EC_number="2.3.1.181"
                     /GO_function="GO:0016979 - lipoate-protein ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009107 - lipoate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="lipB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009458472.1"
                     /locus_tag="BDGGKGIB_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01543"
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="WP_239731023.1"
                     /transl_table=11
                     /translation="MIRSMEADYRRCLLFNAGLMPYTEALFWQRSLLQERILQPSLDDV
                     LILLEHPPVYTLGQGSNPEFLKDLDQSKFDVHRVERGGEVTYHCPGQVVGYPILNLQYY
                     CKDLHWYLRQLEEVLIRVLAVYGLTGDRLPGFTGVWLEGRKVAAIGIKVSRWITMHGFA
                     FNVCPDMSGFKQIIPCGIADKPVASLAEWIPGITCEEVRVNIADCFAEVFGVELVETMK
                     KWDF"
     gene            22589..23230
                     /gene="raiA"
                     /locus_tag="BDGGKGIB_RS07590"
                     /old_locus_tag="BDGGKGIB_01544"
     CDS             22589..23230
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_component="GO:0022626 - cytosolic ribosome [Evidence
                     IEA]"
                     /GO_function="GO:0045182 - translation regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0009386 - translational attenuation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="raiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006195165.1"
                     /locus_tag="BDGGKGIB_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01544"
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="WP_239731024.1"
                     /transl_table=11
                     /translation="MKLVIHGKNIEITDAIREYVHLKIEKAVSHFQNITNEVDVHLSVA
                     RNPRITTKQAAEVTIFANGSVIRAEESSENLYASIDLVADKIARQLRKYKERLQDQKTN
                     APPTNQVLVPEPVAADLIGDRTPELPNEVVRTKYFSMPPMTVAEATQQLQLVGHDFYMF
                     HNSETGEMNVIYERNHGGYGVIQPRHSNGHTNGKNGNSAQAVPAKAHSHK"
     gene            complement(23404..23862)
                     /locus_tag="BDGGKGIB_RS07595"
                     /old_locus_tag="BDGGKGIB_01545"
     CDS             complement(23404..23862)
                     /EC_number="1.11.1.24"
                     /GO_function="GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006195164.1"
                     /locus_tag="BDGGKGIB_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01545"
                     /product="peroxiredoxin"
                     /protein_id="WP_239731025.1"
                     /transl_table=11
                     /translation="MSVKVGDTAPDFSLCAQNGSTVSLSAFRGQKAVVLYFYPKDDTPG
                     CKAESCAFRDQYEVFKTAGAEVIGVSGDSNESHQKFAQKYNLPFQLLSDKGDQVRKQYG
                     ATAMFGFVPGRVTYVIDKEGVVKYVFDSMLNFKGHVEEALKTLQQLAV"
     gene            complement(23883..25814)
                     /locus_tag="BDGGKGIB_RS07600"
                     /old_locus_tag="BDGGKGIB_01546"
     CDS             complement(23883..25814)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016874605.1"
                     /locus_tag="BDGGKGIB_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01546"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_239731026.1"
                     /transl_table=11
                     /translation="MSIITLQSVKKDFGIKELLRDASFSLDATDKVGLIGTNGSGKSTL
                     LKMIAGLESIDSGQITFSSGAKVIYLPQQPDLDENHTVLEQIFADSGEHLALVREYEEL
                     SHKLVHHPEDSQLMSRLSGVMQRMETAGAWELETNAKIILTKLGISDFDAVIGTLSGGY
                     RKRIALATALLSEPDVLLMDEPTNHLDALSVEWLQSYLNRFRGALLLITHDRYFLDQVT
                     NRIIEIDRGDIYTYSGNYSYYLEKKALAEESAISSQRKHKGILRRELEWLSRGPKARST
                     KQKARIQRVESLRETEFKQVQGKVDISTVSRRIGKKVIELNNISKGYDGRTLIKDFTYE
                     FSPEDRIGIIGGNGTGKSTLMDMITKRIQPDSGNVDIGTTIHIGYFDQHSEELLSAVDE
                     NQRVIDYIKEEGEFVKVSDGTQISASQMLERFLFPGNQQYAPINKLSGGEKRRLFLLRI
                     LIGAPNVLILDEPTNDLDVQTLAVLEDYLEDFPGCVIAVSHDRYFLDRTVDTIFALEEG
                     GNLRKYPGNYSIYLDYKKAEEEEAKQQQAANTKEKPKEDVKVAASSSDSDNKKRRRLSN
                     WEKREFEELEGKIAKLETEKATVEKALVNVSAGNYTQVQKLYEQVETLKHSIDTATERW
                     LELAEIDA"
     misc_feature    complement(26082..26094)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.11"
                     /tool="antismash"
     gene            complement(26202..26624)
                     /locus_tag="BDGGKGIB_RS07605"
                     /old_locus_tag="BDGGKGIB_01547"
     CDS             complement(26202..26624)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011319761.1"
                     /locus_tag="BDGGKGIB_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="BDGGKGIB_01547"
                     /product="DUF1824 family protein"
                     /protein_id="WP_239731027.1"
                     /transl_table=11
