LOCUS       NZ_CP054019            22757 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. A1-5 chromosome.
ACCESSION   NZ_CP054019
VERSION     NZ_CP054019.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. A1-5
  ORGANISM  Streptomyces sp. A1-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9459690)
  AUTHORS   Dashti,Y., Sumang,F.A.M., de los Santos,E.L.C., Alcantara,E.P. and
            Challis,G.L.
  TITLE     Structural revision and biosynthesis of polyketides FXJ15321 and
            FXJ15322 from Streptomyces sp. A1-5
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9459690)
  AUTHORS   de los Santos,E.L.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2020) Warwick Integrative Synthetic Biology
            Centre, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL,
            United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUN-2019
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:28:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,328
            CDSs (total)                      :: 8,230
            Genes (coding)                    :: 7,847
            CDSs (with protein)               :: 7,847
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 383
            CDSs (without protein)            :: 383
            Pseudo Genes (ambiguous residues) :: 0 of 383
            Pseudo Genes (frameshifted)       :: 156 of 383
            Pseudo Genes (incomplete)         :: 280 of 383
            Pseudo Genes (internal stop)      :: 26 of 383
            Pseudo Genes (multiple problems)  :: 73 of 383
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:08:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9428877
            Orig. end                         :: 9451634
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Philippine National
            Collection of Microorganisms.
FEATURES             Location/Qualifiers
     region          1..22757
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="42"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22757
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22757
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12757](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12757)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            1093..1584
                     /locus_tag="HRD51_RS41535"
                     /old_locus_tag="HRD51_40995"
     CDS             1093..1584
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS41535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_40995"
                     /product="hypothetical protein"
                     /protein_id="WP_235095842.1"
                     /transl_table=11
                     /translation="MALSASWRGEDITLADVVRLIGLQDTAAEDLQVMVQFQTDSPLGN
                     QAPMSSHLHTVVVNHQVRGMEVARTRLPISRMGTVQRFVADRGSDAVEVRGEQPPGLVE
                     LLGEWHQQQLFEVEFALLVNKDTDLRNWLAVREDTPLGVFGMFYLAVDDFDAYAERSAR
                     "
     gene            complement(2507..2959)
                     /locus_tag="HRD51_RS41540"
                     /old_locus_tag="HRD51_41000"
     CDS             complement(2507..2959)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015649.4"
                     /locus_tag="HRD51_RS41540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41000"
                     /product="bacterial transcriptional activator
                     domain-containing protein"
                     /protein_id="WP_235095843.1"
                     /transl_table=11
                     /translation="MVGLARLHVDVQEFLATARHALGVAERSAEHAFAALTAAEGLYRG
                     DVLADDPYAQWATALREEAQATHAELLARLAAAAAENRDTYAEIHYRLRLLERDPYDED
                     THLALVCLLAAAGRHGEARRRYRLYAGYMNEIDVTPAPYPLRTVKD"
     misc_feature    3724..3737
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.39"
                     /tool="antismash"
     gene            3749..4510
                     /locus_tag="HRD51_RS41545"
                     /old_locus_tag="HRD51_41005"
     CDS             3749..4510
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS41545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_41005"
                     /product="hypothetical protein"
                     /protein_id="WP_235095844.1"
                     /transl_table=11
                     /translation="MLGEDRCLLVRRPGRPQLTTLPVDIADTEQRLCSQRQAHAVPQLV
                     IPRERTGELGCGPVEFTECQQRGGPAAPPRQHHRDREGCVPASRTQCAVQFGKHLSGLS
                     PLDPLLRRAHHRQQPQQGIAHRTGGVLRALPVVLGGRTTAIRGRHGRGRGAGHHAGVRI
                     VAAVQRGHGAPGEGPGLPQRPPGAVGGCGPGRRRDLRGRVQLAGGQVPVGGDCPFRFAQ
                     QLVDRDQPAVRAGPVAQQVCDRRTSCFLAIG"
     gene            4750..5397
                     /locus_tag="HRD51_RS41550"
                     /old_locus_tag="HRD51_41010"
     CDS             4750..5397
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS41550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_41010"
                     /product="hypothetical protein"
                     /protein_id="WP_235095845.1"
                     /transl_table=11
                     /translation="MAVENARGMRVLAVCGGLGLLYAVALGVWLTPSRMLPWALGAVVP
                     CYLAGLSLCWKAPGHPVARRVLAAGAWAALGLVVRFTVALLGPLADWVPGPTTSWPLLL
                     LVRTIDVVAAVMIGRLLALLPDGGERYAHERVALRSLWLLVAAPLVLMAVPMPPVVAAA
                     LAGPARGMDARGGGGPVAGAVDAGRTTPGRPERAGGERSRQWPSPCSPHEAP"
     gene            5463..6797
                     /locus_tag="HRD51_RS41555"
                     /old_locus_tag="HRD51_41015"
     CDS             5463..6797
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="HRD51_RS41555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41015"
                     /product="GAF domain-containing sensor histidine kinase"
                     /protein_id="WP_235095846.1"
                     /transl_table=11
                     /translation="MPYVLISLGLVYVGFRHRLPGLDFTARRSTVYGLLWIIIGGWYLG
                     MVTALGLTASQYLPISTAVLVTVSATMLCQPLRRQANRLAARRVFGARPSNFELLVQFG
                     TTLEHAYDLTLLAPQLAVSLQEWLDLRWVYVELGTLGPERLPFATGTAGVVPDGADSSR
                     TRVGLCYGDDALGFIEYGPKDEGRFTPEDRDLVETLARQAALAVHNARLNAELSIRIEE
