LOCUS       NZ_CP089312            12976 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. GQFP chromosome.
ACCESSION   NZ_CP089312
VERSION     NZ_CP089312.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. GQFP
  ORGANISM  Streptomyces sp. GQFP
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8306813)
  AUTHORS   Zhu,J.
  TITLE     Complete Genome Sequence of Streptomyces lacrimifluminis strain
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8306813)
  AUTHORS   Zhu,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-DEC-2021) School of Life Sciences and Biotechnology,
            Shanghai Jiao Tong University, Dongchuan Road No.800, Shanghai
            200240, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 4; canu v. 1.6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 109.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:27:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,499
            CDSs (total)                      :: 7,422
            Genes (coding)                    :: 7,228
            CDSs (with protein)               :: 7,228
            Genes (RNA)                       :: 77
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 194
            CDSs (without protein)            :: 194
            Pseudo Genes (ambiguous residues) :: 0 of 194
            Pseudo Genes (frameshifted)       :: 69 of 194
            Pseudo Genes (incomplete)         :: 156 of 194
            Pseudo Genes (internal stop)      :: 7 of 194
            Pseudo Genes (multiple problems)  :: 35 of 194
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:04:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2120095
            Orig. end                         :: 2133071
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089312.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..12976
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="9"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12976
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12976
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7976](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7976)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    complement(936..950)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(2025..2039)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 21.4"
                     /tool="antismash"
     misc_feature    2025..2040
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    complement(2026..2039)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.38"
                     /tool="antismash"
     gene            complement(2191..2862)
                     /locus_tag="LUX31_RS09190"
                     /old_locus_tag="LUX31_09190"
     CDS             complement(2191..2862)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381030.1"
                     /locus_tag="LUX31_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09190"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_235474292.1"
                     /transl_table=11
                     /translation="MAAQRTGPALPSLGGPRPSYRASVADALRAALVAGELRPGEVYSA
                     PSLAARFGVSATPVREAMLDLVKEGMVDPVPNKGFRVTTVSERQLDEYTHIRSLIEIPT
                     TVGLAATADPAALEALRKDAADSVAAAESGDLIAYVDSDRRFHLGLLALAGNEHLVEVV
                     GDLRKRSRLYGLTALAERGLLTSSAEEHLEILDALLARDAAGVRTAMTRHLGHVRGDWA
                     H"
     gene            complement(2931..3932)
                     /locus_tag="LUX31_RS09195"
                     /old_locus_tag="LUX31_09195"
     CDS             complement(2931..3932)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358096.1"
                     /locus_tag="LUX31_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09195"
                     /product="proline racemase family protein"
