LOCUS       NZ_CP054019            20975 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. A1-5 chromosome.
ACCESSION   NZ_CP054019
VERSION     NZ_CP054019.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. A1-5
  ORGANISM  Streptomyces sp. A1-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9459690)
  AUTHORS   Dashti,Y., Sumang,F.A.M., de los Santos,E.L.C., Alcantara,E.P. and
            Challis,G.L.
  TITLE     Structural revision and biosynthesis of polyketides FXJ15321 and
            FXJ15322 from Streptomyces sp. A1-5
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9459690)
  AUTHORS   de los Santos,E.L.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2020) Warwick Integrative Synthetic Biology
            Centre, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL,
            United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUN-2019
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:28:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,328
            CDSs (total)                      :: 8,230
            Genes (coding)                    :: 7,847
            CDSs (with protein)               :: 7,847
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 383
            CDSs (without protein)            :: 383
            Pseudo Genes (ambiguous residues) :: 0 of 383
            Pseudo Genes (frameshifted)       :: 156 of 383
            Pseudo Genes (incomplete)         :: 280 of 383
            Pseudo Genes (internal stop)      :: 26 of 383
            Pseudo Genes (multiple problems)  :: 73 of 383
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:08:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8952499
            Orig. end                         :: 8973474
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Philippine National
            Collection of Microorganisms.
FEATURES             Location/Qualifiers
     region          1..20975
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="38"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20975
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20975
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10975](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10975)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(392..1129)
                     /locus_tag="HRD51_RS39270"
                     /old_locus_tag="HRD51_38760"
     CDS             complement(392..1129)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982648.1"
                     /locus_tag="HRD51_RS39270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38760"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_205367902.1"
                     /transl_table=11
                     /translation="MLTIGQLAATAGVTVRTVRHYHHVGLLPEPERDASGYRRYSAQAA
                     VDLIRIRTLADAGVPLARIDALLHAQPAEFDAAVTDIDAALQRKIDQLTEYRRRIAELA
                     AGERLFLPSEVVAILDRMRGYGVSELRVRLERDSWILMQALDPHTMPRRIREKNAAFDD
                     PETTRLYLACDEAVDWDPHDPRLERLIDDLDAWQITHERDSHRAGSRELVSSRISEASP
                     AWQRILDALAHRAERRRTAGHDS"
     gene            complement(1174..2085)
                     /locus_tag="HRD51_RS39275"
                     /old_locus_tag="HRD51_38765"
     CDS             complement(1174..2085)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (35-143). E-value:
                     8.2e-13. Score: 40.5. Matches aSDomain:
                     nrpspksdomains_HRD51_RS39275_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="HRD51_RS39275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38765"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_235095566.1"
                     /sec_met_domain="PF00561 (E-value: 4e-09, bitscore: 35.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-10, bitscore:
                     41.2, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.2e-07, bitscore:
                     30.2, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNNSTSSVRPAPPIGRFQEIDGRRVFVQRSGSGGPAVVFLPGAS
                     AVGLDYFGVQQQVSQFTTAVVYDRGGTGYSDPLPLPRTAAAVAAELHDLLHAEHIAGPY
                     VLVPHSLGGFYAHRFAQLYPQDVAGLVWLDAFHRDWDDFMPPAARLAAVEQMAPGREQL
                     EQLRPALREMFAELLADYPEHLRQALVDAKVSDAWTHIGIAERTKLAELATELRAGPNM
                     PDVPVIALTVVGTDPAQQVLTSERTLQEMHEGHTRMDAALVNAVSHGEQRIVSDTSHHR
                     LCFDRPDAVVQAIRDVVARARP"
     aSDomain        complement(1657..1980)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS39275_Abhydrolase_1.1"
                     /evalue="8.20E-13"
                     /label="HRD51_RS39275_Abhydrolase_1.1"
                     /locus_tag="HRD51_RS39275"
                     /protein_end="143"
                     /protein_start="35"
                     /score="40.5"
                     /tool="antismash"