                     VQRQASELNASRTRIVQAQDTERRRIERQLHDGIQQELVALVAKLRLARNQLCRNGDTV
                     YTTLTELQDDAYRVIDGLRELAHGIHPPVLTDQGLAAAVMSRARRLPIPVTVEIEPSVR
                     PARFTPDIEEAAFFLVSEALTNVLKHARAGRVMVRIGRAGGSLLLDVSDDGIGLHSTTG
                     PGSGLTGMRDRIEAVGGELSIISRPGDGTTLRARITETRREPTDA"
     gene            6790..7485
                     /locus_tag="HRD51_RS41560"
                     /old_locus_tag="HRD51_41020"
     CDS             6790..7485
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003953022.1"
                     /locus_tag="HRD51_RS41560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41020"
                     /product="response regulator transcription factor"
                     /protein_id="WP_235091809.1"
                     /transl_table=11
                     /translation="MPEPMSDRMRVLIAEDHYLVREGTRRLLEDTGEVVVVAAVGTADE
                     LLDAVHRFRPDAVIADIRMPPDHHTEGITAAHAIRAAHPGIGVVVLSQHANEQYAFALF
                     QHGTDGLAYLLKERIGELEELLRALREVAVGRSVIDPRIVEVLVGSLTRTTDAPLSHLT
                     RRELDVLRHMAQGKNNRSIAESLSLSESTIEKHVNSTFAKLGLAEETQLHRRVTAVLTY
                     LRYGPEPAP"
     gene            complement(7448..9778)
                     /locus_tag="HRD51_RS41565"
                     /old_locus_tag="HRD51_41025"
     CDS             complement(7448..9778)
                     /GO_function="GO:0004181 - metallocarboxypeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012471.4"
                     /locus_tag="HRD51_RS41565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41025"
                     /product="M14 family zinc carboxypeptidase"
                     /protein_id="WP_235095847.1"
                     /transl_table=11
                     /translation="MRALRGRGGALRTVLAVVPVGVVVLAGLPAPALAPAATATAMARV
                     GPSPIDRTVLSADQATPRPCYSAVLRPGTPGVSVREVTSPADGVLRARLTPRGGVSGDW
                     DLAVFDKASGTLVDASSGPHSRELAEGTVTRGQRLVVQGCRYAGRARTVSLGVDVVPGQ
                     GPTAPARPAAARTTARSALPSGRTTYRQLYEYQYELKELARIHPSLVTSFTLPYPTAEG
                     REVSGVEVAADAPRTADGKPVMLALGLHHASEWPSGEIAMEWAYELVSGYRTDARIRAL
                     VRGTRSVIVPVVNPDGFAVSRAAAPKGDFSRFDYEDKRKNCEAGDSPLEYRTGPCLANP
                     AGRMRGVDLNRNYAGFWGGAGSSPVWDDDHYRGSAPFSEPETRNVRSLVSTRQVTDLVS
                     LHTYGDLVVRPPGSNDTQPPLDEPAYRALGDRLASHNGYRSEPARELYEATGMTEDWSY
                     WATGGLGLTLEIGPRTAHPPYAEGVVAEYTGTAPAAGAGKGGNRAALLEMLADTADPAA
                     HATVTGAAPRGYRLRLHKTFRTPTSPVRRPDGSQGPPLEVAETLDSTLLAGGGGFTWSV
                     NPSTRPYVAGRYGREPQAPVQPAVLLSHPPALPPVNTDYPTNPAADRVSFTVEGPPRAD
                     NGRMTVSVNWRSRKTEWDLYVLDPAGRTVGESVVGDTDSQQVVMFDPPPGRYTAVVVDF
                     QQADPAAPDAWTGRVDFRSPLPTVHGPTEAYTLTCEDPGGHRLGSTEVTVGRGQRVEVG
                     EVCGAAAGRRAVRVPVRGRTASR"
     gene            complement(9880..9981)
                     /locus_tag="HRD51_RS41570"
     CDS             complement(9880..9981)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038157.1"
                     /locus_tag="HRD51_RS41570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ALQxL family class IV lanthipeptide"
                     /protein_id="WP_205367436.1"
                     /transl_table=11
                     /translation="MEFDVNALQVLEQEEPESGAWPEPTKCSCCSTF"
     gene            complement(10001..12757)
                     /gene="lanL"
                     /locus_tag="HRD51_RS41575"
                     /old_locus_tag="HRD51_41030"
     CDS             complement(10001..12757)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="HRD51_RS41575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41030"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_235091807.1"
                     /sec_met_domain="Pkinase (E-value: 3.4e-18, bitscore: 64.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-42, bitscore:
                     144.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRDTVLLDVLTAVLSRAGDGEAGPLGGWRVRAGEFWCYVSPPRE
                     TRQVQGWKLHVSATPLSAPVVLSRAAEVLVRRGCRFKFAGTLERAGELVSRHYERGGGG
                     KFLTVYPEGDEDWLRDLAGELHRATLGLPGPGILSDLPCFPHSLVHYRYGVFSGVTTLD
                     GDGMRAAMLIAPDGALVRDNRRPWFAPPSWAPRDPFAPGRVAEPPKPAPVLLHGRFLVR
                     GVIRHAFAGGVYRAVDQDTGHAVIVKQARRHAAATLAGGDARDMRHHEARMLEGFADSG
                     FTPRPVAVFEQQGDLFLVQEAITGVTLRRWVLDRLVLDDGEEWGPDPDEALATARRLAE
                     AMRAVHHRGWVLRDFNPNNVMVTDDGTLRLIDLETLARPGEHVVRVHTPGYAAAEQVHA
                     GRIDAAPGIESDLYSLGATLFYLATGVDPLLAPGDGGGAHKERLVSWLARLSAGNPAAR
                     RLAPLIGALLDDDPTARPALDEVLHRLRTVDGERARSRPAPVSRGIGEGELKQLITDGL
                     DHLLATMDPGRFDRLWPSGPVGTVSDPFNIQHGAAGVLGVLVLAHRLEPQPALRTAVRS
                     AADWISGLVGREPRCLPGLYYGRSGTAWALLDAAGLLADASLLAHATGLAAGTPVEGPV
                     PDVCHGVAGAGLTQLRFWEATGEPRFLDRARRAAEAVAALAVRRDGLLLWPIPGETLAT
                     SDTLAHYGFAHGVAGVGAFLLAAARATGTAAYAELAVEAARTLLAVVEVEGRCAYWRTG
                     EPGSPRKTHWCSGSSGAGTFLLHAWLETGDEDFLTAARQAAAAVRRTRWHEGPTQCHGL
                     AGDGEFLLDLAQATGDGTYRDWAAELATGIHARHVVRDGRMVVPDDTGTAVWADFNTGL
                     SGVVAFLARLAHGGPRMWVPHSLTAAEPEDPGAGVARAASVPVDDLR"
     gene            13577..13747
                     /locus_tag="HRD51_RS41580"
     CDS             13577..13747
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS41580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_235095848.1"
                     /transl_table=11
                     /translation="MPLSVSRRATSSIQGTVSGSPPLSDTTPGRSAAIASVMRSIRSRS
                     ACRVGRRPDSE"
     gene            complement(14506..>15014)
                     /locus_tag="HRD51_RS41585"
                     /pseudo=""
     CDS             complement(14506..>15014)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971303.1"
                     /locus_tag="HRD51_RS41585"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="phosphotransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ADAAAYAAAIDMIRRPAPPYEGRACTGTSNPATRCSTCRPQGRQM
                     PGSPASSTGPRPPRTRPISTWRTAPPISRCRT"
     gene            complement(15336..15530)