                     /protein_id="WP_235474293.1"
                     /transl_table=11
                     /translation="MRSKLVLHAVDSHTEGMPTRVVTGGIGTIPGDTMNERRLWFREHR
                     DDVRNFLMNEPRGHAAMSGAILQPPTRPDCDYGVVYIEVSGYLPMCGHGTIGVATVLVE
                     TGMVPVVEPVTTIRLDTPAGLVVAEVSVEGGAAKAVTIRNVPSFAVELGRKATLADGRT
                     VTYDLAFGGNFYAILPLDEFGLPFERDRKDDILAAGLALMDAINADSPPVHPENPTING
                     VHHVYLAAPGSDATRSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLHQDFLNES
                     FIGTSFTGRLVESVEVAGRPAVVPTITGRAWVTGTAQYLLDPDDPFPAGFVL"
     gene            complement(3974..4873)
                     /locus_tag="LUX31_RS09200"
                     /old_locus_tag="LUX31_09200"
     CDS             complement(3974..4873)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381020.1"
                     /locus_tag="LUX31_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09200"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_235474294.1"
                     /transl_table=11
                     /translation="MGTTAPVPVWRGVLVATALPLNDDLSVNYAAYADHCRWLVENGCD
                     GVVPNGSLGEYQVLTAEERTKVVETAVAAIGGDRVMPGVAAYGSAESARWAAQAKDAGC
                     AAVMLLPPNAYRADERSVLAHYAAVAEVGIDIVAYNNPIDTKVDLTPELLAKLHAAGLI
                     KGVKEFSGDTRRIYQIQELAPELDVLIGADDVLLELATAGAVGWVAGYPNALPRATVEL
                     YRAAVAGDLATALPLYQQLHALHRWDSKVEFVQAIKLSMDIVGRHGGPVRPPRMPLLPE
                     QEKAVREATEKAVALGLA"
     misc_feature    4990..5005
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.8"
                     /tool="antismash"
     gene            complement(5001..6389)
                     /locus_tag="LUX31_RS09205"
                     /old_locus_tag="LUX31_09205"
     CDS             complement(5001..6389)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381018.1"
                     /locus_tag="LUX31_RS09205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09205"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_235474295.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.7e-24, bitscore:
                     84.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1.8e-11, bitscore:
                     43.0, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIVGAGPAGLAAALTAADLGVRVVLLDSGAQAGGQFYRQPAAAL
                     KARRPQALHHAWGTWEKLRDRLAAHVAAGRITHLADRHVWFVEGEFGGSGRFGVHALLG
                     PAQAESETVTADAVLLATGGYEKVLPFPGWTLPGVVTAGGAQAMLKGGLVLPGRTAVVA
                     GTGPLLMPVAAGLAAAGAEVAAYVESTHPADFVRHTATLAANPAKIAEAVQYAAQLLCH
                     KVPVTVRHTVVAAHGTDRVEAVTVAALDPDGRVRPGTERRIACDTLAVGHGMLAHTDLA
                     ETLGCAIDATGDPFVVTDAEQRTDVDGVWAAGEATGIGGAVLALAEGEIAGCSIAARLG
                     GVEPRPADWAAAARTRTRLRKFFAAVDTAYAPPARWVEQVADDTVVCRCEEVTASEVRE
                     AVEELGATDLRTVKLLTRAGMGWCQGRVCATGVAGVAGCSVGVAKRPFAGPVPLGVLAE
                     EPRC"
     misc_feature    complement(6382..6396)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(6493..6807)
                     /locus_tag="LUX31_RS09210"
                     /old_locus_tag="LUX31_09210"
     CDS             complement(6493..6807)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381026.1"
                     /locus_tag="LUX31_RS09210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09210"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_235474296.1"
                     /sec_met_domain="Fer2_4 (E-value: 1.2e-24, bitscore: 85.0,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRQRTPLELARAHPGPPFTVTVDGHETAALPGQTVAAVLWSVGVT
                     SWRSTRGSGAPRGIFCGIGVCFDCLVTVNDRPNQRACLVPAASGDVIRTQEGVGHDELG
                     "
     gene            complement(6804..7976)
