LOCUS       NZ_CP054019            21059 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. A1-5 chromosome.
ACCESSION   NZ_CP054019
VERSION     NZ_CP054019.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. A1-5
  ORGANISM  Streptomyces sp. A1-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9459690)
  AUTHORS   Dashti,Y., Sumang,F.A.M., de los Santos,E.L.C., Alcantara,E.P. and
            Challis,G.L.
  TITLE     Structural revision and biosynthesis of polyketides FXJ15321 and
            FXJ15322 from Streptomyces sp. A1-5
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9459690)
  AUTHORS   de los Santos,E.L.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2020) Warwick Integrative Synthetic Biology
            Centre, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL,
            United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUN-2019
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:28:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,328
            CDSs (total)                      :: 8,230
            Genes (coding)                    :: 7,847
            CDSs (with protein)               :: 7,847
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 383
            CDSs (without protein)            :: 383
            Pseudo Genes (ambiguous residues) :: 0 of 383
            Pseudo Genes (frameshifted)       :: 156 of 383
            Pseudo Genes (incomplete)         :: 280 of 383
            Pseudo Genes (internal stop)      :: 26 of 383
            Pseudo Genes (multiple problems)  :: 73 of 383
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:08:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9164278
            Orig. end                         :: 9185337
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Philippine National
            Collection of Microorganisms.
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="40"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11059)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(306..521)
                     /locus_tag="HRD51_RS40235"
                     /old_locus_tag="HRD51_39710"
     CDS             complement(306..521)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS40235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_39710"
                     /product="hypothetical protein"
                     /protein_id="WP_205367696.1"
                     /transl_table=11
                     /translation="MKEKSSGAHQKPASRRVLLSTVVALVVGGVIWVATWKLEWWSPGL
                     GLLTAKVAVVISAGVVAFVAGRAKRR"
     misc_feature    complement(523..539)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    699..712
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.22"
                     /tool="antismash"
     gene            714..1244
                     /locus_tag="HRD51_RS40240"
                     /old_locus_tag="HRD51_39715"
     CDS             714..1244
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024559.4"
                     /locus_tag="HRD51_RS40240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39715"
                     /product="DUF3995 domain-containing protein"
                     /protein_id="WP_235095690.1"
                     /transl_table=11
                     /translation="MHTDRQDCRTTAGVWGRIACVWAVAFAALHFYWAVGGSWGLSVSA
                     GPLAGERPAWFVAVGLWGVGALCLVGGLLGWLLARPWPGGLVGRLVKALGWCVCAVLLV
                     RGIAVEILLLLDTAGRAVGVSPEQRLWTLVLWNPWFLVGGLVFGLAAREFGRVTGRATE
                     LPGGPVGAREQDG"
     misc_feature    complement(1407..1421)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.98"
                     /tool="antismash"
     misc_feature    complement(1414..1428)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.75"
                     /tool="antismash"
     gene            1521..2015
                     /locus_tag="HRD51_RS40245"
                     /old_locus_tag="HRD51_39720"
     CDS             1521..2015
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013936.4"
                     /locus_tag="HRD51_RS40245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39720"
                     /product="hemerythrin domain-containing protein"
                     /protein_id="WP_235095691.1"
                     /transl_table=11
                     /translation="MTPHGRLKAFGNQLVEVHLWLREELAALREDVDSYLAGGTRLREL
                     RTHCLTFCSALNRHHTGEDQVAFPEMAEIYPELHPVLDELRRDHQLVEDSLRRLDALVG
                     ELDQAKDPVEVRREMDSLAALMETHFVYEEKRIVAALNALNVPDWEVSMPDFLLAGDAE
                     H"
     misc_feature    complement(2113..2126)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            2232..3110
                     /locus_tag="HRD51_RS40250"
                     /old_locus_tag="HRD51_39725"
     CDS             2232..3110
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004986602.1"
                     /locus_tag="HRD51_RS40250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39725"
                     /product="virginiamycin B lyase"
                     /protein_id="WP_235095692.1"
                     /transl_table=11
                     /translation="MSDRDGGPYAITTGPDGALWFTLVHSGRIGRLVPGGELTSYQLDP
                     SCRPTIIVSGPDGALWFTEYQANRIGRISVDGTVDEFTLPTPDRGPFGIASGPDGALWF
                     TETAADRIGRITPDGHITEFPLPVSGAFPSAITAGADGGMWFTLNQAHAIGRIGTDGSV
                     SIHPLPTESAAPVGITGGPDGALWFVEIAAGQIGRITTDGRIAEFPLPDRSARPHAITT
                     DGNGIAWFTEWGGNRVGRITPDGAITVHDLPTPGSEPHGIALGPDNALWTALETGALAR
                     IVPGRTPTNNA"
     misc_feature    complement(3114..3129)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     gene            3125..>3301
                     /locus_tag="HRD51_RS40255"
                     /pseudo=""
     CDS             3125..>3301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018518573.1"
                     /locus_tag="HRD51_RS40255"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTVTFSHTIIVSEDRNESARFFRELFERPQAPSRGPFVNVQLDEG
