LOCUS       NZ_CP089312            22089 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. GQFP chromosome.
ACCESSION   NZ_CP089312
VERSION     NZ_CP089312.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GQFP
  ORGANISM  Streptomyces sp. GQFP
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8306813)
  AUTHORS   Zhu,J.
  TITLE     Complete Genome Sequence of Streptomyces lacrimifluminis strain
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8306813)
  AUTHORS   Zhu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-DEC-2021) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Dongchuan Road No.800, Shanghai
            200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4; canu v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 109.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:27:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,499
            CDSs (total)                      :: 7,422
            Genes (coding)                    :: 7,228
            CDSs (with protein)               :: 7,228
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 156 of 194
            Pseudo Genes (internal stop)      :: 7 of 194
            Pseudo Genes (multiple problems)  :: 35 of 194
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:04:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6581931
            Orig. end                         :: 6604020
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089312.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22089
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="18"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22089
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22089
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12089](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12089)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            <782..>924
                     /locus_tag="LUX31_RS29625"
                     /old_locus_tag="LUX31_29625"
                     /pseudo=""
     CDS             782..>924
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014043973.1"
                     /locus_tag="LUX31_RS29625"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="LUX31_29625"
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLLWVSPALPGRAHDLSAARIHRIIRVIRICECQGVPSSPTVPVR
                     EP"
     gene            1370..2017
                     /locus_tag="LUX31_RS29630"
                     /old_locus_tag="LUX31_29630"
     CDS             1370..2017
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LUX31_RS29630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LUX31_29630"
                     /product="hypothetical protein"
                     /protein_id="WP_235478361.1"
                     /transl_table=11
                     /translation="MAAQAAPADELGVALAAPFNPSCKLVKAPDAPGEFDLVLAGFKPR
                     QEVRISGPEKFTRQVNKQGSFTEQDVKKGTYTATVQVKKKKVSVPCTKPPRSPAVDITE
                     ASANLVSPGRSQSVDCRRRQRATFGGTLTGKGTGSVKYVWTSSDGKRAERTLNFTGPTA
                     TVEQFSVTIPAREKRSDPRPRVTVQLRVPKQQGQEGVSSSNVTLVLKCRFPS"
     gene            complement(2111..4213)
                     /locus_tag="LUX31_RS29635"
                     /old_locus_tag="LUX31_29635"
     CDS             complement(2111..4213)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019607.4"
                     /locus_tag="LUX31_RS29635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29635"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_235478362.1"
                     /transl_table=11
                     /translation="MATSPGTRPGAHAPLILLIALALLLSALVALPGRALAAAATGPLT
                     DPIPERPAASGIGLTVEEYASFPKTDPPPGPVTDPRLMRQARINYLSELPDRSGRKAVP
                     DLNGKLYLVKDGSSPALYLDIAATFSPAFFASRGLGQGFGFVTFDPDFRRNGRFYTVHT
                     ELASATTAVPDYRQQASTVYHGIVTEWTAADPSADTFSGTRREILRIGFAGTIHGIQQI
                     DFNPTALPHDPDRGLLYLAVGDGGQGVRNTEPQTLSLPHGKILRIDPRGTNSANGKYGI
                     LAQNPFTATPGALGEIYAYGLRDPHRFSWDPAGSHRMYVGSIGQHAVESVYEVRAGDNF
                     GWSEREGPFVFDKTATDPCDQILPLPEDDEKYGYVYPVVAYDHDPPADWDCTSDVGRAV
                     VGGFVYRGSDLPALRGKYVFGDIVDGRLLFADTKDMRRGSGQLAQLYDLMLYDASGKRV
                     TMRDLAEDPRVDLHFGRDAEGELYLLSKANGRIWKITGTREFASCDTTGSQLTHVMDGR
                     NWAPVTPSKWRFPGREAVLAEAGVQRPGPRRPYEYAVLTAGPAAYGDVRIDAEVRIDTP
                     VDTPNRDVIIVFDYQSDTKFSYAHLSQDNTIYPHNGIFVVDDSDRLRIDDQWNGTTGAP
                     PAITDTAWHKVRVVRCAGTGEIAVYVDGSKRPLMTAVDTTLASGRVGFGSFDNTGRLRG
                     LRVSSP"
     gene            complement(4248..5201)
                     /locus_tag="LUX31_RS29640"
                     /old_locus_tag="LUX31_29640"
     CDS             complement(4248..5201)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009997972.1"
                     /locus_tag="LUX31_RS29640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29640"
                     /product="LamG domain-containing protein"
                     /protein_id="WP_235478363.1"
                     /transl_table=11
                     /translation="MRSRRNTLAAAVAALLTALATTAAAPAGGGRGEGSVLPSLRPHLA
                     AYYDFEHPVRGNPARERDLGFSRTDIDLIGGGARMRTDDGAHRGSRTSLQVRQITPDAK
                     GNDDWKAGVYGPSGVPTLRAFKGVEGMTVMGWFKMSGPNPALNTNTAAPDDRYGAVGLA
                     GVLSGDSDGHAVRGLLEIIEVNGELKLVALGRRVDGAASQTFAASQDWRTLLPIGEWVF
                     LAATFDFDTGAMALYRNGRPLDGSYTVPGDPWDLAAPGPHRTSPTDPRGIKIGGSFPQN
                     TVERNPCDCRMDSLMFLDSAVGGDRIRAQYRLMAAR"
     gene            complement(5219..6004)
                     /locus_tag="LUX31_RS29645"
                     /old_locus_tag="LUX31_29645"
     CDS             complement(5219..6004)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="LUX31_RS29645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29645"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_235478364.1"
                     /transl_table=11
                     /translation="MASDAHTDPGSGASSGTDPAFLLELDDIRAGYGRAALVLRGLTVR
                     VPAGAIVCLVGPNGAGKSTVLKVASGLLTPRSGRILVDGEDVTGRGPQRMLAAGVAHVL
                     QGHSVFREMTVAENVLLGGYTLRDKALVAERADFVRELFPVVAERWTSLAGLLSGGQQK
                     QVEFARSLMVEPRVVLLDEPSMGLDPKATGVVFEQIVRMRDAGTAVLLVEQNARRALEA
                     ADTGCVLDLGRVHIAGPARELLADPQLGELYLGGRPARR"
     gene            complement(5994..6791)
                     /locus_tag="LUX31_RS29650"
                     /old_locus_tag="LUX31_29650"
     CDS             complement(5994..6791)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="LUX31_RS29650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29650"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_235478365.1"
                     /transl_table=11
                     /translation="MNEAAPDRAPEVEPDAESDAEPEPSLATTGLTKAFGGVTALDSAS
                     VTFHHGKVNALIGPNGSGKTTFFNCVTGMIRPDSGRVTYRGRDLTGRPPHRIARAGIGR
                     SFQLCRVFPRMTVLDNLLAAVRPHGLTGQLGRSGTRAETERARYWLTRMGIEHLEQAEA
                     RQLSWGQQKLLELAGVLTSEPELILLDEPAGGVNPALIDRIGDLVRELNAEGRTFLIVE
                     HNMDMVMSLSDHVVVFDRGRPIAQGPPSLIQSDERVLGAYLGV"
     gene            complement(6772..7887)
                     /locus_tag="LUX31_RS29655"
                     /old_locus_tag="LUX31_29655"
     CDS             complement(6772..7887)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014684.4"
                     /locus_tag="LUX31_RS29655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29655"
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="WP_235478366.1"
                     /transl_table=11
                     /translation="MRNGSDSSDFRSRLVHPRYVHLGVLLLAAAVALSFPSMAPSPYEI
                     TVGIAILNYAVLSTSWNFVGGFTGYVSLGHGAFAGLGAYGTGLLVAKGELPPFAALFVA
                     AVLVAALAVPVGYAALRVRGASFVIVSIALVLILLLVFQSWASLTGGSRGLVVPRPFPG
                     MLRAEHHRTFYFLFLSLLALALLVWWVIDRSRFGMGLKAIREDEDKAQSLGIPTFTYKL
                     VVFVVSAAFTSLAGGLYALWFGDLDPVFQFSILSGSYMVLMALLGGVRQLYGPLLGALI
                     VGYALEYSKVEYGDTPLHLVVAGLLLGVVVTFMPDGVIPAAGALLGRFRRTGDASIREV
                     TAAELRERGGEFEETDGRDTTEVRNSERSGT"
     gene            complement(7871..8758)
                     /locus_tag="LUX31_RS29660"
                     /old_locus_tag="LUX31_29660"
     CDS             complement(7871..8758)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014684.4"
                     /locus_tag="LUX31_RS29660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29660"
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="WP_235478367.1"
                     /transl_table=11
                     /translation="MPSASLVFQSLVLGVLLGGLYALLAAGLTLYFGVMRVVMIAHSAF
                     LILAAYLAWFAHRETGVDPLLTLVVTVPLFFAAGVALQRLLLTRLRPATLTMMSVLLTF
                     AVALVIEGLLGYAFSGTQRRVRLGYSSASIEFLGARVAVVKLIAFGMAALALLGLYLLM
                     KHSRFGQALRATIQHPDAARLLGIDTDRIAGYGFGLGLATAAVGGTALALDTTIYPSLH
                     WHWIGPLMAIIVVGGLGSVPGAAIAAMTLGILQSLLQLELSTTWAQTVFYVALFATLAV
                     RPQGFFGGRLAQRF"
     gene            complement(8766..10004)
