LOCUS       NZ_CP084681            20996 bp    DNA     linear   CON 30-APR-2024
DEFINITION  Streptomyces inhibens strain NRRL30439 chromosome, complete genome.
ACCESSION   NZ_CP084681
VERSION     NZ_CP084681.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces inhibens
  ORGANISM  Streptomyces inhibens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9696490)
  AUTHORS   Barry,C.P., Gillane,R., Talbo,G.H., Plan,M., Palfreyman,R.,
            Haber-Stuk,A.K., Power,J., Nielsen,L.K. and Marcellin,E.
  TITLE     Multi-omic characterisation of Streptomyces hygroscopicus NRRL
            30439: detailed assessment of its secondary metabolic potential
  JOURNAL   Mol Omics 18 (3), 226-236 (2022)
   PUBMED   34989730
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9696490)
  AUTHORS   Barry,C.P., Palfreyman,R. and Marcellin,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2021) EMS, Australian Institute for Bioengineering
            and Nanotechnology, Cnr College Rd & Cooper Rd, Brisbane, Queensland
            4103, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. APRIL-2018
            Assembly Name                     :: AIBN_shyg
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 239.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022221585.1-RS_2024_04_30
            Annotation Date                   :: 04/30/2024 04:58:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,775
            CDSs (total)                      :: 8,682
            Genes (coding)                    :: 8,305
            CDSs (with protein)               :: 8,305
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 377
            CDSs (without protein)            :: 377
            Pseudo Genes (ambiguous residues) :: 0 of 377
            Pseudo Genes (frameshifted)       :: 158 of 377
            Pseudo Genes (incomplete)         :: 310 of 377
            Pseudo Genes (internal stop)      :: 38 of 377
            Pseudo Genes (multiple problems)  :: 116 of 377
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:32:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6272937
            Orig. end                         :: 6293933
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084681.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Australian Institute for
            Bioengineering and Nanotechnology, Building 75,Cnr College Rd &
            Cooper Rd, Brisbane City QLD 4072.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20996
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20996
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20996
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10996](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10996
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(548..1186)
                     /locus_tag="KI385_RS28545"
                     /old_locus_tag="KI385_28610"
     CDS             complement(548..1186)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009717816.1"
                     /locus_tag="KI385_RS28545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28610"
                     /product="response regulator transcription factor"
                     /protein_id="WP_281066917.1"
                     /transl_table=11
                     /translation="MGAEQAATVRVLLADDHPVVREGLCAMLESDPGIEVVGQAGSGEE
                     AVTLVGRLAPDVVLLDLRMGGLDGVGATGQILRRSPGTKVVIVTTYEEDSDILRAVEAG
                     AAGYLLKGSSRAELIGAVHAAARGETVLTPSLATKLFRARAVEAPLLSGRECEVLRLVG
                     QGLTNAEIGRELFIGEATVKTHLLRAFKKLEVSDRTAAVMTAWERGLLS"
     gene            complement(1176..2486)
                     /locus_tag="KI385_RS44015"
     CDS             complement(1176..2486)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089250.1"
                     /locus_tag="KI385_RS44015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sensor histidine kinase"
                     /protein_id="WP_281066918.1"
                     /transl_table=11
                     /translation="MVEAGVGRAAEARVRWFGLWDSYFVICYLVTTGLVFTSGVPQSHR
                     VIAIGALTLAVPWYAGVGRPLMLRHDSDRRNVVFPVGLFVLFVVAGAVDLMSSFALFAI
                     VPMVMMSLATRPAIVVAGLGNLVPVTMLWWQGGTASPAVLSVLLASLLGIALSVLLGLW
                     IKRVVRQNKEHAELIEELRKNREQMARLSHEAGIAAERERLAREIHDTLAQSLTSIIGL
                     VQAAESEVEGAPGLDRARKHLALAGRAAKEGLVEARDFVAARTPASLRESSLAQTVRRQ
                     TDALTAQTGLPVRFAVEGDEQPLPMAVSVVLLRGAQETLANIRKHAAARRVVVTLRYAG
                     SHVALVVTDDGEGFDAAAGEDAGEDDRDGGFGLRGLRARVAEIGGVTAVSSGRGEGTTV
                     EVKVPLVEAPRAEAPPAEAPRVEASLGHAAEGASHGR"
     misc_feature    2619..2632
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.92"
                     /tool="antismash"
     misc_feature    complement(2621..2634)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.73"
                     /tool="antismash"
     misc_feature    2622..2635
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.01"
                     /tool="antismash"
     gene            2650..3201
                     /locus_tag="KI385_RS28555"
                     /old_locus_tag="KI385_28620"
     CDS             2650..3201
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089251.1"
                     /locus_tag="KI385_RS28555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28620"
                     /product="hypothetical protein"
                     /protein_id="WP_238575018.1"
                     /transl_table=11
                     /translation="MSHLSQFVIALIASGTILTIILATDLGHRRLTNMRMLRSVIAVAL
                     IIAIFVRSFPTSGNAPSFQLIGLGVGVICGLVAGALLPAHRGTDGRIYTTGGFGYALVW
                     IVLSSARVLFAYGAEHWFTDDLIRFSIENELSGPDVYANAFVFMSLAMVLTRTAVLVTK
                     RHRIRNAEANARGTEQPAAI"
     gene            complement(4277..>4414)
                     /locus_tag="KI385_RS28560"
                     /old_locus_tag="KI385_28625"
                     /pseudo=""
     CDS             complement(4277..>4414)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655150.1"
                     /locus_tag="KI385_RS28560"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28625"
                     /product="flavoprotein"
                     /pseudo=""