                     /locus_tag="HRD51_RS41590"
                     /old_locus_tag="HRD51_41045"
     CDS             complement(15336..15530)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008734335.1"
                     /locus_tag="HRD51_RS41590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41045"
                     /product="transposase"
                     /protein_id="WP_205371438.1"
                     /transl_table=11
                     /translation="MTTEDATEAGSIEMPESQPSKTVDDQLIDELVGRAQAKGLQLTGE
                     GGLLQQPTKQLPLRRQTMR"
     misc_feature    15483..15497
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.64"
                     /tool="antismash"
     misc_feature    15683..15697
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.33"
                     /tool="antismash"
     misc_feature    15719..15728
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 16.35"
                     /tool="antismash"
     gene            15746..16075
                     /locus_tag="HRD51_RS41595"
                     /old_locus_tag="HRD51_41050"
     CDS             15746..16075
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091174.1"
                     /locus_tag="HRD51_RS41595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41050"
                     /product="hypothetical protein"
                     /protein_id="WP_235091805.1"
                     /transl_table=11
                     /translation="MSKGESLVDAAAISRLAKSFDAHGADLESYTKEFRAKTDAEVIDK
                     GFGILTESEEVTSAYIEMSTDMVESLNTLRQHLDHISQGLRTVQQNATASDESLAAGFD
                     QGRHA"
     misc_feature    15764..15766
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15791..15793
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16072..17133
                     /locus_tag="HRD51_RS41600"
                     /old_locus_tag="HRD51_41055"
     CDS             16072..17133
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013021.4"
                     /locus_tag="HRD51_RS41600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41055"
                     /product="WXG100 family type VII secretion target"
                     /protein_id="WP_235095849.1"
                     /transl_table=11
                     /translation="MSGDESVAEEVYEAGLDIINPGGDPDALRTAAKGWRDLHENLQTM
                     FRDLDHEVQRTLESGWHGPAADAFVEHWRHLDAAMQKSLPQLPQAAKSLDEAADAIEEI
                     NHEIHEIYLEIGISIGISVGMSFVTMGFSAAAGAARAAQLAARAAKLAKTLGTILRKVG
                     EAFKTVSRLAKEHRFLKNVLVNWASNTGSTVMANGLTGQDTNLGEAVWQGGLSAVAGTG
                     PGLGVAGKLGGMKGAIRGGAVGNIVGGMAVDGAKTALGTDVSGNEFAADIIINGITGGA
                     GGAAVHGANTHLPPGREGPHFSVDGIINGGVYGAGGVAGQPLKDAMTGAKEESEKNVAP
                     GDPGKKSVRDVFG"
     gene            17130..18473
                     /locus_tag="HRD51_RS41605"
                     /old_locus_tag="HRD51_41060"
     CDS             17130..18473
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS41605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_41060"
                     /product="hypothetical protein"
                     /protein_id="WP_235095850.1"
                     /transl_table=11
                     /translation="MRERDRAAASAGAVAWAGVAAFVVCLLVRKVAPYPRWDLLACLAV
                     SGAATVAWWRMAQRPAGASLKRRAEHTRWWPGRRGGMVALALTVLVMPLLLLMTSAAAT
                     TPELAAIVRGGPVLSRVTVQEIHSTSRNQSRNFTEYTSTVSVALPDGPRGTHLTTESIT
                     TGHPLNKGDRVWALHSSAGAAPGAILSPSRDELHALLSGRISGYEAVLLAMWGCFTAVL
                     AALDLREGTSLRHLNADLIAGRSHMLRVRIAGPAAGFHFPYPGRTGKPTRRRQLSPALR
                     LTLSDGRSRDLFLDRCLDPVPLAEELYGLHGWLYWTPRPNGQSGWTEPALFVLDDSRYL
                     LGATPDGPPPDAHAGAPHGHPVTQPLPSPIPTRAVGPYILWQPHLHKPGVIAFVIAFLS
                     VCLITAGIGYGNPPALGACLATTALGPVIGLLLIGHQRTRYLHSLRST"
     gene            18806..19054
                     /locus_tag="HRD51_RS41610"
                     /old_locus_tag="HRD51_41065"
     CDS             18806..19054
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015449529.1"
                     /locus_tag="HRD51_RS41610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41065"
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="WP_235095851.1"
                     /transl_table=11
                     /translation="MSKPVTIRVDDQLHALLKERAEAEGTTVTALIARAAHDAVRDPRL
                     EGAAEVFRSFVNDHADAFDAAFPEDAPSRLDAPGRAA"
     gene            19056..19427
                     /locus_tag="HRD51_RS41615"
                     /old_locus_tag="HRD51_41070"
     CDS             19056..19427
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979092.1"
                     /locus_tag="HRD51_RS41615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41070"
                     /product="toxin Doc"
                     /protein_id="WP_235095852.1"
                     /transl_table=11
                     /translation="MELYVDIRWLLKRQAEVLPKHPHIHDFTSLVAAVGRHRVNIPRVG
                     ATVDNSWRAATLMHTVIRLRPLPARNALFGAGLVVAYMGAAGEGIDAPYSALIDLARDI
                     DAGRCDTYDAADRIRSWRI"
     gene            19578..19703
                     /locus_tag="HRD51_RS42020"
     CDS             19578..19703
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS42020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_268826809.1"
                     /transl_table=11
                     /translation="MRVPDIRIGETYQVKVPQRIPPALRRVPHSPTRAADDLEGR"
     gene            complement(19816..20064)
                     /locus_tag="HRD51_RS41620"
                     /old_locus_tag="HRD51_41075"
     CDS             complement(19816..20064)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS41620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_41075"
                     /product="hypothetical protein"
                     /protein_id="WP_235095853.1"
                     /transl_table=11
                     /translation="MWVLLHRSERSRSLSTWSYPSEQDALHAAAHMAMGWLDDDPLAQD
                     LFADQAHAQVLARFLELHPDTDLFEVAELVPMRADQF"
     gene            20350..20757
                     /locus_tag="HRD51_RS41625"
                     /old_locus_tag="HRD51_41080"
