LOCUS       NZ_CP091381            23490 bp    DNA     circular CON 18-AUG-2024
DEFINITION  Amycolatopsis sp. FU40 chromosome, complete genome.
ACCESSION   NZ_CP091381
VERSION     NZ_CP091381.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. FU40
  ORGANISM  Amycolatopsis sp. FU40
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 9944196)
  AUTHORS   Reisman,B.J. and Bachmann,B.O.
  TITLE     Biosynthesis of Apoptolidin Family Glycomacrolides
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9944196)
  AUTHORS   Reisman,B.J. and Bachmann,B.O.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-JAN-2022) Chemistry, Vanderbilt University, 1234
            Stevenson Center Drive; Room 7330, Nashville, TN 37235, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 23-JAN-2022
            Assembly Method                   :: Flye v. 2.9
            Assembly Name                     :: NFU40_flye_2.9
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 47.0x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021903635.1-RS_2024_08_18
            Annotation Date                   :: 08/18/2024 04:30:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,491
            CDSs (total)                      :: 9,417
            Genes (coding)                    :: 9,360
            CDSs (with protein)               :: 9,360
            Genes (RNA)                       :: 74
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 57
            CDSs (without protein)            :: 57
            Pseudo Genes (ambiguous residues) :: 0 of 57
            Pseudo Genes (frameshifted)       :: 7 of 57
            Pseudo Genes (incomplete)         :: 50 of 57
            Pseudo Genes (internal stop)      :: 5 of 57
            Pseudo Genes (multiple problems)  :: 5 of 57
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:13:09
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 115753
            Orig. end                         :: 139243
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP091381.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Brian O. Bachmann,
            Vanderbilt University.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23490
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23490
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23490
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13490](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13490)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(229..1704)
                     /locus_tag="L3Q65_RS01785"
                     /old_locus_tag="L3Q65_01785"
     CDS             complement(229..1704)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075008.1"
                     /locus_tag="L3Q65_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01785"
                     /product="flotillin family protein"
                     /protein_id="WP_182890864.1"
                     /transl_table=11
                     /translation="MEIWVIVVIAVVAVILLFGLLRILYKVAEPNEALIISGWGVRVER
                     TETADSLGFKIVTGRGVNVLPGFQTARRLSLDTRGVNLQVSCVTKQGLPVTVRAVVIYK
                     VGDDFASIANAARRFLDQQKGMNDTIHELFSGHLRSIVGGLTIEEMIHNRDALTGEVRQ
                     SSATEMIKLGLIVDSLQIQEIDDESGYIVNLGKPHAAAIAAAARIAEAQRDQEATEAEQ
                     VAAARKAGAIRESQIQQAGYQAEVDQAKAKASQSGPLAEATARQEVVVQETRAAELEAA
                     LSEQRLQSQVRKPADAKAYETRTTADAERDAQIARAQAQAKETELRAGADATRVKTAAD
                     AEAQATKARAEASASATKATGEAEAAAAKAKGLADAEAAKAKGLAEAEAAKAKGLAEAE
                     SIKARAAALAENQEAVVAQQLAERWPEIVEAGAQAFGNVDHMVVLNGADGMSDMFTKAL
                     SLGGTGLGLARQLMDAMGPKQSGSDGGLAPRED"
     gene            complement(1771..1980)
                     /locus_tag="L3Q65_RS01790"
                     /old_locus_tag="L3Q65_01790"
     CDS             complement(1771..1980)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657738.1"
                     /locus_tag="L3Q65_RS01790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01790"
                     /product="hypothetical protein"
                     /protein_id="WP_237598648.1"
                     /transl_table=11
                     /translation="MIGSRGRVTGTVGPGLIGEVLLSVRGGTEAFYAYPADPDTSFPVG
                     TPVLVVDFEPPRTVYVERWQPLRA"
     gene            complement(1977..3998)
                     /gene="pknB"
                     /locus_tag="L3Q65_RS01795"
                     /old_locus_tag="L3Q65_01795"
     CDS             complement(1977..3998)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075012.1"
                     /locus_tag="L3Q65_RS01795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01795"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_237598649.1"
                     /sec_met_domain="Pkinase (E-value: 1.5e-46, bitscore:
                     157.9, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTQPSLVGTLLERRYRVDQLLARGGMSAVYRGLDTRLDRAVAI
                     KIMDPRFADDRSFVDRFVREARSAAQLHHPNVVAVHDQGFDTPAGQDSGLAFLVMELVN
                     GGTLRDLLDEQGQLDVSLALSVAEPVLAALAAAHAAGLVHRDVKPENVLIGRSGQLAGG
                     VVKVGDFGLVRAVASAGTTSSSVILGTVGYLAPEQVATGDTTARSDVYSAGILLYEMLT
                     GRLPYTGDTAISVAYRHVNDDVPRPSELRPDLPPVLDDLILRATRRDPEQRPADGGEFL
                     AQLQAARAELGLQPVAVPVPPPPDGDRVSDVERTLPNIPAVQQNVPLGQQTMPVSGPRG
                     TRAMTRAVPASPPPPAPPRAAPAAAPDEPRKPRDKRKLIALAVAGVLVLGGLIGAFAFI
                     LSDSKVTTTTVPKLAGLTQAEAGDQLRAAKLNPRYSQEFDNTVEANKVIKVDPAPGTTL
                     DQDATVSVVVSKGKPKVPNIQVGTALDTAAKAIQEQKLTVVQGTPEYSDTAPQGTVVSV
                     SPAAGTPVDVGGQVTLVLSKGPEPLPPVPDVTGRSKDEAFQILKQAGFQPQDGGEEFSQ
                     TVPAGAVTRTDPGAGSPGTKKVKVYVSNAVQVPDVRYRPFDQAADLLKQAGLDVDRKGG
                     DGNGHGHGGGFSFVLEQDPAPGSFVPKGTKVKIRGFGG"
     gene            4091..4459
                     /locus_tag="L3Q65_RS01800"
                     /old_locus_tag="L3Q65_01800"
     CDS             4091..4459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657740.1"
                     /locus_tag="L3Q65_RS01800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01800"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_182890862.1"
                     /transl_table=11
                     /translation="MSGIPVADDILDAAVAVKPLPEVAAALGVSANKVRQMLRDGELIA
                     VRRKGELCVPGDFFVKDGVVKGLGGTITVLADSGFSRTEMLRWLFTADDTLPGSTPINA
                     LRTSHGTEVKRRAQAMAF"
     gene            4612..6780
                     /locus_tag="L3Q65_RS01805"
                     /old_locus_tag="L3Q65_01805"
     CDS             4612..6780
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L3Q65_RS01805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="L3Q65_01805"
                     /product="hypothetical protein"