                     /transl_table=11
                     /translation="LRAMRVHVLYGEGGFVPNELGQGRPDAYPWHLALEAAEQAANARS
                     "
     misc_feature    4695..4708
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.76"
                     /tool="antismash"
     gene            4722..5477
                     /locus_tag="KI385_RS28565"
                     /old_locus_tag="KI385_28630"
     CDS             4722..5477
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605867.1"
                     /locus_tag="KI385_RS28565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28630"
                     /product="DUF4239 domain-containing protein"
                     /protein_id="WP_238575019.1"
                     /transl_table=11
                     /translation="MLLAGLVVGIAGGTAIIQAFVRHRFPRLKQGEHNEVAQFLFPVIA
                     VVYGFLIGFIVLALWGQVNSADQTTRTEGAAAVQMARARNVFGTAESARIRQSLMEYGR
                     AAAAEWPHAARGNTTPEAENALNRLHSTYENIKPRSDTQRAFLASSLASLRELDLARTG
                     RLLEARSNVGPPLSLWMVIFLTTGLVLGFSVVFGSEQAQMHYGMVGAVSVLVAANLFLV
                     TELSYPFLGEFSTSPEPLNAVVNVLSSPH"
     gene            complement(5512..6738)
                     /locus_tag="KI385_RS28570"
                     /old_locus_tag="KI385_28635"
     CDS             complement(5512..6738)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058533.1"
                     /locus_tag="KI385_RS28570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28635"
                     /product="transposase"
                     /protein_id="WP_238577886.1"
                     /transl_table=11
                     /translation="MSPAGVRAADDQAHAARTMWNLLHAWWRMMPKEMRTLANADAAIR
                     QAREDIDFLAALPAQAAQAVLKTYFRAWKNCWEGRADAPNFKGRFRTVMSVDIPQGRDL
                     NITRVHRRWGMVNIPKVGRVRFRWTKDLPVGKRANANNRITGARLIKDALGWHIAFRVQ
                     TLEVKPDPHQGPDVGIDVGVTVPIALSDGETYEHGEWLTGKEKARLLHLEQRAAQRKQH
                     RKPGERTSRRLHRTYDQIAGLRAKAKRRALDWQHQTTTVIARTYGTVVVEALTITNMVK
                     SARGTIEEPGKNVAQKSGLNRSISGEAWGRTVTMLTYKTAQLGGTLHKVPAPGTSRRCS
                     ACGFTTPGNRESQAVFVCKNPDCGWSGNADHNAARNVLHLYRMGLALIPAAGRAVVRRA
                     KRVKPAAAR"
     gene            6817..7245
                     /gene="tnpA"
                     /locus_tag="KI385_RS28575"
                     /old_locus_tag="KI385_28640"
     CDS             6817..7245
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tnpA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058534.1"
                     /locus_tag="KI385_RS28575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28640"
                     /product="IS200/IS605 family transposase"
                     /protein_id="WP_238575020.1"
                     /transl_table=11
                     /translation="MSPRWNPNPDVRTGRHVVHNLHVHLVFVTKYRRKAFTDAMLTRTE
                     EIMREVCDDFEAELKQFNGEQDHVHLLVHYPPKVQLSKLVNSLKGVSSRRLRQEYDSHV
                     RRYLWGGHFWSGSYFAGSCGGAPLTVVKQYIENQQRPV"
     gene            8072..9730
                     /locus_tag="KI385_RS28580"
                     /old_locus_tag="KI385_28645"
     CDS             8072..9730
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF018884.4"
                     /locus_tag="KI385_RS28580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28645"
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_238575021.1"
                     /transl_table=11
                     /translation="MRTAVFREDESNPGAFQANASIVQAGFFFWEISTGEVSCDPLTLA
                     LHGMPENGPSDISSFLAAVHESDLADVRDALGLIAESCGNYQIEYRVTSDDGHRSLEAR
                     GRVLPGADGLPARMVGVVMDTTAVHERHEAERRRLYERATRDRWMQELTAALAAAVTVK
                     DIMAAAQAGLRTFGAGALAVIAPEGDQLAVVASCADDEQGEDSMRVLDATVRTLVEESL
                     DRRAPVLIGSADALITGYPHLAPLEQSARQAWAALPLTDSRGRVSSCLVSFPEPQEFLP
                     EERALLVAAMGLLAQSLERAGMYESEHALATELQRGMLPRGPLTVPGVTIAARYQAATS
                     GMWIGGDWYDAISLPDGGVALVIGDVQGHSVHAASLMGRLRTAVHAYANEGHPPAAVLE
                     RTNRLLAELNTDPDRALFATCCYIALTPSDGRLQVCRAGHPAPALITPRKPPRLLEVPG
                     GLPLGIDREQRYPTTRLRIAPGSVLALTTDGLLEAVNKDIDQGFERFLRGLRGAPTADL
                     ETVVDALLAGTQKAHGLGDDVALLLARLNKPDRRS"
     gene            10001..10996
                     /locus_tag="KI385_RS28585"
                     /old_locus_tag="KI385_28650"
     CDS             10001..10996
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="KI385_RS28585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28650"
                     /product="hypothetical protein"
                     /protein_id="WP_238575022.1"
                     /sec_met_domain="T1TS (E-value: 5.9e-63, bitscore: 212.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENFRIPDLYIPVLAALNPELQEAAAAAEAWLDEFGLVPTEEARR
                     HVQRTRVDRLTAWLCPNASQEALTLITQWNAWLFQLDDQFDDDPVRGYQPEQWRDAFGP
                     LFAVFDGNVTTGRLARSLADLWRRTVAVRSSAWQRRFVPHLLWYFDSYRADMIHREEGR
                     VPGLQQYLAHRRASFAFDAVLDLMEIGIGVDLPDQLHANPAFADMREAVIYANACINDL
                     YSLPKELAHDYAFNAVAVICHHHRCSLQEAAERVAVMQAGYVQRILDLEQVLPGRLARS
                     GLADDVIVDALRCVRDFHALTAGNVAWSKETGRYAEVEAKPTYLADLFIP"
     gene            complement(11102..11809)
                     /gene="msrA"
                     /locus_tag="KI385_RS28590"
                     /old_locus_tag="KI385_28655"
     CDS             complement(11102..11809)
                     /EC_number="1.8.4.11"
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603491.1"
                     /locus_tag="KI385_RS28590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28655"
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="WP_238575023.1"
                     /transl_table=11
                     /translation="MLFSRFKTHLPTPEEALEGRPERAFTVPARHTVLGNPLLGPYPDG
                     LETADFGLGCFWGAERKFWQAEGVWTTLVGYQGGHTPHPTYEEVCSGHTGHTEAVRVVY
                     DPAVVPYTSLLKLFWESHDPTQGFRQGNDVGTQYRSAIYTHSPAQQQAAEASRDAYRTV
                     LHNSGYADITTEILPADSRPFYPAEGYHQQYLDKNPAGYCGIGGTGVKLSTPFETNWGA
                     SCPTGLAPAPTEE"
     gene            complement(11945..13075)
                     /locus_tag="KI385_RS28595"
                     /old_locus_tag="KI385_28660"