                     /translation="PAVVFLPGASAVGLDYFGVQQQVSQFTTAVVYDRGGTGYSDPLPL
                     PRTAAAVAAELHDLLHAEHIAGPYVLVPHSLGGFYAHRFAQLYPQDVAGLVWLDAFHRD
                     WDDF"
     CDS_motif       complement(1723..1782)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS39275_0001"
                     /evalue="7.90E-05"
                     /label="NRPS-te1"
                     /locus_tag="HRD51_RS39275"
                     /protein_end="121"
                     /protein_start="101"
                     /score="15.2"
                     /tool="antismash"
                     /translation="GPYVLVPHSLGGFYAHRFAQ"
     gene            complement(2269..6561)
                     /locus_tag="HRD51_RS39280"
                     /old_locus_tag="HRD51_38770"
     CDS             complement(2269..6561)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538393.1"
                     /locus_tag="HRD51_RS39280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38770"
                     /product="bifunctional nitrate reductase/sulfite reductase
                     flavoprotein subunit alpha"
                     /protein_id="WP_235095567.1"
                     /transl_table=11
                     /translation="MASGSKDGSVRTVCSYCGVGCGIVLDVVRDPADGRRRVAKASGDR
                     AHPTNSGRLCTKGATSADMMAAPGRMTKALVRAERGAQPVETEVDDAIASVAGRLRAIL
                     DEHGPDALSFYVSGQMSLEAQYLANKLAKGFVRTNQIESNSRLCMASAGSGYKLSLGAD
                     GPPGSYQDFDRADVFFVIGANMADCHPILFLRMMDRVKAGARLIVVDPRRNATAEKADL
                     FLQIRPGTDLALLNGLLHLLVANGHTDEQFIAEFTEGWEEIPAFLADYPPERVAELTGL
                     AENDIRRAAQWIGEAGDWMSCWTMGLNQSTHGTWNTNALVNLHLATGAICRPGSGPFSL
                     TGQPNAMGGREMGYMGPGLPGQRSVLVDSERAFVERLWQIPEGSLRTDVGRGTVEMFQE
                     LAAGAIKACWIICTNPVASVANRKTVIAGLEAAELVITQDVFAETETNAYADVVLPATL
                     WAESDGVMVNSERNLTLVPGVVDPPGQALPDWQLIARVAREMGFGEGFGHASAEEVFEE
                     LKQAWNPTTGWDLRGVTYERLRTTPVQWPAPTTDGPDRNPIRYLNNGVSQTLVEREDGT
                     LPRLAFPTASGRARFYARPHLPAAELPDDDYPFMLTTGRLQHQWHTMTKTGKVAKLTKL
                     GSGPFVEVHPEDAGALGIAAGDHVEIASRRGRAVLPAVVTDRVRPGTCFAPFHWNDLFG
                     EYLSINAVTNDAIDPISFQPEFKVCAVTLTKTAAPVPRARPGTRPEATPAAAAHEDEPV
                     HPVPDQGGATARSNAAVHALAGMFGITDLTPAPLVEPERRYLSGYLAGLALNPPDGDVP
                     VLPSDAPLSPGSALWVGGALAGMFSRSAVPVAQAPATRESELGPARTTSSAADAAVPTR
                     RLVILWASQTGNAEEFATTAAAHLTAAGRTPELLPMTDMAPAQLVPDTDLLLITSTFGD
                     GDAPDNGADFWQALSAPTIGPLEGIRYAVLALGDSTYDDFCGHGRRLDERLDALGATRL
                     VGRTDCEPDFEETAEQWLGQVVTALATPDDSHSTAAGGLAAPAPGPAVTAAPTTTPTAA
                     TAPPAPEPVGYTKASPFSTLLIGNRLLSLPGSQKEVRRFAFDTRDHELAYAAGDALGVW
                     PVNGAGLVAEWLALTGADPDEPVELGDGARLPFEEALRTRLDITRITTDLLKFVVERTR
                     SQDLKRLLRPDNKDALARWSWGRQAADVIGAFPFRASAPEWSAVLKRLQPRLYSISSSP
                     LAHPSEVRLTVSVVRYTNDLGRDRKGTCSTYLADCADDGPVRVFVQRSPHFRPPADPAA
                     PMVMVGPGTGVAPFVGFLEDRRARGHTGPNWLFFGEQRQATDFYYREELAGFQASGHLD
                     RLDLAFSRDQRNKIYVQDRMHENGARLWQWLQDGAHFAVCGDAGRMAKDVDQALKEIAT
                     THGGMDADEATAYVRRLAADKRYVRDVY"
     gene            complement(6886..7234)
                     /locus_tag="HRD51_RS39285"
                     /old_locus_tag="HRD51_38775"
                     /pseudo=""
     CDS             complement(6886..7234)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016579353.1"
                     /locus_tag="HRD51_RS39285"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38775"
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHEYSGSVFLADCPARLAIDHRRQVGGGRVVRIESGTVPARRVGR
                     SDRRDLPEGADSDAAAVAGLRPRRPPCQGREGRVRADGLGPDPGAADRRADSVGPRARR
                     GRGGVPRVRDGL"
     misc_feature    complement(7040..7042)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7324..7641
                     /locus_tag="HRD51_RS39290"
     CDS             7324..7641
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013672.4"
                     /locus_tag="HRD51_RS39290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_235095568.1"
                     /transl_table=11
                     /translation="MSTEIDWPGGKKVAALVTVALELWSPGHGPAYAPMAAAWPLSGVD
                     DTHSTSWVDYGVTTGIWRLLDTLGDLPATVGVNGLVAERYPDTVAAVHQAGHEIAGHSW
                     T"
     gene            7667..8053
                     /locus_tag="HRD51_RS39295"
     CDS             7667..8053
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS39295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_235095569.1"
                     /transl_table=11
                     /translation="MDTERDNIRRCTDVIERVTGVRPTGWTSPRATGSKHTCDLLTQAG
                     YRWTGDHNDRDLPQVLPTAHGPLVSLMHSDHSDVRSAAAGPYAYRDLHRVLLDHLRAAP
