LOCUS       NZ_CP084681            22601 bp    DNA     linear   CON 30-APR-2024
DEFINITION  Streptomyces inhibens strain NRRL30439 chromosome, complete genome.
ACCESSION   NZ_CP084681
VERSION     NZ_CP084681.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces inhibens
  ORGANISM  Streptomyces inhibens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9696490)
  AUTHORS   Barry,C.P., Gillane,R., Talbo,G.H., Plan,M., Palfreyman,R.,
            Haber-Stuk,A.K., Power,J., Nielsen,L.K. and Marcellin,E.
  TITLE     Multi-omic characterisation of Streptomyces hygroscopicus NRRL
            30439: detailed assessment of its secondary metabolic potential
  JOURNAL   Mol Omics 18 (3), 226-236 (2022)
   PUBMED   34989730
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9696490)
  AUTHORS   Barry,C.P., Palfreyman,R. and Marcellin,E.
  TITLE     Direct Submission
  JOURNAL   Submitted (07-OCT-2021) EMS, Australian Institute for Bioengineering
            and Nanotechnology, Cnr College Rd & Cooper Rd, Brisbane, Queensland
            4103, Australia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. APRIL-2018
            Assembly Name                     :: AIBN_shyg
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 239.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_022221585.1-RS_2024_04_30
            Annotation Date                   :: 04/30/2024 04:58:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,775
            CDSs (total)                      :: 8,682
            Genes (coding)                    :: 8,305
            CDSs (with protein)               :: 8,305
            Genes (RNA)                       :: 93
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 377
            CDSs (without protein)            :: 377
            Pseudo Genes (ambiguous residues) :: 0 of 377
            Pseudo Genes (frameshifted)       :: 158 of 377
            Pseudo Genes (incomplete)         :: 310 of 377
            Pseudo Genes (internal stop)      :: 38 of 377
            Pseudo Genes (multiple problems)  :: 116 of 377
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:32:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 173503
            Orig. end                         :: 196104
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084681.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Australian Institute for
            Bioengineering and Nanotechnology, Building 75,Cnr College Rd &
            Cooper Rd, Brisbane City QLD 4072.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22601
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22601
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22601
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12601](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12601)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            <785..>1154
                     /locus_tag="KI385_RS00845"
                     /old_locus_tag="KI385_00840"
                     /pseudo=""
     CDS             785..>1154
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558180.1"
                     /locus_tag="KI385_RS00845"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="KI385_00840"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPQLIPVLDRIRPPRPAGEHPRTRPDHLCDNKAYSSRRNRQHLQR
                     RQIRHTVPERRDQRAHRQRRGIRAAHRPGSASRETLAGTKPSGQSACSRPSER"
     gene            1498..1767
                     /locus_tag="KI385_RS00850"
                     /old_locus_tag="KI385_00845"
     CDS             1498..1767
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI385_RS00850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KI385_00845"
                     /product="hypothetical protein"
                     /protein_id="WP_238570324.1"
                     /transl_table=11
                     /translation="MRAKTRTHRIVAALCAVPFLVLAGAGAASAAPAATPAAAPSSAWS
                     CNDWNRGSDCFDGGYGGYSHYGFDDYGFGYGYGNYGIAVVVLYG"
     gene            complement(2047..>2632)
                     /locus_tag="KI385_RS00855"
                     /old_locus_tag="KI385_00850"
                     /pseudo=""
     CDS             complement(2047..>2632)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612292.1"
                     /locus_tag="KI385_RS00855"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="KI385_00850"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="TWHDNLRLSDSTPLPCAASRETVKRSDLAGHAGYGYCRSHSRYFW
                     GFRLYLVTTAEGMPVTWCLAHPGLGEREVMTPLLERDRHLVHSGQVILADKGFAAGSSR
                     HSSPSACASIWCGRA"
     gene            complement(2944..4344)
                     /locus_tag="KI385_RS00860"
                     /old_locus_tag="KI385_00855"
     CDS             complement(2944..4344)
                     /GO_function="GO:0016702 - oxidoreductase activity, acting
                     on single donors with incorporation of molecular oxygen,
                     incorporation of two atoms of oxygen [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088671.1"
                     /locus_tag="KI385_RS00860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00855"
                     /product="carotenoid oxygenase family protein"
                     /protein_id="WP_238570325.1"
                     /transl_table=11
                     /translation="MTTTRNRYLSGNFAPVTEEVTAYDLPVTGRIPTHLNGRYLRNGPN
                     PLGIEDAAAHIWTLGAGMVHGVRIRDGRAEWYRNRWVRSGTVADHLGEPRRGTPIDEQL
                     DISPNVQVVGFAGSTFALIEGGIRPYELTYELETVGPCALGATPEGYSANAHSLFDPRT
                     RELHSLAFRYGSDNVQHIVMNDSGTVRRTTTIPVPGNPYMHDFALTDHYVLLFDSPVVF
                     SPAHLSTGVPFTWDDRRGARVGVLPREGGEVRWFGLTPSLVGHTLNAYERPHEDLRGSG
                     TGGCDIVVDVIRHPEGFDIRDVGSSRPTLDRWTIDLTAGTVREERLDDRVQEFPRLNSR
                     YTGRPYRYGYAAAVELYAPPTGPEDDRPDEGFSNALLKHDLSRGTTEAHEFGRDAAVGE
                     GVFVAAESPAAEDDGYVMAYVFNPERSASDLVILPAQDFSGEPIARIHLPVRVPLGLHG
                     SWVPGEDR"
     misc_feature    complement(3913..3915)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4341..4976)
                     /locus_tag="KI385_RS00865"
                     /old_locus_tag="KI385_00860"
     CDS             complement(4341..4976)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088672.1"
                     /locus_tag="KI385_RS00865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00860"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_238570326.1"
                     /transl_table=11