                     VLLQFAEPPVTEIQ"
     misc_feature    3126..3140
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            complement(<3491..>3802)
                     /locus_tag="HRD51_RS40260"
                     /pseudo=""
     CDS             complement(<3491..3802)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007824919.1"
                     /locus_tag="HRD51_RS40260"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLESLRPSPACVVSRTNDLLAANRPGLRLFAGITDWPPERRNLTR
                     YMFLHPMGRRLYRDWEKMAGHSAAHLRAMAGADPDMPELAQLVGELVVKSPEFARLWER
                     "
     gene            3949..5241
                     /locus_tag="HRD51_RS40265"
                     /old_locus_tag="HRD51_39735"
     CDS             3949..5241
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268394.1"
                     /locus_tag="HRD51_RS40265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39735"
                     /product="MFS transporter"
                     /protein_id="WP_235095693.1"
                     /transl_table=11
                     /translation="MLGFFVITVDVSGVNVALPAVGREFGGSLAGLQWVADTYTLMFAA
                     LMLSAGALSDAVGARCAYGWGLGVFTVASLACAAAPTLGALTAARVVQGSAAAVMVPAS
                     LALIRQAFPDRVARARGIALWTLGGAVAIAAGPVLGGLLTTTWTWRAVFFLNAPAGIAA
                     CLTLLRAAPSPRHRAPFDLPGQVTAVLALAGLTFAVIEGGHRGLTGTVLTAVGVAVASG
                     VGFVVVEARRRTPMLPPKLFRQRGVTVPVVAGFAVNAAFYGGVFVLSLFFQQQRGQSAF
                     SAGLMFVPMAAITAVFNYLSPRAVSRYGPRAVIVVGLLTVALGCGALLAVDKGTPAWLT
                     ALSMTPLGFGGALAMPAMTSLLLDSVAAARVGTAAALLNTSRQTGGALSIAVFGALIAQ
                     DFATGMRQSLLLAACLLVATALGATALLPRR"
     gene            5326..6255
                     /locus_tag="HRD51_RS40270"
                     /old_locus_tag="HRD51_39740"
     CDS             5326..6255
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1031: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF015431.4"
                     /locus_tag="HRD51_RS40270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39740"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_235095694.1"
                     /transl_table=11
                     /translation="MDARSLPNLASLRSLEAAARLRSYTLAARELHVTHSAVSHQIRQL
                     EAQLGVALFARSGTQMLPTPVCARLAARLRRSLGDLVEALGEAMGEAGASSMPLELSVM
                     ADFANVWLIPRLADLARAHPQIELSVRLHTGMAPPDPRSVDLGIWHRPVEAHDHRSVRL
                     LEDQVIAVCSPGLTARHPGLTLGTLPQAPLLRFALRSWKEFFAAAGIDAGEPAHGVIYS
                     DAEALLRAALAGQGVAMVRRQMADAYLGRGDLVRIGDVEIRDQLDYFLSWREGHPRAST
                     IHTFHDWLRQQLTAAPEPLGTGDDGRRT"
     gene            complement(6713..7333)
                     /locus_tag="HRD51_RS40275"
                     /old_locus_tag="HRD51_39745"
     CDS             complement(6713..7333)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF037625.4"
                     /locus_tag="HRD51_RS40275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39745"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_205367681.1"
                     /transl_table=11
                     /translation="MSDDLRALPLRERKKLRTRRTLAETALRLFTERGYDATTLDDLCD
                     AVEVSKRTFFRNYRSKEDVALASDSDLWSTYLDHVAALKLDGPLLAVLRTALDTTLGAM
                     DPDWDRRFLATRELSDGVPALQAHSLGYCHDTTGAIVRTVTERSGADVDGVRLRLTVEI
                     FVAAWHTASLHWTAQGGRGGRDGLTKLVEETFAKIPDALTCSA"
     misc_feature    7388..7400
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            7451..8956
                     /locus_tag="HRD51_RS40280"
                     /old_locus_tag="HRD51_39750"
     CDS             7451..8956
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018101566.1"
                     /locus_tag="HRD51_RS40280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39750"
                     /product="MFS transporter"
                     /protein_id="WP_235095695.1"
                     /transl_table=11
                     /translation="MTTVPTGRSRPTIALLVVLLAFVTVPMSISGAAVALPDIGEDLHA
                     AGASLQWVMNAYNLTFASFMLVAGSTADLVGRRRTFATGATVFAIGSLVAAVAPGIVLL
                     DIARALSGIGAAGVFASGGAILATTFDGAARTRAFAALGSAAGLGLAAGPTLAGWLVGA
                     LGWRATFGLHAVLVVVALAGVGFVAESRAEQRPRLDVTGAVVFVAGLGLLVLGAVQGPE
                     WGWASPGVLALLVVGVGLLVLFVVLQARSTAPVLDLTLVKNRRFLALCMVPVVSTFGFV
                     TLLTYLPTYLVGASGFSPQRAGTVLLLMTAPVLLAPPLAGGLVNRGVSPRTLITLSLVM
                     FAGGNAWLSVIGPSSSVAVIAGPLLTSGLGAGLSFGVGDGAAMSLVEPERAGMATGFLN
                     TLRIGSEAIVIAVYGAVLVSLIGTRVGSQELAARVAAGDLSGSDPGVLADGFTHALHIA
                     LYGTAAVCAIGAVVIAAALAPPRRAAAAAPSVPQDAQLTTKAG"
     gene            complement(9090..9968)
                     /locus_tag="HRD51_RS40285"
                     /old_locus_tag="HRD51_39755"
     CDS             complement(9090..9968)
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574303.1"
                     /locus_tag="HRD51_RS40285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39755"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_235095696.1"
                     /transl_table=11
                     /translation="MTITHADTAARTPVPTQSTYQSRVADYWNAEENPVNLELGKIDDL
                     YHHHYGIGDADWSVLDEPDPDRRRERVTGELHRLEHAQAELLASHLGDLTPSDRVFDAG
                     CGRGGGSVVANLRYGCHADGATISAKQAEFANEQARKRGIDDKVRYHHGNMLDTGFTSG
                     AYAASWNNESTMYVELDLLFAEHARLLRRGGRYVTITGCYNDAYGRASREVSLINAHYI
                     CDIHPRSAYFNAMARNRLVPVHVEDLTETALPYWELRRKADHLVTGIEDTFLNAYRNGS
                     FQYLLIAADRV"
     gene            complement(10001..11059)
                     /locus_tag="HRD51_RS40290"
                     /old_locus_tag="HRD51_39760"
     CDS             complement(10001..11059)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538318.1"
                     /locus_tag="HRD51_RS40290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39760"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_205367677.1"