                     /locus_tag="LUX31_RS29665"
                     /old_locus_tag="LUX31_29665"
     CDS             complement(8766..10004)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024850.4"
                     /locus_tag="LUX31_RS29665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29665"
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_235478368.1"
                     /transl_table=11
                     /translation="MTRTHRKQGRRQAGITAGTLALLLAASACGSGAGSQDSADDPIVI
                     GVSLPLTGDFSEPGKGVERGYKAWATIVNDKGGLLGREVELKILDDQSNADRVVSDYEQ
                     LIGRDEVDLLFGPFSTRLVVPSARLAEEYGMLFVEPAGAAPEVFEQGFKNLFYAAPAVA
                     DDHYNLLADHILAMPASERPKTVAYAAMDDPFAQGTAYGLKEKLEKGGVRTVADEVYPP
                     NTTDFGSIAAQIADSKADMVVGGTQYQDGVNLIVALQQLDYQPKLAAFSTAPTQPEFAK
                     AIGDKTEGILAPTGYTQKADYPSNKEFVEKYTEQFGKAPEEDEANAYTTGQVVAAAVEA
                     AQCASQDPDCQSKLVEWLRGNQVDTVVGPLKWDDKGRPQSAHMIQQWVGGEIQIVLPEA
                     QKETGLVYPKPEW"
     misc_feature    complement(9858..9860)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(9936..9938)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..11140)
                     /gene="pqqE"
                     /locus_tag="LUX31_RS29670"
                     /old_locus_tag="LUX31_29670"
     CDS             complement(10001..11140)
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669244.1"
                     /locus_tag="LUX31_RS29670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29670"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_235478369.1"
                     /sec_met_domain="PF04055 (E-value: 5.5e-21, bitscore: 74.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3e-05, bitscore: 23.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2e-06, bitscore: 26.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.6e-07, bitscore:
                     29.2, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSPPPDTAPPPPWALLAELTHACPLHCPYCSNPLELTRRSHELS
                     AEEWADVFRQAADLGVVTTHLSGGEPLLRRDLTAVVAAAEGAGIYTQLVTSGVGLSAAR
                     MSALVSAGLRSVQLSVQHADPVASDRIGGHRSFGAKERAAGLVRDAGLPLGLNVVLHRD
                     NLDAVDDIVDLGVAWGAERIELANVQFHGWALRNRTALLPTRDQLSRAREAVERRREQL
                     AGTTELVWVIPDHFDGVPKPCMGGWGAVSLTVAPDGAVLPCPASRDLLGPDDVPNVRDR
                     SLEWIWTSSPAFERYRGTEWMVTGPCGGCPRREIDFGGCRCQAHALTGDAARTDPACAL
                     SPDHALVRTLSRASRTDAPHYVYRGLDRHHTEVTRGVKR"
     gene            complement(11137..11400)
                     /gene="pqqD"
                     /locus_tag="LUX31_RS29675"
                     /old_locus_tag="LUX31_29675"
     CDS             complement(11137..11400)
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056909.1"
                     /locus_tag="LUX31_RS29675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29675"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_235478370.1"
                     /sec_met_domain="PqqD_RRE (E-value: 3.4e-19, bitscore:
                     67.2, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 8.4e-11, bitscore: 40.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGTGWRPALARSVVLRHDRVRQAELLVLPERVVVLSGRAADVLR
                     LCDGHRQVGEIVDALAARFPGAPVAEEVPRFLDRVREEGWLR"
     aSDomain        complement(11143..11382)
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LUX31_RS29675_PqqD_RRE.1"
                     /evalue="1.30E-21"
                     /identifier="RREFam006.1"
                     /label="LUX31_RS29675"
                     /locus_tag="LUX31_RS29675"
                     /protein_end="86"
                     /protein_start="6"
                     /score="67.2"
                     /tool="antismash"
                     /translation="RPALARSVVLRHDRVRQAELLVLPERVVVLSGRAADVLRLCDGHR
                     QVGEIVDALAARFPGAPVAEEVPRFLDRVREEGWL"
     gene            complement(11427..12089)
                     /gene="pqqC"
                     /locus_tag="LUX31_RS29680"
                     /old_locus_tag="LUX31_29680"
     CDS             complement(11427..12089)
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962381.1"
                     /locus_tag="LUX31_RS29680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29680"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_235480106.1"
                     /sec_met_domain="TIGR02111 (E-value: 1.5e-82, bitscore:
                     275.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAVARDHYHDRHPFNIRMHQGELTPDELRRWILNRFHYQRHIPV
                     KDALVLAKLGTPQLRRMWLRRIEEHDGRAEGEGGIERWLRLGEAAGLDRAELLSGEGVL
                     PGVRLAVDGYVNFCRLRSPLEAVAASLTELSAPGIMRTRIAAFERHYRWIDADGLAYFR
                     TRETQGRQDSGEALGLVLDWARTEADQERAVAALAFKCDVLWSLLDAIEHGERKERV"
     gene            complement(12254..13162)
                     /gene="pqqB"
                     /locus_tag="LUX31_RS29685"
                     /old_locus_tag="LUX31_29685"
     CDS             complement(12254..13162)
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669247.1"
                     /locus_tag="LUX31_RS29685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29685"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_235478371.1"
                     /transl_table=11
                     /translation="MLLHVLGSAAGGGVPQWNCACPGCSGARAHPHWRRRHASLAVQAS
                     DDHWYLINATPDIGDQIEDCPALQPGPGSRRTPIDGLILTDAELDHTLGIARLREAGAG
                     GLELLATDPVREALLTGLRLEAILGPYTPLTWRELPPERPVPLTEDSSLTISAIPVSAK
                     RPRYAAELPVPDGDSWVVALLLTDRANGTTVVYAPALAAWPDALQTAAEQADCVIVDGT
                     FWDDEEPRRTGISTRTATGMGHLPIEGPGGTAERLVPLRARCLYTHLNNTNPLVDPNAP
                     QYKQLADRGIEVAGDGMVIQL"
     gene            complement(13172..13288)
                     /gene="pqqA"
                     /locus_tag="LUX31_RS29690"
                     /old_locus_tag="LUX31_29690"
     CDS             complement(13172..13288)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669248.1"
                     /locus_tag="LUX31_RS29690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29690"
                     /product="pyrroloquinoline quinone precursor peptide PqqA"
                     /protein_id="WP_235478372.1"
                     /transl_table=11
                     /translation="MTESVQQQVDEEAQSWQTPDYVVIETALEVTAYFLSDR"
     misc_feature    complement(13386..13400)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.81"
                     /tool="antismash"
     misc_feature    13440..13457
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.89"
                     /tool="antismash"
     gene            13582..14637
                     /locus_tag="LUX31_RS29695"
                     /old_locus_tag="LUX31_29695"
     CDS             13582..14637
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712691.1"
                     /locus_tag="LUX31_RS29695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29695"
                     /product="PQQ-dependent sugar dehydrogenase"
                     /protein_id="WP_235478373.1"
                     /transl_table=11
                     /translation="MRAFRTIATAAAVAALTTGLLGADSGTASVPSAIRTVSSGWTVPW
                     GLSWLPDGSALVTERDSFKLFKLTRAGTRTEIGKVPNAVTTSGEGGLLGVAVSPNWNSD
                     HYVYLMHSAASDNRIVRMTYDGTSLGGYTVLVTGIAKSKYHNGGRIKFGPDGHLYATTG
                     DAQNSSLAQDRNSLNGKILRMTKDGKPAPGNPFGTLVLSLGHRNPQGITWDAQGRLWEA
                     EFGNSQYDELNLIESGKNYGWPVCEGTCSTAGMTSPKRQWTVSEASPSAVAYADGALYM
                     AALRGERLWRIPVSGTSAGTPTAYYTTQYGRLRTVEKLPGKNSLWLATTNADNNGGEPD
                     GADKVFQVDLQ"
     gene            14737..16374
                     /locus_tag="LUX31_RS29700"
                     /old_locus_tag="LUX31_29700"
     CDS             14737..16374
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116544.1"
                     /locus_tag="LUX31_RS29700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29700"
                     /product="serine hydrolase"
                     /protein_id="WP_235478374.1"
                     /transl_table=11
                     /translation="MSRLDQARARRLRSAVGLGLIAALAGGGCTGPADTSSAAIHKVAA
                     PTSPLPTVPPAQPPPRLTRAKVDAAVDRLDGVVRDAMRRTGVPGVAVGVVHDDEVLYLK
                     GFGERKAGAEGKVGPDTVFQLASVSKPVASTVVAAAVGEKTVGWDDPVVEHSPGFALKD
                     PWVTRHVTLADLFSHRSGLPDHSGDLLEDLGYDRSYILGHLRYEPLAPFRASYAYTNFG
                     LTEAAVAVARAAGTSWENLSADKLYRPLGMDSTSSSFADYEKAGNKAVTHVKQGDTWQA
                     EFVRDADAQSPAGGASSTVRDMTKWLRLQLGNGEFEGRQVVDADALDETHLPHIVSEPP
                     HAPAGRTGFYGLGWNVGYDDQGRLKLGHSGAFALGAATSVTLLPSENLGIVVLTNGAPI
                     GVPEAIVSTFLDTAQTGGPTVDWLTFIGPLIQQAAAGDRSETDYTKPPAPRAPARADGA
                     YTGTYANDFYGPMTVSAQGDDLVMQLGPKKQRFTLRHYDGDTFSYRTTGENAVGLSGVT
                     FGVGSDGRADKVRVENLDTTGLGTFTKK"
     gene            16429..17214
                     /locus_tag="LUX31_RS29705"
                     /old_locus_tag="LUX31_29705"
     CDS             16429..17214
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (18-115). E-value: 5.5e-07.
