LOCUS       NZ_AP025344            22607 bp    DNA     circular CON 24-MAR-2024
DEFINITION  Paenibacillus dendritiformis strain J27TS7 chromosome, complete
            genome.
ACCESSION   NZ_AP025344
VERSION     NZ_AP025344.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus dendritiformis
  ORGANISM  Paenibacillus dendritiformis
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1
  AUTHORS   Okumura,K., Okamoto,M. and Takamatsu,D.
  TITLE     Whole-Genome Sequences of Bacillus and Paenibacillus sp. Strains
            Isolated from Honey in Japan
  JOURNAL   Microbiol Resour Announc 11 (11), e0084222 (2022)
   PUBMED   36301092
  REMARK    DOI:10.1128/mra.00842-22
REFERENCE   2  (bases 1 to 6547390)
  AUTHORS   Takamatsu,D., Mada,T., Okumura,K. and Okamoto,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-DEC-2021) Contact:Daisuke Takamatsu National Institute
            of Animal Health,NARO; Kannondai3-1-5, Tsukuba, Ibaraki 305-0856,
            Japan
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Coverage                   :: 124x
            Sequencing Technology             :: PacBio; NovaSeq 6000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021654795.1-RS_2024_03_24
            Annotation Date                   :: 03/24/2024 09:12:59
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,875
            CDSs (total)                      :: 5,765
            Genes (coding)                    :: 5,679
            CDSs (with protein)               :: 5,679
            Genes (RNA)                       :: 110
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 82
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 86
            CDSs (without protein)            :: 86
            Pseudo Genes (ambiguous residues) :: 0 of 86
            Pseudo Genes (frameshifted)       :: 39 of 86
            Pseudo Genes (incomplete)         :: 62 of 86
            Pseudo Genes (internal stop)      :: 15 of 86
            Pseudo Genes (multiple problems)  :: 26 of 86
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:45:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2702980
            Orig. end                         :: 2725587
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            AP025344.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated by DFAST https://dfast.ddbj.nig.ac.jp/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22607
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="8"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22607
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22607
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12607](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12607
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            34..294
                     /db_xref="GeneID:73384910"
                     /locus_tag="L6439_RS11870"
                     /old_locus_tag="PsJ27TS7_23890"
     CDS             34..294
                     /codon_start=1
                     /db_xref="GeneID:73384910"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L6439_RS11870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PsJ27TS7_23890"
                     /product="hypothetical protein"
                     /protein_id="WP_213471229.1"
                     /transl_table=11
                     /translation="MEVNMLYHQYMKPNSEYYEKMSAIEEAYEVNEIPDTYAVISDIDS
                     VWKHYHVKGLTQPEQGWKIHVTATLEDSQGVLEKVARLCIR"
     gene            341..964
                     /db_xref="GeneID:73384911"
                     /locus_tag="L6439_RS11875"
                     /old_locus_tag="PsJ27TS7_23900"
     CDS             341..964
                     /codon_start=1
                     /db_xref="GeneID:73384911"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L6439_RS11875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PsJ27TS7_23900"
                     /product="hypothetical protein"
                     /protein_id="WP_213471228.1"
                     /transl_table=11
                     /translation="MNSKNANRASSGKFITIYPINNESFVDLLELISSTIRDFQKGPYI
                     LNDKRWKNSNVFYGFKHIINEHAEHCIRDDQGNLIKDQRTPFPFYQVPDFVKDFDDYLN
                     TINNDLEKKEEGNLEKYEIETALAYSNAGGVYRATRKKNNVKVIIKEARPNAGLDGAGQ
                     DALARQKIEYDALKKLKDVPGVVNLIGYFQEWEHYFIEKRWMRF"
     misc_feature    complement(1102..1116)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 25.44"
                     /tool="antismash"
     gene            1542..2384
                     /db_xref="GeneID:73384912"
                     /locus_tag="L6439_RS11880"
                     /old_locus_tag="PsJ27TS7_23920"
     CDS             1542..2384
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384912"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024880.4"
                     /locus_tag="L6439_RS11880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_23920"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_213471227.1"
                     /transl_table=11
                     /translation="MIHIEKLLGIAKHPEPFEEGTQEIWLDPDRSDLVLKSHFDEDIPG
                     GSRESSFIDETIDFISNLAPVEKYKKVIDLGCGPGLYSQRLAMRGYDVVGVDFNKNSIE
                     YATSEAKEKNLSIDYRNEDITNIELEPDFDLALLIYQIYGVFNPANRKKILSNIHRGLK
                     PGGLVLLDVLSETSYEKFEPNFMWMLSDEGSLLSDKSHLILYAALKYPNKVTLARNILV
                     FDDGKLVNYNYWNQNFSIEDLEKEVDEAGFTLEKVYADVNGGEYVNNSESFAAVLKKK"
     gene            2558..4318
                     /db_xref="GeneID:73384913"
                     /locus_tag="L6439_RS11885"
                     /old_locus_tag="PsJ27TS7_23930"
     CDS             2558..4318
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384913"
                     /gene_functions="resistance (resist) ABC_efflux"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004231816.1"
                     /locus_tag="L6439_RS11885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_23930"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_213471226.1"
                     /transl_table=11
                     /translation="MKRLTLKQFIGILDKYRPSGWLLFIAVVLSIIQTGISLIIPLVSM
                     ELVDLLVVEEFNIFTLLGLLLLFMFQVSLSGISLYMMIYIGEGIIVRLREDLWRRVVRF
                     PVKFFDANNSGEIMSRITNDTMVMKNFFVDHLIPFFTGLITITGSLIILFLIDWKMALI
                     FLLVFPAAFLVLNPLGKKMYRVSKDMQNETALFQGNLSRVLSDVRLVKLSVAENEEAVQ
                     GAKRARRLYKFGLESGKVIAVVSPLITTTLLIVLVVIFGCGGYQVATGSLSAGALVAIV
                     YYMFQIMTPVTLMAQFFTQAQKAMGATERVNSLLVEELEEVVIPNKENVKEDIEDGITF
                     SNVVFSYSEEGGVLNNISFTAKEGKKTAIVGESGVGKTTLFSLLERFYIVDSGDIFYNG
                     RSIYSHELSKWREKIAYVSQDTPIMEGSIKDNLVYGIKKDISDSIIFDALKSANLDSFV
                     SSLPQGLDTEVGEKGIRLSGGQKQRIAIARAIIRDPKILLLDEATAHLDSQSEALVQEA
                     FNNLMRDRTTIIIAHRLSTIKDADCIVVIQEGKVSGCGSHYELYETNQLYKTLFNQQTF
                     SKELVLSGNV"
     gene            4392..4526
                     /db_xref="GeneID:73384914"
                     /locus_tag="L6439_RS11890"
                     /old_locus_tag="PsJ27TS7_23940"
     CDS             4392..4526
                     /codon_start=1
                     /db_xref="GeneID:73384914"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="L6439_RS11890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_23940"
                     /product="class III lanthipeptide"
                     /protein_id="WP_206106325.1"
