LOCUS       NZ_CP089312            21041 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. GQFP chromosome.
ACCESSION   NZ_CP089312
VERSION     NZ_CP089312.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GQFP
  ORGANISM  Streptomyces sp. GQFP
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8306813)
  AUTHORS   Zhu,J.
  TITLE     Complete Genome Sequence of Streptomyces lacrimifluminis strain
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8306813)
  AUTHORS   Zhu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-DEC-2021) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Dongchuan Road No.800, Shanghai
            200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4; canu v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 109.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:27:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,499
            CDSs (total)                      :: 7,422
            Genes (coding)                    :: 7,228
            CDSs (with protein)               :: 7,228
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 156 of 194
            Pseudo Genes (internal stop)      :: 7 of 194
            Pseudo Genes (multiple problems)  :: 35 of 194
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:04:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2975768
            Orig. end                         :: 2996809
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089312.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21041
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="12"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21041
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21041
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11041](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11041)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(652..1140)
                     /locus_tag="LUX31_RS12850"
                     /old_locus_tag="LUX31_12850"
     CDS             complement(652..1140)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611299.1"
                     /locus_tag="LUX31_RS12850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12850"
                     /product="SigE family RNA polymerase sigma factor"
                     /protein_id="WP_235474910.1"
                     /transl_table=11
                     /translation="MMRGADATLHAFVEGRRTALFRSAYLLCGNRDEAEDLVQTTLVKV
                     VLGARRYGRLDNLEAYARQTLVNTFIAGRRRFWRREHAYGELPETPVEAADNDTGLMVR
                     AALAKLAPKQRAVLVLRYWEDLSVNDTADLLGMRVSTVKSHTARGIAAMRAAVREEHV"
     gene            complement(1278..2057)
                     /locus_tag="LUX31_RS12855"
                     /old_locus_tag="LUX31_12855"
     CDS             complement(1278..2057)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437947.1"
                     /locus_tag="LUX31_RS12855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12855"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_235474911.1"
                     /transl_table=11
                     /translation="MTISIGNTGTNAGTDWNAWQESWDRQQEWYLPDREERFRVMLDMV
                     EALVGPAPRVLDLACGTGSITARLLDRFPGATSTGVDLDPALLAIAEGTFAGDDRVTFV
                     TADLKDPQWAGGLPYDSYDAVLTATALHWLHSDPLADLYGRIAEVVRDGGLFMNADHMI
                     DDSTPRINAAERALRHARMDQAKQNGVVDWAQWWQLAAQDPVLAGPTARRFEIYGEHAE
                     GDTPSAEWHARVLRDKGFAEVRPVWCSPSDTLLLALK"
     gene            2173..2802
                     /locus_tag="LUX31_RS12860"
                     /old_locus_tag="LUX31_12860"
     CDS             2173..2802
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="LUX31_RS12860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12860"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_235474912.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNTEEPARGKDTLTSTDAVRDLFGANQQAARR
                     ATDADVTRFRSVRARLRAVFEAADTGDETLSVDLLNSLLLEFPVSPQISGHDFRDDDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCEAPPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRSEKTGLAAESAQRSSASGER"
     gene            complement(2706..3164)
                     /gene="sodX"
                     /locus_tag="LUX31_RS12865"
                     /old_locus_tag="LUX31_12865"
     CDS             complement(2706..3164)
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491260.1"
                     /locus_tag="LUX31_RS12865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12865"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_235474913.1"
                     /transl_table=11
                     /translation="MPELSQESAHGSERGSEHGEVAKLFGWVEVTGPSMVPTLYHGDFL
                     VVRYGGRVRAGEIVVLRHPFQQDLLVVKRAVERREGGWWVLGDNSFAGGDSTDYGTVPH
                     DLILGRVRFRYRPLKPGQRSPLALLRWALSAARPVFSDRSASRRLRAR"
     gene            3309..3704
                     /gene="sodN"
                     /locus_tag="LUX31_RS12870"
                     /old_locus_tag="LUX31_12870"
     CDS             3309..3704
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="LUX31_RS12870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12870"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_164409275.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQDKIAAN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPELHQLVNDTLKALSAAKA
                     STDPATGQKALDYIAQIDKIFWETKKA"
     gene            complement(<3864..4332)
                     /locus_tag="LUX31_RS12875"
                     /old_locus_tag="LUX31_12875"
                     /pseudo=""
     CDS             complement(<3864..4332)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889358.1"
                     /locus_tag="LUX31_RS12875"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="LUX31_12875"
                     /product="class I SAM-dependent methyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTEPAAATDRTRLAESAYGTDRHLAARQALYRWQTPRHDLPGIAA
                     GQLRDVRGRVVDVGCGNGRFVRRLREHRPAHTVLGLDIAPGILSGVPGPVAVADVTRLP
                     LASGSVGAALAVQGAGVVARRRF"
     gene            complement(4360..5247)
                     /gene="ppk2"
                     /locus_tag="LUX31_RS12880"
                     /old_locus_tag="LUX31_12880"
     CDS             complement(4360..5247)
                     /EC_number="2.7.4.1"
                     /GO_component="GO:0005575 - cellular_component [Evidence