                     /translation="MSTLYQDALRAGQDAVRTTILDCAINLLVTDGPAALTMRRIATDI
                     GSSTKVLYTMFGGKEGLIDALYREGFARLRRVQEQVPRTEDPLTHLTHLGAAYREHALA
                     EPAYYRVMFEQTVPGFRPSAEALAIAETAFDTSAAAVAACMEAGVFQPGDAREVSKIFW
                     AASHGAVSLEIAGHFTPEDGGRRYDALMAAVARAFSTQHESKNEGQGT"
     gene            complement(5210..5842)
                     /locus_tag="KI385_RS00870"
                     /old_locus_tag="KI385_00865"
     CDS             complement(5210..5842)
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016994.4"
                     /locus_tag="KI385_RS00870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00865"
                     /product="erythromycin esterase family protein"
                     /protein_id="WP_342593416.1"
                     /transl_table=11
                     /translation="MRPMFVPAATMAKGARWLVCADKPGRPSEPHWSCRSRSRVVRAWS
                     RSMTTPDAADLGARDRHLADSVLQLLDRSAPDTRIVVTAHNAHIQRTVNRTVNPEGGSL
                     ARVPMGHPLVKELGAEYVSVALTSDGGRTVTNVPDPAHLAGMRQSAADAPQAPPDSVEA
                     LFVGVPEAPAMVETRALRTHAPRHGLPEPTRIRMDDGFLPVPALGRL"
     gene            complement(6077..7882)
                     /locus_tag="KI385_RS00875"
                     /old_locus_tag="KI385_00870"
     CDS             complement(6077..7882)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946994.1"
                     /locus_tag="KI385_RS00875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00870"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_238570327.1"
                     /transl_table=11
                     /translation="MKTSTARLVPRAMRFLRRRTRVLLLLAGWSLLESAHTFLGGYGVA
                     KALDDGFLTGHTGIGLAWLAVTALAVVIGGLAGRGVFRGLADLVEPLRDSLVRQVVARS
                     LTQAVAKPAHAADSAVVSRLTNQTEIARDSFAGLVLVARSFLFTAAGALLGLLSLAPQL
                     LLIVVPPLVAGLLLFLATLRPMAARQRTFLEADEALSTRFGAVAEGLRDVVACGAQEQT
                     AARAYGLIEDEARAARHLAGWAAVRCLALGLAGQLPILLLLVTAPWLLRQGITAGVVLG
                     ALTYLTQSLLPALHTLMNALGSAGTRLLVVLDRLTTDFGHEPATTSHSAPTTTPTTPTT
                     LAPAPAPAPAPIAPTPPNGPRVELRAVTFAYGPGAQPVLHDLDLTVQPGEHLVAVGPSG
                     IGKSTLTALIAGLLAPDHGEIRIDGRPVRAPSGPDPSLQRVLIPQQAYVFSGTLRENLL
                     YLCPDGASTSALESSSEAVGLGPLVHRLGGFDARIAPGSLSQGERQLIALGRAHLSPAP
                     LILLDEATCHLDPAAELRAERAFADRPGTLIIVAHRITSARRADRILLLDGTRATCGTH
                     DELLARSPLYRDLAGSWQPQALGRG"
     gene            complement(7879..9684)
                     /locus_tag="KI385_RS00880"
                     /old_locus_tag="KI385_00875"
     CDS             complement(7879..9684)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018890597.1"
                     /locus_tag="KI385_RS00880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00875"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_238570328.1"
                     /transl_table=11
                     /translation="MSRTPGPSSSPPPASLPASPPRPSATRRGPDAALGPVLTGALRHS
                     SVLTTAACLFSVASAGAAVALPAVLGHTLDLVLDSRPGGQAAIALCAVLLIAEVLLDAL
                     VALTGGVTTARSTAWLRRRGIDHLMSLAPHRVADHFTPGDLVTRLTGNAADAGTAPTTV
                     ATGLAALITPIGALIALALTDIWLAAVFLAGLPLLTWLLRTFARGSSDSVRRYQRVQAD
                     IATRLVEALGGARTIAAAGTERRERTRVLTPLRELGAQGRHMWQIYGRAVVSSSILVPL
                     LTTAVLAVGGIRLAHGSLTVGELLAASRYAALTAGLGGVVGQLNALVRSRAAAHRTGEL
                     LALPPVPHGSRPLPADGRGRLELRAVTVVRGGAAVLRGVDLVVPGGVTMAVVGHSGAGK
                     SLLAAVAGRLTDPDSGQVLLDGVPLSEADPAQLRREIGYAFERPVLFGETVGEAIGFGP
                     YEPPAHEIEAASRAAGADSFLRLLPDGCAAPLTRAPLSGGEVQRLGLARAFAHAGRLLV
                     LDDATSSLDSVTELHVSRALVHDVRTGSRLLIAHRVSSAARADLVAWMEHGRIRAVAPH
                     DRLWADPDYRAVFAHSGDEDTRAAS"
     gene            complement(9811..9939)
                     /locus_tag="KI385_RS00885"
                     /old_locus_tag="KI385_00880"
     CDS             complement(9811..9939)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="KI385_RS00885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00880"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_238570329.1"
                     /transl_table=11
                     /translation="MTLLDLQTMETPKAEATEELHTGSRASLLLCGDSSLSVTTCN"
     CDS_motif       complement(9877..9939)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTLLDLQTMETPKAEATEELH"
                     /locus_tag="KI385_RS00885_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9811..9876)
                     /prepeptide="core"
                     /locus_tag="KI385_RS00885_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="16.40"
                     /molecular_weight="1941.2"
                     /monoisotopic_mass="1940.0"
                     /core_sequence="TGSRASLLLCGDSSLSVTTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTLLDLQTMETPKAEATEELH"
                     /leader_location="[9876:9939](-)"
                     /alternative_weights="1959.2"
                     /alternative_weights="1977.2"
                     /alternative_weights="1995.2"
                     /alternative_weights="2013.2"
                     /alternative_weights="2031.3"
                     /alternative_weights="2049.3"
     misc_feature    complement(9912..9932)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.61"
                     /tool="antismash"
     gene            complement(10001..12601)
                     /gene="lanKC"
                     /locus_tag="KI385_RS00890"
                     /old_locus_tag="KI385_00885"
     CDS             complement(10001..12601)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551010.1"
                     /locus_tag="KI385_RS00890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00885"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_238570330.1"
                     /sec_met_domain="micKC (E-value: 7.6e-241, bitscore: 800.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 4.4e-13, bitscore: 48.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-08, bitscore:
                     32.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGYAVFCDADRQFYDAPHRLPTSGKGRGAPYATLSRDLPEGWQ
                     RHRSGDWLAFRPLDRELPSQGWKIHISACLDNAEQVLAKVWEYCVPRSVAFKCMPSRYL
                     LHIRNAKYADRGASGKFITVYPPDEERCRIIAEELDELLTGEPGPYILSDLRWGAGPVY
                     LRYGSFTERHCYDDKGELRPAIEDDRGQLVPDRREPAFRVPEWVTLPEFLEPHLAARSA
                     TTVTELPYAIEQALHFSNGGGVYVGRDLRTGQRVVLKEARPHAGLAADEADAVARLARE
                     RDALKRLSGLGCAPEVHDWFTLGDHTFLVLEFIEGRPLNSFFAHRHPLIEADPSPQRLA