                     /locus_tag="LUX31_RS09215"
                     /old_locus_tag="LUX31_09215"
     CDS             complement(6804..7976)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006381043.1"
                     /locus_tag="LUX31_RS09215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09215"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_235474297.1"
                     /sec_met_domain="DAO (E-value: 4e-64, bitscore: 216.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKRLTCDVVVIGAGMVGAACALYLARAGLATLVLDRGPVAGGTT
                     GAGEGNLLVSDKEPGPELDLALLSARLWHDLAAEPGLGGAVEFEAKGGIVVASDAAGMA
                     ALAGFAAGQRAAGIEAETVDAGQLADLEPHLAPDLAGGVLYPQDCQVMPSLAAAQVVRA
                     ARRAGAELRTGTAVTDILCAPDGSVRGVRTAEHGDIHAPAVVNAAGTWGGEVAALAGVH
                     LPVLPRRGFVLVTEPLPPGTVRHKVYAADYVADVASGDAGLQSSAVVESTAAGPVLIGA
                     SRERVGFDRTFSLPVVRRLAAQALALFPVLGSVHAMRAYLGFRPYMPDHLPAIGADPRA
                     PGLYHACGHEGAGIGLAVGTGQLIAQSLAGKRPDLDLAPFRPDRFEEGNQ"
     misc_feature    7978..7994
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 19.62"
                     /tool="antismash"
     misc_feature    7982..7992
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            8181..9542
                     /locus_tag="LUX31_RS09220"
                     /old_locus_tag="LUX31_09220"
     CDS             8181..9542
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006375652.1"
                     /locus_tag="LUX31_RS09220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09220"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_235479850.1"
                     /transl_table=11
                     /translation="MTTGWADTELKDLRPIEQAPYAAERRAALSARFPGERLIVPAGNL
                     KVRANDTHYPFRPSTEYVHLTGDQTVDALLVLEPRADADGHDAVAYLLPRSDRDSGEFW
                     QGAAKGELWVGRRHSLAEAEQVLGLPCRDVREASAELRAAPAVPTRIVRGYDAELEAAV
                     TTDEDRDTELKTVLSELRLVKDDWEIGEMRKAVDSTVRGFVDVVRELATAIATSERWIE
                     GTFFRRARLEGNDIGYGSICAAGEHATIMHWQRNDGEVRPGELLLLDAGVETNSLYTAD
                     VTRTLPISGTFTPLQRKIYDAVYEAQEAGIRTVKPGAAYRDFHVAAQRYLAEKLVEWGL
                     LEGDPDDVYELALQRRFTMAGTGHMLGLDVHDCAKSRTELYVDGILEPGMILTVEPGLY
                     FQPDDLTVPAEYRGIGVRIEDDILVTADGHENLSAGLPRTSDEVEEWMRVLTGA"
     gene            complement(9583..10023)
                     /locus_tag="LUX31_RS09225"
                     /old_locus_tag="LUX31_09225"
     CDS             complement(9583..10023)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040373.3"
                     /locus_tag="LUX31_RS09225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09225"
                     /product="DUF6299 family protein"
                     /protein_id="WP_235474298.1"
                     /transl_table=11
                     /translation="MSVSFRSLSRAAAVAAGAALLTVSQAATPAAADEGFDQVTVESGS
                     ITPDGELTLAGSYRCLSTGGSVRVAASIERGENVWHGLDSIPASCDGSWHQWSNTKATE
                     PGAYEPGPVRVKTSLVEFRRSGFIPLPTVHSERIQEVVLTQA"
     misc_feature    complement(10151..10165)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.99"
                     /tool="antismash"
     misc_feature    10153..10170
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.77"
                     /tool="antismash"
     gene            10328..10516
                     /locus_tag="LUX31_RS09230"
                     /old_locus_tag="LUX31_09230"
     CDS             10328..10516
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006375664.1"
                     /locus_tag="LUX31_RS09230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09230"
                     /product="DUF5999 family protein"
                     /protein_id="WP_105968663.1"
                     /transl_table=11