                     IEA]"
                     /GO_function="GO:0008976 - polyphosphate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006793 - phosphorus metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ppk2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380619.1"
                     /locus_tag="LUX31_RS12880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12880"
                     /product="polyphosphate kinase 2"
                     /protein_id="WP_235474914.1"
                     /transl_table=11
                     /translation="MTPLMSGLKVDYSDHDEPVLIRPDGTPVETWRENYPYAERMERKE
                     YEWHKRLQQIELLKLQSWIKQTGRRLVVVFEGRDAAGKGGTIKRFTEHLNPRGARVVAL
                     EKPTERERGQWYFQRYVEHLPTAGEIVLFDRSWYNRAGVERVMGFCTDDEYRRFTRQAP
                     LFERMLVDDGVDLIKFWFSVSQGEQRTRFTIRQVDPVRQWKLSPMDLASLDRWDDYTAA
                     KVAMFRETDTEQAPWTVVKSNDKKRARVEAMRSVLARFDYTGKDEEVVGSPDPSIVGAA
                     ANLLEAGEDDDGGM"
     gene            complement(5284..5517)
                     /locus_tag="LUX31_RS12885"
                     /old_locus_tag="LUX31_12885"
     CDS             complement(5284..5517)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123531.1"
                     /locus_tag="LUX31_RS12885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12885"
                     /product="hypothetical protein"
                     /protein_id="WP_235474915.1"
                     /transl_table=11
                     /translation="MNLDWSALGQVAAVSLGATVAVVVVFAVGVLGLARVEGARENDGG
                     THALGLAQAGLCFVACAAVVAYGIYLIVPQFH"
     gene            complement(5534..6688)
                     /locus_tag="LUX31_RS12890"
                     /old_locus_tag="LUX31_12890"
     CDS             complement(5534..6688)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006817 - phosphate ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058926.1"
                     /locus_tag="LUX31_RS12890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12890"
                     /product="inorganic phosphate transporter"
                     /protein_id="WP_235474916.1"
                     /transl_table=11
                     /translation="MDHITFLVAVVIVTALAFDFTNGFHDTANAMATSIATGALKPKTA
                     VLIAGVLNIVGAFLSTEVAKTISGGIVDDTLVSPGMIFAGLVGAILWNLLTWLVGLPSS
                     SSHALFGGLIGAVWVGAGADGVHFTKVVEKVLIPALASPLVAGIAALIATYLAYKLTAR
                     ARKDTVTKGFRAGQIASASLVSLAHGTNDAQKTMGIITLTLISAGALGHDAGPPVWVIA
                     SAGLAIGLGTYLGGWRIIRTMGKGLTEIQSPQGFAAETASTAVILTSAHLGFALSTTQV
                     ASGSILGAGLGRRLAEVRWGVAGRMVMAWLITLPAAALVGGVSAGAVRYGGTFGTVVVA
                     LVAVAIAAGIVLAARRNPVHANNVNDTHEVSIKASEPTSVGTAA"
     gene            6808..7590
                     /locus_tag="LUX31_RS12895"
                     /old_locus_tag="LUX31_12895"
     CDS             6808..7590
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998002.1"
                     /locus_tag="LUX31_RS12895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12895"
                     /product="VOC family protein"
                     /protein_id="WP_235479903.1"
                     /transl_table=11
                     /translation="MGIRWTYAFIDRPAALLGPAQAFWTAVTDTRLSESRGEQGEFTTL
                     LPGAGDACVKVQGVDSGDGGAHLDFAVEDVDAFVGSATALGATVVGAYTGWAVLRSPAG
                     QLFCAVPWHGESVRPAVVDGSRLDQVSVDVPPTAYDTEVAFWERLTAWDSLPGSLPEFH
                     VLRPPAGLPVRVLLQRLGTDRPGASAHLDLACADIAATRARHEELGATAVAPFPHWTVM
                     RDPAGGTYCLTGRDPETGGLPNHSHISTSTTAPTGIAP"
     gene            complement(7539..7871)
                     /locus_tag="LUX31_RS12900"
                     /old_locus_tag="LUX31_12900"
     CDS             complement(7539..7871)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674925.1"
                     /locus_tag="LUX31_RS12900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12900"
                     /product="DUF952 domain-containing protein"
                     /protein_id="WP_235474917.1"
                     /transl_table=11
                     /translation="MSELPYILHITERALWEAARARGTYEMSTRGRTLQEEGFIHLSTR
                     AQLPAVADFLYGSYDGPDDLVVLVVDPARLDVPLRYEAPKPGGEEFPHVYGAIPVGAVV
                     DVEMWE"
     gene            complement(7891..8304)
                     /locus_tag="LUX31_RS12905"
                     /old_locus_tag="LUX31_12905"
     CDS             complement(7891..8304)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384635.1"
                     /locus_tag="LUX31_RS12905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12905"
                     /product="YciI family protein"
                     /protein_id="WP_235474918.1"
                     /transl_table=11
                     /translation="MKYLVMVRGTQADYDAQNGKASDEGPTWTDDDIQAMYAYMGAINA
                     DLARTGEFLDGNGLAEPARIRHVTAGKDGGTVITDDPYGASEELMAGYWLLECASLERV
                     TEIAARVTRCPVPDGVPEHPVEIRPVLDDPRDQ"
     gene            complement(8301..8516)
                     /locus_tag="LUX31_RS12910"
                     /old_locus_tag="LUX31_12910"
     CDS             complement(8301..8516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998007.1"
                     /locus_tag="LUX31_RS12910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12910"
                     /product="hypothetical protein"
                     /protein_id="WP_235474919.1"
                     /transl_table=11
                     /translation="MGSEQYDCPVCGQQVATVIRRHKTLGAWVPKWVAGPCRNPECEAY
                     APPAAETEAGPVRAARSGRSEPKERS"
     gene            complement(8578..9162)
                     /locus_tag="LUX31_RS12915"
                     /old_locus_tag="LUX31_12915"
     CDS             complement(8578..9162)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="LUX31_RS12915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12915"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_235474920.1"
                     /transl_table=11
                     /translation="MRKLTYFVACSIDGFIGDESGDASFMYPFVDEQFLEFLKTEYPET
                     ISTGGRRALGLDDLPNRRFDTVVQGRASYEVALKEGITSPYAHLREYVASRTLEESPDP
                     HVEIIAADLVARVRELKAEDGDRGIYLCGGSRLAGELIDEIDELVVKTYPIVLGTGMPM
                     FGSGFEVSEFALDEVRPFRNGVLVRTYSRKG"
