LOCUS       NZ_CP091381            21107 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Amycolatopsis sp. FU40 chromosome, complete genome.
ACCESSION   NZ_CP091381
VERSION     NZ_CP091381.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. FU40
  ORGANISM  Amycolatopsis sp. FU40
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9944196)
  AUTHORS   Reisman,B.J. and Bachmann,B.O.
  TITLE     Biosynthesis of Apoptolidin Family Glycomacrolides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9944196)
  AUTHORS   Reisman,B.J. and Bachmann,B.O.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2022) Chemistry, Vanderbilt University, 1234
            Stevenson Center Drive; Room 7330, Nashville, TN 37235, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 23-JAN-2022
            Assembly Method                   :: Flye v. 2.9
            Assembly Name                     :: NFU40_flye_2.9
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 47.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021903635.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 04:30:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,491
            CDSs (total)                      :: 9,417
            Genes (coding)                    :: 9,360
            CDSs (with protein)               :: 9,360
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 7 of 57
            Pseudo Genes (incomplete)         :: 50 of 57
            Pseudo Genes (internal stop)      :: 5 of 57
            Pseudo Genes (multiple problems)  :: 5 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:13:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 629581
            Orig. end                         :: 650688
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP091381.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Brian O. Bachmann,
            Vanderbilt University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21107
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21107
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21107
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11107](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11107)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            362..811
                     /gene="sufU"
                     /locus_tag="L3Q65_RS04170"
                     /old_locus_tag="L3Q65_04170"
     CDS             362..811
                     /GO_function="GO:0005198 - structural molecule activity
                     [Evidence IEA]"
                     /GO_process="GO:0016226 - iron-sulfur cluster assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sufU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003071387.1"
                     /locus_tag="L3Q65_RS04170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04170"
                     /product="Fe-S cluster assembly sulfur transfer protein
                     SufU"
                     /protein_id="WP_037814681.1"
                     /transl_table=11
                     /translation="MNLESMYQEIILDHYKNPHGRGLRDPFDAESFQVNPTCGDEITLR
                     VKVSDGKVEDVSYDGQGCSISQASASVLTDLVVGHTVDEAFTTMDAFVELMQGKGKVEP
                     DEDVLEDGVAFAGVAKYPARVKCALLGWMAFKDAVSSTTTGAEKA"
     misc_feature    829..843
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            894..1292
                     /locus_tag="L3Q65_RS04175"
                     /old_locus_tag="L3Q65_04175"
     CDS             894..1292
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005463760.1"
                     /locus_tag="L3Q65_RS04175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04175"
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="WP_037814682.1"
                     /transl_table=11
                     /translation="MSEETATDPREGRTAADLPEQSAAVPADIAKIEDVEEAMRDVVDP
                     ELGINVVDLGLVYDIRVETDNTATIDMTLTSAACPLTDVIEDQTSAALTSGGLVNDFRI
                     NWVWMPPWGPEKITDDGREQLRALGFTV"
     gene            1416..1838
                     /locus_tag="L3Q65_RS04180"
                     /old_locus_tag="L3Q65_04180"
     CDS             1416..1838
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075918.1"
                     /locus_tag="L3Q65_RS04180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04180"
                     /product="hypothetical protein"
                     /protein_id="WP_182896108.1"
                     /transl_table=11
                     /translation="MTEPDSASVSSPGDRPGRGLAVAAVSVAAVSFALGVATWLAWLLV
                     RPRLLMGGIYPIVAEVFVLVLGALWFLAVLASVLAVVFGLLAGARRYGADLARLGALLG
                     GLAFVVALAGTVAFTSNPGFTTGQFDVRPTHATLGR"
     misc_feature    complement(1441..1458)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(2130..2144)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.0"
                     /tool="antismash"
     gene            2157..2927
                     /gene="lepB"
                     /locus_tag="L3Q65_RS04185"
                     /old_locus_tag="L3Q65_04185"
     CDS             2157..2927
                     /EC_number="3.4.21.89"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006465 - signal peptide processing
                     [Evidence IEA]"
                     /GO_process="GO:0009306 - protein secretion [Evidence IEA]"
                     /codon_start=1
                     /gene="lepB"
                     /inference="COORDINATES: protein motif:HMM:NF021981.4"
                     /locus_tag="L3Q65_RS04185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04185"
                     /product="signal peptidase I"
                     /protein_id="WP_237598814.1"
                     /transl_table=11
                     /translation="MTEGFPAAPPPAGRAPRRFSWVLAAFVVVALAGSVVAVTGLLKVF
                     SYRSLTVTGGSMANTVVSGERVVFGLREGQEIHRGDLVVFDASAFGDGRRGTFLQRVIA
                     VGGDEVECCDLERRIKVNRKSIDEPYVAGEQTPFYAKVPTGAVFLAGDRRDIADDSRWR
                     VNEPGGGAVSLSAVHGVVSATGNLFWVRQIPATTAFTAAGFPGTTEPDSGPVTGRITAG
                     AGAGLFLIGFAGLLGTVVRSAGRRRKAAAVPPAR"