                     EYTEWAMRVHELVADAVKAIHSRGVVFNDLHLFNIMMSEDESSVVLLDFEAAAVDDESS
                     RQVIANPGFVAPADRRGFDVDHYALACLRLALFLPLTSLFAVDRGKAAHLAQIAAEQFP
                     VPRDYLDEAVTEILRGHRPTSAPEHPDRRGGADYLPVSLGDWPHSRDSMVRAILASATP
                     DREDRFFPGDIAQFATAGGGTCFAYGAAGVLYALAETGAERCPEAEEWLLQRTKTPASG
                     SPLGFYDGLSGVAWVLDRLGHRDRALDLIDTLTAQSWQDIAPDLHSGLAGLGLALDSLA
                     GSTGERSLGDRALHCAQLVADKLQAGAPAAAGGATTRAGLLHGDSGAALLFLRLYERTD
                     DPALLDLAADALRRDLARCVRGAGGALQVNEGWRTMPYLGAGSVGIGMVLDDYLAHRPD
                     AEFERARGEIVQAAQAKFYAQPGLFRGAAGMVLHLSRTTAGGPGTFAADLRRQIDSLSW
                     GAIPYRGHLAFAGEQMMRLSMDLSTGTAGCLLALGSALHEIPVHLPFLPPPRRP"
     misc_feature    complement(11123..11125)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    12626..12638
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    complement(12685..12698)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.62"
                     /tool="antismash"
     misc_feature    12685..12698
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: strong, score: 23.62"
                     /tool="antismash"
     gene            complement(12914..13405)
                     /locus_tag="KI385_RS00895"
                     /old_locus_tag="KI385_00890"
     CDS             complement(12914..13405)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437091.1"
                     /locus_tag="KI385_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00890"
                     /product="hypothetical protein"
                     /protein_id="WP_238570331.1"
                     /transl_table=11
                     /translation="MKYVDLDAQVGGLTGVIDPTHYLGRLPELSGSLPPGALAFATDPH
                     HYSFSGKRCVKDLTLQQVSFLGNDGQDIEACFRHNCWKHDEDLVIRWTGVVDVRIETPD
                     GTSWSDLETVILDEILPHDHGCSHEMAFRPGTLMITCRDITATWVETDCPDARQGQGTS
                     "
     misc_feature    complement(13391..13405)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            13610..14737
                     /locus_tag="KI385_RS00900"
                     /old_locus_tag="KI385_00895"
     CDS             13610..14737
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669556.1"
                     /locus_tag="KI385_RS00900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00895"
                     /product="hypothetical protein"
                     /protein_id="WP_238570332.1"
                     /transl_table=11
                     /translation="MNVTLWAAGDLLGTELSDPVDLGGSEGNTVLRCRTAAGGSVIVKA
                     FTNEPEGLRSFTSEAAGLSLQLAGPALLGVDASVPLLVMEDLGGAPTLADVLLGDDPKA
                     AQEGLLAWGRGLGELAAASVHRRADLAQLRTQYDKGMVSWEDEPWIERNATDLLALLAG
                     AGIAVPRDLAGELARIGTVGGEEYPAFTPGDTCPYNALLTPDGLQLVDFESARFQSVFL
                     TAAYCRMPFANCWGVFSLPAWLAEEIEQAFRAGVVAAYPALGEDAVWEAGMRRAIAVWT
                     VDATVCLLPHTGEDGPLHPALRSVPTRRQVLRYRWESASALEDFPALAETMRLLLREVA
                     GRWDVGALPRYPAFADHDCDRRADGRWSDGVTGIR"
     misc_feature    14513..14515
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14859..15578
                     /locus_tag="KI385_RS00905"
                     /old_locus_tag="KI385_00900"
     CDS             14859..15578
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020554008.1"
                     /locus_tag="KI385_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00900"
                     /product="response regulator transcription factor"
                     /protein_id="WP_238570333.1"
                     /transl_table=11
                     /translation="MGVRAGQGRVLLVDDDAAIRRSLGRGLRLNGFAVDLADGGLGALA
                     KVADESPDVVVLDISMPDLDGIAVCRRLRSDGKDIPVLMLSALDEVADRVAGLQAGADD
                     YLVKPFALDELVLRLHALLRRRPPADTDAVRVGGLVLDAAARTARLDGRTVELTRREFE
                     LLEVLARNEGLVLTRDQLLDRVWGYDFEVRTDAVDTFVSYLRRKLEAGGRSRIVHTVRG
                     VGFVLRDDASGETGRRP"
     gene            15575..17065
                     /locus_tag="KI385_RS00910"
                     /old_locus_tag="KI385_00905"
     CDS             15575..17065
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006607859.1"
                     /locus_tag="KI385_RS00910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00905"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_238570334.1"
                     /transl_table=11
                     /translation="MRLSTRIAIVVGAVVPLLVVASGWVLVGLVTRDLRAQADQRLDER
                     ARTVATAARGLLRATSLGRPRAEQAHQRKLFSSALDVGFRLTGPYGTVMDGPQPGPAVR
                     LPARTEHPVTVRSHGKTWRALRVPVNGSQAGVNGTLWLFSPDTASQAQIQLVRSRVITV
                     AALAAPVSAALAWALAARAARPLRRLQQRTSGLDPHTTTARLEHTRTRITEVDDLAHTL
                     QTFLARYDEQATRTAEALATARSFSAAASHELRTPLMSMQTNLDILDAFQDLDPADRAE
                     TVDDLRRGHARLLGLLVMLRALAQGDLVEADAFAPVDLADLADASVSDLRRTRHEAAVT
                     LDSAPGLTVHGWQPGLRSLLDNLLANCLAHGRSADGRAHIAVTLRAAGDIDAPTAVLTV
                     DDQGPGVPPEQWQTIFERFHRRSDSPGSGLGLTLVAQQIALHRAHLRVLNGPGGQGARF
                     EITFPLTPADRPGAAVPVHRDWLSDTDQQRQEFHRERA"
     gene            17687..18166
                     /locus_tag="KI385_RS00915"
                     /old_locus_tag="KI385_00910"
     CDS             17687..18166
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI385_RS00915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KI385_00910"
                     /product="hypothetical protein"
                     /protein_id="WP_238570335.1"
                     /transl_table=11
                     /translation="MQRRKATLTATFSGLVLTGMMAVAIPSYAADSAPAAPPASVATHA
                     KDPQHASRHAKGPKGDGAKKLCRRVPKLERRIERRIKRMEGTVGTPGSIKFLEQRIANA
                     KKAHHSAIATFLGDRLTTRKTLLTSLKAKQPDLKDVATWCTANENGAKATASPAS"
     gene            18163..18396
                     /locus_tag="KI385_RS00920"
                     /old_locus_tag="KI385_00915"
     CDS             18163..18396
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI385_RS00920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KI385_00915"
                     /product="hypothetical protein"
                     /protein_id="WP_238570336.1"
                     /transl_table=11
                     /translation="MNRRRRLSLVVTAALAVPLLATTACSHSATPKDAAPPASSSPSVA
                     PDQLAQMQQKVDDAEHAADSADANGNADNSGN"
     misc_feature    18833..18848
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.55"
                     /tool="antismash"
     misc_feature    18835..18849