     gene            complement(9185..9805)
                     /locus_tag="LUX31_RS12920"
                     /old_locus_tag="LUX31_12920"
     CDS             complement(9185..9805)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973719.1"
                     /locus_tag="LUX31_RS12920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12920"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_235474921.1"
                     /transl_table=11
                     /translation="MGVAIRTADERDRELAVRLLDDAFQNDPVSGWIFPDPAHRRVTHP
                     VLVGAFVDIVLAEGRVDLAEDGSACALWLPMPADGHAEASEGDVQGDEGDEAVRLREAI
                     DPDNERVELLVRLTEEIHPSGSAHEYLWMIGVAPDSQRQGLGAALLQHTLDRCDREGTA
                     AYLEASSARSSTLYERLGFNHIGRPLDLPDGPRMWPMWREPRP"
     misc_feature    complement(9925..9941)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.72"
                     /tool="antismash"
     gene            complement(10001..11041)
                     /locus_tag="LUX31_RS12925"
                     /old_locus_tag="LUX31_12925"
     CDS             complement(10001..11041)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571361.1"
                     /locus_tag="LUX31_RS12925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12925"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_235474922.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7e-58, bitscore:
                     194.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGGPEGQDAALILEQARAVVDPALRGAVDSLPGSMRRVVLYHFG
                     WEHADGTPAAGNAGKAIRPALVLTAAAALGGRRETAVRAAAAVELVHNFTLLHDDVMDR
                     DTTRRHRPTAWTVFGDADAILAGDALQALALGLLAVDPHPASATAAARLASCVVELCEG
                     QHADTAMEKQGPGEVTLAECLAMAEAKTGALIGCACALGALYAGGSAADVEAMDAFGRE
                     AGLAFQLIDDVIGIWGDPSRTGKPAGADLVARKKSLPVVAALASGTPAATELAELYGVP
                     YDESQEGALERTVLAVERAGGRDWAQLQAADRMARAIHELSRAVPDPEAAGGLLSLAEF
                     VTRRTT"
     misc_feature    11228..11242
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.84"
                     /tool="antismash"
     gene            complement(11269..12675)
                     /locus_tag="LUX31_RS12930"
                     /old_locus_tag="LUX31_12930"
     CDS             complement(11269..12675)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="LUX31_RS12930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12930"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_235474923.1"
                     /transl_table=11
                     /translation="MSVGEEIRTEQDKPQQSLGTSAARNLATTTKSVPQMQEISSRWLL
                     RMLPWVNVQGGTYRVNRRLTYSVGDGRLTFVKTGDRVEVVPAELSELPALRSYEDEEVL
                     TELARRCQQREFTPGSEIASFGSPNDEVFLLVHGKVEKIGTGPYGDDAELGMLADGAYF
                     GDQALLDPDALWEYTARAVTTVTVLTLSRQHFEQVTERSDSLSDHLQALRAIPEQAANR
                     YGEKEIDLAAGHVGEADIPRTFVDYEAKPREYELSIAQTVLRIHSRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELINNREFGLLSNCEYDQRLQPHDGVPSPDDLDELLSRRRGTK
                     FLLAHPRAISAIGRELNKRGLVPETIDMSGNRIPTWRGVPIYPCNKIPVTEARTTSIIA
                     MRTGEAEQGVIGLQQAGIPDEIEPSLSVRFMGINEQAVINYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            12980..13213
                     /locus_tag="LUX31_RS12935"
                     /old_locus_tag="LUX31_12935"
     CDS             12980..13213
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008745667.1"
                     /locus_tag="LUX31_RS12935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12935"
                     /product="hypothetical protein"
                     /protein_id="WP_235474924.1"
                     /transl_table=11
                     /translation="MAGFLDRAKEQAQRGLTQGKQKLDEVQTQRAGSDLLKKLGAAYYA
                     ERRGSGSPDATQRALQALESHIAVNGDAFLRQ"
     gene            13331..13921
                     /locus_tag="LUX31_RS12940"
                     /old_locus_tag="LUX31_12940"
     CDS             13331..13921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006142330.1"
                     /locus_tag="LUX31_RS12940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12940"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_235474925.1"
                     /transl_table=11
                     /translation="MAPPMSAGSFLDRLREEGVTVVEVGDWPHHNRNHKGPWGPVHGVM
                     IHHTVTKGSEHTVELCRDGYAELPGPLCHGVITKDGCVHLVGYGRANHAGLGDDDVLRA
                     VIAEKLLPPDNEANTDGNRHFYGFECENLGDGEDPWPPAQLDAIEKVAAALCRHHGWTE
                     RSVIGHLEWQPGKIDPRGFSMQWLRERVRDRLK"
     misc_feature    14006..14024
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.58"
                     /tool="antismash"
     misc_feature    complement(14007..14025)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.49"
                     /tool="antismash"
     gene            14110..14979
                     /locus_tag="LUX31_RS12945"
                     /old_locus_tag="LUX31_12945"
     CDS             14110..14979
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380963.1"
                     /locus_tag="LUX31_RS12945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12945"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_235474926.1"
                     /sec_met_domain="PALP (E-value: 2.1e-18, bitscore: 65.5,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPTPLQELTDPRFARHHLRLLLKRDDLIHPDLVGNKWRKLVPN
                     LDAAAGRPILTFGGAYSNHLRATATAGRLLGLPAIGIVRGQELAARPLNPSLAHCTANG
                     MRLHFVDRSTYRRKTDPDTLAAIRREAGADDAYVVPEGGSNALAVRGCRALGEELRGHA
                     DVVAVACGTGGTLAGLAAGLAPDQRALGIPVLKGGFLDAEIRALQDLAFGGARGSWTLD
                     HRFHFGGYARTPPELHAFADDFEARHDVPMEPLYVAKMLYGLVALAEEGAFPRGTTVAA
                     VITGRPFP"
     gene            complement(14992..16587)
                     /locus_tag="LUX31_RS12950"
                     /old_locus_tag="LUX31_12950"
     CDS             complement(14992..16587)
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006380975.1"
                     /locus_tag="LUX31_RS12950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12950"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_235474927.1"
                     /transl_table=11
                     /translation="MHVMPLLLLVAGSAAIAAAARRTPVPPPLLLVAAGLVFAYVPGVP
                     DYALDPHVVLPLMLPPLLYTAAVDSSYLDLRAQLRPVALLSVGYVLFATLVVGWAAYLI