     gene            complement(2842..4773)
                     /locus_tag="L3Q65_RS04190"
                     /old_locus_tag="L3Q65_04190"
     CDS             complement(2842..4773)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637159.1"
                     /locus_tag="L3Q65_RS04190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04190"
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="WP_182896106.1"
                     /transl_table=11
                     /translation="MQTLLLGLLAYVVVLWPLVAAARKVLGVRVGLVRALGAALAGWLV
                     AGTVIRLFPIAVLSNAGVAIGLLIPLAGSALAVTLLVLFVAELAVPSGGPGLFARMRSL
                     RSRAARARRYSRIMRIAIRHGLGSFLTGRRTAGPDGSAKLARSLRLALEEAGVTFVKLG
                     QLLSTRADLLPPVYIRELSKLHDQVPPAPEDEVRALLREEIDVTAFAHIDDEPLAAASI
                     AQVYGARLRSGAEVVVKVQRPGIREQVERDIDIVRRLADVLYVRAGWARSLGVRELADG
                     FAESLEDELDFRTEAANIEAIAAHPVPGVTLPAVHKVLSTERVLVMRRLDGKPLSAGSA
                     CSREELARTFLRGLLDQVLLGGVFHADPHPGNVLLLEDGTLGLLDFGSVGRLDTGLRAG
                     LQALLPAIDRGDPAGVRDGLLEIVNRPDDLDEQRLERALGALLARHFGPGRTPGLDLFT
                     GLFRVVADFRLAVPPPIAAVFRALATMEGTLATLAPNFDLVAESRAFATERIGLRPETL
                     RRTVTDEFTALLPVLRRLPRRVDRIGAALEEGRLSVNMRLFSDERDRDLVTGLVHEVLL
                     ALVGIATGLMAVLLLGSSSGPQVVPGLTLNHVFGYNLLMISALAGLRLLFVVFRRSGRR
                     SRADRRTR"
     gene            4947..5489
                     /locus_tag="L3Q65_RS04195"
                     /old_locus_tag="L3Q65_04195"
     CDS             4947..5489
                     /EC_number="3.4.24.-"
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658185.1"
                     /locus_tag="L3Q65_RS04195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04195"
                     /product="snapalysin family zinc-dependent metalloprotease"
                     /protein_id="WP_182896105.1"
                     /transl_table=11
                     /translation="MHARGFRRIAALAAATAAPLGFGLATAPAASAAAATTVYYSSAGA
                     PDYVAQIDQGAANWNAAVSDVRLVKDEGKATVKIHEVNSGGSYTQTDGHGNGDVYLDTS
                     QVAEGYDPTRIAAHELGHNLGLPDHYEGPCTELMSGHGPGTSCTNAKPDAQESAKVQQL
                     WANGFRIDGTRVTKTVY"
     gene            complement(5543..6268)
                     /locus_tag="L3Q65_RS04200"
                     /old_locus_tag="L3Q65_04200"
     CDS             complement(5543..6268)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018684664.1"
                     /locus_tag="L3Q65_RS04200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04200"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_182896104.1"
                     /transl_table=11
                     /translation="MPSEESTVINDYDLLAETYTAMSDTEIQNAYYERPAVLALAGDVA
                     GRRILDAGCGAGPLTVALRERGAEVSGFDLSSGMLEIARQRLGPDVDLRVADVAGPLPY
                     ADNAFDDVIASLVLHYLKDWGPTLTEFHRVLRPGGRLIVVVDHPYAIHLLQRQAGQQTD
                     YSATYEWTEDWEVGGRTTPMSFWNRPLHAMTDAFAEAGFRISTISEPKPVPEAEKLFPE
                     DYRMLCVSPSFLFFLLQAE"
     gene            6352..7551
                     /locus_tag="L3Q65_RS04205"
                     /old_locus_tag="L3Q65_04205"
     CDS             6352..7551
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075923.1"
                     /locus_tag="L3Q65_RS04205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04205"
                     /product="sensor histidine kinase"
                     /protein_id="WP_182896103.1"
                     /transl_table=11
                     /translation="MRFLRPLVSGVTYRRWVYLILGAALSVPYLLLAMIAMPSLMPFAT
                     TMGWASVAGFVVMLVVLAATAFLPAVRVLEAAAVRELLAQPAPGRGRLRCATMFVLHVV
                     AGLFTGLATLALPAGFGFAINAVFTGRLVDTPDFHLTVPRGWASAWLPAAFVAAFVVLI
                     YFVWALGGVLRRAAARLLGWSAAERIAQLERRTDQLAERTRLARELHDSVGHALSVVTL
                     QAGAARRTLHTDPGFTEEALTAIEESARTALDDLDHVLGLLRDEARDRTPHAGLANLPA
                     LITVTQQSGTECRVEVQGDVGAVPAVVSREVYRILQECLTNAVRYAGKVPVTVALAVAD
                     GQLRAAVANPLGSARPSRVRGGRGLRGMAERAELVGGKLSAGPVGENWEVVVTVPWGNR
                     "
     gene            7548..8192
                     /locus_tag="L3Q65_RS04210"
                     /old_locus_tag="L3Q65_04210"
     CDS             7548..8192
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637155.1"
                     /locus_tag="L3Q65_RS04210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04210"
                     /product="response regulator"
                     /protein_id="WP_182896102.1"
                     /transl_table=11
                     /translation="MSVRVLLVDDERLIRAGLRAIVDSEPDLTVVGEASDGSEVPGLVG
                     RLRPDVVLMDVRMPAVDGIRATGHLLSTVEDPPKVIVVTTFENDDYVYDALLAGASGFL
                     LKRARPEEIVAGIRTVLAGDSLLFPAAIRGMAARRAPGAAAPLDFLTERERDVLRLMAA
                     GLSNGEIAAELFLGLQTVKTHVGNVLSKLGARDRTQAVIRAYESGFVRPTG"
     gene            complement(8176..9855)
                     /locus_tag="L3Q65_RS04215"
                     /old_locus_tag="L3Q65_04215"
     CDS             complement(8176..9855)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020658188.1"
                     /locus_tag="L3Q65_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04215"
                     /product="GGDEF domain-containing protein"
                     /protein_id="WP_237598815.1"
                     /transl_table=11
                     /translation="MTTLRAVRFAFQPMYSLHTGGVVAYEALARPGRGTAHELLAEARR
                     EGRLTEVDLGLAAAAVRQEAERPSALPLHLNVSARTLASPLEAFDELIAELGAAGRRTR
                     DVVLEVGPPFTHLPTGRLLDGMRALTEQGFRLALDGLGRGDLPLALLAQSPVDLVKLDR
                     SVLRGLPGDPAATAVVEALLHYTTRTNIRLVATGIETESQLDAAQSLGVRIAQGNLLAP
                     PAAHRSAPASGAVIPEDRRTPAPPQAPRVGDFLRPATTLPVDATCDDVREVLAAADAPS
                     GVVGVDADNRPQWSVDRTRFLVTITGPYGHALHAKRSAARLADKPRLIEAGASALEFLE
                     LVTDADWGRTGDDVVVVDASGRCLGVVLVTEVVRGVAEAKVEEAVTLSPLTRLPGSEAA
                     ARDVERRIASGEQFVAAWLDVDAFKSVNDNAGFAAGDDLIRALGETLTDLSRRLPRMRV
                     SHVGGDDFLIVCDVDEIGTVAAALLDTHWSAEGMPVTVSLATLVCGSGTIPSYRDASRL