                     /protein_id="WP_237598650.1"
                     /transl_table=11
                     /translation="MGGRVSGRRRALVSAVLVLGGSALLPPPAVAETVPFAAAPRAREV
                     TLVTGDRVTVFPGPNGATNYALSSPPRTAFQSYQADGGDRYVIPSDAVPFLGKLDKALF
                     DVTALARTQPGNTPLEVTFPAGAAPAALPGITLTSSAGNTATGYLASAAEFTADLHRRL
                     ADDASAGRPAGSSALPATIRLAGAPREQQPRYPMKILELRLADLRGRSVNGIVSLINTD
                     SSAKLLRHVDVDGVTRIAVPEGRYAASATFSDFDSTGSVVATRTSWLEGFVVGDSPDVQ
                     TLTVEEKYATAEVKVAAPKSTTQDLLTANFFREDSTGRGFAIGIAGSRTKQYVRPVAKP
                     DQGLLHYVVQWGGKAPKPEDRYRVDLSFATEGISENQSFSTEDSELATVRDRMYADPAD
                     KMPVAIDSGPVDPVIQRHGLGASGFFVPAPGVLTDYLGTSHTKEWVQYEQKGSSYQLMT
                     ADPHPYRPGSTTTVDWSRGPLSAGLGQWRRDRQCEACYSGGTVSVAIPELRDSVPDHTA
                     IPLFYAPRLHFTLYRDEQQVFDQAGAYGASVEVPKTRATFRGVLDVDRTAVPGVSQAGK
                     LRTELTLQYDPAAGAALPNPHRCRASDPAQPCRILGALTVDYRLASDLSTTSSSPVQVL
                     ELHVGHASYSGAGSHSPITSATVSVSVDNGATWQPAQVFGLFGEYAAVWRNPPAGTSPS
                     LKVTARDLAGNAITQTISNAYTVGKAER"
     gene            6777..7895
                     /locus_tag="L3Q65_RS01810"
                     /old_locus_tag="L3Q65_01810"
     CDS             6777..7895
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020646995.1"
                     /locus_tag="L3Q65_RS01810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01810"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_237598651.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2e-06, bitscore:
                     26.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVLAVLVLLGALVPSVASAAPRDVCGPAAPGFARCYAKVDSRS
                     ALRATGYSPADLRSAYRLPDTGGAAETIAIVDAGDAPTAEADLAVYRQTYGLPPCTTAN
                     GCFRKVNQNGDATPLPPRQGDWPVETALDLDMASAACSQCKILLVEGDDASFEALGASV
                     DTAVKLGATIVSNSYGAPESHWSAEFAAHYQHPGVAIVASSGDGGFDAPSAPAVYASVI
                     AVGGTSLSKADNERGWTESVWTGASSGCSAWVAKPSWQKDPNCPGRTVADVAAVADPAT
                     GPAVYETTVLSGWRVVGGTSASAPLIAGVIALAGHHDRYPDASRLYSGQLNDVVSGNNV
                     GFEDCGGDYLCTGVPGYDGPTGNGTPDGLAAF"
     gene            complement(7780..9024)
                     /locus_tag="L3Q65_RS01815"
                     /old_locus_tag="L3Q65_01815"
     CDS             complement(7780..9024)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020671595.1"
                     /locus_tag="L3Q65_RS01815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01815"
                     /product="MFS transporter"
                     /protein_id="WP_237598652.1"
                     /transl_table=11
                     /translation="MSSRYRFAAYLTGATAARTGDELSGPAVLLLGVGASGAVAGSALL
                     AGLTVAAAMGGPLLGAVLDRSRMPGRILAVGLVGYAVGLTAITVLFGAVPFALVVAIAV
                     VTGLLAPAIGGGWTAQVPALVPAAKLGKASTLDAMTFTAAALVGPGLAGVLATTAGAPA
                     AVVLAGVFVLVAVPFAWRLPRSAEKQRPRFREAATVLVRNPALRQSTATSTLSCVGIGM
                     AFVCYPLVGAQRLGSAGYGTLLLVGLSVASLLANAVLSRRSYSPDRAVRLSTIAIGIGL
                     AGAAVAPNAALLVAAVALTGVGEGPQLASLFAVRHREAPPEMRAQVFTTAASIKIAGIA
                     LGNAVAGPLAACSPAAGLAAAAGTQVVAAVAHPLWTVRKQPVRPEFRSRSGRRSPAHQC
                     TGSRRRSLRSRRCFR"
     misc_feature    9032..9049
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.28"
                     /tool="antismash"
     gene            9047..9595
                     /locus_tag="L3Q65_RS01820"
                     /old_locus_tag="L3Q65_01820"
     CDS             9047..9595
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657742.1"
                     /locus_tag="L3Q65_RS01820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01820"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_182890858.1"
                     /transl_table=11
                     /translation="MPGTQPDSAGRSARDAVRRAVALLDVLLTADPSPDSVAAVLVAHG
                     EPQPQLSAREVAELRAAALELREVFAAPDAASAAEVLNALFTAYAGPPRLTAHDDTFGW
                     HLHVDASDDGPWGAWLITSSALALATLLADRQSVPGGLCASPSCGKPFAHLGGGSPRRY
                     CSSRCATRERVAAHRARLT"
     gene            9601..10029
                     /locus_tag="L3Q65_RS01825"
                     /old_locus_tag="L3Q65_01825"
     CDS             9601..10029
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075019.1"
                     /locus_tag="L3Q65_RS01825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01825"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_182890857.1"
                     /transl_table=11
                     /translation="MEILSLADFTSFVRANPLGVVATTASNGHPEAALVSFAIAPDGSL
                     LFNAHRTARKVANLRAHPRAAAVIGCTGTVSLQVEGEAAIESGTARRDAGQVYLEQFPG
                     SRALDEDFALIRLTPDWLRSYDASVEPARVSEGVPVWH"
     gene            complement(10001..10927)
                     /locus_tag="L3Q65_RS01830"
                     /old_locus_tag="L3Q65_01830"
     CDS             complement(10001..10927)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005463706.1"
                     /locus_tag="L3Q65_RS01830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01830"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_237598653.1"
                     /sec_met_domain="phytoene_synt (E-value: 5.3e-114,
                     bitscore: 379.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 8.9e-65,
                     bitscore: 217.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSELDAAGIAEPALRAAYTECRRINAHHGRTFFLATRLLPARARP
                     AAHALYGFARMADELVDNPEPGTDPAVALDKVAGLVDEVYDGRAPVDPVLAALADTVRR
                     YDIRRDLVDAFLHSMRMDLTVAEYATYADLGEYIYGSACVIGLQMLPVFGTVGPLEEAA
                     PSAAALGEAFQLTNFLRDVGEDLDRGRLYLPAEELAAFGVDRERLLDARRQDRSDPRVR
                     AALAVAVSRTRAVYRRAEEGISLLRPESRPCVRTAITLYEGILDEIEAMDYAVLNRRAA
                     VGKGRRVAVAVSALAQRGLSARPGRPR"
     gene            complement(10924..12399)
                     /gene="crtI"
                     /locus_tag="L3Q65_RS01835"
                     /old_locus_tag="L3Q65_01835"
     CDS             complement(10924..12399)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637666.1"
                     /locus_tag="L3Q65_RS01835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01835"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_182890855.1"
                     /sec_met_domain="DAO (E-value: 4.2e-16, bitscore: 58.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVNGPADHVVVVGAGLAGLSATLHLLGAGRRVTLLEQQKMPGG
                     RAGQQDFGANAVDTGASVLTMPELVDEALHAVGESLADTVPLTRLDPAYRARFADGSTL
                     AVHTDGEAMEAEIRSFAGPAEADGYRRLRRWLTDLYAAQKDHFIGANFDSPLDLVRPEL
                     GKLAALGGFGRLGPRVSSFLRDERVRRLFSFQALYAGLDPTRALGAYGVIAYMDTVGGV
                     YYPRGGMGAIARAMSDAATRAGAELRFGTEAAWLERVSSRVRAVRTRSGERIECDAVVL