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.61"
                     /tool="antismash"
     misc_feature    18869..18885
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.76"
                     /tool="antismash"
     gene            18980..19300
                     /locus_tag="KI385_RS00925"
                     /old_locus_tag="KI385_00920"
     CDS             18980..19300
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601927.1"
                     /locus_tag="KI385_RS00925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00920"
                     /product="hypothetical protein"
                     /protein_id="WP_238570337.1"
                     /transl_table=11
                     /translation="MTTGIKGCDNQSNSYVSFVNEEHAGDSESVNPRSYSDAYAWISQH
                     KESPLSVQTGRGRCIIWDDDWKVKGQWDDGKGEFILASVQSSPQDYRMTVSNTGDISLS
                     AV"
     gene            19386..19619
                     /locus_tag="KI385_RS00930"
                     /old_locus_tag="KI385_00925"
     CDS             19386..19619
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KI385_RS00930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="KI385_00925"
                     /product="hypothetical protein"
                     /protein_id="WP_238570338.1"
                     /transl_table=11
                     /translation="MENRTGNWVYYICTAVQAFANLHFSRHVDNPSDDHMATNDGAYYY
                     YGVTGTFNQAAQQADQSVRQMLVDAWNDYFKV"
     misc_feature    19719..19732
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     gene            20197..20499
                     /locus_tag="KI385_RS00935"
                     /old_locus_tag="KI385_00930"
     CDS             20197..20499
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091475.1"
                     /locus_tag="KI385_RS00935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00930"
                     /product="hypothetical protein"
                     /protein_id="WP_238570339.1"
                     /transl_table=11
                     /translation="MKKSAIAGGCILGLLIIVGACKVSAATNDPLTLAEFDKIKAGSSE
                     KTLLQYASTCQQDGEAEPAHSDAATWTCFGADGSSNAVFFYSEGELFSKAQTGLV"
     gene            complement(20589..21515)
                     /locus_tag="KI385_RS00940"
                     /old_locus_tag="KI385_00935"
     CDS             complement(20589..21515)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091544.1"
                     /locus_tag="KI385_RS00940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00935"
                     /product="PhzF family phenazine biosynthesis isomerase"
                     /protein_id="WP_238570340.1"
                     /transl_table=11
                     /translation="MTTQTSAAGASPLPDTTLAASDTIDVLRYSAFTADPAGGNPAGVV
                     LDAEALDDQQMLAVAARVGYSETAFVTAGDTEARRYRLRYFSPRDEVAFCGHATIATAV
                     ALASRTGTGELVFDTPAGEIRVGTTTEGGLIRATLTSVPTHSHPAEEALVESVLRALRW
                     SRDELDADLPPHVAFGGNDHLVLAVRSRERLAALDYDFDALHDIMRHHGWTTVHLVHRQ
                     APDRLDFHARDPFPVGGVVEDPATGAAAAAFGGYLRALGLVTEPLRVHIRQGEDMGRPS
                     DLYIDLRPDDPRVRVTGQAVAIPDPGQ"
     gene            21599..22504
                     /locus_tag="KI385_RS00945"
                     /old_locus_tag="KI385_00940"
     CDS             21599..22504
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091545.1"
                     /locus_tag="KI385_RS00945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KI385_00940"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_238570341.1"
                     /transl_table=11
                     /translation="MDTRLLRTFVTLARAGSFTAAARSLHLAQSTVTVQIRTLEKELGT
                     PLFDRMPSGTIPTRAGLRLLEEAEEVLDAVARLRAAASAAHGDAESGTVEGEVAVGAGD
                     SLCSSRLPAVIASLRRSHPRLDVHLDAVSTAAAVDGLRTGRLDIALMLEPDVAENDLLA
                     RKIASEPLAYVAAPDHPLAGRAADWDELAHECFFLHEEGCSYSDRLVRTLLGLPGARPR
                     ITRFGSIDAARSCVAAGLGLTLLPHVTVERHLNEGRLAVVNGPDAEPVPVQLVRHRRRW
                     FSPGARVVTEELTRVFAAAP"
ORIGIN
        1 acctcggtgt tctgccgtac gccccggtag ggggagttct cgcgcaggac cccgtcgcag
       61 cgcatgccga gccgcttggc cacattgatg ctcgaagtgt tctcggagga caccagccac
      121 tccacacggt gcattccgcg ttcctggacc gcccagtcga tgatgacgca tgccgcgcgg
      181 gtcaccagac cgcgtccggc agcggccggt tccagccaac agccggcctc gcagttgccc
      241 gcagctgcgt cgaagaccct gaagaggacg ccgccgacga ggagtccgtc gagccagatg
      301 ccgtagagcc ggccggtgtc ggcagcggtc ttgtcggcgt acgactggag ccagctccgc
      361 gcggagtcga ggtcggctgc gacgtcgggg agcccgacgt gctggcctat gtattcgcgg
      421 ccgcggtcca tgtgggcgag gaattcctcg gcctgccagg gctccagtgg gcgcagctca
      481 gccccttcac ccagcgatat cgcgaacatt ctcgtcctcc atggtggccg tgcacggtcc
      541 ctggatcttc gcacggccat ctgcgcgttc gggggcagtc ccagacgctc acccgcccgc
      601 tttcgaaatg ccgcgttgcc ctcgattccc ggtgcggaaa ttccactgag gccggcgccg
      661 ggtcggtcag cgggtgggaa atggaatcgg acggctcggt cgccccacca gggaatcgag
      721 cctggacaat cgacgaagcc tgcatcgatc gaaaataccg ggcgagcacc ggaagggcag
      781 gcgagcaccg cagctgatcc cggttctgga ccgcatccgg ccaccccgcc cggccggaga
      841 gcacccacgg acccgaccgg accacctgtg cgataacaag gcgtacagct cccgccgcaa
      901 ccggcaacat ctgcaacgac gccagatccg acacacggtt cccgagcgca gggatcagcg
      961 ggcccaccgc cagcggcgtg ggatcagggc ggcccaccgg ccgggttcgg ccagccgcga
     1021 aacgctcgca ggaacgaagc cgagcggaca atcagcctgc tcaagacctt ccgagcgata
     1081 gcgacccgct tcgacaagcg tgcctacaca tttcacggca ccgtcgccgt tgccgccccc
     1141 ggctctggct ccgtccatat ccaccggaca gtcgataccc gccgggcagc ctttacccgc
     1201 cgggcagtcc ttggggcgtg tcctgggcgg cccgccgggc ggccccgcac cgtggccagg
     1261 cctgtgcgga gagcaatgtt tgaccttccc ggggcgccgt gcctacgctc gaaagcgacg
     1321 tctgattgag gttgcattga gattgcaact atgtcagcga agcaggtcgg agtcctgcga
     1381 agtcgccccg gtgcgccagg gcctcgcgcg ttcccggcgc acagcggtga ggccaggaga
     1441 actccatatt gatacgccga taaatcggca acgcatcaac cccgagaggg gacgatcatg
     1501 cgcgcgaaga ccaggacgca ccgcatcgtc gcagcgctgt gcgcagtgcc cttccttgtg
     1561 ctggccgggg ccggcgccgc aagcgcagct cccgccgcca caccggcagc cgcaccttcc
     1621 agcgcctgga gctgcaacga ctggaaccga ggctcggact gcttcgacgg cggttatggg
     1681 ggctacagcc actacggctt cgacgactac ggattcggct acggctacgg caactacgga
     1741 atcgccgttg ttgtcctcta cggctgatca tccggccgcg agcctcccga agaactccta
     1801 ccgcaggggg cctgccctca cgggccggcc ccctgccgct gcgccgcccc ggccgaacgg
     1861 acgccgagcg ccgagcaggg gtgtgcggac acctcacggg cttgtcgcgg atgcagtcct