                     /transl_table=11
                     /translation="MNTVLELQELAHDTDGKGQAAEATVISTIAATTCVTTTVITAGK"
     CDS_motif       4392..4457
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNTVLELQELAHDTDGKGQAAE"
                     /locus_tag="L6439_RS11890_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4458..4526
                     /prepeptide="core"
                     /locus_tag="L6439_RS11890_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="4.30"
                     /molecular_weight="1961.3"
                     /monoisotopic_mass="1960.2"
                     /core_sequence="ATVISTIAATTCVTTTVITAGK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNTVLELQELAHDTDGKGQAAE"
                     /leader_location="[4391:4457](+)"
                     /alternative_weights="1979.3"
                     /alternative_weights="1997.3"
                     /alternative_weights="2015.3"
                     /alternative_weights="2033.4"
                     /alternative_weights="2051.4"
                     /alternative_weights="2069.4"
                     /alternative_weights="2087.4"
                     /alternative_weights="2105.4"
     misc_feature    complement(4887..4902)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 22.96"
                     /tool="antismash"
     gene            5023..5874
                     /db_xref="GeneID:73384915"
                     /locus_tag="L6439_RS11895"
                     /old_locus_tag="PsJ27TS7_23960"
     CDS             5023..5874
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384915"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016718230.1"
                     /locus_tag="L6439_RS11895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_23960"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_213471239.1"
                     /transl_table=11
                     /translation="MSYLLEIKNISKSFGDKIVLKDVTFNVPSGSIVGFIGDNGAGKST
                     TFKTVLGLISKDSGTVKVLGEENIHKNAKIKEKIGVVFDAMNLPAHLTIKQLNKVFKRL
                     FDLWDQENFYRLVHSFSLPLDKKVHTFSRGMSMKLSVAVALSHNAKLLLLDEATGGLDP
                     SSREELLEELEKFVRKSNGGILLSSHIMSDVEKIASHIVIIKDGEILLNEEKDKVFESY
                     AIVDIDDEQLKLLNKDIVVAKRNHGSYFSVLVSDRQGLPNGIVSKTISMEEMSVLLTRS
                     EK"
     gene            5874..6503
                     /db_xref="GeneID:73384916"
                     /locus_tag="L6439_RS11900"
     CDS             5874..6503
                     /codon_start=1
                     /db_xref="GeneID:73384916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214697.1"
                     /locus_tag="L6439_RS11900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC-2 transporter permease"
                     /protein_id="WP_213471225.1"
                     /transl_table=11
                     /translation="MRGLLLTNYYLVYRSIFAYTGLAILVSGIILYFGGASMRGIAALL
                     IILLMAVPSLEVIKSESKSGYDKYVLTLPVRRSNIVQSHYFFYFSVAFIGSLLSYVILY
                     VSNLMSDTPSTGIFNTVSIGTFIVLFVGALVYPFLYIFGPEKSDGIIIGSGFVAVFATF
                     GLRNLVDQIPNINPSLYVPVIYIIFGVIIYVLSYFISVFIYHKKEF"
     gene            6763..8042
                     /db_xref="GeneID:73384917"
                     /locus_tag="L6439_RS11905"
                     /old_locus_tag="PsJ27TS7_23990"
                     /pseudo=""
     CDS             6763..8042
                     /codon_start=1
                     /db_xref="GeneID:73384917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005808317.1"
                     /locus_tag="L6439_RS11905"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="PsJ27TS7_23990"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIDHQTDLKQLPNEIKPAFQELNVLKHLQQAGFRKRFGFSCALLF
                     QLVFVLLFHQRNWFRLLESSKGDSMPGKDAVYRFLNYAGCCAWRRFLTSLSVATVQKVN
                     ALTSADRDTVFIIDDSMFERNRSKAFELLARFKEHATGAYYKGFRMLTMGWSDGHTFLP
                     IDFPLLSSSKSSINGMSESIDKRTHGYKRRQESLLSAPAVSALMLDRALTAGATASYVL
                     MYSWSTHAPLIGEVVARGLDVIGMVDNKRFLIQGQKLSIQELYAVAPPVVSKKRSNLRS
                     IQTELPSGIPVRFVFVRHRSRKNEWLAILATDLTLTVEDFIRIYAIRWDIEVFFKCTKS
                     LLRLRWNFKAVPTSC"
     gene            8154..9449
                     /db_xref="GeneID:73384918"
                     /locus_tag="L6439_RS11910"
                     /old_locus_tag="PsJ27TS7_24010"
     CDS             8154..9449
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384918"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002150929.1"
                     /locus_tag="L6439_RS11910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24010"
                     /product="pitrilysin family protein"
                     /protein_id="WP_237096830.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 7.1e-24,
                     bitscore: 83.2, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNVFDLDEVAIRSSEQNGLHLHLCSTDKFKTMNIMLTMKSPLQ
                     KDLITARALIPHILNGGSKNYPNHKRIKQKLDEMYGATLFPNVQKEGDNHTISFRMEIP
                     AVQYLNVTNTFMKSAFDLLHDIVYSPVLENGVFNSTIVEQEKRSLKQRFASMYSEKMLY
                     ASVRLIEEMFEGEPYQLSAYGIEEDIDSLNDASIYQIYKDLLQNDRFDLYIVGAFNEDE
                     VTLMVHDVFSEEHKDKPVNTISPARKDRNGIKIIQDKQDVNQGKLLLGYRTYSTIQDED
                     FEATRLANAIFGRFPSSKLFMNVREKKSLAYFAQSQLESNKGLLVTMAGIDFDNYERAV
                     EIIREQEYAMKEGNFTEDEVEQGKAMLINLLLEAYDVPLGIMEIAIEAVDRGFSSNLVD
                     QINRINRVTKSELIRAANKWELDTIYFLNRKD"
     misc_feature    9455..9475
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.24"
                     /tool="antismash"
     misc_feature    complement(9636..9648)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.71"
                     /tool="antismash"
     gene            10001..12607
                     /db_xref="GeneID:73384919"
                     /gene="lanKC"
                     /locus_tag="L6439_RS11915"
                     /old_locus_tag="PsJ27TS7_24020"
     CDS             10001..12607
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384919"
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="L6439_RS11915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24020"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_213471224.1"
                     /sec_met_domain="micKC (E-value: 4e-141, bitscore: 470.1,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 6.6e-19, bitscore: 66.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-15, bitscore:
                     54.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEGNMLYHQYLKPNSEYYEKMSATVKAYEVNEIPDTYAVISDNDS
                     VWKHYHVKGLTLPEQGWKIHVTATLEDSQGVLEKVSRLCIDRKIDFKHLKDRNSFLEMN
                     SKNANRASSGKFITIYPLNNESFVDLLELISSTVRDFQKGPYILNDKRWKNSNVFYRYG
                     GFKSIINEHGEHCIRDNQGNLIKDQRTPFYQVPDFVKDFDDYLNTINNDLETKADGNLE
                     KYEIETALTYSNAGGVYLATRKKDNMKVIIKEARPKAGLDGVGQDALSRQKIEYDALKK
                     LKDVPGVVNLIEYFQEWEHCFLVEEFIEGQDLRQWMARDFPFIKDSDRLRDHAEKVKKI
                     LLQLFSLIHNIHKNGVAMGDLQPSNVMVTEDLTVRIIDFETAMPVSSEDNPSMATTGFV
                     SREMKVSGARDWFGLKKIILFLALPVLSSEDLEGYLQSNHFNWIKENYGDSFYRFIVDL
                     QEKCNKRINDYQKYTPKEINLCDQPSDFNISSIIDKLIKGIENNLTNDERFINGDIRQF
                     MMSGAKFNFLTGGSGAAFTLTKKQSKTVEVDQWIQSFLLDNLDRIEDNGLLTGKTGILA
                     LLYEKGYKEVVFNEMKVLKDNINETNISLRSGLSGIGLFVISLYLETENKEYLQFAKEI
