LOCUS       NZ_CP084681            22238 bp    DNA     linear   CON 30-APR-2024
DEFINITION  Streptomyces inhibens strain NRRL30439 chromosome, complete genome.
ACCESSION   NZ_CP084681
VERSION     NZ_CP084681.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces inhibens
  ORGANISM  Streptomyces inhibens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9696490)
  AUTHORS   Barry,C.P., Gillane,R., Talbo,G.H., Plan,M., Palfreyman,R.,
            Haber-Stuk,A.K., Power,J., Nielsen,L.K. and Marcellin,E.
  TITLE     Multi-omic characterisation of Streptomyces hygroscopicus NRRL
            30439: detailed assessment of its secondary metabolic potential
  JOURNAL   Mol Omics 18 (3), 226-236 (2022)
   PUBMED   34989730
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9696490)
  AUTHORS   Barry,C.P., Palfreyman,R. and Marcellin,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2021) EMS, Australian Institute for Bioengineering
            and Nanotechnology, Cnr College Rd & Cooper Rd, Brisbane, Queensland
            4103, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. APRIL-2018
            Assembly Name                     :: AIBN_shyg
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 239.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022221585.1-RS_2024_04_30
            Annotation Date                   :: 04/30/2024 04:58:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,775
            CDSs (total)                      :: 8,682
            Genes (coding)                    :: 8,305
            CDSs (with protein)               :: 8,305
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 377
            CDSs (without protein)            :: 377
            Pseudo Genes (ambiguous residues) :: 0 of 377
            Pseudo Genes (frameshifted)       :: 158 of 377
            Pseudo Genes (incomplete)         :: 310 of 377
            Pseudo Genes (internal stop)      :: 38 of 377
            Pseudo Genes (multiple problems)  :: 116 of 377
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:32:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5345773
            Orig. end                         :: 5368011
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084681.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Australian Institute for
            Bioengineering and Nanotechnology, Building 75,Cnr College Rd &
            Cooper Rd, Brisbane City QLD 4072.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22238
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="18"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22238
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22238
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12238](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12238
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(949..964)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.73"
                     /tool="antismash"
     gene            complement(1880..2293)
                     /locus_tag="KI385_RS24455"
                     /old_locus_tag="KI385_24520"
     CDS             complement(1880..2293)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014176901.1"
                     /locus_tag="KI385_RS24455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24520"
                     /product="hypothetical protein"
                     /protein_id="WP_238574270.1"
                     /transl_table=11
                     /translation="MSDINSLVGEIVPAVGAAVGAYGVNVLSRAEDQAADATVRLGQRL
                     LDRILRRTPDRAPIEAAVTTLATTDGDPDALAALRLQIRGALAADPSLVTELAALLPER
                     SAAQADGARAVAVTGNVPGIVSTGDAAINIQRR"
     gene            complement(2542..3777)
                     /gene="rocD"
                     /locus_tag="KI385_RS24460"
                     /old_locus_tag="KI385_24525"
     CDS             complement(2542..3777)
                     /EC_number="2.6.1.13"
                     /GO_function="GO:0004587 - ornithine aminotransferase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (37-358). E-value: 2.2e-102.
                     Score: 334.5. Matches aSDomain:
                     nrpspksdomains_KI385_RS24460_Aminotran_3.1"
                     /codon_start=1
                     /gene="rocD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089890.1"
                     /locus_tag="KI385_RS24460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24525"
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="WP_238574271.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.7e-114, bitscore:
                     381.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPTRTAAVHAPRSSAELIQAEGPVLAHNYHPLPVVVARAEGVW
                     VEDVEGRRYLDMLAGYSALNFGHRHPALIEAAHRQLDQLTLTSRAFHNDRLAGFAEGLA
                     ELTGLDMVLPMNTGAEAVESGIKVARKWAYDVKGVPADRATIVVAADNFHGRTTTIIGF
                     SNDETARAGFGPFAPGFRVVPYNDLAALEAAVDETTAAVLIEPIQGEAGVVIPDAGYLT
                     GVRELTRRAGCLFIADEIQSGLGRTGTTLAVDHESVVPDVLLLGKALGGGIVPVSAVVA
                     RREVLGVLGPGQHGSTFGGNPLAAAVGSAVIELLATGEFQRRAAELGDQLRTGLAALTG
                     KGVTGFRARGLWAGVDIDPALGTGREISERLLKEGILVKDTHGSTIRLAPPLTITGEEL
                     ASALGSLERALG"
     aSDomain        complement(2704..3666)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_KI385_RS24460_Aminotran_3.1"
                     /evalue="2.20E-102"
                     /label="KI385_RS24460_Aminotran_3.1"
                     /locus_tag="KI385_RS24460"
                     /protein_end="358"
                     /protein_start="37"
                     /score="334.5"
                     /tool="antismash"
                     /translation="VARAEGVWVEDVEGRRYLDMLAGYSALNFGHRHPALIEAAHRQLD
                     QLTLTSRAFHNDRLAGFAEGLAELTGLDMVLPMNTGAEAVESGIKVARKWAYDVKGVPA
                     DRATIVVAADNFHGRTTTIIGFSNDETARAGFGPFAPGFRVVPYNDLAALEAAVDETTA
                     AVLIEPIQGEAGVVIPDAGYLTGVRELTRRAGCLFIADEIQSGLGRTGTTLAVDHESVV
                     PDVLLLGKALGGGIVPVSAVVARREVLGVLGPGQHGSTFGGNPLAAAVGSAVIELLATG
                     EFQRRAAELGDQLRTGLAALTGKGVTGFRARGLWAGVDID"
     gene            complement(3774..4604)
                     /gene="ddaH"
                     /locus_tag="KI385_RS24465"
                     /old_locus_tag="KI385_24530"
     CDS             complement(3774..4604)
                     /EC_number="3.5.3.18"