     1921 tgaggaacga tccgatgtcg cacgcgagtt gcggacggag gagaccaatg gtcttcgccg
     1981 tagggggtgt ccggtgagtc gccaacgtcc catcggacag cccctggatg agtgagtccg
     2041 atgtcgtcag tggtcgtatg cgatcagtga tcgcttgacg ggggcgttgg tggtccagtt
     2101 gtgccagatg ccggctgcga gggccaggag gcgttgggcg gggcgagcga agacaccagc
     2161 aggtgttcgg ccccgtgttg ttccaggctg agctggcctt tgagggtgtc gaagacggcc
     2221 tcgatccact ggcggacttg ggccaggcgt ccgtttcgta caggctcgtt cctcaggccc
     2281 ggccgcacca gatggacgcg caggcgctcg gcgaggaatg cctcgaactc ccggcggcga
     2341 agcccttgtc cgcgaggatc acctggccgg aatggacgag gtggcggtcg cgttccagca
     2401 gtggggtcat cacctctcgt tcgccgagcc ctgggtgggc caggcaccat gtgacaggca
     2461 tgccctcggc tgttgtcacc aggtagagcc ggaatcccca gaagtagcgg gaatggctgc
     2521 ggcagtagcc atagcctgcg tggccggcca ggtcggagcg tttgactgtt tcccgggagg
     2581 cggcgcaggg cagtggggtg gagtcgctca gccgtaggtt gtcgtgccag gtgggcactt
     2641 gcttggcgcc cttcgccgtg gtcgcgacca gcacaaacat cggactcatt cgtctaggcc
     2701 cccagggccg gggcaggcag cgccctgaag cgtcctgcac ccctgaccac cgagcactga
     2761 gcatgaccgc tgagcaggtg cagccttgtc gccgccgtca cgtacgtggg cgggtacgcg
     2821 ggcaggtccg ccccaggcga cgacgcggcc tcatccggca actacaagcg gctcccagac
     2881 gacctacaac ccctcgttcc gggcgctacg gccaggccag gcagcccggt cgacggtccc
     2941 cgttcaccgg tcttcccccg gaacccagct cccgtgcaga cccaacggca cccgcaccgg
     3001 caggtggatc cgggcgatcg gttcgccgct gaagtcctgt gccgggagga tcaccaggtc
     3061 ggatgcggac cgctccgggt tgaagacgta cgccatgacg tacccgtcat cctccgccgc
     3121 cggcgactcc gccgcgacga acaccccctc ccccacggcc gcgtcccgcc cgaactcgtg
     3181 cgcttccgtc gttcccctgc tcagatcgtg tttgagcagc gcattgctga acccctcgtc
     3241 cggccggtcg tcttccgggc cggtgggcgg ggcgtagagc tcgaccgctg cggcgtagcc
     3301 gtaccggtaa ggtcggcccg tatagcggga gttgaggcgg gggaattcct ggacccggtc
     3361 atcgaggcgt tcttcccgga ccgtccccgc cgtcaggtcg atcgtccacc ggtccagtgt
     3421 gggccggctg gacccgacgt ccctgatgtc gaacccttcg ggatgccgga tcacgtcgac
     3481 gacgatgtca caaccgcccg tgcccgaccc gcgcaggtcc tcgtgcggcc tctcgtacgc
     3541 gttgagggtg tgccccacca ggctcggtgt gagcccgaac cagcgcacct cgccaccctc
     3601 gcgcggcagt acccccacgc gcgccccacg gcggtcatcc caggtgaacg gcaccccggt
     3661 ggacagatgc gcggggctga acaccacggg tgagtcgaag agcagcacgt agtggtcggt
     3721 cagcgcgaaa tcgtgcatgt acgggttacc ggggaccggg atggtggtgg tccgccgcac
     3781 cgtgccggag tcgttcatca cgatgtgctg gacgttgtcg gagccgtagc ggaaggcgag
     3841 cgagtgcagt tcgcgggtgc gcgggtcgaa gagggagtgg gcgttggcgc tgtacccctc
     3901 cggggtcgcc cctaaggcgc agggccccac cgtctccagc tcgtaggtga gttcgtaggg
     3961 gcggatgccg ccctcgatga gtgcgaaggt actgcccgcg aagcccacga cctgcacgtt
     4021 cggcgagatg tccaactgtt cgtcgatcgg ggtgccgcgg cgcggctcgc cgaggtggtc
     4081 ggcgaccgtg ccggaacgaa cccagcggtt gcggtaccac tcggcgcgcc cgtcccgtat
     4141 gcgcaccccg tggaccatgc ccgcgccgag ggtccagatg tgcgcggcgg cgtcctcgat
     4201 gcccagtggg ttggggccgt tgcggagata gcggccgttg agatgggtcg gaatccgccc
     4261 ggtcacgggc aggtcgtagg cggtgacttc ctcggtgacc ggggcgaaat tccccgacag
     4321 gtagcggttg cgcgtggtgg tcatgttcct tgcccttcgt tcttcgactc gtgctgggtg
     4381 ctgaacgccc gtgccacggc cgccatcagc gcgtcatagc gccgaccacc gtcctccggc
     4441 gtgaaatgtc cggcgatctc caaactcacc gcgccgtgcg atgccgccca gaagatcttt
     4501 gacacctcac gggcatcgcc cggctggaag accccggcct ccatgcaggc ggccacggcg
     4561 gcggccgagg tgtcgaaggc ggtctcggcg atggcgaggg cctccgcgct aggccggaag
     4621 cccggtacgg tctgctcgaa catgacccgg tagtaggccg gttcggcgag cgcgtgctcc
     4681 cgataggccg ccccgagatg ggtaaggtgc gtcaacgggt cttccgtacg aggtacttgt
     4741 tcctgaaccc ggcgcagccg cgcgaagccc tcccggtaca gcgcatcgat cagcccttcc
     4801 ttgccgccga acatggtgta gaggaccttg gtcgaggagc cgatgtcggt ggcgatccgc
     4861 cgcatggtca atgcggcggg cccgtccgtg accagcaggt tgatggcgca atcgaggatc
     4921 gtggtgcgca cggcgtcctg gccggcgcgt agcgcgtctt gatagagcgt gctcatgagc
     4981 aacactgtag cgcaacggaa acagtgttac cgccgcgcgc ctggtcggcc gcggttggta
     5041 aagacctcgc aggttcgggc ttcggcaatg tccccacgac cggtgggccc gtacagccat
     5101 cccgtacggc catcccctac aggccggtgc ggcgatgggc ccctggcggt aaggggccaa
     5161 ctcggccaag tccgcgctga gcgtggtgcg cgggacgctc accaccgcgt catagacgtc
     5221 cgagggcagg caccggcagg aagccgtcgt ccatgcggat gcgggtcggc tccggcagac
     5281 cgtgtcgtgg ggcgtgcgtg cgcagtgcgc gggtctcgac catcgccggc gcttccggca
     5341 cgcccacgaa cagggcctcc acgctgtcag gcggtgcctg aggagcatct gcagcggact
     5401 ggcgcatccc cgccaggtgc gccgggtccg gtacgttcgt cacggtccgg ccaccgtcgc
     5461 tggtcaacgc caccgacaca tactccgctc ccaactcctt gacgagcggg tgccccatgg
     5521 gcacccgagc aagggagcca ccctcagggt tgacggtgcg gttgacggtg cgctggatat
     5581 gggcgttgtg agcagtgacc acgatccggg tgtcgggcgc agaccggtcg agcagttgca
     5641 gcacgctgtc ggccaagtgg cggtcacggg cgccgaggtc ggcggcgtcc ggtgtggtca
     5701 tagaccggga ccaagcccga accacccgcg aacgactccg acaactccaa tgcggttcag
     5761 aagggcgtcc aggtttgtcg gcacacacga gccaacgggc gcccttcgcc atagtcgcgg
     5821 ccggcacaaa catcggtctc attcatccag tgctgtggcc gcacaggttc gccaggttgg
     5881 ggccgctggt cgagtgctgg ccgtctgcat gacgaagtcc tcgtcgtcaa ggctgagcag
     5941 gcgcggacgg cctcccatcc actcgcgtac atggacaggc tcccccacca ccgcgcctcc
     6001 agcggtcggg gaggtcatca ccgcacatcc ggcaccgctg ctaccaccgc cccggcgaac
     6061 ttatgcggtc acaggactag ccgcgtccca gtgcctgtgg ctgccagctt cctgccaggt
     6121 cgcgatagag cggcgagcgt gcgagcagct cgtcgtgggt gccgcaggtg gctcgggtgc
     6181 cgtcgagcag caggatgcgg tcggctcggc gggccgaggt gatgcggtgt gccacgatga
     6241 tcagggtgcc ggggcggtcg gcgaaggcgc gctcggcccg cagttcggct gccgggtcga
     6301 ggtggcaggt tgcttcgtcg aggaggatga gcggggcggg agacaggtgg gcccggccca
     6361 gcgcgatgag ctggcgctcg ccctgtgaca gtgagcccgg ggcgatgcgc gcgtcgaagc
     6421 cgccgagcct gtggaccagc gggcccagac cgacggcttc ggacgatgat tccagcgccg
     6481 atgtggatgc gccgtcgggg cacaggtaga gcaggttctc gcggagcgtg ccggagaaga
     6541 cgtaggcctg ttgcgggatg agcacccgct ggagggacgg atcgggtccg gacggggcgc
     6601 ggacgggacg gccgtcgatg cgtatctcgc cgtggtccgg tgcgaggagg cctgcgatca
     6661 gagcggtcag ggtcgacttt ccgatgccgc tcgggcccac cgcgacgagg tgctcgcccg
     6721 gttggacggt caagtcgagg tcgtgcagta cgggttgggc gccgggaccg taggcgaagg
     6781 tcaccgcgcg cagttcgacg cgggggccgt tgggcggggt gggggcgatg ggtgccggtg
     6841 cgggtgcggg tgcgggtgcc agtgtggtgg gggtggtggg ggtggtggtc ggcgcggagt
     6901 gggaggtggt cgccggctcg tggccgaagt cggttgtgag tcggtccagg accacgagca
     6961 gccgggtgcc ggcggatccg agcgcgttca tcagggtgtg gagggcgggg agcagtgact
     7021 gggtcagata ggtcagtgcg cccagcacga cgccggcggt gattccttgc cggagcagcc
     7081 agggcgcggt gaccagcaac agcaggatcg gcagttggcc tgccaggccg agcgcgagac