     CDS             20350..20757
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS41625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_41080"
                     /product="hypothetical protein"
                     /protein_id="WP_235095854.1"
                     /transl_table=11
                     /translation="MAAVREDPGVRDLLLAGWQREQPAARVLEPGLPAGITPPHRGILL
                     GTAASTPSASTNSSDIENTCSSMTSSTLDAITCRAESTAAPLSTPANTSTARTTSRSCC
                     LPQLPTARPSLPDAASVRTGAMIPATSSERG"
     gene            complement(20740..20946)
                     /locus_tag="HRD51_RS41630"
                     /old_locus_tag="HRD51_41085"
     CDS             complement(20740..20946)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS41630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_41085"
                     /product="hypothetical protein"
                     /protein_id="WP_235091801.1"
                     /transl_table=11
                     /translation="MPTLLVDVVERIVVPITALPGPDAGEPCEDTFALEALGRVGALTQ
                     LGPAVSPGTGSISSGWGSSAALR"
     gene            complement(21581..22540)
                     /locus_tag="HRD51_RS41635"
                     /old_locus_tag="HRD51_41090"
     CDS             complement(21581..22540)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520664.1"
                     /locus_tag="HRD51_RS41635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_41090"
                     /product="DUF5937 family protein"
                     /protein_id="WP_235095855.1"
                     /transl_table=11
                     /translation="MIRYRLGAGAASVRWAMSPIHEVVSLAQLLTEPQRHPIFHPWLRR
                     RRRLSLPDLGALTVFMADGAYRPDFLDPSPMSSEPTFEEGMDALLAAPADQTYAELVDA
                     TKGRGAELGRRLLDDPDRARSEAADALHRLWKAVVEPEWPSMRQALRAEMLDRAIQVNR
                     EGLRAVLPRLHPSAACEGDSVTVEKTVDIDVDCPEGLILVPSLFITDRMQCTTSDHWTP
                     TIYYPASGRYLWAAPPTPRSLDRLLGVTRSRILAALTTPLQTTVVARLVNVTPPTASEH
                     LAILRDAGLIDSSRAGRTATHELTTAGRALMAAASPRP"
ORIGIN
        1 gcggtgacgt aggcatccag ccgctcttcc acggctcgtg tcgtcagctc tgtcctcccc
       61 gcctctcgcc atggctgcgt cacctgctgc acttcttctg agcacgccaa cccgtcccgc
      121 acctgccagt acagtcgctc gctcgcggcc tcggcgagca tcccgccggc ctcctcatat
      181 gcctcggcga accgcagacc ccacgccggg ccgtgcagca gcgcgagatt ggtggagcag
      241 tgcgccacat cgagatcaga ggggccccag gaggtcgcgg cccagtcgac gacgccggtg
      301 atccgggcac ccgtcggcct tgcgggcggc acgtcgaaca gcacgttgcc gggttggaag
      361 tcccggtgca ggaaccgccc ttcatagggt ggcgcggggt tgcggatcac gtcgatcgcg
      421 gcggcccatg ccgcctcgtc ggcgcccttg ggaaccacga cggtgtcggc ggtcgtcaac
      481 gccacatact cccggggccg ttcggcgggg cgcatcgcgt ggatcgccac gagttgacgg
      541 gccagcagcg gaatgcgcgt ctccactgcc tcgtcgtcga ggaccgtccg gcccaccaga
      601 tgtgtcatca ggagcgatgg atgctcgcac tgcgcggcgg tcggatcaac cgcgaccagt
      661 tcaggagccg gcacgccggt ccccgccagc agcggcaggg cgccggcctc cctgttcagc
      721 cagtccgcgg cgtgctccac gtagaacggg tcgacgaagc tccgcagcac caggtcacgg
      781 gtgcgtccgt cccgcgtgcc gatggtcagc cgccgcattt cggcagtgat gcccccgcgc
      841 agcgcctcgg tcctgacgat ccgttcgccg gccttgaggt gccgactcac ccaagccagg
      901 gtcaacggtc ggacagtcgc cgcctcatcg tggtcggtca ccgtgccacc tcatcatccg
      961 gacggcctct gggctctcct tgccagcacc ggaggccgga gtgttcgacg cctacggttc
     1021 ttcaccgtac gcgggctgga cgacctgtcg ctgtccctcg cggccagagc ctggtacgcc
     1081 aaggatcagg gattggccct gagcgcgtcc tggcgcggcg aggacatcac gctcgccgac
     1141 gtcgtccgcc tcatcggcct ccaggacaca gcggccgagg acctccaggt aatggttcag
     1201 ttccagacgg acagccccct tggcaatcag gcgcccatgt cgagccacct ccacactgtg
     1261 gtcgtaaacc accaggtgag aggcatggag gtggctcgga cccgcttgcc gatcagccgg
     1321 atggggacgg tgcagcggtt cgttgcggac cggggttcgg acgcggttga ggtgcggggt
     1381 gaacagccgc ccggtctcgt cgagctcctc ggggagtggc atcaacagca gttgttcgag
     1441 gtcgagttcg ctctcctggt caacaaggac accgacctgc ggaactggct ggcggtgcgg
     1501 gaagacaccc cgttgggggt gttcggtatg ttctacctgg ctgtcgatga cttcgacgcc
     1561 tacgcggaaa ggtccgcccg ctgatgaagg tcgccaagga cgccttcgag tcccacggac
     1621 aaagctcttc cacttcaccg acccccaggg ttcgtcatcg gtgtcaccca gcgccagacc
     1681 tggtaaacag ccaccccagc cgcgcgggcg gagccgcacc ccagcggccg cgccctggct
     1741 ggagcagcac cccggcatac gcctggcacg cttcgccgac gtagccgagg acgccgagtt
     1801 gcggatcaac gccactgccg gccacaccac actccaggcc gtgcaagccg cgggtgaggg
     1861 caaccttgcc ggcaagacgc tgatcgacgc cgtcgtcccc gacagcttca ccctccccgt
     1921 cgggcgacgc cggcacctca ccgcggatgc cccgccggct tgggccacgg ttgctcgctt
     1981 cgctgtcgtc ctgccggccg gactctgctg ctccgccgtc gtcgggcgtc gtcgggcccc
     2041 gtgcgccggc ccgcccgtgg atccctgtgg gtccgctgcc gtccgtctaa cggccacgga
     2101 cccggtcgcg ccccagggcc ccgccggcgt ccggcggcct gtcgtcgccg cgacgctcgg
     2161 cgccgccgtg tcgccgagtc cgccgcctgc cgtcggccgt ggccgcgtcg cctggccgct
     2221 gtgcggccgc ggaccgttgt cgtccgggct tggcgagccc ggcttcaggt cctggacgtg
     2281 cacgccgaac accggctgct ggccgaggag atggccggtg cgtggcgggc cgccccggtt
     2341 cctttgactg cgccggccgt tgcgctgccc cgaaccggct gtcgccgacc caccgccggg
     2401 ttccggttcc ggggcgttgc ccggccagag agtgctgccc tttcatctgg tgtccctgcc
     2461 tgactctgac attgatcttg ccgtggtggt atggacccat gcctgatcag tccttgactg
     2521 tccggagggg atagggcgct ggggtgacgt cgatttcgtt catgtacccg gcgtacagcc
     2581 ggtagcggcg ccgcgcttcg ccatggcggc cggccgctgc cagcaggcag accagggcga
     2641 ggtgggtgtc ctcgtcgtac ggatcgcgtt ccagcagtcg aagcctgtag tggatctccg
     2701 cgtaggtgtc acggttctcg gcagccgccg cagcgagcct ggcgagcagt tccgcatggg
     2761 tcgcctgggc ctcctcccgc agagccgtgg cccactgcgc ataagggtcg tccgccaaga
     2821 cgtcgccgcg gtacaggccc tcggcggcgg tcagcgccgc gaaggcgtgc tcggccgacc
     2881 gctcggccac tcccagcgca tggcgtgcgg tggccaggaa ctcctgcacg tccacgtgca
     2941 gccgggccag gcccaccacc tgcttgtccg cgacgatgaa gtggtccctg tgccatgcgg
     3001 cgctgtggat ccagtaccag gcggaggatg gacagtgcca ccgacagccg gtttccgcac
     3061 agggccggat cctgttcggg ccacaaggcc tccatcagca gttcacgcgg tgtgggcagt
     3121 cctcgtctgg ccaccaggag cttgagcagg tcccgtgcct tcttcgactg ccactcctcg
     3181 gcccggaccg agcagccgtc ccggaggacc tggaagccgc ccagcacccg cacgctcgcc