                     /sec_met_domain="T1TS (E-value: 7.1e-51, bitscore: 172.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPPSTDSGFTMPGPPNLVRDLRARNGGAVPGLKYRPAVPADPE
                     KAKEIDRRLEEWARGLDLFPAQWTGDFAEFQCGRAVVLQHPGAVDLERLTVAGKFLLAE
                     NVVDSCYCEEDEGRGASRSGLAGRLILAQSALDPFHGTPALEEEWHEGMQADGPLRSYY
                     WAMKDLAAVSTPSQADRFVHDMARLHLGYLAEASWAETRHAPQVWEYLVMRQFNNFRPC
                     LSLVDTVDGYELPEALYARPEVQRVTALACNATTIVNDLYSFTKELASDPTHLNLPQVV
                     AANDKRGLKAAYLKSVEIHNEVYEAFEAESAPLAALSPLLEKYVRGLTDWVSGNHEWHA
                     TNTDRYQLPNYW"
     gene            complement(11078..12520)
                     /locus_tag="HRD51_RS40295"
                     /old_locus_tag="HRD51_39765"
     CDS             complement(11078..12520)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016576907.1"
                     /locus_tag="HRD51_RS40295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39765"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_235095697.1"
                     /transl_table=11
                     /translation="MSTPDSVTGSVTDEPVLDPAADSARTSLSTQAARQLATTTKTVPQ
                     MQAITSRWLLKMLPWVDVKGGTYRVNRRLQLRVGRGRVQFEQNGADDIKVIPQTLTELP
                     VLRGYDDIEVLKEIAGRFRVREVRAGQVLFEAGQPATEAFLVVHGRFSRYKPGKYGEEE
                     IIGVVTDGDQMGDEAIGQPEPRWLSSVRADTEGVVMVLPWDVVEEFTGRVPSLAAHLSA
                     YAEQQRLPMNRKGEADVPVQAGHVGEPMLSGGFVDYELAPREYELSLTQTVLRVHSRVA
                     DLYNEPMDQTQQQLRLTVEEIRERQEWELVNNREFGLLHNADYGQRISTYTGPPTPDDM
                     DELLSMRRKTRLFLAHPKAIAAFFRQCNKRGLVPGTADVDGHEVPAWRGVPIFPCGKIP
                     ISGTHTSSIVALRTGEADQGVVGLYQTGIPEEFQPGLNVRFMGIDQAAIIKYLVTAYYS
                     QAILVPDAVGILENVQLGRSAD"
     misc_feature    complement(12778..12792)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.85"
                     /tool="antismash"
     gene            complement(12908..15733)
                     /locus_tag="HRD51_RS40300"
                     /old_locus_tag="HRD51_39770"
     CDS             complement(12908..15733)
                     /EC_number="3.4.24.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539346.1"
                     /locus_tag="HRD51_RS40300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39770"
                     /product="M48 family metalloprotease"
                     /protein_id="WP_235095698.1"
                     /transl_table=11
                     /translation="MTASSFATLTSVLDQLSVLSESGRPGAGLYGTPSCLYAAGFDPSS
                     SDLGNLRATMSRPDALLKCLGDRPVGYRALIATAVLLAVAALVYWWMPKARDWRRRMVP
                     VEAVDADGTLRAELAALCERTGVRSSLRFRVDPARMTSGASAYGRTGNYTVCLHVGLLA
                     RRGTDPEGFRAVVLHELAHVHHRDVDYAYASTALWRVYVLLALLPHFAGIGWIFLLAFS
                     GTDSPWWPGAAPTLLAEVFVGLLLTALLHLARADLLRRRELHADLQAVAWGAHPGSWDR
                     SDPAGAVAPALRRLTTLLRTHPSWAERRGVLADAGRGFRVSPLEMFLTGASASLLYSAL
                     GLTSSALLPETVGWSYALVATVAVVTPVLCAGLGLPLVRASDPARGYVRSAVASGLWLG
                     CGLLVGEVTASGQYRLDVLVSQPEYLLAFLFIGAVPALWWSHSLQLALGLPRRGQRWAA
                     AVVCALVTAAVLLTGLLWWRLGGERIAMGYGDAGEGLAAMYARMVPGNWRDYGLDLSTL
                     TVGMPLLTPLSEERLADATAYLMWFVPLVLLLVRGPGLRMRRTLGAGVAGGLVSWAGLA
                     AAMYAMYLQRPATLKERAGPFLVVHAWWMIVTVLAACGLTAALVAAYSRHHWLLRALIA
                     AQITQLMAYAGVFVLYSADGCLGPLNTVLDACQWRPHNGLTVDKGVTHLTLTGAVVGAA
                     CAALMGAGAAWAARRLRRRPATSDLPAVPAPTAPRRRRWALLTTGTVLALGVPALLLTV
                     VTILQTTSSPSSVVAGSSGDTAATGDKKPDRLSPGQAAKLHTWQVWSWMYHGGALHAQQ
                     IETAWAALAHRILLLSAQSRDKNGQVWVDEKRFHGPCGTLGKRVEEAQGYFRVPDPDLQ
                     TSWSDTLGQLRRGAQKCQQATVPPTGETRKAEEQRGALFTTSLNEIAKGMRSLSTTLQD
                     ITKAATSKTTK"
     gene            16115..16744
                     /locus_tag="HRD51_RS40305"
                     /old_locus_tag="HRD51_39775"
     CDS             16115..16744
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016577571.1"
                     /locus_tag="HRD51_RS40305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39775"
                     /product="PepSY domain-containing protein"
                     /protein_id="WP_205367665.1"
                     /transl_table=11
                     /translation="MKRHLVIAAAAAAVLAVGTVTAVAVSGSGAGGSAPTAAPAAGNGR
                     QDTEDLREARAARVTAPQAAAAALKAVPGKVSGLDLDQDRPGLVWDVDVLGKDGRWHEI
                     TLDARTARVLEQRIDGGNDDDHGQERAALDTARADAAGVARTAAAGHGTVTSVELDDDH
                     RAQAVWEVETITEDGMEHKLLVDPRTGALRTAPTHDAYDDNEGGDD"
     gene            complement(16837..17973)
                     /locus_tag="HRD51_RS40310"
                     /old_locus_tag="HRD51_39780"
     CDS             complement(16837..17973)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016572986.1"
                     /locus_tag="HRD51_RS40310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39780"
                     /product="MFS transporter"
                     /protein_id="WP_235096225.1"
                     /transl_table=11
                     /translation="MLAAFTFNTAENLPIGLLELISKSLRVPVAAVGLLVTGYGVTVAA
                     ASLPLAHATRTVPRRHVLTGLLAALVVSSLVAAQATSYWLLLVARLLTALAQALFWAVT
                     GPVAVGLFAPEVRGRVVGALSVAGSLALVLGVPLGTWLGQHSDWQVPVALLAGPGLCSL
                     VTIAAVLPTSPPEAEPAAYGTSPDTRRFGTVLAAGALSATGAFAGYTYIVTFLLDVSGF
                     APNTVGVWLVVFGVACLAGVGITGALLDRFPHAAPVTAVATQAVGMLGLFAAGTHQVAA
                     VVFLVLTGGALGPVFMTAQNAMLHCAPGRTDIALAANSGSYNAGIAAGAALGGLVLPLA
                     GVRGTFLAGGLLTVLACAVLLGGRWRLRRWGPGCGRRG"
     misc_feature    complement(18183..18198)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            18291..18785
                     /locus_tag="HRD51_RS40315"
                     /old_locus_tag="HRD51_39785"
     CDS             18291..18785
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538104.1"