                     Score: 21.6. Matches aSDomain:
                     nrpspksdomains_LUX31_RS29705_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007382311.1"
                     /locus_tag="LUX31_RS29705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29705"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_235478375.1"
                     /transl_table=11
                     /translation="MTRTPQSDDQSPRPLTGKVVVITGAARGQGAAEAQALTQAGATVI
                     ATDVRPDGVGDCRKLDVSSEADWAALAAELRDTYGDIHGLVNNAGVIQRDRLGDVRPDD
                     FAYVQSVNTVGPLLGIQYLAPLMPPGSSIVNVGSSAALTAYYPVAYTASKWALRGVSKI
                     AATELGPRGIRVNTVHPGYIETEMTATATPAFREAMFRETPLGRSGTVDDIAPLVVFLL
                     SDASSFISGAEIPVDGGLTAHGGVKSVSDAMRPDAPDQS"
     aSDomain        16483..16773
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LUX31_RS29705_PKS_KR.1"
                     /evalue="5.50E-07"
                     /label="LUX31_RS29705_PKS_KR.1"
                     /locus_tag="LUX31_RS29705"
                     /protein_end="115"
                     /protein_start="18"
                     /score="21.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VVVITGAARGQGAAEAQALTQAGATVIATDVRPDGVGDCRKLDVS
                     SEADWAALAAELRDTYGDIHGLVNNAGVIQRDRLGDVRPDDFAYVQSVNTVG"
     gene            17274..17813
                     /locus_tag="LUX31_RS29710"
                     /old_locus_tag="LUX31_29710"
     CDS             17274..17813
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823202.1"
                     /locus_tag="LUX31_RS29710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29710"
                     /product="GNAT family protein"
                     /protein_id="WP_235478376.1"
                     /transl_table=11
                     /translation="MTGLGTVAWPPAPIKTERLVLRESEARDRTAFIELHASPEVHTYL
                     GGPRSRDELEREMPEVPEQWPGSFVVDLDGAMIGQILLRRATEHRRPAAAGKADLGYLF
                     LPSAWGFGYAAEACAAALGWLAGALPGEPVVLTTQTANVSSMRLAAKLGFTEVERFEAW
                     DAEQWLGMRSPVTPSG"
     gene            complement(18338..19375)
                     /locus_tag="LUX31_RS29715"
                     /old_locus_tag="LUX31_29715"
     CDS             complement(18338..19375)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006373993.1"
                     /locus_tag="LUX31_RS29715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29715"
                     /product="SEC-C domain-containing protein"
                     /protein_id="WP_235478377.1"
                     /transl_table=11
                     /translation="MRPDTPAENVDHVAEAARLERTAGLYPEDAEHLLLQASAHLELAG
                     DRPAATALYDRLLQSSDSDSGSGSGSLENPHLVRALKASNLWEYGHEAEARAIIDGVRA
                     EAPRDPAPWVIVAESLESHDELEAAQETFTEAARLLVSDAQEPPYSTHPLLYGRHRVRR
                     MLGVPHDEWDTLADTLHSSSVSLDELHDPKRVWSLGSDNPAELEAEISRLRAELGAFRE
                     ALSRPFPVAVLHWPADELAELVEAYPALADEYPSHEEHLATIEASLRELAASGTANLGI
                     VTGTVPSYEAFAASEGASPGEAELLPQYATTLAARGKAVGWPPQRGAVCWCGSGAAYEG
                     CHGRL"
     gene            complement(19503..20978)
                     /locus_tag="LUX31_RS29720"
                     /old_locus_tag="LUX31_29720"
     CDS             complement(19503..20978)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056678.1"
                     /locus_tag="LUX31_RS29720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29720"
                     /product="beta-1,6-galactanase"
                     /protein_id="WP_235478378.1"
                     /transl_table=11
                     /translation="MIRRRSLLAAAGGTVLGSALATGTARADATIAVTPGTTYGTWEGW
                     GTSLAWWANVFGARDDFADLFFTTKSVTYNGTSLPGLGLNIARYNLGACSWNSVNGESM
                     VASANIPAYKQIEGYWQDWNNEDPTSSAWDWSADATQRAALTKAVARGATTELFANSPM
                     WWMCSNHNPSGASGGGNNLQTWNYRQHASHLAAVALYAKNNWGVNFATVDPFNEPSASW
                     WTATGTQEGCHMDAAVQAAVLPYMRSELDARGLTGVRISASDETNYDVARSTWAAFGSS
                     TKALVNQVNVHGYQGSGGRRDLLYTDVVTTSGKKLWNSETGDSDGTGLTLASNLCYDFR
                     WLHPTAWVYWQVMDPTAGWAMIAYNPSTLQPTTVQTKHYVMAQFSRHIRPGMTILDTGV
                     SYAVAAYDASAKRLVIVAVNTSTSAQTFTFNLSNFTTVTGGSGGLVPRWNTVTGGGGDL
                     YTARSDTYLSGKTVAVPFAAGAVQTLQVDGVTI"
     gene            21189..21950
                     /locus_tag="LUX31_RS29725"
                     /old_locus_tag="LUX31_29725"
     CDS             21189..21950
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007496420.1"
                     /locus_tag="LUX31_RS29725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_29725"
                     /product="class E sortase"
                     /protein_id="WP_235478379.1"
                     /transl_table=11
                     /translation="MWARARRRVMWTCGELLVTLGTVLALLVVHQLWWTNHQAERGAQR
                     EVRALEREWEEPGLPKSGSGSSSGSGSLDSAQQSPDSSSAAESSGPARATNSRSSTHSW
                     SQAYAILSIPRLGLRVPVAEGVSKSRVLNRGYAGHYPGTQQPGQAGNFALAGHRNTHGE
                     PFRYINRLRRGDAVQVETVDAVYSYTVDRTLPQTSARDDGVISPVPRSTVRPAYGYRTP
                     GYYLTLTTCTPEYTSRHRLVVWGRLTSMRPR"
ORIGIN
        1 gaactccgtt cccggcgcga aggtgttctt gtgcttgaag ccgtacgcga gcacttcccg
       61 aggtgtgaag gagcgctgcg ggtcgctcag caggtcctgg acgaagcccg gatcggaggt
      121 gtacgggaac aggccgctgc gcatctccgc gaggtggcgc agggtgatcc ggtcaccgtt
      181 cggtacgccg cgcacgtaac gcgagatcgg gtcgtccagc cggatccggt ggtcgtcgac
      241 gagttcgagc agcgcggtga ccgtgaaggt cttggtctcg ctgccgatcc gtacgaagcc