                     /translation="MTTPNHQNLTISEATKILHKFNCLDIAPILKPSEKALVRRALTLV
                     ASISDYQILGICADTAEDGILAMRTYSHAFGYEVPSDLATPEGPVYIKLNGKNGLCYLD
                     SYSGHHRGVLISCQSYNEGGINEMYGHLPLDLFAEN"
ORIGIN
        1 tgaagtcaga ctgggattta gtcctttcag aagcatttct gtgaaagcgc catgtttacc
       61 actaggacta ctgtaagcac cttcaaactc tcttgatgcg gttacaaaaa agcgcatttt
      121 gtcatatgct accatctgca aatcatcaaa ggaaaaatta aataattcgc cactgtgaca
      181 acagtctaaa aaaataattt gttgtttaat tggactatta tttaagattt gacgtaaccg
      241 atgcaacgat acaccacaaa tattttttct gggactcgca tcactgctgg ctaagtaacc
      301 ttgtctgatt ccaccttcag gctggttttg tagtccatgt ccagcgaaaa acaacaaagc
      361 agtatcaggt attctgtctc cttctggctg aaagagtttc tttatggcgg tttccaattc
      421 tgctactgtc accagttgtt gaggatcaac ttggaaccta tcatcaatga acctttgggg
      481 aagacgagtc accctaaagt taccatgagt ttctagaact tgggcgatcg cttccgcatc
      541 ttcagcagcc agttttaaat gtttactttc acttgtgggt gtttccttaa acaaaggata
      601 acgattgata ccgataacta aagcatctcg attcattact taattacctc tttcacgaac
      661 aattccagct aaatgccatg ctgatattaa aaattggaac acagtcatag aactttcagc
      721 attatttctc ttgtgcggtg caacatttaa cttagctgca ttcaagaaat atgctgacaa
      781 tgaccatttc atctcttcta atgtaatttg gcattttgat acaccaaaat cacggataag
      841 cttaatcacc ttcagcagat taattatcgg cattaataaa ccatcagagg taaaagctaa
      901 atcctgatca tttctcacct tcgtcttaaa aaattctgct tcatctccca aaaactctaa
      961 cgattgcaaa caaaaataga gtaacttata gcaattatta actatactat taggtgtcag
     1021 ctttgccaac tcgtttatat aaactaatag atgatttgtc caaatctccc cctctaactt
     1081 cgctaaatca taagcagcca aaccttctgt tttcactcgt tcaaaatcaa ttaaccaacc
     1141 taccgtttca ccagcagcat aaagaatatt atttaaattt aaatccccat gaatcggtgc
     1201 tgcatgacca gttacagata aataattatc tgggtgacaa caatcattat aaaaaacctc
     1261 cacaggtgaa cgtaaagcta aatctatctg attcaccctt ttaaaatctt cccggatatg
     1321 taaatctaaa ttattctgat tatctgcgta atcaacgcct gataaatttt tataagtatt
     1381 atttaatctt tgagtttttg tatccaaata aactaaaaca ttgacagtca tccctggacg
     1441 aagccatgta gcaccaaacc gtaaacgaat atcttccgca tcacctcgta aaaacactct
     1501 cattcctaaa attggatgca ctaacaagag ttctccctca ttgctattac ctggaacctc
     1561 aacagccatt aacttccaac cagatagcaa aactttttga tagtctttag caacaatttc
     1621 cagatcctca agtgatagtt ctggaagttt atttccttga tattgttcat caagtttagt
     1681 attcagttct tgcaaattag aaaatgctaa tctccaactt tcttcacctt cgctattcct
     1741 cgcaacagcc gatggaatta caaatatatc attagaaact gtattttcat ttaaacaatc
     1801 aattccaggt aattttatta atggtatcaa aactcctgta taaataggag gaagcccatc
     1861 acccagccaa caccacacag gttgtgtttt agcttcctga gaaaagctag acttataaag
     1921 tggaaataac accttttcta aagtattttt cacacatttt aataaatcaa tagccccctc
     1981 agcactgttg ttatgctgtt taaataattc atgcagagat tgtaagttat catattcttc
     2041 tggaaatcct gccaaggtgt acatcaaagc accccaagac atttggtgtt gctcgacttc
     2101 tgttaaaatt ggtctttgaa tgatgttagc agtataactg ttgagtcggg gttgaattac
     2161 cttttgatac gctaaatatt ctttttgaat caaaaaccaa gaaccaattt taataaaccg
     2221 agttgctaaa cggttatttt cacatatagg actaactaaa aaagttgctt gagcttgaga
     2281 ttttccgcca gagagaattt taatcggttc tacttgctgt gcagtgggga aaagacctgc
     2341 aattaatttt atcagagctt gaccgcgcac acattgttct agagggagtt gaatgtttaa
     2401 ttttttaatt aatttttgcc ataaactaga attagcatgg atatttaact gttgaaatgg
     2461 tgatttttgg taagaaccat aacgacgatt aactgcttta actaaatgtt gttctaaagt
     2521 gatgcagttg agtaattcac tgggttgttt atcattacca gtcttataat gatgagattt
     2581 aggtttttca aatccccaat aggcgcgatg tactaatcct tcttgaagct cattgatagg
     2641 ttgagaacct gtcaaaatat agcaaggaat ttctggatag cgctgggaaa gaatatcaat
     2701 agccattacc cccatttgct tccatttttt ccaccattcc tgatttgttt gttgttgagt
     2761 ttgtgcatct gttatatttg gtaaccattc tatatcgaca ataaaagcag caatttccgc
     2821 agcattaaca tggaattggt tttcataatt attcaagttt aaaaggtgat agattaattc
     2881 ataggtaggt tggagttgat caacatttaa attatctagt gatgctggga aatttaactc
     2941 aatagctttg acatcaaatc tgatagataa attatttaaa attaaacaaa aacctttgat
     3001 tacttctgta aaatcctgat tttgatctgt ttctggatca cgataatatt tagaaatttc
     3061 tctgatgttt gagtctgtaa ttttgtatat atcattatta taagtagtat aattcctgta
     3121 atcatctaaa acataaacga tgggttgtgg actacctaaa aacctatata aatcataata
     3181 ctcatgtgtt ctttcttgag aattacgcaa aatattacac agcaaataat ttaaaagttc
     3241 atggcgattt tgtaggttgt taaattctac agtttctact agattccgcc attctgtaat
     3301 gttattagtg cgaaggcaaa tccgaggctt ttgtacctgt tgttgattga tataagctac
     3361 aatttcctca acatcttcta cttcaatatt taactgattt agtaaaactt gcctataaat
     3421 aggtaattca tttccttgta catgaggttc accatcagaa gtaaatttaa atataaatct
     3481 cgaaacaata tttctatcat tcaaaaggtt gtagtcactt tgatgaataa aaatagcatt
     3541 tactgattcg ggtaattgtt tttgtatgtc tccttttatt ccttctttcc aaaattgata
     3601 accctggtta tgttgaatta aatgaacagt gaaaaatttc tttgctaaaa gttctgctaa