                     LAPLKKRAKAVPGSSWVLSRPGSDRVEVLRGIGRDVAISRSA"
     misc_feature    complement(9889..9900)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     misc_feature    complement(9944..9953)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.36"
                     /tool="antismash"
     gene            complement(10001..11107)
                     /locus_tag="L3Q65_RS04220"
                     /old_locus_tag="L3Q65_04220"
     CDS             complement(10001..11107)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075927.1"
                     /locus_tag="L3Q65_RS04220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04220"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_237598816.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 1.8e-53, bitscore:
                     181.1, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVLVAGGGPAGRALAAACARRGLETAVLDPDPHRKWPNTYGMW
                     ADEAPELPGEAIAAAPAATLAFGTREHRVDRAYRVIDNAGLREWLTEPSVQVVTGKVTG
                     AEHGPHGTTVLLADGRRLAAAVFVDASGAPKLRAPRAEQTAYGLVLPADQAERLAPPDT
                     AVFMDWRDGTDSFRYALPLGDGSVLVEETSLARKPGLPVAELAQRLHARLKAAGIRPAG
                     RVEQVRIVLDVPLPKRGQSVPFGVAGALVHPATGYSLATALQLAPRVAQALADAFDAGP
                     AAAASAARKALWPPEARAVHALRRHGLRALCGMSPAQSAQFFDLFFDLPIPAQRAFTSG
                     RTDLPGTASTMANLFRAAPARLRRLLLG"
     gene            11146..12708
                     /locus_tag="L3Q65_RS04225"
                     /old_locus_tag="L3Q65_04225"
     CDS             11146..12708
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637142.1"
                     /locus_tag="L3Q65_RS04225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04225"
                     /product="deoxyguanosinetriphosphate triphosphohydrolase
                     family protein"
                     /protein_id="WP_182896099.1"
                     /transl_table=11
                     /translation="MDETDPRAARRDPANGAGGFTDLATSPFRVDRDRITASPFFARLG
                     GVTQVVSAGGAGLLHNRLTHSLKVAQVARGIAERITGSSESAELAAKLGGCDPDACEAA
                     ALAHDLGHPPFGHLGEQTLDRIARHRFGLADGFEGNAQSFRILTTTDVRGPSAIGLDLT
                     TAVRAAVLKYPWARLHYPQPHPTAMPLPPRGAAEPDDAPGTGASKFSAYVTELDDFEQS
                     RAPFAGRIEPWQQTVEASVMDTADDIAYAIHDLQDFHRIGVLQHAPVAAELGEWLAHAV
                     DLASLDDARLTAEIRRPGRSLERMRRRMHLKDSWIVDDDAFAAAVARVQRELVDGLLAD
                     GFDGSTEAEQATAAFSANWMARLVDGVFVLSSPPTRSGHVSLRPAQWHEVQVLKFVHRR
                     FVLLRPDLALHQRGQASLVTTLVDALDAWLLDRDEASRLPRRLHDLMELAHGEYSDLAR
                     TAPELLVGATGERIEGADAVRGLARGRAVVDFVASLTDKQAVTLLDALSGRSSQPWSDS
                     FVL"
     gene            12749..13240
                     /locus_tag="L3Q65_RS04230"
                     /old_locus_tag="L3Q65_04230"
     CDS             12749..13240
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075932.1"
                     /locus_tag="L3Q65_RS04230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04230"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_220508564.1"
                     /transl_table=11
                     /translation="MPVTIREAGADDWPGIWPIVRDVVTEQRTFPYDPAMSESEARRQW
                     LVPAPARVVVAAEGDRVLGTANMYANRPGPGSHVASGSLMVSRDARGSGVGRALVLDLI
                     AWARRAGFAAIQFNAVVETNVHAIRLYESLGFVTLGVAPGAFRHPVEGRVGLRIMWLEL
                     "
     gene            13237..13770
                     /locus_tag="L3Q65_RS04235"
                     /old_locus_tag="L3Q65_04235"
     CDS             13237..13770
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L3Q65_RS04235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="L3Q65_04235"
                     /product="hypothetical protein"
                     /protein_id="WP_237598817.1"
                     /transl_table=11
                     /translation="MTRFAEVFTLGARLPGQVFREPRGDSLFCEYDVVLAPEIWPALRE
                     MARWHGDDRVDLLVLEPGARQTVSAPVGSEGYWSAIGHESDDEFLDSIAVTADVIAVTG
                     PSGKWGCWGERGPEVAVFQGFPDAAAREEWRERFGPFLDAAEAVESYVWMAFGGRRPVP
                     DEYAAALVADYGIG"
     misc_feature    13793..13807
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            13806..14516
                     /locus_tag="L3Q65_RS04240"
                     /old_locus_tag="L3Q65_04240"
     CDS             13806..14516
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013500.4"
                     /locus_tag="L3Q65_RS04240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04240"
                     /product="barstar family protein"
                     /protein_id="WP_237601041.1"
                     /transl_table=11
                     /translation="MYRVVSEESRPGFALPFEPLHGFFADEETAGKVTFAGIIGAADAR
                     PVTVDDAELEVLDDSGDAIGRYWLGRFELKPKNISPAPGGSASLEVPSCGGEPCPHEQA
                     IWSRWRRGSILLGEWTRHPATQHGNWLHVVQNAWFTSGKHAMRCDTGDIVIDGQHWSSK
                     DSFSCAIGEAANGPGGCFGSNLAALHDCVRSGSKAAQRYSVSWNAVETSRRALGDAFVT
                     AVTEIFGQYNVEPR"
     misc_feature    14010..14012
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14786..17590
                     /locus_tag="L3Q65_RS04245"
                     /old_locus_tag="L3Q65_04245"
     CDS             14786..17590
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005152179.1"
                     /locus_tag="L3Q65_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04245"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_237598818.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2e-15, bitscore:
                     55.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAAAVLAAGLATPPLAEAQESTVDSTANSQIAALQAVKAGQTAT
                     ESKIDSKLLVQEKMRTRSLSAAALPGIARIADKALVDIRVTKVSDGLVNDLRKAGAEVR
                     AMSSTAASIRAEVPLTALPEIAKRGDVKHVETADQAMTARQRENKEGSETKQQKADRID
                     RQLKEAIGTKTQVVSAGDRAHNADTARQQFGVTGTGVKACALSDGVDSLEVSRTKGELP
                     AVDVLTGQAGSGDEGTAMLEIIHDLAPNAKLGFATAFTSDASFADNIRKLRFEAHCDVI
                     VDDVIYFKESPFQDWIIAQAVNDVTADGALYFSSAGNEGNVADGTAAHWEGDFADSGIS