      301 gtcggtggtc atcgggcggc gggtggcggt gtcggcgacg ccggtcgcgc ggacgtagct
      361 tcccttgccg ggcatccaca ccccgacgac gacaccgggg atgccggcct gtcgacggac
      421 atcctcgatc gccttgtcca gctgtgcggt cacctcgggg ccgaggccgc ccggagggca
      481 gtcgtcctgg tggtgccggt cgatccttgg ggtctggacg gccgctgcgg gagccgctgc
      541 catcgggacc agagcagcac acgccacgaa cagcgttgcg gcgagcatcc ggaggtgtgg
      601 ggtacgtcgc atctgggggt gcctcttcca gtcacggcag tcacgggctc ggacggcaac
      661 atcaccatcg gcggctcgtc gctaacgtcc ccatccgatc gcgtaccggt gagtccactc
      721 gttcggagcc gcgcgggtgg ctgaggcggc cctgccccag ggctgtggcg gggttcgctg
      781 acaactgctg tgggtctcgc ccgcgttgcc cggccgtgcg cacgacctca gcgcggcccg
      841 catccaccgg atcatccggg tgatccggat ctgcgaatgc caaggcgtcc cgtcctcgcc
      901 gaccgtgcct gtccgggagc cggcccgggg gcatcggtcc ccctgctccc cggcgggcat
      961 ggttccgaac gttgtgcgat cgaaccgcgc tgccacaccg aggcgaggcg tacgaggcgg
     1021 aactcgccga ggagtatccc cagaccgacc gccccggcgt ccccgcccgc tccacctgcc
     1081 gtgacgcccc tgctgggcta gcctgggacg aggacgggcc cccgcgtacg gggccacaca
     1141 aaccggggca acgacagcga gccgccgctg acacatcgcg tcgggcgcgt gggaccgggg
     1201 gctcctcctc atcacgccat ttacgtcgga cgtgtccgtg cctacccgtg accccggcca
     1261 tcgtcaccca ccctgacctc cccgcaagga gggaagcagt atgaatcgtc acggacgtta
     1321 cgcactcctc accccgctcc tggcctccgc gctggctatg ccgcctgcga tggccgccca
     1381 ggcggctcct gcagacgagc tgggcgtcgc gctcgccgcg cccttcaacc cgtcgtgcaa
     1441 gttggtgaag gcgccagatg ccccaggcga attcgacctc gtccttgccg ggttcaagcc
     1501 gaggcaggag gtgagaatca gcggccccga gaagttcaca cgtcaggtca acaagcaggg
     1561 ttccttcacc gagcaggacg tgaagaaggg gacgtacacc gcgacagtcc aggtgaagaa
     1621 aaagaaggtg tcggtcccct gcacgaagcc gcccaggtcg ccggccgtcg acatcacaga
     1681 ggcgagcgcg aatctggtca gccccggccg tagccaaagt gtcgactgcc gtaggcgcca
     1741 acgtgcgacg ttcgggggca cgctcaccgg gaagggaacc ggatcggtga agtacgtgtg
     1801 gaccagcagc gacggcaagc gtgctgagcg caccctcaac ttcacgggcc ccactgccac
     1861 ggtcgaacag ttctccgtga cgatcccagc ccgcgagaag cgttcggacc ctcgccccag
     1921 agtgaccgtc cagctcaggg tgcccaagca gcaaggccag gagggagtct cgtcgagcaa
     1981 cgtgacgctc gtcctcaagt gcaggttccc ctcgtgatcg acgtcaggcg gctcgtacgg
     2041 aggctccgta cgagccgcct gacggaggag accggctgct gggggtgagg gccgcacccc
     2101 cagcgcaccc tcacggagaa gaaaccctca acccccgaag ccgtcccgtg ttgtcgaacg
     2161 acccgaagcc caccctcccg gaggcgagcg tcgtgtccac ggccgtcatc agtggccgtt
     2221 tcgagccgtc gacgtagacc gcgatctcgc ccgtgcccgc gcagcgcacc acccgcacct
     2281 tgtgccaggc cgtgtcggtg atggccggcg gggcgcccgt cgtgccgttc cactggtcgt
     2341 cgatgcgtag gcggtcggag tcgtcgacca cgaagatgcc gttgtgcggg tagatcgtgt
     2401 tgtcctggga caggtgggcg taggagaact tcgtgtccga ctggtagtcg aagacgatga
     2461 tcacgtctcg gttcggagtg tcgacggggg tgtctatgcg gacttccgcg tcgatccgta
     2521 cgtcgccgta cgccgccggg cccgccgtca gtaccgcgta ctcgtacggg cggcgcgggc
     2581 ccgggcgctg gaccccggcc tccgcgagga cggcctcgcg gcccgggaag cgccacttgg
     2641 acggggtgac gggagcccag ttccggccgt ccatgacgtg ggtgagctgg gagccggtgg
     2701 tgtcgcagga cgcgaactcg cgcgtgccgg tgatcttcca gatcctgccg ttggccttcg
     2761 acaacaaata caactcacct tcggcgtccc ggccgaagtg caggtccacc cgggggtcct
     2821 cggccaggtc tcgcatcgtg acgcgcttgc cgctcgcgtc gtacagcatc aggtcgtaca
     2881 gctgcgccag ttgcccgctg ccgcgccgca tgtccttggt gtcggcgaag agcagacgtc
     2941 cgtcgacgat gtccccgaag acgtatttgc cgcgcagtgc gggcaagtca ctgccccggt
     3001 agacgaagcc gccgactacc gcccggccga cgtcggaggt gcagtcccag tcggcgggcg
     3061 ggtcgtggtc gtaggcgacc acggggtaga cgtagccgta cttctcgtcg tcctcgggga
     3121 gcgggaggat ctggtcgcag gggtcggtgg ccgtcttgtc gaagacgaac gggccttcgc
     3181 gttcgctcca gccgaagttg tcgcccgcgc gcacctcgta gaccgactcg acggcgtgct
     3241 ggccgatgct gccgacgtac atacggtggc tgcccgccgg gtcccagctg aagcggtgcg
     3301 ggtcgcgcag gccgtacgcg tagatctcgc ccagcgctcc gggagtggcg gtgaacgggt
     3361 tctgcgccag gattccgtac ttgccgttcg cgctgttcgt gcctcgcggg tctatgcgca
     3421 ggatcttgcc gtgcgggagg gagagggtct gcggctcggt gttccttacg ccctggccgc
     3481 cgtcgccgac tgccaggtag agcagaccgc ggtcggggtc gtggggcagg gccgtcgggt
     3541 tgaagtcgat ctgctggatg ccgtggatcg tgcccgcgaa accgatgcgg aggatttcgc
     3601 ggcgggtgcc gctgaaggtg tccgccgagg ggtcggcggc ggtccactcg gtgacgatgc
     3661 cgtggtagac ggtggaggcc tgctggcggt agtcgggtac ggccgtggtg gcggaggcca
     3721 gttcggtgtg cacggtgtag aagcggccgt tgcggcggaa gtcggggtcg aaggtgacga
     3781 aaccgaagcc ctggcccaga ccccggctgg cgaagaacgc gggggagaag gtggcggcga
     3841 tgtccaggta gagcgcgggg ctgctgccgt cctttaccag gtacagcttg ccgtttaggt
     3901 cgggcaccgc ctttcggccc gagcggtcgg ggagttcgct gaggtagttg atgcgggcct
     3961 gccgcatcag ccggggatcg gtgaccgggc cgggcggcgg atcggtcttc gggaaggagg
     4021 cgtactcctc cacggtcagc ccgatgccgg aggcggcggg gcgctcgggg atggggtcgg
     4081 tgagggggcc ggtggcagcc gccgcgagcg ctctgccggg gagtgcgacc agggccgaca
     4141 gcagcagggc cagggcgatc agaaggatca gaggggcgtg ggctccgggt ctggtgccgg
     4201 gagatgtggc catgcgtacg tcactactcc tatgtcgacg tgggccgtca gcgggcggcc
     4261 atcaggcggt actgggcccg tatccggtcg ccgcccaccg cgctgtccag gaacatcagg
     4321 ctgtccatgc ggcagtcgca gggattgcgt tcgacggtgt tctgcgggaa gctgccgccg
     4381 atcttgatgc cccgggggtc ggtgggtgag gtgcggtgcg ggcccggggc cgcgaggtcc
     4441 caggggtcgc cggggacggt gtaggagccg tccagcggcc ggccgttgcg gtacagcgcc
     4501 atcgcccccg tgtcgaagtc gaaggtggcg gccaggaaga cccactcgcc gatcggcagc
     4561 agcgtgcgcc agtcctggga tgcggcgaac gtctgcgaag ccgctccgtc gacgcgccgg
     4621 cccagggcta cgagtttcag ctcgccgttc acctcgatga tctccagcag gccccgcacc