     CDS             complement(11945..13075)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089262.1"
                     /locus_tag="KI385_RS28595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28660"
                     /product="hypothetical protein"
                     /protein_id="WP_238575024.1"
                     /transl_table=11
                     /translation="MDALLVLLAALTLGGFVFLPWMRRRRAVQHTRQGLVVATDPMAGY
                     GFVPLEQLDVRLPGPDQELDEALAEMRRTHDWRPAAELLKSTGDDWERRWQRVQTLAGA
                     AAFELAEGGTEQGGGGRTGGIWLRTWRSEAPKDPGGAQTHAQFLVVQALRDPGSQDFRM
                     ILEEARTVCREAALLAPGSPIPYITELAVARGLGDRPADYEELWSKVAQRAPQHMGAHL
                     AALPYWSQKWHGSRTEAEAFAERAAAAAPAGTLLPALPLFAVYEHLPEANMVRSLYQSA
                     VVERAIEGAHFALREAPADHPMAPHVRHLLVWFLVRAERYAEAMEQLRLVDGHVGAVPW
                     SYGRSPAAEYAAYRALAIAGWEQLGGTSAGFPPPGK"
     misc_feature    13183..13201
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.28"
                     /tool="antismash"
     misc_feature    complement(13212..13226)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.62"
                     /tool="antismash"
     gene            13281..14441
                     /locus_tag="KI385_RS28600"
                     /old_locus_tag="KI385_28665"
     CDS             13281..14441
                     /EC_number="2.5.1.48"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (58-223). E-value:
                     6.1e-11. Score: 33.9. Matches aSDomain:
                     nrpspksdomains_KI385_RS28600_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981943.1"
                     /locus_tag="KI385_RS28600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28665"
                     /product="cystathionine gamma-synthase"
                     /protein_id="WP_238575025.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.8e-09,
                     bitscore: 36.3, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9e-09, bitscore:
                     33.9, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 6.3e-06, bitscore:
                     24.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQRDQRPQHFETRAIHAGQEPDQATGAVVPPIYQVSTYKQDGV
                     GGLRGGYEYSRSANPTRTALEENLAALDGGRRGLAFASGLAAEDCLLRTLLTPGDHVVI
                     PNDAYGGTFRLFAKVVERWGVEWSVADTSDPQAVREALRPRTKVIWVETPSNPLLGISD
                     IAALAGIAREAGARLVVDNTFASPYLQQPLALGADVVVYSTTKYMGGHSDVVGGALVVN
                     DDTLGEELAYHQNAMGAIAGPFDAWLVMRGIKTLAVRMDRHSANAARIAELLVSHKKVT
                     RVYYPGLSEHPGHEIAAKQMRSFGGMVSFQVAGGEQAAVEVCNRAGLFTLGESLGGVES
                     LIEHPGRMTHASTAGSALEVPNDLVRLSVGIESVDDLLADLTQALG"
     aSDomain        13455..13949
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KI385_RS28600_Aminotran_1_2.1"
                     /evalue="6.10E-11"
                     /label="KI385_RS28600_Aminotran_1_2.1"
                     /locus_tag="KI385_RS28600"
                     /protein_end="223"
                     /protein_start="58"
                     /score="33.9"
                     /tool="antismash"
                     /translation="NPTRTALEENLAALDGGRRGLAFASGLAAEDCLLRTLLTPGDHVV
                     IPNDAYGGTFRLFAKVVERWGVEWSVADTSDPQAVREALRPRTKVIWVETPSNPLLGIS
                     DIAALAGIAREAGARLVVDNTFASPYLQQPLALGADVVVYSTTKYMGGHSDVVGGALVV
                     ND"
     gene            complement(14463..14711)
                     /locus_tag="KI385_RS28605"
                     /old_locus_tag="KI385_28670"
     CDS             complement(14463..14711)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007458374.1"
                     /locus_tag="KI385_RS28605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28670"
                     /product="hypothetical protein"
                     /protein_id="WP_238575026.1"
                     /transl_table=11
                     /translation="MSLPDRKETEVRRMLAGPHPLVPPDLAVRAAARGRRRKAHRRVLR
                     RIGWLLALLALTALAWAVVAQPWTPPPVRTTPPVEGW"
     gene            complement(14708..15172)
                     /locus_tag="KI385_RS28610"
                     /old_locus_tag="KI385_28675"
     CDS             complement(14708..15172)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541793.1"
                     /locus_tag="KI385_RS28610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28675"
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_238575027.1"
                     /transl_table=11
                     /translation="MRERRLAQERRHAREFEVFVAGAAGRLLHTAALLTGEPVSRPAPA
                     AEELLTCALSRTYAVWDRLRGEDPYERTRQEMAAHFAHTAWRHRRPRGGLLDRLSPQER
                     LVLVLRLYEGVAEEQTAAQLGLPTERVHALCLRALAEMRSRRPEPKPAAP"
     gene            complement(15347..15847)
                     /locus_tag="KI385_RS28615"
                     /old_locus_tag="KI385_28680"
     CDS             complement(15347..15847)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006603484.1"
                     /locus_tag="KI385_RS28615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28680"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_128510058.1"
                     /transl_table=11
                     /translation="MPTSSDMTTHTDPALLDALQHQVAVFARRAEQSRLGGVGQARNSM
                     DRAAYLLLNRLDQEGPMGVKALAAGMGIDSSTVTRQVAPLVDSGLVSRATHPEDGRAVV
                     LQLSERGHARLDEVRASRRALMALVTDEWSEEEREAFTTLLTRFNASLADITASLTPAG
                     PTS"
     gene            16163..17362
                     /gene="ilvA"
                     /locus_tag="KI385_RS28620"
                     /old_locus_tag="KI385_28685"
     CDS             16163..17362
                     /EC_number="4.3.1.19"
                     /GO_function="GO:0004794 - threonine deaminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006549 - isoleucine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118470.1"
                     /locus_tag="KI385_RS28620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28685"
                     /product="threonine ammonia-lyase"
                     /protein_id="WP_238577887.1"
                     /sec_met_domain="PALP (E-value: 1.1e-83, bitscore: 280.0,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITVDEVREAHKMLSGVSRATAMEGSRYLSGLVGSPVHLKCENLQ