                     /translation="MCSHQPACPSADRPDRDAAHIVAFHPEQGWNLLCNGAIVFDDTGE
                     LLPDGSVVSPHRLTTAA"
     gene            complement(10535..10933)
                     /locus_tag="LUX31_RS09235"
                     /old_locus_tag="LUX31_09235"
     CDS             complement(10535..10933)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019523541.1"
                     /locus_tag="LUX31_RS09235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09235"
                     /product="RidA family protein"
                     /protein_id="WP_235474299.1"
                     /transl_table=11
                     /translation="MSAERVNPAGLSPPAGFSHAVVATGSRLVFLAGQTALDADGKVVG
                     DTLVEQFERALGNLLAALHAAGGTPADLARVTVYATDVADYRAQAPQLGRVWRRLAGRD
                     YPAMAVVGIVRLWDEEALVELDGFAVLP"
     gene            complement(10930..12069)
                     /locus_tag="LUX31_RS09240"
                     /old_locus_tag="LUX31_09240"
     CDS             complement(10930..12069)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657214.1"
                     /locus_tag="LUX31_RS09240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LUX31_09240"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_235474300.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.6e-10, bitscore:
                     38.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.4e-21, bitscore:
                     73.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.6e-46, bitscore:
                     155.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAFSLEPAQAAWCAELRALAADRLRPLAEKGEPGRVNRPLVAEL
                     GQLGLLSRLFTSGALDLCLMRESLAHACTEAETALALQGLGAHPVHAHGAPAQRARWLP
                     RVSEGSAVAAFALSEPGAGSDAAALSLTAAPDGPSGWRLTGEKCWISNAPEADFYTVFA
                     RTTAGAGARGVTAFLLPADRPGLTGSALDMLSPHPIGALALDAVPVTVDDVIGEPDRGF
                     RVAMGTLNLFRPSVGAFAVGMAQAALDATLAHTAQRDAFGGKLKDLQAVSHQIAEMALR
                     TEAARLMVYAAAAAYDEGAQGVPGRAAMAKLLATETAQYVVDAAVQLHGARALRRGHLL
                     EHLYREVRAPRIYEGASEVQRTVIAKELYKESQGTGEAL"
     misc_feature    complement(12884..12895)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: strong, score: 20.58"
                     /tool="antismash"
     misc_feature    complement(12920..12933)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.79"
                     /tool="antismash"
ORIGIN
        1 tcagggcctg ttccgcccag atcgtcttgc cgttcctggt gtgccgggtg ccccagctgg
       61 tggtgagctg ggcgacgagg aggaggcccc ggccgccctc gtcggagatc ctggcccggc
      121 gcagatgcgg tgaggtggaa ctgccgtcgg agacctcgca gatgagcgta cggtcgtgga
      181 tcagccggag ctggatcggg tcggcgccgt agcggatcgc gttggtgacc agttcgctga
      241 cgaccagttc ggtgacgaac gcggcctcgt cgagccccca ttccgtcagc tgtgcgacgg
      301 cgcgtctgcg ggcctcggcg accacctcga agtcggcggg caggtcccag acacggacgt
      361 ggtcggcgtc cagggcgcgg gtgcgggcca gcacgagggc gacgtcgtcg ctcgggtggg
      421 tcggcagcag ggcggacagg acctggtcgc agcggtcctc cagcgggcgg gtgtcgtcgc
      481 cgtcggccag ggtccgggcg agcagggcga tcccgaggtc ggcgtcacgc tcggtggcct
      541 ccaccaggcc gtccgtgaac agggcgacga gggtgccttc cggcaggagg ctctcggtgg
      601 tctcgaaggg caggccgccg acgccgagca ccggcccgac ggcgacgtcc acgacccggg
      661 tgtccccgtc cggcaggacc agcacgggtg gcggatggcc ggcactggca acggccaact
      721 cgcgggagac cgggtcgtag acggcgtaca gacaggtcgc cccggtggct ccgacgccga
      781 tccgcgcgtc gctcgcgtca ctgtcgtcgt cggcggcgag gcgcaggacc aggtcgtcga
      841 ggtgggccag gagttcgtcg ggcggcagat cgacgtcggc cagggtctgg accgccgtac
      901 gcagtctgcc catggtcgcc gaagcctgga tgccgtggcc gacgacgtcg ccgacgacca
      961 ggccgacgcg cgcccccgac agcgggatga cgtcgaacca gtcaccgccg acgcccgcgc
     1021 gggagtcggt cggcagatag cgggaggcca cgtccaccgc cgactgccgg gacgggccgc