                     /GO_function="GO:0016403 - dimethylargininase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ddaH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988508.1"
                     /locus_tag="KI385_RS24465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24530"
                     /product="dimethylargininase"
                     /protein_id="WP_238574272.1"
                     /transl_table=11
                     /translation="MPTSRESRPRRYLVCEPRHFEVRYAINPWMRAEAPVDTALAGRQW
                     ETLMRAYRVHGHTVEHVAPVAGLPDMVFAANSALVVGGRVFGSSFHAPQRRPESTEYET
                     WFKTAGYDVYRPESLCEGEGDLVPAGRYILAGTGFRTTRAAHDEVQEFFGVPTIGLQLV
                     DPYFYHLDTALFVLEEDAETGAANIAYYPEAFSSGSREVLRRLFPQAVIATRDDAMAFG
                     LNSVSDGRQVFIAPQATGLIDQLTARGYVPVPVDLSEFRKAGGGIKCCTQEIRS"
     gene            complement(4773..5261)
                     /locus_tag="KI385_RS24470"
                     /old_locus_tag="KI385_24535"
     CDS             complement(4773..5261)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712426.1"
                     /locus_tag="KI385_RS24470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24535"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_128505005.1"
                     /transl_table=11
                     /translation="MTNKAAPFDDLDRKIVAALIDNGRASFAEIGAAVGLSSTAVKRRV
                     DRMRENNVITGFTATVRPAALGWLTEAYVEVYCDSAAPPRRLAEVVRNHPEIAAAMTVT
                     GGADALLHVRATDVEHFEEVLERIRAEPFIRKTISYMVLSHLLPESPEAGARQSSAPE"
     gene            5468..6262
                     /locus_tag="KI385_RS24475"
                     /old_locus_tag="KI385_24540"
     CDS             5468..6262
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471098.1"
                     /locus_tag="KI385_RS24475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24540"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_238574273.1"
                     /transl_table=11
                     /translation="MRDPRESGGGSGAAPTRADRARRVAHVLRGQVLRGAFPDGVLPDE
                     RALVAEFDTSRNTVREALGLLRDEGLVARRQGVGTVVVGRAYQHPLGELSGLAEVLQRH
                     GVVVNEVREARSVRPPRTVARRLGLAEGGPAVYLERLRRVDGTPLSLDCTYLIPEVGEP
                     LLARGRDTLERHDVFDLIETAAGTPLGTAEVSVQAVVADPATCAVLAMPAGGAVLAVER
                     LTRLADGRPADLEFIHLRGDRLTLHATLDRARGGPGAAHRQP"
     gene            complement(6308..7627)
                     /locus_tag="KI385_RS24480"
                     /old_locus_tag="KI385_24545"
     CDS             complement(6308..7627)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016578882.1"
                     /locus_tag="KI385_RS24480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24545"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_238577829.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.7e-40, bitscore:
                     136.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPAHFHGTRQLLVPELLLLPDGPVRGQAVLVDGGKFRTIGPAEQ
                     LIAAHRDLQPVRLDGHLLMPGFVDAHHHLTQSFGKAQSFGQPSEIFKTVWEPLEHALDE
                     ESAYLSAKLAALEALRGGFTTVADAGTRAPVDVGAVAKGTEEAGVRCVLSEIVSTGTGG
                     PAHLARWEGHPLIHPSLAIAVPEDAPGEVIKKTADMCAEAGAVLQIHVNEHLASVERSL
                     KSVGRRPLEHLHHIGALGPHTLGAHATLLTPSEMRLLADSGAAISYNPVASAWKGNGVA
                     HATMLAAMGVRFGMGTDGTRGDGFRLVDAGETAQRLAYGMASGDSVCGAGRTWLTHATA
                     GSADALGLGKVTGEIAAGKAADFLVVNLAVPELTPSYDLRWELVRLANRDQIAAVVVNG
                     TLRLWHGWPPDWDGHALVARAAKLGPEVVRRAKLQRVEPV"
     misc_feature    complement(7866..7880)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.85"
                     /tool="antismash"
     misc_feature    7867..7880
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.78"
                     /tool="antismash"
     misc_feature    7867..7881
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.54"
                     /tool="antismash"
     misc_feature    complement(7981..7998)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     misc_feature    complement(8015..8034)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 24.07"
                     /tool="antismash"
     gene            8114..9016
                     /locus_tag="KI385_RS24485"
                     /old_locus_tag="KI385_24550"
     CDS             8114..9016
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359762.1"
                     /locus_tag="KI385_RS24485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24550"
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_238574274.1"
                     /sec_met_domain="RimK (E-value: 5.6e-09, bitscore: 34.8,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 1.4e-05, bitscore:
                     24.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLCFLVEEQYRYDGMPLDVIRQLGAWGHQVDVLWPGRSLIPISE
                     AIQAGSHDAWVLKTVSGGPGLSLLEAAACVGLTTVNDVRAIRGVRDKALAAVIARSSGL
                     PVPVTYAAARAEEFAQIPEAQYPLVVKPADGSSGRAVRLVASPEQLLDQALSAEPGEGG
                     GAAGGLLIAQPYVPNSGTDLKVYCVAGELYATERCSPLHPGRAVRERQVPLTPEVARIA
                     AEIGAVFGLDLYGVDVLLGPDGPVVVDINDFPSFRQVPDAVARVSAAVLHLARKGPRQP
                     VVDLASPATVPLAAIGGDR"
     gene            9013..9843
                     /locus_tag="KI385_RS24490"
                     /old_locus_tag="KI385_24555"
     CDS             9013..9843
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173589.1"
                     /locus_tag="KI385_RS24490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24555"
                     /product="alpha-L-glutamate ligase"
                     /protein_id="WP_238574275.1"
                     /sec_met_domain="RimK (E-value: 7.3e-06, bitscore: 24.7,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVGLITADPAHPVLAAVTGLLTPHHRVEHLDPGGDVQDLDRGDL
                     ADVYLLKARTPRALALAARLEGYGAPVINSAAATARCQDRVEMAALARAAGLPFAQTAL
                     VDGLGQLATAGEPATPLVIKSRYSRRHDLVTRADSAARLRELAAAWPDEPVVVQEFTAN
                     SGWDHKLWVVAGQLFTGLRRSELAPDGRGPTLPLPVDELPAGWSGAALRVGEVFGLEVY
                     GVDILDAGGGAPLIVDINAFPGIRGQAGAPEALADLALRTAAQAERTASQASLK"
     gene            10001..12238
                     /locus_tag="KI385_RS24495"
                     /old_locus_tag="KI385_24560"
     CDS             10001..12238
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382258.1"
                     /locus_tag="KI385_RS24495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24560"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_238574276.1"