                     GPGVFHLTVHAHVGHVLTYQGVTR"
     gene            8050..8535
                     /locus_tag="HRD51_RS39300"
                     /old_locus_tag="HRD51_38785"
     CDS             8050..8535
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017206.4"
                     /locus_tag="HRD51_RS39300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38785"
                     /product="NmrA family NAD(P)-binding protein"
                     /protein_id="WP_235095570.1"
                     /transl_table=11
                     /translation="MTHVLVVGGTGAMGSHVIQHLLATTGATITVPTRHPESAHATELA
                     ATAPHRLRLVRSDPAALDALMGQADRVFANTDFFATGSAVGEYRQGLELLTAAERPLPS
                     LRSRAPPAATSRCRTTNCTSPYLTSATTTQRCSGSSPTVISTAETGTSPFSDASTPT"
     gene            complement(8738..8929)
                     /locus_tag="HRD51_RS39305"
                     /old_locus_tag="HRD51_38790"
     CDS             complement(8738..8929)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS39305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_38790"
                     /product="hypothetical protein"
                     /protein_id="WP_235095571.1"
                     /transl_table=11
                     /translation="MRIARLWVECVQELGPGETADVRLAPLSPEQWRQLKPGDVMTMHE
                     GRPAVGTATVIEVRPPRA"
     gene            complement(9083..9766)
                     /locus_tag="HRD51_RS39310"
                     /old_locus_tag="HRD51_38795"
     CDS             complement(9083..9766)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017959.4"
                     /locus_tag="HRD51_RS39310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38795"
                     /product="DUF998 domain-containing protein"
                     /protein_id="WP_235095572.1"
                     /transl_table=11
                     /translation="MKSRIGYCAWIVGVGQFFTAHVVVESAWARPYSWARNNISDLGNA
                     LCALQPDPEPRYICSPEHGLMNASFIALGVLLVVGVALAGGVVWRRGPLAAGSRLLLAG
                     AGVGFVLVGLAPADVNESQHVLGALLIMGTGNIGLLLAAFSLTDRLAGPLRWGTGLLGG
                     AAIAAFGLFLTERYLGLGMGGMERVAVFPLLVWALTVGVHGLVRRPDRRPGAVSAPRLA
                     QPLRR"
     gene            complement(10001..10975)
                     /locus_tag="HRD51_RS39315"
                     /old_locus_tag="HRD51_38800"
     CDS             complement(10001..10975)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669514.1"
                     /locus_tag="HRD51_RS39315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38800"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_235095573.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-51, bitscore:
                     174.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATASRPTDPLIPLIEAELIRSVGSGEDLLETACLDALFPGGKL
                     LRPTLCVESARAVGGRAESVLSFAAAIECLHVASLVHDDIVDQDPVRRGRASTAERFGI
                     AEALLAGDGLFTAGWAAMLRGGPADRVLAASRAIAEAVHAMCRASMREIEIREDLTCGR
                     SAVLEVIRGKTAALTGAACRAGAILAGAAPEQIDALHHYGEQLGMAFQIRDDLLPYTAD
                     DALTGKSAVSDVANRQPTLPVLLAYESADAHDRRHLTEIFHGNVDLATAHRDLLDVLAR
                     TGAIAEAARQARACASQARAALGGLSATGRLARLADSAADRHQ"
     gene            complement(10993..11166)
                     /locus_tag="HRD51_RS39320"
                     /old_locus_tag="HRD51_38805"
     CDS             complement(10993..11166)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS39320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_38805"
                     /product="hypothetical protein"
                     /protein_id="WP_205367892.1"
                     /transl_table=11
                     /translation="MDDSPASAWTDAMGRHCTLLLGLVRAAGADLLHRPVRPPVSALFD
                     VWQRQWRTIIPC"
     misc_feature    11397..11411
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(11551..12366)
                     /locus_tag="HRD51_RS39325"
                     /old_locus_tag="HRD51_38810"
     CDS             complement(11551..12366)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046016.1"
                     /locus_tag="HRD51_RS39325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38810"
                     /product="ABC transporter permease"
                     /protein_id="WP_235095574.1"
                     /transl_table=11
                     /translation="MRRHLTFFVTAARYDLVMHARNRFAMFLVVLYVPAWVTLAHAALP
                     DKPAPVRLNSTGEFLSPPGDQLSQITGALNAVTLIAGFMMFAATFNGGRFDRRLAMAGH
                     PRIHLALAKTTSLALACAAVSVYATAVTCAAWIPRQPALLATALFCDAMTYGALGVLFG
                     CVLRREVEGMFAMVMTSIIDVALQNPIANTGANSPLVRLLPSYGSMQAATGAGFTNGTM
                     ASCLAVQTLWFAGAALLALLAFHRRTRSAFPRTRRPRTPTRRRPAHGTR"
     gene            complement(12363..12968)
                     /locus_tag="HRD51_RS39330"
                     /old_locus_tag="HRD51_38815"