                     /locus_tag="HRD51_RS40315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39785"
                     /product="VanZ family protein"
                     /protein_id="WP_205367664.1"
                     /transl_table=11
                     /translation="MSFPLALSTGVLGCGVIAVVTFLIGRPRRTSHRVCSALGWLWVAG
                     VVGLTFGTRSGGGQAMNLKLLDLSNPADTWDFFLNVLMFVPGGLLLASAGVSLLTATTV
                     GFLGSLAIETTQYLTASGRTADVNDLLANTLGCVAGYACAAAVRAAFRRTTATAGPRLR
                     A"
     gene            complement(18824..19699)
                     /locus_tag="HRD51_RS40320"
                     /old_locus_tag="HRD51_39790"
     CDS             complement(18824..19699)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539790.1"
                     /locus_tag="HRD51_RS40320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39790"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_205367663.1"
                     /transl_table=11
                     /translation="MLDVRRLRLLRELAHRGTIAAVAEALSFSPSAVSQQLSLLERETG
                     VPLLKRTGRRVALTPTGQNLVRHAEDILERLEHAEAELAAVRSGLAGPVRIGSYPSATR
                     AIIPAALAALAREHPMLEARVLDVDPVGVAAALRAGELDLALVHEYDVVPAEPQPGLTG
                     EELFTEPMYLAARTPSSLNDHSTSPWIMAPPGRLCRTMAMRACQAAGFAPHVRHEVDDF
                     ATVLALVALGQGVALIPHLGATAPPPGLSLTRLPMSRRTRTVHRAGAADHPAVTTVTAA
                     LRMAVPPELL"
     misc_feature    complement(19690..19710)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.1"
                     /tool="antismash"
     misc_feature    complement(19728..19743)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            19760..20659
                     /locus_tag="HRD51_RS40325"
                     /old_locus_tag="HRD51_39795"
     CDS             19760..20659
                     /EC_number="4.3.3.7"
                     /GO_function="GO:0008840 - 4-hydroxy-tetrahydrodipicolinate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539791.1"
                     /locus_tag="HRD51_RS40325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_39795"
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="WP_235096226.1"
                     /transl_table=11
                     /translation="MLKGMELHGIYVPLVTPFAQDGEVALGALESLARSVLAEGAAGLV
                     ALGTTGEPATLSPEERRQVVEVCARVCRERGARLIVGAGGSDTGRSALALEDLAQVADA
                     ALVPVPPFVRPSPGGVLAHFAHLTEHSPVPLVVYHIPYRTGQALGAGTLRRLCRMPGIV
                     GVKLATGSVDEDTIELMGDLPPDFAVLAGEDAFLAPLLALGATGGILASAHLATAHFVE
                     LLNDWDKGNLVHARALGHRLAALARAVFAEPNPAVVKAVLAAEGRIPTPAVRLPLLPAS
                     QTAAARASACLDALSEGP"
     gene            20808..20999
                     /locus_tag="HRD51_RS40330"
                     /old_locus_tag="HRD51_39800"
     CDS             20808..20999
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS40330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_39800"
                     /product="hypothetical protein"
                     /protein_id="WP_205367661.1"
                     /transl_table=11
                     /translation="MHRGTRRIVAVVIGAVALVGLMSPQASAGGGSPVKRAIMKLGLPP
                     DGIGTLLIDAAGAAAAIV"
ORIGIN
        1 acggccacgt cgggccggtg ctcgaccacc gcggcgagca gctcgggtgc cgtcccggcg
       61 gtcgccacca cctcgcatcc gcgggcgccg agcagctcga ccatcccgtc acggagaacg
      121 acggagtcct cggccagtac cacgcgcagg ttcctgttga tcaccacgcc attatcgggc
      181 cgaccgacgt ccgtcgccgg ccggtgatcc ccgcacggga aacccccacg ccggaacggc
      241 gagtcacccg aggccgatcc ctcccgcctc gacccgctcg tcacgcaggc cgccgctctg
      301 tcacatcatc gacgcttcgc acgcccggcc acgaaggcca cgacccccgc cgagatcacc
      361 acggccacct tcgccgtcag caggccaaga ccggggctcc accactccag cttccacgtc
      421 gcgacccaga tcacgccccc gaccaccagc gcgacgactg tggacaacag gacgcgtctg
      481 gatgcgggct tctgatgcgc accgctgctc ttctccttca catgcacatg ttaagagcaa
      541 gttcgcgaac cgcgctcggt tctccgccat ctcgcatctc cgccatctcg cagtcacgcc
      601 acctcgtatc caccccacct cgcatccacc gggtacagcc agcctgccgg agcttgccag
      661 tggtatcggt ggtgctggcg attgcgcgcc atggcagtgg catgctcctt gccatgcata
      721 cagaccggca ggactgcagg acgacggctg gggtgtgggg gcggatcgcg tgtgtctggg
      781 cggtcgcttt cgctgcgttg cacttctact gggcggtggg cggcagctgg ggactgagtg
      841 tctcggcggg acccttggcc ggggaacgcc ccgcgtggtt cgtggcggtg ggcttgtggg
      901 gtgtgggagc gctgtgcctc gtaggcggtc tgctggggtg gctgctcgcc cgtccgtggc
      961 ccggtggcct ggtcggacgg ctggtcaagg cactgggctg gtgtgtctgt gccgtgctgc
     1021 tggtacgcgg catcgcggtt gagatactgc tgctgctcga cacggcgggc cgtgcggtag
     1081 gcgtcagccc ggaacagcgg ctgtggacgc tggtgttgtg gaatccctgg ttcctggtcg
     1141 gcgggcttgt cttcggcctg gccgcacggg aattcggacg ggtgaccggc cgagcaacgg
     1201 aactgcctgg tgggcccgtc ggcgcacgag agcaggacgg gtgagcggtg gatggcgagc
     1261 cggagaccgg tcggcggagg cgaaggctgc cgccgctgac cggcagccgc gccgggactc
     1321 ggcgaaagcc caccgtggta gggagagcgg cccaccacga gtcgtgcgtc cgatcagggc
     1381 gaccgctcgt gcctgtgcct gcccgctgaa cttgattgac agaccatttt tgccttggta
     1441 ggaatttggt cagcgtcgcg gtgtacccgg caaagagacc gtcgaggaca tggaggcgcc
     1501 gaaccaatgg gacaaccttg gtgacacccc acggacgcct gaaggcgttc ggcaatcagt
     1561 tggtcgaagt acatctctgg ctccgcgaag agctcgccgc actgcgtgaa gacgtcgact
     1621 cctatctcgc cggcggcaca cgactccgcg agttgcggac gcactgcctc accttctgct
     1681 cggcattgaa ccgacaccac accggcgagg accaggtcgc attccccgaa atggctgaga
     1741 tctaccctga actgcatcct gttctggatg agttgcgccg cgaccatcaa ctggtcgagg
     1801 actccttgcg acggctcgac gcgctggtcg gcgagctgga ccaggcgaag gacccggtcg
     1861 aagtccggcg cgagatggac agcctcgcgg ccctgatgga gacgcacttc gtctatgagg
     1921 agaagcggat cgtcgctgcg ctcaatgcgc tgaacgtgcc ggactgggag gtttcgatgc
     1981 cggacttcct gctcgccggc gacgcggagc actgaccggt tcagcggccg taccgctgcc
     2041 gtcgcggggc gccatccgcc ccggacgcgc cgcccgtcgc tcggcggcgt cgagcgctct
     2101 gcctggctgg tctgcacgcc catacgcccg cacgcccgca ccgtcctgaa cggccacccc