                     ATELSAAYRLIGARPRRVLPLKYSPSAFVLHGHADRSWPELDHHTIFFGQAWERTFAEI
                     VREGKLMSDPSLLVTRPTATEPTLAGDGGEIISVLAPAPNLNTGPIDWARVGPAYREEL
                     LRTLESRGLTGFRDEYIVDEQLTPADWAARGLAAGTPFSLAHTFPQTGPFRPANLVRAA
                     ENVVLAGCGTTPGVGIPPVLISGRLAAERITGR"
     gene            complement(12399..13490)
                     /locus_tag="L3Q65_RS01840"
                     /old_locus_tag="L3Q65_01840"
     CDS             complement(12399..13490)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016332689.1"
                     /locus_tag="L3Q65_RS01840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01840"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_182890854.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-44, bitscore:
                     151.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAPGFDADLPAHVERALADFLGRAGSEILRTEPSVAAGIEALSG
                     FVLGGGKRIRPTFAWWGWRGAGGAASGPLAEGALQAVASLELIQACALIHDDLIDSSDS
                     RRGRPTVHVAAEKLHADRGWLGSPSVFGLASAVLVGDLALAWADDMFADAPLPAETIAA
                     ARPAWRAMRTEVLAGQYLDVRTQAVGDASPEAALRIDRLKTAAYTVQRPLHLGASLAGA
                     DDRLIATLLEFGGDVGVAFQLRDDLLGVFGDPSVTGKPAGDDLREGKRTLLVALGLQLA
                     AEKGDHTAAKAIADAIGAADLTNGTVDQVREALTSVGAVAAVERRIDELTASANAALDR
                     AHLAEPAPSALAELIRLATQRKF"
     gene            complement(13562..14206)
                     /gene="merB"
                     /locus_tag="L3Q65_RS01845"
                     /old_locus_tag="L3Q65_01845"
     CDS             complement(13562..14206)
                     /EC_number="4.99.1.2"
                     /GO_function="GO:0018836 - alkylmercury lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="merB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020657746.1"
                     /locus_tag="L3Q65_RS01845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01845"
                     /product="organomercurial lyase"
                     /protein_id="WP_237598654.1"
                     /transl_table=11
                     /translation="MSSEDDLAWDEDVRVAVYRAFSSRGRPPTAPELADAAHGSLAVAK
                     QALHRMADPRWLWLDECEHVALAAPFAAVPLGFAVMGEHTMWWGGCAWDSFAIPHLVSG
                     EPEVLVATRCPGCGEPSALVVRRDRPPSGTQVAYFPASPEQLAGDRGKQRLYCAESCVD
                     SPGELLGLDALWHLAKDWYEGCLEPGYRPRGPAEAAEYFAASGRPDAFRSG"
     gene            14311..15198
                     /locus_tag="L3Q65_RS01850"
                     /old_locus_tag="L3Q65_01850"
     CDS             14311..15198
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075028.1"
                     /locus_tag="L3Q65_RS01850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01850"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_182890852.1"
                     /transl_table=11
                     /translation="MTSVIERLRGDGPAFSVEFFPPRDEADEAVLWKAIRELEPLDPAY
                     MSITYGAGGSSRDGTIRSIARVATETTLCPMAHLTAVDHSVAELRNVIGWYAAVGVRNI
                     LALRGDPPGDVYGDWVPHPEGLTYAEELVGLVRSLGDFCVGVSAFPYGHPRSADLESDT
                     KHLVRKFRAGADFAIAQLFFEAEDFLRLRDRVAAAGCDALVLPGIMPLTTLRTLHTTIK
                     LSGAPASQRLLDRLEPFSDDPKAFRAAGIDWVTELCEKLIAEGVPDLHFYTFNRSKATR
                     EVVTRLGLVPARTY"
     gene            15339..17018
                     /locus_tag="L3Q65_RS01855"
                     /old_locus_tag="L3Q65_01855"
     CDS             15339..17018
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075033.1"
                     /locus_tag="L3Q65_RS01855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01855"
                     /product="DUF885 domain-containing protein"
                     /protein_id="WP_237598655.1"
                     /transl_table=11
                     /translation="MASTEQSVPEICDRYVDDYVAVDPVAATMLGVAGYDDQLTDYSPT
                     GHDARADLARRALAAVTAAEPADAGERVAKAVFTERIGLELEIHDAGLDAASLNVIESP
                     VQGLRMVFDLMPTDTPDDWANVAARLPKVPEALAGVRASLLASADKGRVSALRQVSKVA
                     EQCETWAGLKDGPGFFAGMVADAGVDSLKSDLASGARAADEAFAEFAGFLRAELAPKAP
                     VKDAVGEDTYRLWSRYFIGAELDLREAYEWGWHEFSRLETEMRAVANRIKPGSTPAEAA
                     AVLDADPRYRIQGRPQFEAWMQQLSDDALKSLRGKHFDIPDRLMALECKIAPPGGGVGA
                     YYTGPSEDFSRPGRMWWSLPADRNDFTTWREVSTVYHEGVPGHHLQIATAVNQAETLTK
                     YQRLMTFISAHGEGWALYAERLMEELGYLSDDGNLLGMLSEQLFRAARVVVDLGMHLEL
                     EIPAGTGFHEGERWTPDLGLEFMLTRTITDHAHIHDEIDRYLGWPGQAPAYKLGERLWL
                     AARDEARARQGSAFDIKQFHTKALQMGGMGLDTLREQLAQLD"
     gene            17069..17584
                     /locus_tag="L3Q65_RS01860"
                     /old_locus_tag="L3Q65_01860"
     CDS             17069..17584
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662726.1"
                     /locus_tag="L3Q65_RS01860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01860"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_182890850.1"
                     /transl_table=11
                     /translation="MFTAQLIETTRLDLLPLSVSHAEEMASVLSDPALHTYIGGAPDSA
                     AALRARYQRMTAGSPDPAVSWLNWVIRLRDSGLVGTVQATVSRAVAEIAWVVGTPWQGR
                     GIATEAARGLVAWLDQRPVDEIIAHIHPENRASAAVAAAIGLSATGEWQDGEIRWAANP
                     LIVSPASG"
     gene            17765..18661
                     /locus_tag="L3Q65_RS01865"
                     /old_locus_tag="L3Q65_01865"
     CDS             17765..18661
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009075037.1"
                     /locus_tag="L3Q65_RS01865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01865"
                     /product="DMT family transporter"
                     /protein_id="WP_182890849.1"
                     /transl_table=11
                     /translation="MSVAVPSRARSSAALVLAGVLWGTGGLSGSLLAQQAGLHPLAVAT
                     YRLLIGGAASAAYVALTGGLRLPAKETWRRLLLVGALFALFQASYFAAVALSSVSVATM
                     TTIGAAPVVLTMVSAVQRRRAPQLWTLVSVGGSVAGLVLLRWSPETATSPARLVGGLGF
                     ALLAATGFAVLTLVTAEPVNGLEPLATTAFGCLTGGLLLTPAALWLGMSLPANADVLLL
                     AVYFGVVPTAVAYAAYFRGLGGAHPVLGALSALLEPLTGTVLSVVFLHERLSTFAWGGA
                     VLLVAALAVGYWRPEPR"
     gene            18737..19735
                     /locus_tag="L3Q65_RS01870"
                     /old_locus_tag="L3Q65_01870"
     CDS             18737..19735
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020673194.1"
                     /locus_tag="L3Q65_RS01870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01870"
                     /product="DUF3558 family protein"
                     /protein_id="WP_182890848.1"
                     /transl_table=11
                     /translation="MITENRIFRAAALAAGATLLAALAGCGGSTAGTAAAGSPASEAKP