                     IGKYAGTAHNFAGAAGKQAFEPISDASSANIPVTLHWSDPIGAAADDYDLYLLDARGNV
                     VSFSQDVQNGTQDPYEQLATPFFGGTGLRLAVVKFSGASRYLSLTAFGSRFRDSADGLK
                     AYSTPGAVVGHAAARKAFAVAAAPAEAAFGRPLEPGDPANPTGPYPAAYSATSKAERFS
                     SDGPRRVFYEANGTPITPGDVSSTGGEVRQKPEITAADGVHTSVSGFDPFFGTSAAAPH
                     AAAIASLVLSGNPGLSSSDIREAFLKTAVDIEAPGTDNLTGAGVLLADKVLAYTGASPQ
                     PYAEAGQPTVRGPNGGSTLNPGDIATVTLPVKNTGDGTAVSTSVVLTSPTPGVAIEPRA
                     KSYGTISPGQTGINDFTVTVPAGQQLGSPVVLNAKVTFAGSFSPRTSTFSLPVGTPSPV
                     SQAFAYAGPAVAIPDNSPLGASVPLVVSGVGPASKVSLSIDGTACTTAEKATTVGIDHT
                     YVNDLVGTLTAPSGATATLFQKGGGSGNNLCQVVFDDSATKLFSTTGSADAPYTGTYRP
                     VTPQSQPGASADGTWTFKVVDTTGGDTGSIRSVSLHVNGYATAGRPADVHKTVTAGPVR
                     PQLA"
     gene            17638..18315
                     /locus_tag="L3Q65_RS04250"
                     /old_locus_tag="L3Q65_04250"
     CDS             17638..18315
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016699278.1"
                     /locus_tag="L3Q65_RS04250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04250"
                     /product="acVLRF1 family peptidyl-tRNA hydrolase"
                     /protein_id="WP_237598819.1"
                     /transl_table=11
                     /translation="MARQVAGGGRAVEVPPERLDGWFARFAERNGGVRATVLSATQVRV
                     TAGNGTTATATVPFGPLKEQGEYPGLAVGPLLHHVRTPRLIALLLVRKGGHSLGLAYDG
                     RVVLSRTDRHHVQGRTAAGGWSQQRFARRREGQTRAALQSAAQDAYEVLLPRLSEVDAV
                     VLGGDRRALDELRSDRRLAELFDRAEPRVLDLPEPRHEVLADAAQRARAVELVVRDRTA
                     GRE"
     gene            <18474..>19061
                     /locus_tag="L3Q65_RS47545"
                     /pseudo=""
     CDS             18474..>19061
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="L3Q65_RS47545"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVLLITATGLELRAGSRILLNGATLRIQSGDRIGLVGRNGAGKTT
                     SLKVLAGEGEPHAGDVRRSGELGYLPQDPREGDLSVTAKDRVLSARGLDTLLRDMEKAQ
                     TSMSELVDDKQRDKAINRYARLEERFSSLGGYAAESEAARICSNLGLADRILSQTLSTL
                     SGGQRRRVELARILFAAAEAGAGGKSETILLLD"
     misc_feature    complement(19176..19191)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            19185..20111
                     /locus_tag="L3Q65_RS47550"
     CDS             19185..20111
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="L3Q65_RS47550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_370648251.1"
                     /transl_table=11
                     /translation="MWFLDATRGEIDIYNMSWQRYLDARATDEKRRRRERANAEKKASA
                     LQAQAAKLGAKATKAVAAKNMARRAEQMLSSLDETRQADKVARIKFPEPASCGRTPLTA
                     DGLSKSYGSLEIFTGVDLAIDRGSKVVVLGLNGAGKTTLLRLLGGMETPDTGSVEPGHG
                     LRLGYYAQEHETLDHEASVWENIRHLAPDTGAQELRNLLGSFLFTGEQLDQPAGTLSGG
                     EKTRLALAGLVSSQANVLLLDEPTNNLDPASRAQVLDALRSFAGAVVLVTHDPGAVEAL
                     EPERVILLPDGTEDHWSADYLELVQLA"
     misc_feature    complement(20285..20299)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            20291..20500
                     /locus_tag="L3Q65_RS04260"
                     /old_locus_tag="L3Q65_04260"
     CDS             20291..20500
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003071237.1"
                     /locus_tag="L3Q65_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_04260"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_003071237.1"
                     /transl_table=11
                     /translation="MADLKKGARITGNTRDKLAADLKKKYEKGSSIRALAESTGRSYGF
                     VHRVLSESGVQLRGRGGATRVKKK"
ORIGIN
        1 actacctgtc cgccatcggg atggaccgcg tcgcggcgca cgagcacgaa ctggccgcgg
       61 cggcgatcgc gggcatcagc gcgatcccgg gcgtgcgcat cgtcgggccg accgacctcg
      121 aagaccgggg cgcgaccgtc gcgttcgtga tcgacggcgt gcacccgcac gacgccggcc
      181 aggtgctcga cagcctcggc atcgcggtgc gggtgggaca ccactgcgcg tggccgctgc
      241 accgggcctg ttcggtgccc gcgaccgtgc gggcgagctt ctacctgtac aacacgctgt
      301 ccgaagtgga cgctctggtc gccgggatcc gcgaggcgca gaagttcttc ggggtggacc
      361 agtgaacctg gagagcatgt accaggagat catcctggac cactacaaga acccgcacgg
      421 gcgcggcctg cgcgatccgt tcgacgcgga gtcgttccag gtcaacccga cctgcggcga
      481 cgagatcacc ttgcgggtca aggtcagcga cggcaaagtc gaggacgtgt cctacgacgg
      541 gcagggctgc tcgatcagcc aggcgtccgc gtcggtgctg accgacctgg tcgtcgggca
      601 caccgtcgac gaggcgttca cgaccatgga cgccttcgtg gaactgatgc agggcaaggg
      661 caaggtcgaa ccggacgagg acgtactgga ggacggcgtc gcgttcgccg gcgtcgcgaa
      721 gtacccggcg cgcgtgaagt gcgccctgct cggctggatg gcgttcaagg acgcggtgtc
      781 cagcaccacc acaggagctg agaaggcatg agcgcagctt gcaagcgaat catggttgtt
      841 catgccgtcg cctcccaggc aatgagcgtg aaactcctta aggaggcgac ggcatgagcg
      901 aagagacggc caccgacccg cgcgaggggc gcaccgccgc ggacctgccc gagcagtccg
      961 ccgccgtccc cgccgacatc gccaagatcg aggacgtcga ggaagcgatg cgcgacgtcg
     1021 tcgacccgga actcggcatc aacgtcgtgg acctcggcct ggtctacgac atccgggtcg
     1081 agaccgacaa caccgcgacg atcgacatga cgctcacgtc cgcggcctgc ccgctcaccg
     1141 acgtgatcga agaccagacg tcggcggcgc tgacgtccgg cggcctcgtg aacgacttcc
     1201 ggatcaactg ggtctggatg ccgccgtggg gcccggagaa gatcaccgac gacggccgcg
     1261 agcagttgcg ggcgctcggt ttcacggtct gaggcttttc gaaggccgct cccggtatcg
     1321 ccgggggcgg ccttcggcgt atcccggatt ggtgcgttcg ggcgcatgcg ggcggaacgc
     1381 cggtttctgt cggtcccggg tgctatgact ggtcgatgac cgaacctgat tccgcatccg
     1441 tgtcctctcc cggggacaga cccgggcgcg gcctggccgt cgcggcggtg tccgtggccg
     1501 cggtgagttt cgcgctcggg gtggcgacct ggctcgcctg gctcctcgtg cgcccgaggc
     1561 tgctcatggg cggcatctac ccgatcgtgg ccgaggtgtt cgtcctggtg ctgggcgcgc
     1621 tgtggttcct ggcggtgctg gcctcggtgc tggccgtggt cttcggcctg ctcgcgggag
     1681 cgcggcgcta cggcgccgat ctcgccaggc tgggcgcact gctgggcggg ctggcgttcg
     1741 tggtggcgct ggccgggact gtcgcgttca cgtcgaatcc cgggttcacg accggacagt
     1801 tcgatgtccg gcctacgcat gcgacgctgg ggcggtgaag tctgtataac gacctatacg