     2161 ggccgacaac gacagcatcc ccgaatctcc aggagaagac attgacacag gtcgccatcg
     2221 aagagtacgc agtgtccgac cgtgacggtg gaccgtacgc gatcaccacg ggaccggacg
     2281 gtgcgctgtg gttcaccttg gtccacagtg gccggatcgg aaggctcgtc cccggcggtg
     2341 agttgacgag ctatcagctc gacccgtcct gccggccgac gatcatcgtc tccgggccgg
     2401 acggtgcgct gtggttcacc gaataccagg ccaaccggat cggaaggatc tcggtcgacg
     2461 gaaccgtgga cgagttcacg ctgcccaccc ctgaccgcgg gccgttcggc attgcctcgg
     2521 gaccggacgg tgcgctgtgg ttcaccgaga ccgccgccga ccgcatcggc cgcatcaccc
     2581 ctgatgggca tatcaccgag ttcccgctcc cggtcagcgg tgcgttcccc tccgcgatca
     2641 ccgccggagc cgacggcggg atgtggttca ccctgaacca ggcccatgcg atcggcagga
     2701 tcggcaccga cggctcggtc tcgatccacc cgctgccgac cgagagtgcc gcaccggtgg
     2761 ggatcaccgg aggaccggac ggcgctctct ggttcgtcga gatcgccgcc ggccagatcg
     2821 gccgcatcac caccgacggc cgcattgccg agttcccgct gcccgaccgc agtgcacggc
     2881 cacatgccat caccactgat gggaacggca tcgcctggtt caccgagtgg ggcggaaacc
     2941 gcgtcggccg gatcactccg gacggcgcca tcacggtcca cgacctgccc acgcccggca
     3001 gcgagccgca cggcatcgcc ctcggaccgg acaacgcact gtggaccgcc ttggagaccg
     3061 gcgcactggc ccgtatcgtc cccggccgca caccgacgaa caacgcctga gaggagaccc
     3121 ttgcgtgacc gtcaccttca gtcacaccat catcgtctcc gaggaccgca acgagtccgc
     3181 gcgcttcttc cgcgagctgt tcgagcgccc ccaggcaccg tccaggggcc cgttcgtcaa
     3241 cgtccaactc gacgagggcg tgctgctgca gttcgccgaa ccacccgtca ccgagatcca
     3301 gggtgacacc ggccgcacgg cgagatcgcc ggcccgccct tccgcgcggt catccggatg
     3361 tgggcggggc cggcggtgtc gtcgagcggg gcctgatcgg ctcgtggtcg cgtcatgggc
     3421 tctggaacaa ctcgccacga ggggacgtgc ggcgtcggtt gaggaggacg acaccgacga
     3481 gggtgacagc ccgctcccac aggcgggcga actccgggct cttgacgacg agttcaccga
     3541 cgagctgggc cagttccggc atgtccgggt cagcgcccgc catcgcacgc aggtgggccg
     3601 cgctgtggcc ggccatcttc tcccagtcgc ggtagagcct gcgccccatg gggtgcagga
     3661 acatatagcg ggtgaggttg cggcgctccg gtggccagtc cgtgatgccg gcgaagaggc
     3721 gcaggccggg tcggttggcg gccagcaggt cgttggtgcg gctgaccacg catgccgggg
     3781 agggacgcag cgactccaac agcgcgagga tctgcccccg gcgggcgcgg aaccggaacg
     3841 ggcggaggaa cagacgcagg accagataca gacatcggcg cgcaggcggc tctccgcgat
     3901 gcgccggagc cgcgaccggg tgcggccgta gcggctctgg ttgccgcggt gctcggattc
     3961 ttcgtgatca cggtcgacgt ctccggcgtc aacgtcgcct tgcccgccgt ggggagagaa
     4021 ttcggcggtt ccttggccgg gctccagtgg gtcgctgaca cctacacgct gatgttcgcg
     4081 gcgctgatgc tctcagccgg tgcgctctcc gacgcggtgg gcgcgcggtg cgcgtacggc
     4141 tgggggttgg gcgtcttcac cgtcgcctcg ctggcctgcg cggcggcgcc gacgctgggt
     4201 gccctgacgg cggcgcgcgt ggtgcagggg agcgcggcgg cggtgatggt gcccgcctcg
     4261 ctggcgttga tccggcaggc gttccccgat cgggtcgcgc gagcgcgggg catcgccctg
     4321 tggacgctcg gcggcgcggt ggccatcgcc gctgggcccg tcctgggcgg gctgctgacc
     4381 acgacgtgga cctggcgggc ggtgttcttc ctcaacgcgc ccgcggggat cgccgcgtgt
     4441 ctgacgctgc tgcgggcggc gccctcaccg cgccaccgtg cgccgttcga cctcccgggc
     4501 caggtgacgg cggtactcgc gctggccggc ctgaccttcg ccgtgatcga gggcggtcac
     4561 cgcggattga cgggaacggt gctgacggcg gtcggggtcg cggtggcgtc cggggtcggg
     4621 ttcgtggtcg tcgaggcgcg gcggcgcacg ccgatgctgc cgccgaagct gttccgacag
     4681 cgcggcgtca ccgtgccggt cgtcgcgggc ttcgccgtca acgcggcctt ctacggcggg
     4741 gtgttcgtac tgagcctctt cttccagcag cagcggggac agtcggcgtt ctcggccggg
     4801 ttgatgttcg tgccgatggc ggcgatcacc gcggttttca actacctctc gccgcgggcg
     4861 gtttcccgtt acggcccgcg ggccgtcatc gtcgtggggc tgctgaccgt ggcgctgggc
     4921 tgcggcgcgt tgctcgccgt cgacaagggc acgcccgcct ggctgaccgc gttgtcgatg
     4981 accccgctgg gcttcggcgg cgcgctggcc atgccggcga tgacctccct gctgctcgac
     5041 agcgtcgccg ccgcgcgggt gggcacggcg gcagcgctgc tcaacaccag tcgccagacg
     5101 ggcggagcgc tcagcatcgc cgtcttcggt gccctcatcg cccaggactt cgcgacgggt
     5161 atgcgccaaa gcctgctgct cgccgcctgc ctgttggtgg ccacggcgtt gggcgcaacg
     5221 gcactgctgc cacggcggtg agggcgaccg ggggactggc acccccgccg accaggtaga
     5281 tttccccagc agaccacggc tgacgcaacg agagcggagt ggagagtgga cgcacggtcg
     5341 ctgcccaacc tcgcgtccct acggtccctc gaagccgccg cgcggctgcg cagctacacc
     5401 ctggccgccc gcgaactgca cgtcacgcac agcgcggtca gccatcagat ccgccagctc
     5461 gaagcgcagc tcggggtggc cctcttcgcc cggtccggga cgcagatgct gccgaccccg
     5521 gtctgcgcac gcctcgcggc ccggctgcgc cgcagtctcg gggacctcgt ggaggccctg
     5581 ggggaggcca tgggcgaggc cggcgcgtcg tccatgccgt tggaactgag cgtgatggcc
     5641 gacttcgcca atgtgtggct catcccgcgc ctggcggacc tggcccgggc gcacccgcag
     5701 atcgagttgt cggtgcggct ccacacgggg atggccccgc ccgatccccg ctcggtggac
     5761 ctgggcatct ggcaccgtcc ggtcgaggct cacgaccacc gctccgtgcg cctgttggag
     5821 gaccaggtca tcgccgtctg cagtcccggg ctgacggccc gacacccggg gctgaccctc
     5881 gggacgctgc cccaggcacc gctgctccgc ttcgccctgc gctcctggaa ggagttcttc
     5941 gccgcggccg ggatcgacgc gggcgaaccc gcgcacgggg tgatctactc cgatgcggag
     6001 gcgctgctgc gggcggcgct ggccgggcag ggcgtggcca tggtgcgccg gcagatggcc
     6061 gacgcttacc tgggccgcgg ggacctggtg aggatcgggg acgtcgagat ccgcgaccaa
     6121 ctcgactact tcctcagctg gcgcgagggc catccgcgcg catccaccat ccacacgttc
     6181 cacgactggc tacggcagca gctcaccgcg gcaccggaac ccctcgggac aggcgacgat
     6241 ggtcgtagaa cgtgacgtcc tcgccctcgc gcagatccag cacctcgcaa ccggagtcgg
     6301 tgacggccgc acatccgctg tgtgtcaccg caccagccgt tcttcttgat gctcacatcg
     6361 acgccgaaga gatctccctt cctcagggga attccgttcg gctcgccact gaatgcgacc
     6421 tcattgtgtg cgatggatat ggcggcgtat gcgctggagt cgtagccgga caggtcttcg
     6481 cgatcgatct ccgcgccgta cttgtcgacg atgaggtcat gggcgatgtc attgatgcgc
     6541 cgggaggtgg ctcccggctt gatgtacggc gttggtgagg ggaattcaac gggcgtagag
     6601 ggcgcgccgc gccgtgcact ccgcgtcccg atcacccgcg ccgtgcgaac tcccggcccg
     6661 ggacgcggcg gcaccacggg tgagcgcggg ctccggaagg ggcagtaagt cctcaggcgg
     6721 agcaggtgag tgcgtcgggg atcttggcga aggtctcctc gaccagtttc gtcaggccgt
     6781 cgcggcctcc ccggccgccc tgtgccgtcc agtgcaggga agccgtgtgc caggcggcca
     6841 cgaagatctc cacggtcagg cggaggcgca ccccgtcgac gtcggcaccg gaacgctcgg