     1081 gcggcagcag gctctcctgg agggcgaggg cggtggtgcg ctcgcgggtg tagcggcggg
     1141 cgttgtcgac gcagagggcg gcgcggctcg ccagctcctt cgccaggacg aagtcgtcct
     1201 cgttgaagac gtcgtcccgg gtgcgcagca ggacggcgac cccgagcgtc gtaccgcgcg
     1261 cgatgagcgg caccgcgacc agcgaggtga cgacggttcc gcgcaggctc tcggcccgtt
     1321 cgggcgcgct cgccatccag tggtcgaagt cgggggcgcc gctgcggctg agcaccgtct
     1381 gtccggtgcg cagcgcccgc gcgggcgggg agtacggcgg atacgtgtcg gtggcgccca
     1441 gccccatcac cgcgccgggc acccactccg agccggaggc gtgggcgagg cggcgcagga
     1501 cgacctcgcc gtccggcccg gcctcggcgg gctcgtcgcc gcgcatgacc gcctccagca
     1561 ggtcgacgct ggcgaagtcg gcgaaccggg gcacgaccag gtcggcgagt tcctgggcgg
     1621 tccggtcgag atccaggctg gtgccgatcg acacggccgc ctcgtcgagc accgcgagcc
     1681 gctgccgcgc ccagtgctgc tcgctgctgt cgaacgcggc catcccgacc gcgcacacct
     1741 cgcccgaggc gtcccggacg ggccacaact ccaggttcca ggcgtgctcg cggatcccgg
     1801 agggcgcccg cgtgaagctc tcgtagtgcg tgggcttgcc cgtcgcggcc acctcccgca
     1861 gggccgccag catgccgagc tgctcgacgt ccgccggcac gccgtacggg aagacctgac
     1921 cgagcaacac gtcctcgtcg acgcccatca cctggcaggc cacgtcgttg agccgccggt
     1981 accgctgctc gatgtcgaac acggacatcg agtacgacgc ctgctggaac gcctgttccg
     2041 ccaggtcggg tccgacctga tgttcgtcgt ccgcgtgctc ggaggccatg gattcagtgt
     2101 cctcccgccg cccggagggc aacaaccgaa cacgtccgaa cgcgcacggt gagttcgtgt
     2161 acgccattcg cgcaacgggt acggggtgat tcagtgggcc cagtcgcccc ggacatggcc
     2221 cagatgccgg gtcatcgcgg tccgtacacc tgccgcgtcc cgggcgagga gcgcgtcgag
     2281 gatctccagg tgctcctcgg cgctggacgt cagcagcccc cgctcggcca gcgcggtcag
     2341 cccgtacagc cgggaccgtt tgcgcaggtc accgacgacc tcgaccagat gctcgttgcc
     2401 ggccagggcg agcagaccga ggtggaagcg gcggtcgctg tcgacatagg cgatgaggtc
     2461 gccgctctcc gccgcggcca cgctgtccgc cgcgtccttg cgcagcgcct caagggcggc
     2521 cgggtcggcg gtcgcggcga ggccgacggt ggtcgggatc tcgatcagcg accggatgtg
     2581 ggtgtactcg tcgagctgcc gctcggagac cgtggtgacc cggaacccct tgttgggtac
     2641 gggatcgacc atgccctcct tcaccaggtc gagcatggcc tcgcgcaccg gggtggccga
     2701 gacgccgaag cgggcggcga gcgagggcgc cgagtagacc tcgccgggcc gcagttcacc
     2761 ggcgacgagc gcggcccgca gcgcgtcggc gacgctcgcc cgatagctgg gccgcggccc
     2821 gccgaggctg ggcagggcgg ggccggtgcg ctgagcggcc atgggtgtct cctggatggt
     2881 tctcggaact cgctggttgt cgtgtggctg cttgttgatt cgtggcggtg tcagagtacg
     2941 aagccggccg ggaacggatc gtccgggtcc agcagatact gggcggtgcc cgtgacccag
     3001 gcccgcccgg tgatcgtggg caccacggcg ggccgcccgg cgacctcgac actctcgacg
     3061 agccgcccgg tgaacgacgt accgatgaag gactcgttca agaagtcctg gtgcaagggg
     3121 agttcaccgc gcgcgtgcag ctgggccatg cgcgcggagg tgccggtgcc gcagggcgag
     3181 cggtcgaacc agccggggtg gatggccatc gcgtgccggg accgggtcgc gtccgagccg
     3241 ggggcggcca agtagacgtg gtggacaccg ttgatggtcg ggttctcggg atgtacgggg
     3301 ggactgtcgg cgttgatcgc gtccatcagg gcgagtccgg cggcgaggat gtcgtcctta
     3361 cggtcgcgct cgaagggcag gccgaactcg tcgaggggca ggatggcgta gaagttgcca
     3421 ccgaaggcga ggtcgtacgt caccgtgcga ccgtcggcga gggtggcttt gcgccccaac
     3481 tccacggcga aagaaggcac gttgcggatg gtgaccgcct tggccgcacc gccctccacg
     3541 gacacctcgg cgacgacgag cccggccggg gtgtcgagcc ggatggtggt gaccggctcg
     3601 acgaccggga ccatgccggt ctcgacgagc acggtcgcga caccgatcgt cccgtggccg
     3661 cacatcggca gatagccgga gacctcgatg tagacgacgc cgtagtcgca gtcgggccgg
     3721 gtcggcggct ggaggatcgc cccgctcatg gcggcgtgcc cgcgcggctc gttcatcagg
     3781 aagttccgta cgtcgtcccg gtgttcgcgg aaccacagcc ggcgttcgtt catcgtgtcg
     3841 ccggggatgg tgccgatccc gccggtgacg acccgggtcg gcatgccctc ggtgtgcgag
     3901 tcgacggcgt gcaggacgag cttgctgcgc atggggcgat cctctcaggt cggcgggcag
     3961 gcggagttgc ggctcaggcg agaccgaggg cgacggcctt ctcggtggct tcgcggaccg