                     VPGLPLTAALVLGAVVAPPDAVAATAIARRVGLPSRVTTILQGESLVNDATAITAYRVA
                     LAAAVGEGATWAGGIGEFLLAAVGGIGIGLILMMPIHWLRTHLKEALLQNTLSLLIPFA
                     AYAVAEEVHASGVLAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLEGLGAYEGVDAAWYAIAVFLVVVVTRFVWVYPGTFVPRLLSARIRDREPNPTW
                     KGAFVISWAGMRGVVSLAIAFSIPLTMEGGEAFPERNLVLFLTFTTVIGTLVVQGLTLP
                     PLIRLLKLPGRDAQAETLAEANAQAQASRAAQQRLEGLLEDDRNALPPPLADRLRTVLE
                     RRQNAVWERLGAVNPVTGETVDDTYRRLSREMISAEREVFVRLRDARHIDDEMLRTLLR
                     RLDLEEAAAFREPE"
     gene            16678..16938
                     /locus_tag="LUX31_RS12955"
                     /old_locus_tag="LUX31_12955"
     CDS             16678..16938
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="LUX31_RS12955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12955"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_235474928.1"
                     /transl_table=11
                     /translation="MKQCTHADALPVPEPKPKSETCPECLAAGTHPVQLRLCLDCGHVG
                     CCDSSPMRHATGHHKETGHPVMRTFEPGESWRWCFVDHVLV"
     misc_feature    17127..17140
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.89"
                     /tool="antismash"
     misc_feature    complement(17132..17145)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            17276..17689
                     /locus_tag="LUX31_RS12960"
                     /old_locus_tag="LUX31_12960"
     CDS             17276..17689
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="LUX31_RS12960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12960"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_053744517.1"
                     /transl_table=11
                     /translation="MSQFAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLIDDSLEVTVSAPTTDGHAPARDTFAWTV
                     LSALAGQVDSTVAEDKTVSISLYKKRGAGPGPA"
     gene            17686..18813
                     /locus_tag="LUX31_RS12965"
                     /old_locus_tag="LUX31_12965"
     CDS             17686..18813
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030133.1"
                     /locus_tag="LUX31_RS12965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12965"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_235474929.1"
                     /transl_table=11
                     /translation="MRNGDGPVRDEERGTRELPAAGSGGPDGPRDTADAISGVAGISGI
                     PEQARPHPEDDPSEAGFMDDGQLDREGAVQSAPLEGPSEVSPVRADARIRGRSTGGTMS
                     EHERDDAQGAPQTAQATQHSPTDRSGARALFIELRALEDGSVAYAELRNRLVRMHLPLV
                     EHLARRFRNRGEPLDDLTQVATIGLIKSVDRFDPDRGVEFSTYATPTVVGEIKRHFRDK
                     GWAVRVPRRLQELRLSLTTATAELSQRHGRSPTVHELAEKLGISEEEVLEGLESANAYS
                     TLSLDVPDTDDESPAVADTLGAYDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNM
                     TQSQIAQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(18842..19288)
                     /locus_tag="LUX31_RS12970"
                     /old_locus_tag="LUX31_12970"
     CDS             complement(18842..19288)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983568.1"
                     /locus_tag="LUX31_RS12970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12970"
                     /product="hypothetical protein"
                     /protein_id="WP_235474930.1"
                     /transl_table=11
                     /translation="MSVEQNPSPETPESVGPRPLRLTAAAVLAGLEGLALVVGGVLILG
                     LGITGDADDRQQAVTGGVTLVVLALLPLLAARGLLGRRSWSRGPAVITQIMALPVAYNL
                     LQADSMAIPGGIVLGVVAVTALVLLVNQETTRALGIRGPGSASE"
     gene            19471..20439
                     /locus_tag="LUX31_RS12975"
                     /old_locus_tag="LUX31_12975"
     CDS             19471..20439
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006127486.1"
                     /locus_tag="LUX31_RS12975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12975"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_235474931.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLTHALASEMKLEAVTTEYRGHARD
                     LGRQAAESKDIDLVVALGGDGTVNEVVNGLLHNGPDPDRLPGLAVVPGGSTNVFARALG
                     LPNDAVEATGVLLDALREERERTVGLGMAKGTPGTEDESVPGRWFTFCAGLGFDAGVIG
                     RVEQQRERGRKSTHSLYLRQAARQFLGEANRRHGTITLEQPGEDPVTDLVLSIVCNTSP
                     WTFLGNRPVYASPKASFDTGLDVLGLSRMSSAAVARYGMQLLTSSPERGPHGRHATSLH
                     DLTDFTLHSKAPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    complement(20529..20538)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(20700..20715)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    20703..20714
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            20759..21016
                     /locus_tag="LUX31_RS12980"
                     /old_locus_tag="LUX31_12980"
     CDS             20759..21016
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="LUX31_RS12980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_12980"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_006380970.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQATA"
ORIGIN
        1 tcttcaggta gagcgtggcc atgaggtact caccccaggt gcggcggttg tccatgaaga
       61 cgctgccgtg cttccagccc ttccggactt cgaggacgtt gccgttcggc agcctctcga
      121 aggtgcactc ctgcccgtcc tccttgcccg gaagcgaaca aggactcttc cagctcgggc
      181 tccgaacctt gctgaacccg ttgatcaccc ggaggtagcc gaccccgccg tccctggtga
      241 ccgtgtagga gccgtagtac ttgccgaagg ggccggcctc cgaatgctcc ggctcccgga
      301 acaggacgta gtccatgtcc acttcacgga tcgcaccgac accggggggc agcagcttcg
      361 cgaactcggc cgccagggcg gtggcccggc cgggaggctt gatcgtcccc gtgttcgcgg
      421 cgccgccacc gccctcgtcg tacgtcagcc acccgggccc cgccaccacc cccgccgcga
      481 ccccggccgc cgcgacgacc gtcaccgcgc tccaccgtcg ccgccgcacc cgcgcggccc
      541 gcgcgaacac cgcctccgta ccggcccccg tcggcgcgga gacccctccc acggcccgcc
      601 cgagaagctc gcgcccctcc agccaggtct cgacctcgtc gatgtcggtg ctcatacgtg
      661 ctcctcccgc accgcggccc gcatcgccgc gattcccctg gccgtgtggc tcttcaccgt
      721 gctcacccgc ataccgagca ggtccgcggt gtcgttgacg ctgaggtcct cccagtagcg
      781 cagcaccagc accgcccgct gcttgggcgc gagcttcgcc agtgccgcgc gcaccatcag
      841 ccccgtgtcg ttgtccgccg cctcgacggg cgtctccggc agttcgccgt acgcgtgttc
      901 gcgccgccag aagcgccggc gccccgcgat gaaggtgttg accagcgtct ggcgggcgta