     3241 gatgggcgta ggctcgccgc cgcccggttg agcagccccg cagcctcccc ggccccggcg
     3301 cccaccccga actggcccag ccaggcggtg gcctcacgca cccgcgtcgc gccggcaccc
     3361 tcaagtcgtg cccgtgcgac ggcgaccctg gccacggcca tcggtcgttg cgcagcggac
     3421 cacatcgcct cggcgtcccg caacaaccct tgccgcgtac cagagtcggc ggcacacatg
     3481 gcctccagct ccagcagttc ggcgaagacg gctcggcacc cctgcgcgcc cggctcgttg
     3541 gccgcctgcc aggccgcctc ggcggccgcc tcgcggcgcc cgcccgccag ggcgatccag
     3601 ccgcccgcca gcagggcgcg gattcgcggc ggaccggcgc acccctgccc ggcccgggac
     3661 gccagaactg ccgccgaatg gggttcgctg acccccggga caccgcgagg ccggtcagag
     3721 ccgaggacag agtctgacgg tcgccggatt gctcggtgag gaccgctgcc tcctggtacg
     3781 ccgcccgggc cggccccagc tcaccacgct cccggtggac atcgccgaca ccgagcagcg
     3841 cctgtgctcc cagcgccagg cccacgccgt cccccagctg gtgataccgc gtgagcgcac
     3901 tggtgaactc ggctgcggcc cggtcgagtt caccgagtgc cagcagcgcg gtggcccggc
     3961 ggcaccgccc cgacagcacc acagggaccg cgagggctgc gtccccgcca gccgcaccca
     4021 gtgcgccgtc cagttcggca agcacctctc ggggctctcc ccgctcgatc cgctgctgcg
     4081 ccgtgcccac caccgccagc agccacaaca ggggatcgcc caccgcacgg gcggtgtcct
     4141 gcgcgcattg ccggtggtgc tcggcggccg cacaacggcc atccgcggcc gccacggccg
     4201 aggccgtggt gcgggccacc acgcaggcgt acggatcgtc gcagcggtcc agcgcggcca
     4261 cggtgcgccg ggcgagggcc cgggcctgcc gcagcgcccc ccgggcgcag tgggcggctg
     4321 cggcccaggc cgtcgccgtg atctccgcgg gcgtgtgcaa ctcgccggag gccaggtgcc
     4381 ggtgggcggc gactgcccgt tccggttcgc ccagcagttg gtagaccgcg accagccggc
     4441 cgtccgtgcc ggaccggtcg cgcaacaggt gtgcgaccgc cgtacatcgt gcttcctcgc
     4501 catcgggtaa ctggtgactc ggtgctgccg tctgtgtgat ggtcatcccc gcccctccgt
     4561 gccgtccgtc gcgcggcgct tccacactca ctgcgatccg ggaccaccgg atcgccccgc
     4621 gacgagtgtg ctcggcggcg cgcgggcggc gaatccgggc gccttctgtt cctgtatgga
     4681 ggttctccgc catcccgggg ggaggcatgc gtgctgtaca gggaaaaacg gtcaagcgac
     4741 acttgcccca tggcggttga gaacgcacgg ggcatgcgtg tcctggcggt ctgcggtgga
     4801 ctggggctgc tctacgctgt tgcgctcggg gtctggctca cgccctcgcg gatgctcccc
     4861 tgggctctgg gcgcagtagt gccgtgttat ctggcagggc tgtcattgtg ctggaaggcc
     4921 ccgggacatc cggtcgcgcg gcgggtgctg gcggccgggg cgtgggcggc cctggggctg
     4981 gtggtgcggt tcaccgtagc gctcctgggc cctcttgccg actgggttcc gggaccgacc
     5041 accagttggc cgctgctgtt gctggtccgg acgatcgacg tggtggcggc cgtcatgatc
     5101 ggccggctac tcgccctgct gccggacggc ggcgagcgct acgcccacga acgcgtcgcg
     5161 ctgcggtcgt tgtggctgct ggtcgcggct ccgctcgtgc tgatggcggt gccgatgccc
     5221 cctgtggttg cggctgcgct tgctggtcca gccagaggca tggatgcccg cggtgggggc
     5281 gggcctgttg ctggtgcggt cgatgctgga cgcacgacgc ccgggcgccc agagcgcgct
     5341 ggtggcgaac ggtcgcggca gtggccttcg ccctgttcgc cgcacgaggc tccatgaggt
     5401 tgttccggat gtggcaggga gacagcgggc ctgcatattt cattggctgc gccctgggcg
     5461 cgttgcccta cgttctgatc tcgttgggtc tggtgtatgt ggggttccgg caccggctgc
     5521 cggggctgga cttcaccgcc cggcgctcca ccgtctacgg actgctctgg atcatcatcg
     5581 gcgggtggta cctgggcatg gtcaccgccc tcgggctcac cgcgagccag tacctgccca
     5641 tcagcacggc ggtcctggtg accgtcagcg cgaccatgct gtgtcagccc ctccgccgac
     5701 aggccaaccg gctggccgcg cgacgggtgt tcggggcgcg gccctccaac ttcgaactgc
     5761 tggtgcagtt cggtacgacc cttgagcacg cctacgatct gacgctgctg gcgccgcagc
     5821 tcgccgtcag tctgcaagag tggctggatc tgcgttgggt gtatgtcgag ttgggcaccc
     5881 tcgggccgga gcggctcccc tttgccacag ggacggcggg cgtggtgccc gacggggcgg
     5941 actcgtcacg gaccagggta gggctctgct acggcgacga cgccctcggc ttcatcgagt
     6001 acggacccaa ggacgaggga cggttcaccc ccgaggaccg tgacctcgtc gagaccctcg
     6061 cccgacaggc ggcgctcgcg gtgcacaacg cacggctcaa cgccgaactg tccatccgca
     6121 tcgaggaagt gcagcggcag gccagcgagc tcaacgcctc ccgcacgcgc atcgtgcagg
     6181 cccaggacac cgagaggcgc aggatcgagc gccagctcca cgacggaatc cagcaggaac
     6241 tcgtcgcgct cgtggcgaag ctacggctcg cccgcaacca gctctgccgc aacggcgaca
     6301 cggtgtacac caccctcacc gagctccagg acgacgccta ccgggtcatc gacgggctgc
     6361 gcgagctcgc ccacggcatc catccacccg tgctgaccga ccagggcctc gcggcggccg
     6421 tgatgtcccg ggcccgcagg ctgccgatcc cggtgaccgt cgagatcgag ccgtccgtgc
     6481 gtccggcgcg cttcacgccc gacatcgagg aggcggcgtt cttcttggtg tcggaggcac
     6541 tcaccaacgt cctcaagcac gcccgggcgg gccgcgtgat ggtgcggatc gggcgtgccg
     6601 gcggctcgct gctgctcgac gtcagcgacg acgggatcgg gctgcactcg acgaccgggc
     6661 ccggctcggg actgaccggg atgcgggacc ggatcgaggc cgtcgggggc gaactgtcca
     6721 tcatcagccg gcccggtgac gggaccactt tgcgcgcgcg catcaccgag acacgacggg
     6781 agcccaccga tgcctgaacc gatgtccgac aggatgcgcg tcctcatcgc cgaggaccac
     6841 tacctggtgc gcgagggtac ccgccgtctg ttggaagaca ccggcgaagt ggtcgtggtc
     6901 gcggccgtcg gcacggcgga cgaactgctg gacgcggtgc accggttccg ccccgacgcc
     6961 gtgatcgccg acatccggat gccgcccgac caccacaccg agggcatcac cgccgcacac
     7021 gccatccgcg ccgcgcaccc cggcatcggt gtggtcgtac tgtcgcagca cgccaacgag
     7081 cagtacgcct tcgcgctgtt ccagcacggc accgacgggc tggcctacct cctcaaggaa
     7141 cgcatcggcg agcttgagga actgctgcgg gccctgcggg aggtcgccgt cgggcgttcc
     7201 gtgatcgacc cgcgcatcgt ggaggtcttg gtgggcagcc tcacccgcac cacggacgcg
     7261 ccgctgtccc atctgacacg ccgagagctc gatgtactgc ggcacatggc ccagggcaag
     7321 aacaaccggt ccatcgcgga gtccctgtcc ctgtcggagt cgaccatcga gaagcacgtc
     7381 aactccacct tcgccaagct gggcctcgcc gaggagaccc agctgcaccg ccgcgtcaca
     7441 gcggtgctca cctacttgcg gtacggcccc gaaccggcac cctgaccgcc cgcctgccgg
     7501 ccgccgcccc gcacacctct cccacctcga ctcgctgtcc ccggccgacg gtgacctcgg
     7561 tgctccccaa ccggtgacca cccgggtcct cacaggtcag ggtgtacgcc tcggtggggc
     7621 catggacggt tggcagcggc gaccggaagt cgacacggcc cgtccaggcg tccggggccg
     7681 cggggtcggc ctgctggaag tcgaccacca cggcggtgta ccggccgggc ggcgggtcga
     7741 acatgacgac ctgctgggag tcggtgtcgc ccaccaccga ctcgcccacc gtcctccccg
     7801 ccgggtccag gacgtaaagg tcccattcgg tcttccgcga ccgccagttg accgacacgg
     7861 tcattctgcc gttgtcggcc cgaggcggtc cctcgacggt gaacgagacc cggtccgctg
     7921 ccggattcgt ggggtagtcg gtgttcaccg gtggcagggc gggcgggtgg ctaaggagga
     7981 ccgccggctg gaccggcgcc tgcggctccc ttccgtaccg cccggccacg tagggccggg
     8041 tggaggggtt gaccgaccag gtgaacccac cgcccccggc gagcagcgtc gaatcgagcg