     CDS             complement(12363..12968)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385751.1"
                     /locus_tag="HRD51_RS39330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38815"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_205367890.1"
                     /transl_table=11
                     /translation="MDVKGVHHAYGRRVVLRGIDISLRRGVVAGIVGENGAGKSTLLKI
                     LAGELRPQRGVVVHRGRFGYCPQDVVLNDALTVRQHLKFFMTAFGLSDLCRAEGLMEVL
                     RFSEYADERAGVLSGGTRQKLNLTLALMHDPQVLLLDEPYQGFDWDTYRRFWDLAAGLR
                     EAGRSVLVVSHLAYDTGRLDELWYLEGGVLRPRAEAAP"
     gene            complement(13210..13602)
                     /locus_tag="HRD51_RS39335"
                     /old_locus_tag="HRD51_38820"
     CDS             complement(13210..13602)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025887.4"
                     /locus_tag="HRD51_RS39335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38820"
                     /product="DUF4440 domain-containing protein"
                     /protein_id="WP_235095575.1"
                     /transl_table=11
                     /translation="MEPDRVTDERLHGVLAELMGREPLFHRPEFGMSRADFEAMTAPDF
                     WETGASGQRYSRAYVLDVLEERSQEPPVEEWETSDFHCRELAADLYLLTYTLVLNGRRT
                     RRSTIWQQASDGWRIVYHQGTPVQDA"
     misc_feature    13609..13625
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.98"
                     /tool="antismash"
     gene            complement(13944..14663)
                     /locus_tag="HRD51_RS39340"
                     /old_locus_tag="HRD51_38825"
     CDS             complement(13944..14663)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019846.4"
                     /locus_tag="HRD51_RS39340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38825"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_205367887.1"
                     /transl_table=11
                     /translation="MTPAQWEALLYDWHNAHRLRRQRNDTAYWARLTEQHDTVLVLGAG
                     TGRVASTLAHPARRRVTAVDLSRERLARMPRTPGLHPVCGDMRRLPLRGSHATAVIPYS
                     TLQLLVTPHDRQRALAETARVLAPGGSIHIDVSESFDARTETDWQIGLAEPCREAGGPV
                     EEWERHRLHADHVVIEKQFRRSGRVLTEVTERWAFHSALNLAEALAQAGFELVGIDRGY
                     GTDLSPHRLIYHGRRTH"
     misc_feature    15323..15336
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.36"
                     /tool="antismash"
     gene            15654..16892
                     /locus_tag="HRD51_RS39345"
                     /old_locus_tag="HRD51_38830"
     CDS             15654..16892
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="HRD51_RS39345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38830"
                     /product="MFS transporter"
                     /protein_id="WP_235095576.1"
                     /transl_table=11
                     /translation="MSTLQSQSTSALLLLLLSLLALRVTGSPASAPLVVAVGALPALLL
                     VRAVRIVNQRVDHRWVMLLSDTGAFAVAVTLWLLVRGGGVHAWQIYAGMFLFASFGAFY
                     LPAMRDWVAGQTTGLEQLTWLNAMLAVATQASVVVGWALGGVLASSIGIQASLGLCALS
                     YAVGLVLQFVVFVVINRAPLHKSPVAAGSAGPGAAEPDTSGEGRPSAAGVWREVFSPRR
                     LGLFTAALLLMELAHTLGFSMFVPLLTGGASDRSWIAGTANACFALAAMISGVLVSGGT
                     LGRWTRARVPQIVLVGFCVQVVFGLSAAHPVWAICLYAVVGLLSGGDAALQSEVQDRWR
                     PAGSAQAFAVFGAVQGPSQLVGSLLVAALLTCLSVGTVYLGTIVVLGLGSGLVLVLARS
                     RAAAASPRAEAPV"
     gene            16967..17776
                     /locus_tag="HRD51_RS39350"
                     /old_locus_tag="HRD51_38835"
     CDS             16967..17776
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015411.4"
                     /locus_tag="HRD51_RS39350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38835"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_235095577.1"
                     /transl_table=11
                     /translation="MANLALYGLGEMGADIARCLVARGVELHAYDPVADVAPEADHFHR
                     CATAAEAARAATVHLVVVKRPDDVRTLLFGADGLCAAAPPGSHVVLHTTLTPQTVRELA
                     DAVRQQGHVLLDAALSRRDGLVRDGSLSLFVGASAAELGTVRPVLERYADNVVHVGPTG
                     AGMTVKLCNNWLLYSNRHAALQALRTGRALGVDPDVLRGALAASTGSSWALAHYSDLDE
                     AIVTGQGAPAVVRDRTTSELHMAREMAATSGQVPTSLQETFALLDAM"
     gene            17831..18742
                     /locus_tag="HRD51_RS39355"
                     /old_locus_tag="HRD51_38840"
     CDS             17831..18742
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS39355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_38840"
                     /product="hypothetical protein"
                     /protein_id="WP_235095578.1"
                     /transl_table=11
                     /translation="MDSDTVSPDELAKVVAGLPVQVWNSPTAAELYGHTLNLVCRTRAG