     6901 tgaccgtccg gacgatggcg ccagtggtgt cgtggcagta ccccaggctg tgtgcctgca
     6961 gtgcgggaac gccgtccgac agctcacggg tggccaggaa gcggcggtcc cagtccgggt
     7021 ccatcgcgcc cagggtggtg tccagggccg tgcggagaac cgccagcagc gggccgtcca
     7081 acttcagggc ggccacgtgg tccagatagg tcgaccacag gtcgctgtcg gaggcgagcg
     7141 cgacgtcctc cttggaccgg tagttccgga agaaggtgcg cttggacacc tccaccgcgt
     7201 cgcacaggtc gtcgagcgtg gtggcgtcgt atccgcgctc ggtgaacagg cgcagcgcgg
     7261 tctcggcgag ggttcggcga gtgcgcagct tcttgcgttc gcgcagcggc agggcgcgca
     7321 ggtcatcact cacacccagg agattaccac caggaagctt ttgccctttg acagctaatg
     7381 ccactcagtg gcactgtccc ctgagtggcc gactgtggcc gttgaacgtc ccctgaagga
     7441 gtctcaactc gtgactaccg tccctacggg ccgctcccgt ccgacgattg ccctgctggt
     7501 ggtgctgctg gccttcgtca ccgtgccgat gtccatctcc ggggcagccg tcgccctgcc
     7561 cgacatcggc gaggacctgc acgccgctgg cgcatccctg cagtgggtca tgaacgccta
     7621 caacctcacc ttcgcctcgt tcatgctcgt cgccggatcc acggccgacc tggtggggcg
     7681 tcgtcggacc ttcgcgaccg gtgcgaccgt gttcgccatc ggctcgctcg tcgcggcagt
     7741 cgcacccggc atcgtcctgt tggacatcgc ccgtgccctg tcgggcatcg gtgcggcggg
     7801 ggtgttcgcc agcggaggcg cgatcctggc cacgacgttc gacggcgccg cgcgcacccg
     7861 ggcgttcgcg gcgctcggca gtgccgccgg cctcggtctg gcggccgggc cgaccctggc
     7921 gggctggttg gtcggcgcac tcggttggcg cgccaccttc ggactgcacg cggtgttggt
     7981 ggtcgtggca ctggccggtg tcggtttcgt cgccgagtcc cgcgccgaac agcgaccccg
     8041 gctggatgtg accggtgccg tggtgttcgt cgccggcctg ggcctgctcg tcctgggtgc
     8101 ggtccagggc ccggagtggg gttgggcgag ccctggtgtg ctggcattgc tcgtcgtcgg
     8161 cgtggggctg ctggtgctct tcgtcgtcct gcaggcgcgc tcgacggcgc cggtcctgga
     8221 tctgacgctg gtgaagaacc gccggttctt ggcgttgtgc atggtgccgg tggtgtcgac
     8281 cttcggcttc gtgacgctgc tgacgtacct gcccacctat ctggtgggcg cgagcggctt
     8341 ctcgccccag cgcgcgggaa cggtgttgct gctgatgacc gcgccggtac tcctggcccc
     8401 accgctggcc ggggggctcg tcaaccgggg tgtgtcgccc cgtacgctca tcacgctctc
     8461 gttggtgatg ttcgccggcg gaaacgcctg gctcagcgtg atcgggcctt cctcctccgt
     8521 cgcggtgatc gccggtccgc tgctgacgag cggactggga gccggactgt cgttcggtgt
     8581 gggcgacggc gcggcgatga gcctcgtcga gcccgagcgg gccggcatgg ccaccggatt
     8641 cctcaacacc ctgcggatcg gcagcgaagc catcgtcatc gccgtgtacg gcgcggtgct
     8701 ggtcagcctc atcggcaccc gcgtcggctc gcaggaactg gccgcgcggg tcgccgcggg
     8761 cgacctgtcc ggcagcgacc ccggtgtgct ggcggacggg ttcacccatg ccctgcacat
     8821 cgcgctgtac ggaacggccg ccgtctgcgc gatcggcgcg gtggtcatcg ccgccgcact
     8881 ggccccaccg cgccgagccg ccgccgcggc gccctccgtc ccccaggacg cccaactgac
     8941 cacgaaggca ggctgatccg gcgccgccgg cggaccccgt ccggaacgaa agcgtcaatc
     9001 cccacgatca cgaccggatc gtggggatcg acgtcatacg aggggccgaa cagaccaacg
     9061 gcatccgtca gaggtgcggc cccggcacct cacacgcggt cagcggcgat cagcaggtac
     9121 tggaagctcc cgttgcggta ggcgttcaag aacgtgtcct cgatgccggt gaccaggtgg
     9181 tcggccttcc ggcgcagctc ccagtacggc agcgcggtct ccgtcaggtc ctcgacgtgc
     9241 acggggacga gtcggttgcg ggccatggcg ttgaagtacg ccgaacgggg gtggatgtcg
     9301 cagatgtagt gggcgttgat gagggacacc tcgcgggagg cgcggccgta ggcgtcgttg
     9361 tagcagccgg tgatcgtgac gtagcgcccg ccccgccgca gcagccgcgc gtgctccgcg
     9421 aacagcaggt ccagttcgac gtacatcgtc gactcgttgt tccaggacgc cgcgtacgca
     9481 ccggaggtga agccggtgtc gagcatgttg ccgtggtggt agcggacctt gtcgtcgata
     9541 ccccgtttgc gggcctgctc gttggcgaat tcggcctgct tggcggagat ggtggccccg
     9601 tcggcgtggc agccgtagcg caggttcgcc accacgctgc cgccgccgcg tccgcagccg
     9661 gcgtcgaaga cgcggtcgga cggggtgagg tcaccgaggt gggaggcgag cagctcggcc
     9721 tgggcgtgct ccaggcggtg cagttcgccg gtgacccgtt cccgacggcg gtcgggatcc
     9781 ggctcgtcca gcaccgacca gtcggcgtcc ccgatgccgt agtggtggtg gtacaggtcg
     9841 tcgatctttc cgagttcgag gttgaccggg ttctcctcgg cgttccagta gtccgcgacc
     9901 cgtgactggt acgtggactg ggtcggcacc ggcgtgcggg cggcggtgtc ggcgtgtgtg
     9961 atggtcaacg gtgactcctt gggacgatgc gtgcgcgggt ctaccagtag ttgggcagct
    10021 ggtagcggtc ggtgttggtg gcgtgccact cgtggttgcc ggagacccag tcggtcagcc
    10081 cccggacgta cttttcgagg aggggcgaga gggcggccag cggggccgac tccgcctcga
    10141 acgcctcgta gacctcgttg tggatctcga cgctcttcag gtaggcggcc ttcaggccgc
    10201 gtttgtcgtt ggcggccacc acctgcggca ggttgaggtg ggtcgggtca ctggccagtt
    10261 ccttggtgaa ggagtacagg tcgttgacga tggtcgtggc gttgcacgcc agcgcggtga
    10321 cccgctggac ctcgggacgg gcgtagagcg cctcgggcag ctcgtagccg tccacggtgt
    10381 ccacgaggga cagacagggg cggaagttgt tgaactgccg catgaccagg tactcccaga
    10441 cctgcggtgc gtgtcgcgtc tcggcccagg acgcctcggc gagatagccg aggtgcagcc
    10501 gtgccatgtc gtggacgaaa cggtccgcct ggctgggcgt cgagacggcc gcgaggtcct
    10561 tcatcgccca gtagtacgag cgcagcggtc cgtcggcctg catgccctcg tgccactcct
    10621 cctccagggc cggggtgccg tggaaggggt cgagggccga ctgggccagg atcagccggc
    10681 cggcgaggcc gctgcgcgac gcaccccgac cctcgtcctc ctcgcagtag caactgtcga
    10741 cgacgttctc cgccagcagg aacttccccg cgacggtgag gcgttcgaga tcgaccgcgc
    10801 cggggtgctg caggacgacg gcccggccgc actggaactc cgcgaagtcc ccggtccact
    10861 gcgcggggaa gaggtccagg ccgcgggccc actcctccaa cctgcggtcg atctccttgg
    10921 ccttctccgg gtcggcgggg acggccggcc ggtacttcag gccggggacg gctccgccgt
    10981 tgcgggcccg caggtcccgg acgaggttcg gcggtccggg catggtgaac ccggagtcgg
    11041 tgctgggggg cgtgctcatg gttggtactc caccgggtca gtcggcgctc cggccgagct
    11101 ggacgttctc caggatgccg acggcgtcgg gcacgaggat ggcctgcgag tagtaggcgg
    11161 tgacgaggta cttgatgatg gcggcctggt cgatgcccat gaagcggacg ttcagacccg
    11221 gttggaactc ctcggggatg cctgtctggt acaggccgac cacgccctgg tccgcctccc
    11281 cggtccgcag cgcgacgatg ctgctggtgt gcgtaccgct gatcgggatc ttgccgcacg
    11341 ggaagatcgg gacgccgcgc caggcaggga cctcgtgccc gtcgacgtcg gccgtgcccg
    11401 gcaccagacc gcgcttgttg cactgccgga agaaggcggc gatcgccttc ggatgggcca
    11461 ggaacaggcg tgtcttgcgg cgcatggaca acagctcgtc catgtcgtcg ggggtcggcg
    11521 gaccggtgta ggtgctgatg cgctggccgt agtcggcgtt gtgcagcagc ccgaactccc
    11581 ggttgttgac cagctcccac tcctggcgct cgcggatctc ctccacggtg agccggagtt