                     EELIECNRVKGEPLRVSDWMAVNIGAIDGLSGVALFYSALYSATNNKKYLKKAELLLKE
                     DLESTKKDDASGVLQTLDKRNRLLPYLSGGSIGIAISIWFLNHVSGQDLYKEEMDAILK
                     LSKICCTISGSLFDGAGSFLLIPSMVERSKKREKMVSEVLELLNIFLIEKNGYYVYPGQ
                     FSFRLADDVYTGSSGIILALMGVVKDNPLYWLPLINSDQFLERTKAKVLAVSGEQV"
     gene            12765..12911
                     /db_xref="GeneID:73384920"
                     /locus_tag="L6439_RS11920"
                     /old_locus_tag="PsJ27TS7_24030"
     CDS             12765..12911
                     /codon_start=1
                     /db_xref="GeneID:73384920"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="L6439_RS11920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24030"
                     /product="class III lanthipeptide"
                     /protein_id="WP_213471222.1"
                     /transl_table=11
                     /translation="MNTVLELQKLAHDTDGKGQAVDATPTTVTVTTVTTTVAGWSTQSQ
                     HHC"
     CDS_motif       12765..12830
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNTVLELQKLAHDTDGKGQAVD"
                     /locus_tag="L6439_RS11920_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12831..12911
                     /prepeptide="core"
                     /locus_tag="L6439_RS11920_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-0.30"
                     /molecular_weight="2499.7"
                     /monoisotopic_mass="2498.3"
                     /core_sequence="ATPTTVTVTTVTTTVAGWSTQSQHHC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNTVLELQKLAHDTDGKGQAVD"
                     /leader_location="[12764:12830](+)"
                     /alternative_weights="2517.7"
                     /alternative_weights="2535.7"
                     /alternative_weights="2553.8"
                     /alternative_weights="2571.8"
                     /alternative_weights="2589.8"
                     /alternative_weights="2607.8"
                     /alternative_weights="2625.8"
                     /alternative_weights="2643.9"
                     /alternative_weights="2661.9"
                     /alternative_weights="2679.9"
                     /alternative_weights="2697.9"
     gene            12964..13089
                     /db_xref="GeneID:73384921"
                     /locus_tag="L6439_RS11925"
                     /old_locus_tag="PsJ27TS7_24040"
     CDS             12964..13089
                     /codon_start=1
                     /db_xref="GeneID:73384921"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="L6439_RS11925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24040"
                     /product="class III lanthipeptide"
                     /protein_id="WP_213471223.1"
                     /transl_table=11
                     /translation="MNAVLELQKLAHDTDGKGQAADATPILTTPTRWSTQSQHHC"
     CDS_motif       12964..13029
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNAVLELQKLAHDTDGKGQAAD"
                     /locus_tag="L6439_RS11925_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13030..13089
                     /prepeptide="core"
                     /locus_tag="L6439_RS11925_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="4.30"
                     /molecular_weight="2039.2"
                     /monoisotopic_mass="2038.0"
                     /core_sequence="ATPILTTPTRWSTQSQHHC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNAVLELQKLAHDTDGKGQAAD"
                     /leader_location="[12963:13029](+)"
                     /alternative_weights="2057.3"
                     /alternative_weights="2075.3"
                     /alternative_weights="2093.3"
                     /alternative_weights="2111.3"
                     /alternative_weights="2129.3"
                     /alternative_weights="2147.4"
     gene            13142..13288
                     /db_xref="GeneID:73384922"
                     /locus_tag="L6439_RS11930"
                     /old_locus_tag="PsJ27TS7_24050"
     CDS             13142..13288
                     /codon_start=1
                     /db_xref="GeneID:73384922"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038154.3"
                     /locus_tag="L6439_RS11930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24050"
                     /product="class III lanthipeptide"
                     /protein_id="WP_213471222.1"
                     /transl_table=11
                     /translation="MNTVLELQKLAHDTDGKGQAVDATPTTVTVTTVTTTVAGWSTQSQ
                     HHC"
     CDS_motif       13142..13207
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNTVLELQKLAHDTDGKGQAVD"
                     /locus_tag="L6439_RS11930_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       13208..13288
                     /prepeptide="core"
                     /locus_tag="L6439_RS11930_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-0.30"
                     /molecular_weight="2499.7"
                     /monoisotopic_mass="2498.3"
                     /core_sequence="ATPTTVTVTTVTTTVAGWSTQSQHHC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNTVLELQKLAHDTDGKGQAVD"
                     /leader_location="[13141:13207](+)"
                     /alternative_weights="2517.7"
                     /alternative_weights="2535.7"
                     /alternative_weights="2553.8"
                     /alternative_weights="2571.8"
                     /alternative_weights="2589.8"
                     /alternative_weights="2607.8"
                     /alternative_weights="2625.8"
                     /alternative_weights="2643.9"
                     /alternative_weights="2661.9"
                     /alternative_weights="2679.9"
                     /alternative_weights="2697.9"
     gene            complement(<13587..13814)
                     /db_xref="GeneID:73384923"
                     /locus_tag="L6439_RS11935"
                     /pseudo=""
     CDS             complement(<13587..13814)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384923"
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /locus_tag="L6439_RS11935"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVTPQSLQRQAVEGTNVTRDITCQWGIEQGRSEKRRTFSGSEIRV
                     ATSLLHVSAEQIATIYKARWSIEVFFRWIKQ"
     gene            complement(13848..13979)
                     /db_xref="GeneID:77101191"
                     /locus_tag="L6439_RS29300"
                     /old_locus_tag="PsJ27TS7_24060"
     CDS             complement(13848..13979)
                     /codon_start=1
                     /db_xref="GeneID:77101191"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L6439_RS29300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PsJ27TS7_24060"
                     /product="hypothetical protein"
                     /protein_id="WP_269155985.1"
                     /transl_table=11
                     /translation="MKVTKTVTIKHDGPIGEKLANPDYIMVEDRAYGKIERFDTHEK"
     misc_feature    complement(14166..14181)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.28"
                     /tool="antismash"
     gene            complement(14367..15484)
                     /db_xref="GeneID:73384924"
                     /locus_tag="L6439_RS11940"
                     /pseudo=""
     CDS             complement(14367..15484)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012032558.1"