     1861 gcggcgcgga gccgtgcgag tccattgtgg acggaatggc ccgatccgcc tgggcgatgc
     1921 ctggctgggc agggagagct gtcgatcctc gtgcggtgat ggatggtttc tcggccccgc
     1981 tgtcaggttt ccgcttggct cgcgaccggg ggcgcacgcc gccccggcga cggcgtccgc
     2041 ggccgtgaga ttgccgagtg cgccagaggg gacctaggcg ggagctctcc ggcgcaggct
     2101 gatgccctgc gagcctgcca ggtaacgact gtccgaatcc atccgatgat cgcttcgtga
     2161 cagaaggctt ccctgccgct ccgcctccgg ccgggcgtgc gccgcgccgg ttttcctggg
     2221 tgctcgctgc tttcgtcgtg gtcgcgctcg cgggctcggt cgtggcggtg accgggctcc
     2281 tcaaggtgtt cagttaccgg tcgctgaccg tgacgggcgg gtcgatggcg aataccgtcg
     2341 tgtcgggcga gcgggtcgtc ttcggactgc gcgagggcca ggagatccac cgcggcgacc
     2401 ttgtcgtgtt cgacgcgagc gcgttcggcg acggacggcg cgggacgttc ctgcagcgcg
     2461 tgatcgcggt cggcggcgac gaggtcgaat gctgcgacct ggagcgccgg atcaaggtga
     2521 accgcaagtc gatcgacgag ccttacgtgg ccggcgagca gacgcccttc tacgcgaaag
     2581 tgccgacggg cgcggttttc ctggcggggg accggcggga catcgcggac gactcccggt
     2641 ggcgggtcaa cgaacccggc ggcggagcgg tgtcgttgtc cgcggtgcac ggcgtcgtct
     2701 cggcgaccgg gaatctgttc tgggtcaggc agatcccggc gacgaccgcg ttcaccgccg
     2761 ccgggtttcc cgggacgacg gagccggatt ccggaccggt caccggccgg atcaccgccg
     2821 gagccggggc ggggctgttc ctcatcgggt tcgccggtct gctcgggacc gtcgtccgga
     2881 gcgccggaag acgacgaaaa gcagccgcag tcccgccagc gcgctgatca tcagcaggtt
     2941 gtagccgaac acgtggttca gggtcagccc gggcaccacc tgcggaccgc tggaactgcc
     3001 cagcagcagc acggccatga gcccggtcgc gatgccgacc agcgccagca gcacctcgtg
     3061 caccaggccg gtcaccaggt cgcggtcgcg ttcgtcggag aacagccgca tgttcaccga
     3121 caagcggcct tcctccagtg ccgcgccgat ccggtcgacc cggcggggga ggcggcgcag
     3181 gaccggaagc agcgcggtga attcgtcggt gacggtgcgg cgcagggttt ccgggcgcag
     3241 gccgatgcgt tcggtggcga acgcgcggga ttcggcgacc aggtcgaagt tcggcgcgag
     3301 cgtcgcgagc gtgccttcca tggtcgccaa cgcgcggaac accgcggcga tcggcggcgg
     3361 gacggccagg cggaagtcgg cgacgactcg gaacaggccg gtgaacaggt cgagaccggg
     3421 cgttcggccg gggccgaagt gccgggccag cagggcgccg agcgcgcgtt ccaggcgttg
     3481 ttcgtcgagg tcgtcggggc ggttgacgat ttccagcaac ccgtcgcgca cgccggcggg
     3541 gtcgccgcgg tcgatggctg gcagcagggc ttgcaggccg gcgcgcaggc cggtgtcgag
     3601 gcggcccacg gagccgaagt cgagcaggcc gagggtgccg tcttcgagca gcagaacgtt
     3661 gcccgggtgc ggatccgcgt ggaacacgcc gcccagcagc acctggtcga gcaggccgcg
     3721 caggaaggtg cgggcgagtt cctcgcggga gcatgcggaa ccggcggaaa gcggtttgcc
     3781 gtccagccgg cgcatcacca ggacacgttc cgtggacagt actttgtgga cagccggaag
     3841 ggtgacgccg gggaccggat gcgcggcgat cgcctcgatg ttcgcggctt cggtgcggaa
     3901 atcgagttcg tcctcaaggg attcggcgaa gccgtcggcc agttcccgca cgccgagcga
     3961 acgtgcccag ccggcgcgta cgtacagcac gtcggcgagg cggcggacga tgtcgatgtc
     4021 gcgttccact tgctcgcgga tcccgggccg ctgcaccttc acgaccacct cggcgccgga
     4081 ccgcagccgg gccccgtaaa cctgcgcgat cgacgctgcg gcaaggggtt cgtcgtcgat
     4141 gtgggcgaag gcagtcacgt cgatttcctc ccgcagcaac gcgcgcacct cgtcttcggg
     4201 tgcgggcggg acctgatcgt gcagcttgct gagttcgcgg atgtacaccg gcggcaggag
     4261 atcggcgcgc gtcgaaagca gttggccgag cttcacgaac gtcacgcccg cttcttcaag
     4321 cgccagtcgt agcgatcgag cgagtttcgc cgagccgtcg gggcccgcgg tgcgccggcc
     4381 ggtgaggaac gagccgagac cgtggcggat cgcgatgcgc atgatgcgcg agtagcgacg
     4441 ggcgcgggcg gcgcgggagc gcagcgaccg catccgggcg aacaggcccg gcccgccgga
     4501 cggaaccgcg agttcggcga cgaaaaggac cagcagggtc accgcgagcg cgctgcccgc
     4561 cagcgggatc agcagtccga tcgcgacccc ggcgttggac agcacggcga tcgggaacaa
     4621 ccggatgacg gtgcccgcga cgagccagcc cgcgagcgcg gcgccgagcg cccggacgag
     4681 accgacgcgc acaccgagca ccttgcgggc cgcggcgacg agcggccaca gcacgacgac
     4741 gtaggccagc aggccgagca gcagcgtttg catgccgacg agcacaccag cccggcggcg
     4801 cccgcggatc cagccggggc gggacgggcc tccctctcgc gggggagcgt cctactttcg
     4861 gacgtagtcg cccgcggcgg tgaacttcta acgtcatcca gcggataaag ggttgcttgc
     4921 tttcccgatg acgtacggag gacacgatgc acgcacgagg gttccggcgg atcgccgcac
     4981 tggccgcggc gaccgccgct ccgctgggct tcggcctggc gaccgcaccc gccgcgtccg
     5041 ccgccgcggc gaccaccgtc tactacagct cggcgggcgc gccggactac gtcgcccaga
     5101 tcgaccaggg cgcggccaac tggaacgccg cggtcagcga cgtgcggctg gtcaaggacg
     5161 agggcaaggc cacggtgaag atccacgagg tcaacagcgg cgggtcgtac acgcagaccg
     5221 acgggcacgg caacggagac gtctacctgg acacgagcca ggtcgccgag ggctacgacc
     5281 cgacccgcat cgccgcgcac gaactcggcc acaacctcgg gctgccggac cactacgagg
     5341 ggccgtgcac ggagctgatg tcgggccacg ggccgggcac ctcgtgcacc aacgccaagc
     5401 cggacgcgca ggaatcggcg aaggtgcagc agttgtgggc caacgggttc cggatcgacg
     5461 gcacgcgggt caccaagacc gtctactgag ggcctcgtga gtggcgatca cggttctaac
     5521 cgggattgcc actcacgacc tcctactccg cctgcagcag gaagaacaag aagctcgggc
     5581 tgacgcacag catccggtag tcctccggga acagcttttc cgcctccggc accggtttcg
     5641 gctcgctgat cgtcgagatc cggaacccgg cctcggcgaa cgcgtcggtc atcgcgtgca
     5701 gcgggcggtt ccagaagctc atcggcgtcg tccggccgcc gacctcccag tcctcggtcc
     5761 attcgtaagt cgccgagtag tccgtctgct gcccggcctg gcgttgcagc aggtggatcg
     5821 cgtacggatg gtcgaccacc acgatcagcc gtccgccggg ccggaggaca cggtggaatt
     5881 cggtgagcgt cgggccccag tccttcaggt agtgcagcac gagcgaggcg atgacgtcat
     5941 cgaaagcgtt gtcggcgtag gggagtggcc cggcgacgtc ggcgacgcgc aggtccacgt
     6001 ccgggcctag ccgctggcgg gcgatctcga gcatgccgct gctcaggtcg aagccggata
     6061 cctcggcgcc gcgttcgcgc agtgcgacgg tcagcggtcc ggcgccgcag cccgcgtcga
     6121 gaatccgccg tccggccacg tctccggcca gcgccagcac ggcgggccgc tcgtagtagg
     6181 cgttctggat ctccgtgtcc gacatggcgg tgtaggtctc ggccagcagg tcgtaatcgt
     6241 tgatcacggt gctctcttcc gaaggcatgc gatccaggct gccagaaaac cgccgccagg
     6301 gtcccgccct ggagggaggc gtccgccggg accgcctgtc aggattggcg ggtgcgtttc
     6361 cttcgtccgc tggtcagcgg ggtcacctat cgccgatggg tgtacctgat cctcggcgcc
     6421 gcgctcagcg tgccgtacct gctgctcgcg atgatcgcga tgccgtcgct gatgccgttc
     6481 gcgacgacga tgggatgggc gagcgtcgcc ggattcgtcg tgatgctcgt cgtgctggcc
     6541 gcgaccgcgt tcctgccggc ggtgcgggtg ctggaggcgg cggcggtgcg ggaactgctc
     6601 gcccagcccg cgccgggacg cggacggctg cggtgcgcga cgatgttcgt gctgcacgtc