     4021 ccttctcctg ctcgggcagc agcggcatgc gcggcgggcg gacaggaccg ccatgccggc
     4081 cgacgatgtc catcgacagc ttgatcgcct gcacgaactc gaccttggag tcccagcggt
     4141 ggagtgcgtg cagctgctgg tagagcggca gggcggtggc caggtcgccc gcgacggcgg
     4201 cgcggtacag ctcgaccgtg gcccggggca gcgcgttggg atacccggcg acccaaccga
     4261 ccgctccggc ggtcgccagc tccagcagga cgtcgtcagc gccgatcaac acatcgagtt
     4321 ccggggcgag ttcctggatc tggtagatgc gccgggtgtc tccggagaac tccttcactc
     4381 ccttgatgag cccggccgcg tgcagcttgg ccaacaactc gggggtgagg tcgaccttgg
     4441 tgtcgatggg gttgttgtac gccacgatgt cgatcccgac ctcggcgacg gccgcgtagt
     4501 gcgcgagcac cgaacgctcg tcggcccggt aggcgttggg cggcagcagc atgacggcgg
     4561 cacagccggc gtccttggcc tgcgcggccc agcgagcgga ctcggcggaa ccgtaggcgg
     4621 cgacaccggg catgacccgg tccccgccga tagcggcaac ggcggtctcg acgactttcg
     4681 tccgctcctc ggcggtgagc acctgatact caccgaggga gccattgggc acgacaccgt
     4741 cacacccgtt ctcgacgagc caacggcaat ggtccgcgta ggcggcgtag ttgacgctca
     4801 gatcgtcgtt gagcggcagc gcggtggcaa cgagaacgcc acgccagacg gggacggggg
     4861 cggtggtgcc cataagaacc tccagttttc gagatacaga ggagaagcgc gccccatagg
     4921 ggcgcgggac tgtttctaat ctgcggctcc gccgcgtggg cgcgaccagc cacaacggcc
     4981 ccgcagccaa atcacaacca tcagcaccga ggctcctccg ccaacacccc caacggcaca
     5041 ggtccagcaa acggccgctt ggccaccccc accgaacacc cggcaacccc agcgaccccg
     5101 gtcgcacaga cccgcccctg acaccacccc atacccgcac gagtgagcag cttcacggta
     5161 cgcaaatcag tcgcccccaa ctcctcgacg gcctcccgga cttcggaggc cgtcacctcc
     5221 tcgcaccgac agacgacggt gtcatcggca acctgctcca cccagcgcgc aggcggcgcg
     5281 tacgcggtat caacggcagc gaagaacttc cgcagccggg tacgggtccg cgcggcagcc
     5341 gcccagtcgg caggacgagg ctcaactccc cccagccgcg cggcgatcga gcacccggcg
     5401 atctccccct cggcgagcgc cagcaccgct cccccgatgc cggtggcctc gcccgccgcc
     5461 cagacaccgt cgacgtcggt gcgctgctcg gcgtcggtga cgacgaaggg gtcgccggtg
     5521 gcgtcgatcg cgcacccgag ggtctcggcg aggtcggtgt gcgcgagcat gccgtggccg
     5581 acggccaggg tgtcgcaggc gatccgccgc tcggtgccgg gccgtacccg accgtccggg
     5641 tccagggcgg cgacggtgac ggcttcgacg cggtcggtgc catgggccgc gacgacggtg
     5701 tgacgtaccg tcaccgggac cttgtggcac aggagttggg ccgcgtactg aacggcctcg
     5761 gcgatcttcg ccgggttggc ggcgagtgtc gcggtgtgcc gtacgaagtc ggcggggtgc
     5821 gtggactcga cgtacgcggc gacttcggcg cccgctgcgg cgagcccggc cgcgaccggc
     5881 atcagcagcg gcccggtacc ggcgacgacc gccgtacggc ccggcagaac gagcccgccc
     5941 ttgagcatgg cctgggcgcc accggcggtg accacaccgg ggagagtcca gccagggaag
     6001 ggcaacacct tctcgtagcc accggtggcg aggaggacgg catcggcggt gacggtctcc
     6061 gactcggcct gcgcgggacc gagaagagca tgcacgccaa aacgaccact tccgccgaac
     6121 tccccctcta cgaaccacac atgacgatcc gccaggtggg tgatccgacc cgccgcgaca
     6181 tgcgccgcca gccgatcccg cagcttctcc caggtacccc aggcgtgatg cagggcctgc
     6241 ggccgacgcg ccttcaacgc cgcagcgggc tgccggtaga actgcccacc ggcctgggca
     6301 cccgagtcga gcagcaccac ccgtacgccc aggtcggcgg cggtcagcgc ggcagcgagg
     6361 cccgccggac cggcaccgac aatcgccacg gatgaagtcg ggtgcgcgcc agcgccccga
     6421 taggggcgcg gggaactgcg cgaccagccc ccaccggccc gcagccgacg aaccagataa
     6481 cccaccgaac gctcacccga gttcgtcatg accaacccct tcctgcgtac ggatcacgtc
     6541 gccggacgca gccggtacca ggcaagcccg ctggttaggc cggtcattga cggtgacaag
     6601 gcagtcgaag cagaccccga tcccacagaa gatcccgcgc ggcgcaccac tcccccgggt
     6661 gctccgccag gaggtgaccc ccaccgacca gaggacggcg gcgacagtct gaccgggcag
     6721 cgcagcggtc tcgtgtccgt cgacagtgac ggtgaagggc ggcccggggt gggccctggc
     6781 cagctccagc ggagtcctct gtctcactga ttgccctcct cgaagcggtc cggacggaac
     6841 ggcgcgaggt ccagatcggg ccgcttgccc gccaacgact gcgcgatcaa ctgccccgta
     6901 ccgaccgcca gcccgatccc cgccccctcg tgaccgcacg cgtgatagag ccccggcgcc
     6961 cggggatcgg ccccgatggc cggcagatgg tccggcatgt acggccggaa acccaggtaa