                     /locus_tag="L6439_RS11940"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTQYQITLDSQLLHQLFLSESRDAGIAAY"
     gene            15758..15901
                     /db_xref="GeneID:73384925"
                     /locus_tag="L6439_RS11945"
                     /old_locus_tag="PsJ27TS7_24090"
     CDS             15758..15901
                     /codon_start=1
                     /db_xref="GeneID:73384925"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L6439_RS11945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PsJ27TS7_24090"
                     /product="hypothetical protein"
                     /protein_id="WP_237096831.1"
                     /transl_table=11
                     /translation="MGKHFSREKRRQIVKEAMAGIKVGTLARMYGVHPDLEKAAWKGCS
                     LF"
     gene            16052..16333
                     /db_xref="GeneID:73384926"
                     /locus_tag="L6439_RS11950"
                     /old_locus_tag="PsJ27TS7_24100"
     CDS             16052..16333
                     /codon_start=1
                     /db_xref="GeneID:73384926"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L6439_RS11950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PsJ27TS7_24100"
                     /product="hypothetical protein"
                     /protein_id="WP_213471240.1"
                     /transl_table=11
                     /translation="MKKFIFRSSFIIDCGMRQWQGRFAPTAYPSKYAEKNGHIVVAPSG
                     LKNAEKMEEFLAKHNDREKAALRMRCIRLKGMPFFMMCIQTERRFNIQ"
     gene            17045..17938
                     /db_xref="GeneID:73384927"
                     /gene="prpB"
                     /locus_tag="L6439_RS11955"
                     /old_locus_tag="PsJ27TS7_24120"
     CDS             17045..17938
                     /EC_number="4.1.3.30"
                     /GO_function="GO:0046421 - methylisocitrate lyase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019629 - propionate catabolic process,
                     2-methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384927"
                     /gene="prpB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonatesMeIsocitrateLyase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006674614.1"
                     /locus_tag="L6439_RS11955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24120"
                     /product="methylisocitrate lyase"
                     /protein_id="WP_168178085.1"
                     /sec_met_domain="phosphonatesMeIsocitrateLyase (E-value:
                     6.3e-131, bitscore: 434.1, seeds: 9, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.8e-49, bitscore:
                     166.8, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRLDSPGLRLRQAVEEERPLQVAGTINAYAAMLAKSAGFRAIYL
                     SGAGVANASFGLPDLGITTLNDVTEDVRRITSAVDLPLLVDADTGFGSAFNIARTIREM
                     TRAGAAGVHIEDQAMAKRCGHRPNKAIVSKDEMADRIKTAVDARTDGSFVVMARTDALA
                     SEGLDAAIERAAAYVEAGADMIFAEAVTEVWQYRKFAEAVNVPILANITEFGQTPMLSV
                     EELGAAGVSLVLYPLSAFRAMNAAALQVYQTIRREGTQKSVIDMMQTRNDLYEYLKYHE
                     YEKKLDELFAAGKEGQ"
     gene            17939..19063
                     /db_xref="GeneID:73384928"
                     /gene="prpC"
                     /locus_tag="L6439_RS11960"
                     /old_locus_tag="PsJ27TS7_24130"
     CDS             17939..19063
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /GO_function="GO:0050440 - 2-methylcitrate synthase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384928"
                     /gene="prpC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006674613.1"
                     /locus_tag="L6439_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24130"
                     /product="2-methylcitrate synthase"
                     /protein_id="WP_213471219.1"
                     /transl_table=11
                     /translation="MTTAKKQGGLAGIIAGQTAIATVGKEGKGLNYRGYSIYDLAEHAT
                     FEETAYLLVYGTLPSFSELSAYRSKLQRLRGLPAGLKRVLEQLPAGSHPMDVLRTGCSV
                     LGTMEPEGPGRSHSDIADRLMASFGSMLLYWHHYAQTGARIETETDDSSIAGHFLHLLH
                     GKKPEPLHERAMDVSLILYAEHEYNASTFASRTAASTLSDMYSAITSGIGTLRGPLHGG
                     ANEAAMELIQQFRTPDEAEAGLRRMLQEKKRIMGFGHRVYSVSDPRSDVIKVWSRRLSE
                     HAGNMKLYRISERIESVMREEKKLFPNLDFYSASAYHLMGIPTAMFTPVFVISRTSGWS
                     AHIIEQRANNKLIRPNAEYIGPEPQPWLPMESRT"
     gene            19087..20526
                     /db_xref="GeneID:73384929"
                     /locus_tag="L6439_RS11965"
                     /old_locus_tag="PsJ27TS7_24140"
     CDS             19087..20526
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.79"
                     /GO_function="GO:0047547 - 2-methylcitrate dehydratase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_process="GO:0019679 - propionate metabolic process,
                     methylcitrate cycle [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006674612.1"
                     /locus_tag="L6439_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24140"
                     /product="bifunctional 2-methylcitrate
                     dehydratase/aconitate hydratase"
                     /protein_id="WP_213471218.1"
                     /transl_table=11
                     /translation="MSSHLSNARPDHDQAIKDIAAYVGRAIDSGEAYRTARYCLIDSLG
                     CGMLALRYPECTKLLGPIVPGTVVPNGAKVPGTSYQLDPVTAAFNIGAMIRWLDYNDTW
                     LAAEWGHPSDNLGGILAVADYVSRKNAAEGKAPLLMRDVLTGMIQAHEIQGVIALENSF
                     NRVGLDHVLLVKVASAAVVTKLLGGTEEQIMNAVSNAWIDGQSLRTYRHAPNTGSRKSW
                     AAGDATSRAVRLAMMSLKGEMGCPSALTAKTWGFYDVLFKGSEFKFPRPYRSYVMENVL
                     FKISFPAEFHAQTAVECAIQLHPDVKDRLDDIDHIAIATHESAIRIIDKKGPLHNPADR
                     DHCLQYITAIGLIFGELTADHYEDSTAKDPRIDALREKMIVVENPQYSKDYLDPEKRSI
                     ANAVQVMFKDGSRTDNVAVEYPIGHRRRRAEGIPLLVKKFKNNLETRFPAKQVADILEL
                     CENQERLEATPVHVFVDKFLI"
     gene            21053..21214
                     /db_xref="GeneID:73384930"
                     /locus_tag="L6439_RS11970"
                     /old_locus_tag="PsJ27TS7_24150"
     CDS             21053..21214
                     /codon_start=1
                     /db_xref="GeneID:73384930"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="L6439_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="PsJ27TS7_24150"
                     /product="hypothetical protein"
                     /protein_id="WP_237096832.1"
                     /transl_table=11
                     /translation="MNQEHTAYQWLSFQEAKEIALPGNDEVLEFIEKHFIKKKPSIWLY
                     VGGGTNDV"
     gene            21204..21455
                     /db_xref="GeneID:73384931"
                     /locus_tag="L6439_RS11975"
                     /old_locus_tag="PsJ27TS7_24160"
     CDS             21204..21455
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:73384931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010095628.1"
                     /locus_tag="L6439_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24160"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_237096833.1"
                     /transl_table=11
                     /translation="MMYNRVDVACALIFDQASENVVMVKNKKGDSCYWSLPGGAVEAGE
                     TLEAAVIRETKEEAGFEVEAGGLYSVSEALFSNCQCLH"
     gene            21479..22045