      961 ggcctccaga ttgtccagcc gcccgtatct gcgcgccccg aggacgacct tcacgagcgt
     1021 cgtctggacg agatcctcgg cctcgtcacg gttgccgcag agcagatagg cgctccggaa
     1081 cagcgccgtg cgtctgccct ccacgaaggc gtgcagagtc gcgtccgcgc cccgcatcat
     1141 ccttcccccc ttcccggtcc cctggtcgag gaccgcctca cccctaccag tgcgccgggg
     1201 acccgtcgag gacgcggcgc gcacggaaaa ggcggtacgg attctccgta ccgcctccac
     1261 cgcacgcgct gccggggtta cttgagggcg agcagcaggg tgtccgaggg cgagcaccac
     1321 acgggacgca cctccgcgaa ccccttgtcg cgcagcacgc gcgcgtgcca ctcggcggag
     1381 ggtgtgtcgc cttccgcgtg ctcgccgtag atctcgaagc ggcgggcggt cggcccggcg
     1441 aggacggggt cctgggcggc gagctgccac cattgcgccc agtcgacgac gccgttctgt
     1501 ttggcctgat ccatacgtgc gtggcgcagt gcgcgctccg ccgcgttgat ccggggcgtg
     1561 ctgtcgtcga tcatgtggtc cgcgttcatg aacagaccgc cgtcgcggac gacctccgcg
     1621 atccggccgt agaggtccgc gagggggtcg ctgtgcagcc agtgcagggc ggtggcggtc
     1681 aggacggcgt cgtacgagtc gtacggcagc ccgccggccc actgcgggtc cttgaggtcg
     1741 gccgtgacga aggtgacgcg gtcgtcgccc gcgaaggtgc cctcggcgat ggcgaggagc
     1801 gccgggtcga ggtcgacgcc ggtgctggtg gccccgggga accggtcgag gagccgggcc
     1861 gtgatacttc ccgtgccgca cgcgaggtcg agcacgcgcg gggcggggcc gacgagggcc
     1921 tcgaccatgt cgagcatgac cctgaaccgt tcctcccggt ccggcaggta ccactcctgc
     1981 tgccggtccc agctctcctg ccaggcattc cagtcggttc cggcgtttgt accagtgttg
     2041 ccaatactga tggtcatcga agcccctcgg tcggccgctc actttgaaca catgcgtaat
     2101 accctggaag caatgtcagc cgttacttcc gcccacaccg acgaccatag aacgcgcccg
     2161 taaggactac aagtggaact ggcctattac tcggactacg ccgtgcgtct cgtcaacacc
     2221 gaggaaccgg cgcgcggaaa ggacacgttg acctcgaccg acgcggtgcg cgacctcttc
     2281 ggcgccaacc agcaggccgc ccgccgcgcc accgacgccg acgtgacccg gttccgctcc
     2341 gtacgggccc ggctgcgcgc cgtcttcgag gcggcggaca cgggcgacga gacgctctcg
     2401 gtggacctgc tgaactcact cctgctggag ttcccggtga gcccgcagat ctccgggcac
     2461 gacttccggg acgacgacgg gcgcccgctg tggcacatgc atctcgccga ccacccgtcg
     2521 aacgcgaccg cgggctacgc ggccatcgcc gcgatgggac tggccttcca cctcaccgag
     2581 tacggcgtgg accgcctggg cctgtgcgag gcgccgccct gccgcaacgc ctacctcgac
     2641 acctcgacga accgctcccg ccgctactgc tccgaccgct gcgcgacccg ggccaacgtg
     2701 gccgcctacc gcgcccgcaa acgcctggag gcggaccggt ccgagaagac gggcctcgcg
     2761 gccgagagcg cccagcgcag cagcgccagc ggcgaacgct gaccgggctt cagcggccgg
     2821 tagcggaacc ggacccggcc caggatcaga tcgtgcggca cggtcccgta gtcggtgctg
     2881 tcgccgccgg cgaaggagtt gtcccccagc acccaccaac cgccctcacg gcgctccacg
     2941 gcccgtttga cgaccagcag gtcctgctgg aacggatggc gcagaacgac gatctccccg
     3001 gccctgaccc tgcccccgta gcgcaccacg agaaaatcgc cgtgatacag cgtgggcacc
     3061 atcgagggcc cggtcacttc aacccatccg aagagcttcg cgacctctcc gtgctcactc
     3121 ccgcgctcac tcccgtgtgc gctctcctgc gacagctccg gcatcccggc acctccccgg
     3181 ttccatcctc caccagtccc agtctgacgc cctacttttg tcctaagccc atgggggcac
     3241 tcgcgaaaac ccctctctca gggagtaatg tccaacctga gaagacgatc acgaggaagg
     3301 aacgctccat gctttcccgc ctgtttgccc ccaaggtcaa ggtcagcgcc cactgcgacc
     3361 tgccctgcgg tgtttacgac ccggcccagg cccgcatcga ggcggagtcg gtgaaggccg
     3421 tgcaggacaa gattgccgcc aacgacgacc cgcacttcca ggcgcgtgcc accgtcatca
     3481 aggaacagcg cgcagaactc gccaagcacc acgtttccgt gctgtggagc gactacttca
     3541 agcccccgca cttcgagaag tacccggagc tgcaccagct ggtcaacgac accctgaagg
     3601 ccctctcggc cgccaaggcg tcgaccgacc cggcgacggg ccagaaggcc ctggactaca
     3661 tcgcccagat cgacaagatc ttctgggaga ccaagaaggc ctgatgcggg ctttcgccga
     3721 aaaggggccg atcgatgtcg accggcccct tttcgctgcc cacgaccgcg tgagcactcg
     3781 tcggtgacga tgacgcgggc ccgctcgacg ggtcgttcct acccggacga gttcctccct
     3841 gttcctgtcc ggcgcggagc acggagcagg tcgctcgcgg cccgctgccg caggtcgtcc
     3901 agttcagcct tgtcacactc gccgttggtc gaggcgaact cgggcccatc agaagcgacg
     3961 acgcgcgaca actcccgcac cctgcacagc cagcgccgcg cccacgctcc ccgaagccag
     4021 cggcagtcgt gtgacatccg ccacggcgac cgggccgggg acgccggaga ggatgccggg
     4081 cgcgatgtcc aggcccagta cggtgtgcgc gggccggtgc tcgcgcagcc gccgtacgaa
     4141 cctgccgttg ccgcagccga cgtcgaccac gcggccccgt acgtcacgaa gctgcccggc
     4201 agcgatgccg ggcaggtcgt gacggggcgt ctgccaccgg tagagcgcct ggcgggcggc
     4261 caggtgccgg tcggtgccgt aggcgctctc ggcgaggcgg gtccggtcgg tggctgcggc
     4321 gggttcggtc acctcggagg catccccgcc gtgggcggtt cacatgccgc cgtcgtcgtc
     4381 ctcgcccgcc tccagcaggt tcgccgccgc gcccacgatg ctcgggtccg ggctgccgac
     4441 gacctcctcg tccttgcccg tgtaatcgaa gcgggccagc acgctgcgca tcgcctcgac
     4501 ccgcgcccgc ttcttgtcgt tgctcttcac caccgtccag ggcgcctgtt cggtgtccgt
     4561 ctcgcggaac atggcgacct tggccgccgt gtagtcgtcc cagcggtcca gggacgcgag
     4621 gtccatgggg ctgagcttcc actgccgtac ggggtcgacc tgacggatcg tgaaacgggt
     4681 gcgctgttcg ccctgggaga ccgagaacca gaacttgatc aggtcgacgc cgtcgtcgac
     4741 gagcatccgc tcgaacagcg gggcctggcg ggtgaagcgc cggtactcgt cgtccgtaca
     4801 gaagcccatg acccgttcca caccggcccg gttgtaccag gagcggtcga acagcactat
     4861 ctcgccggcg gtcggcaggt gttcgacgta ccgctggaag taccactggc cgcgttcgcg
     4921 ttcggtgggc ttctccaggg cgaccacccg ggcgccgcgc gggttcaggt gctccgtgaa
     4981 gcgcttgatc gtgccgccct tgccggccgc gtcccggccc tcgaagacga cgaccaggcg
     5041 gcggccggtc tgtttgatcc agctctgcag cttcagcagt tcgatctgct ggagccgctt
     5101 gtgccactcg tactccttgc gctccatgcg ctcggcgtag gggtagttct cccgccaggt
     5161 ctcgaccgga gtgccgtccg gccggatgag gacgggttcg tcgtggtcgc tgtagtcgac
     5221 cttcagcccg gacatcagtg gtgtcattct gtcggcctcc ccaacgtcgg tgatcggttg
     5281 cggtcagtgg aactgcggca cgatcagata gatgccgtac gcgaccacgg cggcgcacgc
     5341 cacgaagcac agcccggcct gggcgagccc gagcgcgtgc gtaccaccgt cattctcacg
     5401 cgcgccctcg acccgggcga gtccgaggac accgacggcg aagacgacga ccacggcgac
     5461 ggtggccccg aggctcaccg cggcgacctg acccagggcg ctccagtcca gattcatttc
     5521 ggttctccct cgctcacgcg gccgtaccga cgctcgtcgg ctccgacgcc ttgatgctga
     5581 cctcgtgggt gtcgttgacg ttgttcgcgt gcaccgggtt gcggcgtgcg gcgaggacga
     5641 tgcccgccgc gatcgcaacg gcgaccagcg cgacgacgac ggtgccgaag gtgccgccgt
     5701 acctgacggc gcccgctgag accccgccga ccagcgccgc ggcgggcagg gtgatcagcc
     5761 acgccatgac catgcggccc gcgacacccc agcgcacctc cgcgagccgc ctgcccaggc
     5821 ccgcgcccag gatgctgccc gaggcgacct gggtggtcga cagggcgaag ccgaggtggg
     5881 cggaggtgag gatgacggcc gtggacgccg tctcggcggc gaagccctgc ggcgactgga