    11641 gctgctgggt ctggtccatg ggttcgttgt agaggtcggc gacccggctg tggacccgga
    11701 gcacggtctg ggtcagggag agttcgtact cgcgcggggc gagttcgtag tcgacgaagc
    11761 cgccggacag catcggctcg ccgacatgcc ccgcctgtac cggcacatcc gcttcgccct
    11821 tgcggttcat ggggagccgc tgctgctccg cgtacgccga caggtgcgcg gccaggctcg
    11881 gcacgcggcc ggtgaactcc tcgaccacgt cccagggcag caccatcacc acgccctcgg
    11941 tatccgcccg gacggagctc agccaccgcg gttcgggctg gccgatcgcc tcgtccccca
    12001 tctggtcgcc gtccgtgacg acaccgatga tctcctcctc gccgtacttg cctggcttgt
    12061 agcgggagaa ccggccgtgg acgacgagga acgcctcggt ggcgggctgc cccgcttcga
    12121 agaggacctg gccggcccgg acctcccgga cgcggaagcg gccggcgatc tccttgagga
    12181 cctcgatgtc gtcgtagccg cgcaggaccg ggagttcggt gagggtctgg gggatcacct
    12241 tgatgtcgtc cgcgccgttc tgctcgaact ggacacgtcc ccggccgact cggagctgca
    12301 gccgtcggtt gacccggtag gtaccaccct tgacgtccac ccacggcagc atcttcagca
    12361 gccaccgcga cgtgatggcc tgcatctggg gcacggtctt ggtggtggtg gccagttggc
    12421 gtgcggcctg cgtgctgagg ctggtgcgtg cgctgtctgc ggctggatcg agtacgggct
    12481 catcggtgac ggaaccggtg acgctgtccg gtgtggacac attccctccc gggacgtgaa
    12541 cagaggtgag cggaacggcc gttgatgggc agggggccgt gcgcagggac aagcgaaaca
    12601 ggctggagat catctcgata cggcgcgaag gagggcgcct tcgcactcag ggggcgcaaa
    12661 catcaagatg gcgtacgcgg atcaagatca cgattccgcg cgcccctggg ttaccacgct
    12721 tcccggagaa gcatgcgtcg cgaccagcgc caatcgtgtc gctcgttggt gatcgccttc
    12781 gcacaatgat gcgagacggg ccgaaaggcc cggagtcccc tgacactacc tggcgtcact
    12841 ggccggacgt cccgacgccc cgtgccgttc acgtcgaccc caatcacccc tcgggaggcc
    12901 cgagttccta cttggtggtc ttcgacgtgg ccgccttcgt gatgtcctga agcgtggtgg
    12961 agagactgcg catccccttg gcgatctcgt tcagggaggt ggtgaagagt gccccgcgtt
    13021 gttcttcggc cttgcgggtc tcgcccgtgg gcggaaccgt cgcctgctgg cacttctggg
    13081 ccccccgccg cagttggccg agcgtgtcgg accacgacgt ctgcaggtcc gggtcgggaa
    13141 cccggaagta gccctgtgcc tcctcgaccc gcttgcccag cgtgccgcaa gggccgtgga
    13201 accgcttctc gtccacccag acctgcccgt tcttgtccct gctctgggcg gagagcagca
    13261 ggatccggtg ggccagggct gcccaggcgg tctcgatctg ctgcgcgtgc agcgccccgc
    13321 cgtggtacat ccacgaccag acctgccatg tgtggagctt ggccgcctgg cccggagaga
    13381 gccggtccgg cttcttgtcg cccgtggccg ccgtgtcccc cgaggagccg gccacgacgg
    13441 acgagggcga ggaggtcgtc tgcaggatcg tcacgacggt cagcaacagg gcgggaacac
    13501 cgagcgcaag gaccgtgccc gtggtgagga gtgcccagcg ccgccggcgg ggcgcggtgg
    13561 gcgccgggac cgcgggcagg tccgacgtcg ccggccgcct gcgcagtcgg cgggcggccc
    13621 aggccgcgcc cgcgcccatc agggccgcgc aggccgcgcc gacgacggcg ccggtcagcg
    13681 tgaggtgggt gacccccttg tcgacggtca ggccgttgtg cgggcgccac tggcaggcgt
    13741 ccaggacggt gttcagcggt ccgaggcagc cgtcggcgga gtagagcacg aacaccccgg
    13801 catacgccat cagttgggtg atctgtgcgg cgatgagtgc ccgcagcagc cagtggtgtc
    13861 gggagtacgc cgccaccagt gcggcggtca gcccgcaggc cgccaacacc gtcacgatca
    13921 tccaccacgc gtgcacgacg aggaagggtc ccgcgcgctc cttcagcgtg gccggccgct
    13981 gcaggtacat cgcgtacatc gccgcggcca gtccggccca cgacaccagc ccgccggcca
    14041 cgcccgcgcc gagcgtccgg cgcatccgca gtcccggccc ccgcacaagc aggagaacca
    14101 gtggaacgaa ccacatcagg taggccgtgg catcggccag gcgctcctcg gacagcggcg
    14161 tgagaagcgg catgccgacc gtgagggtgg acagatccag gccgtagtcc cgccagttgc
    14221 ccggcaccat ccgggcgtac atcgcggcca acccctcgcc ggcatcgccg taccccatgg
    14281 cgatccgctc gcctcccagg cgccaccaca gcagtccggt gagcagcacc gccgcggtca
    14341 ccagcgcgca gaccacggct gccgcccacc gctgcccccg ccgcggcagg ccgagggcca
    14401 actgcaggct gtgggaccac cacagtgccg gcaccgcccc gatgaacagg aacgcgagca
    14461 ggtactcggg ctgcgacacc agcacgtcga gccggtactg gccactggcc gtcacctcgc
    14521 ccaccaacag gccgcagccc aaccagaggc ccgatgccac agcggacctg acgtaacccc
    14581 gcgccgggtc cgaggcacgc accagcggca ggcccaggcc ggcacagagc accggcgtca
    14641 ccaccgcgac cgtggccacc agggcgtacg accaccccac ggtttccggg agcagagcgg
    14701 aagacgtcaa ccccagcgct gagtacagga gcgacgccga ggcgccggtc aggaacatct
    14761 ccaacggact gacccggaaa ccacggccgg catcggcaag gacgccacga cgctccgccc
    14821 aactggggtg ggtccgcagc agcgtggtga gccggcgcag cgcgggggcc acggcacccg
    14881 ccgggtcgga ccggtcccaa ctgccgggat gcgcgcccca ggcaaccgcc tggaggtcgg
    14941 cgtggagttc gcgtcggcgc agcagatcgg cccgggcgag gtgcagcagc gcggtcagca
    15001 gcagcccgac gaagacctcg gccaacagcg tgggcgcggc cccgggccac catggcgagt
    15061 cggtgccgga gaacgcgagg aggaagatcc agccgatccc cgcgaagtgc ggcaggaggg
    15121 cgagcaggac gtagacccgc cacagtgcgg tactggcgta ggcgtagtcc acatcccggt
    15181 ggtggacgtg ggcgagctcg tgcagcacga ccgcacggaa gccctcgggg tcggtgccgc
    15241 gccgggcgag cagaccgaca tgcaggcaca cggtgtagtt cccggtgcgg ccgtaggcgc
    15301 tggcgcccga ggtcatccgg gccggatcga cgcggaagcg caggctcgac cggacgccgg
    15361 tgcgctcgca cagggcggcc agttcggctc gcagtgtgcc gtcggcatca acggcttcga
    15421 ccggcaccat cctgcgccgc cagtcgcgtg ctttcggcat ccaccagtag accagtgccg
    15481 cgaccgcgag cagcaccgcg gtcgcgatca acgcccggta gccgaccggc cggtcgccca
    15541 ggcacttcag cagggcgtcc ggacggctca tggtcgcccg gagattgccc agatcgctgc
    15601 tggaggggtc gaacccggcg gcgtacagac agctcggtgt gccgtacagg cccgcgccgg
    15661 ggcgccccga ctcggacagc accgagagct ggtcgagcac gctggtcagc gtcgcgaagc
    15721 tcgacgccgt cacgaggatg atcaggagcg cgaaccgggg tccggtgccg ctggaattcc
    15781 tgagcgccgc gaaagccctc gcgaggcggc cccgggtgtt cccggcgccc gtcgccccgt
    15841 gtaccggatc gcgtacgtat gccatcagca acccccgtac gtagcagtca agttgagcgt
    15901 aggttcggcg ccttcggagg agaagaggag cgacaccggg tacgggcgga aatcccgatc
    15961 ccgccggctc gtcggctcgc cggcccccgc ctacctgaag agaccttcag gtggcttcag
    16021 ctccgcttca ggtccgttcg accactgtgg tggcacagcg ttcgacagcg cgaacccgga
    16081 cgaccgggcc cgagcaacca cgtgaggaga gcacatgaaa cgccacctcg tcatcgccgc
    16141 cgccgcggcc gccgtgctgg cggtcggtac ggtcaccgcc gtcgcggtca gtggcagcgg
    16201 agccggcggc agcgcaccga ccgcggcgcc ggccgccggg aacggccgac aggacaccga
    16261 ggacctccgg gaggcccgcg ccgcccgggt gaccgcaccc caggcggcag ccgccgccct