                     RTAGVWVVPLDDGGTAARRPFRLLPYAAPWSDPGLHPVDRHRAVHSMTQALMARVDSAE
                     LPMDPRFGEVAALCEAGAELLCRHTRILELREGCDPRSAYVATARNHIRAAARRHTVHS
                     APLDSFDFSRAVVGQPAPAVAARRRSGLRIGREEPALCLAATDPDGVCRGQVFVLLCDG
                     AAVLMHSWFDRTGARGVPSLLVDEAITWAQRQPGTEVFDFEGSVLPSIDRFMTGFGAHA
                     RGYPQLRWIRSGRPGSDAGEFG"
     gene            18739..19857
                     /locus_tag="HRD51_RS39360"
                     /old_locus_tag="HRD51_38845"
     CDS             18739..19857
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024871.4"
                     /locus_tag="HRD51_RS39360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38845"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_235095579.1"
                     /transl_table=11
                     /translation="MTATGRPAEPDLDARRPTADPAAPHPLPGGRAVPEPEPAHDLRLV
                     DLDALPGAQEDAWARAYRRHGTRLQQSPGYAHAVRAAGHRVVVALAPDGIAAFTRDGDV
                     LTAVGDDEPLLTEHGHPERLARLVTSVRRATGASVYLPLVAAPHAEACARAGCTTWRRP
                     PNSLIDWSHDGADLWERALERGSSQLRRKRHLVERDGLTVRPGRSGPRAFADVLAVDDR
                     SWKAARGQSMRQRGGQDALYGRLVDTGEITAAFLLDGERPVAFRLDARVQDRLMSLKWS
                     YDETYRRYSPGLYLLTEGLRQEWAGRGVCTVDLHGSPDALKDLLHTERVPRADVWCGAA
                     GPGALRARERAALDARVAGAHEAGKGLRHAFD"
     gene            19844..20770
                     /locus_tag="HRD51_RS39365"
                     /old_locus_tag="HRD51_38850"
     CDS             19844..20770
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056: DegT/DnrJ/EryC1/StrS aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013227.4"
                     /locus_tag="HRD51_RS39365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_38850"
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="WP_235095580.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.9e-33,
                     bitscore: 114.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSTDPAVAAAVQDLLHRWGQPAAEFCASGGTALEAALEVLEVGA
                     GAEVVVPDVGCHSVAAAVVRSGAVPVFVGVGEDLTLHRDDVAAACSARTRAVIAVHQYG
                     LPCDVTGIARSLPPDVVVIEDVAQTWGSTTRGVPAGATGTLTVASFGPSKPVSLGAGGA
                     LLGPADLVSGAVARGDTTDRHRPRPPSPARFPAPLLPLLPDAIARADRQLARRRAVVDR
                     FRDSDLARHFRLPPLPPGSSAGWTRLPLYPAPSATARHIGQLADDLGSVQPMHPQPPSA
                     LPMFHRCEKRVLTGGRRPVEPLLVKIG"
     misc_feature    20777..20790
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
ORIGIN
        1 gcacgaaacc gaaggacgat cacaacctca cacagcccct aggccactcc cacagcacct
       61 tccaggccgt cggcggtgag gatccgaagc gacgacaacg gcagcgacca gcaccgtgga
      121 gaccactacc cggatcggta cttccggcac cgccgcgggc gcgagggcgg gggctgttcc
      181 gcgtgcgcga gggtgcgcag agacagggcg agagaggcgg ccgccacagg cgttcgcctt
      241 ccgccaccac ggtcgcgccg ccggctccgg catcgtgacg caactcccgc actgggcctg
      301 acgggcggag cggcagccgg atcgccgtag ccggcaaccg tgccgtgaaa cgcgacagcc
      361 cgctccgtgg gacgtggcca gggcgccggc gtcagctgtc gtgtccggcg gttcggcgcc
      421 gctcggcgcg gtgggcgagc gcatcgagga tgcgttgcca ggccggtgat gcctcggaga
      481 tccgggaaga gaccagctcc cgggaccctg cccggtggct gtctcgttcg tgtgtgatct
      541 gccaggcgtc caggtcgtcg atgagccgct ccaggcgtgg atcgtgcgga tcccagtcga
      601 ctgcctcatc acaggcgagg tacaggcgcg tcgtctcggg gtcgtcgaag gcggcgttct
      661 tctcccgtat ccgccgcggc atggtgtgcg ggtccagtgc ctgcatcagg atccacgagt
      721 cgcgctcaag ccgtaccctc agttcgctga ccccgtaacc gcgcatccgg tccaggatgg
      781 cgaccacctc ggagggcagg aaaagccttt cgccggcggc cagttcggcg atcctgcggc
      841 ggtactcggt gagctggtcg atcttgcgct gcaatgcggc gtcgatgtcg gtgacggccg
      901 cgtcgaattc ggccggctgg gcatgcagca gcgcgtcgat acgggccagc ggcacccccg
      961 catcggcgag ggtcctgatc cggatgagat cgaccgccgc ctgcgcgctg tagcggcggt
     1021 agccggaggc atcgcgctcg ggctcgggca acaggccgac gtggtggtag tggcgaacgg
     1081 tgcgcacggt cacgccggcg gttgccgcga gctggccgat cgtgagcacc gtcctcctcg
     1141 ggtcctcgtg gaacgtggtc cggtcgagtc taatcagggg cgggcccggg cgacgacgtc
     1201 gcggatcgcc tggaccacgg catcggggcg gtcgaagcag agccggtggt ggctggtgtc
     1261 ggagacgatg cgttgttccc cgtgcgagac cgcgttcacc agggccgcgt ccattctcgt
     1321 gtgaccctcg tgcatctcct gcagcgtccg ctccgacgtc agcacctgct gcgcggggtc
     1381 ggtgccgacc acggtgagcg caatcaccgg gacgtcgggc atgttcggcc cggcccgcag
     1441 ttcggtggcg agttcggcca gcttggtgcg ctcggcgatg ccgatgtggg tccaggcgtc
     1501 actcaccttg gcgtcgacca gcgcttgccg caggtgctcc gggtagtccg cgagcaactc
     1561 cgcgaacatc tcgcgcaggg ccggacgcag ctgttccaac tgctcccgac caggcgccat
     1621 ctgctcgacc gcggccagcc gcgccgcggg cggcatgaag tcgtcccagt cgcggtggaa
     1681 ggcgtccaac cagaccagcc cggccacgtc ctgcgggtac agctgcgcga accggtgcgc
     1741 gtagaaaccg ccgagggagt gcggcaccag cacgtaaggg ccggcgatgt gctcggcgtg
     1801 cagcaggtcg tgcagttccg cggcgaccgc ggcggcggtg cgcggcagcg ggaggggatc