                     /db_xref="GeneID:73384932"
                     /locus_tag="L6439_RS11980"
                     /old_locus_tag="PsJ27TS7_24170"
     CDS             21479..22045
                     /codon_start=1
                     /db_xref="GeneID:73384932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006210888.1"
                     /locus_tag="L6439_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="PsJ27TS7_24170"
                     /product="2-phosphoglycerate kinase"
                     /protein_id="WP_213471217.1"
                     /transl_table=11
                     /translation="MIILISGNSCTGKTLMSQRLLEKYLIPYFSVDHLKMGLYRSDSNC
                     GFTPQDSDEAIGEKLWPIIKGMIMTSIENNQNMIIEGCYILARFIKDFEKPYSENIISV
                     FLGFSTNYIKQNFDSNIVKHRSAIETRLYPEERTISRFIDEHDHFRRSCKEYGVPYFEI
                     DQNYKEEIMKVYDFIEVQKRKMEAN"
     misc_feature    complement(22307..22322)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 22.59"
                     /tool="antismash"
ORIGIN
        1 catcgtggat atacatagag aaagtggata tgtatggaag taaatatgct ttatcatcag
       61 tacatgaaac caaattcaga atattacgaa aaaatgagcg cgatagaaga ggcatatgaa
      121 gtgaatgaga ttcctgatac atatgctgtt atttcagaca ttgactccgt ttggaagcac
      181 tatcatgtta agggattaac acaaccagaa cagggatgga aaattcatgt aactgcgaca
      241 ttagaagatt cacagggtgt gctagaaaaa gttgctcggt tatgcataag atagaaaaat
      301 tgagttcaag catcttaagg atagaaacag ttttattgag atgaattcga aaaatgctaa
      361 tcgtgcttct tctgggaaat ttataacaat ataccctatt aataacgaaa gctttgttga
      421 cttgttagaa ttgatttctt caacaatccg ggattttcaa aaaggacctt atattcttaa
      481 tgataagaga tggaaaaata gcaatgtatt ctatggcttt aaacatataa ttaatgaaca
      541 tgccgaacat tgcattagag atgatcaagg aaatttaatt aaggatcaaa gaactccttt
      601 tcctttttac caggttcctg actttgtaaa ggatttcgat gattatctga ataccattaa
      661 taatgatttg gaaaagaaag aggaaggcaa tttagagaag tatgagattg aaactgcact
      721 ggcctatagt aatgctggtg gggtataccg tgcgacacgc aagaaaaata atgtgaaagt
      781 gattatcaag gaagctagac caaatgcagg tttagatggg gcgggtcaag atgccttagc
      841 taggcaaaaa atcgaatacg atgctttgaa aaaacttaaa gatgtacccg gtgttgtgaa
      901 tttgataggg tatttccaag aatgggagca ttattttata gagaagagat ggatgcgatt
      961 ttaaaattat caaagatttg ttgcacagtt agtggaagct tatttgatgg cgcaggcagc
     1021 tttattttaa tccctcctat ggtcgaacat aggaaaaacc gcgaggaaat tgttagtgat
     1081 gtattgaagt tacttaatct cttttctaat tgagaagaat ggttattatg tatatccagg
     1141 acaatttcct tttagattag ccagggagtt caggaataat tttagcatta atgggggtag
     1201 tcaaagataa tccactctat tagttaccat tgatcaattc ggatcaattt ctagaaagaa
     1261 caaaggccaa ggctctagca gtaactagtg aaaaagtgta acgaaatgtg tggtgcaaaa
     1321 tgagtgtatg acacagatgg taaaggccaa gcagcggaag caacagtcac aacagtaaca
     1381 acgactgtaa ctggtgtgtg tacattaagt gtttggaaat gcaaaaaata attaaataag
     1441 atttaactaa ttgcaaaagt tgaatgccga atttatttgt tgttcaaacc tacccagaac
     1501 tcatttatta tactcataaa tcataaaaat atcaagagag ggtgatacat atcgaaaagt
     1561 tattaggaat agccaaacac cccgagccat ttgaagaggg cacacaagaa atctggcttg
     1621 atccagatag atctgatctt gttttgaagt ctcactttga cgaggatata cctggaggta
     1681 gtagggaaag cagttttatt gatgaaacta ttgattttat tagtaacctt gcaccagtag
     1741 agaaatataa aaaggttatt gacttaggtt gtggtccagg gctttattca caaagattgg
     1801 caatgagggg ctacgatgtt gtaggtgtag attttaacaa aaattccatt gaatacgcaa
     1861 ctagtgaagc taaagaaaag aatttatcaa tagattatag gaatgaagat attactaata
     1921 ttgaactaga acctgatttt gatttagccc ttttaattta tcagatttac ggtgtcttta
     1981 atccagctaa tagaaaaaaa atacttagta atatccaccg tgggttaaaa ccgggaggat
     2041 tagtattatt agacgtgtta tcagagacta gttatgaaaa gttcgaacca aattttatgt
     2101 ggatgttatc tgacgaaggt agcctattat cagataagag ccatttaatt ttatacgccg
     2161 cacttaagta tcctaataaa gttactttgg caagaaacat cctagttttt gatgatggta
     2221 agttagtaaa ttataattat tggaatcaaa atttcagtat tgaagattta gaaaaagaag
     2281 tggatgaagc aggttttact cttgaaaagg tatatgcgga tgttaatggt ggagaatacg
     2341 tgaacaatag cgagtccttc gccgcagttt taaaaaagaa ataatcagat aagtaccagt
     2401 taaggattca gtgtttgcaa gaataggaat aatttatccc ctggctctaa cactgaatcc
     2461 taaagttaaa atgtctaagg ataagaaagt ttcacatatt taatatgtgt ttaaataagt
     2521 cgttcgcaaa taaagataaa aggataaaca taaaaatatg aaaagactca ctttaaaaca
     2581 atttatcggt attctagata agtacagacc ttctgggtgg ttacttttca tagcagttgt
     2641 attatcgata attcaaacgg gcatatcttt aataattcca ttagtttcca tggaacttgt
     2701 cgatttattg gttgttgaag aatttaatat ttttacttta ttaggattgc tgcttctttt
     2761 tatgttccaa gtttcacttt ctggtatttc tctttatatg atgatttata ttggtgaagg
     2821 aataattgtc cgcctaagag aagatttatg gagaagagta gtaagatttc ctgttaaatt
     2881 ttttgatgca aataattcag gagaaataat gagtagaatt acaaatgata cgatggtaat
     2941 gaagaatttc tttgtagatc atttgattcc tttctttaca gggctaatta cgattacagg
     3001 ttctcttatc attctttttc taatagattg gaagatggcg cttatttttt tactagtttt
     3061 tcctgctgca tttttggttc taaacccact tggtaaaaag atgtacaggg tttccaaaga
     3121 tatgcaaaat gaaacagcct tatttcaagg aaatcttagc agggtattaa gtgatgttcg
     3181 tttagtaaag ctttcagttg ctgaaaatga agaagctgtt caaggggcta agcgtgcaag
     3241 aagattatat aaatttggct tagaatctgg gaaggtaata gcagtagtat cacctcttat
     3301 tacaacaacg ctccttattg tattagttgt catatttggt tgtggaggct accaagttgc
     3361 aacaggctct ttgtcagcag gagctttagt agctatagta tattatatgt tccaaattat
     3421 gactcctgta acattaatgg ctcaattttt cactcaagcc caaaaagcaa tgggagcaac
     3481 agaacgtgtc aattcattat tagttgaaga gcttgaagaa gttgttatac ccaataaaga
     3541 aaatgtcaaa gaagacattg aagatggaat taccttctca aacgttgtct tttcttatag
     3601 tgaagaggga ggagtattaa ataatattag ctttacagct aaggaaggta aaaagacggc
     3661 aattgtaggt gaaagtggag tcggtaaaac aactttattt tcattacttg aacgattcta
     3721 tattgttgac agtggggata ttttttataa cggtagatcg atatattctc atgaattaag
     3781 taaatggaga gagaaaattg catacgttag ccaggatacc cctattatgg aagggagtat
     3841 taaggacaat ttagtgtatg gcataaagaa agatataagt gattccatta tttttgatgc
     3901 actaaagagt gcaaacttag actcttttgt gtcatcacta cctcaaggac tagatacgga
     3961 ggttggtgaa aaaggtatcc gcttatcagg tggacaaaaa caaagaatag caattgctag
     4021 agccatcatt agagatccaa aaatactgct attagatgaa gctacagctc atttagatag
     4081 tcaatctgag gcactcgttc aagaagcttt caataattta atgagagata gaacaacgat
     4141 aattattgca caccgtctat caactattaa ggatgcagac tgtattgtag ttatacagga
     4201 aggtaaagta tcagggtgtg gttcgcatta cgaattatat gaaacaaatc agttatataa
     4261 gactttattt aatcagcaaa cattttctaa agaattggtt cttagtggga atgtctgaaa
     4321 aaatcaaaca aaataacacg atttatctgt gccgctaaat gaaagccgaa ttatttaaag
     4381 gaggtgaaaa aatgaatacc gtattggaat tacaagaatt agcgcatgac acagatggta
     4441 aaggtcaagc agcggaagca acagtcatat ccaccatagc agcaacaact tgtgtaacaa
     4501 caactgtaat aactgccggg aaatgaatct tcaaaaatta aatagaccta actgccgtgc
     4561 aaaagttaaa aagccgaatt tatacttgat gaaacctagt aacagttatt aaataattct
     4621 ggggtgctta gttgagcgga gttcagcaaa gcacccagaa ttaattcgct tcttcaccgt
     4681 taaaaatgaa aaatctactg gaaatcaaga gaccaccttc atgccgaact tccccgaacc
     4741 aactgcggaa agtgcacttc catcacccga gtcaatgttc cgtgggccct ggataaaccg
     4801 aagcattact ttaccctgca cttcgatgcg ctcataatca atctggccaa ggatgatacc
     4861 aatgtacaac tacataacta gatcctgaga aaaaaacgtt atttacgtaa ccaaaggccg
     4921 ggattccggt atatggcgga atgcaaggag cagttagagg cccgtggcgg attcgaatgt
     4981 attctaaaaa tagctctaag ttgtgaagag aggagtggaa taatgtcata tcttctagaa