    16321 caaggccgtc cctggcaagg tgtccggcct ggacctggac caggaccgcc ccggcctggt
    16381 ctgggacgtg gacgtgttgg gcaaggacgg caggtggcac gagatcaccc tcgacgcgcg
    16441 caccgcacga gtgctggagc agcgcatcga cggggggaat gacgacgatc acggtcagga
    16501 gcgagccgcc ctggacaccg cgcgggccga cgccgccggc gttgccagga cggccgccgc
    16561 cggacacggc acggtgacct ccgtcgaact ggacgatgac caccgtgcgc aggcggtctg
    16621 ggaggtcgag accatcaccg aggacggcat ggagcacaag ctcctcgtgg acccgcgcac
    16681 cggcgccctg cgcaccgccc cgacccatga cgcgtacgac gacaacgagg gtggcgacga
    16741 ctgagtcggt cggtcgtcgg ggctgccaca tggcgattcc gctgccgccg gtggccggcc
    16801 tgtacagccc tcagggcacg gtccggaagg ccgagttcag ccccgacggc cgcaccccgg
    16861 cccccatcgg cgaagacgcc accggccgcc cagcagcacc gcgcaggcca gcacggtcag
    16921 cagcccgccg gcgaggaacg tgccccgcac gccggcgagc ggaaggacca gcccaccgag
    16981 cgcggcgccc gccgcgatac cggcgttgta cgaaccggag ttcgccgcga gcgcgatgtc
    17041 cgtgcgtccg ggcgcgcaat gcagcatcgc gttctgagcg gtcatgaaca ccggcccgag
    17101 cgcaccgccc gtcaggacca ggaacaccac ggccgccacc tgatgggtgc cggccgcgaa
    17161 cagaccgagc atgcccaccg cctgggtggc cacggccgtg accggcgccg cgtgagggaa
    17221 gcggtccagc agcgccccgg tgatgccgac cccggccaga cacgccacac cgaagaccac
    17281 gagccagacg ccgaccgtgt tcggggcgaa gccgctcacg tcgagaagga acgtcacgat
    17341 gtaggtgtat cccgcgaacg cccccgtggc ggacagcgcg ccggccgcca gtacggtccc
    17401 gaaccgccgg gtgtcgggac tggttccgta ggcggcgggt tccgcctccg gcggtgaggt
    17461 cggcagcacg gcggcgatcg tgacgagcga gcagagcccc ggtcctgcga gcagcgcgac
    17521 gggcacctgc cagtcgctgt gctggcccag ccaggtcccg aggggaacac cgagaacgag
    17581 ggcgagcgaa ccggcgacgg acagcgcccc gaccacacgc ccacggacct cgggcgcgaa
    17641 caggcccacc gcgaccggcc ccgtcacggc ccagaacagt gcctgggcga gagccgtcag
    17701 cagccgtgcc acgaggagca gccagtagga ggtcgcctgc gccgcgacca gactggacac
    17761 gacgagcgcg gccagcagtc cggtgagcac atggcgcctg ggcacggtcc gcgtggcgtg
    17821 ggcgagcggc aaggacgccg cggccaccgt caccccatag ccggtgacca ggaggccgac
    17881 cgccgccacc ggaacccgga ggcttttcga gatgagctcc aggaggccga tcggcaggtt
    17941 ctccgccgtg ttgaaggtga acgcggccag catcagggcc gcgagaaccg tcgccgcgcg
    18001 ccatggagcc gggtgcgtgg cgcccctacg actgccttcc acccgcacgc cttgcgcccg
    18061 ttccatggca ccgtccatgg acgtacctca ccgagcccac ccgccccgcc gcaaccgaat
    18121 tcgctcttcg tccgatgccg gttcggccga ggggcgggcg gcagcgtcgc cagtcaccag
    18181 gccgtgaagt aagtcaccaa atgcgcgaga accggacttt tcgctcggtc gtctctccca
    18241 tcgatatccg ttggccaacc cgctggacag aaaaccgaag gagagcccct gtgtcctttc
    18301 ccctcgccct gagcaccggt gtcctcggct gtggtgtcat cgccgtggtg acgttcctga
    18361 tcggccgtcc ccggcggacg tcccatcgcg tgtgcagcgc gctgggatgg ttgtgggtgg
    18421 ccggggtcgt gggcctgacg ttcggcacgc gctccggagg cggacaggcg atgaacctca
    18481 agctgctcga cctctcgaac cccgccgaca cctgggactt cttcctcaac gtgctcatgt
    18541 tcgtccccgg cgggctgctc ctggcgagcg caggcgtgag tcttctgacc gcgacgaccg
    18601 tgggattcct gggttccctc gccatcgaga cgacgcagta cctcaccgcc tcggggcgga
    18661 cggccgacgt caacgacctg ttggccaaca cgctgggctg cgtcgccgga tacgcctgcg
    18721 ccgcagccgt ccgggccgcg ttccgcagga ccacggcgac cgccggaccg cgcctgcggg
    18781 cctgacgccg gaccgcgcgg ccgggcgtgc ggtccggagc cgatcacagg agttccggtg
    18841 ggacggccat gcggagggcg gcggtgacgg tggtgacggc cgggtggtcg gccgcgcccg
    18901 cgcggtggac cgtacgcgtg cgtcgggaca tcgggagtcg cgtgaggctc aagcccgggg
    18961 gtggtgcggt ggcgccgagg tgggggatca gggcgacgcc ctggccgagc gcgaccaggg
    19021 ccaggacggt ggcgaagtcg tcgacctcgt ggcgcacgtg cggggcgaag ccggctgcct
    19081 ggcaggcccg catggccatc gtgcggcaga gtctgccggg cggggccatg atccacgggc
    19141 tggtgctgtg gtcgttcaac gaactgggcg tccgggccgc caggtacatc ggttcggtga
    19201 acagttcctc gccggtcagg ccgggctgcg gctcggcggg gacgacgtcg tattcgtgca
    19261 ccagggccag gtcgagttct ccggcgcgca gcgccgcggc cacgccgacc ggatcgacgt
    19321 cgaggactct cgcctccagc atcgggtgtt cgcgggccag cgcggccagg gcggccggga
    19381 tgatcgcacg ggtcgcggac gggtagcttc cgatgcgcac cggtccggcc aacccggagc
    19441 gtacggctgc gagttcggct tctgcgtgtt ccaggcgttc gagtatgtcc tcggcgtgtc
    19501 ggaccaggtt ctgtccggtc ggggtgagtg cgacccggcg ccccgtccgc ttgagcaagg
    19561 gcactcctgt ctcgcgttcc agcagggaca gttgttggga gaccgcggat gggctgaacg
    19621 acagtgcctc ggcgacggcg gcgatggtgc cccggtgtgc gagttccctg agcagacgca
    19681 ggcgacgaac atctagcatc agctcagctt acgagcacca tcgagagtgt gaactggacc
    19741 tgtgcgacaa cgggtcgcca tgctcaaggg tatggaactg catggcattt acgtaccgtt
    19801 ggtgacgccg ttcgcgcagg acggggaggt cgcgttgggg gcgttggagt cactggcgcg
    19861 ctcggtgctg gcggagggtg cggctgggtt ggttgcactg gggacgacgg gggagcctgc
    19921 cacgctttcg ccggaggaga ggcggcaggt ggtggaggtc tgcgcccggg tgtgccggga
    19981 gcgcggggcg aggctgatcg tgggcgccgg cggcagcgac accggacgga gcgcgctggc
    20041 gctggaggat ctggcgcagg tcgcggacgc cgcgctggtc ccggtaccgc cgttcgtccg
    20101 gccctcgccc ggcggggtgc tcgcgcactt cgcacacctg acggagcaca gcccggtacc
    20161 gctggtggtc tatcacatcc cctatcggac cgggcaggca ctgggcgccg gcacgctgcg
    20221 tcgactgtgc cggatgcctg ggatcgtcgg ggtcaagctg gcgaccggct cggtggacga
    20281 ggacaccatc gagctgatgg gcgacctgcc acccgacttc gccgtgctgg ccggggaaga
    20341 cgccttcctg gccccgctgc tcgcccttgg ggccacgggc gggattcttg cttcggctca
    20401 cctggccacc gcgcatttcg tcgaactgct caatgactgg gacaagggga atctggtgca
    20461 cgctcgtgca cttggtcacc gtctggcggc gctggcccgg gcggtcttcg ccgagcccaa
    20521 tccggcggtc gtgaaggcgg tgctggcggc tgagggtcgg attccgacgc cggcggtacg
    20581 gctgccgttg ctgcccgcga gccagaccgc agcagcacgg gcgtcggcct gcctcgatgc
    20641 gctttccgag gggccctgaa cggccccgcc cggggcgtcg gccacggagc ggagagcgat
    20701 ccgatcctcg ggtccatagg ggtggattcg cccagacaca cgcgtcaccg ggggccagag
    20761 gcggcagcgt tacacaacac ccagtcgccc gtcctaggag gaacgccatg caccgtggga
    20821 ctcgtcgaat cgtcgccgtc gtcatcgggg ctgtcgcact cgtcggactc atgtcccccc
    20881 aagccagcgc cggcggaggc agcccggtca agagggcgat catgaagttg ggactgccgc
    20941 ccgacggcat cggcaccctc ctcatcgacg ccgccggcgc cgccgctgcg atcgtctagc
    21001 ggccgcgaag aggtgacact gccgtaggcg ggggccaggt cgtgtccgca gagtcccgc
//