     4681 gcgtggccgt cggagtcacc cgacagcact ccggccaggc ccacggcacc gtaacggtcg
     4741 tccggggcgg ccgtgttggt gttgagggcc gggttcgggc cgctcatctt gaaccagccc
     4801 atcaccgtca tcccctcaac ccctttgaac gcccggagag ttggcacgcc ggacggcccg
     4861 tacacccccg ccttccagtc gtcgttgccc ttcgcgtccg gggtgatctg ccgtacctgg
     4921 agcgaggtcc ggctgccccg gtgcgctccg tcgtccgtgc gcatccgcgc cccgccgccg
     4981 atcaggtcga tgtcggtacg ggagaagccc aggtcacgtt cgcgcgccgg gttgccgcgg
     5041 accgggtgct cgaagtcgta gtacgccgcc aggtgggggc gtagggaggg gagtacgctc
     5101 ccttctcctc ttcctccgcc tgcgggtgcc gctgctgtgg tggccagggc ggtcagcagt
     5161 gcggcgactg ctgccgcgag cgtgttccgt ctgctgcgca tctacgttct ccttggagtc
     5221 atcggcgtgc gggcctgccg cccagataca gctcgcccag ctgtgggtcc gcgagcaact
     5281 cccgtgccgg gcccgcgata tggacccggc cgaggtcgag gacacagccg gtgtcggcgg
     5341 cctccagggc gcgccgcgcg ttctgttcga ccagcagtac ggcggtcccc gcgtcccgca
     5401 tccggacgat ctgctcgaag accaccccgg tcgccttggg atcgagcccc atcgacggct
     5461 cgtcaaggag cacgacccgg ggctcgacca tcagcgaacg cgcgaactcc acctgcttct
     5521 gctgcccgcc ggagagcagc ccggccaggc tcgtccaccg ctcggccacg accgggaaca
     5581 actcccgtac gaagtcggcc cgttcggcga cgagcgcctt gtcccgcagg gtgtagccgc
     5641 cgagcaggac gttctcggcg accgtcatct ccctgaacac gctgtggcct tggaggacat
     5701 gggcgactcc ggccgccagc atccgctgcg gtccacggcc ggtgacgtcc tcgccgtcga
     5761 cgaggatccg gcccgagcgt ggggtgagga gaccgctggc caccttcaac acggtggact
     5821 ttcctgcccc gttgggcccg accaggcaga cgatcgcccc ggccggtacg cggaccgtca
     5881 gcccgcgcag gaccagcgcc gcccggccgt atccggcgcg gatgtcgtcg agttcgagaa
     5941 ggaaggccgg gtcggtgccg gagctggccc ccgagcccgg gtcggtgtgc gcgtcagacg
     6001 ccaaggtatg ccccgagtac tcgttcgtcg gactggatca gggagggcgg gccctgtgcg
     6061 atcggcctgc cgcggtcgaa cacgacgacg tggtcactga ggctcatgac catgtccatg
     6121 ttgtgctcga cgatcaggaa cgtccgtccc tcggcgttga gttcgcgcac caggtcgccg
     6181 atgcggtcga tgagcgccgg gttgaccccg cccgccggct cgtccagcag gatcagctcc
     6241 ggctcgctgg tcagtacgcc cgccagctcc agcaacttct gctgccccca ggagagttgg
     6301 cgggcctcgg cctgctccag gtgctcgatg cccatccggg tcagccagta acgggcccgc
     6361 tcggtctccg cacgcgtgcc cgagcgtccg agctgtccgg tgagaccgtg cggccggacg
     6421 gcggccagga ggttgtccag cacggtcatc cgggggaaga cccggcagag ctggaaggaa
     6481 cgcccgatgc cggcgcgggc gatccggtgc gggggcctgc ccgtgaggtc gcgtcctcgg
     6541 tacgtgacgc gaccggagtc cgggcggatc atcccggtga cacagttgaa gaaggtcgtc
     6601 ttgcccgaac cgttgggccc gatcagggcg ttgaccttgc cgtggtggaa ggtcacgctg
     6661 gccgagtcga gtgcggtgac tccgccgaag gccttggtga gcccggtggt cgcgaggctc
     6721 ggctcgggct ccgcgtcgga ctccgcgtcg ggctccacct cgggtgccct gtcaggtgcc
     6781 gcttcgttca ctgttcctca cctccgtcgt gtcgcgcccg tcggtctcct cgaactcccc
     6841 gccccgctcc cgcagttcgg ccgcggtcac ctcccgtatg gaggcgtcgc cggtccggcg
     6901 gaaccggccg agcagggcgc cggcggccgg gatgacgccg tccggcatga acgtcacgac
     6961 gacgccgagg agcagccccg ccacgaccag atgcagaggt gtgtccccgt actcgacctt
     7021 ggagtactcc agggcgtacc cgacgatcag cgctcccagc aacggcccgt acaactggcg
     7081 tacgccaccg agcaacgcca tcagcaccat gtacgacccg ctgaggatgg agaactggaa
     7141 gaccgggtcg aggtcgccga accacagggc gtacaacccg ccggccagcg aggtgaaggc
     7201 ggcggagacg acgaagacca ccagcttgta cgtgaacgtg gggatgccga gcgactgcgc
     7261 cttgtcctcg tcctcgcgga tcgccttcag gcccatgccg aaccgtgagc ggtcgatgac
     7321 ccaccagacc agcagggcca gcgcgagcag ggagaggaag aggaagtaga aggtgcggtg
     7381 gtgctcggca cgcagcatgc cggggaaggg ccggggtacg accaggccgc gcgagccgcc
     7441 ggtgagggag gcccagctct ggaagaccag cagcaggatg aggacgaggg cgatggagac
     7501 gatgacgaag gaggcaccgc gtacccgcag ggcggcgtag ccgaccggga cggcgagcgc
     7561 cgccaccagc acggcggcca cgaacagcgc ggcgaagggc gggagttcgc ccttggcgac
     7621 cagcagtccg gtcccgtacg ccccgagtcc ggcgaacgcc ccatgtccca gggagacata
     7681 gcccgtgaag ccgccgacga agttccagga ggtggacagc accgcgtagt tgaggatggc
     7741 gatgcccacg gtgatctcgt aggggctcgg ggccatggac gggaaggaga gcgccacggc
     7801 ggctgccagg agcaggacgc cgagatggac gtaccgggga tggacgagtc tggacctgaa
     7861 gtcagaagaa tcagaaccgt tgcgcaagcc gccccccgaa gaatccctgc ggcctgacgg
     7921 ccagcgtggc gaagagcgcg acgtagaaga cggtctgcgc ccaggtggtg gacagttcca
     7981 gttgcagcag gctctgcagg atgcccagcg tcatggcggc gatggcggcg cccggcacac
     8041 tgccgagtcc gccgacgacg atgatggcca tcagcgggcc gatccagtgc cagtgcagcg
     8101 aggggtagat ggtggtgtcg agggcgagtg ccgtgccgcc gacggccgcc gtggcgagac
     8161 cgaggccgaa cccgtaaccg gcgatccggt cggtgtcgat gcccaacagc cgggcggcgt
     8221 ccgggtgttg gatggtggcg cgcagggcct ggccgaaccg gctgtgcttc atgaggaggt
     8281 agaggccgag cagggcgagt gcggccatgc cgaaggcgat cagcttcacc accgccacgc
     8341 gtgccccgag gaactcgatg ctcgcggagc tgtagccgag ccggacccgg cgctgggtgc
     8401 cgctgaacgc gtacccgagc agcccctcga tgaccagcgc caccgcgaac gtgagcagca
     8461 cggacatcat ggtgagcgtc gccgggcgga gccgggtcaa gagcagccgt tgcagggcga
     8521 cgcccgcggc gaagaacagg ggcacggtga cgaccagggt gaggagcggg tcgacgccgg
     8581 tctcccggtg cgcgaaccag gcgaggtagg cggccaggat cagaaaggcg gagtgggcga
     8641 tcatcacgac gcgcatcacg ccgaagtaga gggtgaggcc cgccgccagg agggcgtaca
     8701 gcccacccag cagcacgccg aggacaaggc tctggaagac gaggctcgcg gagggcacgc
     8761 cggcctcacc actccggctt cggatagacc agaccggttt ccttctgcgc ctcggggagc
     8821 acgatctgga tctcgccgcc gacccactgc tggatcatgt gcgcgctctg cggccggccc
     8881 ttgtcgtccc acttcaacgg gcccacgacg gtgtccactt gattgccgcg gagccactcc
     8941 accagcttgc tctggcagtc cgggtcctgg gaggcgcact gggcggcctc gacggcggcg