     5041 atcaagaata ttagcaaatc atttggcgat aaaattgttt taaaagatgt aacatttaac
     5101 gtaccatctg gatcaattgt tgggttcatt ggtgataatg gggcaggtaa atcaacaaca
     5161 tttaaaacag tactaggatt aatctcaaaa gatagcggta cagttaaagt actcggtgaa
     5221 gaaaatatac ataaaaatgc aaagattaag gaaaagatag gggtagtatt cgatgctatg
     5281 aatctaccgg ctcatcttac aataaaacag cttaataaag ttttcaaaag actgtttgac
     5341 ttatgggatc aagagaattt ttatagatta gtccattctt tctctttacc cctagataaa
     5401 aaagttcata cattctctcg cgggatgtca atgaagctgt ctgttgctgt tgcgttgtcg
     5461 cataatgcaa aattattact cctggatgaa gcgacgggag ggcttgatcc ctcatcgagg
     5521 gaagaactgt tagaggaatt ggaaaaattt gttaggaaaa gtaacggtgg tatattgctt
     5581 tcctcccata ttatgagtga cgttgagaaa atagctagcc atattgtcat tataaaagat
     5641 ggtgaaatct tactaaatga agagaaagat aaggtttttg aaagttatgc tatcgtagat
     5701 attgatgatg aacaactaaa attactcaac aaagatattg tagtggcgaa aaggaaccat
     5761 gggtcttatt tcagtgtact tgtatcggat agacaaggac taccaaatgg gattgtgtct
     5821 aaaaccattt caatggaaga aatgagtgtc ttattaacaa ggagcgaaaa ataatgagag
     5881 gcctattatt gactaactat tacctggtat atcgaagtat atttgcgtac acaggacttg
     5941 caatcttggt atccggaata atcttatatt ttggaggtgc ttcaatgcgc ggtatagccg
     6001 ctttgttaat tatcttgtta atggctgtac cttcacttga agttataaaa tccgagagta
     6061 agtcgggtta tgacaagtac gtacttactt taccggttag aagaagtaat attgtacaaa
     6121 gtcactactt tttttatttt tcagtcgcgt ttatcggatc tttactatcg tatgtcatct
     6181 tgtatgtatc taatctaatg tcggatacac caagcactgg gatatttaat actgtttcta
     6241 ttgggacttt catagttctc tttgtcggtg cgttagttta tccattcctc tatatttttg
     6301 ggccagaaaa atctgacggt attataattg gaagtgggtt tgttgctgtt tttgctactt
     6361 ttggattacg aaacttagta gaccaaatac caaatataaa tccatcttta tatgttccgg
     6421 ttatatatat aatatttggt gttatcatat atgttctttc ttatttcatt tctgtattta
     6481 tatatcataa gaaagaattt tagaaataca gcggacgcag ggaataacgt cttctaccac
     6541 acggtaactg agacggtaga atgtctattc tttcataaat ggagagtgac tatatatagt
     6601 aattaactca actttcgcag atcgaaaatc agcatgaacg tttgccattg tagggttcca
     6661 gatggatcag atcccacgat tgcaaaatag aaaaacaccg cttcgtttgg taaagtgaga
     6721 gtgacaagct tccactacca gacagaagag gtgtcttcca ttatgataga ccatcagacc
     6781 gatctgaagc aactaccaaa cgaaataaaa cctgcctttc aagaactgaa cgtgctcaaa
     6841 catttacagc aagctggctt tcgtaagcga tttggtttta gctgtgccct gctgtttcaa
     6901 ctcgttttcg tccttttgtt ccatcagaga aactggtttc gcctactcga gagcagcaaa
     6961 ggtgactcga tgcccggcaa ggatgccgtt taccgctttc tcaattatgc cggctgctgt
     7021 gcctggcgtc gatttctgac gtcgcttagc gtcgccacgg tgcaaaaggt caacgctcta
     7081 acgtctgcgg accgggacac cgtctttatc atcgacgatt ccatgttcga acgtaatcga
     7141 agcaaagcct tcgagttgct tgccagattc aaggaacacg ctaccggtgc ttattacaaa
     7201 ggattccgca tgctcacgat gggatggtcg gatggccaca ccttcttgcc gatcgacttt
     7261 cccctactca gttccagcaa gtcatcgatc aatggcatga gtgaaagcat cgacaaacga
     7321 acacacggct ataagcgtcg tcaggaatcg cttctgtcgg ctccggcagt gagcgctctc
     7381 atgctggatc gtgccctcac tgccggagcc accgcatcct acgtcttgat gtacagctgg
     7441 tctacccatg caccgctcat cggcgaagtt gttgcgcgcg gcctggatgt gattggcatg
     7501 gtcgacaaca agcgtttctt gattcaaggc cagaagctat cgatccagga attgtacgcg
     7561 gtggcgcctc ctgtcgtgag caagaagcgc agcaatcttc gttctatcca aaccgagctt
     7621 ccttcgggta ttccggttcg attcgtcttt gttcgccatc gctccaggaa aaacgagtgg
     7681 ctggcgattt tagccaccga tcttacgctt accgtagaag acttcatccg gatttacgcg
     7741 atccgctggg acatcgaggt cttcttcaag tgcaccaaat cgctgcttcg cctgcgatgg
     7801 aatttcaagg ccgttcctac gagttgctaa tcagccacac gacgattgtg ttttcgcgct
     7861 atatcgtact ggcttggcag catcggcaaa gcacggactc acgatctttt ggcggtctgt
     7921 tttatttgtt gtgcgacgag gtcggaacac tcgactgggc tgtcgctctg cagcaactgt
     7981 aagatctcaa cgaagtatcc aaaaaagcag ggaagaagct ttccgctctg attcaccgtt
     8041 aactccagca atggattgcc gctttgccta gttatatcaa ggcttgtttg ctaatttcat
     8101 gctgcgaaag tttgagtaat taattataca tatataagaa aaggggagtg actatgaaaa
     8161 caaacgtgtt cgatctggat gaggtagcta ttcgatcgag tgaacaaaac gggttgcacc
     8221 ttcatctttg cagcacagat aaatttaaaa caatgaatat aatgttgacg atgaagtcac
     8281 ctcttcaaaa agatttaatt actgcaagag cattaattcc ccatattctg aatggaggtt
     8341 caaaaaatta tccaaaccat aagcgaataa aacaaaaact tgatgagatg tacggtgcaa
     8401 cccttttccc aaatgtacaa aaagagggag acaatcatac aatatctttt cgaatggaga
     8461 tccctgcagt tcaatatctt aatgtaacga atactttcat gaaatcagct ttcgatttat
     8521 tacacgacat tgtttacagt cccgttcttg aaaatggtgt attcaattct acgattgtcg
     8581 aacaagaaaa acgctcctta aagcaacgtt ttgcatcaat gtatagtgag aaaatgttat
     8641 atgctagtgt tcgtttaata gaagagatgt ttgaaggtga accgtatcag ctttctgcat
     8701 atggtatcga ggaagatatc gattctctta atgatgcatc tatttatcaa atctataaag
     8761 atctgcttca aaatgatcgg tttgatttat acatcgttgg cgcttttaat gaggatgagg
     8821 ttacattaat ggtccatgat gttttttctg aagagcataa ggacaaacct gtaaatacca
     8881 tttctccagc tagaaaagat agaaatggta ttaagattat tcaagataaa caggacgtaa
     8941 atcaaggaaa gcttctcttg ggttatagaa cttattcgac aatacaagat gaggattttg
     9001 aagctacaag gttggccaac gcgatttttg gtaggtttcc atcttccaaa ctatttatga
     9061 atgtgcgtga aaaaaaaagc cttgcttatt ttgcccaatc ccaactggag agcaataaag
     9121 ggttgttagt aacgatggcc ggaattgatt ttgataatta tgaacgtgca gttgaaatta
     9181 taagagaaca agagtacgca atgaaagaag gtaactttac tgaggatgaa gttgaacaag
     9241 gtaaagcaat gttaattaac ctattacttg aagcatatga tgttcctctg ggaattatgg
     9301 aaatagccat cgaagcggtt gatagaggat tttcaagtaa cttagttgat cagataaaca
     9361 gaataaatag ggtaaccaaa agcgaactta ttcgagctgc caataaatgg gaacttgata
     9421 caatctattt tttaaatagg aaggattaaa taatatggag tcaatgggac tattaaagag
     9481 tcccccatca acactttaac aacattaatt gtaaaaaagg gttgaattaa aattattcca
     9541 aatgatccct tgtaatacaa taatgaagat atatatcttc tattactaaa aaataaaaat
     9601 ataatattaa ataaataaaa aataagtaga aagcgttgac agagtcacta ccaaacgtta
     9661 ctataaaggc tatattatat tgtaagaggt tattattacc gtattccttg aaccatactt
     9721 ctagctccga cagattactg cattcgtaca gaaaaggcaa cggaatgtag cttttacccc
     9781 cttttatatc acaattataa gcttaaatct gatcagcaag cttttttgtg aaaactccaa
     9841 tagtcaatca taataattca ctcctgtctc aactagattt tcttccgtag gtagtattac
     9901 atcataaaag tgagtaccaa cagcaagagg taattagaaa taggcaagct ttccctagat
     9961 atgtggaata cacaaataat gaaatatggg cgggatatgt atggaaggaa atatgcttta
    10021 ccatcagtac ttgaaaccaa attcagaata ttacgaaaaa atgagcgcga cagtaaaggc
    10081 atatgaagtg aatgagattc ctgatacata tgctgttatt tcagacaatg actccgtttg
    10141 gaagcactat catgttaagg gattaacact accagagcaa ggatggaaaa ttcatgtaac
    10201 tgcgacatta gaagattcac agggtgtgct agaaaaggtt tctcggttat gtatagatag
    10261 aaaaattgac ttcaagcacc ttaaggatag aaacagtttt cttgagatga attcgaaaaa
    10321 tgctaatcgt gcttcttctg ggaaatttat aacaatatac cctcttaata atgaaagctt
    10381 tgttgacttg ttagaattga tttcttcaac agtccgggat tttcaaaaag gaccttatat
    10441 tcttaatgat aagagatgga aaaatagcaa tgtcttttat agatatggag gatttaaaag
    10501 tataattaat gaacatggtg aacattgtat tagagataat caaggaaatt taattaagga
    10561 tcaaagaact cctttttacc aagttcctga ctttgtaaag gatttcgatg attatctgaa
    10621 taccattaat aatgacttgg aaacgaaagc ggatggcaat ttagagaaat atgagattga
    10681 aacggcactg acctatagta atgctggtgg ggtatacctt gcgactcgaa agaaagataa
    10741 tatgaaagtg attatcaagg aagccagacc aaaggcaggt ttagatgggg taggtcaaga
    10801 tgccttatct aggcaaaaaa tcgagtatga tgctttgaaa aaacttaaag atgtacccgg
    10861 tgttgtgaat ttgatagagt atttccaaga atgggaacat tgttttttag tagaggaatt