                     /sec_met_domain="T1TS (E-value: 9.4e-82, bitscore: 274.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPNFYTPYPARLNPHLETARTHSKKWARDMEMLEGSGIW
                     EEKDLDAHDYALLCSYTHPDCDADALSLVTDWYVWVFFFDDHFLEKFKRTLDREGGKEY
                     LDRLPAFMPMDLTTPVPEPTNPVEAGLADLWARTVPHMSLDWRRRFAESTEHLLNESLW
                     ELSNINIHRVPNPVEYIEMRRKVGGAPWSAGLVEYATGAEVPAAVAGSRALRVLRDTFS
                     DGVHLRNDLFSYQRETEDEGELSNGVLVLETFLNCTTQEAADAVNDLITSRLQQFENTV
                     VAELPPLFVEKGLDPKSCAEVLAYAKGLQDWQSGGHEWHMRSSRYMNGGGSAAGTSLPW
                     SPFSVGGPGTSAADLRTALATAGALRFRSSTHVPHQKVGASQIPDIHMPFTTTLSPHLE
                     GARRRVIAWAHRMGILRPQPGVPLSDVWDEPAMARHDLALCAAGIHPDATPEQLDLSSA
                     WLAWGTYADDYYPQVFGRTRDIAAAKVCTERLSAFMPLEPSAGTPEPVNALERGLADLW
                     TRTAGPMTLEARRMFRETIDKMTASWLWEIDNQIQNRVPDPVDYIEMRRATFGSDLTMS
                     LSRIGHGRQVPPEIYRTGPLRSLENAAADFACLMNDVFSYQKEIEYEGEVHNGILVVQT
                     FFGCDYPTALNIINDLMTSRMHEFQHVAAHELPVVHDDFDLSPEARKALDGYVHELENW
                     MAGILIWHRGCLRYIEPELRHPPGSPGWLGAPTGLGTSAARIFQRAVAGVG"
     gene            12447..14555
                     /locus_tag="KI385_RS24500"
                     /old_locus_tag="KI385_24565"
     CDS             12447..14555
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981083.1"
                     /locus_tag="KI385_RS24500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24565"
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="WP_238574277.1"
                     /transl_table=11
                     /translation="MAAGSPTGRSAGSSASRRAQEARRQERLLREQWQAARRQAERWEA
                     ASEGERRVAAQLLMLTERGWRLLVDRRWPGTRAANVDMLLIGPGGVFVIDVKNWRAAPE
                     ASAGRLRAGGFSRDEHRRKLLAVTKTAESAVASLGMSPVAVRPLMAFAGQRVDTELGRV
                     RLLGEHEIGPALLSERTRLSVQSVRALAEHLARAFPEYEAPPAARPAVVGARPPDAASD
                     GLFDLDGLREAALDEARRAPIEQWMTFLDPDQLTLVRRNWAGPARISGPAGTGKTVVAL
                     HRAAYLAQRTNGRILYVTFANNLPRVQATFLKTMAPAVADRIEFRSLHSWAQEYVSGRG
                     VPVRLHRKKAETAFSLAWKHVGRDSCLAEIDPLPHYWQEEINYVIKGRGIASFEEYAAL
                     VRRRRRAGLRRPHRQAVWALYEAYESERVERAVHDFNDVLSLALAEAAGRTGHGAYTAV
                     VVDEVQDLTLVGVRLLHALVGDSPNGLLLVGDGQQAVYPGGFRLSDAGIDIRGDRGQVL
                     RANYRNSKEIVDTALSVVAEDSFEDLDGLPTPGRRDVDLTYHDGRVHRAVLPTPAAHDE
                     ALLAALRALTPQQLADSAVLCPTQRAIERYQRLLTRAGIPVCPLDRYDGHPVAAVKLGS
                     YRRAKGLEFKRVYLPRYDAGRPADAQHGTASETARERGELARSQLFVAMTRARDMLWLG
                     SVRPQRER"
     misc_feature    12531..12533
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14707..15420
                     /locus_tag="KI385_RS24505"
                     /old_locus_tag="KI385_24570"
     CDS             14707..15420
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089897.1"
                     /locus_tag="KI385_RS24505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24570"
                     /product="MSCRAMM family adhesin SdrC"
                     /protein_id="WP_238574278.1"
                     /transl_table=11
                     /translation="MRRKTAFLGAAALTTVFAVLCPLGAHAATGVITFHTRPGNRPHEI
                     LDPGDDHCYGLGDAYGEVDNDTGVDLVLWTSRDCTGNALATVPAGTAATMGRYGSLQLA
                     EVEPSDESDSQEPSDYRDPSDSQGPSDSRDPSDAPDESYAPDPSDSGDPSDSRDPSNSQ
                     DPSDSQDPSDYQDPSDSPADAESPARSNSPAAPDRPAVSSSPATSSSPARFRKPTRPGA
                     RAHVLTPSASDSPAG"
     gene            complement(15585..16457)
                     /locus_tag="KI385_RS24510"
                     /old_locus_tag="KI385_24575"
     CDS             complement(15585..16457)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446400.1"
                     /locus_tag="KI385_RS24510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24575"
                     /product="NAD(P)H-binding protein"
                     /protein_id="WP_238574279.1"
                     /transl_table=11
                     /translation="MGDVVMSEVVMSDREPILVTGATGNTGSRLVPRLTALGIPVRAAG
                     RHPTQQAGARPVRFDWHDPATHHRALDGAARLYLVPPVAAPDPAAVMLPFLERARTAGV
                     RRVVLLSSSALPAGGPGVGQVHAALPDLFDEWVVLRPSWFMQNFTGSHPHAQGVRTDGT
                     ILTATGTGRVAFVDADDIAAVAVHALIDEPAPPGPDLVITGPQALSYDDIAATLTAVTG
                     RPVRHRPLTYEQQRDRLAAEMPEEFAALLAGLDRAIAEGAEDRVTDTVERITGQPPRSF
                     RAFADQQAW"
     gene            complement(16439..16894)
                     /locus_tag="KI385_RS24515"
                     /old_locus_tag="KI385_24580"
     CDS             complement(16439..16894)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579069.1"
                     /locus_tag="KI385_RS24515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24580"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_238574280.1"
                     /transl_table=11
                     /translation="MSTGNTAPTAPPTPTDLYRHGLRLLLDKDIDGWVALCDDHAVFEF
                     PFAPDGFPKRLDGRPAVAAYMRDYPTHIDLQDFPHLEIHRTDAPDTIVVEMRATGRIVA
                     TGAPYEMAYIAVVTVRNGRITHYRDYWNPLAVPASMAEVKSSWATSS"
     gene            17000..17644
                     /locus_tag="KI385_RS24520"
                     /old_locus_tag="KI385_24585"
     CDS             17000..17644
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089901.1"
                     /locus_tag="KI385_RS24520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24585"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_238574281.1"
                     /transl_table=11
                     /translation="MAERKARADALRNRETVLAAADELFARSESPRSVSMDEIAAAAGV
                     GKGTLFRRFGDRTGLIRAVFEARIEPLRHAVEAGPAPLGPSAPPRERVPALLDAVLCFK
                     LDNRHLSLALEEAGSGSPYQAAHYAWWHGILRDLLERMRDATDGAAGGPADGTGDGTAA
                     GPAPESDFTAHALLAATRADLVEHLVGQEGMDRERIRARLAAFVGTVLGQG"
     gene            <17647..17889
                     /locus_tag="KI385_RS24525"
                     /old_locus_tag="KI385_24590"
                     /pseudo=""
     CDS             <17647..17889
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018089904.1"
                     /locus_tag="KI385_RS24525"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24590"
                     /product="zinc finger domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="ITGHRDDVGAVCPRCGEALRRTRLAGRGAVWCPRCRPEQPHWPTC