     8101 tctcggccac ctcaagcggc ggcccctgtg aaccgtccgg ccgccggacc ggtgaggtgg
     8161 gggtccggaa cgtcttgtgc agccgcagcc ggtaaccgcg cggcgccgca cccgtcaccg
     8221 tggcgtgcgc cgcagggtcg gcggtgtcgg cgagcatctc cagcagcgcc gcccggttgc
     8281 cgcccttgcc cgccccggcc gccggcgccg taccggtgta ctcggccacc accccctccg
     8341 cgtagggagg atgagccgtc cgcgggccga tctccagggt cagaccaagc cctccggtgg
     8401 cccagtacga ccagtcctcc gtcatcccgg tagcctcgta caactcccga gccggttcac
     8461 tgcggtagcc gttgtgcgag gcgagccggt cacccagggc ccggtacgcc ggctcgtcca
     8521 gcggcggctg ggtgtcgttg gaacccggcg ggcgcaccac gaggtcccca taggtgtgca
     8581 ggctcaccag gtcggtgacc tgacgggtgg agacgaggga ccgcacatta cgggtctcgg
     8641 gctccgagaa gggcgccgag ccgcggtagt gatcgtcgtc ccacacaggt gaggagccgg
     8701 ctccacccca gaagcccgca tagttgcggt tgaggtccac accgcgcatc cggccggccg
     8761 gattggcgag gcacggccct gtgcggtact ccagcggcga gtccccggct tcgcagttct
     8821 tgcgcttgtc ctcgtagtcg aagcgggaga agtcaccctt gggcgccgct gcgcgggaga
     8881 cggcgaagcc gtcgggattg accaccggca caatgacgct tcgggtcccg cgcaccagcg
     8941 cacggatccg ggcatcggtg cggtagccgg agaccagctc gtacgcccac tccatggcga
     9001 tctccccgct gggccactcg gaggcgtgat gcagacccag ggccagcatc accggcttgc
     9061 cgtccgcggt ccggggcgcg tccgcagcca cctccacccc ggacacctcc cgcccctcag
     9121 cggtggggta gggcagggtg aacgaggtga caagggacgg atggatgcgg gccagttcct
     9181 tcaactcgta ctggtactcg tacagttgcc ggtacgtggt acggccggag ggaagcgcgg
     9241 agcgtgccgt cgtccgggcg gcggcagggc gagcgggggc ggtgggtccc tgcccgggca
     9301 cgacatcgac acccagcgac actgtccggg cccgtccggc atagcggcag ccctgcacca
     9361 ccagccgctg cccccgggtg acggtgccct cggccaactc ccggctgtgc ggcccggagg
     9421 aggcgtcgac cagggttccg ctggccttgt cgaacacggc cagatcccag tctccactca
     9481 cgccgccccg tggtgtcagc cgcgcccgca gaacaccgtc cgccggcgag gtgacctcgc
     9541 gcaccgagac gcccggagtc cccgggcgca gcacggccga gtaacagggc cggggcgtcg
     9601 cctggtcggc ggagagcacg gtccggtcga tgggggaggg gcccaccctc gccatggccg
     9661 tcgccgtcgc cgccggcgcc aaggccggtg ccggcagacc ggccaggacg acgaccccca
     9721 ccgggacgac ggccaggacc gtccgcagtg ctccgccacg gccccgcagt gcgcgcatga
     9781 tcttcccttc ccctgcgtcc ggtcggtcgt gtcggttgcc tcggtcggtc accgccctcg
     9841 tcagagcgaa ggcggtgacc tggttgccgg ccgcagccgt cagaaggtgc tgcagcacga
     9901 gcacttcgtc ggctcgggcc aggcgccgct ctcgggctcc tcctgctcca gaacctggag
     9961 ggcgttcacg tcgaactcca ttgccattca cctcctttcg tcatcgcagg tcgtcaaccg
    10021 gtaccgaggc ggctcgcgcc acccccgcac cggggtcctc gggttccgct gccgtcagcg
    10081 agtgcggtac ccacatccgc gggccgccgt gcgcgaggcg tgccaggaag gcgaccactc
    10141 cggaaagccc ggtgttgaag tcggcccaca cggccgtgcc ggtgtcgtcg gggacgacca
    10201 tgcgcccgtc ccgtacgaca tggcgggcat ggatgcccgt cgcgagctcc gcggcccagt
    10261 cccgatacgt gccgtcaccg gtggcctgag cgaggtcgag caggaactcg ccgtccccgg
    10321 ccagaccgtg gcactgggtg ggcccctcgt gccagcgggt acggcgcacg gccgcggccg
    10381 cctgccgggc cgccgtcaga aaatcttcgt cgccggtctc cagccaggcg tgcaacagga
    10441 acgtgcccgc ccccgaggag ccgctgcacc agtgggtctt gcgcgggctg cccggttccc
    10501 cggtccgcca gtacgcgcac ctgccttcca cctcgaccac ggcgagcagc gtccgggcgg
    10561 cctcgacggc gagctcggcg tacgcggccg taccggtggc ccgcgcagcc gccaggagga
    10621 aggcgccgac ccccgccacg ccgtgcgcga acccgtagtg agcgagagtg tcggaggtcg
    10681 ccagcgtctc cccgggaatc ggccacagca gcagaccatc cctgcgcacc gccaacgccg
    10741 ccaccgcctc ggccgcccgc cgcgcccggt ccaggaaccg cggctctcca gtagcctccc
    10801 agaatcgcag ctgggtcagc ccggcccccg ccacaccgtg gcagacatcg ggcaccggac
    10861 cctccaccgg tgtccccgcc gccagccccg tggcgtgcgc cagcagtgac gcgtccgcca
    10921 gcagccctgc cgcgtccagc agcgcccagg cggtacccga ccgcccgtag tacagccccg
    10981 gcagacagcg cggttcgcgc cccaccagcc cgctgatcca gtccgccgcc gagcgcaccg
    11041 ccgtacgcag ggccggctgc ggttcgagcc gatgggccag gaccaggacc ccgagcactc
    11101 cggcggcgcc gtgctggatg ttgaacggat ccgacacggt gccgacgggg ccggagggcc
    11161 acagccggtc aaagcgccct gggtccatgg tggcgagcag atggtcgaga ccgtccgtga
    11221 tgagctgctt gagttcgccc tccccgatac cccgtgacac cggagccgga cgggaccgag
    11281 cccgttcacc gtccaccgtg cgcaaccggt gcagcacctc gtccagggcg ggccgcgccg
    11341 tggggtcatc gtccagcaac gccccgatga gcggagcgag gcgccgcgcg gccgggttgc
    11401 ccgccgacag ccgtgccagc caggagacca gccgctcctt gtgcgcaccg ccgccgtcac
    11461 ccggggcaag cagcgggtcg actccggtgg ccagatagaa cagggtggcg cccaggctgt
    11521 acaagtcgga ctcgatcccc ggtgcggcat cgatgcgccc cgcgtgcacc tgctcggccg
    11581 ccgcgtaccc gggggtgtgc acgcgcacaa cgtgctcccc cggacgggcg agcgtctcca
    11641 ggtcgatcag ccgcagggtg ccgtcgtcgg tgaccatcac gttgttgggg ttgaagtccc
    11701 gcaggaccca gcccctgtgg tgcaccgcac gcatcgcctc ggccagccgg cgagccgtgg
    11761 cgagggcctc gtcggggtcg ggcccccact cctcgccgtc gtcgaggacc agccggtcga
    11821 gcacccaacg gcgcaacgtg acaccggtga tggcctcctg aaccaggaac aggtcaccct
    11881 gctgctcgaa caccgccacc gggcgcgggg tgaagccgct gtcggcgaaa ccctccagca
    11941 tcctcgcctc gtggtgccgc atatcgcgtg cgtcaccccc ggccagtgtg gctgccgcat
    12001 gacgacgcgc ctgcttgacg atgaccgcat gcccggtgtc ctggtccaca gcccggtaga
    12061 caccaccggc gaaggcgtgc cggatcaccc cgcgcacgag gaaccgccca tggagcaaca
    12121 ccggcgcggg cttcggcggt tcggcgaccc gcccgggcgc gaacggatcg cgcggagccc
    12181 acgacggcgg agcgaaccaa ggccgacggt tgtcacggac gagcgccccg tccggggcga
    12241 tcagcatcgc agcacgcatc ccgtcgccgt ccagcgtggt gaccccgctg aagacgccgt
    12301 accgatagtg cacaaggctg tgcgggaagc acggaaggtc ggacaggatg ccaggcccgg
    12361 ggagccccag ggttgcccgg tgcagctcac cggccaggtc tcgcagccag tcctcgtccc
    12421 cttccgggta gacggtgagg aacttcccac cgccgccccg ctcgtagtgc cgcgaaacca
    12481 gttcgcccgc acgctcaaga gtcccggcga acttgaaccg gcagccgcga cgtaccagta
    12541 cctcggcggc gcgcgacagt acgacggggg ccgacagcgg cgtcgccgaa acgtgtagct
    12601 tccagccctg cacctgccgt gtctcgcggg gcggggagac gtaacaccag aactccccgg
    12661 cccgtacccg ccatccgccc agtggacccg cctcaccgtc cccggcgcgg gagagcaccg
    12721 ccgtgaggac atcgagcagc accgtgtcgc ggaccatgtc acctccctcc ccctcaagcc
    12781 gacaggacgg acctgcacat cggggcgacg agcgaaccgg gcgcgatcag catccgtgcc
    12841 gaaccggtgg tccatgagcc gcaccgcctc cgcccagtca gccatggtgc ggaccgccga
    12901 cagcgtgcgg accacgaacg ggtcggccca cctctccaca gcccgccgcc agagcacctc
    12961 caccggttcg tcgaggagat tgccgaccgt cccctcgtac accggcatag cccgtacctc