    10921 catagagggg caagacttaa ggcaatggat ggcccgagat tttccattca ttaaagacag
    10981 tgatcgtttg cgtgatcacg ctgaaaaagt taaaaagata ctgttacaac ttttctcact
    11041 aatacataat atacataaaa atggagtggc gatgggtgat ttgcaaccat caaatgtaat
    11101 ggtaaccgag gacttaaccg ttaggataat agattttgaa actgcgatgc ccgtaagctc
    11161 tgaagacaac cctagtatgg ctacgactgg atttgtttcg cgggaaatga aagtcagtgg
    11221 tgcgagagat tggttcggat taaagaaaat tatactcttt ttggcacttc cagtcctttc
    11281 ctcagaagat ttagaggggt atctacaatc taaccatttt aattggataa aagaaaacta
    11341 tggagattca ttttatcgtt tcattgtaga tttacaagaa aaatgcaata agagaataaa
    11401 tgactaccaa aagtataccc cgaaagaaat taacctctgt gatcagccaa gtgactttaa
    11461 catctcttct attattgata agttaataaa aggaattgaa aataatttaa ctaatgatga
    11521 aaggttcatt aacggtgaca ttcgtcagtt catgatgagc ggggcgaagt tcaacttttt
    11581 aactggcgga agtggcgcag cttttacact tactaaaaaa caatctaaaa ctgtagaagt
    11641 agatcaatgg attcaaagtt ttttattaga caatttagat cgaattgaag acaatggatt
    11701 gctgactgga aagacaggga tattggcttt gctttatgaa aaaggttata aagaagttgt
    11761 cttcaatgaa atgaaggttt taaaagataa cattaatgaa actaatattt ctttacgctc
    11821 aggtctttca ggaataggtt tattcgtaat tagtttatac ctggaaacag agaacaaaga
    11881 atatttacaa tttgcaaaag aaatagaaga attaattgaa tgtaacagag ttaaaggtga
    11941 accgttaaga gttagtgact ggatggcggt taatataggt gcgattgatg gtttatccgg
    12001 ggtagcgctg ttttattcag cactttattc agctaccaat aataaaaaat atctaaaaaa
    12061 ggctgagtta ttactaaagg aagatttaga atcaacaaaa aaagatgatg cgagtggtgt
    12121 gttacaaaca ttagataaga gaaatcgcct tttgccgtat ctttccggag gatctattgg
    12181 aattgctatt tcaatttggt ttttaaatca tgtgagtgga caagaccttt ataaagaaga
    12241 gatggatgcg attttaaaat tatcaaagat ttgttgtaca attagtggaa gtttatttga
    12301 tggcgcaggt agtttccttt taatcccttc catggtggaa cgtagtaaaa aacgcgagaa
    12361 aatggttagt gaggtcttgg agttacttaa tattttttta attgagaaga atggttatta
    12421 tgtatatcca ggacaatttt cttttagatt agccgatgat gtttatacag ggagttcagg
    12481 aataatttta gcattaatgg gggtagtcaa agataatcca ctctattggt taccattgat
    12541 caattcggat caatttctag aaagaacaaa ggccaaggtt ctagcagtaa gtggtgaaca
    12601 agtgtaatgt ttagcttgca aaatgagcgt gtgacactga tggtaacagg ccagagggag
    12661 gctgtaacag taacaacgac tctagcaatg atgtggtcga cagcaagtat tcggtgccac
    12721 taaatgaaag ccaaattata aactatgtaa aggaggtgag aaaaatgaac acagtattgg
    12781 aattgcaaaa attagcgcat gacacagatg gtaaagggca agcagtggat gcaacaccaa
    12841 caacagttac agtgacaaca gtaacaacaa ctgttgctgg ttggtcgaca caaagtcagc
    12901 atcactgcta aaaagaatct caaaattaaa taactgccgt acaatagttt ggaggtgaaa
    12961 aaaatgaatg cggtattgga attgcaaaaa ttagcgcatg acacagatgg taaaggccaa
    13021 gcagcggatg caacaccaat attaactaca ccaactcgtt ggtcgacaca aagtcagcat
    13081 cactgctaaa tgaatcttaa aaaaataaat aactaccgta caaaagttgg aggtgaaaaa
    13141 aatgaacaca gtattggaat tgcaaaaatt agcgcatgac acagatggta aagggcaagc
    13201 agtggatgca acaccaacaa cagttacagt gacaacagta acaacaactg ttgctggttg
    13261 gtcgacacaa agtcagcatc actgctaaat gaatctaaaa aaattaaata agaataactg
    13321 attgcaaaag ttaaatgcca aatttattct tgattaaacc tagtaacaat tattaaataa
    13381 ttctggggtg cttagttgag tggagttcag caaagcgccc agaataccta tcatactcat
    13441 aaatcataag aaaatcaaga gagggcgata aattcacttt aacgaggata taactggtgg
    13501 tagtagggag agcagtttta ttgatgaaac tattgatttt attaatagcc ttgcgccagt
    13561 agagaaatat aaaaagatta ttgacgttgc ttgatccatc gaaaaaaaac ctctatgctc
    13621 catcgtgctt tatagatcgt ggcgatttgc tcagccgata catgcagcaa gctcgttgcg
    13681 acacgaatct ctgatcctga aaaagtgcgc cgtttctcgg accggccttg ttcgataccc
    13741 cattggcagg tgatgtctcg cgtgacattg gttccttcca cggcttgtcg ttgtaatgat
    13801 tgcggcgtga ccaaggtttc tttaatccgt actacgaaat attggtgtta cttctcgtgc
    13861 gtatcgaaac gttcaatctt cccgtaagcg cgatcctcga ccatgatata gtcgggattg
    13921 gccagctttt caccgatcgg cccatcatgc ttgatcgtca ccgttttggt aactttcacc
    13981 ggttgcttgg ccgccacatc gtaagctaca tttacgctcg gcaatccaca gtccgcagcg
    14041 cggtctgcac cagaccgata actttcccac taactttccc aattgcctaa tcagcttcat
    14101 ataacatctc atttaacgca gcgggccgag acaagctcga cctcttccag aagaagcatt
    14161 tcgaggtgaa aaaatcgctt aagcaagcaa aaaccagatc tgctgactga ccacagcagt
    14221 tttgtttttt atctaacatt cgacatatgt atcactattt ttggagccta ctgtaactgc
    14281 taaactagaa ttaacggatt ccgctaaagg tcaagtccaa atttatgtgt aaaatcctcg
    14341 atgagattgc cagagtaaaa agatgcctaa gctgcagtcc tgtcgagctt cttccgccac
    14401 tcatggtact ctttcatctc aatatacttt tttccggcag accacttttc gtcctgctca
    14461 atcaacaagg ctccaaaaag gcgaaggaca gaggctcggt tgggaaaaat gcgaatgacg
    14521 cgttctcgac gccgcaactc gccgtttaga cgctctacag catttgtggt gcgcgtacgt
    14581 atccgacagg cagccggaag ggccaagatc gctgtcgcat cgtcaaagcc ttcttccaag
    14641 accctcatgg cctttggagc tttatcgtca aatgcttctt gtgtccgctt cagcagtgta
    14701 cgggcactgg tctcgtccgc agcttcgtag atggccctta catgggcctt ctattcatcc
    14761 cgcgcactga ccaaaccacc gtgatggtcg cttgtaatga catccacacc gtgcaacccg
    14821 cgacttttga ggtgcgtaaa gaaagctccc cacgttgcgg ctgactcggt atcatcgacg
    14881 gtaagtcaaa gcagttcccg gtagccctcc gcattaatcc ctgttgcaat catcacgcca
    14941 cgtgagcgaa cacgaccgtc ttcccggact ttgacgtaca gggcatcgac aataagaaag
    15001 gggtagggct tgtccagttt tcggttattc cactcctcaa cgaggggatc cagttgtttg
    15061 cagagttcac taacggtcga tttggagaac tccgttccac acagttcttc ggtgatattg
    15121 ctgatttttc gcgttgacac accattgagc accatctcca tcatggctaa gacaagggct
    15181 tgctcactgc gttggtatcg agaaaaaagt tctgtagaga accgaccgtt acgaaaacgc
    15241 ggcactgctt gcagggttaa ttgccccacc cgtgttgtca gccgatgagg ataggatcca
    15301 ttacggtaag ccgcacgttc ttctgagcgc tcatagtgcc ccgccttcag ctgttccgtt
    15361 gcttacgcct gcaatacttg attcaagatg gactctaata ggccgctatc cccgcatctc
    15421 ttgattcgga taaaaacagt tgatgcaaaa gttgtgaatc tagggtaatc tggtattgag
    15481 tcatagctag atcctccttt ggaatgttgt ctcggcaact tcattctata cgaggatcct
    15541 tgctatggct cttctttttt ttcatttgct ttttacacaa ttatatggac ttagcttagc
    15601 gaaattagga atgctgcaaa aatacatcac ttaccctacg gctaggcata aatggcattc
    15661 agcatggcga aataatgtaa tttctcctag gccccctaat taaactggag cttccggctc
    15721 caatattata agctgttatc agagggggac aactagtatg ggaaagcact ttagcaggga
    15781 aaaacgccgg caaatcgtaa aggaagcaat ggccggcatt aaggtgggaa cacttgcccg
    15841 aatgtacggt gtccatccgg atttagaaaa agctgcatgg aaagggtgtt ccttattttg
    15901 agatcaacca aaactatgag gaagaaatga ccgaggtcta tgattatatc gagacgcaaa
    15961 aacgcaaaat cgtcgactgc aggatgcagc ccccgcactg aggcgtgtcg gcaaggtcga
    16021 ttgatatcac ttacttggaa aggaagagac gatgaagaag ttcatatttc gcagcagttt
    16081 tattattgat tgcgggatgc gccagtggca ggggagattt gcaccgactg cgtacccttc
    16141 taaatatgcg gaaaagaacg gtcatattgt ggtagcgccc tccggactca aaaatgcgga
    16201 gaaaatggaa gaattcctgg ccaaacacaa cgacagggag aaggcagcgt tgcggatgcg
    16261 atgtattcgg ttgaagggga tgccattctt tatgatgtgc atacagacgg agagacgatt
    16321 caatatacaa tagacaatac cagagattca tttgcccaag atgccggtat tcaagagacc
    16381 acctgcaaga acatcataaa agaagaggac gcgaaacaag ttacctatat gatcgagggg
    16441 gcaaggaatg gataggagga tcatatattc caactaaaaa tatcggaata ttattattga
    16501 cgaagcagga ataaccgctg cctggattaa ggaaaaagcg gcggagcgca tgctggaggc
    16561 ccggaaaggt tcagctaaag aagccccact acccccacaa acaatacgtt tcggataact
    16621 acaagaaaaa gtaagaaccc gccttaggtt agctcctagg cgggttctta tgctttggta
    16681 cccatccaca ggaattccaa gcattgctgt agtccccttc attgtcctgg acttggaaca