                     VRPPLPLPPRRPLPPLPPCTTPGNPPPPRAGWPPR"
     gene            complement(17783..18430)
                     /locus_tag="KI385_RS24530"
                     /old_locus_tag="KI385_24595"
     CDS             complement(17783..18430)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015658536.1"
                     /locus_tag="KI385_RS24530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24595"
                     /product="hypothetical protein"
                     /protein_id="WP_238574282.1"
                     /transl_table=11
                     /translation="MTFQDHMRRMGARALEAFPEALRPQIYVVSFRIWRNDSFDDRHPY
                     LAIGYNTEDELRRVPAEQRDPDPDEARWNYAWWPLDEIAGVIGHDPADPTGAALHTAEV
                     KELGLWYEDDGGDEGEADDDDDDEVSVRNELLELHFDEACIDLARHLHSSGRITEILGR
                     PVPIVLFDMYRAGYEETLTEAANPPEVVADYLAWCREEEAGEAGEAEAGEAA"
     misc_feature    complement(18420..18434)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.98"
                     /tool="antismash"
     gene            complement(18442..20064)
                     /locus_tag="KI385_RS24535"
                     /old_locus_tag="KI385_24600"
     CDS             complement(18442..20064)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI385_RS24535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KI385_24600"
                     /product="hypothetical protein"
                     /protein_id="WP_238574283.1"
                     /transl_table=11
                     /translation="MKNDAHPGPPSGTPQQRIEQWVASVSQRLERLRKIHLPTGFPFDL
                     APDSLEPLEVFLLGRFREKSVPDASGIALDACAYVGEIILDTIGGEWAWARTKMYGPQP
                     VIGLDPAFAEDRVAALARTYPHVVVKDHVVPMAMIDHACRAGSWGTDLIESHRHLLGMA
                     ERHAQKHPGWRPTRRPTPGVDALRDLSPGYEISAVNETGSDIYALHDWLEELETLSEAM
                     EWPHPERDFTPGSLAGVEAELLQDHHRDTPASDDDSFHEYPAYLGEVLLRLAGGRWGWY
                     ADPALRSDGTAVIIPDPALGLDAIAPRLVAHHAIRARTGREFTALYDRVREAVQAYRAG
                     HPGWEPVRGEVPERPDWGDNPRLNTWLAEREAAFPAWAEEAGGEEVWDFSAESLDRLEA
                     LVREMFSTYKDMIAREDEPFLVGAAWYYGEVQVRLCGAVWQCRPEAEEDLPNDPFLVKG
                     EDADADSDTDTDTDADPDTDTDTDSVEDDEYDEDVEDDEGVCVVSSPPDELRALLRRGE
                     KYRLRDVLSRYSQGLSQTCSRLS"
     gene            20256..20642
                     /locus_tag="KI385_RS24540"
                     /old_locus_tag="KI385_24605"
     CDS             20256..20642
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987126.1"
                     /locus_tag="KI385_RS24540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24605"
                     /product="VOC family protein"
                     /protein_id="WP_238574284.1"
                     /transl_table=11
                     /translation="MTEEFDKATRAARVKCAAFWGHSGKALADFYAAALGWRVTQTYGD
                     TAAMISDGTTSYVFYTAEQFKAPNWPADELVFHLDLAFDDVAAAERRLISLGATKPEHQ
                     PGGAHWTVLLDPSGQPFCISAARS"
     misc_feature    complement(20773..20786)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.86"
                     /tool="antismash"
     gene            20774..21592
                     /locus_tag="KI385_RS24545"
                     /old_locus_tag="KI385_24610"
     CDS             20774..21592
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014177776.1"
                     /locus_tag="KI385_RS24545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_24610"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_238574285.1"
                     /transl_table=11
                     /translation="MRMFGRRCGSAATGAKRGDLGLERTPDALTLAGVGREYRRGVVAL
                     HPVDLAVPRGRFLAVMGPSGSGKSTLMQCAAGLDRPTVGTVRIGGTELSSLKEAALTRL
                     RRERVGFVFQAHNLVPSLSVVENVALPLLLGGEDAGERARRGLAAVGLGERGEAAPSEL
                     SGGQRQRVAIARALVTGPDIVFADEPTGSLDPATAQDVLALLRQAVDRDGHTVVMVTHD
                     PVAAAWADAALFLVRGRVVDRLERPEAAQVHEIMRDLGREQRYGREGCAA"
ORIGIN
        1 cttgcgatga gggcggctac gacgtcgggg tgcattcggg gatcgtcgcc ctcgcgctct
       61 ttggcgtcgg ccacgctgtt ccgttcgttc gcccgagtct ggagcgcgga cttcaccttg
      121 gcatcggtcg cctttgcggc cgcggcattc agtccggatg ccacttgcct ggaccgcgcg
      181 acaaagtctt tcgtcgcgcg catctctgtc ggctgttcct tggtgacgat gatctgtttg
      241 gcctcatcgc aaccggcggg cacaccgctc ccgctcgcca ccaccacgac ggtcgtggcg
      301 gccgcgacca ccacggcggc ggttcccgcc gtggcggcag tgttggcggt ggcgagtttc
      361 gcgaggtaac tgaacaggct gccgatcttc gccgtcggga cgacaggcgc ggcgacgagc
      421 gccagggccg cggccacagc gagcttgtcg cccttcagca ggttgctgat ctgctcctcg
      481 gcgctgacgt agtacttgag gtccttggtc attccgccgt gcgtcgcggc gaccttgccc
      541 aggacgtaga gccgcagcgc gatctgcccg cggccggctg ccagcgcggc cggcgcggcg
      601 gtcttgacca ggcgtgagac cagtacccac tgctgcgcct cactcagggc gcgcgcgacg
      661 atcagcagca gatacgggtc cggtcccggc ggcccggcct tcgcggcgag cgctgccgtc
      721 aggccttcag cggcggtggc cgccgcggtg ggggcccagt tctggttgcg gaccgcggcg
      781 gcggcgtcct cggtgagctg gtaggtgccg gcgctgtagg tgaccaggcg ccggtcgtag
      841 agttccggcc cggcgtccgc ggcccgtgga tctccggtga ccggtgcgaa ccaggcagcg
      901 gccagcggca cgccgaacgt cgccagcgcg accagcacgc tgcgggccgg ttcgctcagg
      961 gcgacggcca gggtctcggc ctgatgccgc gggctcagcc ggtccgggtc gaccggcggc
     1021 ggctggtcgt ggggctccct ggccgccctg gcacgccatt ggtcggagcc cttgatgaac
     1081 tccgcgtact ggcgcaggcg ttgaggcttg tcgtcggcca tccggtaggc gtggtcgaac
     1141 tgaaggttct gcagaccgac cgggcccagc gtcagcccga gttcggagct gagcagctcg
     1201 atcgcggcgg cccggggcag gggctggacc tggtgcgccg ccgcggtgtc cggcagcgtc
     1261 gggtacgggg acgtgaagag gaacgtgcag ccggagaagg tctgcagcac ccgggccacg
     1321 tcctcccggc tcagttcgca gtcgaagacg gtgacgtgta cgtcgcagac gtcggcgacg
     1381 gcctcgtgca gcatggtctc gtcgaccccg cgcaggaagg acttgccgaa gaacgcctcg
     1441 gccagccgct ggtagaggat ctccagcgtg ccggtctccc cggcccgggg tgacaggacg
     1501 tggccacgct gccctcgcgc cgccagcttg cggtgcaccg cctcggcgat cgccttcttc
     1561 ccgatgtccg cgggcccgta cagctggaca ctggtgccct cggtcagctg cctgaaggtc
     1621 tgctccacga tctcgtcgcg gccgaacagg tcggcctggg caggagcccg cagcggaggg
     1681 ggctcgcgca gcggcagttc cagcacgctc tcggtctcga cgaactttcc gtcggcgtag
     1741 atgacgttga gggtgtagtc acccgtgctc acattgccct ggacgtcgcc gtggaccacg
     1801 atcgatcgct cggcgccgga gcgggccgga tcctgggaca tgtgtgccgc aggcccgtcg
     1861 agcggcccgg cctcgccgct caccggcgct ggatgttgat cgcggcgtcc ccggtcgaca
     1921 cgatgccggg gacgttcccg gtcacagcca ccgcccgtgc gccgtcggcc tgcgccgccg