     7141 aacggacggc ggcccagccc gccaggtggc gtgccgctcg tgcctcgtcc tcgatcaggc
     7201 cgtacgcccg cgccgcggtc tgctcctgcg caccacaggc caccacatcg cgcagtccct
     7261 ctgcgacggc accgaaccgc gtcgacaggg cctcgtccgc ctccaggaag gtgcgctggc
     7321 gggccgccat cggccggagc gtggccagaa agagcagcag cccggcgacg agtgggggca
     7381 cgacgatcag cagcaactgc ggtgccaggg aaaggagtcc gagcagtgct ccggcggcgg
     7441 tgaagaggaa ggaacgggcg accaggacga gtccggcgaa gctgtctctg gcgatctccg
     7501 tctggttggt cagccgcgag accacggcgc tgtccgccgc gtgagccggt ttcgccaccg
     7561 cctgcgtcag tgaccgcgcg accacttgcc gtaccagact gtcgcgcagc ggctcgacga
     7621 ggtcggccag cccgcggaag actccccggc cggccagccc gccgataacg acggccagtg
     7681 cggtgacggc gagccaggcc aggccgatgc cggtatggcc ggtcaggaag ccgtcgtcga
     7741 gggccttggc caccccgtag ccgccgagga aggtgtgcgc ggactccagc agtgaccagc
     7801 cggccagaag cagcagtacg cgggtacggc ggcgcagaaa gcgcatcgcc cggggcacga
     7861 gtcgtgccgt tgacgtcttc atgaggcggc ccgggtgtcc tcgtcgccgc tatgggcgaa
     7921 caccgctcgg tagtcggggt ccgcccagag acggtcgtgg ggggccaccg cgcggatccg
     7981 gccgtgctcc atccacgcga ccagatcggc gcgggcggcg gaggagacac gatgggcgat
     8041 cagcaacctg ctgcccgtgc gaacgtcgtg caccagcgcc cggctgacgt ggagttcggt
     8101 gacgctgtcc aggctggagg tggcgtcatc gagcacgagc agacggccgg cgtgggcgaa
     8161 cgcccttgcc aggcccaggc gttgtacctc tcctcccgag agcggggccc gggtgagcgg
     8221 tgcggcgcat ccgtccggca ggagcctgag gaaagagtcc gcgccggccg cgcgggaggc
     8281 ggcctcgatc tcgtgggccg ggggctcgta gggaccgaag ccgatggctt ccccgacggt
     8341 ttcgccgaac aggaccggcc gttcgaaggc gtagccgatc tcgcggcgca gctgggccgg
     8401 atcggcctcg ctcagcggta cgccgtccag cagcacctgc ccgctatcgg ggtcggtcag
     8461 ccggccggcg acggcggcga gcagcgactt gcccgccccg gagtgcccga cgacagccat
     8521 cgtcactccc ccgggcacca ccaggtcgac accacgcagc acggcggcgc cgcctcgtac
     8581 aacggtgacc gcacgcagtt cgagccgacc acggccgtcg gcgggcagcg ggcgggagcc
     8641 gtgcggcacc gggggcaggg cgagcagttc gccggtgcgg tgggccgcgg cgcggctgcg
     8701 caccagggcg ttgagctggc cgaccacccc gcccagaccg gcggtgaggg cggcgtaccg
     8761 ggaagccgcc agcagctcgc cgacggtcag gctgccgtgc gccagtcgta tcccgccgac
     8821 ggcgaggacc gcggtggtca gcagcggcac caggatgctg ctgctgacca cggcgcgtcc
     8881 gtagatctgc cacatgtgcc gtccctgcgc gcccagttcg cgcagcggcg tgaggacgcg
     8941 ggtgcgctcg cggcgctcgg tgcccgctgc ggcgatcgtc cgggcgccgc cgagcgcctc
     9001 gacgagccgg gtggcgatat ccgcctgcac ccgctgatag cgccggacgc tgtcggagga
     9061 gccgcgggcg aaggtgcgca gcagccaggt caggagcggt agcccggcga ggaacacggc
     9121 ggcgagccag atgtcggtga gcgccagggc gatcagggcg ccgatcgggg tgatgagcgc
     9181 ggcgaggccg gtggccacgg tggtgggtgc ggtgccggcg tcggcggcgt tcccggtgag
     9241 ccgggtgacc aggtcgccgg gggtgaagtg gtcggcgacg cgatgcggcg cgagggacat
     9301 caggtggtcg atgccgcgtc ggcggagcca cgcggtactg cgggcggtcg tgacgccgcc
     9361 ggtcagagcc accagggcgt cgaggagcac ttccgcgatc agcagtacgg cacacagcgc
     9421 gatggcggcc tggccgcccg gccgcgagtc gagtacgaga tcgagggtgt ggccgagtac
     9481 ggcgggcaga gcgaccgcgg cgccggcgga cgccacgctg aagaggcagg cggcggtggt
     9541 gagtaccgag ctgtgccgga gggctccggt caggacgggg ccgagggcgg cgtccggccc
     9601 gcgccgggtg gccgagggcc gtgggggcga ggccggcagg gacgcaggtg gcggggacga
     9661 ggagggcccg ggtgtacgag acatgcgggt agggacctcg cctccagggg atgggtacgg
     9721 gcacgggcgg caggccccgg gcggtgttgc cacccggggc tcgccgtgac cttctcgcta
     9781 cggaagccga ggctccgcgg caacgaggag tcagttacag gtggtgacgc tcaggctgct
     9841 gtcgccgcag agcagcaggc tcgcgcggct gccggtgtgg agctcctcgg tggcctcggc
     9901 cttgggggtt tccatcgtct gcaggtcgag aagggtcatg gtggttcctc tcatcaatgg
     9961 ggacggggtg tttcatgatc ggccccggct ggggccggct tcagggccgc cgtggcggcg
    10021 ggaggaaggg caggtgcacg ggtatctcgt gcagcgcgct gcccagggcg agcaggcatc
    10081 cggcggtgcc ggtgctcagg tccatggaga gacgcatcat ctgctccccg gcgaaggcca
    10141 gatgcccgcg gtacgggatg gcgccccagg acagggagtc gatctggcgg cgtaggtcgg
    10201 cggcgaaggt gccggggccg cctgccgtgg tgcggctgag gtggagcacc atgcccgccg
    10261 caccgcggaa caggccgggc tgggcataga acttggcctg ggcggcctgc acgatctcgc
    10321 cccgcgcccg ttcgaactcg gcgtccggac gatgggcgag atagtcgtcg agcaccatgc
    10381 cgatcccgac gctgccggcg ccgaggtagg gcatggtccg ccagccctcg ttgacctgga
    10441 gggcgccccc cgcgccgcgt acgcaacgcg ccaggtcccg gcgcagggcg tcggcggcca
    10501 gatcgagcag tgccgggtcg tcggtgcgct cgtacaggcg caggaagagc agtgccgctc
    10561 cgctgtcgcc gtgcagcagc ccggcgcggg tggtggcgcc gccagctgct gctggcgcgc
    10621 cggcctggag tttgtcggcc accagctggg cacagtgcag ggcacgatct ccgagggagc
    10681 gctcgccggt ggaaccggcc agggagtcga gcgccaggcc gaggccggcc agtccgctgt
    10741 gcagatccgg ggcgatgtcc tgccagctct gcgcggtgag ggtgtcgatg agatccaggg
    10801 cccgatcccg gtgtccgagc cggtccagga cccaggcgac gccggagagt ccgtcgtaga
    10861 agccgagcgg gctgccggac gcgggggtct ttgtcctctg cagaagccac tcctccgcct
    10921 ccgggcaacg ctccgctccg gtttcggcca gggcgtagag cacgccggct gccccgtagg
    10981 cgaagcaggt gccgccgcct gccgtggcga actgggcgat gtcaccgggg aagaagcggt
    11041 cctcccggtc aggagtggcc gaggcgagga tggcgcggac catggaatcg cggctgtgtg
    11101 gccagtcgcc gagggacacg ggtaagtagt ccgctccccc gcgccggtcc gggtgctcag
    11161 gtgcgctcgt gggccgatgg ccccgcagga tctcggtcac cgcttcatcg aggtagtcgc
    11221 ggggcaccgg gaactgttcc gcggcgatct gtgccaggtg tgccgccttg ccgcggtcca
    11281 cggcgaacag gctggtgagc gggaggaaca gcgccagacg caggcaggcg agggcgtagt
    11341 ggtcgacatc gaagccccgg cggtccgcgg gggcgacgaa gcccgggttg gcgatcacct
    11401 ggcggctgga ttcgtcatcg acggcggcgg cttcgaagtc caggagcacg acggaggatt
    11461 cgtcctcgga catcatgatg ttgaagaggt gcaggtcgtt gaagaccacg ccccgtgagt
    11521 ggatcgcctt caccgcgtcc gccaccagct cgtggacgcg catggcccac tcggtgtact
    11581 ccgcgaggcg ctggggactc gggtcggcct cgatcagcgg gtggcggtgg gcgaagaagc
    11641 tgttcaacgg ccggccctcg atgaactcca gcaccaggaa ggtgtggtcg ccgagggtga
    11701 accagtcgtg tacctcaggg gcgcagccga gcccggacag ccgtttcagg gcgtcccgct
    11761 cacgcgccag ccgggccact gcgtccgctt catccgccgc cagaccggcg tgcggacgcg
    11821 cctccttgag caccacccgc tgaccggtgc gcagatcccg gccgacgtag acaccgccgc
    11881 cgttggagaa gtgcagcgcc tgctcgatcg cgtacggcag ctcggtgacg gtggtcgcgg
    11941 agcgggcggc gaggtgcggc tccaggaact ccgggagggt gacccactcc gggacacgga
    12001 aggcgggttc cctgcggtct gggaccagct gaccgcggtc gtcctcgatg gcggggcgga
    12061 gttcgccctt gtcgtcgtag cagtgccgct cggtgaagct gccgtagcgc aggtacaccg
    12121 gaccggcgcc ccagcgcaga tcgctgagga tgtacgggcc cggttcgccg gtgagcagct
    12181 cgtccagctc ctcggcgatg atgcgacatc gctcctcgtc gggcgggtag accgtgatga
    12241 actttccgct ggcgccgcga tcggcgtact tggcgttgcg gatgtgcagc agatagcggc