                     RTGSFKIRGAYVRIAGLSAQERAAGVVAASAGNHAQGVALAASLLGVRSTVFMPVGAPL
                     PKVAATRDYGAEVRLHGQVVDETLAAAQEYARETGAVFIHPFDHRDIIAGQGTVGLEIL
                     EQCPEVRTIVVGIGGGGLASGIALAVKALRPDVKVIGVQAAGAACYPPSLAAGRPLAIE
                     GLSTMADGIKVGRPGDVTFGIVEELVDEVRTVTEDQLSSALLLCLERAKLVVEPAGASP
                     VAALLADPGHFEGPVVAVLSGGNVDPLLMQRILRHGMAAGGRYLSLRLRLTDRPGALAM
                     LLGVLSVVDANVVDVGHVRTDPQLGLTEVEVELHLETKGPEHCDEVRAALGEAGYVVAE
                     "
     misc_feature    17449..17462
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.78"
                     /tool="antismash"
     gene            17648..18766
                     /locus_tag="KI385_RS28625"
                     /old_locus_tag="KI385_28690"
     CDS             17648..18766
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089266.1"
                     /locus_tag="KI385_RS28625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28690"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_238575028.1"
                     /transl_table=11
                     /translation="MPGAIYAEGLVKTFGDVRALDGVDLDVPEGTVLGMLGPNGAGKTT
                     AVRVLTTLLQPDRGKAVVAGIDVLAHPDQVRRSIGLSGQFAAVDEYLTGRENLVMVGQL
                     YQMSGRDAKRRAAELLERFNLGDAADRTAKTYSGGMRRRLDLAAALVVSPPVMFMDEPT
                     TGLDPRNRQALWDVIQELVAGGTTLLLTTQYLEEADRLAHDICVVDHGKVIARGTSDQL
                     KARTGGERVEVVVHAPEHLSIADEVLRGFGKGEGTIEPHIRKLTIPVTGGAKLLAEVIR
                     ELDTRGVEIDDIGLRRPTLDDVFISLTGHAAEADENGANGKNGGKGGGGAVGRQKKGRK
                     GAEPGEPVAPSGAAAAAEAVDAGVTTNKEGVK"
     gene            18763..19644
                     /locus_tag="KI385_RS28630"
                     /old_locus_tag="KI385_28695"
     CDS             18763..19644
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089267.1"
                     /locus_tag="KI385_RS28630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28695"
                     /product="ABC transporter permease"
                     /protein_id="WP_238575029.1"
                     /transl_table=11
                     /translation="MTTVTRTAGGDARIRTPQSRGGLGRSIRDSLVVAKRNLIRMIRIP
                     EVVIFGLIQPIMFVVLFTYVFGGSINIPGAPAGDAEAYHEFLMAGIFAQTVTFATAGAG
                     AGIADDMHKGLIDRFRSLPMSRGAVLTGRTLADLVQTALTLVVLAVVALLIGWRTHENI
                     AGVLAGFALLLLLGYAFSWIGALIGLSVRTPEAATSGGLIWLFPLTFISNAFVPVNGMP
                     AFLQHVAEWNPFSATVAAARELFGNSIDRVPKSVTGAWPMEHPVLASVIWSVLIIAFFR
                     TLAVRKYRSATA"
     gene            complement(19745..20242)
                     /gene="greA"
                     /locus_tag="KI385_RS28635"
                     /old_locus_tag="KI385_28700"
     CDS             complement(19745..20242)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0070063 - RNA polymerase binding [Evidence
                     IEA]"
                     /GO_process="GO:0032784 - regulation of DNA-templated
                     transcription elongation [Evidence IEA]"
                     /codon_start=1
                     /gene="greA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645222.1"
                     /locus_tag="KI385_RS28635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28700"
                     /product="transcription elongation factor GreA"
                     /protein_id="WP_128510056.1"
                     /transl_table=11
                     /translation="MTQTSENVTWLTQEAYDQLKAELEHLSGPARAEITEKIAAAREEG
                     DLKENAGYHAAKEEQGKQELRVRQLTQLLQSAKVGEAPAATGVVAPGMVVTIAFDGDPD
                     DTLSFLLASREYASSDIETYSPQSPLGTGVNGKKVGAAAEYELPNGKKASVKILDAKPY
                     TG"
     misc_feature    complement(20349..20363)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.39"
                     /tool="antismash"
     gene            complement(20482..20892)
                     /locus_tag="KI385_RS28640"
                     /old_locus_tag="KI385_28705"
     CDS             complement(20482..20892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089269.1"
                     /locus_tag="KI385_RS28640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_28705"
                     /product="DUF4307 domain-containing protein"
                     /protein_id="WP_238575030.1"
                     /transl_table=11
                     /translation="MTAVREGLPDGRYGRSADQRADRKLKIVGSVLGVALLGVIGWAGV
                     SYITGQDLSGRVITWDAVSDHAVKVHLEVVKGTDDKGVCTLRSQSADGSEVGRKDVTID
                     RRADQVDTEVTVRTTKRATNAVLVGCTVSGSR"
ORIGIN
        1 tttcgctttt cgctcgccgc tttccgtccg gcgaacctcc ggccatctgg ggcagtgcgg
       61 gggtaacacg taacgggcaa cgctcggtta cgcccggcgc acaggtcagc gttgagtaat
      121 gcgtatgcgg ccgtcaaggc cacgatcggg aaacctcatc gccaaggaat ggccgaaatc
      181 caggcccggc cggagatggg caaattcgtt tcttctcttc tccggtgcgt tcctggcgcc
      241 ggaccggacg ggggcgacgg cgctacggcg accgaaagcc gatgaagaag acacgggctc
      301 accaccacgg actttgcccc gagttcgagc ccattcggac aacggcctcc ccgtgtacgg
      361 gccgatcacc agccgtccgc ccggcgccac cgccgtggtg agcagatgcc gcaccaggag
      421 ctcggcacgg acgacggtga gcgcatcgct gtccgacctc cggaaggtga ctgctctcaa
      481 ggggtgcgcg ggcgcaggag gggcgtcaca gggagagggg cggccggggc ggcgcggctc
      541 ccgggcgcta ggacaacaac ccgcgctccc acgccgtcat cacggccgcg gtccggtccg
      601 acacctccag tttcttgaac gcgcgcagca ggtgcgtctt gaccgtggcc tcaccgatga
      661 acagctcccg gccgatctcc gcattggtca gaccctggcc gaccagccgc agcacctcgc
      721 actcccggcc ggacagcagc ggcgcctcca ccgcccgcgc ccggaacagc ttggtggcca
      781 gcgacggcgt cagcaccgtc tcaccgcgcg ccgcagcgtg caccgcgccg atcagctccg
      841 cccgggaact gcccttgagg agatagcccg ccgcgcccgc ctccacggcg cgcaggatgt
      901 cggagtcctc ctcgtaggtg gtgacgatca cgaccttggt gcctggcgac cgccgaagga
      961 tctgcccggt cgcgccgacc ccgtccagcc cgcccatccg cagatcgagc agcacgacgt
     1021 ccggagcgag ccggcccacc agcgtcacgg cctcttcacc ggagcccgcc tgcccgacga
     1081 cctcgatccc cgggtcggac tccagcatcg cgcagagccc ctcacggacg acgggatggt
     1141 catcggccag cagcaccctg accgtggccg cctgctcagc gcccatggct cgccccctcc
     1201 gccgcatggc ccagggacgc ctccacccgg ggcgcctccg ccgggggcgc ctccgcccgg