     1981 accgctcggg aagcagtgcc gccaactccg tgaccagcga cgggtcggcc gccagagctc
     2041 ctctgatctg aaggcgcagt gcggccagcg cgtccggatc accgtctgtt gtcgccaggg
     2101 tggtcaccgc cgcctcgatc ggtgcgcggt ccggagtgcg gcgcaggatc cggtcgagca
     2161 gccgctggcc cagccgtacc gtcgcatcgg ccgcctggtc ctcggcccgg ctcagcacat
     2221 tgacgccgta ggcgcccact gccgcaccga ccgccggcac gatctcgccg accagagaat
     2281 tgatgtcaga cactgttgtc ccccgttgtt gtctcaacga acagcagtca ggtgcgcaat
     2341 ggcgctccgc gatggcggct cttcccgaac ggcctccaga ccggccgcag tacgtctgcc
     2401 ccgggacacc gccggttact ccagtacacc cccgtcactt cgcacccggc aaccctgcgg
     2461 cttgtcgcgc aacggccgga atcggccatc cctcggtgcc gccaccgtcg gcgccgaggg
     2521 acaggccgaa gatgccagga cctagcccag cgcccgctcc aagctcccca gcgccgacgc
     2581 cagttcctcc cccgtgatgg tcagcggcgg ggcgagccgg attgtcgagc cgtgggtgtc
     2641 cttgaccagg attccttcct tcaggaggcg ttcgctgatc tcccggccgg tgccgagggc
     2701 ggggtcgatg tcgacgccgg cccacaggcc gcgggcgcgg aagccggtca ctcccttgcc
     2761 ggtcagtgcg gccaagccgg tgcgcagctg gtcgccgagt tcggcggcac ggcgctggaa
     2821 ctctccggtg gcgagcagct cgatgacggc cgaaccgacc gccgccgcca gcgggttgcc
     2881 gccgaaggtc gagccgtgct ggccggggcc cagcacgccg agcacctcgc ggcgggcgac
     2941 gaccgcggag accgggacga tgcccccgcc gagcgccttg ccgaggagga gtacgtcggg
     3001 gacgacggat tcgtggtcga cggccagggt ggttccggtg cggcccaggc ctgactggat
     3061 ctcgtcggcg atgaacagac agccggcccg ccgcgtcagt tcgcgtacgc cggtgagata
     3121 gcccgcgtcg gggatgacga cgccggcctc gccctggatg ggctcgatga gtacggcggc
     3181 cgtggtctcg tccacggcgg cttcgagggc ggcgaggtcg ttgtacggga cgacgcggaa
     3241 gccgggggcg aaggggccga agccggcgcg ggcggtctcg tcgttggaga agccgatgat
     3301 cgtggtcgta cggccgtgga agttgtcggc ggccacgacg atcgtcgccc ggtccgccgg
     3361 gacgcccttg acgtcgtacg cccacttacg ggcgaccttg atgccgctct ccaccgcctc
     3421 ggcgccggtg ttcatcggca gcaccatgtc caggccggtc agctcggcga ggccctcggc
     3481 gaaaccggcc aggcggtcgt tgtggaaggc gcgggaggtg agggtgagct gatcgagctg
     3541 gcggtgcgcg gcctcgatca gggccgggtg ccgatggccg aagttgagcg ccgagtagcc
     3601 ggccagcatg tcgagatagc gccgcccctc gacgtcctcg acccagacac cctcggcgcg
     3661 cgcgacgacc acgggcagcg ggtggtagtt gtgcgcgagg accggaccct cggcctggat
     3721 cagctccgcg gacgaacggg gcgcgtggac ggcggcggta cgggtgggag cggtcatgag
     3781 cggatctcct gggtgcagca cttgatgccg ccgccggcct tgcggaactc cgacaggtcg
     3841 acggggacgg ggacatagcc acgtgcggtg agctggtcga tgaggccggt cgcctgcggg
     3901 gcgatgaaga cctggcggcc gtcggagacg gagttgaggc cgaaggccat ggcgtcgtcc
     3961 cgggtggcga tcaccgcctg cgggaacagc cgccgcagca cctcgcggct gccggacgag
     4021 aacgcctcgg ggtagtaggc gatgttcgcc gcgccggtct ccgcgtcctc ctccaggacg
     4081 aagagcgcgg tgtccaggtg gtagaagtac gggtccacca gctggagccc gatcgtcggt
     4141 acgccgaaga actcctgcac ctcgtcatgg gcggcgcggg tggtacgaaa gccggtgccc
     4201 gccaggatgt agcggccggc cggtacgaga tcgccctcgc cctcgcagag cgactccggc
     4261 cggtagacgt cgtacccggc cgtcttgaac caggtttcgt actccgtgga ctccggtcgc
     4321 cgctgcggcg cgtggaagga cgagccgaag acccggccgc ccacgacgag cgccgagttc
     4381 gccgcgaaca ccatgtccgg cagaccggcg accggcgcca cgtgctccac cgtgtgtccg
     4441 tgcacgcggt aggcgcgcat cagcgtctcc cactgccgcc ccgccagcgc ggtgtcgacc
     4501 ggcgcctccg cacgcatcca ggggttgatc gcgtaacgca cttcgaagtg tctgggctcg
     4561 cagaccagat agcgccgggg gcgcgactca cgactcgtcg gcacagaaat atccctccgc
     4621 ttcctgcact tcctgtcatg acagaccgtt atggatagtc accaggggtg cttccacggt
     4681 aaggagcgcg ggattccggc cacaagaaat aaatgctgct tatcggcgca ggaatgctgc
     4741 gtatggacgg ctgtttctgg aggattcctg cgtcattcgg gggcggaaga ctggcgggcg
     4801 cccgcctccg ggctctccgg cagcagatgc gacagcacca tgtaactgat cgtcttgcgg
     4861 atgaacggct cggccctgat gcgttcgagc acctcctcga agtgctcgac atcggtcgcc
     4921 cgtacgtgca gcagcgcatc ggcgcccccg gtgacggtca tcgccgccgc gatctccgga
     4981 tggttgcgca cgacctccgc gagccgccgg ggcggggcgg cgctgtcgca gtacacctcg
     5041 acatacgcct cggtgagcca gcccagcgcg gccggccgca cggtcgcggt gaaccccgtg
     5101 atcacgttgt tctcccgcat ccggtccacc cgccgcttga ccgcggtgga cgacagcccg
     5161 acggccgcgc cgatctccgc gaagctcgcc cggccgttgt cgatcagcgc cgcaacgatc
     5221 ttgcggtcga ggtcgtcgaa gggcgcggcc ttgttggtca ctgaacctcc cgatccatcc
     5281 cggttcctcg ccatcgaggt cgcctcacgg tagcgatacc gtgcccgccg gtggcgcatc
     5341 ccccggtctg gccggcaaac ccccagctca ggcatctttg caggtcacgt ggggtggcgt
     5401 aacctcgcgg caacgccgct cgcctagcgt cggtgacccg ctgggggtaa gcgaggaggg
     5461 ccgggccgtg cgcgatccga gggagagcgg tggcgggtcc ggcgcggcgc cgacccgggc
     5521 ggaccgggcg cggcgggtgg cgcatgtgct gcggggacag gtgctgcgcg gggcctttcc
     5581 cgacggggtg ctgcccgatg aacgggcgct ggtggccgag ttcgacacct cccgcaacac
     5641 cgtgcgcgag gcgctggggc tgctgcgtga cgagggactg gtggcccggc gccagggtgt
     5701 gggcacggtg gtggtcgggc gcgcgtacca gcatccgctg ggggagctgt ccggtctggc
     5761 ggaggtgctc cagcggcacg gcgtggtcgt caacgaggtg cgcgaggcgc gcagcgtacg
     5821 gccgccgcgc acggtcgccc ggcggctggg gctggccgag ggcggtccgg ccgtctacct
     5881 ggagcggctg cgccgggtcg acggcacccc gctgtcgctg gactgcacct atctgatccc
     5941 cgaggtgggc gagccgctgc tggcgcgggg ccgggacacc ctggagaggc acgatgtctt
     6001 cgatctgatc gagaccgccg cgggtacgcc gctcggcacg gccgaggtgt ccgtacaggc
     6061 cgtggtcgcg gacccggcga cctgcgcggt gctcgcgatg cccgcgggcg gcgcggttct
     6121 ggccgtcgag cgcctcaccc ggctcgccga cggccgcccc gccgacctgg agttcattca
     6181 tctgcgcggc gaccggctga ccctgcacgc cacgctcgac cgggcgaggg gcggcccggg
     6241 cgccgcccac cgtcagccgt aggaggcggg gtcggcggcc gcccgggccc ggtgcacgcc
     6301 cggtggccta taccggctcc acccgctgca acttggcccg gcgtacgacc tccgggccga
     6361 gcttcgccgc ccgtgccacc agcgcgtggc cgtcccagtc cggcggccag ccgtgccaca
     6421 ggcgcagcgt gccgttgacg acgaccgcgg cgatctggtc gcggttcgcc aggcgaacaa
     6481 gttcccaccg caggtcgtag gagggcgtga gctcggggac ggcgaggttc acgacgagga
     6541 agtcggcggc cttgccggcc gcgatctcgc cggtcacctt gcccagcccg agtgcatcgg
     6601 cgctgcccgc ggtcgcatgc gtcagccacg tccgcccggc cccgcacacc gagtcgcccg
     6661 aggccatgcc gtatgccagc cgctgcgccg tctccccggc gtcgaccagc cggaagccgt
     6721 caccgcgggt gccgtcggtg cccatgccga atcgcacgcc catcgccgcc agcatggtcg
     6781 cgtgcgccac gccgttgccc ttccaggcgc tggccaccgg gttgtagctg atcgccgcac
     6841 cggagtcggc gagcagccgc atctccgaag gggtgaggag ggtggcgtgc gcgcccaggg
     6901 tgtgcggtcc gagcgcgccg atgtggtgca gatgttcgag cgggcgccgg ccgacgctct
     6961 tcaacgagcg ctccacggag gcgaggtgct cgttcacatg gatctgcagt accgcgccgg