    12301 tgggcatgca cttgaaggcc accgagcgcg gcacgcagta ctcccagacc ttcgccagca
    12361 cctgctcggc gttgtccagg caggcggaga tatggatctt ccagccctgg ctggggagtt
    12421 cacggtccag gggacggaac gccagccagt caccggagcg gtggcgctgc cagccctccg
    12481 gcagatcccg gctgagcgtc gcgtacggcg cgccacggcc cttgccgctc gtcggcagcc
    12541 gatggggagc gtcgtagaac tgccggtctg cgtcgcagaa gacggcataa cccttgttca
    12601 tcccactccc tcggctggtg acaccacgac gctgtcacgc cagcggggcc ggaaacagtc
    12661 atgactgtca cgaggaaccc gtgagaaacg catgtttgcc gagtaggtga gcgagtaacc
    12721 ggggccgccg tcgatcagtg ccctgtcgcc atccggtcat tccctgactg agccggaggg
    12781 tggctgagga gtacggcagc gcaaggcgac ccccatggga gcggcgtgcg tacgcaggcc
    12841 tccctcagag cggcaagtgc aacggactct ggccccgccg ccaacaagca ctcggcgctg
    12901 agggggcggt ggctcagctt gttccttgac cttggcgggc gtcagggcag tccgtctcga
    12961 cccaagtggc ggtgatatca cgacaggtga tcatcagggt tccgggtcgg aaggccatct
    13021 cgtgagagca gccgtggtcg tgcgggagga tttcgtccag gatcacagtt tcgagatcgg
    13081 accaggaagt accgtccggc gtctcgatcc ggacgtcgac gacccccgtc cagcggatca
    13141 ccaggtcttc atcgtgcttc cagcagttgt gccggaagca ggcctcgatg tcctgtccgt
    13201 cgttgccgag aaagctcacc tgctgcagcg tcaggtcctt gacgcaccgc ttcccgctga
    13261 agctgtagtg atgcgggtcg gtggcgaagg ccagagcccc gggaggcagg ctcccgctga
    13321 gctcgggcag ccggcccagg tagtgggtgg ggtcgatgac tccggtcagg ccgccgacct
    13381 gcgcgtcgag atcgacgtac ttcatcacac actcctggct gtccctcgct gcaagatcaa
    13441 cgggtgtcat cgtggcatac ctcgccacca tggtgcccgg gcatttccgc tccgtgagca
    13501 ctgacctcgg ccggcctgcg gacccgcatc gttgcgacgg caagggcagt cggtatggcg
    13561 attggccggt cagaaggggc gcccgaagca gcagtgccag gatgccgaga tgaacgtgac
    13621 actgtgggcc gcgggagact tgctgggtac cgagctgtcg gacccggtcg atctgggtgg
    13681 cagcgagggc aacaccgtgc tccgctgccg gacggcagcc ggcggcagcg tgatcgtcaa
    13741 agcgttcacc aatgagcctg agggacttcg ctccttcacc tctgaggcgg ccgggctctc
    13801 gcttcagctg gccggtcctg cgctgctcgg cgtggacgcc tcggtaccgc tgctggtgat
    13861 ggaggatctc ggaggtgcgc cgacgctggc ggacgtactg ctcggggacg atccgaaggc
    13921 cgcacaggag ggattgctgg cctggggccg cgggctcgga gaattggccg ccgcatcggt
    13981 gcacaggcgc gccgacctcg cgcagctgcg gacccagtac gacaagggca tggtgtcctg
    14041 ggaggacgag ccgtggatcg agcggaacgc caccgacctg ctcgcattgc tcgccggcgc
    14101 cggaatcgcg gtgccgcggg atctggccgg agagttggcc cggatcggga cggtgggcgg
    14161 cgaggagtac ccagcgttca ctccgggcga cacctgccct tacaacgcac ttctcacccc
    14221 ggacgggttg cagctggtcg acttcgaatc cgcccgcttc cagtcggtct tcctgacggc
    14281 cgcgtactgc cggatgccgt tcgccaactg ctggggtgtc ttcagcctgc cggcctggtt
    14341 ggcggaggag atcgagcagg cctttcgcgc gggggtcgtg gcggcgtatc cggcgctggg
    14401 tgaggatgcg gtgtgggagg ccgggatgcg gcgggcgatc gcggtctgga cggtcgacgc
    14461 gacggtgtgt ctcctgccgc acaccgggga ggacgggccg cttcacccgg ctttacggtc
    14521 ggtcccgaca agacggcagg tgctgaggta tcgctgggag tcggcgagcg cgctggagga
    14581 ttttccggca ctcgcggaga cgatgcggct gctgctgcgg gaggttgccg gcagatggga
    14641 cgtgggcgcg ctgccgaggt atcccgcctt cgcggatcac gactgtgacc ggcgggcgga
    14701 cgggcgatgg tcggacggag tgaccggcat ccggtgagac ggccggccgg tggcgcccgc
    14761 tgccgggccg caggcggtgg gcggtaggcg gtaggcggta ggcggtaggc ggtagcgcat
    14821 gatggccgag ttcgacgcag gtcacggtgg aggcgggaat gggtgtgagg gccggtcagg
    14881 ggcgggtctt gttggtggac gacgatgccg cgatccggcg gtcgctgggg cgcgggctga
    14941 ggttgaacgg gttcgccgtc gatctggcgg acggcggcct cggcgcgctg gcgaaggtgg
    15001 cggacgagtc gcccgacgtg gtggtcctgg acatctcgat gcccgacctc gacggcatcg
    15061 cggtgtgccg gcgcctgcgg tccgacggca aggacatacc ggtgttgatg ctctccgcgc
    15121 tcgacgaggt cgccgaccgg gtggccggcc tgcaggcggg cgcggacgac tacctggtca
    15181 agcccttcgc cctcgacgag ctggtgctgc gcctgcacgc gctgctgcgc cggcgcccgc
    15241 cggcagacac cgacgccgta cgggtcgggg gtctggtgct cgacgcggct gcgcgcaccg
    15301 cccgtctcga cggcaggacg gtggagctga cccggcgcga gttcgagctg ctcgaggtcc
    15361 tggcccgcaa cgagggcctg gtcctgaccc gcgaccagtt gctggaccgg gtgtggggat
    15421 acgacttcga ggtccgtacc gacgcggtgg acaccttcgt cagctatctg cgccgcaagc
    15481 tggaagcggg cggacggtcc aggatcgtgc atacggtgcg cggcgtcggc ttcgtgctgc
    15541 gcgacgacgc gagcggcgaa acggggcgcc ggccgtgagg ctctccaccc ggatcgcgat
    15601 cgtggtaggc gctgtcgtac cgctgctggt ggtggcttcc ggctgggtgc tggtcggcct
    15661 ggtcaccagg gatctgcgtg cccaggccga tcagcggctg gacgaacgcg cccggaccgt
    15721 ggccacggcg gcccgcggtc tgctgcgcgc gacttccctt ggccgtccgc gcgccgaaca
    15781 ggcccaccag cgcaagctct tctcctccgc cctcgatgtc ggcttccgcc tgaccggccc
    15841 gtacggcacc gtcatggacg gcccccagcc cggccccgcc gtgcggctgc ccgcccggac
    15901 cgagcacccg gtcactgtcc ggtcgcacgg aaagacctgg cgtgccttgc gggtcccggt
    15961 gaacggcagt caggccgggg tgaacgggac actgtggctg ttctctccgg acaccgcgag
    16021 ccaggcgcag atccagctcg tgcgcagccg ggtgatcacc gtcgcggcgc tcgccgcacc
    16081 ggtatccgct gccctggcct gggcgctggc ggctcgcgcg gcccggccac tgcgtcgcct
    16141 tcagcagcgc accagcggcc tcgacccgca cacgaccacg gcccgcctgg agcacacaag
    16201 gaccaggatc accgaggtcg acgacctcgc acacaccctg cagacgttcc ttgcccgcta
    16261 cgacgaacag gccacccgca ccgccgaggc cctggccacc gcacgctcct tctccgccgc
    16321 cgcatcccac gagttgcgca caccgctgat gagcatgcag accaacctcg acattctcga
    16381 cgccttccag gatctcgacc cagcggaccg tgcggagacg gtggacgacc tgcggcgcgg
    16441 acatgcccgc ctgctggggt tgttggtgat gctgcgggcg ctcgcccagg gagacctggt
    16501 cgaggccgac gcattcgcgc ccgtcgatct ggccgacctc gcggacgcgt ccgtgtccga
    16561 cctgcgccgc acccgtcacg aggccgcggt gacgctcgac agcgccccgg gcctgacggt
    16621 ccacggatgg cagcctgggc tgcgttcgct gctggacaat ctccttgcca actgcctggc
    16681 gcacggccgg tccgccgacg gcagagcgca tatcgccgtg accctgcggg ctgccggaga
    16741 catcgacgcc ccgacggccg tgctcaccgt ggatgaccag gggcccggcg tgccaccgga
    16801 gcaatggcag acgatcttcg agcgctttca ccgtcgctcg gacagccccg gctccggcct
    16861 gggcctcacc ctggtcgccc agcagatcgc cctgcaccgc gcacacctac gcgtgctgaa
    16921 cggccccggc ggccagggag cccgcttcga gatcactttt cccctcacac ccgcggaccg
    16981 gcccggcgcg gcggtgccgg tgcaccggga ctggctgtcg gacaccgacc agcagcgaca
    17041 ggaattccac agagaacgtg cgtagcttcc tccccgcgcg gacgggcgca gcgcccgcgt
    17101 cgcgcgaagg gaggacacca tgcgcataag taacgccgca gccctgttcg gggacgcgga
    17161 aatcgccgtg gcaggccgcc gccgcgtatc gctcctcggc cgatgctccc ccactgtggg
    17221 ccggtgctcc cgaagctgcc tgtgcgaaga cgttgtgcac gggcgccccc gataccacgc
    17281 cgcagtagtg gcggaagggg ccgtccaccg tcgcgtgccg cccgtgccgc ccgtgccgcg
    17341 aactcgccgc ggcagggccc gcgatgggtg gatcgccggg ctggcagcag ccggtctcgc
    17401 cgtggccacc ctcgtctgcg tcgccctggt caccgcggac ggcagcgggg tgcgcagagc