     3661 ttttatacct ctgttacgct gacagacaac gcacgctgtt aaaggttgat ttaatggcat
     3721 gattttgtta tttcccttgt gaaggagcta cttactatga gttgttgttt ttccatataa
     3781 atagtacctg gactcataaa gccatcttta ctaatcaaca tacatctcca taaacgaaga
     3841 atagctgatg ttgtattggt taattttggt gtgggtacac tatctttacc tagcattcgg
     3901 ggtaattttt ctgctaaact taaccctcct tcctttttag gttcatctgc gcccctggta
     3961 aactcaattg taaatttatt cccttctttg ttaaaaaata tttgtctaaa ttcagattcc
     4021 ttattttgac aagcttcaaa taagcagaag aagaggtcat ataaagcttt agctgataat
     4081 ctagcttgct caggctcttg aagaggaaat aatgggaaat caagttgttt aaattgggat
     4141 aaatctatct catcagtcag cttatttgta tttccgaaaa catctgcata agccattaat
     4201 gctattaagt aagctgaacc aattgtgatg tggcgatcgc caaattcatt ctgtccgcaa
     4261 aatacagcgc cgcaaagaca tttcagagat tcatgcaagt tttcaattga cttctgattt
     4321 ttccaccagt catcaggaaa agttacttct aaggctgttt ctatagccgc tttataactc
     4381 tgagctttac ctgtatttcg agaattacca aaaaaataat tactaatatg atagtaagta
     4441 tgtttgatta ataaatcttg accacctatg gaaaaccaat cagcagtttc actccaaaga
     4501 tgctcaagac gatgttgata attccatctg gttcctctga ttccagtcag gataatagga
     4561 gcgccagttg tgtaaaacat agggttctga ttgaacctgt tatttctaac tcgctcttca
     4621 atcatttcga tgatgcgatc gctcgttact cttctaccac catcatcctg atttggctca
     4681 agactagaaa cgagagcctg agttaataca ccacgtccct gaattgtgtt agcgcgttca
     4741 gatgcttgtg tagctgtaat ccaacaacga tcttgattac ctataggact tacgcaagaa
     4801 ctctctgaaa ccctcttgac ttcctgtcct tcttcgtgtc cttcgttcct tcgtggttca
     4861 ttcttccata actcgtgcgt aagtcctgta cctatttccc tttcattaaa gttaaataac
     4921 tccccactat aaccgcaatc gagccatact atttgctgtt gtacacaact gttctgcaat
     4981 aactgacgca accattttaa agaaacgcca tattttttac gtcgaggatt tagatcactg
     5041 gtggctagaa aaccttctgt ctctccattt tcataaattt ctcgccaacc atgaccagca
     5101 aaatacaaca gtgctgtatt gggaatattt tcctgtgggt taaataactc tgtaatcgct
     5161 tgttgcagtt cttctgcccg aatcacttct ttttcatcta gttgtgatat gtctgactta
     5221 ctaggtaatc gcttgacctc aaagttacca tacagttcta acattcgcgc cacaactttc
     5281 gcatcactag ctgctgtttt caaatgtgca gctggacttt taggcgaatt tttgtggcaa
     5341 gggtaacgat tgataccaac aactagcgct tgacgtttca taaaatatac aaattaatcc
     5401 ttggggaaat tgctttgtac ccctgataag tttaataaca tcatacccac gccaatagga
     5461 ttgtataatt tatgcaggaa tatctttaca aataacgaat ttcaacacta aggtgcatat
     5521 ttcatggtta caccaccccg tgacagagtt ttgctggctt tattgctagc tttcaggaaa
     5581 atgacacaac cactcaacca gtctgatgaa ctgatattat ttcctcagtt attcgaggta
     5641 ggtgaacagc tacagctaga tccggattac tgggatttca tctatgaggg attaattgct
     5701 cacattatca attacaatgt cttaaatcag gtttatcaac agatatatac tcaaatcgca
     5761 actgtagatg ctcagatact ccaggatatc tcacccacca cagaggaagt gttacaagtg
     5821 gacaacgttc ctatttatat tgagatgcgg ggagacgatc ataatcaact aaactcaaat
     5881 aatccccact ttctgcaaat agctgtcaca gtgttaaaaa gtaataaccc ttacatagca
     5941 gcgcaaaaat ctgactggct gaatcgggtt acaaaaactc tacagcacct agagccttca
     6001 gtgtcgcttt agcttctgca cttaaacctg tacttcctgt aatattcatt ccctcgtagg
     6061 gtttaggtat tgttaaagtc cgccaatgag tagcagtttt aacttctttc acatcccata
     6121 acttaatagt ttcatcggcg ctaccactag caagtatttt cccacaagga ctaaaggcga
     6181 tggaatatac ccaagcgcta tgtgcctcta aaatcttgat gggttcatag ttaatcatat
     6241 cccaaagtat gattttacca tcactactac cactagctaa gatattgccg tgaagattga
     6301 aagctagtga acgtacccag ttagtgtgtt tagccaaaat tttgatacat tcataagtat
     6361 caatattcca caacctgatg gtgttgtcac tactagcact agctaaaatg ttgccttgag
     6421 ggttgaaagc aagtgaattt atcctgtgag tatgacctgg taactttttt ataagctgct
     6481 tattgctaac atcccataac ttgacatcgc cattataaac gccacaggct aaaaattctt
     6541 gatggggatg aaaggcaata caatctacgg ggtgaatatc ttcttgcaat agaatctcat
     6601 cttttccaga atcaatatcc cacagtttca cactcccgtc acgacttgca ctagcaaact
     6661 tgtgactttg agaactaaaa gctagagagc gcagatgatt ttcaggttcc tgtagagttt
     6721 tgatgtattt acgagatttt acatcccata acctgatggt tgagtcagca ctaccactgg
     6781 ctaaagttgt tccttggggg tggaaagcaa ttgtatatat tatgtctgta tgtccggtaa
     6841 aggtttctgc aatttgaacg tcattcacat tttcattcac atctcgattc acattccata
     6901 gtcgcagcat tttatcactg ctagcactag caaggatgtt accttgggga ctgaaagcta
     6961 ctgcacgaat ttgactggtg tgtccttgaa aagtgaaagc atcaatgtgg ttgatatctt
     7021 ccaggttcca caacttgact attgagccaa tatccccact agcaagggtg tgatcttggg
     7081 gactaaaagc cactgcacga atccaatttt gatgttcctg taaggttttg atatggtgaa
     7141 tatttttcac gtcttgaata tcccatagtt ggatattgct gtcaaatgca ccactggcta
     7201 aagtttttcc atctgcacta aaagcaattg aaaacacaat attattgtgt tgctctaagg
     7261 tggtgagata ttgtagttgt tcaatattcc atagcttgac agtggagtca ccactaccac
     7321 tagctaaaac tttaccatcg gggctaaagg caactgcata cactgagtct gtgtgttttt
     7381 caaaagtttt gaaactccgc ttttgatcta tcttccacag tttgatagtt ttgtctctac
     7441 taccactagc taggatacct tgagaattaa aggctactga atgtacacaa tcacgatgtt