                     PITDPAVQAAALRTVDPCALLDAKTLGALGTPDQSSLSSSEWGECSVNVKDSGGKTVEL
                     VLRVGDQLIMSKDPAEKLEGLPLVVDNDKPGSCWVSVVTSFEQSLGITFQAKAPGGDAC
                     ALGRAALAKVVQALHSTPPQYQQMPGSVLTTDPCAVAGKQAVETALGQKSFVEPKSLHE
                     CDFWSGDDTHYPQVSVHLYQGLPADAEDGQPADLGSGVTAIQKKDEDSSVVSCDATWRK
                     IETPKDDEAHGYGEIVSVQFSGEPASGLDTGTACTKAVAVAKTVAPSLGRA"
     gene            complement(19834..20409)
                     /locus_tag="L3Q65_RS01875"
                     /old_locus_tag="L3Q65_01875"
     CDS             complement(19834..20409)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064527.1"
                     /locus_tag="L3Q65_RS01875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01875"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_182890847.1"
                     /transl_table=11
                     /translation="MTAMSSSGCSRYVQLSADEFRSRLPEALAIYVNAMRYPEGTAEQR
                     APMWLTHALREGWRCIAALDDNGVLLGIAYGYKGRAGQWWHEQVRHGLTRRSGTEEAER
                     WLADYFELTEIHVRPENQGKQIGEDLLRRLLDGVPSANVLLSTPEGTSRAWKLYRRMGF
                     VDVLRDYQFTGDPRPFAILGRALPLEAR"
     gene            complement(20406..20930)
                     /locus_tag="L3Q65_RS01880"
                     /old_locus_tag="L3Q65_01880"
     CDS             complement(20406..20930)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005156538.1"
                     /locus_tag="L3Q65_RS01880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01880"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_182890846.1"
                     /transl_table=11
                     /translation="MSTHDHPAVAKVTAALGEAGLHAAADGVRVLPAEARTAAQAAEAL
                     GVPVGAIANSLVFRARRNDGAEVALLALTSGAHRAEEFRLAELAGVAEVGKADAAFVRE
                     HTGQPIGGVAPIGHPERLVTLVDTALRGYAEVWAAAGHPKSVFPTTFDALVTLTGGTPG
                     DLAGEGEDGRL"
     misc_feature    complement(21034..21049)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: strong, score: 28.4"
                     /tool="antismash"
     misc_feature    21035..21048
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 22.19"
                     /tool="antismash"
     misc_feature    complement(21035..21048)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.17"
                     /tool="antismash"
     gene            21481..22188
                     /locus_tag="L3Q65_RS01885"
                     /old_locus_tag="L3Q65_01885"
     CDS             21481..22188
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037499.4"
                     /locus_tag="L3Q65_RS01885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01885"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_237598656.1"
                     /transl_table=11
                     /translation="MESGLGSSPEPVPSASAVNPAAPATNPALPFASENTPAAAPQPER
                     APTPKPTVHHVPEAPVPSGPPPRQVVHRTRAAVRPSAEPSARRSGAKGQPQLPLSLRPP
                     APPEAVALLAQANRGLDHAENERDPAERFIGAYLAALRGAGAVLAVRGRPRRGRGRPAS
                     GWVLLDAVAPELREWSAFFADHSETRAAAEAGISGRVTAELATGLLEATAQFLELVRRV
                     VHGLPMTGEAHVA"
     gene            22178..22942
                     /locus_tag="L3Q65_RS01890"
                     /old_locus_tag="L3Q65_01890"
     CDS             22178..22942
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020644807.1"
                     /locus_tag="L3Q65_RS01890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="L3Q65_01890"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_182890845.1"
                     /transl_table=11
                     /translation="MSRELGTVDHGRLLEAFSVEAHLLGEVAHSASPDSPVPTAPGWTL
                     NELLKHVGSVYWQVLGWIREGRRPEPWREPLPGQPVADFYSAARTELEAALADHDPATR
                     AATWWSADPTHGFWRRRMLHETLVHRVDAENAAGTGDSTVPDDLAADGVDEALTLYFGH
                     KLTTMGVSGTRNGTVGFHTGGHSWIARAGPGETEAWRCSSREADAADAIVTGSPANVYL
                     WLWGRVPVTMVHTDGDHELSAQAWALLRLATR"
     misc_feature    23045..23060
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.58"
                     /tool="antismash"
     misc_feature    complement(23124..23134)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
ORIGIN
        1 gcgaatacac cgcgatccgc agcgtcatcg cctccggcca cacctcgacc gcgcgcagcg
       61 ccacgatggt gcgctcggac cggcccagcg gcgtcgccca cggcaccagc gcgggcacga
      121 tgtggtcggc gggcgggccg gtccacggac ggccctcgta gccgaacagc tcccgttccc
      181 ggaccgggaa caggggtcgc tcgcgaggac cgtccgtgaa gaagctcatc agtcctcgcg
      241 aggggcgagg ccgccgtcgg aaccggactg cttggggccc atggcgtcca tcagctggcg
      301 ggcgaggccg aggcccgtgc cgccgaggga gagcgccttg gtgaacatgt ccgacatccc
      361 gtccgcgccg ttcaggacca ccatgtggtc gacattgccg aaggcctgtg cgccggcttc
      421 gacgatttcc ggccagcgct cggccagctg ttgtgctacc acagcctcct ggttctccgc
      481 cagtgcggcc gcgcgcgcct tgatcgactc ggcctcggcg agtcccttcg ctttcgccgc
      541 ctcggcttcg gccagacctt tggctttcgc cgcttcggcg tccgcgagcc ccttcgcctt
      601 ggccgccgcc gcttcggcct cgccagtggc tttcgtcgca ctcgcgctgg cttccgcgcg
      661 tgccttcgtg gcctgcgctt cggcgtccgc cgcggtcttg acccgggtcg cgtccgcgcc
      721 cgcccgcagt tcggtttcct tcgcctgtgc ctgcgcgcgg gcgatttgcg cgtcgcgttc
      781 cgcgtcggcg gtggtgcgcg tttcgtacgc cttcgcgtcg gccggtttgc ggacctgcga
      841 ctgcagccgc tgctcggaca gtgccgcctc gagttcggcg gccctggtct cctggaccac
      901 gacctcctgg cgcgcggtcg cctcggccag cggaccggac tggctcgcct tcgccttggc
      961 ctggtccacc tcggcctggt acccggcctg ctggatctgg ctttcccgga tcgcgcccgc
     1021 cttgcgcgcg gcggcgacct gctcggcctc ggtggcctcc tggtcgcgct gggcctcggc
     1081 gatccgcgcg gcggcggcga tcgcggccgc gtgcggtttg ccgaggttga cgatgtagcc
     1141 ggactcgtcg tcgatctcct ggatctgcag cgagtccacg atcagcccga gcttgatcat
     1201 ctcggtggcc gacgactggc ggacctcgcc ggtcagcgcg tcgcggttgt ggatcatctc
     1261 ctcgatggtc agcccgccca cgatcgaccg caggtggccg gagaacagct cgtggatggt
     1321 gtcgttcatg cccttctgct ggtcgaggaa ccggcgggcg gcgttcgcga tcgaggcgaa
     1381 atcgtcgccg accttgtaga tcacgaccgc gcgcacggtg accggcagac cctgtttcgt
     1441 cacgcacgag acctgcaggt tcacccctcg ggtgtccagc gacagcctgc gcgcggtctg
     1501 gaagcccggc agcacgttca cgccgcggcc ggtgacgatc ttgaacccga ggctgtcggc
     1561 ggtctcggtg cgctcgaccc ggacgcccca gccggagatg atgagcgcct cgttcggctc
     1621 cgcgaccttg tacaggatcc gcaggagccc gaacagcagg atcacggcca cgaccgcgat
     1681 caccacgatg acccagattt ccatagccct cgccgcactt tccgtattca gctggcacgg
     1741 cgctgaggcg ccgtcagcac tgcgacgcgg tcaagcgcgc aacggttgcc acctttccac
     1801 gtagaccgtg cgcggaggct cgaaatcgac caccagaacg ggtgtaccga cggggaaact
     1861 ggtgtccggg tcggcgggat aggcgtagaa ggcctcggtg ccgccgcgga cgctgagcag
     1921 cacctcgccg atcagccccg gcccgacggt gccggtcacc cggccgcggc tgccgatcat
     1981 ccgccgaacc cccggatctt gaccttggtg cccttgggca cgaacgagcc gggggccggg