     1261 ggcgcttcca ccaggggaac cttcacttcg acggtggtcc cctccccccg tccactgctg
     1321 accgccgtca ccccgccgat ctccgccact cgtgcccgca agccacgcaa cccgaagccc
     1381 ccatcccgat cgtcttcccc cgcatcctct cccgcggccg cgtcgaaacc ctcgccgtca
     1441 tcggtgacga cgagagcgac atgactcccg gcgtaccgga gcgtgaccac caccctgcgg
     1501 gcggcggcat gcttgcggat gttcgcgagg gtctcttgcg cgccgcgcag caggacgacg
     1561 ctgaccgcca tcggcagggg ctgttcgtcc ccctcgacgg cgaaccgcac cggcagcccc
     1621 gtctgggcgg tcagagcgtc cgtctgccgc cgtacggtct gggccagcga gctctcccgc
     1681 agcgaagcgg gcgtccgggc ggccacaaaa tcgcgcgcct cgaccaggcc ctccttggcc
     1741 gcccgcccgg ccagcgccag gtgtttgcgg gcacggtcca ggcccggggc tccctccacc
     1801 tccgattcgg cggcctgaac gaggccgatg atgctggtca ggctctgcgc cagggtgtcg
     1861 tgaatctccc gcgccagccg ctcgcgttcg gcggcgatgc cggcctcgtg cgacagccga
     1921 gccatctgtt cgcggttctt ccggagctct tcgatcagct cggcgtgttc cttgttctgc
     1981 cgcaccaccc gcttgatcca cagcccgagg agtacggaca gcgcgatccc gagcagcgag
     2041 gcgagcagca cggacagcac agccggggac gcggtgccgc cctgccacca cagcatcgtc
     2101 acggggacga gattgccgag cccggcgacc acgatggccg gcctggtcgc caggctcatc
     2161 atcaccatcg ggacgatggc gaacagggcg aaggaactca tcagatcgac cgcgccggcc
     2221 acgacgaaga gcacgaagag gccgacgggg aagacgacgt tccgccggtc gctgtcgtgg
     2281 cgcagcatca gcggccgccc gacgcccgcg taccagggca cggccagcgt cagcgcgccg
     2341 atggcgatga cacggtgact ctgcgggacc ccggacgtga acaccagccc cgtggtgacc
     2401 agatagcaga tcacgaagta gctgtcccac agcccgaacc accgcacccg cgcctcggcc
     2461 gcgcgcccca ccccagcctc caccatgccc ctgtcctatc acccgccccc caccgccgcg
     2521 ctgtccaccg accggtggac acccgaatcc accggtcggt cgtcccgcga caaagtcccg
     2581 ccgccataac gtcgttgagg acatgccgcg gacgccgcgg ttttcgtaaa aagaaaggcc
     2641 cggctgccga tgagccacct gagtcagttc gtcatcgcac tcattgcgag cggaacaatc
     2701 ctcaccatca tcctcgcgac cgacctgggc caccgccggc tcaccaatat gcggatgctg
     2761 cgttccgtga tcgcggtcgc cctcatcatc gcaatcttcg tgcgctcctt cccgacttcc
     2821 gggaacgcgc cgtcgttcca gctcatcggc ctcggcgtgg gcgtgatctg cggcctggtg
     2881 gccggcgcac tgctccccgc acaccgcggc accgacggcc ggatctacac caccggcgga
     2941 ttcggatatg ccctcgtctg gatcgtcctc tccagcgccc gggtcctttt cgcctacgga
     3001 gccgagcact ggttcaccga cgacctgatc cgcttcagca tcgagaacga actcagcggc
     3061 ccggacgtct acgcaaatgc ctttgtcttc atgtcacttg ccatggtcct cacccgcacc
     3121 gcggtcctcg tgacaaagcg ccaccgaatc cgcaatgcgg aggcgaatgc gaggggcacg
     3181 gaacagcctg ctgcgatctg acggccattc atctgcggcc tgacggtcat tcatccatcg
     3241 gccggagacg gtgtaagcgg tccaggtcgc cggcgagcag gtcgtcgtgc gtgagggtga
     3301 agtcgccgtt ggccagcgtg gccgcttgtg ccgcggtacg tccccgagcg cagctgggat
     3361 ctgggtcgga tcggctgcca gcagcacggt gtagatgtcg tgttcgaaga cctcgacctg
     3421 cgaatcctcc cagctcatcc atgcgatgtc gtcaggcatg cccaccggga cgggtcggac
     3481 cgcgtcgacc atgcggtgga ggacatcgcc ggtgcgcccc accgggatga agtgctcccg
     3541 cgtcatgcgc gaggcggagt ggcgtcgaag caggtcagca acggactact ggtcgatccg
     3601 caacgagcac gaatccgcct atctacgctg ctgtccagcc aaggaggggc agcacgtaca
     3661 gacggcggga gcagacccaa caaaatgcag gtcatggcaa cctcgggggc ggcaggaaaa
     3721 gggcttggtg gtctgggcaa gtagtggggg gtcttaagtg gccttctgct gatcgccgcg
     3781 tggatcaacc atgcggcagg accaatcgtg gtgatcgtgc tctcagcagt cactaccgcg
     3841 tggtgcttct tccgagcccc tgttacgtgt ggtgctccgg tccgagggcg agatgacggc
     3901 tgccggaaca acgcttcggg acttctcatg ggatgtccgc aggtccgcca gcaccgctgg
     3961 cagaaactta agctacgcgc cttctgctca ggcctgttct cggatggcaa ggccaccatc
     4021 gtcacgctcg caggcgtagg gagctttgtc tccggcctcg tcgcgcttgt cccaggcgtc
     4081 gtcgtccact gaccggccga gcgaagcacg tggcaacaca acccggtagg gacgggcgtc
     4141 aagctaagtg acccatctgg ggagagctgg ggcgggactg ccctacggca atcgcacgcc
     4201 gactgatggc tgagagcgcc tgcgcggctg cttgatccac gtcaagccgt ggtgggggcc
     4261 tctggttcct gggccgtcag gaccgggcgt tcgccgcctg ctcggcggcc tccaaggcga
     4321 ggtgccatgg ataggcatcc ggtcgcccct ggcccagctc gttgggtacg aacccaccct
     4381 cgccgtacag aacgtgcacc ctcatggcgc gcagggtctc gcggggcccg gccaacaatc
     4441 ccgggccccg gggcacaccg gctgatccac agaggcctct cctcttctga gctgaacacc
     4501 tccgttgcgt cccgggcgag cccccgtccc gtgccgggtg gatgccgatc atgtgcggtc
     4561 gtctcgcgcc gaagatgcgg tcatctcgcg ctgaagagac gaagagggcg tgtccacaga
     4621 ccggggcttt cgttggccac cgcgccggtg gtggcgggtg tggggtatgt caggagcgtg
     4681 gagcggtgac ccgttggatc gtgatcaacc tcccttcctg gttgctgctg gcagggctcg
     4741 tcgtcggtat cgccggcggg acagcaatca tccaggcgtt tgtccggcac cgattccctc
     4801 gcctcaagca aggcgagcac aacgaggtcg cacagttcct cttccctgtt atcgctgttg
     4861 tctacgggtt cctcatcggc ttcatcgtcc tcgcgctctg gggccaggtg aactcggcag
     4921 accagacgac gcggaccgag ggcgccgcgg cggtgcagat ggccagggcc cgcaatgtgt
     4981 tcggcacggc cgagagcgca cggatccggc agagcctgat ggagtacgga cgcgcggcgg
     5041 cggccgagtg gccccacgcc gcgcgcggca ataccacgcc cgaggcggag aacgcgctga
     5101 accgcctgca cagcacgtac gagaacatca agccccgcag cgatacccaa cgagccttcc
     5161 tcgccagctc gctcgcgtcc ctgagggaat tggatctcgc acgaacggga cggctgcttg
     5221 aggcacgcag taacgtcggc ccacccctgt ccttgtggat ggtgatcttt ctgaccactg
     5281 gactggtcct cgggttctcc gtcgtcttcg gctccgagca ggctcagatg cactacggga
     5341 tggtcggggc ggtgagcgtc ctcgttgccg ccaacctgtt cctcgtcaca gaactgtcct
     5401 atcccttcct cggtgagttc tccacgtcac cggagccact gaacgcggtg gtcaacgtcc
     5461 tgtcgtcgcc tcattgaagt gctcttccgg ctgaagccgg gagattcctg cttaccttgc
     5521 ggcagcgggc ttgacgcgct tcgcgcgcct gacgactgcc ctcccggcag ccgggatgag
     5581 cgcgaggccc atccggtaca ggtgcaagac gttccgggct gcgttgtggt cggcgttgcc
     5641 cgaccagccg cagtccgggt tcttgcacac gaacacggcc tggctctccc ggttgccggg
     5701 cgtggtgaag ccgcacgccg agcagcgcct ggaggtgccg ggggcgggga ccttgtgcag
     5761 ggtgccgccg agctgggcgg tcttgtacgt cagcatggtg accgtccggc cccatgcctc
     5821 cccgctgatg gagcggttca gcccagactt ctgggcgacg ttcttccccg gctcctcgat
     5881 ggttcccctg gccgacttga ccatgttcgt gatggtgagc gcttcgacca cgacggtgcc
     5941 gtatgtgcgg gcgatgacgg tggtcgtctg gtgctgccag tccaaggccc ggcgcttggc
     6001 tttcgcgcgg agtcctgcga tctggtcgta ggtgcggtgc agccggcggc tggtgcgctc
     6061 gccgggcttg cggtgctgct tacgctgcgc ggcgcgctgc tccaggtgca aaagcctggc
     6121 cttctccttg ccggtcagcc attcgccatg ctcgtacgtt tcgccgtccg agagggctat