     1861 gctgtagccc gtgccgccgc ggtcgtacac tacggcggtg gtgaactgcg aaacctgctg
     1921 ctggacaccg aaatagtcca ggccgaccgc gctggcgccg ggcaggaaca ccacggccgg
     1981 tccgccgctg cccgaccgct gcacgaagac gcggcggccg tcgatctcct ggaaccttcc
     2041 gatcggcggg gcgggccgaa ccgaggaagt gctgttgttc gtcatgcgac caggttccaa
     2101 ccctgacgca cggtcaaggt caactccttc tgctgcggtt gtcgcccatt gactgacgtc
     2161 ctttggctgc cgtcccctgg ctgttgtccg ccgactggcg tcccttggct ggtgtctctt
     2221 ggctgtcctc tcttggctgg tgtgcgtcgt gggtggacgc gcggtcgatc agtagacgtc
     2281 gcggacgtag cgtttgtcgg cggcgaggcg cctgacgtag gcggtggcct cgtcggcgtc
     2341 catgccgccg tgcgtggtgg cgatctcctt gagtgcctgg tccacgtcct tggccatgcg
     2401 gccggcgtcg ccacagacag cgaagtgggc gccgtcctgg agccactgcc acaggcgggc
     2461 accgttctcg tgcatccggt cctggacgta gatcttgttg cgctggtcgc gggagaaggc
     2521 gaggtcgagg cggtcgaggt ggccggatgc ctggaacccc gccagctcct cgcggtagta
     2581 gaagtcggtg gcctggcgct gttcgccgaa gaagagccag ttggggccgg tgtgaccgcg
     2641 ggcccggcgg tcttcgagga agccgacgaa gggggccacg ccggttcccg ggccgaccat
     2701 gaccatgggg gcggcggggt cggcgggcgg acggaaatgc ggtgagcgct gcacgaagac
     2761 ccgcaccggg ccgtcgtccg cacagtccgc cagataggtc gagcaggtgc ccttgcggtc
     2821 ccggccgagg tcgttggtgt agcggacgac ggagacggtg agccgcacct cgctggggtg
     2881 ggccagggga ctggaggaga tggagtacag gcggggttgc agacgcttga gcacggcgga
     2941 ccattccggg gcggacgcgc ggaaggggaa cgcgccgatg acatcggctg cctgacgacc
     3001 ccaactccac cttgccaggg cgtccttgtt gtcgggccgc agcagccgct tcaggtcctg
     3061 gctgcgggtg cgctccacca cgaacttgag caggtcggtg gtgatgcggg tgatgtccag
     3121 tcgggtgcgc agggcctcct cgaaggggag gcgcgcaccg tcgccgagct cgacgggctc
     3181 gtcggggtcc gctccggtca gggcgagcca ttcggcgacg aggccggcac cgttgaccgg
     3241 ccacacgccg agggcgtcac cggcggcgta ggcgagttcg tggtcacggg tgtcgaaggc
     3301 gaaccgccgt acctccttct gggaaccggg caggctcaac agccggttgc cgatgaggag
     3361 ggtgctgaac ggtgatgcct tggtgtagcc gacgggttcc ggagcgggcg gtgcggtggc
     3421 ggcggtgggt gtggtcgtgg gcgccgcggt gacggcaggg ccgggagcgg gcgccgcgag
     3481 cccgcccgcg gccgtggagt gactgtcgtc gggggtggcc agggcggtga ccacctgtcc
     3541 gagccactgc tcggcggtct cctcgaagtc gggctcgcag tcggtacggc cgacgaggcg
     3601 ggtggccccg agcgcgtcga gccgttcgtc gagccggcgg ccgtggccgc agaagtcgtc
     3661 gtaggtggag tcgcccaggg cgagcaccgc gtaccggatg ccctccagcg ggccgatggt
     3721 gggggcggag agcgcctgcc agaagtcggc accgttgtcg ggggcgtcgc cgtcgccgaa
     3781 ggtgctggtg atgagcaaca ggtcggtgtc ggggacgagt tgagcgggcg ccatgtccgt
     3841 catgggcagc agctctgggg tgcggcccgc cgccgtgagg tgggccgcgg cggtggtggc
     3901 gaactcctcg gcgttgccgg tctgcgaagc ccacaggatg accaggcgcc gggtcggtac
     3961 ggcggcgtcg gctgccgatg acgtggtccg cgcgggcccg agttcggact cgcgggtggc
     4021 gggtgcctgg gctacgggca ccgcggagcg ggagaacatg ccggcgaggg cgccgccgac
     4081 ccagagcgcg gaaccggggg agaggggcgc gtcggacggc agcacgggga cgtccccgtc
     4141 gggcgggttc agggcgaggc cggcgagata gccggagagg tagcggcgct ccggctcgac
     4201 cagtggtgcg ggggtcaggt cggtgatgcc gaacatcccg gcgagcgcgt ggacagcggc
     4261 gttcgaccgg gctgtcgcgc caccctggtc ggggacgggg tgcacgggct cgtcttcgtg
     4321 cgcggcggcg gccggcgtgg cctcggggcg ggtgcccggg cgggcccgcg ggacgggcgc
     4381 tgccgtcttg gtgagagtga cggcgcagac cttgaactcg ggttggaagg agatcgggtc
     4441 gatggcgtcg ttggtgacgg cgttgatgct gaggtactcg ccgaacaggt cgttccagtg
     4501 gaagggggcg aagcacgtac cgggtcgcac ccggtcggtg accacggcgg gaagcacggc
     4561 acgcccacgg cgggaggcga tctccacatg gtcgcccgcc gcgatcccga gcgccccggc
     4621 gtcctcgggg tggacctcca cgaacgggcc ggagccgagc ttggtgagct tggcgacctt
     4681 gccggtcttc gtcatggtgt gccactggtg ctgcaggcgg cccgtggtga gcatgaacgg
     4741 gtagtcgtca tcggggagtt cggccgcagg cagatgcggc cgggcgtaga accgggcgcg
     4801 tccgctcgcg gtggggaagg ccagccgggg gagcgtgccg tcctcgcgtt ccaccagtgt
     4861 ctggctgacg ccgttgttga ggtagcggat cgggttgcgg tccgggccgt ccgtggtcgg
     4921 cgccggccac tggaccggtg tggtgcgcag ccgctcgtag gtcaccccgc gcaggtccca
     4981 gccggtcgtg ggattccacg cctgcttgag ttcctcgaac acctcctcgg cagaggcgtg
     5041 gccgaatccc tcgccgaagc ccatctcgcg ggccaccctg gcgatcagct gccagtcggg
     5101 cagtgcctgt ccgggcgggt cgacgacgcc tggcaccagg gtgaggttcc gctcggagtt
     5161 gaccatgacg ccgtcggact ccgcccacag cgtcgcgggc aggacgacgt cggcgtacgc
     5221 gttggtctcg gtctcggcga agacgtcctg cgtgatgacg agttcggcgg cctccagacc
     5281 ggcgatgacg gtcttgcggt tggcgaccga ggcgaccgga ttggtgcaga tgatccaaca
     5341 tgccttgatg gcgccggcgg ccagttcctg gaacatctcg acggtgccgc gcccgacgtc
     5401 ggtacgcagc gagccctcgg gtatctgcca caggcgctcg acgaaggccc gctcggagtc
     5461 gaccagcacg gaccgctgac caggcagccc gggccccatg taccccatct cccggccgcc
     5521 catcgcgttg ggttggccgg tcagcgagaa cggtcccgat cccggacggc agatggcgcc
     5581 ggtcgccagg tgcaggttga ccagggcgtt ggtgttccag gtgccgtggg tggactggtt