     7021 gcgcgcatcg cgtgcacact cccgagcacc gggaagagcg ccagggcctg cgcggccagt
     7081 cgacgcacga ccgggagcga gaacgtccgg tcgaagccga cccgttcacg gctggccccg
     7141 atcagcaccg gccccgcggc cgtgctctcg acgaccgccg aggactggag ccctgcgtcg
     7201 ccgctggcca cgtcggcgac atagtcggcg gcgtacacct tgtgccgtac ggtgccgggc
     7261 ggcagcggtt cggtgaccag gacgaagccg cgccggggca gcacgggcag gtgcaccccg
     7321 gccagcgcgg cgacctcgcc gccccaggtg ccggccgcgt tgacgacggc cggggcgtgg
     7381 atgtcgccgt gctccgcagt ccggacgccg cgtacggagc cgtccggtgc gcacaggatg
     7441 tcggtgacgg ccgtaccggt gcgcagttcg gctccggccc gccgggccgc ccggacgacc
     7501 tgggcggcgg cgagggaggg catcacctgg cagtcctgcg ggtacagcac accgcccgcg
     7561 aggtcggggg ccaagtgcgg ttccaggtcg gcgagttgac cagcgtcgac cgtctcggcc
     7621 tcgatgcccg ccgcccgctg tccggcggcg aacccggcca gcgcggccat gcctgccgcg
     7681 tcggaggcga cgacgatccc gcccttcgcc tcgaactcga cggcgccgcc cagacccggt
     7741 tcggccgcga ggtcgtgcca gaggcgggcg gagagcagcg cgaggtccag ctcgggcccc
     7801 ggttccttgt cggagacgag caggttgccc tcaccggcgc cggtggtgcc accggccacc
     7861 ggcccccggt cgaggacgag ggtcgcgagg ccggcccggg cgaggtaaag ggcacatgcg
     7921 gcacccacca ttccggcgcc gatgaccaca acatcgcagg tcagtcgctt actcacatca
     7981 gtacaatgtc acatgttcct attctcgcca agggcgccta ggctcgactc accgaccgac
     8041 tgctgctgac ctcaaggcga agaaggtgcc cacaggtgtc cacggattcg accgaaaccg
     8101 ctgaacccga agagaccgct gagaccaagg accgcaagaa ccgcctgtac ccgtccgtct
     8161 ccccgcagct ggccgagctg atgacgacgg gatgggccga caccgagctg aaggacctgc
     8221 gccccatcga gcaggccccg tacgccgccg agcgccgcgc cgccctctcc gcccgcttcc
     8281 ccggcgagcg tctgatcgtc ccggccggca acctcaaggt ccgcgccaac gacacgcact
     8341 acccgttccg cccgtccacc gagtacgtcc atctcacggg cgaccagacg gtggacgcgc
     8401 tcctcgtcct cgaaccccgc gcggacgccg acggtcacga cgccgtcgcc tatctcctcc
     8461 cccgctccga ccgggacagc ggcgagttct ggcagggcgc ggccaagggc gagctgtggg
     8521 tcggccgccg ccactccctc gccgaggccg aacaggtcct cggcctgccc tgccgtgacg
     8581 tccgcgaggc ctccgccgag ctgcgcgcgg cccccgccgt ccccacccgg atcgtgcgcg
     8641 gctacgacgc cgaactcgag gccgccgtga cgacggacga ggaccgggac accgagctga
     8701 agacggtgct gtccgagctg cgtctggtga aggacgactg ggagatcggc gagatgcgca
     8761 aggcggtcga ctcgaccgta cgcggattcg tggatgtcgt acgggagttg gcgaccgcga
     8821 tcgccacctc ggagcgctgg atcgagggaa ccttcttccg ccgcgcccga cttgagggca
     8881 acgacatcgg ctacggctcg atctgcgcgg ccggcgagca cgccacgatc atgcactggc
     8941 agcgcaacga cggcgaagtc cgcccgggcg agctgctgtt gctcgacgcg ggcgtggaga
     9001 cgaactccct ctacaccgcc gacgtcaccc gcaccctccc catcagcggc accttcaccc
     9061 cgctccagcg caagatctac gacgcggtgt acgaggctca ggaggcaggc atccggacgg
     9121 tcaagcccgg tgccgcgtac cgggacttcc atgtcgccgc ccagcgctac ctggccgaga
     9181 agcttgtcga gtggggcctg ttggagggcg acccggacga cgtgtacgag ctggccctcc
     9241 agcgccgctt caccatggcc ggcaccggtc acatgctcgg cctggacgtg cacgactgcg
     9301 ccaagtcacg gaccgagctg tatgtcgacg gcatcctcga accgggcatg atcctcacgg
     9361 tcgagccggg cctgtacttc cagccggacg acctgaccgt gcctgcggag taccggggca
     9421 tcggggtccg gatcgaggac gacatcctgg tgacggcgga cggccacgag aacctgtcgg
     9481 ccgggctgcc ccgtacgtcc gacgaggtcg aggaatggat gcgggtcctg accggcgcgt
     9541 agccccggtc aagccccgtc aacgcccgct gcggcaggcg gctcacgcct gcgtgaggac
     9601 gacctcctgg atccgctccg agtggaccgt cggcagcggg atgaagcccg agcggcggaa
     9661 ctccaccagg ctggtcttga cccgcaccgg gccgggctcg tacgcgcccg gctcggtggc
     9721 cttggtgttc gaccactggt gccaggagcc gtcgcagctc gcggggatgc tgtccaggcc
     9781 gtgccagacg ttctcgccgc gctcgatcga ggcggcgacg cggacggaac cgccggtgct
     9841 gaggcagcgg tagctgccgg cgagcgtgag ttcgccgtcg ggcgtgatgc tgccggactc
     9901 gaccgtgacc tggtcgaagc cctcgtcggc ggctgcgggg gtcgcggcct gggacacggt
     9961 cagcagcgcg gcaccggccg cgacggcggc ggcacgggag agggaccgga aggaaacaga