    13021 gccgtccggc tccacctgga tgacctcaaa gcccagcccc cgcgccacct ggtcgggagc
    13081 catccgcagc tccaggttgt ccgaagtgag caccaaaacg cccggtggtg caagagcggc
    13141 aagacgcgcc cgctcctgct cactgcccag ccggcgcacc tgctcctcgt ccagcagctc
    13201 ccgctcgacg aatccgggcc gactggcgag cccggcaggg atcaccgcct ggaacgacac
    13261 gatccgcaac tcggggaaac gcggggcgat ccgggcacag aacgtgtcca ggtgatcggc
    13321 gttgctgcgc accacgacac agtcggtacc gaactgaagt ggtttcagac cgtgttcgcg
    13381 gcgcacacgg gagacctcgt ccagcaactc caacgcgcgc agggcccggt cgaatgaacc
    13441 cgccctgccc cggatccggt cgtgcacctc ggcgttcggc ccgtccagac tgaccacgaa
    13501 gcggtggcac acttccgcga gtcgctccac catggcccgg gtgaccggcc agccccccgt
    13561 gtagaggatc accttgatgc cgctgtcggt gagccgccgg gcgacctcgt cgatccaggg
    13621 caccgtcagc ggctccccac cgctgagcga caccacgccg gggcgcagcg cggcgatcgc
    13681 gtcggtgatg cgcagcatcc ggtcacggtc cgcctgccgg gtggggcgcc gacctgactc
    13741 ggagtagcag tgcatacatc gcagagggca cgcgtaggtg atgtcccaga tgacgtccct
    13801 gggaccgtca ccggtctgtg ccattcgacc catcgtcgcc tccgacgtcg ccgttcctgc
    13861 cttggcgcca tcctggccgg ggccctgtcg gtggccttag tcccgtcttg cggtcgtcgg
    13921 tggccgaacg gggcggggac gggagcggaa gccagcggac cgtcaggtcc tcgtcctgaa
    13981 cgccgcgatg acaccgcgga ccttggcctc ggtatcgtgt gggagcgagt cggggtgagg
    14041 tgcatcagat tgttgcggat tttgcggatc tcatcgaggc gcttggcgaa ggccccgcga
    14101 tccagtagcc agcccaactc ctcccacggc tcacggttgc ccagtacgct caggtagccg
    14161 ccgaaggtga gccggtcgaa cgaggtcagg cggcgggagc cgtcgcggtc gcacacggcc
    14221 gtgacgtcgg ccaggtcgaa acggtcggcg atgacggcac gcaggcgtcg gtcaagttct
    14281 ccgacgggca ggaacggggt ggcttgcgtg ccataggcga gagcgacgtc ggccacggta
    14341 tcgagggccg tcggtttgct tggccaagtg tgtgtcggtg ttctggcggg agtgctgtct
    14401 tggtagctgt tgtctttgct tctgtcttgg gcgcggtggt gtggggatgc agtggttggc
    14461 gccaggtcca ggccgtcgct ggcttgggct tggcgctgga gggggttatc ggcgggtgat
    14521 cttgatgccg aagtggttgg cgatgccgag ggtcatgctg atggcggcgt gtatgtgggc
    14581 gtacatctcc atgccgcggg cggtgacgag gtcgccgagg tcgaggatgt cggtccagcc
    14641 gtaggattcc agcagggtgg tggtggtctt cttcgcgtcg gagtcgttgc cggcgaggaa
    14701 catggtgtgg ttgccgccgc tgatggcctt ggggttggtg gcggtgtcct gttcctgggt
    14761 gacgaaggac ttgacgacct tcacgtccgg cagcgtgaga tgggtggagc agtgcgccac
    14821 gtcgagatcg ggcgggtccg aggaggtcgc ggcccagttg acgacgccgg tgatccgggc
    14881 atctgccggc cttgcgggcg gcacgtcgaa caacgcgttg ccgggttgga agtcccggtg
    14941 caggcccgcc cctcataagg cggcgcgggc ctgcggatca tgtcgattgc cgcggcgtat
    15001 gccgccgcgt cggcgatgcg aggactggaa gccctcgggc tggaacggcc ggatggggcg
    15061 cgagcctatc gcgcgatgtg gaacatgatg ctcgggtacc tgcttaacgc tcacccagtg
    15121 tggggcatac ggtcgaccat ggtaaggcca gcctgccggg gggagaagag ctccacggtc
    15181 gaggagtgga ccgtggagca gacttcgcct gggcgctgga acgcctgctg cacggaatgc
    15241 tccgctgacg gcttgcgagt gctgttcgcc cttgaaatcg tcccgcgttg gtcacgggcg
    15301 aaccgggtga ggcagtccgc gtctcatgag ctgcatcacc gcatggtctg acggcgcagc
    15361 ggcagttgct tggtcggctg ctgtagcaac ccgccctcgc ctgtcagttg tagtcccttg
    15421 gcctgtgccc ggcccaccag ttcgtcgatg agttggtcgt ccaccgtctt cgacggctgc
    15481 gactcaggca tctcgatgga ccctgcctcg gtcgcgtcct cagtggtcat cagtgcatct
    15541 tccttgactg ggagttgcat cgaacggttt accgtcccgg actgtcacgt cgcacccacc
    15601 agggggcgta agggattcac taagggtgcg acaagggatc gtttggatct cacttcggtg
    15661 atcattcttc tctaggattc attagttgcg gaaaatcttg attgaaatgc cgcaggtatg
    15721 ttttgtgagc gatgaggagt gagtcatgtc taagggcgag tcgttagtgg atgcggcagc
    15781 catctcccgg ttagcgaaaa gctttgatgc tcatggggcg gacctggaga gctacacgaa
    15841 ggagttccgg gcgaagaccg acgctgaggt gattgacaaa ggattcggca tcctcacgga
    15901 atccgaggaa gtaacctccg cgtacatcga gatgtccacc gacatggtgg aatcgctgaa
    15961 caccctgcgc cagcacctcg atcacatcag ccagggcctg cgcacggtcc agcagaacgc
    16021 cacagcgtcg gacgagtctc tggcggcagg ctttgaccag gggcgtcacg cgtgagcggc
    16081 gacgagtcgg tagcggaaga ggtctacgag gccggcctgg acatcatcaa ccccggcggt
    16141 gatccggacg ccctgcgcac ggcagcaaag ggctggcggg atctccacga aaacctccag
    16201 accatgttcc gggacctgga ccacgaggtg cagcggaccc tggagtccgg ctggcacggt
    16261 ccggcggcgg atgccttcgt ggagcactgg agacacctcg acgcggcgat gcaaaagagc
    16321 ttgccgcaac tgccgcaggc ggcaaaaagc ctcgacgagg ccgcggacgc catcgaggag
    16381 atcaaccacg agatccacga gatctatctg gagatcggca tctccatcgg aatatcggtc
    16441 ggcatgtcct ttgtgaccat gggcttctcg gcagccgcgg gggccgcccg cgccgcccag
    16501 ctcgccgccc gcgccgccaa actcgccaag actctcggca ccatcttgcg caaggtcggc
    16561 gaggctttca aaaccgtctc ccggctggcg aaggaacacc gtttcctgaa gaacgttctg
    16621 gtcaactggg ccagcaacac cggctccacg gtcatggcca acggcctgac cggacaagac
    16681 accaacctcg gcgaagccgt ctggcagggc gggctctccg ccgtcgccgg taccggcccg
    16741 ggccttggtg tcgccgggaa actgggcgga atgaagggcg ccatccgcgg tggagctgtc
    16801 ggcaacatcg ttggcgggat ggccgtcgac ggcgcgaaga ccgctctggg aacggacgtc
    16861 agcggcaacg agttcgccgc ggacatcatc atcaacggca tcacaggagg cgccggcggc
    16921 gcagccgtac atggcgccaa cacccatctc ccacccggcc gtgaggggcc acacttctcg
    16981 gtcgacggca tcatcaacgg aggcgtctac ggcgccggtg gggtggccgg gcagccactg
    17041 aaagatgcga tgaccggcgc caaggaagaa tcagagaaga acgtcgcgcc aggtgacccg
    17101 ggcaagaaga gcgtgaggga cgttttcggg tgagggaacg ggatcgcgcg gcggcgtccg
    17161 ccggggctgt ggcctgggcg ggtgtcgccg cgtttgtggt gtgtctgctg gtgcggaagg
    17221 tggcgcccta tccgcgctgg gatctgctgg cctgtctggc ggtctccggc gcggccaccg
    17281 tggcgtggtg gcgcatggcg cagcggcccg ccggggccag cttgaaaagg cgggccgaac
    17341 acacgcggtg gtggccggga cggcgcggcg gcatggtcgc cctcgcgctc acggtcctgg
    17401 tcatgccgct gctcctgctg atgacttcgg cggcagccac cacccccgaa ctggcagcga
    17461 tcgtccgcgg aggaccggtc ctgtcccgcg tcaccgtcca ggagatccac tccaccagcc
    17521 gcaaccagtc gcggaacttc accgagtaca cctccacggt ctccgtggcc cttccggatg
    17581 gcccacgggg cacacacctg acgacggaga gcatcaccac cggccacccg ctcaacaagg
    17641 gcgacagggt ctgggccctg cactcctccg ccggcgcggc gcccggcgcc atcctgagcc
    17701 cgagccggga cgaactgcac gcgctcctca gcggccgcat ctccgggtac gaggccgtgc
    17761 tcctggcgat gtggggctgc ttcaccgcgg tactcgccgc gctcgacctg cgggagggca
    17821 cttccctgcg ccacctcaac gccgacctca tcgcgggccg ctcgcacatg ctgcgggtac