     5641 caggcccatg gtccagcagc tcatccagtc acctgcctcg ccgatccact gcgcggcccg
     5701 gcggatgtcg ttctcggcga ggccggtgag ctccgcgacc cgctcgggcg ggtagtccgc
     5761 gaggaaggcg ggtatctcct cccagccctc ggtgaactcg gcgatgaact gctcgtcggt
     5821 gtggccgttc gccaccaaca ggtgcaacag gccgttcagc agggcgaggt cggtgcccgg
     5881 cctgatctgc aggaagaggt cggccttctc ggcggtggcg ttgcggcgcg ggtcgacgac
     5941 gatcaatctg gcgcctgcct tgacccggtc catcatgcgc aggaagagga tcgggtggca
     6001 gtcggccatg ttcgcgccga tgacgaagaa cacgtccgcg cgatcgaagt cctgatagga
     6061 gccgggcggg ccgtccgcgc ccagcgacag cttgtatccg gaccctgccg aggccatgca
     6121 cagccgcgag ttcgactcga tctggttggt gcgcacgaag cccttggcca gcttgttcgc
     6181 cagatactgc gcctccaggg acatctgccc ggacacatag aaggacaacg cgtccggccc
     6241 gtgctcgtcc aggatcgccc gcagccgccc ggccaccgac gcgatggcgt cgtccacttc
     6301 cgtctcgacg ggctgggcgc cgcgctcggc acgcaccagc gccttcgtca tgcgccccgg
     6361 cgcggccatc atgtccgcgc tggtcgcccc cttcgtgcac aggcggccgg agttggtggg
     6421 atgtgccctg tccccggacg ccttggccac ccggcgccgg ccgtcggcgg ggtcccgcac
     6481 cacgtccagg acgatcccgc agccgacccc gcagtacgag cagaccgtgc ggacactgcc
     6541 gtccttcgag ccagatgcca ccgaaacccc actccgcggt gcgtgtgcct tccccagcca
     6601 ggaccgcccc accggcggcg ggcacgacct acgaccagca ccgtagggag ggcgaatttc
     6661 cggcccgtca catgactgga gcgcccgagg ttacgcctcc cgcacacgcc gcaaccgcac
     6721 gatgtgaggc atggggtccc gttcacgccg gcgccccgca ccggcacatg cctgtgcggc
     6781 gccagacgcg acagcacctc ccacgccttg acgcctccac gcttcgcgcc acggtgctcg
     6841 atcacgacga gccgggccgc ccaaccgcca cgagcacgac gcgtcctagc ccgtctcgga
     6901 ctcttggaac tccaccacgg ccccgccgtg ctcgtgggcc cactgagtca gcacggcgat
     6961 cggctgcacc agggtccggc ccaagtccgt cagcacgtac tcgaccttcc cggccttggc
     7021 acggcggtcg acgaggccgt aaccctgcaa ccgccgcagc gtctgagtca gcaccttccg
     7081 ggagatcccg ccgatcagat cgaccaactc gccgtgccgg cacggttccc gactcaatgc
     7141 gaacaacacg accaccgccc acttgtcggc gatgatcgat cgccaaccga gccgggcagt
     7201 cagcgaggaa gacactgccg gagtactcat gcacgccccg atgctagccc gctgccaggt
     7261 acctgaaggt acctaccgcc tcattagcgt ccccagcgga agctaccgaa tcaggggaaa
     7321 cgcatgagta cagagatcga ctggccgggc gggaagaagg tcgccgcgct ggtcacagtt
     7381 gcgttggagc tgtggtcacc agggcacggt cccgcctacg cgccgatggc cgcggcgtgg
     7441 ccgctgtccg gcgtcgacga cacgcacagc acatcctggg tcgactacgg cgtcaccacc
     7501 ggcatctggc ggctgctcga caccctcggt gacctgcccg ccaccgtcgg cgtcaacggc
     7561 ctcgtcgccg agcggtaccc cgacacggtg gcggccgtgc accaggcggg gcacgagatc
     7621 gccgggcact cctggactta aggacgtcgt acccgcgctg ctcgacgtgg acaccgagcg
     7681 ggacaacatc cgccgctgca ccgacgtaat cgagcgagtc accggcgttc gccccaccgg
     7741 gtggacgagc ccgcgcgcca ccggctcgaa gcacacctgc gatctcctca cccaggccgg
     7801 ctaccgctgg accggcgacc acaacgaccg cgacctcccg caggtcctgc ccaccgccca
     7861 cggccccctg gtctccctca tgcacagcga ccactccgac gtccgcagcg ccgcggcagg
     7921 cccgtacgcc taccgcgacc tgcaccgtgt gctgctggac cacctgcgcg ccgcccccgg
     7981 cccaggcgtc ttccacttga ccgtccacgc ccacgtcgga cacgtcctta cctaccaggg
     8041 agttacgcga tgacccacgt cctcgtcgtg ggcggcaccg gagccatggg cagccacgtg
     8101 atccagcacc tgctcgccac caccggcgcc accatcaccg tccccacccg acacccggag
     8161 tccgctcacg ccaccgaact cgccgccacc gcgccccacc gcctgcgact ggtccgctcc
     8221 gacccagcgg ccctcgacgc cctgatgggg caggccgacc gcgtgttcgc caacaccgac
     8281 ttcttcgcga cgggcagcgc cgtgggtgag tatcggcagg gcctggagct gctgaccgcc
     8341 gcggagcggc cgctaccttc actcaggtca cgggcacccc cagcggctac ctcccgatgt
     8401 cgcacgacga actgcacgtc gccgtacctg acttcggcca cgactacgca gcgatgttcc
     8461 ggttcttcgc cgaccgtgat ctctaccgcc gagaccggga catcaccctt ctccgacgcc
     8521 tccaccccga cttgatgacc ttcgacgact ggctgcacca caccggatgg acgggatgac
     8581 cacccacgtc cgcgctcgtc gctccaaccg gcgccgtccc tctcttgcgt gacgccggtc
     8641 ctcgctcgcc ggcttcgtgc cgtatacgtc gccaccgttc cacggaccgc ctgcctgccc
     8701 gcgtgtgtgg acgggcgggc aggccgacac gcaggcttca ggcgcgaggc gggcggacct
     8761 cgatcacggt ggccgtgccg accgcaggcc ggccctcgtg catggtcatc acgtcaccgg
     8821 gcttcagttg ccgccactgc tcggggctca ggggagcgag ccggacgtcg gcggtctcgc
     8881 cgggaccgag ttcttggacg cactccaccc aaagacgtgc gatgcgcacc tctcgctgtc
     8941 cgtctgcggc gcggccaccg atgtcccaca ggggtctgag ctgaccatct cccgagaagg
     9001 cactccggcg tgcgccctcg tcggccccca acagggccag cctcgcgcgg acggtgccgg
     9061 agtggccgaa cggcgtggtg actcatcggc ggagcggctg cgcgaggcgc ggtgccgaca
     9121 ccgccccggg tcggcggtcc ggccggcgga cgagaccgtg aacgccgaca gtcagcgccc
     9181 acaccaggag ggggaagacc gcgacgcgct ccatgcctcc cataccgagg ccgaggtagc
     9241 gttcggtcag gaacagcccg aaggccgcga tcgctgcgcc gcccagcagg ccggtacccc
     9301 agcgcagtgg gcccgcaagg cgatccgtca ggctgaacgc ggccagcagg agcccgatgt
     9361 tgcccgtccc catgatgagc agggcgccca ggacgtgctg gctctcgttg acgtcagcgg
     9421 gggccagccc gaccaacacg aatcccacgc cggcgccggc cagcaacagc cgggacccgg