     7501 ctgataaagt tttgacaagt ttacgagtct gaacatccca gagtttgatt ttagagtcac
     7561 cactaccact ggctaatatt tgactatcgg gagtgaaagc tagggaatgt acccagtcat
     7621 catgggctga tataatctct atggttgttt tatttgtgac atcccataat tgtatggttc
     7681 cattagtgct accactggct aatatttgac catcgggact aaaggctaag gctcggacta
     7741 catgaccaga ttgatagtta attgtgaaaa tcttttcttt tgttttagtg ttcaatagtt
     7801 gaattgtggc gcaataatca ccgatagcca agatttcacc atcgggacta aatgctaaag
     7861 caaaaatagc ggcgattgtt tctttaaaaa ccgcattgga gaaatgacta ttttggaaat
     7921 tgacattatg caaattcaca tctctcagga acgattgcat aactttgatg tcagaaaaat
     7981 cgtaattagt taagtcaatt tctaaagcaa tgaggatatt gattaggttc ccgccagcat
     8041 atcctatgtt ttgttcttgt ggcagttgtg atagtatttg ttttaaatga gcttccagtt
     8101 gagttttagt attaaaaact ttcaggagcg catcgataat cggtttaact atcaagtttt
     8161 tttggctttc ccgcacatag tctttggctg tagcttttat taaagcatgg cttttgaaaa
     8221 tttctaattt acaactggca atttctgcac agacctgtgt tactaaacgt tctgtgatat
     8281 attccctaat cacaggttgt agtttaaagc ctaatgcact ttgattgaca agtgaacgat
     8341 ctagtaagaa tttcagagaa ttgatgggat ttttgccgac tcctgattgt tctatgtcct
     8401 gttgtaattc tccgagggtt acgcagtcac gattaattgc taaccaatat atgacttgct
     8461 tttctatatc tgatagtcgt tgaaagtgcc aatctaaaat attgttaata ctatctaact
     8521 cagttgtttt agattgcaaa aacatggata ttttgctact ataaatatca tggattatgg
     8581 gaataatcag cttgagcatg gaagggtgtc cttcgtagcg ttgcactaat tgtctaaatt
     8641 ctttttctgc accaattagc agttgatttt tgatgatatt tttactgtct tctaattcta
     8701 agcctttgag cctcaataat tgtactggtg aattttcccc tagttctaga gaaatgtctt
     8761 ggggaatttc tcgactggtg agcaataaac aactttgatg ttgggttgtg atgatactac
     8821 ggaaaagttg gcgaaatcct tgatattctt ctctatattt tcctgtgcga tcgcctgatt
     8881 gtaagatagt ctctaagtta tccaaaataa ttaaacagcg atattctttt aaatattcaa
     8941 ttagcaggga tatcaagcca cttaaatctg ttggtaattc ttgtatctgg cgttgagata
     9001 agaactgaat tatatctgtg aggatggttt ttagagaggg tgaattttcg agtgatcgcg
     9061 ctatagaaaa atggaattta tccttaataa gtttggcgaa ctccaccgcc aaagaagttt
     9121 tcccaactcc ataaatacct gtgattatta atgcttggca atgattctct aaaatcgttg
     9181 tttgcagaat tttaatttct acatctcgcc catagaaatt tgtggatact ggaatatctg
     9241 ccaaatcttg ctgagaatgc tcaattacta tgtcttttat agtttctttg tcgtcattga
     9301 tatcggctaa taattcaggt ttatactttt taaataattt tcttagctta tccttcgggg
     9361 aatcataggt attgattttg tgaatgttaa atttcttata caaagatgat atgtgttttc
     9421 taaaagtatc ataagtaatt cctaaattag caataatttc tttatatctt gtgtcgggat
     9481 ttttcaaaac agcttctaaa acttgttttt gcccatctgt tagtttcaca aaagcccgct
     9541 caaaatcatt tttatccata tttaaaaatc ctttattcac aaaatctaca aaatattcac
     9601 aaaaatcatt cacaaaaata tttttattca catcgatata ttttttataa tcagtatgct
     9661 ataaaaatta cattcaatgt tgaggaaaat ttatacacga tagagaatca tcaataacct
     9721 tctctagctt tttggtgtgt catgtaaatt ttacgtgagc attaccggga acatcaaacg
     9781 agcaaatgag cattaaaaca aatcatacaa agatggtgaa aataatacaa cacatcctct
     9841 aaactgcatt ggattgtcat gcatagtcat aagtaaggat tttagcgatc gctcttttcg
     9901 acaaaattat caaagctctt attttggcta aagcattgag aagttgaagg acagagttat
     9961 cggtttagta agtaacttag caatagaaag gtgaactacc atgttagatt gtattattat
    10021 tggagccgga cccggaggtt tggcttgtac gaaagaatta ctcgaacaag gtgtccgcga
    10081 ggttgtgtgt ttagaaaaag cctctgatgt agggggcgtt tttgccaata cttacgataa
    10141 tttagtattg acttcctctg ccactataag tatgttttcg gatttttgga ttggcgatgg
    10201 aaaccagcac aaattctgga ctaagcagga agcagttgat tattggaaga gatacgccca
    10261 acattttggt gtcctcgatt acatccgttt caactccaaa gtagtgaacg tggttcgaca
    10321 aggtagggaa ggctggcagg ttcagctatc atctggagaa actttgctct caaaacggat
    10381 cgtattggca atcgggaaca atgctatccc taaatatcca gattggaagg acttattaac
    10441 tgacattgat tactcccatt cacaggagta tcgtaatgct aacaggtttg taggtaaaaa
    10501 cgttgtgaca gttgggggag gtgaatctgg ctcggacgta gcattagaaa catcccgcgt
    10561 agcgaacaag tcctgggtaa gtctgcgtaa cacaacagga tgggtggcac cccggaagag
    10621 agacatatac gctgctgata tttctaccca tcggggcgtg tggggtcttc ctcgtgaata
    10681 tggagcaact ttaagcgaag ctatctatca agccgagtgg agctacaaag acccagttca
    10741 tgatgcagca gtggaactca acaagaagat taaagccagc aagggagtct ggggaattta
    10801 cggaaccaaa accttttcat tacccgaggc gatcgcccat cacaattgta aagttgttgg
    10861 tgaaatagtg aaagtagaag atggcggaag aacattactc accgcagacg gagaaaccct
    10921 gcaaaatgtc gatgccgttg tattttctac tgggtacaaa aattatgtgc cttttctacc
    10981 ggaagatatt aggcaaactg acccccgcac cctctataaa catatgtttc atcccacata
    11041 tcaagacaag atagcttgga ttgggtgggc ccgccctggc ttcggcagcc aatttcccat
    11101 tatggagatg caggcgagat tttttgccct gatttgcaaa ggagaacaaa ccctccctgt
    11161 tcctgctgaa atggaacgga ttgcatccct ggatcgcgca gctaatttag gtcagttcga
    11221 gcataatgct catcgaatcc gaagcttggt tgattatcat cgttacatgg atgatatggc
    11281 tagtttgatt ggatgtgagc ctcctctgtg gcaatacttt tttgtccact tccgcatttg