     9001 gccaccacct gaccggtcgt gtaggcgttg gcctcgtcct cctccggcgc cttgccgaac
     9061 tgctcggtgt acttctcgac gaactccttg ttggacgggt agtcggcctt ctgggtgtag
     9121 ccggtgggcg cgaggatgcc ctcggtcttg tcgccgatgg ccttggcgaa ctccggctgg
     9181 gtgggcgcgg tggagaaggc ggccaacttc ggctggtagt cgagctgttg gagggcgacg
     9241 atcaggttga cgccgtcctg gtactgggtg ccgcccacca ccatgtcggc cttcgagtcg
     9301 gcgatctggg cggcgatgct gccgaagtcg gtggtgttgg gcgggtagac ctcgtcggcg
     9361 acggtcctga cgccgccctt ctccagcttc tccttcagcc cgtacgcggt tccctgggcg
     9421 aaggggtcgt ccatggcggc gtacgcgacc gtcttgggac gctcgctcgc cggcatggcc
     9481 aggatgtggt cggccaggag gttgtagtgg tcgtcggcga cggccggagc ggcgtagaag
     9541 aggttcttga agccctgctc gaagacctcc ggggccgcgc ccgccggttc gacgaagagc
     9601 atcccgtact cctcggccag ccgcgcggac gggacgacga gccgggtgga gaacggcccg
     9661 aagagcaggt cgacctcgtc tctgccgatg agttgctcgt agtcggagac gacgcggtcg
     9721 gcgttggact ggtcgtcgag gatcttcaac tcgacctcgc ggcccagcag tccgcccttg
     9781 tcgttgacga tcgtcgccca ggccttgtag ccccgttcga cacccttgcc gggttcggag
     9841 aagtcgccgg tgagcggtaa ggagacaccg atgacgatgg ggtcgtcggc ggagtcctgg
     9901 gaaccggcgc ccgagccgca ggcactggcg gcgagtaaca gggcgagggt gccggcggtg
     9961 atccctgctt gtctacggcc ttgtttgcgg tgcgttctgg tcatcgcttg acacccctcg
    10021 tgacttccgt gtggtggcga tcgagcccgc ggtagacgta gtgcggggcg tcggtcctcg
    10081 acgctcgcga caaggtgcgt acgagagcgt ggtcggggga gagcgcgcag gcggggtcgg
    10141 tgcgggcggc gtcaccggtg agcgcgtggg cctgacagcg gcagccgccg aagtcgatct
    10201 cgcggcgggg acagccaccg cagggtccgg tcaccatcca ctcggtgccg cgatagcgct
    10261 cgaaggccgg ggaactggtc cagatccact ccagggaccg gtcgcgtacg ttcggtacgt
    10321 cgtccgggcc cagcaggtcc cgggacgcgg ggcagggcag gacggcgccg tccggggcga
    10381 cggtcagcga caccgcgccc cagccgccca tgcacggctt cggcaccccg tcgaagtggt
    10441 ccggtatgac ccacaccagc tcggtggtgc ccgccagttg ctcccgccgg cgctcgaccg
    10501 cctcccgggc gcgggacagc tggtcgcggg tgggcagcag cgcggtgcgg ttgcgcaggg
    10561 cccacccgtg gaactggacg ttggccagct cgatccgctc ggcaccccag gccacaccca
    10621 ggtccacgat gtcgtcgacg gcgtcgaggt tgtcgcggtg cagaacgacg ttgaggccca
    10681 gcggcagacc cgcgtcccgt acgagaccgg cggcccgttc cttcgctccg aacgaccggt
    10741 gaccgccgat ccggtccgac gccaccggat ccgcgtgctg caccgacagc tgcacgctgc
    10801 gcagtccggc ggacacgagc gcggacatcc tcgccgcgct caacccgacg ccactggtga
    10861 ccagttgggt gtagatcccg gctccctcgg cagcggcgac gacagccgtg agatcgcggc
    10921 ggagcagcgg ctcgccaccg gagagatgcg tggttacgac gccgaggtcc gccgcctgcc
    10981 ggaacacgtc ggcccattcc tcggcggaga gttcgtgtga acggcgcgtg agttccaggg
    11041 ggttggagca gtaggggcag tgcagcgggc aggcgtgggt gagttcggcc agcagggccc
    11101 agggaggcgg cggagccgta tccggaggtg ggctcgtcat ctcagccagc cctcctcgcg
    11161 tacccggtcc aggaaccggg gtacctcctc cgccacgggg gcgcccggga agcgtgccgc
    11221 caacgcgtcg acgatctcgc cgacctgtcg gtgcccgtcg cagagccgca ggacatccgc
    11281 cgcccggccg ctgaggacca ctacccgctc cggcaggacc aacagttccg cctggcgcac
    11341 ccggtcgtgg cggagcacca ccgagcgcgc cagcgccggc cgccacccgg tcccagccaa
    11401 agtcccagtc ccagtcccag tcaccgtcat acgcgctcct ttcgctcacc gtgttcgatc
    11461 gcgtcgagca gcgaccacag cacgtcgcac ttgaaggcga gggccgccac ggcacgctcc
    11521 tggtcggcct cggtgcgggc ccagtccagg acgaggccca gtgcctcgcc gctgtcctgt
    11581 cggccctggg tctcgcgagt acggaagtac gcgagcccgt cggcgtcgat ccaccggtag
    11641 tgacgctcga acgcggcgat gcgcgtgcgc atgatgcccg gcgcggacaa ctcggtgagg
    11701 gacgccgcga cggcctccaa cggggagcgg agccggcaga agttgacgta tccgtccacc
    11761 gccagccgta cgccgggcag tactccctcg ccggacagca gctcggcccg gtcgagcccg
    11821 gcggcctcgc ccagccgcag ccaccgctcg atgccgccct ctccctcggc ccggccgtcg
    11881 tgctcctcga tccgccgcag ccacatccgg cgcagttgcg gggtgcccag cttggccagg
    11941 accagggcgt ccttgacggg gatgtgccgc tggtagtgga accggttgag gatccagcgg
    12001 cgcagctcgt caggggtcaa ctccccttga tgcatacgta tgttgaaggg gtgacggtcg
    12061 tggtagtggt cgcgggccac ggctctcagc cgatcctcga agtgccgatc ctcgaagtgc
    12121 cgatcctcga agtgccgatc ctcgaagtgc cgatcctcga agtgccgatc ctcgaagtgc
    12181 cgatcctcga agtgccggtc cgcgaagtgc cggtcctcga agcccctcgc ggcacccaag
    12241 ccgctgtctg tgctcacagt tggatcacca ttccgtctcc ggccacctcg atgccccggt
    12301 cggccagctg cttgtactgc ggtgcgttcg gatcgacgag gggattggtg ttgttgagat
    12361 gggtgtagag acagcgggcg cgaagtggca ccaggcgctc ggcggtgccg cccggtccct
    12421 cgatcgggag gtgccccata ccggtcgcgg tgcgggtgga gatgcccgtg cgccggggct
    12481 cctcgtcgtc ccagaacgtg ccgtcgacga tcacgcagtc ggcttgctcg gcagcggtct
    12541 gcagagcgtc gggccaggcg gccagcgcgg gggcgtagac gaccgtcgtc ccgttggcgc
    12601 gatcggtgag aagcagggcc acgacccagg aatcaccgtc gggcacgggc aactcggccg
    12661 cgtaacgggg gcgtttggcg gagacgggga tcgcgctgat cgtgagggac gagtcctcgg
    12721 tgagcggtac gggccgctcc gggggcagtt cgcgccaggt gaggggggtg tacgggccga
    12781 ggatggcctc caggcgcagc ccggtgagca gtgcctcgcg tacggggtcg gtggcgagca
    12841 actccagtcc gccggcgccg gcttcgcgca gccgggcgat gccgagggtg tggtcgagtt
    12901 cggcgtcggt caggatcagc ccgtcgatcg gggtccgccg cgaaccggga ccgggctgca
    12961 gggccgggca gtcctcgatc tggtcgccga tgtcgggggt ggcgttgatc agataccagt
    13021 ggtcgtcgga cgcctgtacg gcgagagagg cgtggcggcg gcgccagtgc gggtgtgcac
    13081 gtgccccgga gcaaccggga cacgcacagt tccactgggg tacgccaccg cccgccgcgc
    13141 tgccgagcac gtgcagcagc acggcggcgg gctaacggtc gctcaggaaa tacgcggtga
    13201 cctccagcgc ggtctcgatg accacgtagt cgggggtctg ccagctctgc gcctcttcgt
    13261 cgacctgctg ctgtacggat tcggtcatgt gccgtacctg ccttccgagg ggggaacctg
    13321 tggtgcagca tcgccagcat ctgccagccg ggtcaatggg tcggcggcaa agtgatccga