     6661 gtggccggtt tgttcaccgg gctcgcgacg ctcgccctgc ccgccggatt cgggttcgcg
     6721 atcaacgcgg tcttcaccgg tcggcttgtc gacactccgg atttccatct gacggttccg
     6781 cgcggctggg cttcggcgtg gctgcccgcg gcgttcgtgg cggctttcgt cgtgctgatc
     6841 tacttcgtgt gggccctcgg cggagtgctg cgccgcgcgg cggcccggtt gctcggctgg
     6901 tccgccgccg aacgcatcgc acagctcgaa cgccgcaccg accagctcgc cgaacgcacc
     6961 cggctcgcgc gcgaactgca cgattccgtc gggcacgcgc tttcggtggt cacgctgcaa
     7021 gccggggccg cacggcggac gctgcacacc gaccccggct tcaccgagga agcgctcacc
     7081 gcgatcgagg aatcggctcg caccgcgctc gacgacctcg accacgtgct cggcctgctc
     7141 cgcgacgaag cacgcgaccg gacgccgcac gcgggtctcg ccaacctgcc cgcgctgatc
     7201 accgtgacgc agcagtccgg gacggagtgc cgcgtcgagg tgcaaggcga tgtcggcgcg
     7261 gtgccggcgg tggtttcccg cgaggtgtac cggattttgc aggaatgcct cacgaacgcg
     7321 gtgcggtacg cgggcaaggt gccggtcacc gtcgcgctgg cggtcgcgga cgggcagttg
     7381 cgggccgcgg tcgcgaaccc gctcggttcg gcccgtccgt cgcgcgtccg cggcggacgc
     7441 ggtctgcggg gcatggcgga gcgggcggag ctggtgggtg gcaagctgtc cgcgggaccg
     7501 gtgggcgaga actgggaggt cgtggtgacg gtgccgtggg ggaaccggtg agcgtgcgag
     7561 tcctgctggt ggacgacgaa cggctgatcc gggcggggct gcgggcgatc gtggacagcg
     7621 aaccggatct gaccgtggtc ggcgaggcgt ccgacggctc ggaggtgccg ggtctcgtcg
     7681 gccggctgcg gccggacgtc gtgctgatgg acgtgcggat gcccgcggtg gacgggatcc
     7741 gcgcgaccgg gcatcttctg tccactgtgg aggatccgcc gaaggtgatc gtggtgacca
     7801 ccttcgaaaa cgacgactac gtgtacgacg cgctgctcgc cggcgcgagc ggattcctgc
     7861 tgaaacgcgc gcgtccggag gagatcgtcg ccgggatccg cacggtgctg gcgggggatt
     7921 cgctgctgtt cccggccgcg atccggggca tggccgcccg ccgcgcgccg ggtgccgccg
     7981 cgccgctgga cttcctgacc gaacgggaac gagacgtact gcggctgatg gcggcgggac
     8041 tgtccaacgg ggagatcgcg gcggagctgt tcctggggct gcagacggtg aaaacgcacg
     8101 tcgggaacgt gctgtcgaag ctcggtgcgc gggaccggac gcaggcggtg atccgggctt
     8161 acgagtcggg cttcgtcagg ccgaccggct gatggcgacg tccctgccga tgccgcgcag
     8221 gacctcgacg cggtcgctgc cggggcggct gaggacccag ctggagccgg gaacggcctt
     8281 ggcgcgtttc ttgagcggcg cgagcagccg ggaagcgtcc cgataggacg gaatcgtgcc
     8341 gctgccgcac acgagcgtcg ccagggaaac cgtgaccggc atgccctcgg cggaccagtg
     8401 cgtgtccagc aaagccgcgg cgacggtgcc gatctcgtcc acgtcgcaca cgatcaggaa
     8461 gtcgtcgccg ccgacgtggc tcacgcgcat ccgcggcagc cgccgggaaa ggtcggtgag
     8521 ggtttcgccc aaggcgcgga tcagatcgtc tcccgcggcg aaaccggcgt tgtcgttgac
     8581 cgacttgaac gcgtcgacgt ccagccacgc cgccacgaac tgctcgccgc tcgcgatccg
     8641 gcgttcgacg tcgcgcgccg ccgcttcgct gcccggcagc cgggtgagcg ggctgagcgt
     8701 gaccgcctct tcgaccttcg cctcggcgac cccgcgcacg acctcggtca ccagcacgac
     8761 gccgagacag cgcccggacg cgtcgaccac cacgacgtcg tcgccggtgc ggccccagtc
     8821 ggcgtcggtg accagttcga ggaattccag tgcgctcgcg ccggcctcga tcaggcgcgg
     8881 tttgtccgcc agccgcgcgg cggaccgctt cgcgtgcagg gcatgtccgt acggaccggt
     8941 gatggtgacg aggaatcgcg tccggtcgac tgaccattgt ggacggttgt ccgcgtcgac
     9001 gccgaccacg ccgctcggcg cgtccgcggc ggcgaggacc tcgcggacgt cgtcgcaggt
     9061 ggcgtcgacc ggcaaggtgg tggccgggcg caggaaatcg ccgacgcgcg gggcctgcgg
     9121 cggcgcgggc gtgcgccggt cctccgggat gaccgcgccg gaggcgggcg cggaccggtg
     9181 cgcggcgggc ggtgcgagca gattgccctg cgcgatccgg acgccgaggc tctgcgccgc
     9241 gtccagctgc gactcggtct cgatcccggt cgcgaccagc cggatgttcg tgcgcgtcgt
     9301 gtagtgcagc agcgcctcga ccaccgccgt cgccgccggg tcaccgggaa ggccgcgcag
     9361 cacgctgcgg tcgagtttca ccaggtccac cggggactgc gcgagcagcg ccagcggcag
     9421 gtcgccgcgg ccgagcccgt cgagcgcgag ccggaagccc tgttcggtga gcgcgcgcat
     9481 gccgtcgagc aggcggccgg tgggcaggtg cgtgaacggc ggcccgacct ccagcaccac
     9541 gtcgcgggtg cgccgtccgg ccgcgccgag ttcggcgatc agttcgtcga acgcctccag
     9601 cggcgacgcg agcgtgcgcg cggagacgtt gaggtgcagc ggaagcgcgc tgggccgctc
     9661 ggcctcctgg cgtaccgccg cggcggccag cccgaggtcg acctcggtga gcctgccctc
     9721 gcggcgggcc tcggcgagca gttcgtgcgc cgtgccccgg cccggccggg ccagcgcttc
     9781 gtacgcgacg accccgccgg tgtgcaagct gtacatcggc tggaaggcga atcggaccgc
     9841 acgcagcgtc gtcacggacg cgatactcgc accgccggag ggggctgcga aaccgttgtc
     9901 agctgatgtt caccagcgcg gcactttggc caccggaacg gagtaacaaa atgcttttcg
     9961 cgttcgctcg atcgggcaag gcaaaattcc cggcacgggc tcagcccagc agcaggcggc
    10021 ggaggcgggc cggggcggcg cggaacaggt ttgccatggt cgaggcggtg ccgggcaggt
    10081 cggtgcggcc cgaggtgaac gcgcgctgcg ccgggatcgg aaggtcgaag aacaggtcga
    10141 aaaattgcgc tgactgagcg ggtgacattc cgcacaatgc acggagtccg tggcggcgca
    10201 aggcatgcac agcacgggct tcgggcggcc acaatgcctt ccgggcagca ctggccgcgg
    10261 ccgccggacc tgcgtcgaac gcgtccgcga gagcctgcgc gacgcgaggc gcgagctgca
    10321 gcgcggtcgc gaggctgtag ccggtcgccg ggtggacgag cgcgcccgca accccgaacg
    10381 gcaccgactg gccgcgcttc ggcagcggga cgtcgagcac gatccgcacc tgttcgaccc
    10441 ggcctgcggg acggattccc gccgctttga gccgggcgtg cagccgctgg gccagttcgg
    10501 ccactgggag cccgggtttg cgcgcgagcg acgtctcttc gaccagtacg gagccgtcgc
    10561 cgaggggcag tgcataccgg aagctgtcgg tgccgtcgcg ccagtccatg aagacagctg
    10621 tgtcgggcgg ggcgagccgc tcagcttggt ccgcgggcag cacgagcccg tacgcggtct
    10681 gctcggcgcg tggagcccgc agcttgggtg ctccggacgc gtcgacgaac actgcggcgg
    10741 cgaggcgtcg accgtcggcg agcaggaccg tcgtaccgtg cggaccgtgt tccgcgccgg
    10801 tcaccttgcc ggtgacgacc tggacgctcg gctcggtgag ccactcgcgc agcccggcgt
    10861 tgtcgattac ccgatacgcc cggtcgacgc ggtgctcgcg ggttccgaac gccagcgtcg
    10921 ccgccggagc cgcggcgatc gcttcgcccg gcagctcagg cgcctcgtcc gcccacattc
    10981 cgtaagtatt cggccacttt cggtgtggat ccgggtcgag cacggccgtt tccaggcctc
    11041 gccgggcgca cgcggccgcc agcgcccgtc cggccgggcc gccgcccgcc accagcacgt
    11101 cggtcatccc gcaatcctgc cggacggccg gatacggtgg gacacatgga cgagaccgat
    11161 ccgagggcag cgcggcggga cccggcgaac ggggcgggcg ggttcaccga cctggcgacc
    11221 agcccgttcc gcgtcgaccg cgaccggatc accgcgtcgc cgttcttcgc gcggctcggc
    11281 ggggtcaccc aggtggtcag cgcgggcggc gccgggctgc tgcacaaccg gctgacgcac
    11341 agcctgaagg tcgcgcaggt cgcgcgcggg atcgcggagc ggatcaccgg atcgagcgag
    11401 tcggccgaac tggccgcgaa actcggcggc tgcgacccgg acgcgtgcga ggcggccgcc
    11461 ctggcgcacg acctcgggca ccctccgttc gggcatctcg gcgagcagac cctggaccgg