    11341 gcttcggatg gtatatggtg ccacccagtc tactcagttt cgcttgcgag gtcctgggca
    11401 gaagaagtcc ttagctcacg agatattgat gaaactacct gtgagtaaac taactcacat
    11461 cgtcaaagca ggtctgaaag gacgtgtgat ttatgctttc aaatctttaa tccctaaatc
    11521 cagatttacg gcttttaaag attaccgaaa ttcctcatct tctatcgcag tttctagagc
    11581 ctcctctgtt tgatctgacc cacattatat ctagcaaatc ctcataaatc tcttgcataa
    11641 attcaacctg aaaaaggtat ctcaagagaa cttgagtttt taagcacaac tagaattatt
    11701 cgtaattcca gaagataaac agctttgtct ttagaccttg cttttaggat tgaggatttg
    11761 attgaaattg tcagtaatta tgaacttact tgtggcattt ataaagtgta gaactagaac
    11821 ttacgcaata actctcactt cggcaacctc cattcggcaa gctcagggca tcgcagtgac
    11881 cactgcaacc ctctttcctt agtgtccttc gcgttcttct cccttggcgc tagcctctcc
    11941 ctttgggaga aggggagacg ctacgcgaac gtggttcgtt ttttcataat tttgcgtaag
    12001 tcctgaagtg ttcaatctta gccaagataa cagtaattta tcaggggggt gaaaacttta
    12061 tctcaacccc tcagatagac actatttctg ttattaatgc ttgtcctcaa tgtatctcaa
    12121 aaatagctat ggttttgcaa aatttagcct ccatacagtt gaatgatagc cctccaggac
    12181 ctcctgcact gccctttgtc agtatgttgc ccttcttcag taaatacttg catatagaat
    12241 tgcatcaact cggcaaaaaa tacggtaata tctttcagct tcgcgtagga gataaaaagt
    12301 tagttgtact aaataacctt gagactgtca aagaagcttt attaaagcag caagatagct
    12361 ttaatgctag ggctgatttt gatgtctttc agcaaccacc tcaacgttac ttcctcgaac
    12421 tgaaaagtgg taagacatgg gaaaaacacc atagtattgt aggtcaaact atgcataggt
    12481 ttttggtgag caaatcagat actattgaaa gcttggctct tgaacaagca gaagacttag
    12541 caaatatgct cttacaattt ggcagccaac ctgttgaccc agatttatat gtacctttag
    12601 ccacctccaa ctttatccaa agacttatct ttgataaaaa aagtagtctt gaagatacaa
    12661 aaaaagatac cgcatttaca gaatatgctt atagtttaag gtatattccc tgtgttgtag
    12721 agggtgttaa attagagttt gtaccaggat tttggcaact gatattcaaa ttatcacggt
    12781 ggaaaatagt accgaagttt ctcaaggctt tagctgcatt agaacaccat gttgcaaaaa
    12841 acgtagaaca gcatcgagag tcttttgatc cagacaattt gcgggatatt acagatggac
    12901 ttctacaagc tagtagcgaa ctaactgatt cagatagaaa cgagctggga ttaagtgaaa
    12961 atgacattgt taatggaaca ttgatgcagt ttgccggagc tggtggcgga cttccctgtt
    13021 ttacattgcg ctggggtttg ctatacatga tcactcaccc agatattcag actcaaatcc
    13081 aaaaagaact ggatgaagtc gttggtagaa cacaacaacc acgcttagaa catcgtagta
    13141 aattaccact catgggagct tttattaacg aaatcttgcg tcattcttct ctgactacta
    13201 tgccccccat caattacgcc actgctgctg ataccacttt ggaaggttac tttattccca
    13261 aaaatactcc tttagttatc aattactatg ctctcacccg tgatgagcgt tattgggaag
    13321 agcctgaaaa atttaacccc tatcggtttt tagatgaaaa cggcaagctg agaaacgatc
    13381 ttactgataa gttttatcca tttggcatgg gatcgcgtcg ctgcatagga gagtatttag
    13441 gacgtttgat gatatttcta ttcttgacta acctcatgca taaatgcaag tttgaaaaag
    13501 tttctggaga gaaattaagt tttgcatctc aactaggagg agttttcgcc gttccacagg
    13561 actttaaagt tgtagtaaca ccacgctttt agattctaaa atttgaattt tgagtagtgt
    13621 aatcgttttt ttgaaatata gaactgctgc atttgatcag aggtaattta tcagggattg
    13681 agactaagtt ttcacttcct cagacgaaaa accttttggt ttgtaatatt tgtcctcaat
    13741 ttatctggag aataactatg gttttgcaac aatcagcctc ttcaccatta aacagaattt
    13801 cccctccggg accgtctgca cttccatttg tcagtacctt gccattcctc agtaattact
    13861 tacatataga attgaataaa ctagccaaaa cctatggcaa tatttatcag cttcgcgcgg
    13921 ggcggagaaa ctttgttgta cttaatgatc ttgaaactat caaacaagcg ttagttaagc
    13981 agaaggatag ctttaacggt agagccgatt ttgagattta tcggctacca cctcaacggt
    14041 acttcatgga gcagaagagt ggcgaaccct ggaaaagaca ccacagcatt ttcggccaag
    14101 tcatgcatac cttgatagta gacaaggcag atatgattga aaattgggtt ctagaagaag
    14161 ccgcagactt agcagatgtc tttataaaga cagatggtca accttttgac actgatgtat
    14221 atatgcttag agccacctta agttttatcc aaaggctcgt ctttggtaaa agaggtagta
    14281 ttaatgatcc tcaagaagat cctgattttg tgggaactgc ttatagtgtc aaaaagctta
    14341 acaaaggcgc taaatgtctg acaaaggtgc aaatttcacc gcttctttgg cagccaatag
    14401 tatttctttc ttgcttaaag ccattactag gttttctttt atcagcgccc ctattggaac
    14461 gctatcttgg caaaaatata gaacagcata aaaattcctt cgatccagac aatctgcggg
    14521 atgttacaga tggacttttg aaagctagta gtgaactcac tgagtcagat ctaaacgaac
    14581 ttggcttaag cgaaaaagat attgttaagg gatcattgat gcaattcatt ggggcaggta
    14641 cggcacttcc caatgttatg gtacgctggg ctttgcttta catgattgcc tacccagagt
    14701 tccaggctga aattcataaa gaactggatg aagtagttgg cagggagcaa caaccaagtt
    14761 tagaacaccg tagcaaatta ccatttacag ctgcttttct gaatgaggtc ttccgccaca
    14821 gttctgctac tagtttacct gcctttgttt atgctactac cactgatacc aatttagagg
    14881 gttactttat tcctaacaat actccttgtc ttgtaaatta ctatgctttg acccgtgatg
    14941 agcgctattg ggaagacccc gaacaattta atccataccg attcttggat gaaaacggca
    15001 aacttagaaa cgatctaact gataagttct atccatttgg aatgggatcg cgtcgctgca
    15061 taggagagta tttaggacgt atgatgatat ttctattttt cactaacctc atgcaaaaat
    15121 gccagtttga aaaagtttct ggacaaaaat tgagtcttga gcctcagcca acaatgttac