     7021 cctcggcgca catgtcggcg gtcttcttga tgacctcgcc gggcgcgtcc tcagggacgg
     7081 cgatcgccag cgaggggtgg atcagcggat ggccctccca ccgtgccaga tgcgcggggc
     7141 cgcccgttcc ggtcgagacg atctcggaga gtacgcaccg gacaccggcc tcctccgtgc
     7201 ccttggccac cgccccgaca tcgacggggg cccgggttcc ggcatcggcg acggtggtga
     7261 agccgccccg cagagcctcc agcgcggcca gtttcgccga gagataggcg ctctcctcgt
     7321 ccagcgcatg ctccagcggc tcccagaccg tcttgaagat ctccgagggc tgcccgaagg
     7381 actgggcctt gccgaagctc tgggtcagat ggtggtgcgc gtcgacgaac ccgggcatca
     7441 gcaagtggcc gtccaggcgc accggttgaa gatcccggtg cgcggcgatg agctgttcgg
     7501 ccggcccgat ggtgcggaac ttcccgccgt cgaccagcac ggcctgcccg cgcaccggcc
     7561 cgtccggcag gagcagcagc tcgggcacca gcagctgccg ggtgccgtgg aagtgcgccg
     7621 gccgcaggcc gttgtccgtt ccgttcttcg tccgggcgtc gtgcggggcg gcggcatccg
     7681 ccgtgcccgg agcgtcgatt cccgatgcgc cgatgactcc gctcacgccg gccagaaacc
     7741 cacgccggcc gaagccgctg tgctgctcgt tcgccaaccc gctcgcctgc ttccgtactt
     7801 cggtacctgc gtacacctca ccgatccgtc cccggggtgg cccgacccta ggagcacccg
     7861 ggaagcggaa caagtgttcc ggcatacggg atttgtgagt cgggagggtg ggtggcgcaa
     7921 ccttcgccgg ggcccggcaa ccccctggtc atggcgtacg gaagtgacgc gaggggtggc
     7981 gtaacgtcgc cgaaacatca gccggtgccg ggcgcgcggg ccgcagggcc ccgcggatcc
     8041 ccgcatggga tcctggtgcg tcatggatct gccggacgga cggtggacgt gcggcgatga
     8101 cgaggatgcc ccgatgagac tctgcttcct ggtggaggag cagtaccgct acgacggcat
     8161 gccgctggac gtgatccgcc aactcggcgc ctggggccac caggtggacg tgctgtggcc
     8221 cggccgctca ctgatcccca tatccgaggc gatccaggcg ggcagccatg acgcctgggt
     8281 cctcaagacc gtctccggcg gaccgggcct gagccttttg gaagccgccg cgtgcgtcgg
     8341 actgacgacg gtgaacgacg tacgggcgat caggggcgtc cgcgacaagg cgctcgccgc
     8401 ggtgatcgcc cgcagtagcg gactgcccgt ccccgtgacg tatgcggcgg cccgggccga
     8461 ggagttcgcg cagatacccg aggcgcagta cccgctcgtg gtgaagcccg cggacggcag
     8521 ctcgggacgc gcggtgcggc tggtcgcgtc gccggaacag ctgctggacc aggcgctttc
     8581 cgcggaaccc ggggaagggg gcggggcggc cggcgggctg ctgatcgccc agccgtatgt
     8641 ccccaactcc ggtacggatc tgaaggtgta ctgcgtcgcc ggtgagctgt acgccaccga
     8701 gcggtgctcc ccgctgcacc cggggcgcgc cgtgcgtgag cgccaggtcc cgctcacacc
     8761 ggaagtcgcc cggatcgccg ccgagatagg cgcggtcttc ggcctcgatc tgtacggggt
     8821 ggacgtcctg ctcgggccgg acggcccggt ggtcgtggac atcaacgact tccccagctt
     8881 ccgccaggtg ccggacgcgg tcgcccgggt gtccgccgcc gtgctgcacc tcgcccgtaa
     8941 gggaccccgg cagccggtcg tggacctggc ctccccggca acggtcccgc tggccgcgat
     9001 cggcggtgac cgatgagggt cggtctgatc accgcggacc ccgctcaccc ggtgctggcc
     9061 gcggtcaccg ggctgctgac cccgcatcac cgggtggagc acctggaccc gggcggtgac
     9121 gtccaggacc tcgaccgcgg cgacctggcc gatgtctacc tcctcaaggc ccgtacgccc
     9181 cgggcgctgg ccctcgccgc caggctggag gggtacggcg ccccggtgat caactccgcg
     9241 gcggccaccg cgcggtgtca ggaccgggtg gagatggcgg cgctggcccg cgcggccggg
     9301 ctgccgttcg cacaaaccgc cctcgtggac gggctggggc agttggccac ggccggggaa
     9361 ccggccaccc cgctggtgat caagagccgc tacagccggc gccatgacct ggtgacccgg
     9421 gccgacagcg ccgcacggct gcgcgagctg gccgccgcct ggcccgatga gccggtggtc
     9481 gtccaggagt tcaccgcgaa cagcggttgg gaccacaagc tgtgggtggt cgccgggcag
     9541 ctcttcaccg ggctgcgccg ctcggaactg gcgccggacg gccgggggcc cactctgccg
     9601 ctgccggtcg acgagctgcc ggcgggctgg agcggcgccg cgctgcgggt gggcgaggtc
     9661 ttcgggctgg aggtctacgg cgtggacatc ctggacgccg gcggcggtgc gccgctgatc
     9721 gtggacatca acgccttccc cggcatccgc ggccaggccg gcgcccccga ggcgctggcg
     9781 gacctcgcac tccgtaccgc ggcacaagcc gaaagaacgg cgtcacaagc aagcctgaaa
     9841 tgatcatctc ccggagctga ccgatcccaa gacgccggga ggcggaacct cctcctccat
     9901 aaggcctagt gcgccgaccg gcggggtagc gctgcccccg tccgggaggc gtggttcagc
     9961 gcgccttcct tccgcacgta tggggaagag gccagcaacg gtgacgcagc catttgaact
    10021 gccgaacttc tatacgccct atccggcgcg gttgaacccg catctggaga cggcgcggac
    10081 gcattccaag aagtgggccc gcgacatgga gatgctggag ggctcgggca tctgggagga
    10141 gaaggacctc gacgcccacg actacgccct gctgtgctcc tacacccacc ccgactgcga
    10201 cgcggacgcg ctctcgctgg tgaccgactg gtacgtctgg gtcttcttct tcgacgacca
    10261 cttcctggag aagttcaagc ggacgctgga ccgggagggc ggcaaggagt acctcgaccg
    10321 gctgcccgcc ttcatgccga tggatctgac cacacccgta cccgagccga ccaaccccgt
    10381 cgaggcggga cttgccgatc tgtgggcgcg caccgtgccg cacatgtccc tggactggcg
    10441 gaggcggttc gccgagagca ccgagcatct gctcaatgaa tcgctgtggg aactgtccaa
    10501 catcaatatc caccgggtgc ccaaccccgt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgccccc tggtccgccg gcctggtgga gtacgcgacc ggcgccgagg tccccgcggc
    10621 cgtcgccggc tcccgggcgc tgcgggtgct gcgggacacc ttctccgacg gcgtacatct
    10681 gcgcaacgac ctgttctcct accagcggga gacggaggac gaaggcgagc tgagcaatgg
    10741 cgtcctggtg ctggagacct ttttgaactg caccacccag gaggccgccg acgccgtcaa
    10801 cgacctgatc acctcacggt tgcagcagtt cgagaacacc gtggtcgccg aactcccgcc
    10861 gctcttcgtg gagaagggcc tggacccgaa gtcctgcgcg gaggtgctgg cgtacgccaa
    10921 ggggctccag gactggcagt ccggcggcca tgaatggcat atgcgctcca gccgctatat
    10981 gaacggcggc gggtccgcgg ccggtacctc gctgccctgg tcgcccttct ccgtcggcgg
    11041 accgggcacc tcggcggccg acctcagaac ggccctggcc acggccggtg cgctccgctt
    11101 ccgcagctcc acccacgtcc cgcaccaaaa ggtcggcgcc tctcaaatcc ccgacatcca
    11161 tatgccgttc accaccaccc tcagcccgca cctggagggc gcccgccgcc gggtcatcgc
    11221 ctgggcgcac cggatgggca tccttcgccc gcagcccggc gtaccgctgt ccgacgtctg
    11281 ggacgagccc gcgatggccc ggcacgacct ggcgctgtgc gcggccggca tccacccgga
    11341 cgccaccccg gagcaactgg acctgagctc ggcgtggctg gcctggggca cctacgcgga
    11401 cgactactac ccgcaggtct tcggccggac ccgggacatc gccgccgcca aggtgtgcac
    11461 cgagcggctg tccgcgttca tgccgctcga accgtcggcc ggcacacccg aaccggtcaa
    11521 cgccctcgaa cgcgggctgg ccgacctgtg gacccgtacg gcgggaccaa tgaccctcga
    11581 agcgcgccgg atgttccgcg agaccatcga caagatgacg gccagctggc tctgggagat
    11641 cgacaaccag atccagaacc gcgtcccgga cccggtcgac tacatcgaga tgcgccgggc
    11701 caccttcggc tccgacctca ccatgagcct gagccgcatc gggcacggcc ggcaggtccc
    11761 gccggagatc taccgcaccg gccccctgcg ctcactggag aacgccgccg ccgacttcgc
    11821 ctgcctgatg aacgatgtct tctcctacca gaaggagatc gagtacgagg gcgaggtcca
    11881 caacggcatc ctggtcgtcc agaccttctt cggctgcgac tacccgaccg cgctgaacat
    11941 catcaatgat ctgatgacgt cgcgcatgca cgagttccag cacgtcgccg cccatgaact
    12001 ccccgtcgtc cacgacgact tcgacctctc gccggaggcc cgcaaggcgc tcgacggata
    12061 cgttcacgag ctggagaact ggatggccgg catcctcatc tggcaccggg gctgcctgcg