     2041 tcctgctcca gcacgaagct gaagccgccg ccgtgcccgt ggccgttgcc gtcgccgccc
     2101 ttgcggtcga cgtcgagccc ggcttgtttg agcaggtccg cggcctggtc gaacgggcgg
     2161 taccggacgt ccgggacctg caccgcgttc gagacgtaga ccttgacctt cttggtcccc
     2221 ggcgaacccg cgcccgggtc ggtgcgggtg accgcccccg cgggcacggt ctgcgagaac
     2281 tcctcgccgc cgtcctgcgg ctggaatccg gcctgcttga ggatctggaa cgcctcgtcc
     2341 ttcgaccgcc cggtgacgtc cgggaccggc ggaagcggtt ccggcccctt ggacagcacc
     2401 agcgtgacct ggccgccgac gtccaccggc gtgcccgccg ccgggctcac gctcacgacg
     2461 gtgccttgcg gcgcggtgtc gctgtattcc ggcgtgccct ggacgaccgt gagcttctgc
     2521 tcctggatcg ccttcgccgc cgtgtcgagc gcggtgccga cctggatgtt cggcaccttc
     2581 ggcttgccct tcgacaccac gacggacacg gtggcgtcct ggtcgagcgt ggtgccaggg
     2641 gccggatcca ccttgatgac cttgttggcc tcgaccgtgt tgtcgaactc ctggctgtag
     2701 cgcgggttca gcttcgccgc gcgcaactgg tcgcccgctt cggcctgggt cagcccggcg
     2761 agcttcggca ccgtcgtggt cgtgaccttg gaatcgctga ggatgaacgc gaacgcgccg
     2821 atcagcccgc cgaggaccag gaccccggcg accgcgagcg cgatcagttt gcgcttgtcc
     2881 cgcggctttc gcggctcgtc cggcgcggcg gcgggcgcgg cgcgcggcgg tgccggaggg
     2941 ggcggcgacg cgggcacggc gcgggtcatg gcgcgcgtgc cgcgaggtcc ggagaccggc
     3001 atggtctgct ggcccagcgg gacgttctgc tggacggccg ggatgttcgg gagggtgcgt
     3061 tcgacgtccg acacccggtc gccgtcgggc ggcggaggca ccggcaccgc gaccggctgc
     3121 agccccagtt cggcgcgcgc ggcctgcagc tgggccagga actcgcctcc gtcggccggg
     3181 cgctgctccg gatcgcggcg ggtggcgcgc aggatcaggt cgtcgagcac cggcggcagg
     3241 tccggccgca gctcgctcgg ccgggggacg tcgtcgttca cgtgccggta ggcgaccgag
     3301 atcgcggtgt cgccggtgta gggcagccgg ccggtgagca tctcgtacag caggatgccc
     3361 gccgaataga cgtcgctgcg ggccgtggtg tcgccggtgg cgacctgttc gggggccagg
     3421 tagccgacgg tgccgagaat gacgctggag ctggtggtgc ccgcgctggc caccgcgcgg
     3481 accaggccga agtcgccgac cttgaccacg ccgcccgcca gctgcccgct gcggccgatc
     3541 agcacgttct cgggcttgac gtcgcggtgc accagcccgg cggcgtgcgc ggcggccagc
     3601 gcggccagca ccggctccgc gacgctcagc gcgagcgaga cgtccagctg gccctgttcg
     3661 tccagcagat cgcgcagcgt gccgccgttg accagctcca tcaccaggaa ggcgaggccg
     3721 gagtcctggc ccgccggggt gtcgaagccc tggtcgtgca cggctaccac gttcgggtgg
     3781 tgcaactggg cggccgaacg cgcttcgcgc acgaaccggt cgacgaacga ccggtcgtcg
     3841 gcgaaccggg gatccatgat cttgatcgcc accgcccggt cgagacgggt gtcgaggccc
     3901 cggtagacgg ccgacatccc gcccctggcc agcagctggt caacgcggta ccggcgttcg
     3961 agcagggtgc cgacgaggct gggctgggtg cgcgtcacgg tgggcaatcg tacggaaggc
     4021 cgcgcgtgcc ggggcgggtc acccgtgcgt agcagtggtc cggacggggg aatgtggcac
     4081 agtgtcacgt gtgagtggga ttcctgtcgc cgacgacatc ctcgacgccg cggtcgcggt
     4141 caagccgttg ccggaggtgg cggccgcatt gggcgtgtcg gccaacaagg tgcgccagat
     4201 gctgcgggac ggcgaattga tcgctgtccg gcgcaagggc gaactctgcg tgcccggcga
     4261 tttcttcgtg aaggacggcg tcgtcaaggg actgggcggc accatcaccg tgctcgccga
     4321 ctccgggttc agccgcaccg agatgctgcg ctggctcttc accgccgacg acacgctgcc
     4381 gggcagcacg ccgatcaacg cgctgcgcac cagccacggc accgaggtga agcggcgcgc
     4441 gcaggcgatg gcgttctagc tccttcccgc attgctcgcc ggcgggctga caacaattgc
     4501 ccgtccggac agaaaccgcg ttttccgttg acgcggtcaa ttcgctcggt ccatcgtcgt
     4561 gaaccgtcct gaaaatcctg ctcggccgca tgctggagag gagcatcggg catgggagga
     4621 cgggtttccg gaagacgccg cgcgctcgtg tcggccgtcc tggtgctggg cggttccgct
     4681 ttgctgccac cgcctgcggt cgccgagacc gtgcccttcg cagcggcgcc gcgagcgcgg
     4741 gaagtgacgc tggtgacggg ggaccgggtc acggttttcc cgggaccgaa tggcgctacg
     4801 aattacgccc tttcgtcgcc gccgcgcacc gcttttcagt cgtatcaagc cgacggcggc
     4861 gaccgttacg tcattccgag cgacgccgtt ccgtttctcg gaaagctgga caaagcactg
     4921 ttcgacgtca ccgcgctggc gcggacgcag cccgggaaca cgccgctgga ggtcaccttc
     4981 ccggccggcg cggccccggc ggcgctgccc ggcatcacgc tcacctcgtc cgctgggaac
     5041 accgcgaccg ggtacctcgc ttccgccgcc gaattcaccg ctgacctgca ccgacgcctc
     5101 gcggacgacg cgtccgccgg acgtccggcc ggcagcagcg cgctgcccgc gacgatccgg
     5161 ctggccggtg cgccccgcga acagcagccg cgctacccga tgaagatcct cgaactccgc
     5221 ctcgccgatc tgcggggccg ctcggtcaac ggcatcgtct cgctgatcaa caccgattcc
     5281 tcggccaagc tgctgcggca cgtcgacgtc gacggcgtca cccggatcgc ggttcccgag
     5341 gggcgctacg ccgcgtccgc gaccttctcc gacttcgaca gcacgggaag cgtggtcgcc
     5401 acgcggacgt cgtggctcga gggcttcgtc gtcggcgatt cgccggacgt gcagaccctg
     5461 accgtcgagg agaagtacgc gaccgccgag gtcaaggtgg ccgcgccgaa gtcgacgacg
     5521 caggacttgc tcaccgccaa tttcttccgc gaggactcca ccggccgcgg attcgccatc
     5581 ggcatcgcgg gcagcaggac caaacagtac gtgcggccgg tggcgaagcc ggatcagggc
     5641 ctgttgcact acgtcgtgca atggggcggc aaagcgccca agcccgaaga ccggtaccgc
     5701 gtcgatcttt ccttcgccac cgaaggcatc tccgagaatc agtcgttttc cactgaggac
     5761 agcgaactcg cgacggtccg cgaccggatg tacgccgatc ccgcggacaa gatgccggtc
     5821 gcgatcgaca gcggcccggt cgacccggtg atccagcggc acggcctcgg cgcgagcggc
     5881 ttcttcgtcc ccgctcccgg ggtgctgacc gactacctcg gcacctcgca caccaaggaa
     5941 tgggtgcagt acgaacaaaa aggctcttcg tatcagctga tgaccgccga tccgcaccct
     6001 tatcggccgg gcagcaccac gaccgtcgac tggtcccgcg gcccgctgtc cgccggtctc
     6061 ggccagtggc ggcgggaccg gcagtgcgag gcctgctact ccggcggcac cgtttcggtc
     6121 gccatcccgg aattgcggga cagcgtgccg gaccacaccg cgatcccgtt gttctacgcc
     6181 ccgcggctgc attttacctt gtaccgcgac gagcagcagg tcttcgatca ggccggtgcc
     6241 tacggcgcgt cggtcgaggt gccgaagacg cgcgcgacct tccgcggcgt actggacgtc
     6301 gaccggaccg ctgtccccgg cgtcagccaa gccggaaagc tgcgcaccga actgaccctg
     6361 cagtacgacc cggccgcggg tgccgcgttg ccgaacccgc atcgctgccg ggccagcgat
     6421 ccggcgcagc cgtgccggat cctcggtgcg ctgaccgtcg actaccggct ggcttccgat
     6481 ctctccacga cgtcgtcctc accggtacag gtgctcgaac tgcacgtcgg ccacgcgtcc
     6541 tacagcggtg ccggttcgca ttcgccgatc acctcggcga cggtttcggt gtccgtcgac
     6601 aacggggcca cctggcagcc cgcgcaggtc ttcggtctct tcggcgaata cgcagcggtc
     6661 tggcggaatc cgccggccgg tacttcgccc tcgctgaagg taaccgcgcg ggatctcgcg
     6721 ggcaacgcga tcactcaaac gatcagcaac gcctacaccg tagggaaggc cgagcgatga
     6781 aacgcgtcct ggctgtgctg gttctcctcg gtgcgctcgt cccgtccgtc gcgtccgccg
     6841 ccccacggga cgtctgcggt cccgctgctc cggggttcgc ccgctgctat gccaaagtgg
     6901 acagtcggtc tgccttgcgc gccaccggct acagccccgc tgacctgcgt tccgcctacc
     6961 gccttccgga caccggcggc gctgccgaaa cgatcgccat cgtcgacgct ggcgacgccc
     7021 cgaccgccga agcggatctg gcggtatatc gacaaaccta cggcctcccg ccctgcacca
     7081 cggcgaatgg ctgcttccgc aaagtcaacc agaacgggga tgcgacgcca ctcccgccgc
     7141 ggcaaggcga ctggccggtg gagaccgcgc tggatctcga catggcctcc gccgcctgct
     7201 cccagtgcaa gatcctgctg gtagaaggcg atgacgcgtc gttcgaagca ctcggcgcct
     7261 ccgtggacac cgccgtgaaa ctcggcgcga cgatcgtgtc gaacagctac ggcgctccgg
     7321 aaagccactg gtcggccgag ttcgccgcgc actatcagca ccccggcgtc gcaatcgtcg
     7381 cgtcgagcgg cgacggcgga ttcgacgcac ccagcgcgcc cgcggtgtac gcgagcgtca