     6181 gggcacggtg acacccacgt cgatgccgac gtccggcccc tggtggggat cgggcttgac
     6241 ctccaaggtc tgaacacgga aggcgatgtg ccagccgagc gcgtccttga tcagtcgtgc
     6301 cccggtgatc cggttgttcg cattggcacg cttgccgacc ggaaggtctt tggtccaccg
     6361 gaagcggacc cggcccacct tgggaatgtt gaccatgccc cagcggcggt gcacgcgggt
     6421 gatgttcagg tcgcggccct gcgggatgtc cacggacatc accgtgcgga accggccctt
     6481 gaagttcggg gcgtcggcgc ggccctccca gcagttcttc cacgcccgga agtacgtctt
     6541 gagtaccgct tgcgcggcct gggcggggag ggcggccagg aagtcgatgt cctcgcgggc
     6601 ctgtcggatc gcggcgtccg cgttcgcaag agtccgcatt tccttcggca tcatccgcca
     6661 ccacgcgtgg agaagattcc acatcgtgcg ggccgcgtgc gcctgatcat ccgccgcgcg
     6721 aaccccggca ggagacagcg aaagccgggc acggtgcccg aactgtcgct tgaccagggc
     6781 gtcttgactc acgaccgaga aacataatat tggtttatgt caccgcgctg gaatcctaat
     6841 cccgacgtac gcaccggacg tcacgtcgtc cacaacctgc atgttcactt ggtttttgtc
     6901 acgaagtacc ggcggaaggc gttcaccgac gccatgctga cccgcaccga agagatcatg
     6961 cgggaggtct gcgacgactt cgaggccgaa ctgaaacagt tcaacggcga acaggaccac
     7021 gtccacctgc tcgtgcacta cccgcccaaa gtccagctct ccaagctggt caactccctc
     7081 aagggcgtca gctcccgcag gctccgccag gagtacgaca gccacgtccg ccggtacctg
     7141 tggggcggac acttctggtc cggttcctac ttcgcaggat catgcggcgg ggcacccctg
     7201 accgtcgtca agcagtacat cgaaaaccag cagcgtcccg tctgaccgtc accccggagc
     7261 cgcagagcgc tccggcgctc cgcgcctccg gaccaaggat gaccttcacc cccgccctga
     7321 agggcggagc actggccaag atcagaggta gaccggaggg cggggtgcgg ccggcggcca
     7381 tgccgctgcc gaggcctgat cgctccgaag ctctgagctc gggaattacg gggtcatccg
     7441 tgccaagcgg ggcgttcgcc cctacgccct gctccggcca agattcccaa ggtcagtcct
     7501 cgacgggcgc gatccccgtc ggacacgagc cccagccgcc ttcggatggg tcacttagct
     7561 tgacccccgt cccgccgatc ccgcagtagc cgttggggtt ctcgtccagg tgcagcggtc
     7621 gggggcaagg ccggctcgta cgggttgagg cgcccagctg ggcgcctgaa acgaagcggc
     7681 gggcgctctg ccaggaccca cctgtgccgc gcgttgagcg accggcgtgg gccgagcgta
     7741 ggaacgcctt cgcttgcccg gtcgacgcgg tctgccgggt gggacgtctg gcgaaagatc
     7801 caggaagtta ctaccatgcg cacgatccgg ccacagctgg gtcggtccgg cgatcttccc
     7861 tggaagggcg agagcacgct ccgctgcaag agcccgttcg catctaggag ggaatggtgt
     7921 cgcagtcccg caggctctcg agtcgcctca ctggctggtt tccatcggcc gcccgttgca
     7981 ctgcgtggct catccggtcg agcccggtcg gctcctcaga gggaagtagt gcacgccgcc
     8041 gcagggggat ccagtgaaag acgtcgggtc ggtgcgtact gccgtattcc gggaggatga
     8101 gtccaatccc ggcgccttcc aggccaacgc gagcatcgtg caggcgggtt tcttcttctg
     8161 ggagatctcc actggcgagg tgagctgcga tccgctcacc ctcgcgctgc acggcatgcc
     8221 cgagaacggc ccgtcggaca tctcgagctt cctggccgca gtacacgagt ccgatctggc
     8281 cgatgtgcgc gatgccttgg ggttgatagc ggaatcctgc ggcaactacc agatcgagta
     8341 ccgcgtcacc tccgacgacg gccaccggtc cctggaagcc cggggccgcg tcctgcccgg
     8401 cgccgacggg ctgccggccc gcatggttgg agtagtcatg gacaccacgg ccgtccatga
     8461 gcgtcacgaa gcggagaggc ggcggctgta cgagcgcgcc acccgtgacc gctggatgca
     8521 ggagctgacc gcggctctgg ccgccgcggt gacggtcaag gacatcatgg ccgccgcaca
     8581 ggcaggactg cgtaccttcg gagcaggcgc gctggcagtg atcgccccgg agggggacca
     8641 gttggccgtc gtcgcctcgt gcgccgacga cgagcagggc gaggactcca tgcgagtcct
     8701 cgacgccacg gtccgcacac tcgtggagga gtcactcgac cgtagggcgc ccgtcctcat
     8761 cggctccgcg gacgcgctga tcaccggata tccgcacctg gcaccgctcg agcagtcggc
     8821 ccgacaggcg tgggcggcac tgccgctcac ggactcgcgc ggccgcgtca gttcctgcct
     8881 cgtcagtttc cccgagccgc aggaattcct gccggaggag cgggccctcc tggtcgccgc
     8941 catgggactg ctcgcccagt cactggagcg agccggcatg tacgagtcgg aacacgcgct
     9001 cgcgaccgag ctccaacgcg gcatgctgcc gcgtgggccg ctcacggtgc cgggtgtgac
     9061 catcgccgcc cgctaccagg ccgccacctc cggcatgtgg atcggtgggg actggtacga
     9121 cgccatcagc ctgcccgacg gcggcgtggc tctggtcatc ggagatgtgc agggacacag
     9181 cgttcacgcc gcgtctctca tggggcggct gcgcaccgcc gtgcacgcct acgcgaacga
     9241 aggacaccca cccgcggccg tcctggaacg caccaaccgc ctgctggccg agctgaacac
     9301 cgacccggac agggccctgt tcgccacgtg ctgctacatc gcgctcaccc cctccgacgg
     9361 aaggctccag gtgtgccggg cgggccatcc ggccccagcg ctgatcacgc cccgcaagcc
     9421 gccgcgcctc ctggaggtcc ccggcggcct ccctctgggg atcgaccggg agcagcggta
     9481 cccgaccacc cgcctgcgca tcgctccggg cagcgtgctc gcgctgacca ccgacggcct
     9541 gctcgaggcc gtgaacaagg acatcgacca gggcttcgag aggtttctcc ggggtctgcg
     9601 gggggctccc acggcggacc tggagaccgt tgtcgatgcc ctgcttgccg gtacgcagaa
     9661 ggctcacggc ctgggcgacg acgtcgctct gctcctggct cgtctgaaca agcccgaccg
     9721 ccgcagctga cccaggcccg acccggaatg tcctcaactg gctgggatcg cagggcactt
     9781 gtatccacga ccaatcgaat ttcccgtctg cggtgctgcc cggcgcaaga cgaagagcgc
     9841 caaagaaacg agacctctgt cgaacgtcat cgaccagcag ggtaatttac atcggtggtt
     9901 gggactgcct ggtcatgctc catgcgggcc ttggcatgcc gcatcggcaa tgtcgctgga
     9961 tgccgcgaat ggcagagaat taccgagagc gagctgacgt atggaaaatt tccgaattcc
    10021 ggacctgtac atacccgtac tggcagcgct caatccagaa ctccaggagg ccgcggcggc
    10081 cgctgaggcg tggttggacg agttcggtct ggtgcccacc gaagaggcac gtcggcatgt
    10141 gcagcgcact cgtgtggacc ggctcaccgc gtggctgtgc ccgaacgcct cacaggaggc
    10201 gctgacgctg atcacccagt ggaacgcgtg gctgttccag ttggacgacc agttcgacga
    10261 tgacccggtg cgcggttacc aacccgagca gtggcgggac gcgttcggtc cgttgttcgc
    10321 cgtattcgac ggaaacgtta cgactgggcg actggcgcgt tctctggccg atctgtggcg
    10381 ccgtaccgtg gctgtccgtt cttccgcatg gcagcgcaga tttgtcccgc acctgttgtg
    10441 gtatttcgac agctaccggg ccgatatgat tcatcgggag gaagggcgtg tacccggcct
    10501 gcagcaatat ctcgcccatc gccgtgcctc attcgcattc gacgccgttc tggacctgat
    10561 ggaaatcggt atcggtgtgg acctgcccga ccaactgcat gcgaatccag ccttcgcgga
    10621 catgcgagag gcagtgatct acgcgaatgc ctgcattaac gatctctact cgctgcccaa
    10681 agaactcgcc catgactacg cgttcaacgc cgtcgcggtg atctgccacc atcaccggtg
    10741 cagcctccag gaggcggcgg agcgagtggc cgtgatgcag gccggatacg tccagcgcat
    10801 cctcgatctc gaacaggtcc tgcccgggcg gctggcacgt tccggcctcg ccgacgacgt
    10861 catcgtcgac gcgctccgct gtgtcaggga cttccatgcg ctcaccgccg ggaacgtcgc
    10921 ctggtcgaag gagaccgggc gctatgcgga ggtagaggcc aagccgacct atctggcgga
    10981 cttgtttatt ccgtaggacc cgtcggccgt cgcccatgca cgtcagggca ccgccgtggc
    11041 agcggcacgg aggaccctca gtcggcacgg tgccgacctg gcccggacgc cggccgacct
    11101 gtcattcctc cgtcggtgcc ggggcgagtc ctgtggggca tgaggccccc cagttcgtct