    12121 ctacatcgag cccgagctgc gccacccgcc gggctcgccg gggtggctgg gcgcgccgac
    12181 cgggctgggc acctcggcgg cccggatctt ccagcgggcg gtcgcgggcg tcgggtagtc
    12241 cgcagctccc gcagccccgc agcgctgggc ccgcagcgcc cgtgtccagg cccgtccttg
    12301 ccggctcccg aggcgacaag gacgggccgc gcgcctttcc gcagcatgcg cccgtgcccc
    12361 tcccgtgcgc gctaccacgt catgtgccac cgacctatgg ttcatgaccc cgtggacgcg
    12421 ggggcgagcg gcaagggggg cgagcgatgg cggcagggag cccgacaggc aggtcggccg
    12481 gcagttcggc atctcggcga gcgcaggaag cccgtaggca ggagcgcctg ttacgcgaac
    12541 agtggcaggc ggccagaagg caggccgagc ggtgggaggc ggcgagcgag ggggagcggc
    12601 gggtcgccgc ccagctgctg atgctcaccg agcgcggctg gcggctgctg gtggaccggc
    12661 gctggccggg cacccgcgcg gccaacgtgg acatgctgct gatcggcccc ggcggcgtct
    12721 tcgtcatcga cgtcaagaac tggcgggccg cgcccgaggc ctcggccggc cggctgcgcg
    12781 ccggcggatt ctcccgcgac gagcaccggc gcaagctgct cgcggtcacc aagaccgccg
    12841 agagcgcggt ggcctccttg gggatgtccc cggtggcggt gcgcccgctg atggccttcg
    12901 cggggcagcg cgtcgacacc gagctgggcc gggtacgcct gctgggcgag cacgagatcg
    12961 gcccggcgct gctgtcggag cgcacccggc tgtccgtcca gtcggtccgc gccctcgccg
    13021 aacatctggc gcgggccttc cccgagtacg aggccccgcc cgccgcccgg cccgcggtcg
    13081 tcggcgcccg cccgccggac gccgcgtccg acggcctctt cgacctcgac ggactgcggg
    13141 aggccgcgct cgacgaagcg cgccgggccc ccatcgagca atggatgacc ttcctcgacc
    13201 ccgaccagct cacactggta cgacgcaact gggccggccc cgcccggatc agcggcccgg
    13261 ccggcaccgg caagaccgtc gtcgccctgc accgcgccgc ctatctggcc caacgcacca
    13321 acggccgcat cctgtacgtc accttcgcca acaacctgcc ccgcgtccag gccaccttcc
    13381 tcaagaccat ggccccggcg gtggcggacc ggatcgagtt ccgcagcctg cactcctggg
    13441 cacaggagta cgtcagcggc cgcggtgtcc ccgtccgtct gcaccggaag aaggcggaga
    13501 ccgccttcag cctcgcctgg aagcacgtcg gccgggacag ctgcctcgcc gagatcgatc
    13561 cgctgcccca ttactggcag gaggagatca actacgtcat caagggccgc ggtatcgcct
    13621 ccttcgagga gtacgccgcg ctggtccgcc ggcgccgccg cgccggtctg cgccgcccgc
    13681 accggcaggc cgtctgggcc ctctacgagg cgtacgaatc cgagcgcgtc gagcgtgcgg
    13741 tgcacgactt caacgacgtc ctctcgctcg ccctggcgga ggcggccggc cgcaccggcc
    13801 acggtgccta tacggccgtc gtcgtggacg aggtccagga cctgaccctg gtcggggtgc
    13861 gtctgctgca cgccctggtc ggcgacagcc ccaacgggct gctgctggtg ggggacggcc
    13921 aacaggccgt ctaccccggc gggttccggc tctcggacgc cggtatcgac atccgcggcg
    13981 accgcgggca ggtgctgcgc gccaactacc gcaacagcaa ggagatcgtg gacaccgcgc
    14041 tctccgtcgt tgccgaggac tccttcgagg acctcgacgg actgcccacc ccgggccgcc
    14101 gggacgtcga tctgacctac cacgacggcc gggtgcaccg cgccgtgctg ccgaccccgg
    14161 ccgcgcacga cgaggccctg ctggccgcac tgcgcgccct gacaccccag cagctggccg
    14221 actccgccgt actctgcccc acccagcgcg ccatcgagcg ctaccagcgc ctcctcaccc
    14281 gggcgggcat cccggtctgc ccgctggaca ggtacgacgg gcacccggtc gcggccgtga
    14341 aactcggcag ctaccgccgc gccaagggcc tggagttcaa gcgcgtatac ctcccccggt
    14401 acgacgcggg ccggccggcc gacgcccagc acgggaccgc gtccgaaacc gcccgcgaac
    14461 gcggcgaact ggcccgcagt cagctcttcg tcgccatgac ccgggcccgc gacatgctgt
    14521 ggctgggcag cgtccggcca caacgggaac ggtgacccgg cggagccgct ctcctcgatc
    14581 gtcgggtgaa tgtgtcataa gtacggaata ttccgattcg gcatcgggaa ccccccatgg
    14641 cgaagtcccg caacgatccc gacctgggcg ccggaccgcc gccctggccg acaaggagtt
    14701 ccgtagatgc gacgcaagac cgctttcctt ggcgcggcgg ccctcaccac ggtgttcgcc
    14761 gtgctctgcc cgctcggcgc ccatgccgcc accggcgtca tcaccttcca cacccggccc
    14821 gggaacaggc cgcacgagat cctcgatccc ggcgacgacc actgctacgg cctgggggac
    14881 gcctacggcg aggtggacaa cgacaccggc gtcgacctcg tcctgtggac ctcccgcgac
    14941 tgcaccggga acgccctggc caccgtgccg gccggtacgg cggccacgat ggggcggtac
    15001 ggcagcctgc agctggccga ggtggagcct tcggacgagt ccgactccca ggagccttcc
    15061 gactaccgcg atccctcgga ctcccagggt ccctccgact cccgggatcc ctccgatgct
    15121 ccggacgagt cctacgctcc ggatccctcc gactccgggg acccctccga ctcccgggac
    15181 ccttccaact ctcaggaccc ctccgactct caggacccct ccgactacca ggacccttcc
    15241 gactctccgg ccgatgccga gtcgcctgcc cggtcgaact ccccggccgc ccccgaccgt
    15301 ccggccgtgt ccagctctcc ggccacctcc agctcgccgg cccgcttccg taagccgacc
    15361 aggccgggcg cccgcgccca cgtgctcacc ccctccgcga gcgactcgcc cgccgggtag
    15421 caacgcaccg tgccgacccg gcggcacacc acacctgtag cggccgcccg cgcgccggct
    15481 cgttggtgac ccagcgaatg gcgccggcgt acgggcggcc tcaccaggcc tgatggtcac
    15541 caggcctgat ggtcaccagg cctgatggtc accaggtctg tcggtcacca ggcctgttgg
    15601 tccgcgaacg cccggaaact gcggggcggt tggccggtga tgcgctcgac ggtgtcggtg
    15661 acgcggtcct cggcgccctc ggcgatggcc cggtccaggc cggccagcag tgcggcgaac
    15721 tcctcgggca tctcggcggc cagccggtcg cgctgctgct cgtaggtgag cggtcggtgg
    15781 cgtaccggcc ggcccgtgac cgcggtgagg gtggcggcga tgtcgtcgta actcagggcc
    15841 tgggggccgg tgatcaccag gtcggggccg ggcggcgccg gttcgtcgat gagggcgtgc
    15901 acggcgacgg cggcgatgtc gtccgcgtcg acgaacgcga cacggcccgt gcctgtagcg
    15961 gtcaggatgg tgccgtcggt gcggacgccc tgggcgtgcg gatggctgcc ggtgaagttc
    16021 tgcatgaacc aggagggccg cagcaccacc cactcgtcga acaggtccgg gagcgccgcg
    16081 tgcacctggc ccacccccgg gccaccggcg ggcagggccg aggagctgag gagcaccaca
    16141 cggcgcacac cggccgtacg ggcccgctcc aggaagggca gcatgacggc ggcggggtcg
    16201 ggtgcggcga ccggcggcac gaggtagagc cgggccgctc cgtccagggc gcggtggtgg
    16261 gtggcgggat cgtgccagtc gaagcggact ggccgggcgc cggcctgctg ggtggggtgg
    16321 cggccggcgg ccctgacggg gattccgagc gcggtgagcc ggggtacgag gcggctgccg
    16381 gtgttgccgg tggcgccggt gaccaggatg ggttcgcggt cgctcatgac gacttcactc
    16441 atgacgacgt cgcccatgac gacttcacct cggccatgga ggccgggacg gccaaggggt
    16501 tccagtagtc gcggtagtgc gtgatgcgac cgttcctgac cgtcaccacg gcgatgtagg
    16561 ccatctcgta cggcgcaccg gtggccacga tccgcccggt ggcgcgcatt tcgacgacga
    16621 tggtgtccgg ggcgtcggtc cggtggatct ccaggtgggg gaagtcctgg aggtcgatgt
    16681 gagtggggta gtcccgcatg tacgcggcga ccgccggcct gccgtcgagc cgcttgggga
    16741 agccgtccgg ggcgaagggg aactcgaaga cggcgtggtc gtcgcacagc gccacccagc
    16801 cgtcgatgtc cttgtcgagg agcagacgta ggccgtggcg gtagaggtct gtcggtgtgg
    16861 gtggtgcggt cggtgcggtg ttgccggtgc tcatgggggt gcctcctcgc ccctacactg
    16921 gggcgctata tggaccgctg gtccgcttga cttcgactat acggaccgtc ggtccgcttc
    16981 gtaaagggga gggctgatca tggccgaacg caaggcgcgt gcggacgcgc tccgtaaccg
    17041 cgagaccgtt ctggcggcgg ccgacgagct cttcgcccgc agcgagagcc cccgcagcgt
    17101 gtcgatggac gagatcgcgg cggcggcggg cgtcggcaag ggcacgctct tccggcggtt