    17881 gcatcgccgg ccccgctgca ggcttccact tcccctaccc cgggcgcacc ggcaaaccca
    17941 cccgccgccg tcagctttcc cccgcgctcc gtctgacgtt gtcagacggc cggagtcggg
    18001 atctgttcct cgaccgctgt ctcgaccccg taccgctcgc cgaggagctg tatggcctcc
    18061 acggctggct gtactggacg ccgcggccca acggacagtc gggatggacg gaacccgccc
    18121 tgttcgtcct cgatgacagc cggtacctac tgggcgcaac acccgacgga ccgcccccgg
    18181 acgcgcatgc gggcgcaccc cacggccacc ccgtcaccca gccgctcccc agccccatac
    18241 cgacccgcgc agtgggcccg tacatcctgt ggcagccaca cctccacaag ccgggcgtca
    18301 tcgccttcgt catcgccttc ctgtccgtct gcctcattac ggcgggcatc ggctacggga
    18361 accccccggc gctaggagcc tgtctggcaa ccaccgctct cgggccggtc atcggcctgc
    18421 tgctgatcgg ccaccaacgc acccgctacc tgcacagcct gcgaagcaca tgaccgccgg
    18481 cgccccgctg cgccccgcat ggtgcactgg ccgtggtgca cggcgatcgg ccgcggatcc
    18541 gctccgatgt ccatctgcag cgtccactcc ggtggcaccg cgggccgcgc cgaggctcgt
    18601 cgggtggcct cccactgctc cacctcggct atccgctggt gtacgcgctc cagctgcagc
    18661 tggaggtatg tggcgattgc gtgcagccgc aggaggtcgg aaggcagtgg aggaatgtcg
    18721 ctcacaagtt tgattctggg gctccgaggg ctccggatcc gccgaacccc tgcccgtgct
    18781 gtacgcgccg ctgtacggtc ggcgtatgtc gaagccagta acgatccggg tcgatgacca
    18841 gctccacgcc ctgctcaagg aacgcgccga agccgagggc accacggtga ccgcgctcat
    18901 cgcccgcgcc gcgcacgacg ccgtccgcga cccccgcctc gaaggtgccg cggaggtctt
    18961 ccgctccttc gtcaacgacc acgccgacgc gttcgacgcc gccttccctg aagacgcccc
    19021 gtcccgactc gacgcaccgg gacgggccgc ctgacgtgga gctctacgtc gacattcgct
    19081 ggctccttaa acgccaggcg gaggtcctcc ccaagcaccc gcacatccac gacttcacca
    19141 gcctggtggc cgccgtagga cgccaccgcg tcaacatccc cagagtcggc gccaccgtcg
    19201 acaactcttg gcgcgccgcc accctgatgc acaccgtcat ccgcctgcgc cccctgcccg
    19261 cccgcaacgc cctgttcggc gccggcctcg tcgtggcgta catgggcgcc gccggcgaag
    19321 gcatcgacgc gccctacagc gcgctgatcg acctcgcccg cgacatcgac gccggccgtt
    19381 gcgacacgta cgacgcggcc gatcgcatcc gttcctggcg gatctgacca ctaccgcgcg
    19441 gtcccggaat ccgcgggact ggcgagggcc accagcgggc cccgtccgag ctgcgagacg
    19501 aagctcgcgg ccgtgcttcg gcaccacttc cgcgctatcc cgcccggggc aggctggagg
    19561 agcgggaggg ggccggcatg cgtgtcccgg acatccggat cggcgagacc taccaggtga
    19621 aggtccccca gcggattccg cccgccctgc gccgcgtccc gcacagcccg acgcgggccg
    19681 ccgacgatct ggaaggccga tagacacctg cccgagaagc ggccctgagc ctgtcgaggg
    19741 cgccatcgac gatcggggaa gcggcaccca gccagccgcg cgcacggagt gtcggagcgt
    19801 cttgtgccat cagtgtcaga actggtcggc gcgcatcggg acgagttcgg cgacctcgaa
    19861 caggtcggtg tcagggtgca gttcgaggaa gcgtgccagg acctgggcgt gcgcctggtc
    19921 ggcgaacagg tcctgggcga gggggtcgtc gtcgagccag cccatggcca tgtgggcggc
    19981 ggcgtggagg gcgtcctgct cgctggggta ggaccaggtg ctcagcgagc gactccgctc
    20041 gctgcggtgg agaaggaccc acaagcctcc gggctccgtc gtcaccgggg cgtggcggag
    20101 gggctggcag gtgcgacacc aggaggcgtt ggcagccacc cgctgctccg gccagatgta
    20161 gcccagggac tgctcaggcc gcggcgcagc agccggccgc gcggacaggg accgcggtgc
    20221 ctccgtgagc gggacaggga ccaggtaggc ggtccgtttc cgtggcttct tgaggagatg
    20281 gtgcgcagga cgccacaaca ctggcggcca cgcctcgtcg agtgagcggt ggtggacgta
    20341 gatggcggga tggctgccgt ccgcgaggac cccggtgttc gggatctgct cctcgccggg
    20401 tggcaacggg agcaaccagc cgccagagtc ctggagccag gactgcccgc aggcatcaca
    20461 ccaccgcacc gcggcatcct gctcggcacc gcggcctcga cgccctccgc cagcaccaac
    20521 tcctcggaca tcgagaacac ctgctcctcg atgaccagca gcaccctgga cgcgatcacc
    20581 tgccgcgccg agtccaccgc agctccgctc agcacgcctg ccaacacgtc gacggcccgc
    20641 accacgagcc gctcctgttg cttgccccag ctccccaccg ctcggccctc cctgcccgat
    20701 gccgcttccg tccgtacagg tgccatgatc ccggccacgt catcggagcg cggctgaact
    20761 gccccagccg gatgagatcg agccggtccc cggcgacacc gctggcccca gctgcgtcag
    20821 tgcgccgacg cgcccgaggg cctccagggc gaaagtgtcc tcgcacggct cgcccgcgtc
    20881 cgggccgggc aacgcggtga tcgggacgac gatccgttcg acgacgtcga cgagcagcgt
    20941 gggcatccac ggtcagcgaa gagggttgca ccggcaggcg gctgaaccgt tggctggacg
    21001 gttgcaccca gcggggggcc gcaggttgcc ggaggtatgc ccctgactga tcgactgtat
    21061 ttccgcaggc catcccccat gggcaagccg gtacgcgaaa acgacacccc ttcctcacgc
    21121 gattgccgag gggagagatc tccttcgagt ccccggagca gcgccgcgcc ttggtcgact
    21181 ccctgggtgg ctggggcgcg gcgggtggaa cgtcagcttg agcggcacga gggtccgggt
    21241 gagccgggcc catcatgggg gcgagcggac cactctggcg agcgaccagg ctgtgccgcc
    21301 ggtcaggccg gggcgggctc gagagagcgg cgagcgggga ccgccggcct ttctcgaccg
    21361 tgcgcagctg ctcccagtcg acctcggtcc gcgtggcggg cagggcgtcg acgtcggcgg
    21421 ttcggtagat caccagtggt cggcggggac ggccggggtc atctgttcgg gcttcgcggg
    21481 cagcggcttg cagtcggcga aggtgtcatg cgggccgccg agggggttgg ttgccgtagg
    21541 cgccgccgcg tttgactgtc caccagcagc tccccgcccc tcatggccgc ggcgaggcgg
    21601 cggccatgag ggcacgtcca gccgtggtga gctcgtgcgt ggccgtgcga ccggcccggc
    21661 tgctgtcgat caagccggcg tctcgcagga ttgccaggtg ttcgctggct gtcgggggag
    21721 tgacgttcac cagtctggcc acaacggtcg tctgcagcgg ggtggtgagc gcggccagga
    21781 tcctcgatcg agtcactccc agaagacggt caagggacct cggggtagga ggtgccgccc
    21841 agaggtaccg cccggatgcc gggtaataga tcgtcggagt ccagtggtct gaggtggtgc
    21901 attgcatccg gtcggtgatg aacagtgacg gtacgagaat gagtccttca gggcagtcga
    21961 cgtcgatgtc gacggtcttc tcgacggtga cggagtcgcc ttcgcacgca gcggaggggt
    22021 gcaggcgcgg aaggacagcg cgcagtccct cgcggttgac ctggatggct cgatccagca
    22081 tctcggcacg cagcgcctgt cgcatggacg gccattccgg ttctacaact gccttccaga
    22141 ggcggtgcag cgcatcggcg gcctcggacc tggctcggtc ggggtcatcg agcagtcggc
    22201 ggcccagttc ggccccgcgc cctttcgttg cgtcgaccag ctcggcgtac gtctggtccg
    22261 cgggcgcggc gaggagggca tccatgcctt cttcgaacgt tggctcactg gacatcggcg
    22321 atgggtcaag gaagtcgggt cgatacgcgc catcggccat gaagaccgtg agcgccccca
    22381 ggtcggggag cgagagacgg cggcgacggc gaagccacgg gtggaatatc gggtgacgct
    22441 gcggttcggt caagagctgg gcaagactga ccacttcgtg gatcggcgac atcgcccacc
    22501 gcacactcgc agcaccagcg cccaatcggt agcggatcat cgcacaattg ttaggccacc
    22561 gccgaagtga gcgcgagcag aacggcgaag ccccgagact cgggtcatga ccgacacgga
    22621 gtcgattgcc cggtgttcca aggaacccga gcgagcccaa cagacgcgaa cgatccggct
    22681 gggtgccggc ggatcgacca tcgaagtcct cgcgggtcca gcggagacca gcgggatcgt
    22741 gagcatctac cggtggc
//