     7441 tcgcggtcgg cggcacgtcg ctgtccaaag cggacaacga acgcggctgg accgaatcgg
     7501 tgtggaccgg cgcgtcgagc ggatgttcgg cctgggtggc gaaaccgtcg tggcagaagg
     7561 atccgaactg tcccggccgg accgtcgccg acgtcgccgc ggtagccgat cccgccactg
     7621 ggcccgccgt ttacgagacc acagtcctgt ccggctggcg agtagtcggc gggaccagcg
     7681 cgtcggcgcc gctcatcgcg ggagtcatcg cgctggccgg acaccacgac cggtatccgg
     7741 acgcttcgcg gttgtactcg gggcagctca acgacgtcgt cagcggaaac aacgtcggct
     7801 tcgaagactg cggcggcgac tacctgtgca ctggtgtgcc gggctacgac ggcccgaccg
     7861 ggaacggaac tccggacgga ctggctgctt tctgaccgtc cacaacggat gcgcgaccgc
     7921 cgcgaccacc tgcgtccccg ccgccgcggc caatccggcg gcgggggagc aggcggccaa
     7981 cggcccggcc accgcgttcc ccagcgctat cccggcgatc ttgatgcttg ccgcggtggt
     8041 gaacacctgc gcccgcattt ccggcggtgc ctcccgatgc cgaaccgcga acaacgacgc
     8101 cagttgcggt ccttcgccga cccccgtgag cgcaaccgcc gctaccagca gcgctgcatt
     8161 cggtgccacc gccgccccgg caagcccaat accgatcgcg atggtgctca accgcaccgc
     8221 gcggtccggc gaatacgacc gtcgcgaaag gactgcgttc gccagcaacg acgcgactga
     8281 caacccgacg agcaacaacg tcccgtaccc cgcgctgccc agccgctgcg cgccgaccag
     8341 cggatagcag acgaacgcca tcccgatccc gacgcacgac aacgtcgagg tcgcggtgga
     8401 ctgccgcagc gcgggattgc gcacgagaac ggtcgctgct tcacggaatc gcggccgctg
     8461 tttttcggca ctccggggaa gccgccatgc gaacggcacc gcaaccagca cgaacacgcc
     8521 cgcgagaacc actgctgccg gagcccccgc tgtcgtggcg agcactcccg caagtcccgg
     8581 tccgaccaga gctgccgcgg tgaacgtcat cgcgtcaagc gtgctcgcct tgccgagctt
     8641 cgctgccggt acgagcgcgg gcacctgcgc cgtccacccg ccgccgatcg ctggcgccag
     8701 cagccccgtc accaccgcaa tcgctactac cagcgcaaac ggcaccgccc cgaaaagcac
     8761 tgtgatggct gtcagcccca ctgcataccc gaccagcccg accgcgagga tccggccagg
     8821 catgcgtgac cggtcgagca ccgcgcccag caacggcccg cccatcgccg ccgcgaccgt
     8881 gagcccggcc agcaacgccg accccgcgac ggcccccgaa gcacccacgc ccagcagcag
     8941 caccgccgga ccggacaact cgtccccagt gcgcgcggca gtggccccgg tgagatacgc
     9001 cgcgaacctg taacggcttg acatagacaa gatgttacag tggtgtatgc ctggaacgca
     9061 gccggattcc gcgggccgct ccgcccggga cgctgttcgc cgtgccgtag cgctgctcga
     9121 cgtgctgttg acggcggacc cttcgccgga ttcggtagcc gcagtactgg tcgcgcacgg
     9181 agaaccacaa ccccagctct ccgcgcgcga ggtagccgag ctgcgcgccg ctgcgctgga
     9241 gctaagagag gtcttcgccg cgccagacgc cgcgtcggcc gccgaggtgc tgaacgcgct
     9301 gttcaccgcc tacgcgggac ctccgcgcct gaccgcacac gacgacacct tcggctggca
     9361 cctccacgtc gacgcatccg acgacggccc atggggcgcc tggctgatca cgtcctccgc
     9421 gctggcgttg gccaccctgc tcgccgaccg ccaaagcgtc cccggcggtc tgtgcgcgtc
     9481 gccgtcgtgc gggaaaccct tcgcccacct aggcggcggc agcccacgcc ggtactgctc
     9541 ttcccgttgc gccacaaggg aacgagtcgc cgcccaccgg gcccggctaa cctgaccggc
     9601 atggagattc tttccctggc ggacttcacg agcttcgtcc gagccaaccc gctaggcgtc
     9661 gtcgccacca ctgcttcgaa cggccacccc gaagctgccc tggtcagctt cgccatcgcc
     9721 ccagacggat cgctgctgtt caacgctcac cgcaccgctc gaaaggtggc caacctccga
     9781 gcacatccgc gcgccgctgc ggtaatcggc tgcaccggca cggtttcgct ccaggtcgaa
     9841 ggcgaagcag ccatcgaatc cggcactgcc cgccgcgatg caggccaggt gtacctggag
     9901 cagttcccgg gctcccgagc cctcgacgag gacttcgcgc tcattcgcct gaccccggat
     9961 tggctgcgct cctacgacgc cagcgtcgaa ccggcccgag tcagcgaggg cgtcccggtc
    10021 tggcactgag cccacgctgc gccagcgcgg acaccgcgac cgcgacccgt cgccccttgc
    10081 ccactgccgc gcggcggttg agcacggcgt agtccatcgc ttcgatctcg tccaaaatgc
    10141 cttcgtacaa cgtgatcgcc gtccgcacgc acggccggga ttccggccgc agcaacgaaa
    10201 tcccctcctc agcccgccga tacaccgcac gcgtccgcga aaccgccacc gccagcgccg
    10261 cccgcacccg aggatccgaa cggtcctgcc gacgcgcgtc gagcaacctc tcgcggtcca
    10321 ctccgaacgc cgccagctcc tcggcaggca gatacaaccg cccgcggtcg agatcctcgc
    10381 cgacatcccg caggaaattg gtcagctgaa acgcttcccc caacgccgcc gcactcggcg
    10441 cagcttcctc cagcggcccg acggtcccga acaccggcag catctgcagc ccgatcacgc
    10501 aggccgaacc gtagatgtac tcaccgaggt cggcgtaagt cgcgtactcc gcgaccgtca
    10561 ggtccatccg catggaatgc aggaacgcgt cgacgagatc gcggcggatg tcatagcggc
    10621 gcaccgtatc cgcaagggcg gccagcaccg gatcgaccgg tgcccgcccg tcgtaaacct
    10681 cgtcgaccag cccggcgacc ttgtccagcg cgaccgccgg atcggtgccg ggctcggggt
    10741 tgtcgaccag ttcgtcggcc atccgcgcga agccgtacaa cgcgtgcgcg gccggccgcg
    10801 cacgcgccgg aagcagccgc gtggcaagga aaaacgtgcg gccgtggtgc gcgttgatgc
    10861 gccggcactc cgtgtaggcg gcacgcagcg cgggctcggc gatgccggcc gcgtcgagct
    10921 cgctcaccgg ccggtgatcc gttccgcggc gagccgtccg gagatcagca ccggcgggat
    10981 gccgacaccc ggcgtcgtcc cgcatccggc gagcaccacg ttttccgccg cccgcaccag
    11041 gttcgccggt cggaacggac cagtttgcgg gaaggtgtgc gcgagcgaga acggggtccc
    11101 ggcggccaac ccgcgcgcgg cccagtcggc cggagtcagc tgttcgtcca caatgtactc
    11161 gtcacggaac ccggtgagcc cgcgcgattc gagcgtccgc aacagttctt cgcgataagc
    11221 cgggccgacg cgcgcccagt cgatcgggcc ggtgttcagg ttcggggccg gagcgagcac
    11281 ggaaatgatc tcgccgccgt cgcccgcgag tgtcggctcg gtcgcggtcg ggcgcgtgac
    11341 cagcagcgac ggatcactca tcagcttgcc ctcgcggacg atctcggcga aggtgcgctc
    11401 ccacgcctgg ccgaagaaaa tcgtgtggtg gtccagttcc ggccatgaac ggtccgcgtg
    11461 cccgtgcagc acgaacgccg atggcgagta cttcaacggc agcacacgcc gcggacgcgc
    11521 gccgatcagc cggtacgccg ctgaaagttc tgtcgcgagc accacggcgt cacactcaat
    11581 acgctcgccc gagcgcgtgc gtacagcgcg tacgcgggac gacactcgct caagccacgc
    11641 ggcttccgtg ccgaaccgca gttcggcacc agcgcgtgtc gcagcgtcgg acatcgcgcg
    11701 ggcgatcgcg cccatgccgc cgcgcgggta gtagacgccg ccgacagtgt ccatgtacgc
    11761 gatgacgccg tacgcgccga gcgcgcgcgt cggatcgaga cccgcgtaca gcgcttggaa
    11821 ggagaagagc cgccgtacgc gctcgtcgcg caagaagctg gagacgcgcg gccccagccg
    11881 accgaagccg cccagcgccg cgagcttccc gagttccggc cggacaagat ccaggggcga
    11941 atcgaagttc gccccgatga agtggtcctt ctgtgccgcg tacaggtcgg tgagccaccg
    12001 tcgcagccgc cggtagccgt ccgcctcggc cggaccggcg aacgaccgga tctcggcttc
    12061 catcgcctcg ccgtcggtgt gcacggcgag cgtgctgcca tcggcgaaac gagcccggta
    12121 cgccggatcg agcctggtca gcggcactgt gtcggccagc gactcgccga ccgcgtgcag
    12181 tgcttcgtcc accagttccg gcatggtgag cacgctggcc ccggtgtcga ccgcgttcgc
    12241 gccgaagtcc tgctggccgg ctcgtccgcc gggcatcttc tgctgctcca gcagcgtcac
    12301 ccgccgtccc gcgccgagca ggtgcagcgt cgccgagagc ccggccagcc cggcgccgac
    12361 gaccacgacg tggtcggcgg gcccgttcac cgtccgcatc agaacttccg ctgggtagcc
    12421 agacggatca gctcggcgag cgcggacgga gcgggctcgg cgaggtgcgc gcggtcgagc
    12481 gcggcgttcg cggaggcggt cagctcgtcg atccggcgct ccaccgcggc gaccgcgccg
    12541 accgaggtca gcgcctcgcg cacctggtcc acggtgccgt tggtcaggtc ggcggccccg
    12601 atcgcgtcgg cgatcgcctt ggccgcggtg tggtcgccct tctccgcggc gagctgcagg
    12661 ccgagcgcca cgagcagggt gcgtttgccc tcgcgcaggt cgtccccggc gggcttgccg
    12721 gtcaccgacg ggtcgccgaa cacgccgagc aggtcgtcgc gcagctggaa cgccacgccg