    17161 cggcgaccgc accggtctga tccgtgcggt gttcgaagcc cggatcgagc cgctgcggca
    17221 tgccgtggag gcgggtccgg ccccgttggg gccctcggcc ccgccgcgtg agcgcgtacc
    17281 ggcgctgctc gacgccgtcc tgtgcttcaa gctcgacaac cggcatctct ccctcgcgct
    17341 ggaggaggcc ggcagcggca gcccgtatca ggcggcgcat tacgcgtggt ggcacggcat
    17401 cctgcgggac ctgctggagc ggatgcgcga cgcgacggac ggtgctgcgg gtggccctgc
    17461 ggacggcact ggggatggca ctgcggccgg tccggctccg gagagcgact tcacggcgca
    17521 cgccctgctg gccgccaccc gcgccgatct ggtcgaacac ctcgtcggcc aggaggggat
    17581 ggaccgcgag cggatcaggg cccgactggc ggccttcgtc ggcacggtcc tgggtcaggg
    17641 atagggatca cggggcaccg tgacgacgtc ggtgcggtgt gcccgcgctg cggcgaggcg
    17701 ttgcgccgca cccgcctcgc ggggcgcggg gcggtgtggt gcccccgctg ccggcccgaa
    17761 cagccgcact ggcccacgtg cgtcaggccg cctctcccgc ttccgcctcg ccggcctctc
    17821 ccgcctcttc ctccctgcac cacgccaggt aatccgccac cacctcgggc gggttggccg
    17881 cctcggtgag ggtctcctcg taccccgcgc ggtacatgtc gaagagcacg atcggaacgg
    17941 ggcggccgag gatctccgtg atccggccgc tggagtgcag atgccgtgcc aggtcgatgc
    18001 aggcctcgtc gaagtgcaac tccagcaact cgttccggac gctcacctcg tcgtcatcgt
    18061 cgtcatcggc ctcgccctcg tcgcccccgt cgtcctcgta ccagagcccg agctccttca
    18121 cctcggcggt gtgcagggcg gctccggtcg ggtcggccgg atcgtggccg atgaccccgg
    18181 cgatctcgtc cagcggccac cacgcgtagt tccaacgggc ctcatccgga tcagggtccc
    18241 gctgctctgc cggcacccgt cgtagctcgt cctcggtgtt gtagccgatc gcgagatacg
    18301 gatggcggtc gtcgaacgag tcattccgcc agatccggaa cgagaccaca tagatctgcg
    18361 gtctgagcgc ctccggaaac gcctccagcg cccgcgcgcc catgcgtcgc atgtggtcct
    18421 ggaacgtcat gtcccctccc cctatgacaa gcgcgaacac gtctgggaca agccctggct
    18481 gtagcggctc aggacatccc gaagcctgta cttctctccc cgccgcagca gcgcgcggag
    18541 ttcgtcgggc ggagagctga cgacgcaaac cccctcgtcg tcctcgacat cctcgtcgta
    18601 ctcgtcgtcc tcaaccgagt ccgtgtccgt gtccgtgtcc gggtccgcgt ccgtgtccgt
    18661 gtccgtgtcc gagtccgcgt ccgcgtcctc gcccttgacc aggaatggat cgttggggag
    18721 gtcctcttcg gcttccggac ggcactgcca taccgctccg cacagcctga cctggacctc
    18781 tccgtagtac caggccgcgc cgacaagaaa cggctcgtcc tcccgggcga tcatgtcctt
    18841 ataggtgctg aacatctccc gcaccagtgc ttcgagccgg tccagagact ccgcggagaa
    18901 gtcccacacc tcttccccgc cggcctcttc ggcccacgcg gggaaggccg cctcccgctc
    18961 ggccagccag gtgttcagcc gcggattgtc cccccagtcc ggcctctccg gtacctctcc
    19021 ccgtaccggc tcccaccccg gatgccccgc ccgatacgcc tgaaccgcct cccggaccct
    19081 gtcgtagagg gccgtgaact cccgcccggt gcgcgcccgg atcgcgtgat gggccaccag
    19141 ccgcggggcg atggcatcga gccccagggc cgggtcgggg atgatcaccg cggtgccgtc
    19201 ggaacgcagc gcgggatccg cgtaccagcc ccaccggccg cccgccagcc gcagcaggac
    19261 ctcgccgagg taggccgggt actcatggaa gctgtcatcg tccgaagccg gggtgtcgcg
    19321 gtggtggtcc tgcagcagtt cggcttccac accggcaagc gagccggggg tgaagtcccg
    19381 ttccgggtgg ggccattcca tcgcctcgga gagcgtctcc agctcttcga gccagtcgtg
    19441 caacgcgtaa atgtccgagc cggtctcgtt cacggcagat atctcgtagc cgggggagag
    19501 gtcacgcaac gcgtccacgc cgggtgtggg gcgccgcgtc ggccgccaac cggggtgttt
    19561 ctgggcgtgg cgctcggcca tgcccagaag atggcggtgg gactcgatca ggtccgtccc
    19621 ccaactgccc gcccggcagg cgtggtcgat catcgccatg ggcactacgt ggtctttcac
    19681 caccacgtgg gggtaggtcc ttgccagggc cgctacgcgg tcctccgcga atgcggggtc
    19741 gagcccgatg accggctgcg gcccgtacat tttcgtacgg gcccacgccc actcgccgcc
    19801 gatcgtgtcg agaatgatct cccctacgta ggcgcaggcg tccagggcga tccccgaggc
    19861 atccggcacc gatttctccc ggaacctgcc gagcaggaag acctccagag gttccagcga
    19921 gtccggggca agatcgaacg gaaaaccggt ggggagatgg atcttccgaa gacgttccag
    19981 ccgctgggat acggaagcga cccactgctc gatccgttgc tggggtgtgc cgctcggcgg
    20041 acctgggtgc gcgtcattct tcataccggc cgagcctaat gagccgcctg gatcagcggg
    20101 ccgcatcgcc gaacacgccg gcctgcaccc cgagatcggc cccgcagcgc gccccggcca
    20161 gccgtgacga cccgagccgc actgcctagg tcatcgtccg tcctagttgg ctcgtagcgt
    20221 cgctcgcatc gatgggagac aggagtggga acggcatgac cgaagagttc gacaaggcga
    20281 cccgggcggc ccgggtgaag tgcgccgcct tctggggcca cagcggcaag gcgctcgccg
    20341 acttctacgc ggccgcgctg gggtggcggg tcacccagac ctacggcgac accgcggcaa
    20401 tgatcagcga tggcacgacg agctatgtct tctacaccgc cgagcagttc aaggctccca
    20461 actggccggc ggatgagctc gtcttccatc tcgatctggc cttcgacgat gtcgcggcgg
    20521 ccgagcggcg gctgatctca ctcggcgcca ccaagccgga gcatcagccc ggcggtgcgc
    20581 actggacggt gctgctggat ccgtcgggcc agcccttctg catcagcgcc gcccggtcgt
    20641 aacggcccgt tggcccccac gtcctggtgg agtccgctac accaccagga cgggaccgtg
    20701 ctctctcccc ggcgcccgca ttcgtttcta gcgttctcgg tggcttggcg atctgtccga
    20761 ccactgagag ggcgtgcgta tgttcgggcg gcggtgcggt tccgcggcaa ccggtgcgaa
    20821 gcggggggac ctgggcctgg aacgcacacc cgatgcgctc actttggccg gggtcgggcg
    20881 ggagtaccgg cggggagtgg tcgcgctgca tcccgtcgat ctcgcggtgc cgcgtgggcg
    20941 gtttctcgcc gtcatggggc cgtccgggtc cgggaagtcg acgctgatgc agtgtgccgc
    21001 cgggctcgac cggccgacgg tggggacggt gcgcatcggc ggtacggagc tgtcctcgct
    21061 caaggaggcc gcgctcaccc ggctccggcg ggagcgcgtc gggttcgtgt tccaggccca
    21121 caatctcgtg ccgtcgctga gcgtcgtgga gaacgtcgcc ctgccgttgc tgctcggggg
    21181 cgaggacgcg ggcgagcggg cccggcgggg gttggcggcc gtcgggctgg gggagcgggg
    21241 cgaggccgcg ccgtcggagc tgtccggcgg gcagcgccag cgggtggcga tcgcccgggc
    21301 gctggtcacc gggcccgaca tcgtcttcgc cgatgagccc acggggtcgc tcgatcccgc
    21361 caccgcgcag gacgtgctcg ccctgctgcg gcaggccgtc gaccgcgacg gccacaccgt
    21421 cgtcatggtc actcacgatc cggtcgccgc cgcctgggcg gatgcggcgc tgtttctcgt
    21481 acgggggcgg gtcgtcgacc gtctggagag accggaagcg gcccaagtgc acgagatcat
    21541 gcgggacttg gggcgtgagc agcgttacgg gcgtgaaggg tgcgccgcat gagcgtgacc
    21601 aggctcctcg cctcccgcgc cgcgcgaacg catcgccggg catgggccgc cgtcttcgcc
    21661 gccctcgtcc tcacctccct gctgctcggc acgttcgggc tcacgctcgc ctcggccgcg
    21721 ctcgggcatc cgcgcgtgga gcggtacgcg gctgccgatc tcgtcgtcgc cggggaccag
    21781 aacacccgct tcaccgccaa gccgtggggc agcgagccgg agaccgcgga ggcagggctc
    21841 accgagcggg tgcgggttcc ggaggcggcc ctcgcggtgg tgcggaaggt gcccggggtg
    21901 cgggtggcca tcgccgacga ggtgttcccg gtagggctcg gcggggggaa ggcagccacc
    21961 gggcggccct ggggcgctgc ccggctggcg cacggtgccg tatgggaggg gcgggcaccg
    22021 cagcgtgccg gagaggtcgt ggtgagcggc ggggcccggg tgggtgaacg gatcgcgctg
    22081 cgtgcgggtg gcgccggggc gacgtactcc gggaactctg cgaactccgt gtactccgtc
    22141 gtcggggtcg cgggtggccc gcgtgacacc gtctacttca cagggagcga ggcccgccgg
    22201 ctggccgggc acccgggctc cctggacgcc atcgggat
//