    11521 atcgcacggc accggttcgg cctggccgac ggtttcgagg gcaacgcgca gtcgttccgc
    11581 atcctcacga cgacggacgt gcgcggcccg tccgccatcg ggctggacct gacgaccgcg
    11641 gttcgcgccg cggtcctgaa atacccgtgg gcgcggctgc attacccgca gccgcatccg
    11701 accgcgatgc ccctgccgcc ccgcggcgcc gccgagccgg acgacgctcc aggcaccggt
    11761 gcgagcaagt tttccgcgta tgtcacggaa ttggacgact tcgagcagtc gcgggccccg
    11821 ttcgccgggc ggatcgagcc gtggcagcag acggtcgaag cgtccgttat ggacactgcc
    11881 gacgacatcg cgtacgcgat ccacgatctg caggatttcc accgcatcgg cgtcctgcag
    11941 cacgcccccg tcgccgccga actgggggag tggctggcgc acgccgtcga tctggcctct
    12001 ttggacgatg cccggctgac cgcggaaatc cgccgcccag gccgttccct ggagcggatg
    12061 cgccgccgca tgcacctgaa ggacagctgg attgtggacg acgacgcctt cgccgccgcc
    12121 gtcgcccgag tccaacgaga actggtcgac ggcctgctcg cggacggctt cgacggttcg
    12181 accgaggccg aacaagcgac ggcggcgttc tcggcgaact ggatggcgcg attggtggac
    12241 ggggttttcg tcctgtcgtc gccgccgacc cggtccgggc acgtctcgct gcgtcccgcg
    12301 cagtggcacg aggtgcaggt cctgaagttc gtccaccggc ggttcgtgct cctgcgcccc
    12361 gatctcgccc tgcaccagcg cggccaggcc agcctggtca cgacgttggt cgacgcgctg
    12421 gacgcgtggc tcctcgaccg cgacgaggct tcccgcttgc cgcgccggct gcacgacctg
    12481 atggaactgg cgcacggcga atactcggac ctcgcgcgga ccgcgccgga gctgctggtg
    12541 ggcgcgacag gcgagcggat cgagggcgcg gacgcggtgc gcgggctggc ccggggccgg
    12601 gcggtcgtgg acttcgtggc ttcgctgacg gacaagcaag cggtgacgtt gctggacgct
    12661 ttgtcgggcc ggtcgagcca gccctggtcg gattccttcg tgctctaaat cggttgcggg
    12721 acgggtgcct ggtcagcacg gtaggcagat gcctgtgacg atccgggaag ccggcgcgga
    12781 cgattggccg gggatctggc cgatcgtccg ggacgtggtg accgagcagc ggacgttccc
    12841 ctacgacccg gccatgagcg aatccgaagc acgtcggcag tggctggttc ccgcccccgc
    12901 gcgggtcgtc gtcgctgccg aaggagaccg ggtactgggc acggcgaaca tgtacgccaa
    12961 ccggccgggt ccgggcagcc atgtcgcttc gggaagcttg atggtgtccc gggacgcacg
    13021 cggttccggc gtcgggaggg ccttggtgct ggacctgatc gcttgggccc ggcgggctgg
    13081 tttcgcggcg attcagttca atgcggtggt cgagaccaat gtccatgcga tccggctgta
    13141 cgagagtttg gggttcgtga cgctgggggt cgcgccgggg gctttccggc atccggtcga
    13201 ggggcgggtc gggttgcgca tcatgtggct ggaactgtga ctcggttcgc ggaggttttc
    13261 actctcggcg cgaggctgcc ggggcaggtt ttccgggagc cccgcgggga ctcgctgttc
    13321 tgcgagtacg acgtggtgct ggcaccggaa atctggcccg cgcttcgcga gatggcccgc
    13381 tggcacggcg acgaccgggt cgaccttctg gtgctcgaac ccggcgcgcg tcagacggtt
    13441 tcggcgcccg tcggctcgga gggttactgg tcggcgatcg gacacgaatc ggacgacgag
    13501 ttcctggact cgatcgctgt gacggctgat gtcatcgcgg tgacggggcc gtccgggaag
    13561 tggggctgct ggggagaacg cggtcccgag gtggcggtgt tccaaggctt cccggacgcc
    13621 gcggcccgcg aggaatggcg cgagcggttc ggcccgttcc tggacgcggc ggaagcggtg
    13681 gagtcgtatg tgtggatggc attcggcgga cggcggccgg ttccggatga atacgcggct
    13741 gcgttggtgg ccgactacgg gatcgggtga acggtttgct ccggcggggg agatctcagg
    13801 tgccgatgta tcgggtcgtc tccgaggaga gccgtccggg tttcgcgctc cccttcgagc
    13861 cactgcacgg attctttgcc gacgaggaga ccgccggaaa ggtgaccttc gcaggcatca
    13921 tcggcgcagc cgacgcacga ccggtgactg tggacgatgc ggagctcgag gtgctcgatg
    13981 attccggcga cgcgatcggc aggtattggt taggccggtt cgaactgaag ccgaagaaca
    14041 tctccccggc gccgggcggg tcagcgagtc tcgaagttcc gtcgtgcggc ggcgagcctt
    14101 gtccccacga gcaagcgatc tggtcgcgtt ggcgccgcgg ctcgatcctg ctcggcgagt
    14161 ggacgcgaca tcccgcgacc cagcacggca actggctgca cgtcgtgcaa aacgcgtggt
    14221 tcacctcggg gaagcacgcg atgcgctgcg acacaggcga catcgtcatc gacggacagc
    14281 actggtcctc gaaggactcg ttctcttgcg ccatcggcga agcggcgaat ggcccaggcg
    14341 gttgcttcgg cagcaacttg gccgcgctcc acgactgcgt ccgaagcgga tcgaaggcag
    14401 ctcagcgcta ttcagtgagc tggaacgccg tggagacttc ccgccgagcc ctcggagatg
    14461 ccttcgtgac cgcggtcacg gaaatcttcg gccagtacaa cgtcgaaccg cgctgaccgg
    14521 cgactccggc tcccggccgt gcgcgcgaaa gacggcaagc tccgccgaac ggcctacgac
    14581 gtccggctgg caacggatat tgcctgacca acgtcacccc aacggccgtt tttcccggac
    14641 agaagtggta cttagctgga tccagccggt gatcaccggc gttggccagc gtgagtcggg
    14701 gcacgcggtg tgagatcgga ggacgcacgt gcgtcgtacc cgttcacctg gagcctcgac
    14761 aacaaccgcg agaagacgga cgggcgtggt cgccgcggcg gtgcttgccg ccgggctggc
    14821 gacaccgccc ctagcggaag cgcaggagtc cactgtggac tccacggcga acagtcagat
    14881 cgccgctttg caggcggtga aagcaggaca gaccgcgact gagtccaaaa tagacagcaa
    14941 gctgctcgtc caggagaaga tgcgcacgcg gagcctgagc gcggccgcgt tgccgggaat
    15001 cgccaggatc gcggacaaag cactcgtcga catccgggtc acgaaggtca gcgacgggct
    15061 cgtcaacgac ctgcgcaagg ccggagccga ggtgcgtgcg atgtcgagca cggcggcgag
    15121 catccgggcc gaggtgccgt tgaccgcatt gccggagatc gcgaaacgcg gcgacgtgaa
    15181 gcacgtcgaa accgcggatc aggcgatgac ggcgcggcag cgggaaaaca aagaaggctc
    15241 ggaaaccaag cagcagaagg ccgaccggat cgaccggcag ctcaaggaag cgatcggaac
    15301 caaaacgcag gtggtcagcg cgggcgaccg ggcgcacaac gcggacaccg cgcgccagca
    15361 gttcggcgtg accggcaccg gcgtgaaggc gtgcgcgctg tccgacggcg tcgattccct
    15421 ggaggtttcc cggaccaagg gcgagcttcc ggcggtcgat gtcctgaccg gacaagcggg
    15481 cagcggcgac gagggcaccg cgatgctgga gatcatccac gacctcgccc cgaacgcgaa
    15541 gctcggtttc gccaccgcgt tcacctccga cgcgagtttc gccgacaaca tccgcaagct
    15601 ccgtttcgaa gcgcattgcg acgtcatcgt cgacgacgtc atctacttca aggaatcccc
    15661 gttccaggac tggatcatcg cgcaagcggt gaacgacgtg acggccgacg gcgcgctcta
    15721 cttctcctcc gcgggcaacg agggcaacgt cgccgacggc accgccgcgc attgggaagg
    15781 cgacttcgcc gattcgggaa tctcgatcgg caagtacgcc ggcaccgcgc acaacttcgc
    15841 gggcgcggcc ggaaagcagg cgttcgagcc gatttcggac gcgtcgtcgg cgaacatccc
    15901 ggtgacgctg cactggtccg acccgatcgg cgcggccgcg gacgactacg acctctacct
    15961 cctcgacgcg cgcggcaacg tcgtgagctt cagccaggac gtccagaacg gcactcagga
    16021 cccgtacgag cagctggcca ccccgttctt cggcggcacc gggctgcggc tcgccgtggt
    16081 gaagttctcc ggggcgagcc ggtacctctc gctgaccgcg ttcggcagcc ggttccgcga
    16141 ttccgcggac gggctcaagg cgtactccac gcccggcgcg gtcgtgggcc acgccgcggc
    16201 gcgcaaggcg ttcgcggtcg ccgcggctcc ggccgaggcg gcgttcggcc gtccgctcga
    16261 accgggcgac ccggcgaacc cgaccggacc gtatccggcg gcgtattcgg cgaccagcaa