    17461 gggccccggc acgagtacca ccgctcctgc tgcggtgaat cccacggacg cggtcggacg
    17521 gacgactgaa ccgcccggca ggtgatccgg cccgcagggc gatccgcccg gcaggtgatc
    17581 tacccggact cacaaagaaa ccacaagaac ggctcctagc ttcgcgctcg catggcacac
    17641 acctgccgct gtttcccagc agcggcacac agatgggaga ctcctcatgc agcgtcgcaa
    17701 ggcgaccctg acagcgacct tctcgggcct cgtcctcacc gggatgatgg ccgtagccat
    17761 cccctcctac gcggcggaca gcgcacccgc cgcgccgccg gcctcggtcg ccacacacgc
    17821 caaggacccc cagcacgcct cccggcacgc caagggtccg aagggcgatg gcgcgaagaa
    17881 gttgtgccgc cgggtgccga agctggagcg ccggatcgag cggcggatca agcggatgga
    17941 gggcacggtc ggcacgcctg gctcgatcaa gttcctggag cagcgcatcg ccaacgccaa
    18001 gaaggcccac cactccgcca tcgcgacatt cctcggcgac cggctcacca cccgcaagac
    18061 gcttctgacg tcgctcaagg cgaagcagcc cgacctcaag gacgtcgcca cctggtgcac
    18121 cgcgaacgag aacggcgcga aggccaccgc gagccccgcg tcatgaaccg ccgccgacgc
    18181 ctttcgcttg tcgtgacggc tgcgctcgcg gtgcccctcc tggccaccac ggcttgctcg
    18241 cactccgcca cgccgaagga cgcggccccg cccgccagca gcagtccctc ggtcgctccg
    18301 gaccagctcg cgcagatgca acagaaggtc gacgacgccg agcacgctgc cgactcggcg
    18361 gacgcgaacg gcaacgccga caactccgga aactgacaac tgacaactga caaccgacga
    18421 cagctccgta accggacatc tgtcacctgc aatccgccgt ctgcgcccgt acggagaact
    18481 cccggcgcag gcggcacatt acgacgacgc cggtcacccg gtgacatccg aggaccgcac
    18541 ccgccgctgt gcccgacgta atcgctggcg gcgcccgtac gaccggcccc cgccctcacg
    18601 cgggacacct cacgcatcag caggacgtct cacgcatcaa tttcttatgc aattcggcgg
    18661 attcgggttg acgcaatgcc accgcaccac agtatgacat ccagcccctc ccatacactc
    18721 tcgtttactc cggtcctatc ccatcaccac cgcatctatg gccggccgac ttccttactt
    18781 actgtgcccc ttccgcaaga gcccccatcc ggccagcatc aacattccag ccaatgccca
    18841 tcgttttccc acaacaactc cgacgagccg gtagtttcct ttcagctccc ataacggagt
    18901 cagccgaaag cggcggtacg tagagggtcc tgggccatca cagcccggga gcgccatgca
    18961 ccagtgaaag gaaacccgca tgaccactgg aatcaagggc tgcgacaacc aatcgaactc
    19021 ctacgtgtca ttcgtcaacg aagagcacgc cggggacagt gagtccgtga acccgaggtc
    19081 gtacagcgat gcgtacgcct ggatctcgca gcacaaagag agtccgctga gcgtgcagac
    19141 cgggcgggga cggtgcatca tctgggacga cgactggaag gtgaagggcc agtgggacga
    19201 cggcaagggg gagttcatcc tcgccagcgt ccagagcagc ccgcaggact accggatgac
    19261 ggtcagcaac acgggcgaca tctccctgtc agcagtctga tccgaggtat cggacgcgca
    19321 aaaggcatcg gacacgaaag agggggaacg tagtgcccat gcagaactgg cgtatcacga
    19381 acgccatgga gaaccgcacg ggaaactggg tgtactacat ttgcaccgcc gtccaagcgt
    19441 ttgcgaatct ccatttcagc cgccacgtcg acaatcccag cgacgaccac atggcaacga
    19501 acgacggcgc ctattactac tacggcgtaa ccggcacatt caatcaggcc gcccaacagg
    19561 ccgatcagtc cgtgcggcag atgctcgtgg acgcctggaa cgactacttc aaggtgtagc
    19621 ccgggccgcc tgccacgccg gccgatccgc ggggtctttg ccgccccctg ttcccaccct
    19681 cttcacgggt acgacccggc acccaggccc cacgcgtggg catccgaatt gccgtgcggc
    19741 gcgcgcgtca taggaggagc ccccccggtc ggtcgatcag tcaccactac ggcccccgcc
    19801 cctctcccgg cgggggccgt cggcatgcct cggcctcccc cgagtggcga gggcgcgcca
    19861 aatagacttc cttccctgcc ggttcgtccg ccggcaccac ccgcagaaag gcaccgccat
    19921 gcccgaccag tgcgtaacac cgccgtccac ggcggcaccc gcgccatccc cctcgccgac
    19981 gtcgtagacg ccgccaactt cccatgacca gtaccagggc accggccaca tcccatgggc
    20041 gttcggtgag ctgggcctgc ccctgatgca ccgcgtacgc tggcgcggcc cgaaagaccc
    20101 aactcgtacc cgcccagaca gaactcgccg cccccacagc tagacccgcg cccgccggtc
    20161 caccccccaa cacccgcaaa aggaaacact ccaccagtga agaagagcgc catagccggc
    20221 ggctgcattc tcggcctgct catcatcgtc ggcgcctgca aagtcagcgc cgctaccaac
    20281 gaccccctga ctctcgccga attcgacaag atcaaggccg gcagcagcga gaagaccctg
    20341 ctccagtacg ccagcacctg ccaacaggac ggcgaagccg aacccgccca cagcgacgcg
    20401 gccacctgga catgcttcgg cgccgacgga agcagtaacg cggtgttctt ctactccgag
    20461 ggcgagctgt tcagcaaggc acagaccggg ctcgtatagg cctccaggcg ccggcctgcg
    20521 cctgccccgg acggcacccg ggtacggcgg gcgccggctg gtcaactccg ccatcgctca
    20581 accggttctc actgccccgg atccggaatg gcgacggcct ggcccgtcac ccgtacccgc
    20641 gggtcgtcgg ggcggaggtc gatataaagg tcgctggggc ggcccatgtc ctcgccctgc
    20701 cggatatgca ccctcaaggg ctctgtgacc aggcccaggg cacgcaggta gccgccgaac
    20761 gccgcggccg cggcgccggt cgccgggtct tccacgacgc cgccgaccgg gaaggggtca
    20821 cgggcgtgga agtcgaggcg gtccggggcc tggcggtgga cgaggtgcac ggtggtccag
    20881 ccgtggtgcc gcatgatgtc gtgcaacgcg tcgaagtcgt agtcgagggc ggcgagccgc
    20941 tccctgctcc tgaccgccag gacaaggtgg tcgttgcccc cgaaggcgac gtggggcggc
    21001 agatcggcgt ccagctcgtc ccggctccag cgcaaggcac gcagcaccga ctcgaccagg
    21061 gcttcctcgg ccgggtggga gtgggtgggc acgctggtga gcgtggcgcg gatcagcccg
    21121 ccctcggtcg tggtgccgac ccggatctcc cccgccggcg tgtcgaacac cagctcgccg
    21181 gttcccgtac gggaggcgag ggcgacggcc gtggcgatcg tggcgtgtcc gcagaaggcg
    21241 acttcatcgc gggggctgaa gtaccgcagc cggtaacggc gggcctcggt gtcgcctgcc
    21301 gtcacgaacg cggtctccga gtacccgacc ctggcggcca cggcgagcat ctgctgatcg
    21361 tccagggctt cggcgtcgag caccacgccg gccggattgc cgcccgcggg gtcggcggtg
    21421 aaggcggagt agcgcagtac gtcgatcgtg tcggaagcgg cgagggtggt gtccgggagc
    21481 gggctcgcac cggcggcgga tgtctgtgtg gtcatgcgtc cacgttgtca ctccgcggcc
    21541 atcgcgtcca acgatggttc ttgctcggct ccatcgactg acgcgatagc gtgcgggagt
    21601 ggacaccaga cttctgcgta cgttcgtgac tctcgcaaga gcagggagct tcaccgccgc
    21661 cgcccgctcg ctccatctcg cgcaatccac ggtcaccgtc cagatccgca ccctggagaa
    21721 ggagttgggg acccccttgt tcgaccggat gccgtcgggg acgatcccga cccgtgccgg
    21781 actgcggctg ctggaagagg ccgaagaggt gctcgacgcg gtggccaggc ttcgcgcggc
    21841 ggcatcggct gcccacggtg acgcggagag tgggacggtc gagggtgagg tcgccgtcgg
    21901 tgcgggtgat tcgctgtgtt cctcgcggct gcccgcggtg atcgcctcct tgcggcgcag
    21961 tcacccccga ctggatgtcc atctggacgc cgtcagcacg gccgcggcgg tggacggact
    22021 tcgcacgggc cgactcgaca tcgcgttgat gctggagccc gacgtcgccg agaacgatct
    22081 gctggcccgc aagatagcga gcgagccact ggcgtacgtg gcggcacccg atcatccgct
    22141 ggccggacgg gcggccgact gggacgagtt ggcccacgaa tgcttcttcc tgcacgagga
    22201 gggctgctcg tacagtgacc ggctcgtgcg gacattgctg ggtctgcccg gggcccgccc
    22261 ccggatcacc cgcttcggca gcatcgacgc cgcccggtcg tgcgtcgcgg ccggtctcgg
    22321 cctgaccctg ctcccccatg tgacggtcga acgacacctg aacgaaggcc ggttggcggt
    22381 ggtgaacggc cccgacgccg agcctgtgcc cgtccagctc gtccggcacc gcagacgctg
    22441 gttctcgccg ggtgcgcggg tcgtcaccga ggaactgacg cgcgtgttcg ccgcggcacc
    22501 ctgaccggct cctgaacgtg ccgttgccgc acgtcgagag tgcgaccacc gccaacggat
    22561 gcacatgctg ggaaaaatcc ggcgccagga ccgcggtcgg c
//