    12781 acgtcgccgc cgaactccag cagggtggcg atcagccggt cgtccgcccc ggcgagcgag
    12841 gcgccgaggt gcagcggccg ctggacggtg tacgcggcgg tcttgagccg gtcgatccgc
    12901 agcgcggcct cgggcgaagc gtcgccgacg gcctgcgtgc ggacgtcgag gtactgcccg
    12961 gcgagcacct cggtgcgcat cgcgcgccag gcgggccgag ccgccgcgat cgtctccgcg
    13021 ggcagcgggg cgtcggcgaa catgtcgtcg gcccaggcca gcgccagatc gcccaccagc
    13081 accgcgctgg ccagcccgaa caccgacggc gaaccgagcc agccccggtc ggcgtgcagt
    13141 ttctcggcgg ccacgtgcac ggtcggcctg ccgcggcgcg agtccgagga gtcgatgagg
    13201 tcgtcgtgga tcagcgcgca cgcctggatc agctccaggc tcgccaccgc ctgcagcgcg
    13261 ccctcggcga gcggaccgga cgccgcgccg cccgcgccgc gccagcccca ccaggcgaag
    13321 gtcggccgga tccgcttgcc gccgcccagc acgaaaccgg acagcgcctc gatcccggcc
    13381 gcgacgctcg gctcggtgcg caggatctcg ctccccgccc ggccgaggaa atcggccagc
    13441 gcacgctcca cgtgcgcggg gaggtcggcg tcgaatccgg gcgcgtccat gccctcatcc
    13501 tccgggacga gggcggccgg ggtcacgccg ggcgcccccg gatgtggcgc accagacgcg
    13561 ctcagccgct ccggaacgcg tcaggacgcc cgctcgccgc gaagtactcc gctgcctcgg
    13621 ccggtccgcg cggccggtag ccgggttcga gacagccttc gtaccagtcc ttcgcgaggt
    13681 gccacagcgc gtcgagcccg agcagctcgc ccggactgtc cacacaggac tcggcacagt
    13741 acagccgctg cttgccccgg tcgcccgcga gctgctcggg cgaggccggg aagtaggcga
    13801 cctgcgtgcc gctcggcggc cggtcccgcc gcacgaccag cgcggacggc tccccgcagc
    13861 cgggacagcg cgtcgccacc agcacctcgg gctcgcccga gacgaggtgc gggatcgcga
    13921 acgaatccca agcgcagccg ccccaccaca tggtgtgctc gcccatcacc gcgaacccga
    13981 gcgggaccgc cgcgaacggc gcggccagcg ccacgtgctc gcattcgtcc agccacagcc
    14041 atctcgggtc ggccatccgg tgcaacgcct gtttcgccac cgcgagcgac ccgtgcgcgg
    14101 cgtccgccag ctcgggcgcg gtgggcgggc ggccgcggga ggagaacgcg cggtagacgg
    14161 ccacgcgcac gtcttcgtcc caggccagat cgtcttcact gctcatgggc tcgcctcccc
    14221 gggagggttc gcccactgac ggtacgcgcg tggccaagcc cacccgtcag ctctgccgcg
    14281 cgtcgcggcg agccactacc atttcactcc atgacgtcgg tgatcgaaag gctgcggggg
    14341 gacgggcccg cgttctccgt cgagttcttc ccgccccgcg acgaggccga cgaggccgtc
    14401 ctgtggaagg ccatccgcga gctggaaccg ctggacccgg cgtacatgtc gatcacctac
    14461 ggcgcgggcg gttcgagccg cgacggcacc atccgcagca tcgcccgcgt cgccaccgaa
    14521 accacgctct gcccgatggc ccacctgacg gcggtcgacc attcggtggc cgaactgcgg
    14581 aacgtgatcg gctggtacgc ggcggtcggc gtgcgcaaca tcctcgcgct gcgcggcgac
    14641 ccgcccggcg acgtctacgg cgactgggtt ccgcatcccg agggcctcac ctacgccgag
    14701 gaactggtcg gactggtccg ctcgctcggc gacttctgcg tcggcgtctc ggccttcccg
    14761 tacggccacc cgcgttcggc ggacctggaa tcggacacga agcacctggt ccgcaaattc
    14821 cgcgcgggag ccgatttcgc gatcgcgcag ctgtttttcg aggcggagga cttcctgcgg
    14881 ctgcgcgacc gggtcgccgc cgcgggctgc gacgcgctcg tgctgcccgg catcatgccg
    14941 ctgaccactc tgcgcacgct gcacaccacg atcaagctct ccggcgctcc cgcgtcgcag
    15001 cggctgctgg accggctcga accgttctcc gacgacccca aggcgttccg cgcggcgggg
    15061 atcgactggg tcaccgaact gtgcgagaaa ctgatcgccg aaggcgtgcc cgacctgcac
    15121 ttctacacct tcaaccggtc caaggcgacg cgcgaggtgg tcacccggct cgggctggtg
    15181 cccgcccgca cttactaatc cgaccaaaag caggccgacc cccaccccgc acgtaaccgt
    15241 tgctgcgaag ccattaggcc gtggctgtgg tcggattagc aacgatcggc acagtactct
    15301 gtgggccgcg gccaggtccg gccggtagcg tgccggacat ggcttccacc gaacagagcg
    15361 ttccggagat ctgcgaccgg tacgtcgacg attacgtggc cgtggacccg gtcgcggcca
    15421 ccatgctcgg cgtcgcgggc tacgacgacc agctgaccga ctattcgccc acgggccacg
    15481 acgcccgcgc ggacctggcg cggcgcgcgc tggccgcggt gaccgccgcg gaaccggcgg
    15541 acgcggggga gcgggtcgcg aaggccgtgt tcaccgagcg gatcggtctc gagctggaga
    15601 tccacgacgc gggtctcgac gcggcctcgc tcaacgtgat cgagagcccg gtgcagggcc
    15661 tgcggatggt cttcgacctc atgccgaccg acaccccgga cgactgggcg aacgtcgcgg
    15721 cccggctgcc gaaggtgccc gaggcgctgg ccggggtccg cgcgtcgctg ctggcctcgg
    15781 ccgacaaggg gcgggtttcc gccctgcggc aggtctcgaa ggtcgccgag cagtgcgaaa
    15841 cgtgggccgg actcaaggac ggaccgggct tcttcgccgg catggtcgcc gacgcgggcg
    15901 tggactccct gaagtccgac ctggcctcgg gcgcgcgagc cgcggacgag gcgttcgcgg
    15961 aattcgccgg attcctgcgc gccgaactgg ccccgaaggc cccggtgaag gacgccgtcg
    16021 gcgaggacac ctaccggctg tggtcgcgct acttcatcgg cgcggagctg gacctgcgcg
    16081 aggcgtacga gtggggctgg cacgaattct cccgcctcga aacggaaatg cgcgcggtcg
    16141 cgaaccgcat caagcccggt tcgacgccgg cggaagccgc ggcggtgctc gacgccgacc
    16201 cgcgctaccg catccagggc cgcccgcagt tcgaggcgtg gatgcagcag ctgtccgacg
    16261 acgcgctgaa gtcgttgcgc ggcaagcact tcgacatccc ggaccggctg atggcgctgg
    16321 agtgcaagat cgccccgccc ggcggcggcg tcggcgcgta ctacaccggg ccgagcgagg
    16381 acttcagccg tcccggccgg atgtggtggt cgcttcccgc ggaccgcaac gatttcacga
    16441 cctggcgcga ggtttcgacg gtctaccacg agggcgtccc gggccaccac ttgcagatcg
    16501 cgaccgcggt caaccaggcc gagaccctca cgaagtacca gcggctgatg acgttcatct
    16561 cggcgcacgg cgaaggctgg gcgctgtacg cggaacgcct catggaggag ctgggctacc
    16621 tgtcggacga cggcaacctg ctcggcatgc tgtccgagca gctcttccgc gccgcccgcg
    16681 tcgtggtcga cctcggcatg cacctggaac tggaaatccc ggcgggcacc ggattccacg
    16741 agggcgagcg ctggacgccg gatctgggcc tggagttcat gctgacccgc acgatcaccg
    16801 accacgccca catccacgac gagatcgacc gctacctcgg ctggccgggc caggcccccg
    16861 cgtacaagct gggcgaacgc ctctggctgg ccgcgcgcga cgaggcccgt gcgcggcagg
    16921 ggtcggcgtt cgacatcaag cagttccaca cgaaggccct gcagatgggc ggcatggggc
    16981 tggacaccct gcgcgagcag ctggcgcaac tggactgaga ctgctttccc gggccggtgt
    17041 tccgcaccgg cccgggggtc ttccgcgcat gtttaccgct cagctcatcg aaaccacccg
    17101 gttggacctg ctgccgctgt ccgtctcgca cgccgaggag atggcgtcgg tgctgtcgga
    17161 tccggccctg cacacgtaca tcggcggtgc tcccgactcg gcggcggctc tccgcgcgcg
    17221 ttatcagcgg atgaccgcgg gctcgcccga tccggcggtg tcctggctga actgggtgat
    17281 ccggctgcgc gattccggcc ttgtgggcac tgttcaggcg acggtcagcc gcgctgtcgc
    17341 cgaaatcgcc tgggtggtgg gaactccgtg gcagggccgg ggcatcgcca ccgaagccgc
    17401 gcgcggactt gtcgcgtggc tcgaccagcg accggtggac gagatcatcg cccacatcca
    17461 cccggaaaac cgggcctccg ccgccgtcgc cgccgcgatc gggctctccg ctaccggcga
    17521 atggcaggac ggcgagatcc gctgggccgc aaacccgttg atcgtctccc cggcctctgg
    17581 ttaagctccc gcccgtgcag tggcttctcg tcgtcatccc accaccagcc tcctgagcgg
    17641 ggcagttttc gccgcgtgcg cccgaaccgg gcccgcggcc accggatgac gtcctgaacc
    17701 ggccggcaca cgctgtcccg cgtcgtcgat ttccgattcc ttcgacgcag gagcccactt
    17761 ccgaatgtct gttgccgtac cttcgcgcgc ccgctcgtcg gccgccctag tcctcgccgg
    17821 cgtgctctgg ggaaccggcg gcctgtccgg ctcgcttctc gcccagcaag ccggcctgca
    17881 cccgctcgcc gtcgccacct accgcctgct gatcggcggc gccgcgagcg cggcgtacgt
    17941 cgctctcacc ggcggacttc gccttcccgc caaggaaacc tggcgccgtc tccttctcgt
    18001 cggcgccctc ttcgcgcttt tccaagccag ctacttcgct gccgtcgcgc tcagttcggt
    18061 cagcgtcgcg accatgacca cgatcggcgc cgcacccgtt gtgctcacga tggtctccgc