    16321 ggcggaacgg ttcagttcgg acggtccgcg gcgggtgttc tacgaagcca acggaacgcc
    16381 gatcactccg ggcgacgtgt cgtcgaccgg gggagaggtc cggcagaagc cggaaatcac
    16441 cgcggcggac ggcgtgcaca cctcggtgag cggattcgac ccgttcttcg gcacttcggc
    16501 ggccgcgccg cacgcggccg cgatcgcgag cctggtgctg tccggcaatc ccggactgtc
    16561 ctcttcggac attcgcgagg cgttcctcaa gaccgcggtg gacatcgaag ctcccggcac
    16621 ggacaacctc accggtgccg gagtgttgct ggcggacaag gtgctcgcgt acaccggtgc
    16681 cagcccgcag ccgtacgcgg aagcgggaca gccgacggtc cgcggaccca acggcggcag
    16741 cacgctcaac cctggtgaca tcgcgacggt cacgctgccg gtgaagaaca ccggcgacgg
    16801 cacggcggtg tccacgagcg tcgtgctcac ctcgccgacc ccgggcgtcg cgatcgagcc
    16861 gcgggcgaag tcgtacggca cgatcagccc gggacagacc ggaatcaacg acttcaccgt
    16921 cacggttccg gccggccagc agctcggctc gccggtggtg ctcaacgcga aggtgacttt
    16981 cgcgggctcg ttctcgccgc gcacgagcac gttctcgctg ccggtcggca caccgtcgcc
    17041 ggtttcgcag gcgttcgcct acgccggtcc ggcggtcgcg atcccggaca actcgccgct
    17101 cggcgcgtcg gttccgctcg tggtgagcgg cgtcggtccc gcgtcgaagg tgtcgctttc
    17161 gatcgacggc accgcctgca ccaccgcgga gaaagcgacc acggtcggca tcgaccacac
    17221 ctatgtcaac gacctggtcg gcacgctgac cgcgccgtcc ggcgcgacgg cgacgctgtt
    17281 ccagaagggc ggcggcagcg gcaacaacct ctgtcaggtg gtgttcgacg attccgcgac
    17341 caagctgttc agcacgaccg gatccgcgga cgcgccgtac accggcacct accggccggt
    17401 cacgccgcag agccagccag gcgcttcggc ggacggcacc tggacgttca aggtcgtcga
    17461 caccacgggc ggcgacaccg gttcgatccg cagcgtttcg ctgcacgtca acgggtacgc
    17521 gacggccggg cgtccggcgg atgtgcacaa gacggtgacc gcggggccgg tgcggcctca
    17581 gctggcctga gcggtgcggg accgtcgcgc tgcgcggcgg tcccgtaccg tttccccatg
    17641 gcacggcagg tcgcaggcgg cggacgggcg gtggaagtcc cgcccgaacg gctcgacggc
    17701 tggttcgccc gcttcgccga acgcaacggc ggcgtgcgcg ccacggttct ctccgcgacg
    17761 caagtgcgtg tcaccgccgg gaacggcacc acggccaccg cgactgtccc gtttggaccg
    17821 ttgaaggagc aaggcgagta ccccggactg gccgtcgggc cattgctcca ccacgtgcga
    17881 acgccgcggc tgatcgcact gctgctggtc cgaaagggcg ggcactcgct cggcctcgcc
    17941 tacgacggcc gcgtggtcct ctcccgaacc gaccgccatc acgtgcaggg ccggaccgcg
    18001 gcgggcggct ggtcgcagca acgcttcgcg cgccgccgcg aaggccaaac ccgagccgcg
    18061 ctccagtcag ccgcccaaga cgcgtacgag gttctgctgc cccggctgtc cgaagtggac
    18121 gctgtagtgc tcggcggaga ccgtcgtgcg ctggacgaac tgcgctccga ccggcggctc
    18181 gccgagctgt tcgaccgggc cgagccgcga gtgctggacc tccccgaacc ccgccacgag
    18241 gtgctggccg acgcggcaca gcgagcgcgt gccgtggagc tggtggtgcg ggatcggaca
    18301 gcggggcgcg agtgaatccg gacacggccg cgaaaaccgt tcgacgccga cccgtacact
    18361 gggttcgtgg tcaacagggc attggtgcgg atccagagag agtagccgcc cgccccgcat
    18421 cgcacgcggt gccggggcgc tccagcacgt ccacctgacc gcccccgtat ccgggagttc
    18481 tcttgatcac ggccactggc cttgagctgc gcgccggttc gcgcatcctg ctcaacggcg
    18541 ccaccctccg catccagtcc ggcgaccgca tcggcctcgt cggccgcaac ggcgcgggca
    18601 agaccacctc gctgaaagtc ctcgcgggcg agggcgaacc gcacgcgggc gacgtccggc
    18661 gcagcggcga actcggctat ctgccgcagg acccgcgcga gggcgacctg tcggtcaccg
    18721 cgaaggaccg cgtgctgtcc gcgcgcgggc tcgacaccct gctgcgcgac atggaaaagg
    18781 cgcagacctc gatgtccgag ctggtcgacg acaagcagcg ggacaaggcg atcaaccgtt
    18841 acgcgcggct cgaagagcgg ttctcctcgc tcggcgggta cgccgcggag agcgaggcgg
    18901 cgcggatctg ctcgaacctc gggctcgccg accgcatcct gtcccagacg ctcagcacgc
    18961 tgtccggcgg tcagcgccgc cgcgtcgagc tggcgcgcat cctgttcgcc gccgccgagg
    19021 cgggagcggg cggcaagtcc gagacgatcc tgctgctgga cgagccgacc aaccacctcg
    19081 acgccgactc gatcaactgg ctgcgcggct tcctcaagca gcacgacggc gggctcgtgg
    19141 tgatcagcca cgacgtcgaa ctgctcggcg acgtcgtgaa caaggtgtgg ttcctcgacg
    19201 ccacgcgcgg cgagatcgac atctacaaca tgagctggca gcgctatctc gacgcgcgcg
    19261 ccaccgacga gaagcgccgc cgccgcgagc gcgcgaacgc cgagaagaag gcgtccgcgc
    19321 tgcaggcgca ggccgccaaa ctcggcgcga aggcgaccaa ggccgtcgcg gccaagaaca
    19381 tggcccggcg cgcggagcag atgctctcct cgctcgacga gacgcgccag gcggacaagg
    19441 tcgcccggat caagttcccg gagcccgcct cgtgcgggcg cacgccgctg accgcggacg
    19501 gattgtccaa gtcgtacggt tcgctcgaga tcttcaccgg cgtcgatctg gcgatcgacc
    19561 gcggctcgaa ggtcgtggtg ctcggattga acggcgccgg aaagacgaca ttgctccggc
    19621 tgctcggcgg aatggaaacg ccggacaccg gatccgtcga accgggtcac ggattgcgtt
    19681 tgggctatta cgcacaggaa cacgaaactc tcgaccacga agcgtcggtg tgggaaaaca
    19741 tccgccatct cgcgccggac accggcgcgc aggagctgcg gaacctgctc ggctcgttcc
    19801 tgttcaccgg cgaacagctc gaccagcccg ccggaaccct gtccggcggc gagaagaccc
    19861 ggctcgcact cgctggactc gtgtccagcc aagccaatgt gctgctgctg gacgaaccga
    19921 cgaacaacct ggacccggcc agccgcgccc aggttctcga cgcgctgcgc agcttcgccg
    19981 gcgcggtcgt gctggtgacg cacgacccgg gcgcggtcga ggcgctcgaa cccgagcgcg
    20041 tgatcctgct tccggacgga accgaggacc actggtccgc ggattatctt gaacttgtcc
    20101 agcttgcctg accgagtgcg tccgttcggg tgcttaccgt gtcgggcaaa gcactggaat
    20161 ggcccaatgt gatcgcggtt tcgatcgttt tagcgctgtc gtctggcaat ccggcgcgta
    20221 gtgttcgatc attgccccgg caggggccgc gaatggcccg gaacaaccac tcggcgggaa
    20281 ggcgatcgac gtggctgatc tcaagaaagg cgcgcggatc accggcaaca cgcgcgacaa
    20341 gctggccgct gacctgaaga agaaatacga gaagggctcg agcatccggg cgctggccga
    20401 atccaccgga cggtcctacg ggttcgtcca ccgggtgctg tcggagtccg gggtccagct
    20461 gcgggggcgc ggcggggcca cgcgagtcaa gaagaagtag cgtcagcgcg gccgctgcgc
    20521 ggggggcgca cggtcgaagc ggtcgtccgg aaggtcagcg cggcgccgag gagtaccagc
    20581 gggtacacga ggtagccgta ccgggtggcc ggagtaagca ggatcaacgc gccgagtccg
    20641 acggcggttc gcgtcagtgc agcggatccc gtcgcggggg gccggcgcgc cagccagatc
    20701 agcatcgcca ctgccgcaac acccaccagc accagggaaa tcacggtgcc ggccggtccg
    20761 gtctgtgcga tcagatgccc gggcagcggg ctcgccgcgg gggagcggac cgcgcccatg
    20821 ccgagcggga agcggatcac gtgctcggtg aacgccgccg ggttcgccag atacaccggc
    20881 agatgcagcg cgatcgtcgt cgcggccagc gcgcccgcga agcgacccgt tgccgcccaa
    20941 ggattttcgc cgcgcgcacg ccggtaaacg aataccgcga gcaccgcggc ggcaggcgcg
    21001 acgatgagtt tcgcgctgat caccagcgcc agcacgaacc cggtccatcc gggacgcccc
    21061 gatgcggcga gcgcgaaggt cagcacgagc aggccgacga tcgcgag
//