    15181 tcattccacc ggactataaa attgtagcaa aacctcgctt ttaggcttta gagtctcaat
    15241 tgcgagtcgg tagcgatatc cgccttgtac catttctgta taaagttgcg ccgaatttct
    15301 ttgtgtactt tgcgtgcttc tcccaaaggg agaggctacc gccaatgcgg ttatctctac
    15361 attctgtaca tattcacatc ttttactatc agggcttaaa aaatggcaaa cttagattca
    15421 atactcttcg tacttgtaac aggttgcctg agtatggcga gcgggatttt ttttgttctt
    15481 tactgtctcg aaggacctat atatagtcct gttttgcaga aaaatcccta tgatcttgat
    15541 tcagacgcac aaatgcgccg cgtgttacta atactgcaac agttcctcac atttggttta
    15601 cctattgtca tggtaactct aatcatctct gctacggttg gctctgcatt tcgcgtggca
    15661 ctctacggtt ttgttccctt gccagtattg gttagtctca gcatcacgtt tgctattatc
    15721 tacagtggat tgtttgtacc gtcagcaatc aagatattta acagtgcaag tcctgaagcc
    15781 tcagccgata agatccaagc agcacttgct cccattgtgc gtctccatcg caacgttggg
    15841 attatcgttg catttaccct aattatgcag atggcaagcg tggttttcta ctaggcattt
    15901 cggtcaataa taacctgaac agtatttata tgtaacacgg agaaacacag gttatttacg
    15961 ttgagtagcg ctgacttact tactattagc agcctggtga taaatccagg cacactcctt
    16021 aattttatag ttggttggaa tagtcaaaaa cctgtacaca aaaagaccga attacaacag
    16081 gagatttcca aatgtctatc aattatattg acgcaaatct gacatcaaga ggaaaaattg
    16141 taaaaggtga aatacaaaca gtatttgaca atgaagcatc taaattaagt gcttttcaga
    16201 agatattact gacagctaat ggcacggtta cttctatgtt agaagcttac tcttctgagt
    16261 cgattcaagt agttaaactt tcggaacaat tagataatat agccctggaa ttgccaaaca
    16321 ttaaattgaa tcaacaagag caagttatgg ctagaaaagt tctgcttcag ggaaagatta
    16381 gctgtcgtaa ttttatctac gccgattcgt tgatcctgat taacaatttg ggagaaaaat
    16441 ttaggaatga attgtttaat accaataaac caatcggaca gatatggtct gagcaaaaag
    16501 ttgaaacttt taaagaaatc ataaatcatg gcaaagagtc ggctaatgaa ttagcgattt
    16561 atttcaatat taaacccgaa gaaaatgttt tttttcgcac ctattctgta tcctctcaag
    16621 gaaaaattac tatgattatt actgaaaagt ttcctgagag ctattttcac caaaagtcta
    16681 attagcatgg tagggaaaag cacaagatgt atctagataa gtattcaatt attcttcttg
    16741 acaggattta aatatgagca aaacaaacga tcccaatcaa aaaacagatt tctcaaatgc
    16801 tattggtgat ttagatattg aaatcgaatc agaaacttta aaatctgcta ctgattcagc
    16861 tattttacaa cctttggaaa taaaaattga aaagctagag ggacggcaac ggaaaatttt
    16921 tgctaaaatc cagattcctt atccattaga gcaagtttgg caagttttaa cagactatga
    16981 agggttgcct gagttcatgc ccaatatcag ccagagccga cgtttagagc atccgaccgg
    17041 aggcattcgt ctagaacaac ttcggactaa gagttttatg ggaatgaatt ttgcagtacg
    17101 ttcagttatc gacgtggaag aaaattttcc tcatgaaatt cattatcagt taatcgaggg
    17161 agatatgaaa gctttatctg cctactggcg gttaaagcct tggagtttat ctgattcaaa
    17221 agctggaatc gcgctcattt atgatttttt agttttacca aaacccattt ttccaatgcc
    17281 tttagtcgaa cacattttga gccacgatat cccagcaagt atgttagcga ttcgtcagcg
    17341 agtagaagag atttatggtt caaaataact gatttatctt aatagctatt ttaaatagtt
    17401 gcgatcgcgc tgctgctgtc ctcaaacaag ctaaagagag gggtatacat agtttgtagt
    17461 taattatact aaaaaagttc agattcaggc gatcgcaagt ttggtagaaa cagggcgctt
    17521 gaccgtctgc atttttccct aatcccctga ccaaaaaggc tttccaaaag agaacatttt
    17581 actttgcatc actgttagcg aggtttacca aaaatgaact tacatataag aacacggaat
    17641 ttcccaaagc tggtaaggca tacttttcgg aagcaagtga aacaaatttt cccatctatt
    17701 tgtggcatag cgggtttttt gactatatgg cacttactca gtctcagacc tgatacaata
    17761 ttgccttctc catttgaggt tgtaaccagt acctgggatt tgattagaga tccgtttttt
    17821 atcaagggag gtaataacaa agggtttttt tggctgattc ttgctagtct caaacgagtc
    17881 agtattggct atgttttagc tgcattagta ggaattccgg ttggtttcgt gattagtctg
    17941 agcagcttta caaaacaagc tatcgatccc atcattcagc ttttgcgtcc cgttgctcct
    18001 ctagcttggc taccaatggc tcaagccatc ttcctcaaac cagatccctc cgccatcttt
    18061 gtgatattta tcacggctat ttggccgata attcttaaca ctgctttagg tgtggaactc
    18121 gtccctaaag attatatgaa tgtctctaaa gtgttaggac tatcaattac tgagaacttt
    18181 gtcaaaattt tactacctgc tactcttccc tacatcttca cgggactaag gatagccatc
    18241 agtctttctt ggttagcagt tgttgcagca gaaatgctgc tctctgacga tggactgggc
    18301 tttttcattg tgaatgctta caacaactca gatattaatg aaatcatatt ggcagttttt
    18361 tacttgggtg gggtgggttt aatacttgac aagatgatgg cttatatatc cttcaaattg
    18421 atgccgcaga cataagcctt ttcccaatca aaaactgcaa aatataatag caatcttttg
    18481 aagaataaaa ttataaatac taagatgtac aattttgttg aaattagaag catcggtaaa
    18541 gaatttgtcg cgccggatgg tggcagaaat attgttctca aagatattaa ccttgaaatt
    18601 aagcagggag aatttgtttc tctcatcggt cattctggtt gtggtaagtc taccttgctc
    18661 aatattgtgg ctggattaga aacatctaca agaggttctg tggaagtaga tggtcaatta
    18721 gtaaggcggc caggcctgga tcgtatggtg gtgtttcaga attattcact cttaccttgg
    18781 ctaacaactt gggaaaatat agctttagct gtaaataagg caatgcctcg caaatctagg
    18841 gctgaacgcc atcagattat tgacgctcac ttagaaatgg ttggtctcaa agatgctgct
    18901 gctaaaaaac caggacaact ttctggcggg atgaagcaac gagtagcgtt ggcacgcgcg
    18961 ttagccatta agccaaaact actactgtta gatgaaccat ttggtgcatt ggatgcgcta