     5941 tctcggtcag ccccttgccc atggtccgga tgatccgcca gccgcccaga taggtgccga
     6001 ggccgatggc gagaccggcc gacgcgatca cccacaccgg cggaccggcg tcgtggccga
     6061 gcgcgcccgc ggagatcagg gtcagggtga tgatgcccat ggtcttctgc gcgtcgttcg
     6121 tgccgtgcgc gagggagacg agcgaggcgg aggcgatctg accggcccgg aatcccttgg
     6181 tcaccgtgtc cttgcgggcg cgggccgtga gcttgtaggc gaggtacgtg gcgatcagag
     6241 ccgcgattcc ggccaccagc ggtgaggcca gcgccgggat cagtaccttc tcgacgacct
     6301 tggtgaagtg gacaccgtcg gcgcccgcgc cgacccacac cgcgccgatc agcccgccga
     6361 acagggcgtg cgaggaactc gacggcagcc ccaccagcca ggtcagcaga ttccacagga
     6421 tcgccccgac cagcccggcg aagatcatcc cagggctgac gagcgtgtcg tcgacgatgc
     6481 cgccggagat cgtcttggcg acctcggtgg acaggaacgc gccgacgatg ttgaggactc
     6541 cggcgatcag gaccgctgtc ttcggtttca gggcgccggt ggcgatggag gtggccatcg
     6601 cgttcgccgt gtcgtggaat ccgttggtga agtcgaaggc cagggccgtc acgatgacga
     6661 ccgccaccag gaacgtgatg tggtccatgc gttcgatgga agcaagcgca ggcgtattcg
     6721 caacgaactc cgggcaaagg ctgttcctgg aaaaaacgca ggtgacgtgg acgaccgcca
     6781 ccttacgatc accccatgag cactggtatg ggcatccgct ggacctacgc cttcatcgac
     6841 cggcccgccg cactcctcgg ccccgcccag gcgttctgga ccgccgtcac ggacacccgg
     6901 ctctccgaat cccggggcga gcagggcgag ttcacgaccc tgctgccggg cgcgggcgac
     6961 gcctgcgtca aggtccaggg ggtggactcc ggggacggcg gcgcccatct cgacttcgcg
     7021 gtcgaggatg tcgacgcctt cgtcggttcg gcgacggcgc tcggggcgac cgtcgtcggc
     7081 gcgtacaccg gatgggccgt gctgcggtcg cccgccggtc agctgttctg cgccgtgccc
     7141 tggcacgggg agtcggtacg gcccgccgtg gtggacggca gccgactcga ccaggtgagc
     7201 gtcgacgtcc cgccgaccgc gtacgacacg gaggtcgcct tctgggagcg cctcaccgcc
     7261 tgggactccc tccccggctc actcccggag ttccacgtcc tcaggccccc ggccggcctc
     7321 ccggtccgcg tcctcctcca gcgcctcggc accgaccggc caggcgcctc cgcccacctg
     7381 gacctggcct gcgccgacat cgcggcgacc cgcgcccgcc acgaggaact gggggccacg
     7441 gccgtcgccc ccttccccca ctggacggtc atgcgcgacc cggcgggcgg cacgtactgc
     7501 ctgaccggcc gcgaccccga aacgggcggc ctgccgaatc actcccacat ctcgacgtcc
     7561 accacggcac ccaccgggat cgccccgtag acatgcggaa actcctcgcc gcccggcttc
     7621 ggtgcctcgt acctcagggg tacgtcgagc cgcgcggggt ccacgaccag caccaccagg
     7681 tcgtcggggc cgtcgtagga gccgtacagg aagtcggcca cggccgggag ctgggcgcgt
     7741 gtcgacaaat ggatgaagcc ctcctcctgg agggtgcggc cacgcgtcga catctcgtac
     7801 gtgccccgcg cgcgggccgc ctcccacagg gcgcgttcgg tgatgtggag tatgtacggc
     7861 agttctgaca tcaacccaac ctacgggccc ttactggtcc cggggatcgt ccaggacggg
     7921 ccggatctcc acgggatgct ccggtacgcc gtccgggacc gggcagcggg tgacgcgggc
     7981 ggcgatctcg gtgacccgct ccaggctcgc gcactccagg agccagtagc cggccatcag
     8041 ctcctcgctc gcgccgtacg gatcgtcggt gatcaccgtg ccgccgtcct tgcccgcggt
     8101 gacgtgcctg atccgcgcgg gttcggccag gccgttcccg tcgaggaact cgcccgtcct
     8161 ggcgaggtcg gcgttgatcg cgcccatgta cgcgtacatg gcctggatgt cgtcgtcggt
     8221 ccaggtgggg ccttcgtcgg acgccttgcc gttctgggcg tcgtagtccg cctgcgtgcc
     8281 gcgcaccatc accaggtact tcatgaccgc tccttcggct cggaccgccc cgaccgggcc
     8341 gcccgcacag ggcctgcctc ggtctcggcc gccggagggg cgtacgcctc gcactcggga
     8401 ttccggcacg gcccggcgac ccacttcggt acccacgcgc ccagggtctt gtgccgccgt
     8461 atcaccgtgg ccacctgctg cccgcagacg ggacagtcgt actgttcgct gcccataccc
     8521 cagggtattg cggaagccgc cggggcgctc cccgccggtt cggcctcttc tgccgcttca
     8581 acccttcctg ctgtacgtcc gcaccagcac cccgttcctg aacgggcgca cctcgtcgag
     8641 cgcgaactcc gacacctcga agccggagcc gaacatcggc atcccggtgc cgaggacgat
     8701 cgggtacgtc ttgacgacca gctcgtcgat ctcgtcgatc agctcacccg cgaggcgcga
     8761 gccgccgcac aggtagatgc cccggtcgcc gtcctccgcc ttgagttccc ggaccctggc
     8821 gaccagatcg gcggcgatga tctcgacgtg cgggtccggc gactcctcca gggtgcgcga
     8881 ggcgacgtac tcgcgcagat gggcgtacgg gctggtgatg ccctccttca gagcgacctc
     8941 gtagctggcc cggccctgga cgaccgtgtc gaaacggcgg ttgggcaggt cgtccaggcc
     9001 gagggcgcgg cggcccccgg tggagatcgt ctcggggtac tcggtcttca ggaactccag
     9061 gaactgctcg tcgacgaacg ggtacatgaa ggaggcgtcg ccgctctcgt ccccgatgaa
     9121 tccgtcgatc gagcaggcga cgaagtaggt gagctttcgc aagccgttct ctttcggtca
     9181 gggcctaggg ccggggctcg cgccacatgg gccacatgcg ggggccgtcc gggaggtcga
     9241 gggggcggcc gatgtgattg aagccgagcc gttcgtacag cgtgctgctg cgggcactgc
     9301 tcgcctccag ataggcggcc gttccctcgc ggtcgcagcg gtcgagggtg tgctggagga
     9361 gagccgcccc caggccctgg cgctggctgt ccggtgcgac gccgatcatc cacaggtatt
     9421 cgtgggcgct cccggaggga tggatctcct ccgtcagccg cacgagcagt tcgacgcgct
     9481 cgttgtcggg atcgatggcc tcgcgcaagc ggaccgcttc gtcgccctcg tccccttgta
     9541 cgtccccctc gctcgcctcc gcgtggccgt cggcgggcat gggcagccac agggcgcacg
     9601 ccgaaccgtc ctcggcgagg tcgacgcggc cctcggcgag cacgatgtcg acgaaggcgc
     9661 ccaccagtac cggatgcgtc acgcggcggt gcgccgggtc cgggaagatc cagccgctca
     9721 ccggatcgtt ctggaaggca tcgtccaaca gccggacggc cagctcccgg tctctctcgt
     9781 ccgccgtacg tatcgccacg cccatgaccc gcccctttgt cccaaccgcc gttgcttgta
     9841 tggcggttga gcataacggg tggggaagtt gtgacggggc ccgcacaccg tggggatgtg
     9901 cgggacccgt cggccggagc gccggtgcga gtcgtacgga gtcagggccg tacaccccgc
     9961 cacgggttgc tccggggcct caggtggtgc gatgtgtgtc tcaggtggtg cggcgggtga
    10021 cgaactcggc cagggacagc agaccacccg ccgcctccgg gtcggggacc gcgcgggaca
    10081 gttcgtgtat cgcgcgggcc atccggtcgg ccgcctggag ctgcgcccag tcccggccgc
    10141 ccgcccgctc gaccgcgagc accgtccgct ccagcgcccc ttcctggctc tcgtcgtacg
    10201 gaaccccgta cagctcggcc agttcggtgg ccgccggtgt gccggaggcc agtgcggcga
    10261 ccacgggcag ggacttcttg cgggcgacca gatccgcccc ggccggcttg ccggtgcggc
    10321 tcgggtcccc ccatatcccg atcacgtcgt cgatgagctg aaaggcgagc ccggcctccc
    10381 ggccgaacgc gtccatcgcc tcgacgtccg cggccgaacc gcccgcgtac agcgccccga
    10441 gagcacaggc gcagccgatc agcgcgcccg tcttggcctc ggccatggcg aggcactcgg
    10501 cgagggtgac ctccccgggg ccctgtttct ccatggccgt gtccgcgtgc tgcccctcgc
    10561 acagttcgac gacgcaggac gcgagccggg cggcggcggt ggcggacgcc gggtgcgggt
    10621 caacggcgag cagtccgagc gccagtgcct gcagcgcgtc cccggcgagg atcgcgtcgg
    10681 cgtcgccgaa cacggtccag gcggtgggcc ggtgtctgcg ggtggtgtcc cggtccatga
    10741 cgtcgtcgtg cagcagggtg aagttgtgga ccagctccac cgccgcggcg gcccgtacgg
    10801 ctgtctcccg ccgtccgccg agtgccgcgg cggcggtcag cacgagcgcg gggcggatcg
    10861 ccttgcccgc gttgcccgcc gccggggtgc cgtccgcgtg ctcccacccg aagtggtaga
    10921 gcacgacccg gcgcatggac ccgggcagcg aatcgaccgc tccgcgcagc gcgggatcga