    18121 ggtgcagcgc cgccgcgcgc cccagctgtg gacgctggtg tccgtcggcg gctccgtcgc
    18181 ggggctcgtg ctgttgcgct ggtcgccgga gaccgcgacg tcacccgctc ggcttgtcgg
    18241 cggcctaggc ttcgcgctgc tcgcggcgac cggtttcgcc gtgctcacgc tcgtcacagc
    18301 ggagcccgtc aatggcctag aaccgttggc taccaccgca ttcggctgcc tgaccggcgg
    18361 tttgctgctg acacccgccg cactctggct cggcatgagc ctgcccgcca acgccgacgt
    18421 actgctgttg gcggtgtact tcggcgttgt cccgacagcc gtcgcgtacg ccgcgtactt
    18481 ccgcggtctc ggcggtgccc acccggtgct gggcgcactg tccgcgctgc tggaaccgct
    18541 taccgggacg gtgctttcgg tagttttcct gcacgagcgc ctgagcacgt tcgcgtgggg
    18601 cggcgcggtg ctgctcgtcg cggcactcgc ggtcggctac tggcgacctg agccccggtg
    18661 agcatcattc acggactgtc cgcattcttg gagatttcgc cacgaacggg tggcagattc
    18721 cgctacggtg ccgcgcatga tcaccgaaaa ccgaatattc cgggcagcgg cgctggcagc
    18781 gggggcgact ctgctcgccg ccctcgcggg ctgtggcggc tcgaccgcgg gtaccgccgc
    18841 cgcgggttct cccgcctccg aagcgaaacc cccgatcacc gaccccgccg tccaggcggc
    18901 ggccctgcga acagtggatc cgtgcgcgct gctggacgcc aagactctcg gcgccctcgg
    18961 cactccggac cagtcgagcc tttcgtcctc cgaatggggc gagtgcagcg tcaacgtcaa
    19021 ggactccggc ggcaagaccg tcgaactggt gctgcgcgtc ggcgaccagc tgatcatgtc
    19081 gaaggacccg gccgagaagc tcgaaggcct tccgctggtc gtcgacaacg acaagccagg
    19141 gtcgtgctgg gtctctgtcg tgacgtcgtt cgagcagtct ctggggatca ccttccaggc
    19201 caaggctccg ggcggcgacg cgtgcgcgct cggccgcgcg gcgctggcca aggtcgtgca
    19261 ggccctgcac agcactccgc cgcagtacca gcagatgccc ggttccgtgc tgacgaccga
    19321 cccgtgtgcc gtcgccggca agcaggccgt ggagaccgcg ctggggcaga agtcctttgt
    19381 ggagcccaag agcctgcacg aatgcgactt ctggtccggc gacgacaccc actacccgca
    19441 ggtttcggtg cacctgtacc aaggcctgcc cgccgacgcc gaagacggcc agcccgccga
    19501 cctcggcagc ggcgtcacgg ccatccagaa gaaggacgaa gacagcagcg tagtcagctg
    19561 cgacgcgacc tggcgcaaga tcgaaacccc gaaggacgac gaggcgcacg ggtacggcga
    19621 gatcgtctcc gtgcagttca gcggcgagcc cgccagcgga ctcgacaccg gcaccgcctg
    19681 tacgaaggcg gtcgccgtgg ccaagacagt ggcgccgtcg ctcggccgcg cctgatcgcc
    19741 cgcgatttgc cggtgcgcgg gccttctggg ggccgtgtta tgcggtaggc gagcgcgccg
    19801 cgcgcccggt ccgaaaccgg gcgcgcggcg gtcctaccgc gcttcgagcg gcagcgcccg
    19861 ccccaaaatc gcgaacggcc gcggatcgcc ggtgaactgg tagtcgcgca gaacgtcgac
    19921 gaaccccatg cgccggtaca gcttccacgc ccggctggtc ccctccggag tggagagcag
    19981 cacgttcgcg ctgggcacgc cgtcgagcag cctgcgcagc aggtcctcgc cgatctgctt
    20041 gccctggttc tccgggcgca cgtggatctc ggtgagctcg aagtagtccg ccagccagcg
    20101 ctcggcttcc tcggtcccgg aacggcgggt caggccgtgc cggacctgct cgtgccacca
    20161 ctgcccggcg cggcccttgt agccgtacgc gatgccgagc aggacaccgt tgtcgtcgag
    20221 ggcggctatg cagcgccaac cctcgcgcag cgcgtgcgtg agccacatcg gcgcgcgctg
    20281 ctcggccgtg ccctcggggt agcgcatggc gttcacgtag atcgccagcg cttccggcag
    20341 ccgggaccgg aactcgtcgg cggagagctg cacgtaccgg gagcacccgg aggaggacat
    20401 cgcggtcaca gtcgaccatc ctccccttcg cccgcgagat cgcccggggt gcccccggtg
    20461 agcgtgacga gcgcgtcgaa cgtcgtcggg aagaccgatt tcggatgccc cgccgcggcc
    20521 cacacctcgg cgtacccgcg caacgccgtg tccacgagcg tcacgagccg ctccggatgc
    20581 ccgatcggcg cgacaccccc gatcggctgc ccagtgtgct cccggacgaa cgccgcgtcc
    20641 gccttgccga cttccgcgac cccggcgagt tccgccagcc ggaactcctc ggcccgatgc
    20701 gcccccgaag taagggcgag caacgcgacc tccgccccgt cattcctgcg ggcgcggaaa
    20761 accagactgt tcgcgatagc gccgaccggc acgccgagcg cctccgcggc ctgcgcggcg
    20821 gtgcgcgctt cagcgggcag cacccgcact ccgtcagcgg cggcgtgcag cccggcctcg
    20881 cccagcgcgg cggtgacctt ggcgacagcg ggatggtcgt gggtgctcac tccgttatga
    20941 gaccacgccg gtgcagccgt gtcccgcacc acgtgcccgg attccaccag cggggttgag
    21001 cggattgccc ggcgcggcta ctctggaaac agatcgaaca gacgttcgat acccggtggg
    21061 agcgcaccgg ccggtcccgg ggtgggggaa gcacctcggg cccccggccg ggcccacccg
    21121 agcaggagga gggtcgccat gtccgtctcg gtcgtgtccc ccgcggacag tgccgccgag
    21181 gcaccccgac ctggtgcggt gggcgaacag ctgacgttcg gcgcaccggt ggaacggccg
    21241 ggtgctgctg gtgcttctgc tgctggcggc gctgctcagg cgccgggtgc tggttctgcc
    21301 gcgtcggttc cgtcgcctgc ttcggcggct ggctccgctc agcccgggct cgatctttgg
    21361 ctcgcgtcgg agagcggttc tgccgccggc tccgcccagt ccggtgctgc ggaatctggc
    21421 ccaagcctgt cgcccgcgcc gggaagcggc tcggcggctg actctgctca gtctcctgcc
    21481 gtggaatccg gcctcggttc ctcgcccgag ccggtgccct ccgcttcggc agtcaaccct
    21541 gccgctccgg cgaccaaccc cgcgctgccc ttcgcgtcgg agaacacccc ggccgcggct
    21601 ccccagcccg aacgcgcccc aacccccaag ccaaccgtgc accacgtccc cgaagccccc
    21661 gtgcccagcg gtccgccccc gaggcaggtc gtccaccgca cccgggcagc ggtccggccc
    21721 tctgccgaac cgtccgcccg ccgctccggc gccaagggcc agccgcagct tccgctgtcc
    21781 ctgcgcccgc cggcccctcc cgaggcagtc gccctcctcg cccaggccaa ccgcggactc
    21841 gaccacgcgg aaaacgaacg cgacccagcc gaacgcttca tcggcgccta cctcgccgcc
    21901 ctgcgcggcg ccggtgcggt gctcgccgtc cggggccgtc cgcgccgggg caggggccgt
    21961 ccggccagcg gctgggtgct gctcgacgcc gtcgcccccg aactgcgcga gtggtcggcg
    22021 ttcttcgccg accactccga aacccgggcc gccgccgaag cgggcatcag cggtcgcgtc
    22081 accgccgaac tcgccacggg cctgcttgag gcgaccgccc agttcctcga actcgtccgc
    22141 cgggtcgtgc acggcctgcc gatgaccggg gaagcccatg tcgcgtgaac tcggcacggt
    22201 cgaccacggc cggctgctcg aggcgttctc cgtggaggcg cacctgctgg gggaggtggc
    22261 gcactcggcg tcacccgatt cgccggtgcc caccgccccc ggctggacgt tgaacgagct
    22321 gctcaaacac gtcggctccg tctactggca ggtactcggc tggatccgcg aaggccgccg
    22381 gccagaaccg tggcgcgagc ccctgcccgg ccagccagtg gcggacttct actccgcggc
    22441 ccgcaccgaa ctcgaagccg cactggccga ccacgacccg gccacccgag ccgccacctg
    22501 gtggtccgcc gatccgaccc acggtttctg gcgtcgccgc atgctccacg aaaccctcgt
    22561 gcaccgagtg gacgccgaaa acgcagccgg aaccggcgac tcgacagtgc ccgacgacct
    22621 ggccgccgac ggcgtcgacg aggccctcac cctctacttc ggacacaaac tcaccaccat
    22681 gggcgtctcg ggaacccgaa acggcacagt gggtttccac accggcggcc acagctggat
    22741 cgcgagagca ggccccggcg agacagaggc ctggcgctgc tcttcccgag aagccgacgc
    22801 cgcggacgcg atcgtcaccg gctcgcccgc gaacgtgtac ctctggctct ggggaagagt
    22861 cccggtgacc atggtccaca ccgacggaga ccacgagctg tccgcccaag cctgggccct
    22921 gctgcgactg gcgaccagat agcgttcgag aaccgaaagc ggggaagctt cccggttctg
    22981 cgctgtttcc agaccaccgt ggcgatccgg ctgtgccggc aagcgtgata cccccgcgct
    23041 tgccggcaca gttctttcac ccgatcccgc acccgctgcg ccgccgcgac ccgccgtttt
    23101 cgtcggccct gcccgctacc gtggcgacat ggcaccacgt ctggccaacc tggtcatcgc
    23161 cgccgaacag ccagcacgcc tggcccgctt ctggtccggc ctcctaggct ggcagctcac
    23221 cacggaatcc ccggacgagg ccaccgtcca acccgcaccc gacgacggct gcgatctcac
    23281 cctgctcttc gccgcgacct cccgcccgaa gaccgccaaa aaccggctcc acttggacct
    23341 ctccagcacc tccggcgaaa accagcgcga aacggtagcc cgagcggttt ccctgggcgc
    23401 acgccccatc gacatcggcc agcaccacgt cccgtggatc gttctggccg accccgaaga
    23461 caacgagttc tgtgtgctgg aaccccgcgc
//