    11161 cgaacggggt actcagcttg acccccgtcc cgccgatccc gcagtacccc gccggattct
    11221 tgtcgaggta ctgctggtgg tagccctccg ccggatagaa cgggcggctg tcggcgggga
    11281 ggatttcggt ggtgatgtcg gcgtagccgg agttgtggag gacggtgcgg taggcatcgc
    11341 gggaggcttc ggcggcctgt tgctgggcgg gggagtgggt gtagatcgcg gagcggtact
    11401 gggtgccgac gtcgttgccc tggcggaaac cctgggtggg gtcgtgggac tcccagaaga
    11461 gcttcaggag ggacgtgtag gggacgactg ccgggtcgta gacgacgcgg acggcctcgg
    11521 tgtggccggt gtggccgctg cagacctctt cgtaggtggg gtgtggggtg tggccgccct
    11581 gatagccgac gagggtggtc cagacgccct cggcctgcca gaacttccgt tcggcgcccc
    11641 agaagcagcc caggccgaag tcggcggtct ccagaccgtc cgggtacggg ccgagcagcg
    11701 ggttgccgag gacggtgtgc cgggcgggga cggtgaaggc ccgttcgggg cggccttcga
    11761 gcgcttcctc gggggtgggg aggtgggtct tgaagcggga gaacagcatg aggatcaggc
    11821 tcctgaggag ggagagggga cctgaggggg catggggatc aacaccgggg gaggggacgg
    11881 cattccgcgg acggttaccc gccctctttt ccttatccgc cctattttcc cggcggcacc
    11941 cgccctactt tcccggcggc ggaaagcccg ccgaggtgcc gccgagctgt tcccagccgg
    12001 cgatggccag ggcgcggtag gcggcgtact cggcggcggg gctgcggccg taggaccagg
    12061 ggacggcgcc cacatggccg tcgacgagac ggagctgctc catggcttcg gcgtagcgct
    12121 cggcgcgtac caggaaccag acgagcagat ggcggacgtg cggtgccatg gggtggtcgg
    12181 cgggcgcctc gcggagcgcg aagtgggcgc cctcgatggc gcgctcgacg accgcgctct
    12241 ggtagaggct gcggaccatg ttggcctcgg ggaggtgctc gtagaccgcg aagaggggga
    12301 gggcggggag gagggtgccc gcgggggcgg cggccgcggc gcgctcggcg aacgcttcgg
    12361 cctccgtgcg ggagccgtgc cacttctgtg accagtacgg cagcgcggcc agatgcgcgc
    12421 ccatgtgctg cggggcgcgc tgggcgacct tggaccagag ttcctcgtag tcggccgggc
    12481 ggtcgcccag gccgcgggcg acggccagct cggtgatgta cgggatcggg ctgccgggcg
    12541 ccagcagcgc cgcctcccgg cagaccgtac gggcctcctc aaggatcatg cggaagtcct
    12601 gcgagcccgg atcgcgcaac gcctggacga ccaggaactg ggcgtgtgtc tgggcgccgc
    12661 cggggtcctt gggggcctcg gagcgccagg tgcgcagcca gatgccgccg gtccggcccc
    12721 cgccgccctg ttccgtgccg ccctcggcca gctcgaacgc ggccgcgccg gccagcgtct
    12781 gcacccgctg ccagcggcgc tcccagtcgt cgccggtgga cttcagcagc tcggccgccg
    12841 ggcgccagtc gtgcgtccgc cgcatctcgg ccagcgcctc gtccagctcc tggtcggggc
    12901 ccggcagccg tacgtcgagc tgctccagcg ggacgaagcc gtagccggcc atcgggtcgg
    12961 tggccaccac cagaccctgc cgggtgtgct gtacggcccg ccggcgccgc atccagggca
    13021 ggaagacgaa gccgccgagc gtgagcgcgg cgaggagaac cagcagagca tccatgtggg
    13081 gtgtcctgta cctgtaacgg tgcggcgtgc gggcgtacgc ggagcggtcg ggcgggtgga
    13141 gcggggccgc agcaccgcgg tgggaaccgg tgtgcggtcc ttcgtatgta tccactatcc
    13201 agcgaaccag aaagttccgg aaagttcggc cctgccacag gcggcgccct cgggcgcggg
    13261 gccgactacc ctcagcaggc atgagcgatc aacgcgacca gcgcccccag cattttgaaa
    13321 cccgtgccat ccacgcaggt caggagcccg accaggccac tggcgcggtg gtgccgccca
    13381 tctatcaggt gtccacttac aagcaggacg gcgtgggcgg gctgcgcggc ggctatgagt
    13441 acagccgcag cgccaacccg acccgtaccg ccctggaaga gaacctcgcc gccctcgacg
    13501 gcggccgccg cggcctcgcc ttcgcctccg gcctcgctgc cgaggactgc ctgctgcgga
    13561 ccctgctgac ccccggcgac catgtcgtca tccccaatga cgcctacggc gggacgttcc
    13621 ggctgttcgc gaaggtcgtc gagcggtggg gcgtggagtg gtcggtggcc gacacctccg
    13681 acccgcaggc cgtacgcgag gcgctgcggc cccgtacgaa ggtgatctgg gtggagacgc
    13741 ccagcaaccc gctgctcggc atcagcgaca tcgcggcgct ggccggcatc gcccgcgagg
    13801 cgggcgccag gctcgtcgtc gacaacacct tcgccagccc ctaccttcag cagccgctcg
    13861 ccctcggcgc cgacgtggtg gtctactcca cgacgaagta catgggcggt cattcggacg
    13921 tggtcggcgg cgccctggtc gtcaacgacg acaccctcgg cgaggaactc gcctaccacc
    13981 agaacgcgat gggcgcgatc gccggaccgt tcgacgcctg gctggtgatg cgcggcatca
    14041 agacgctggc cgtccgtatg gaccggcaca gcgccaacgc ggcacgcatc gcggagctgc
    14101 tggtctccca caagaaggtg acccgcgtct actacccggg gctgtccgag caccccggcc
    14161 acgagatcgc ggccaagcag atgcggtcct tcggcggcat ggtgtcgttc caggtcgcgg
    14221 gcggcgagca ggcggcggtg gaggtctgca accgggccgg gctgttcacc ctcggggagt
    14281 cgctgggcgg cgtcgagtcg ctgatcgagc acccggggcg gatgacgcac gcctcgacgg
    14341 ccggttccgc gctggaggtc cccaacgacc tcgtacgcct ctcggtcggc atcgagtccg
    14401 tcgacgatct gctggccgat ctgacccagg cactgggctg acggtccggt cgtcgccggc
    14461 gttcaccacc cctccaccgg aggggtggtg cggaccggtg gcggcgtcca gggctgggcg
    14521 acgaccgccc aggccagagc cgtcagcgcg aggagcgcga gcagccagcc gatgcggcgc
    14581 agcacccggc ggtgcgcctt acgacggcgg ccgcgggcgg cggcccggac ggccagatcg
    14641 ggcggtacga gcggatgcgg cccggccagc atccgccgta cctcggtctc cttgcggtcg
    14701 ggcaggctca tggggccgcc ggtttcggtt cgggccggcg gctgcgcatc tccgcgaggg
    14761 cgcgcaggca cagcgcgtgt acccgctcgg tgggcaggcc gagttgggcg gcggtctgct
    14821 cctcggccac gccttcgtag agacgtagga cgagcaccag ccgctcctgt ggggacagcc
    14881 ggtccaggag cccgccgcgt ggccggcggt gccgccacgc ggtgtgcgcg aagtgggcgg
    14941 ccatctcctg gcgggtgcgc tcgtagggat cctcgccgcg cagccggtcc cagacggcgt
    15001 aggtccgcga cagcgcgcag gtcagcaact cctcggcggc cggggcgggt cgggataccg
    15061 gctcaccggt gagcagggcg gcggtatgca gcagacggcc cgccgcgccc gccacgaaca
    15121 cttcgaactc ccgggcgtgg cggcgctcct gcgccagtcg ccgctctcgc accgcgcctc
    15181 ccggatgacg gacacccgac ccttggcgct cctatagcac ggcagtgcgg ccaccgggtc
    15241 aagaggcgcg gcggacgtgg cggacgcggc ggacggcggg caggcggccg cccggcgcgg
    15301 tccgggcgcg ggacccgccg acgtcaggac gtcggaaccg ccgacgtcag gacgtcgggc
    15361 ccgccggcgt caaggacgcg gtgatgtcgg cgagggaggc gttgaaccgc gtcaggagcg
    15421 tggtgaacgc ctcgcgttcc tcctcggacc actcgtcggt caccagggcc atcagcgcac
    15481 ggcgcgaggc ccgcacctcg tccagacggg cgtggccgcg ctcggacagc tggagcacca
    15541 cggcccggcc gtcctcgggg tgggtggcgc ggctgaccag cccggagtcg accagcgggg
    15601 cgacctgccg ggtgaccgtc gaggagtcga tgcccatgcc ggcggccagg gccttgacgc
    15661 ccatcggacc ttcctggtcc aggcggttga gcagcaggta ggcggcgcgg tccatggagt
    15721 tgcgcgcctg cccgacgccg ccgagccggc tctgttctgc gcggcgggcg aagacggcca
    15781 cttggtgctg cagcgcgtcg aggagagcgg ggtcggtgtg ggtcgtcatg tccgaagagg
    15841 tgggcatggc cgggagctcg cttcatgggg tgtgtacgga ttggaggaca gagtacgcgg
    15901 acccggcgcg gagcgtacct gcgctgtcca ttccgataac gccccgtaac ccccgggcgg
    15961 ccgtagggga cgcgcggtcc ggcagctgcc cgccgcgggc gtgacacgcc ctgcgaccag
    16021 gaaggtccgc ccgtcggaca aaaaggcccg ccggtcggca aactgcgaga ctggcggcat