    10981 ccacggcccg cgcctgctcc aggatgaggg cggcatcctg cccctccggt ccgccggaca
    11041 cccccgctcc tcccccgtct cccgtccccc gtacgggtac gggggacttc gcctgcctcg
    11101 acggcctcgg caggcccgac tggttcgcct ggcttgcacc cacggccggc cgctcccctg
    11161 ccccggactc cggtgaactc cccgcaggcc actcctccgg actgccgatg gggctccgcc
    11221 tttccggatc cagggtctcg atggtctcga ccgggccgtg gggcggggtc atcgccagcg
    11281 gccgatctcg acgttctcca gcacgccgag ggcgtccggg accaggacgg ccgccgagta
    11341 gtaggccgtc accaggtagt tgatgaccgc ctgttcgttg atgcccatga accgcacgga
    11401 cagactgggc tcgatctcgt ccgggatacc ggcctgctgg agcccgatga ccccctgctc
    11461 ggcctcgccg gtacgcatgg cgatgatcga ggtcgtacgg gcctcggtga ccgggatctt
    11521 gttgcacggg tagatcggca caccgcgcca ggtggggatg cggttgccgc tcatgtcgat
    11581 cgtctcgggg acgagtccgc gcttgttcag ctcacggccg atcgcggaga tcgcgcgcgg
    11641 gtgggcgagc aggaacttgg tcccgcgccg cctgctgagc agctcgtcca ggtcgtcggg
    11701 gctgggcacg ccgtcgtgcg gctggagccg ctggtcgtac tcgcagttgc tgagcagtcc
    11761 gaactcccgg ttgttgatga gttcgtgctc ctggcgctcc ttcagggcct cgaccgtgag
    11821 acggagctgc tgttccgtct ggttcatcgg ctggttgtag aggtcggcca cgcgggagtg
    11881 gatgcgcagc accgtctggg cgatgctcag ttcgtactcg cggggcttgg cctcgtagtc
    11941 gacgaacgtg cgcgggatgt ccgcctcgcc gacgtgaccg gccgcgaggt cgatctcctt
    12001 ctcgccgtac ctgttggcgg cctgctccgg gatcgcccgc agggcctgga ggtggtcgct
    12061 cagcgagtcg gaacgctcgg tgacctgctc gaagtgctgc cgggagaggg tcagcacggt
    12121 gaccgtggtg accgcgcggg ccgtgtactc ccagagggcg tcggggtcga gcagtgcctg
    12181 gtcgccgaag tacgcgccgt cggcgagcat gccgagttcg gcgtcgtccc cgtacgggcc
    12241 cgtgccgatc ttctcgacct tgccgtggac cagcaggaac acctcgtcgt tcgggctgcc
    12301 gaacgaggcg atctccgaac ccggtgtgaa ctcccgctgc tggcagcgcc gggccaactc
    12361 ggtgagcact tcctcgtcct cgtaggaccg cagggccggc aactcggaca gttcggcggg
    12421 gaccacttcc acgcggtcac cggtcttcac gaacgtcaga cggccgtccc ccacggagta
    12481 ggtgagccgc cggttcacac ggtaagtacc accctgcaca ttcacccagg ggagcatgcg
    12541 cagcagccag cgcgagctga tctcctgcat ctgggggacg gacttggtgg tggtggccag
    12601 attccgcgcg gccgatgtgc cgagactctg ctgcggcttg tcctgctccg tgcggatctc
    12661 ttcgcctacc gacataagga actgccctcc cggtcaactc ttaaatgcgc cgacgcgctg
    12721 atccctctcg ggttcgttcc gcatcggacg cctgcgcgca ccagccttcc ccaccgaacg
    12781 cgcccgtgct actacacgaa tgagcgggaa tggatcatct ccggagtggg cacaaagggg
    12841 ttcttcgcca aatcgttcga ccgggcgaac ggaaaagacc tcttctgccg tctccttctc
    12901 cctcctccct ccgtttcggg aacttcaaga tcggaccgac cgtttgagcc tttgacggac
    12961 tacgaacaag gagacaccga tggcaggctt cctggaccgc gcgaaggaac aggcacagcg
    13021 tggcctgaca cagggcaagc agaagctcga cgaggtgcag acccagcggg cgggcagcga
    13081 cctgctcaag aaactgggtg cggcgtacta cgcggagcgg cgcggcagcg gttctcccga
    13141 cgcgacccag cgagcccttc aggccctgga gagtcacatc gcggtgaacg gggacgcgtt
    13201 cctgcgccag tgaccggatc ggctcgcacg ccgtccgaac aattcaccct tgaccgtggg
    13261 attccggtac aagctgcggt acgaggcggt cacgaccggt ggccgtcgcg cagcgcgtaa
    13321 ggagacggtc atggccccac ccatgtccgc gggcagcttc ctggaccggc tcagggagga
    13381 aggcgtcacc gtcgtcgagg tcggcgactg gccccaccac aaccgcaacc acaaaggccc
    13441 ttggggcccg gtgcacggcg tgatgatcca tcacacggtg accaagggca gcgagcacac
    13501 ggtggaactc tgccgcgatg gctatgccga gctgcccggc cctctgtgcc acggcgtcat
    13561 caccaaggac ggctgcgtcc atctcgtcgg ctacggcagg gccaaccacg cgggtctggg
    13621 cgacgacgac gtgctgcgtg cggtgatcgc cgagaagctc cttccgccgg acaacgaggc
    13681 gaacacggac ggcaatcggc acttctacgg cttcgagtgc gagaacctcg gcgacggcga
    13741 ggatccctgg cctccggccc agctcgacgc catcgagaag gtcgccgcgg cgctgtgccg
    13801 ccaccacggc tggacggagc ggtcggtcat cggccacctc gaatggcaac cgggcaagat
    13861 cgacccacgg ggcttcagca tgcagtggct gagggaacgg gtacgggacc gcttgaagta
    13921 gggatttcct tcgcccccgc cgcccctacc cattcccatc ctcgggggct ccgcccccga
    13981 acccccgctc ctcaaacgcg ggaggggctg gatattcagc ccgtccggcg tttgaggaca
    14041 aagggggggt ctgggggcgc agcccccagg gatgggacgg gtaggggcgg cgggggcgaa
    14101 aatggctctg tgtccctccc cacccccctc caagagctca ccgacccccg cttcgcccgc
    14161 caccacctcc gtctgctcct caagcgcgac gacctcatcc acccggacct cgtcggcaac
    14221 aagtggcgca agctggtccc caacctggat gccgccgccg gacgcccgat cctcaccttc
    14281 ggcggcgcct actccaacca cctgcgcgcc acagccaccg ctggccgcct cctcggcctg
    14341 ccggccatcg ggatcgtccg gggtcaggaa ctcgccgccc gccctctcaa cccctccctc
    14401 gcccactgca cggcgaacgg catgcgcctg cacttcgtcg acagatcgac gtaccggcgc
    14461 aagaccgacc ccgacaccct cgccgccatc cgcagggaag ccggcgccga cgacgcgtac
    14521 gtcgtgccgg aaggcggcag caacgccctc gccgtacgcg gctgccgcgc cctcggcgag
    14581 gagctgcgcg gccacgccga cgtcgtcgcg gtcgcctgcg gcaccggcgg caccctcgcc
    14641 ggcctggccg cgggcctcgc ccccgaccag cgcgccctcg gcatcccggt cctcaagggc
    14701 ggcttcctgg acgcggagat acgggccctc caggacctcg ccttcggcgg cgcccgcggc
    14761 tcctggaccc tcgaccaccg tttccacttc ggcggctatg cccgtacgcc ccccgaactg
    14821 cacgccttcg ccgacgactt cgaggcccgt cacgacgtcc ccatggaacc tctctatgtc
    14881 gccaagatgc tgtacggact tgtcgctctc gcggaagaag gcgcgttccc gcgcgggacc
    14941 accgtcgcgg cggtgatcac cggccgcccg ttcccgtgac ggacgtcgcc ctcactccgg
    15001 ctcccggaac gccgccgctt cctccaggtc cagccgtcgc agcagcgtcc gcagcatctc
    15061 gtcgtcgatg tggcgcgcgt cccgcagccg cacgaacacc tcccgttccg cgctgatcat
    15121 ctccctggac agccgccggt acgtgtcgtc caccgtctcg ccggtcacgg gattgaccgc
    15181 gcccagccgt tcccagacgg cgttctggcg gcgttccagg actgtcctga gccggtcggc
    15241 cagcggaggc ggcagcgcgt tgcggtcgtc ctccagcagg ccctccaggc gctgctgtgc
    15301 cgccctggac gcctgggcct gggcgttcgc ctccgcgagc gtctccgcct gcgcgtcacg
    15361 cccgggcagc ttcagcagac ggatcagcgg gggcagcgtc agcccctgga cgaccagtgt
    15421 gccgatgacc gtagtgaagg tcaggaagag caccaggttc cgttccggga acgcctctcc
    15481 gccctccatc gtgagcggga tcgagaaggc gatggccagg gagaccaccc cccgcatccc
    15541 ggcccaggag atgacgaacg cgcccttcca ggtcgggttc ggttcgcggt cccggatccg
    15601 tgccgacaac agccggggca cgaacgttcc ggggtacacc cagacgaacc tggtgacgac
    15661 gaccacgagg aagacggcga tcgcgtacca ggcggcgtcg acaccctcgt atgccccaag
    15721 tccctccagg acgaccggca gttgcaggcc gatcagggcg aagacggccg attcgagaac
    15781 gaaggcaacc attttccaga ccgcctcctc ctggagacgg gtcgcgaaat cgacctccca
    15841 cgcgcgatgg cccagataaa gcgccacgac caccaccgcg aggaccccgg aggcgtgcac
    15901 ctcttcggcg accgcgtacg ccgcgaacgg gatcagcagg gagagagtgt tctgcaacag
    15961 cgcttccttc aggtgcgtgc gcagccaatg gatcggcatc atcaggatca gcccgatccc