    13381 tctctagttg gctgaaaatg cgaaccccaa ggtcggctgc tgtcgggtct gttggcaaat
    13441 atgctgttga gatggtaatg gcaaagggat tcgtcaggtg aaggtatgaa cctttggctt
    13501 taaccgtcct tggccctcga ccacatacct cctaccttcc ggagggctct ccccgacacc
    13561 cccacagcga ggagttcgcc catgcgcgca ttccgaacca tcgcaacggc cgctgccgtg
    13621 gccgccctca ccaccggtct cctcggcgcc gacagcggca ccgcctcggt cccgtcggcc
    13681 atccgaaccg tctcgtccgg ctggaccgtt ccctggggcc tgagctggct gcccgacggg
    13741 tcggcgctcg tcaccgaacg ggactccttc aagctcttca agctcacccg ggcgggcacg
    13801 aggaccgaga tcggcaaggt gcccaatgcc gtgaccacca gcggcgaggg cggtctcctc
    13861 ggcgtcgcgg tctcaccgaa ctggaacagc gaccactacg tctacctcat gcactcggcg
    13921 gcctccgaca accgcatcgt ccggatgacg tacgacggca cctcgctcgg cggctacacg
    13981 gtcctcgtca ccggcatcgc caagagcaag taccacaacg gcggtcgcat caagttcggc
    14041 ccggacggcc acctctacgc caccacgggc gacgcgcaga acagcagcct cgcccaggac
    14101 cggaactccc tcaacgggaa gatcctgcgg atgacgaagg acggcaagcc cgcacccggc
    14161 aacccgttcg gcacactcgt cctctccctc ggccaccgca acccccaggg catcacctgg
    14221 gacgcccaag gcaggctctg ggaagccgag ttcggcaaca gccagtacga cgagctcaat
    14281 ctgatcgagt ccggcaagaa ctacggctgg ccggtctgcg agggcacctg ctccaccgcc
    14341 ggcatgacca gccccaagcg gcagtggacc gtcagcgagg cctccccgag cgcggtcgcg
    14401 tacgccgacg gagccctgta catggcggca ctgcgcggcg agaggctgtg gcgcatcccg
    14461 gtcagcggca ccagcgccgg cacccccacc gcgtactaca ccacccagta cggccgactg
    14521 cgcacggtgg agaagctccc cggcaagaac agcctgtggc tggccaccac caacgccgac
    14581 aacaacggag gcgagccgga cggcgcggac aaggtgttcc aggtcgatct gcagtaggac
    14641 gccggccggc cgtaaccggg tggtgcagta ggcggcgggt cccccgaatg gctcgccgat
    14701 gcgacaggcg tcggggctgg gccttcactg gagagcatgt cccgcctcga ccaggcgcgc
    14761 gcccggcgcc ttcgctccgc tgtgggcctg ggcctgatcg cggccctggc cggcggcggc
    14821 tgcacgggcc ccgccgacac ctcctccgcc gccatccata aggtggccgc cccgacgtcg
    14881 ccgctgccca ccgtcccgcc ggcccagccg ccgccgcgcc tcacacgggc caaggtcgac
    14941 gcagcggtgg accggctcga cggagtggta cgggacgcca tgcgcaggac cggtgtgccg
    15001 ggggtcgccg tcggtgtcgt ccatgacgac gaggtgctgt atctgaaggg cttcggcgaa
    15061 cggaaggcgg gcgcggaggg caaggtcgga cccgacaccg tcttccagct cgcctcggtc
    15121 tccaagccgg tcgcctcgac ggtggtcgcc gcggccgtgg gcgagaagac cgtcggctgg
    15181 gacgacccgg tcgtcgagca cagtcccggc ttcgccctca aggacccctg ggtcacccgc
    15241 catgtcacgc tcgccgacct gttctcgcac cgcagcgggc tgcccgacca ctccggggac
    15301 ctcctggagg acctcggcta cgaccgctcg tacatcctgg ggcatctgcg gtacgagccg
    15361 ctggctccgt tccgcgccag ttacgcgtac accaacttcg ggctgaccga agccgcggtc
    15421 gccgtcgcgc gggcggcggg caccagctgg gagaacctgt ccgccgacaa gctgtaccgg
    15481 ccgctgggca tggactccac cagctcctcc ttcgccgact acgagaaagc cgggaacaag
    15541 gccgtcaccc atgtgaagca gggcgacacc tggcaggccg agttcgtacg ggacgccgac
    15601 gcccagagcc cggcgggcgg ggccagctcc accgtccggg acatgacgaa gtggctgcgc
    15661 ctgcaactcg gcaacggcga gttcgagggg cggcaggtcg tcgacgccga cgcgctggac
    15721 gagacgcacc tcccgcacat cgtctccgag ccgccgcacg cgccggcggg caggaccggg
    15781 ttctacgggc tcggctggaa cgtcggctac gacgaccagg gcaggctgaa actcggccac
    15841 tccggcgcct tcgcgctggg cgcggccacc agtgtcacgc tgctgccctc ggagaacctc
    15901 ggcatcgtcg tcctcaccaa cggcgcgccc atcggcgtac cggaggcgat cgtcagtacc
    15961 ttcctcgaca ccgcgcagac gggcgggccc acggtcgact ggctgacgtt catcggcccg
    16021 ctcatccaac aggcggcggc gggcgaccgc tccgagaccg actacaccaa gcctccggca
    16081 ccgcgcgcac cggccagggc ggacggcgcc tacaccggaa cgtacgccaa cgacttctac
    16141 ggcccgatga ccgtgagcgc ccagggcgac gacctcgtca tgcaactggg gccgaagaaa
    16201 cagcggttca ccctgcggca ctacgacggc gacaccttca gctaccgcac cacgggcgag
    16261 aacgccgtcg ggctgtccgg cgtgaccttc ggcgtcgggt ccgacggacg cgccgacaag
    16321 gtccgggtcg agaacctcga cacgaccggc ctcggcacct tcaccaaaaa atgagcccca
    16381 gcccgccggg cggtctcccc tttacccccg gcggctacct tgtccgccat gacgcgcacc
    16441 ccacaaagcg acgaccagtc cccccgcccc ctcaccggca aggtcgtcgt catcaccggc
    16501 gccgcccgag gccagggcgc cgcagaggcc caagccctta cgcaggccgg agccacggtc
    16561 atcgcaaccg acgtacgccc ggacggagtt ggagactgcc ggaagctcga cgtctccagc
    16621 gaggccgact gggccgccct cgccgccgaa ctccgtgaca cctacggcga catccacggc
    16681 ctcgtcaaca acgccggcgt cattcagcgg gaccgcctcg gcgacgtacg tccggacgac
    16741 ttcgcgtacg tccagtcggt gaacaccgtc gggccgctgc tcggcatcca gtacctcgcg
    16801 ccgctgatgc cgccgggctc gtccatagtg aacgtcgggt cgtccgccgc gctcaccgcg
    16861 tactaccccg tggcgtacac cgcgagcaag tgggccctgc gcggggtttc gaagatcgcg
    16921 gcgaccgagt tggggccgcg aggcatccgc gtcaacaccg tgcacccggg ctacatcgag
    16981 accgagatga ccgcgaccgc cacccccgcc ttccgggagg cgatgttccg cgagacgccg
    17041 ctcgggcgca gcggcacggt cgacgacatc gcgcccctcg tcgtcttcct gctctccgac
    17101 gcgtcgtcgt tcatcagtgg agcggagatc cccgtggacg gaggcctcac cgcgcacggc
    17161 ggggtcaagt ccgtctcgga cgcgatgagg ccggacgcgc cggaccagtc gtagtcgacg
    17221 ccgacccgac gccgacccga cgctccgtca ggcgtgcgat aggttcgtcc gccatgaccg
    17281 gactcggaac cgtcgcctgg ccacctgccc cgataaagac cgaacggctc gtgctccgcg
    17341 agtccgaggc ccgggaccgt acggcgttca tcgaactgca cgcctcgccg gaggtgcaca
    17401 cctacctcgg cggtccccgg tcgcgtgacg agctcgaacg cgagatgccc gaggtgcccg
    17461 agcagtggcc cgggagcttc gtcgtcgatc tcgacggagc gatgatcggc cagatcctgc
    17521 tcaggagagc gacggagcac cgccgcccgg cagccgccgg gaaggccgat ctcggctacc
    17581 tcttcctgcc gtccgcgtgg ggattcgggt acgcggccga ggcgtgcgcg gcggcactcg
    17641 gctggctcgc cggcgcgctt cccggcgagc cggtggtgct caccacccag accgccaacg
    17701 tcagctcgat gcgtctcgcg gcgaagctgg ggttcaccga ggtggagcgg ttcgaggcgt