    16081 ggccgatcac acgccgcgta cgccgcacga gacccccgcc gcaccccccg ccgatggtcc
    16141 ggtcaccgcg ggcgcgcatg ccatgatcac ggtcgatgag gtacgcgagg cgcacaagat
    16201 gctctccggt gtctcccggg ccaccgcgat ggagggcagc cgctatctgt ccgggctggt
    16261 cggctccccc gtacatctca agtgcgagaa cctccagcgc accggctcct tcaagatccg
    16321 tggcgcctat gtacggatag ccgggctctc ggcgcaggag cgggcggccg gtgtggtggc
    16381 cgcgagcgcg ggcaaccacg cgcagggcgt ggcgctcgcc gcgtccctgc tcggtgtccg
    16441 gtcgacggtg ttcatgccgg tcggcgcccc gttgccgaag gtcgccgcga cccgcgacta
    16501 cggcgcggag gtgcggctgc acggccaggt ggtggacgag acgctggccg ccgcccagga
    16561 gtacgcacgc gagaccggtg cggtcttcat tcaccccttc gaccaccgcg acatcatcgc
    16621 cggccagggc acggtcggcc tggagatcct ggagcagtgc ccggaggtgc gcaccatcgt
    16681 cgtcgggatc ggcggcggcg ggctcgcgtc gggcatcgcg ctagcggtca aggcgctgcg
    16741 gccggatgtg aaggtcatcg gggtgcaggc ggcgggcgcg gcctgctatc cgccgtcgct
    16801 ggcggccggg cgtccgctgg cgatcgaggg gctgtcgacg atggcggacg gcatcaaggt
    16861 ggggcggccc ggcgatgtga cgttcgggat cgtcgaggaa ctggtggacg aggtccgtac
    16921 ggtgaccgag gaccagctct ccagcgcgct gctgctgtgc ctggagcggg ccaagctggt
    16981 ggtcgagccg gccggggcca gcccggtggc ggcgctgctg gccgacccgg gtcactttga
    17041 ggggccggtg gtcgcggtgc tgtccggcgg aaacgtcgac ccgttgctga tgcagcgcat
    17101 cctgcggcac ggtatggccg ccggcggccg ctatctgtcg ctgcggctgc ggctgacgga
    17161 ccggccgggg gcgctggcga tgctgctcgg tgtgctgtcg gtggtcgatg cgaacgtcgt
    17221 cgatgtcggc catgtgcgta cggatccgca gctcggtctg accgaggtcg aggtggagct
    17281 gcatctggag accaaggggc cggagcactg cgacgaggtg cgcgcggcgc tcggcgaggc
    17341 ggggtacgtc gtcgcggaat gagtggacga cgccgataag cgaactacgc cgatagagga
    17401 tgggacgtgc ggcgccgcgg gtataccgtg gcgccgcacg catgttggcg aacaggtgtt
    17461 cccgttctgt tcgtgcggtg gaaatcgaaa ttcgatcgcg atgtatcgcg ttcgtgagta
    17521 gcatcgcggc tgcgagggcg ccgggtgagt catggcctcc cgctgcggac aaatgcccac
    17581 agggcaggcg aagtccgcga aacgtaatat tcgacctgga actgacccaa gccatgggag
    17641 tacccatatg ccaggcgcca tttacgccga aggtctggtg aagaccttcg gtgacgtgag
    17701 ggcactggac ggcgtcgatc tcgacgttcc cgaaggaaca gtcctcggaa tgctcggccc
    17761 caacggtgcc ggcaagacca ccgccgtacg ggtcctgacg accctgctcc agcccgaccg
    17821 gggcaaggcg gtggtcgccg ggatcgatgt cctcgcgcac cctgaccaag tgcgccggtc
    17881 catcggcctc tccggccaat tcgccgccgt agacgagtac ttgaccggcc gcgagaatct
    17941 ggtgatggtc gggcagctct accagatgag cggtcgcgac gccaagcgcc gggccgctga
    18001 gctgctggaa cgcttcaatc tcggcgacgc cgccgaccgc accgccaaga cgtactccgg
    18061 cggtatgcgc cgccggctcg acctcgcggc cgcgctggtc gtcagcccgc ccgtgatgtt
    18121 catggacgag ccgaccaccg gcctggaccc gcgcaaccgc caggcgctgt gggacgtcat
    18181 ccaggaactg gtcgccggcg gtacgaccct gctgctcacc acgcagtatc tggaggaggc
    18241 cgaccgcctg gcgcacgaca tctgcgtcgt cgaccacggc aaggtcatcg cccgcggtac
    18301 gtccgaccag ctcaaggcgc gcaccggcgg tgagcgcgtc gaggtcgtgg tgcacgcccc
    18361 cgagcacctc tccatcgccg acgaggtcct gcgcggcttc ggcaagggcg agggcacgat
    18421 cgaaccgcac atccgcaagc tcacgatccc ggtgaccggc ggcgccaagc tgctcgccga
    18481 ggtcatccgc gaactggaca cccggggcgt ggagatcgac gacatcgggc tgcgccgccc
    18541 caccctcgac gatgtgttca tctcgctgac cgggcacgcc gccgaggccg acgagaacgg
    18601 cgcgaacggc aagaacggtg gcaagggcgg cgggggcgcc gtcgggcggc agaagaaggg
    18661 caggaagggc gccgagccgg gcgagccggt cgcgccgagc ggtgcggccg ccgcggccga
    18721 agccgtggac gccggcgtga cgacgaacaa ggagggcgtg aagtgaccac ggtgacccga
    18781 acggccggtg gtgacgcccg catccggacc ccacagtccc gcggcggcct cggccggtcc
    18841 atacgcgact cactcgtcgt cgccaagcgc aatctgatcc ggatgatccg gatccccgag
    18901 gtagtgatct tcgggctgat ccagccgatc atgttcgtgg tgctgttcac ctacgtcttc
    18961 ggcggctcca tcaacatccc cggcgccccg gcgggcgacg ccgaggccta tcacgagttc
    19021 ctgatggccg ggatcttcgc gcagaccgtc accttcgcca cggcgggcgc cggcgcgggc
    19081 atcgccgacg atatgcacaa ggggctcatc gaccggttca ggtcgctgcc gatgtcccgc
    19141 ggcgcggtgc tcaccggccg aaccctcgcc gacctcgtac agaccgcgct gacgctggtg
    19201 gtgctggcgg tcgtcgcgct gctgatcggc tggcgcaccc acgagaacat cgccggggtg
    19261 ctggccggct tcgcgctgct gctcctgctc ggctacgcct tctcctggat cggcgcgctc
    19321 atcggcctct cggtgcgtac gcccgaggcg gccacgtccg gcgggctgat ctggctcttc
    19381 ccgctgacct tcatctcgaa cgccttcgtc ccggtcaacg gcatgccggc gttcctgcag
    19441 catgtcgcgg agtggaaccc gttcagcgcg acggtggccg cggcccggga gctgttcggc
    19501 aactccatcg accgggtgcc gaagtcggtg accggcgcct ggccgatgga gcacccggtg
    19561 ctggcctcgg tgatctggtc cgtcctgatc atcgcgttct tccggacgct ggcggtccgc
    19621 aaataccggt cggccacggc ctgaggggcg tacggcgtgg agcacgccga cggcgtacga
    19681 cgcagcgaag cggcccggag cctcacgctc cgggccgctt cgtcgtctgc gggcgtctcg
    19741 ggcctcagcc cgtgtacggc ttggcgtcga gaatcttcac ggacgccttc ttgccgttgg
    19801 ggagctcgta ctccgcggcg gcgccgacct tcttgccgtt cacgccggtg cccagcggcg
    19861 actgcgggga gtaggtctcg atgtccgagc tcgcgtactc ccgcgaggcc agaaggaacg
    19921 acagcgtgtc gtccgggtcc ccgtcgaacg cgatggtgac gaccatgccg ggagcgacga
    19981 cgccggtggc ggcgggggct tcgccgacct tcgcgctctg cagcagctgg gtgagctggc
    20041 ggacgcgaag ctcctgcttg ccctgctctt ccttggccgc gtggtacccg gcgttctcct
    20101 tcaggtcacc ttcctcgcgg gccgccgcga tcttctcggt gatctcggcg cgtgcgggac
    20161 cagacaggtg ctccagctcg gccttgagct ggtcatacgc ctcctgggta agccaggtga
    20221 cgttctcgct ggtctgggtc acaggtgctc ctcgtcggta ctggggataa atcaaacgcc
    20281 ctaccaggaa ggtttgcgcc ttcacaggtg ggcgaaacca cgagcctaac aattccggca
    20341 caaaacgggg aagaggaaat tcacagtgac cgcacaggaa cgcatcatcg ctgatcagag
    20401 gcggtcacga cacgccctgc cgatgagcgg gtgggcgcgg tcaggtcgct tcggttgact
    20461 ttggccgggg ggtccggtcg gtcagcggct gccggacacc gtacagccga ccagcaccgc
    20521 gttggtcgcc cgctttgtcg tacgcactgt gacctcggtg tccacctggt ccgcgcgccg
    20581 gtcgatggtg acgtccttgc ggccgacctc ggagccgtcg gcggactgtg agcggagcgt
    20641 gcacacaccc ttgtcgtccg tgcccttgac gacctcgaga tggaccttga ccgcgtggtc
    20701 ggacaccgcg tcccaggtga tcacccggcc gctgagatcc tgccctgtga tgtacgagac
    20761 gcccgcccag ccgatcacgc ccagcagcgc gacgccgagc accgagccga cgatcttgag
    20821 cttgcggtcc gcgcgctggt cggcggagcg gccgtagcgt ccgtccggga gcccttcgcg
    20881 caccgcggtc atgatcagtc ctcctggtac ggggacctgg accatgaacc cccggggggt
    20941 ccccgcccca gggaatacag cgcccccttg cttcggtcac tataggaggc atcttc
//