    16021 gatgccgccg accgccgcga gcaggaactc gccgatcccg cccgcccagg tagcgccctc
    16081 tccaacggcc gccgcgaggg ctacgcggta cgcggtgatc gcggtggcgt cgttcaccag
    16141 ggactcgccc tggaggatgg tcgtgacccg cgacggcagc ccgacccggc gtgcgatcgc
    16201 cgtcgccgcg acggcgtccg gcggtgccac gaccgcgccg agcaccagcg cggcggtcag
    16261 cggcagcccg ggcacgatca gataggcggc ccagccgacg acgagggtcg cgaagagcac
    16321 gtaccccacc gacagcagcg ccacgggccg cagttgcgca cgcagatcga ggtacgagct
    16381 gtcgacggcc gccgtgtaca gcagcggggg cagcatcagc ggcaggacga catgcgggtc
    16441 gagggcgtag tcgggcaccc cggggacgta cgcgaacacc aggccggccg cgaccagcag
    16501 cagcgggggc gggaccgggg tgcggcgggc cgcggcggcg atggcggcgc tgcccgcgac
    16561 cagcaggagc agtggcatca cgtgcatcgg tctcggccca atctcgtttc ccgccccatc
    16621 cggcacccca tctggattcc gcgcggcttt ccgcgcaccc gtcgtaacct ggcaatcatg
    16681 aaacagtgca cgcatgccga cgcgctgccg gtcccggaac caaagcccaa gagcgagacc
    16741 tgcccggagt gcctggcggc cggtacccat ccggtgcagc tgcgcctgtg cctggactgc
    16801 ggccacgtcg gctgctgcga ctcctcgccg atgcgccacg cgacaggaca ccacaaggag
    16861 accgggcatc cggtgatgcg caccttcgaa cccggcgaga gctggcgctg gtgcttcgtg
    16921 gaccatgtcc tcgtatgacc gcgcggaagc cgcgtatcgt cgtccacccg acctcgcacc
    16981 cgtgtgagca ggggcattgg tgaccggagg cgtactcgtg tgaccctgga tccggacggt
    17041 tcgaccgtct gacgtctggg tacgtcaacc cggcgctcgt tgttcccaat tgggcccgca
    17101 gaacccctag ccactgtgcg tatccgtatg tttactatga gtgacagcaa ggggctgggg
    17161 tcccggggac agaaatgtcg agagcgcggt agcgtcaccg ctgaaccacg tatcgcgtta
    17221 ccccgggggg cgaccctcgg cccccgaaag agcttgtacc accttggagg tgagggtgtc
    17281 ccagttcgca ggcgagcccg cgacccagga cttcgtggaa gtccggctgc cggccgcggg
    17341 tgcctacctg tcggtgctgc gtacggccac ggccggtctc gcggcccgtt tggacttcac
    17401 cctcgacgag atcgaggacc tgcgcatcgc agtggacgag gcctgcgcga tcctgcttca
    17461 gcaggccgtg cccggctccg tactcagctg tgtgttccgg ctgatcgacg actccctgga
    17521 ggtcacggtc tcggcaccga ccacggacgg tcacgccccc gcgcgtgaca ccttcgcctg
    17581 gaccgtcctg tccgccctcg cgggccaggt cgactccacc gtcgccgagg acaagaccgt
    17641 gtcgatcagt ctctacaaga agcgcggcgc gggacccggg ccggcgtgag gaacggggac
    17701 gggccggtgc gggacgaaga gcgcggcaca cgggagctgc ccgcggcggg cagcggcggc
    17761 cccgacgggc cgcgggacac ggcggatgcc atttccggcg tcgccggtat ctccggcatc
    17821 cccgagcagg cccggccgca cccggaggac gacccctcgg aggccggctt catggacgac
    17881 gggcagctgg atcgggaagg tgccgtgcag agtgcgcccc tggaagggcc aagcgaggtc
    17941 tcccctgttc gagctgatgc gcgaattcgg ggaaggtcga cgggcgggac gatgagcgag
    18001 cacgaacgag acgacgcgca gggcgcacca cagacggcgc aggccacgca gcactccccg
    18061 acggaccgca gcggagcgcg tgccctgttc atcgagctgc gcgcgctgga ggacggcagt
    18121 gtcgcgtacg cggagctgcg caaccggctg gtccgtatgc atctcccgct cgtcgagcac
    18181 ctcgcgcgcc gcttccgcaa ccgcggcgag ccgctggacg acctcaccca ggtcgcgacc
    18241 atcggcctga tcaagtcggt cgaccgcttc gacccggacc gcggtgtcga gttctcgacg
    18301 tacgcgaccc cgacggtcgt cggcgagatc aagcggcact tccgggacaa gggctgggcg
    18361 gtccgcgtcc cgcgcaggct ccaggagctg cgcctctcgc tcaccacggc gacggcggag
    18421 ctgtcgcagc ggcacggccg ctcccccacg gtgcacgagc tggccgagaa gctgggcatc
    18481 tcggaggagg aggtcctgga gggcctggag tcggccaacg cctactccac gctgtccctg
    18541 gacgtccccg acacggacga cgagtccccg gcggtcgcgg acacactggg cgcgtacgac
    18601 gaggccctgg agggcgtcga gtaccgcgag tcgctcaagc cgctcctgga ggatctcccg
    18661 ccgcgcgaga agcggatcct gctgctgcgg ttcttcggca acatgacgca gtcgcagatc
    18721 gcgcaggagg tcggcatctc ccagatgcac gtctcccggc tgctggcccg gaccctggcc
    18781 cagctgcgcg agaagctgct ggtcgaggag taatcactga tcgaggagta cccctcaggg
    18841 gctactccga cgcgctgccg ggcccccgga tcccgagggc ccgggtcgtc tcctggttca
    18901 ccagcagcac cagcgcggtg accgccacga cacccagcac gatcccgccc ggaatggcca
    18961 tgctgtcggc ctggagcagg ttgtaggcca cgggcagcgc catgatctgc gtgatcacgg
    19021 ccggcccccg gctccagctg cgccgcccca gcagcccgcg cgcggcgagc agcggcagca
    19081 gcgcgagcac gacgagcgtg acgcctccgg tgacggcctg ctgccggtcg tccgcgtcac
    19141 ccgtgatccc cagcccgagg atgagaactc ccccgacgac cagggcaagc ccctccagcc
    19201 cggcgagcac ggcggcggcg gtcagccgca gtggccgcgg ccccacagat tcgggagttt
    19261 ccggggaggg gttctgctca acgctcacgc aagaagggta tcgctgggac cctacggcgc
    19321 tcggacgcgc ccctaagggg cgcggggaac tgcgcgacca gccacaacgc acccgcagcc
    19381 aaacaccgcg cccccgctca cacccgccaa ctcttactga tccctaacct gccctgggcc
    19441 gagtaccacc gggtaggtac cctgcttcgc atgcgtgcac ttctcgtggt caatccggcg
    19501 gctaccacca caagcgcacg tacgcgcgat gtgctgaccc atgctctcgc gagcgagatg
    19561 aaactcgagg cggtcaccac cgagtaccgg ggccacgcgc gtgacctagg ccggcaggcc
    19621 gcggagagca aggacataga tctggtcgtc gccctcggcg gcgacggaac ggtcaacgag
    19681 gtcgtgaacg gcctcctgca caacggcccc gacccggacc ggctgcccgg cctcgccgtg
    19741 gtccccggcg gctccacgaa cgtcttcgcc cgcgccctcg gcctgcccaa cgacgccgtg
    19801 gaggccaccg gcgtcctgct ggacgccctg cgcgaggagc gggagcgcac ggtgggcctc
    19861 ggaatggcga aggggacgcc gggtaccgag gacgagtccg tgccggggcg ctggttcacg
    19921 ttctgcgccg gtctgggatt cgacgccggt gtgatcggac gggtggaaca gcagcgcgaa
    19981 cgcggcagga aatccacaca ctccctttac ctgcggcagg ccgcgcgcca attcctggga
    20041 gaggccaatc gccggcacgg cacgatcaca ctggaacaac cgggcgagga ccccgttacc
    20101 gatcttgtgc tgtccatagt ctgcaacacg tccccttgga cgtttctggg caatcgcccg
    20161 gtgtacgcgt cgcctaaggc ctcgttcgat accgggctcg acgtactcgg tctcagccgt
    20221 atgtcgtcgg ccgcggttgc ccggtatggc atgcagttgc tcacttcgtc ccccgaacgg
    20281 ggaccccatg gcaggcatgc cacgtccctg cacgacctga ctgacttcac cttgcattcg
    20341 aaggcacctc tgcccctcca gatggacggc gaccaccttg gactgcgaac gagcgtgacg
    20401 ttcacaggcg tacgccgtgc actgcgtgtg attgtgtgag cggaacgggc taaagtcctt
    20461 ccactcgaac gtttaggcca gggtccaccc catggaagta cggctgtgac cgagccgaca
    20521 ccgaggaatc aaaaaaaact ttccggtagg ggttgtatcc gccgctgagg tttgcgagtc
    20581 tctacgtggc gctcgggacg gcccgcaaca ccggccacca cagagagcca gaacccctcc
    20641 tcacttcaca ggaccacatc agtccatctg atgatcggcc cttcacttgt tgagggattc
    20701 gtgaaagcgt tcacattcac aagcaacgtg catgtaatac caaggagagg tagcagccat
    20761 ggactggcgt cacaacgccg tttgccgcga ggaagacccc gagctcttct tccccatcgg
    20821 caacaccggt cctgcgctgc tgcagatcga ggaagccaag gccgtctgcc gccgctgccc
    20881 cgtcatggag cagtgcctgc agtgggcgct tgagtccggc caggactccg gcgtctgggg
    20941 tggtctcagc gaggacgagc gccgcgccat gaagcgccgc gccgcccgca accgggcccg
    21001 tcaggcaacc gcctgacaag ccaccccgta acagcctgag c
//