    19021 acccgcagtt ctttgcaagc tgagttaatg cggatctgtg acatgagcca catcacaaca
    19081 attatggtta ctcatgatgt agatgaagca ttattacttt ctgatcgagt ggtgatgatg
    19141 aacaacggac ccagtgcaac tattggtcaa attctagaga ttgcttttga acatccccgt
    19201 agtttaacag atatcgtaga ttatccagaa tatcagatat tacgccacca aatgctgcaa
    19261 tttttgtaca aacaaaagca cgaacggcaa ttggaaactg agactgcatt cactgtgcat
    19321 aaaggagttt agaaagttta aatttctatt tttttacatt ttttctacat ttaaagaaac
    19381 aagttgaaat ggcaaagctt tctagacgaa aatttttagc ctctgctgct ggtgcagcgg
    19441 ccttaaccca aactttaggt cattattcca cttctgctca aaggagtcct ggtgtttata
    19501 tcggctaccg tgatactcct gaaatcacaa ccgctaaaat aggtttcatc ccagttacca
    19561 gttgctgtcc tttaattatt gctaaagcta aaggattttt tgctaaatat ggtatgcccg
    19621 atgttgaagt tgccaagcag ccttcctggg ctgtaatgcg agacaaacta atgctgggtt
    19681 cggaaaatgg aggcttagat gggggtcatc tgctttttcc aatggcatac ttgatggcga
    19741 cgggagaaat cacctatggt cgtaaagtcc ctatgtacat cctggcgcgt ctcaatttga
    19801 atgggcaagg agtttccgta tctaatgcct ataaagattt aaaacttggt gtcaatagtt
    19861 ctccactcaa atcaatattt gctcaaaagg caaaatctgg aaaaaattta ctctgtgcta
    19921 ttccctatcg gcgggtgact ggtgattttt ttatgcgctg gtggctggct gatggtggta
    19981 ttgatcctga gcgagatgta tcactaattg ttgtgcctcc ccctcaaatg gtcgccaata
    20041 tgcgggcagg ctcaatggaa gctttctgtg tggtagatcc ttggcatcaa cggctgatca
    20101 aagagggaat tggttactcc actgttacta gtggggagtt gtggaacaat caccctgaaa
    20161 aagcacttgc cgtgcgtgct gattgggtag ataaatatcc caaggcggct aaggcgctgt
    20221 tggcagcagt gttggaggct caaatgtggt gcgaccgcgc agataataaa gaggaaatgt
    20281 ttcagattgt ctcacagcga cagtggattg gaatgaacac tgatctaatt cgcgatcgca
    20341 tcttaggtaa atttgattat ggaaacgggc gtgtgataga aaacagtcct catgctatta
    20401 aattttggcg tgaaagtgct tcctaccctt acaaaagtca tgacctgtgg tttctaattg
    20461 aagatatgcg ctgggggtat cgctcaccag aatttgaaac taaacctttg attgaggctg
    20521 taaaccgcga ggatttgtgg cgggaagcag caaaattaat aggtcaggaa aaggcaattc
    20581 cacctagtac atcacgaggt gtggagaaat ttttcaatgg tttgaaattt gatcctgaaa
    20641 atcctcaagc ttatttaatt tctactaacc tttaataata atgactaact cactgttagt
    20701 tttaaagaca agtaacttag taatttcagc agagacgctc caggagcaga gagaaagaga
    20761 tgtttgagaa acagccagaa ggtttacagc aacgggtgaa ggagttagcg aaccaagcta
    20821 tagaagaggc taatcctact gcatggtttg atgttttata tagtcagtct cagggtgatg
    20881 tgacacaaat tccttgggct aagttaactt gtcaccctta tttacaagat tggttgacta
    20941 ttcatgatac tcaaggtgag ggactttcgg cgctggtgat tgggtgtggt ttgggagatg
    21001 atgcacaagc tttagcagac aggggttttc aggttactgc ttttgatatt tcgcctacgg
    21061 ctattgattg gtgtcagcaa cgatttcctg attctgctgt gaattatgta gttgcagatt
    21121 tgttaaattt acctgcacaa tggcatcaag cttttgattt agttgtagaa attcggaata
    21181 tccaagcttt acctttgagt ctccgttcta ctgtgattgc gtcagtggct tctgtagtcg
    21241 ccgcaacggg aactttatta gtgattaatc ggtttcgaga cacagatata gaacctgatg
    21301 gacctccctg gcctttgtct gattccgaat tagcgcagtt tacagaattg ggtttgcaag
    21361 aagtcagccg tgtgcagttt tatgagggtg aacgggtgga tgttccacaa ctacgcctgg
    21421 aatatcagaa atctgtcccg ccaaaagtct aatttattac agccctggcg actagaagtc
    21481 gcggaaccac ccaaactaaa cccgcctgcg cgggttaaaa atcccatttt ttcattgtct
    21541 cgactaattc cacgccgaat acttccgcaa aacagtcagc tatattaacg cgcacttctt
    21601 cgcaggtaat accgggaatc cattcggcta aactggcgac gggtttatcc gcaataccac
    21661 aagggataat ctgtttaaag cctgacatat caggacaaac attgaatgca aatccgtgca
    21721 tagtaatcca acggctgact ttaatcccga tggcggcaac ttttcgccct tctagccaaa
    21781 ctccagtaaa acccggtagg cgatcgcctg tcaacccata aactgccaaa acccgaatta
    21841 atacctcttc taattgccgt aaataccaat gcaaatcttt acaataatat tgcagattta
    21901 aaattggata ccccacaact tgaccagggc aatgataagt tacttcgcca ccgcgttcaa
    21961 ctctgtgaac atcaaattta ctttgatcca ggtctttgag aaattcaggg ttgctgcctt
    22021 gtcccaaagt atagacaggc ggatgctcta ataatattaa cacatcatcc agactaggtt
    22081 gcagaatgcg ctcctggaga agcgatcgct gccaaaaaag cgcctctgtg tatggcatca
    22141 atccggcatt aaataacaaa caacgtctgt aatctgcttc catactacga atcatgccaa
    22201 aaatcaacag ggttattcac caaatatatt tcaatttaca gatattgagt caagaaatgt
    22261 caagcaatgc aaaggatttt aaaggaacgc caaagtcagg tgcattctag aatacaaagt
    22321 gctaagttga atatataacc tcaacggtgt taggaggaaa tctcagcatc cagcatcacg
    22381 ccaaacagaa tcagaacgaa tgcactggct ggtgaatctc ataaatcgtt tggatctcga
    22441 actggatcac ccatccaaaa cagagccaac gcataagcag tacattaaaa tagttcaaaa
    22501 tttgttttgg cggtagtgaa agaccttacc gcgacttctt ttcatacaaa acaaattcac
    22561 atcaaatata ttcagtggga gagtttacat gaagcttgtc atccacggca aaaatattga
    22621 aatcaccgat gctattcggg agtatgtaca tctaaaaatt gaaaaagccg taagtcattt
    22681 tcagaacatc accaatgaag tggatgtgca tctgagtgtc gcccgtaatc ctcgaatcac
    22741 caccaagcaa gcggcggaag tcactatttt tgcaaatggt agtgttatcc gtgcagagga
    22801 aagcagcgaa aacttatacg ccagcattga cttagtagca gataaaattg cccgtcagct