    17761 gggacgccga gcagtggctc ggcatgcggt ccccggtcac gccgtcgggc tgagccgcca
    17821 ttacgccgtc ccaccgatgt cccgtcagac cggcacaaac acgaggtcac catacgtccc
    17881 agtgtcccgg cgtcccaccg ggcgccgatt ccttgccggg cgccgaagcc tcctgccagc
    17941 gtcgccatcg ttcgcgtcgc cggactggaa ctggaagggg aacaccaccg tgaaacgact
    18001 acgccgtatc tgtctcgccc tggccctcac aacgggcctg tcgctcacca ccgccggcgt
    18061 ctcgacggcg gcacccgagg ccgcggccgc ctgcccgggt cttcctggtc ggtccgtcgg
    18121 attttctgta ctacatcccc aacgagaccg tctacttcaa gctgtggcgg accggggacg
    18181 gcatcgccac catcaaccgg tcggcctgca acaagaccga gtacgcgctg accaatggcc
    18241 acatccgtag gtggcccggc ggcggggcca acgtctacac ctggagggcg gacggggtgc
    18301 ttccccacag gggagggaag caccccgtca gaccgaccta cagccgcccg tgacacccct
    18361 cataagccgc ccccgaccca caccagcaaa ccgctccccg ctgaggaggc caccccacag
    18421 ccttcccccg ggccgccagc gtcgtcgcgt actgcggcag cagttccgcc tcccccggag
    18481 acgccccctc cgaggccgcg aaggcctcgt acgacggcac cgtccccgtg acgatcccca
    18541 ggttcgccgt gccggaggca gctagctccc tcagcgaggc ctctatcgtc gcgaggtgct
    18601 cctcgtgcga ggggtactcg tccgccaggg ccgggtacgc ctccaccagc tccgccagtt
    18661 cgtccgccgg ccagtgcagt accgccaccg ggaacgggcg ggacagcgcc tcccggaacg
    18721 cgcccagttc cgcccgtagc cgggagatct ccgcctccag ctccgccggg ttgtccgagc
    18781 cgagggacca gacccgcttc gggtcgtgca gctcgtccag cgacaccgac gacgagtgca
    18841 gcgtgtccgc cagggtgtcc cactcgtcgt ggggcacgcc cagcatccgg cgtacgcggt
    18901 ggcggccgta caacaacgga tgcgtcgagt acgggggttc ctgcgcgtcc gagaccagca
    18961 gacgggccgc ttccgtgaac gtctcctgcg ccgcctccag ctcgtcgtgc gattccaggg
    19021 actccgcgac gatcacccag ggcgccgggt cgcgcggggc ctcggcgcgg acgccgtcga
    19081 tgatcgcccg ggcctccgcc tcgtggccgt actcccacag gttcgaggcc ttcagggccc
    19141 ggacgagatg ggggttctcc agggagccgg agccggaacc ggagtcggag tcggaggatt
    19201 ggagcagacg gtcgtacagg gccgtcgcgg cggggcggtc gccggccagt tccaagtggg
    19261 ccgaggcctg caggagcagg tgttcggcgt cctcgggata gaggccggcg gtccgctcca
    19321 ggcgggccgc ttcggcgacg tggtcgacgt tttccgcagg cgtgtcgggg cgcatgagat
    19381 caccgtactg ccgacgaccg acaaagaaga ggggcggccg aggagcggtc accgtgcggg
    19441 gaggtgccgg gaacggcgcc tcccctcagc agtggctcag cgctcgccgc tacgcccggc
    19501 cctcagatcg tcaccccgtc cacctgcaac gtctgcaccg cccccgccgc gaacggcacc
    19561 gccaccgtct ttccgctcag atacgtgtcc gagcgggccg tgtagaggtc gccgccgcct
    19621 cccgtcaccg tgttccagcg cgggaccagc ccgcccgaac cgcccgtcac cgtcgtgaag
    19681 ttggacaggt tgaaggtgaa ggtctgggcc gaggtggacg tgttcacggc cactatcacc
    19741 aggcgcttcg cgctcgcgtc gtacgccgcc accgcgtagc tgacccccgt gtcgaggatc
    19801 gtcatgcccg ggcggatgtg ccggctgaac tgggccatca catagtgctt cgtctggacc
    19861 gtggtcggct ggagcgtgct cgggttgtag gcgatcatcg cccagcccgc cgtcgggtcc
    19921 atgacctgcc agtagaccca ggccgtgggg tgcagccagc ggaagtcgta gcagaggttc
    19981 gacgccaggg tcagcccggt gccgtcgctg tcgcccgtct ccgagttcca cagcttcttg
    20041 ccggacgtcg tcaccacgtc cgtgtagagg aggtcccggc ggccacctga cccctggtag
    20101 ccgtgcacgt tcacctggtt caccagggcc ttcgtcgacg agccgaaggc cgcccaggtc
    20161 gagcgggcca cgtcgtagtt cgtctcgtcc gaggccgaga tcctgacccc cgtcaggccc
    20221 cgggcgtcca actcgcttct catgtacggg agtacggccg cctgcaccgc cgcgtccatg
    20281 tggcagccct cctgcgtacc ggtggccgtc caccagctcg ccgagggctc gttgaacggg
    20341 tccaccgtcg cgaagttcac gccccagttg ttcttcgcgt acagcgccac ggccgccaga
    20401 tgcgaggcgt gctggcggta gttccaggtc tggaggttgt tgccgccgcc cgaggcgccc
    20461 gacgggttgt ggttcgaaca catccaccac atcggagagt tagcgaacag ctcggtcgtc
    20521 gccccgcgcg ccaccgcctt cgtcagcgcc gcccgctgcg tcgcgtccgc cgaccagtcc
    20581 caggccgagg acgtcgggtc ctcgttgttc cagtcctgcc agtagccctc gatctgcttg
    20641 tacgccggga tgttggccga cgccaccatg ctctcgccgt tgacactgtt ccagctgcac
    20701 gcgccgaggt tgtagcgggc gatgttcagg cccaggccgg gcagcgaagt cccgttgtac
    20761 gtcaccgact tggtggtgaa gaagaggtcc gcgaagtcgt cccgggcgcc gaacacattc
    20821 gcccaccagg cgagcgaggt gccccacccc tcccaagtcc cgtacgtcgt accgggggtg
    20881 accgcgatgg tggcgtcggc tcgcgcggtg cccgtggcca gggcactgcc gaggaccgtg
    20941 ccccctgccg cggccagcag ggatctgcgt cggatcatgg cttctccgtc cggatactga
    21001 cttgtcccgt tcatgccatc aggaagcatc aggcgtggtg ggcgaggttg tcgagagttg
    21061 tgacacccct ttctaaaacc actggacaaa gggggctcac ggggagcgga cggacaggcc
    21121 tggctacttg gcggggtctg ccctatcgtg cgggccggcg tccccatcgt cgcgaaggag
    21181 gcgtacgcat gtgggctcgg gctcgtcgtc gcgtgatgtg gacctgcggc gaactcctcg
    21241 tcaccctcgg taccgtcctc gcgctgctcg tcgtccacca gctgtggtgg accaaccatc
    21301 aggccgagcg gggagcccag cgggaggtgc gggcactgga gagggagtgg gaggaacccg
    21361 gcctcccgaa gagcggctcc ggatccagtt ccggctccgg gtccctcgac tccgcacagc
    21421 agtcgcccga ctcctccagc gccgccgagt cgtccggccc cgcccgcgcc accaactccc
    21481 gttcctccac ccatagttgg tcccaggcgt acgccatcct cagcatcccc cgcctcggcc
    21541 tccgcgtccc cgtcgccgaa ggcgtcagca agtcgcgcgt cctcaacagg ggttacgccg
    21601 gccactaccc cggcacccaa cagccgggcc aggcagggaa cttcgccctc gccgggcacc
    21661 gcaacaccca cggcgagccc ttccggtaca tcaaccgcct gcggcgcggc gacgccgtcc
    21721 aggtcgagac ggtcgacgcg gtctactcgt acaccgtcga ccgcacgctc ccccagacct
    21781 ccgcccggga cgacggcgtg atcagtcccg taccccgctc caccgtcagg ccggcctacg
    21841 gctaccgcac ccccggctac tacctcaccc tcaccacctg cacccctgag tacacgtccc
    21901 gccaccgtct ggtcgtgtgg ggcaggctca catcgatgcg cccccgctga gtcagaggct
    21961 tcctgtataa cgaacagaac gaacagcagg acaaacgact gtgcgagaag cgactgtgtg
    22021 agaggagggc gtggacatga tccggagctg caatccggtc gtccggttga acccgcgtgc
    22081 cgccgccgc
//