    10021 catggggaaa cctccttggg gggactccac aggtactggc cccccgcgcc cgcgcgcgtg
    10081 atcatcaccc cttcgtcggc gagtcgtgca cgccgactgc cccgcttttc ggatcttctc
    10141 ggaacggcgg aattgtcaga gtggtgtcac agcacgtccg cgtgctgtca cgcttcctcg
    10201 cctcgacttg gcgccgggcc cccggcacgg gcatcgtcag aaccggcaag gaagcaaggc
    10261 cgcaaagacg caaggactca cggacgcacc gcacccgagc accagctatc cgatccggag
    10321 gcacaccatg tgttcacacc agcccgcgtg cccctcggcc gaccgccccg accgggacgc
    10381 cgcgcacatc gtcgccttcc accccgagca gggctggaac ctcctgtgca acggcgcgat
    10441 cgtcttcgac gacaccggcg agctgctgcc cgacggcagc gtggtctccc cgcaccgcct
    10501 gacgaccgcg gcctgaacaa cctctgacca ctctctacgg cagcaccgcg aagccgtcca
    10561 gctccaccag ggcctcttcg tcccacagcc gtacgatccc gacgaccgcc atcgccggat
    10621 agtcgcgccc cgccaacctc ctccagacac ggccgagttg aggggcctgg gcgcgatagt
    10681 cggcgacgtc cgtggcgtac acggtgaccc tggcgaggtc ggcgggcgta ccgccggccg
    10741 cgtgcagtgc ggcgagcaga ttcccgaggg cccgctcgaa ctgctcgacc agcgtgtccc
    10801 ctacgacctt cccgtcggcg tcgagcgcgg tctgccccgc gaggaacacc agccgggagc
    10861 cggtggcgac gacggcgtgc gagaagccgg cgggcggcga gagcccggcc ggattgacgc
    10921 gctcggcact cacagggcct cccccgtccc ctgggactcc ttgtacaact ccttggcgat
    10981 gaccgtccgt tggacctcgc tcgccccctc gtagatacgc ggcgcccgta cctcccggta
    11041 gaggtgttcg aggagatggc cgcgccgcag cgcccgcgcg ccgtgcagct ggacggccgc
    11101 gtcgacgacg tactgcgcgg tctcggtggc cagcagcttc gccatcgcgg cgcgcccggg
    11161 gaccccttgg gcgccttcgt cgtacgccgc cgctgccgcg tagaccatca gccgggccgc
    11221 ctccgtgcgc agggccatct cggcgatctg gtgggagaca gcctggaggt ccttcaactt
    11281 gccgccgaac gcgtcccgtt gggccgtgtg ggcgagggtc gcgtccagcg ccgcctgggc
    11341 catgccgacc gcgaaggcgc cgacgctcgg ccggaacaga ttgagtgtgc ccatggcgac
    11401 ccggaagccg cggtcgggtt cgccgatgac gtcgtccacg gtcaccggta cggcgtcgag
    11461 ggcgagggct ccgatggggt gcggggagag catgtcgagg gcgctgccgg tgaggccggg
    11521 ccggtcggcg gggagcagga aggccgtgac tccacgggcc ccggcgcccg ctgtcgtacg
    11581 ggcgaagacg gtgtagaagt cggcctcggg ggcgttggag atccagcact tctcgccggt
    11641 gaggcgccag ccggaggggc cgtcgggggc ggccgtgagg gacagggccg ccgcgtcgga
    11701 gcccgcgccg ggctcgctca gcgcgaaggc ggccaccgcg ctgccctcgc tcacccgggg
    11761 cagccagcgg gcccgctggg ccggggcgcc gtgggcgtgg accggatggg cgccgaggcc
    11821 ctggagggcg agggcggtct ccgcctcggt gcaggcgtgc gcgagggact cccgcatcag
    11881 gcacaggtcg agcgctccgg aggtgaacag gcgggagagc agcccgagtt ggccgagttc
    11941 ggcgacgagg ggacggttga cgcggcccgg ttcgcccttc tcggcgagcg ggcgcagccg
    12001 gtcggcggcc agcgcgcgca gctcggcaca ccaggcggcc tgtgccggtt cgagcgagaa
    12061 tgcgggcatc gccggtcctc cctccgaggc cgtcgtccac ggcccctccc cgacggtatc
    12121 gcgcaccgtt gactgccgtc accaacacga tacgctcctt gtgcaggaca ggtctcggcc
    12181 caccactacg cctacgccca cgacggcaaa ggggcgaacc gccatggatc ccatgcaccc
    12241 catgcgtccc aggcatcccg ggtacggcag ggctcccgag ggccgcgccg atcccgcgcg
    12301 gcgggttccc tcggcccacg tggacacgtt cgcgcgcgac agcctcccgc ccccggacca
    12361 gtggcccggc ctccgcttcg acctgcccga ggtgcgttac cccgaccggc tgaactgcgc
    12421 ggccgagctg ctggccggcg acggttccga ccccgggcgc ccggtgttcc gtacggccgc
    12481 cggtgaggtg tggacgtacg gcgagctgcg cacccgggtc gaccgggtcg cgcacgtcct
    12541 cacccgggac ctcggggtcg tgccgggcaa ccgggtcctc ctgcgcggcc ccaccacacc
    12601 ctggctcgcg gcctgctggc tggcggtgct gaaggcgggg gcggtcgcgg tcaccgtgct
    12661 ggcccagcag cgtccgcagg agctgagcac gatgtgcgag atggcccgga tagggcacgc
    12721 cctgtgcgac atccgggccc tcgacgacct cgccaaggcg gagataccgg ggctgcggat
    12781 cgtgccgtac ggcggtgacg gcctcgacga cctgctgaac cgtccggtgc ccggcacccc
    12841 gtacccggcc gtggacaccg cggccgacga cgtggcgctg atcgcgttca cgtccggtac
    12901 caccggtcgc ccgaaagggt gcatgcactt ccaccgggat gtgctcgcca tcgccgacac
    12961 gttctcgcgg cacgta
//