    16741 cgatgcagtc ctgtccccgt tctgcagctt taaatcaatt ccggcatatg gccgaaccct
    16801 ctgattaagt ctccgattca actttcgcat cgctaatgat cgtaacacaa gtggtttgcg
    16861 ttcctttctt ctttttttct cttcatttgc atatcagtag aggtaaggcg tttgccaatg
    16921 cgcttgtcgg cgataaggaa ggctgaaggc gtataatgct ccatcttcat tttaccgctg
    16981 caagggcagt ccatgcttcc ttgaaagagg aaagaagata gaaaaggaag gggaggtggc
    17041 aagtatgacc cgcttagatt ctccaggctt acgcttgcgc caagctgttg aggaagagcg
    17101 gccgctgcag gtggctggca cgattaacgc ctatgccgct atgctggcca agtccgcagg
    17161 cttccgcgcg atttatttgt cgggggccgg tgtggccaac gcttcattcg gcttgccgga
    17221 tctgggcatt acgacactga acgatgtgac ggaggatgtc cgccgcatca cttcggcggt
    17281 cgacctgccg cttctggttg atgccgacac gggattcgga agcgccttta atattgccag
    17341 aaccatccgg gagatgacca gagccggggc ggcgggcgtg catatcgagg atcaagcgat
    17401 ggccaaacga tgcgggcacc ggccgaacaa agcgattgtg agcaaggacg aaatggccga
    17461 tcggattaag acggctgtcg atgccaggac ggatggctcc ttcgtcgtta tggcgcgcac
    17521 ggacgctctg gcatccgaag gactcgatgc tgcgatcgaa cgggcagctg cctatgtgga
    17581 agccggggcg gacatgattt ttgccgaggc ggttactgaa gtgtggcagt accggaaatt
    17641 cgccgaagcc gtgaacgtgc cgattcttgc gaatattacg gaattcggcc agacgccgat
    17701 gctgtccgtg gaggagcttg gagccgccgg cgtcagcctc gtgctctatc ctctgtccgc
    17761 tttccgcgct atgaatgccg cggctttaca ggtgtatcag acgatccgcc gcgaaggaac
    17821 gcagaaaagc gtcatcgata tgatgcaaac acgcaacgac ttgtatgaat atttgaagta
    17881 tcacgaatac gaaaaaaagc tggatgaatt gttcgctgcc ggcaaggagg gacaataaat
    17941 gacaacggcg aaaaaacaag gcggattagc cggaatcatc gccggccaga cggcgattgc
    18001 caccgtgggg aaagagggga agggcctgaa ttaccggggg tattccatct acgatctggc
    18061 cgagcatgcg accttcgagg aaacggccta tctgctcgtt tacggaacat tgccttcttt
    18121 cagtgaattg tccgcttatc gctcgaagct gcagcgcctg cgcggacttc cggctggtct
    18181 gaaaagggtg ctcgaacaac tgccggccgg atcgcacccg atggacgtcc tgcgcacagg
    18241 gtgctcggtt ctcggcacca tggaacctga gggtcctgga cgcagccaca gcgatattgc
    18301 cgaccgcttg atggccagct tcggctcgat gctgctgtat tggcatcatt atgcccagac
    18361 cggcgcccga atcgagacgg aaacggacga cagcagtatc gccggacatt ttctgcattt
    18421 gctgcacggc aagaagccgg aaccgctgca tgagcgggcg atggacgttt ctttgattct
    18481 gtatgcggag catgagtaca acgcttcgac ctttgcctcc cgcaccgccg cttctactct
    18541 gtcggacatg tattcggcga ttacttcagg catcggcacg ctgcgcggtc cgctgcacgg
    18601 cggcgcgaac gaggcggcga tggaactgat ccaacagttc cgcacgccgg acgaggcgga
    18661 ggcgggcctg cgccggatgc tgcaggagaa aaaacggatc atgggcttcg ggcaccgggt
    18721 ctattccgtc tccgatccgc gctccgatgt cattaaggtc tggtctcgca ggctgtcgga
    18781 gcatgcaggg aatatgaagc tttatcgcat ctccgaacgc attgaatcgg tgatgcggga
    18841 agagaagaag ctgttcccga acctggactt ctacagcgct tcggcttacc atctgatggg
    18901 catcccgacg gcgatgttca cgcccgtgtt cgtgatatca cgcacgagcg ggtggtccgc
    18961 tcacatcatc gagcaaagag cgaacaacaa gttgattcgc cccaacgcgg aatatatcgg
    19021 tccagaaccg cagccgtggc tgccgatgga atcgagaaca taagtactcg taagggggaa
    19081 tgcactatgt cgtcacatct cagcaatgca agacctgatc atgatcaagc gattaaggat
    19141 atcgctgctt atgtaggccg ggcgattgat agcggggaag cgtaccggac ggcccgatac
    19201 tgcttaatcg attcgctcgg ctgcggcatg ctggcgcttc ggtacccgga gtgcacgaag
    19261 ctgctaggac cgattgtgcc gggaacggtc gtgccgaacg gtgccaaggt gccgggtact
    19321 tcctaccagt tggatcccgt tacagccgca tttaacatcg gcgccatgat tcgctggctg
    19381 gattacaacg atacgtggct ggctgcggaa tggggccacc cttcggacaa tctgggcggc
    19441 attctggccg tggccgatta tgtaagccgg aagaacgctg cggaaggaaa agccccgctg
    19501 ttgatgcggg acgtcttgac agggatgatt caagcgcatg agattcaagg cgtgatcgca
    19561 ctggaaaaca gcttcaaccg cgtaggactg gaccatgtcc tgctcgtcaa agtggcttcg
    19621 gccgccgttg ttacgaagct gctcggcgga accgaggagc agatcatgaa tgcggtgtcc
    19681 aacgcatgga tcgacgggca atcccttcgc acgtaccgtc atgcgcctaa tacgggctct
    19741 cgcaaatcgt gggccgcagg cgatgcgaca agtcgcgcgg tgcgtcttgc catgatgtcg
    19801 ctgaagggcg aaatgggctg tccctccgca ttgacggcga aaacctgggg cttctacgat
    19861 gttctcttta aaggcagcga gttcaagttc ccgcgtcctt acagatcgta tgtcatggaa
    19921 aacgtgctgt tcaagatttc gttccccgcg gaatttcatg cgcagacggc cgtggaatgc
    19981 gcgattcagc tccatccgga cgtcaaggac cggctggacg acatcgacca tattgcgatt
    20041 gccacacacg agtcggcgat ccgcatcatc gataaaaaag gaccgctgca caacccggcg
    20101 gaccgcgatc attgcctgca gtatataacg gcaatcggac ttattttcgg tgagctgacg
    20161 gcggatcatt atgaagattc cacggcaaaa gatccgcgta tcgatgccct gcgggagaag
    20221 atgatagtag tggaaaatcc gcaatattcc aaggattatc tcgatccgga gaagcgctcc
    20281 attgccaatg ccgttcaagt gatgttcaag gacggctcca ggacggacaa cgtggccgtt
    20341 gaatatccga ttggccaccg ccgcagaaga gcggaaggca ttccgttgct ggtaaagaaa
    20401 tttaaaaaca atttggagac gcgtttcccc gcaaagcaag tggcggacat tttggagctt
    20461 tgcgaaaatc aagagcgctt ggaagcgaca cccgtacacg tcttcgtgga caagtttttg
    20521 atctgaaaag caagctggcg ccggtactcc accggtgtca gcttgttccg cttttgctgt
    20581 cttctcgcca ttgtgtacaa acgccgtaca ttttgtccgc ttgaagttcc actcttgctg
    20641 aagcgagtcc gtccttactc cggcgcctcg ttttgaaaaa attcctcaac ctttttcatg
    20701 aacaccttgg cagccatgct gctgtacttg tcgctgcgat aataaatcta caatcccgaa
    20761 ccggcgatcc cttaatggga atggagtgtt ttctttcttt attcatttcc aatattatga
    20821 attgaagtta tactaagggg aagagatggc ggacgaatga aaaaggacca tcaagaagta
    20881 cctatcaaat gtactggtat tgcggcggtc ttactgaaaa aatgcaatga tgaatgcaaa
    20941 gtgcttttat tgaagcgtgc cgctccgccc ttgaaggatg cctggtatta taaattttat
    21001 ttacattgcc ccggtttttg ttgggtttgt tgaaggagaa caagatgtag tattgaatca
    21061 ggaacataca gcatatcaat ggctgtcatt tcaggaagca aaagaaatcg ctttacccgg
    21121 aaatgatgaa gttctggagt ttattgaaaa gcattttata aaaaagaagc cttctatttg
    21181 gttatatgta gggggaggca cgaatgatgt ataacagagt tgatgttgcg tgcgcattaa
    21241 tatttgatca agccagcgag aatgtggtga tggtaaaaaa taaaaaaggc gactcctgct
    21301 attggagcct tccaggcgga gcagttgaag caggggaaac gctagaagcg gccgtaatac
    21361 gtgagacaaa agaggaagcc ggatttgaag ttgaggcagg cgggctttat tcggtgagtg
    21421 aagctctctt ttcgaattgt cagtgcctgc actaaattgg aaatggagat tctgtgtaat
    21481 gataatatta ataagcggca acagttgcac agggaaaacc ttaatgtcgc aaagattgct
    21541 tgaaaaatat ttgattcctt atttttcggt cgatcacctc aaaatggggt tatacagatc
    21601 ggatagcaac tgcggcttta caccacagga tagtgatgaa gcaattggcg agaagttatg
    21661 gccgatcatt aaagggatga ttatgacgag tattgaaaat aatcaaaaca tgattattga
    21721 aggttgttat atcctggctc gctttatcaa ggattttgaa aaaccatatt ccgaaaacat
    21781 catatccgtg tttctcggtt tttcaacgaa ttatattaaa caaaactttg actccaacat
    21841 agtaaagcat agaagcgcga ttgaaacccg cctctatccg gaagagcgca cgatcagtcg
    21901 attcatcgat gagcatgatc attttagacg aagctgcaag gaatatggtg ttccttattt
    21961 tgaaatagat caaaattata aggaagaaat tatgaaggtt tatgatttta ttgaggttca
    22021 aaaacgtaag atggaagcaa attaaatgcg ggggaagctt catccgatag taagataaaa
    22081 taaattacct aaaagacaat attaattaag ggatgagaac tggcatgtca agaggtacaa
    22141 caatttcatt atttttagtc gatggaaatc catcgggaat catatgtgct tatctttcta
    22201 actggacagg gcaagctgtg agaaggctaa aactagatca gaggtaaata gaataggagt
    22261 atattttctt tttggattta gtgaacaagc acccgatgaa agaattgttt acataggtca
    22321 atcagataat atttatgaat gattggtcca acatactaag gaacgcaaaa aatcttcatt
    22381 atcagagatg gcaatcgctg atatggacac ttttatagat aatattaaaa ctgttttacc
    22441 aacattagga tacgatctgt taatagaacc tgcgacgaat agagaaaaga agaacacaac
    22501 attttatttg gatattggag gattaaaagc aacaggatat ctttctaata atggatttgt
    22561 tgtaatcaag ggaagtgacc tgtctctgga attaaaagag tccttat
//