    22861 gcgtaaatat aaggaaagac ttcaagatca gaaaactaat gccccaccca caaatcaagt
    22921 attagttcct gaaccagtag cggcggattt aataggcgat cgcacccccg aattaccaaa
    22981 cgaggtcgtc cgtacaaaat atttttccat gccaccgatg accgttgcag aagccacaca
    23041 acagctgcaa ctagtgggac acgactttta tatgttccac aactctgaaa ctggcgaaat
    23101 gaatgtaatt tacgagcgta accacggcgg ttacggtgta attcaacccc gtcatagtaa
    23161 cggacacacc aacggcaaaa acggcaattc agcccaagct gtccccgcaa aagcccactc
    23221 ccataagtaa gagtcgggtc aatacttatc agataaagca gacctaaccc ccctaacccc
    23281 ccttccctac aagggaatgg gggaaactag ctcccctctc cttaacaagg gaatggggtt
    23341 aactagctcc cctctctagc tcccctctcc ttaccaagga gaggggctgg gggtgaggtt
    23401 cttttacaca gccaactgtt gcaaagtctt cagcgcttcc tcaacgtgac ccttaaaatt
    23461 caacattgaa tcaaacacat actttacaac gccctcctta tcaatcacat aagtcacacg
    23521 accagggaca aaaccaaaca ttgcagttgc gccgtattgc ttccgcactt ggtcgccttt
    23581 atcactcaag agctgaaaag gtaaattata cttctgtgca aatttctggt gagactcatt
    23641 agaatcaccg ctcacgccaa tcacctcagc gccagcagtt ttaaacacct catattgatc
    23701 ccgaaaagca caagattcgg ctttacatcc tggtgtatca tccttgggat aaaaatataa
    23761 aaccacagct ttttgaccac gaaaagcgct gaggctaact gtggaaccat tttgggcgca
    23821 aagagagaaa tcaggcgcag tatcaccaac tttaacagac atatattttc ttaccgattt
    23881 tattaagcgt caatctctgc taattctaac caccgttctg tcgcggtatc aatcgagtgc
    23941 ttgagagttt ccacttgttc atagagtttc tggacttggg tgtaattccc agcagagaca
    24001 tttaccaaag ctttttccac tgtggctttc tcagtttcca acttggcaat ttttccttct
    24061 aactcctcaa attcccgctt ttcccagttt gatagtctgc ggcgcttttt attgtcgctg
    24121 tctgaagacg aagctgcaac ttttacatct tccttgggtt tttccttcgt attcgcggct
    24181 tgttgctgtt tagcttcttc ctcctcagcc ttcttatagt cgagataaat tgagtaatta
    24241 cctggatatt tccggagatt accgccctct tccaaagcaa aaatagtatc tacagttcga
    24301 tctaaaaagt agcgatcgtg agaaactgca attacacaac caggaaaatc ttctaaataa
    24361 tcctctagta ccgccaatgt ctgcacatct aaatcattgg taggttcatc taaaatcaac
    24421 acattaggcg caccaatcag aatccgcaac aaaaacaaac ggcgtttttc cccaccagat
    24481 aacttattaa tgggcgcgta ttgctggttt ccgggaaaca gaaaccgttc taacatttga
    24541 gaagcagaaa tttgagttcc atcagagact ttgacaaatt cgccctcttc tttaatgtag
    24601 tcaatcacgc gctgattttc gtctacggct gaaagtaact cttccgaatg ctggtcaaaa
    24661 tagccgatgt gaattgtcgt tccaatatct acattaccgg aatctggttg aatacgtttg
    24721 gtaatcatat ccattaaagt agatttacca gttccattcc cgccaataat tccaatgcgg
    24781 tcttctggac taaattcgta ggtgaaatcc ttaattaaag tccgtccatc gtagccttta
    24841 gaaatgttat ttaattcaat aactttttta ccaatgcgac ggctaactgt agaaatatca
    24901 actttaccct ggacttgttt aaactcagtt tcccgcaagc tttcaacccg ttgaatccga
    24961 gctttttgtt tggtacttct ggcttttggt cctctgctta accattctaa ttctcggcgt
    25021 aatatacctt tgtgtttgcg ttggctacta attgccgatt cttcagctaa agctttcttt
    25081 tccaggtaat atgaataatt accagaataa gtgtaaatat cgcctcggtc gatttcaata
    25141 attcggtttg taacttggtc gagaaaatag cggtcgtgag ttatcagcaa aagtgcgccc
    25201 cgaaagcgat ttaaataact ttgtagccat tctacagaca gcgcatccag atggtttgta
    25261 ggttcatcca tcaataaaac atctggttct gatagtaaag ctgttgctaa agcgatacgc
    25321 ttgcgatagc ctcctgataa agtaccaata accgcatcaa aatcagaaat tcctaactta
    25381 gtcaagataa ttttggcgtt ggtttccagt tcccaagcgc cagcagtttc catgcgttgc
    25441 attaccccag acaagcggga catcaattga ctatcttctg gatggtgaac aagtttatga
    25501 gatagttctt catactcacg caccaaagcc aaatgttcac cactgtcagc aaaaatttgc
    25561 tctaaaactg tgtgattttc atctaaatct ggctgctgcg gtaaataaat tacttttgca
    25621 ccagaactaa aggtaatttg tccactatca attgattcta atccggcaat catttttaat
    25681 aaagttgact taccagaacc gttagtccca attaagccaa ctttatcggt agcatctaag
    25741 ctaaaactag catctcgtaa aagttctttg atgccaaaat cttttttaac tgattgtaat
    25801 gtaataatac tcataaaaat tagtcattgg tcattggtca ttagtcggtg tctttagaaa
    25861 atctagtttt agcaaaaaag gaacattcca gatttggcaa aaatatccgg gactcagaca
    25921 aacactgttt tacagcgctt ttgatttgaa tgaagcacag aattatctgt gtaccctgca
    25981 ccgatagcgg agccgggcgc tagccataac cactctatat ctacatctgt gttcatctgt
    26041 gtccatctgt ggttccttat ttcttgctgt acctcattta attgcaaaac gcacctgtaa
    26101 atcctcttac ctttgtatat tagcggttta ttttttcacc ctccaggata agtcacaatc
    26161 ccatcagtaa ctgctgtttg gaatgtttcc accgacaccc actaattttc agcaaataaa
    26221 tccaggggta aatgtccata catttcgttg attcccccct cattataaga ttggcaagaa
    26281 attaatacac cccgatgatg tcctgagtat gaatcgagat aacataaccc atttttgcca
    26341 tttaatttga tataaactgg cccttcgggt gtggctaaat cgctggggac ttcatagcca
    26401 aaagcatgag aataagtcct catagccagt atgccatctt ctgccgtatc agcacaaata
    26461 cctaatattt ggtaatctga aatactagct accaaagtta aagcccgacg caccaaggct
    26521 ttttctgaag gtttgagaat gggtgcgatg tctaagcagt tgaatttatg cagaattttt
    26581 gtagcttctg agattgtgag gttttggtgg tttggtgtcg tcataaatca atttatgatt
    26641 ttctgggttt ggctttggtg tctgaggtgg gttactccca cccca
//