     9481 ccgcgagcgg tcccctgcgc cacaccacgc caccggccag ggcgacgccg acgacgagca
     9541 gcactcccag ggcgatgaac gaggcgttca tcaggccgtg ttcgggagag cagatgtagc
     9601 gcggctcggg atccggctgc agtgcacaga gcgcgttgcc caagtcgctg atgttgttcc
     9661 gtgcccagct gtacggtctc gcccaggccg actcgaccac gacgtgagcg gtgaagaact
     9721 gccccacccc cacgatccag gcgcagtacc cgatccgact cttcacctgt ccaccttccg
     9781 tcactcgaat cccgtgcggc cagcgcatca tgctgcgctg gtctccggca ctccgacagg
     9841 ccccctggaa cggggtgggg aagtccctac ctcggctgtg gcgccgcgga gggcaatgcg
     9901 tcggtagtcc caactgggcg agctccgacg cgagttcgag caccagctcg gggggcgtgc
     9961 ccggggccgt ccccggcacc agctccggca gcagttccgg tcactggtgg cggtcggcgg
    10021 cggagtccgc cagccgggcg agtcgcccgg tggccgacag gccgccgagg gccgcgcgtg
    10081 cctgggaggc gcaggctcgc gcctggcgtg ccgcctcggc gatggcgccg gtccgggcca
    10141 gcacgtcgag caggtcacgg tgggccgtgg cgagatcgac gttgccatgg aagatctcgg
    10201 tgaggtgtcg gcggtcgtgg gcgtccgcgg actcgtaggc gagcaggacg ggcagcgtcg
    10261 gctggcggtt ggcgacgtcg ctgacggcgg acttgccggt cagtgcgtcg tcggcggtgt
    10321 acggcaacag gtcgtcgcgg atctggaagg ccatgccgag ctgttccccg tagtggtgca
    10381 gggcgtcgat ctgctccggt gccgcgccgg ccaggatcgc gcccgcccgg caggcggcgc
    10441 cggtcagcgc ggcggtcttg ccgcggatca cctccagtac ggccgaccgc ccgcaggtca
    10501 ggtcctcgcg gatctcgatc tcgcgcatgc tggcgcggca catggcgtgg accgcctcgg
    10561 cgatcgcccg ggacgcggcc aggacacgat cggccgggcc gccgcggagc atggccgccc
    10621 accctgcggt gaacagcccg tctccggcga gcagggcctc ggcgatgccg aaccgttcgg
    10681 cggtcgacgc ccgcccgcgg cgtaccgggt cctggtcgac gatgtcgtcg tggacgaggc
    10741 tggccacgtg caggcattcg atggccgccg cgaaggacag caccgactcg gcccggccgc
    10801 ccaccgcccg tgccgattcc acgcacagcg tggggcgcag cagtttgccg ccggggaaca
    10861 gggcgtccag gcatgccgtt tccaacaggt cttcgccact gccgaccgag cggatcagct
    10921 cggcttcgat gagcgggatc agggggtcgg tgggccggga ggcggtggcg gtcatacggg
    10981 ggcctttcgg gttcagcagg ggatgatggt gcgccactgg cgctgccaca cgtcgaacag
    11041 cgcggagacg ggcgggcgta cgggccggtg cagcaggtcg gcgccggcgg cgcgcacgag
    11101 gccgagcagc agtgtgcagt gccggcccat ggcgtcggtc caggcactgg cgggactgtc
    11161 gtccaaggcg gtgaccaggg cggggaggcg gtgccggacg cgatcggcct cgaaggcgat
    11221 gactcgatcg tggcgagagc cgccgtgcca tacgcgtcca ggcgacgcgc ccgctcctcg
    11281 acgggcccgg tgtcggcgca cgcgtcggcc ttgtacccgt ggacgaccag cgccgcgaca
    11341 tgcggtcgga gcgccgccgg cgccgcccgc agcgcccacc aaccggccct cccctcatca
    11401 cacttgtgga tgtcacggat gcacaccgtg tagcacgggc gcaggacggg ggcatggatc
    11461 cccgccgcgt cgagccatcg tcgcaacagc accgcagggc cctcccctca cctcgtctcg
    11521 tgtccgcccg gcgcaggccg ggcagtgtgc tcatcgcgta ccgtgtgccg gccggcggcg
    11581 ggtcggtgtc cgagggcgcc gggtcctggg gaaggcgctg cgggtgcggc ggtggaacgc
    11641 cagcagggcc agcagcgcgg caccggcgaa ccacagcgtc tggacggcca ggcaactcgc
    11701 catcgtgccg ttcgtgaacc ccgcaccggt ggcggcctgc atgctcccgt aggacggcag
    11761 tagtcggacc agtggactgt tggcgccggt gttggcgatg gggttctgca gcgcgacgtc
    11821 gatgatgctg gtcatcacca tcgcgaacat gccctcgacc tcccgtcgca gtacgcaccc
    11881 gaagaggaca ccgagcgcgc cgtaggtcat ggcgtcgcag aacagcgcgg tggccagcag
    11941 cgccggctgg cgcgggatcc aggccgcgca ggtgacggcg gtggcgtaga ccgatacggc
    12001 agcgcaggcg agtgccagtg aggtggtctt ggccagggcg aggtggatgc gggggtggcc
    12061 tgccatggcc agtcgtcggt cgaagcgtcc accgttgaag gtggcggcga acatcatgaa
    12121 cccggcgatc agggtgacgg cgttgagggc gccggtgatc tgggagagct ggtcgccggg
    12181 cggggagagg aactcgccgg tggagttgag tcggacgggt gcgggtttgt cgggcagtgc
    12241 cgcgtgggcg agggtcaccc acgccgggac gtagaggacg accaggaaca tggcgaaccg
    12301 attgcgggcg tgcatgacca ggtcgtaccg ggcagccgtc acgaagaagg tcaggtgccg
    12361 cctcatggtg ccgcctccgc ccgcgggcgc agcactccgc cctccaggta ccacagctcg
    12421 tcgaggcggc cggtgtcgta ggcgaggtgg gacacgacca gcacggaccg gccggcctcg
    12481 cgcagcccgg ccgcgaggtc ccagaaccgc cggtaggtgt cccagtcgaa gccctggtag
    12541 ggctcgtcca gcagcagcac ctggggatcg tgcatcaggg cgagggtgag gttcagcttc
    12601 tggcgggtgc cgccgctgag cactccggcg cgttcgtcgg cgtactcgga gaaccgcagc
    12661 acctccatga ggccctcggc gcggcacaga tccgagaggc cgaaggcggt catgaagaac
    12721 ttcaggtgct gtcggacggt gagggcgtcg ttgaggacca cgtcctgtgg gcagtacccg
    12781 aagcggccgc ggtggacgac gacgccgcgc tgcggacgca gttcaccggc gaggatcttc
    12841 aacagagtcg acttgcccgc gccgttctcg cccacgatgc cggccaccac gccccgccga
    12901 aggctgatgt cgatcccgcg cagcaccacg cggcgcccat aagcatggtg cacacctttg
    12961 acgtccaacg cacttcccgc ccccaccccg cagcgacagc cctacatcga cagcgtcaca
    13021 tgtccaacga gtggcggccg ctcgcagccc cctcatgcgg gggctcggca gcccaatgtc
    13081 cgcatcgata cccggcaatg agcagaaata atcggaattc cgggaggggt gggcgcggag
    13141 gcgtaggtgg ttttcaggtg gcgtcatatt ctgttgtggc tgctgggaat tgagggaaac
    13201 gctcgcccgt catgcgtctt ggacgggggt gccctgatgg taaacgatgc gccacccgtc
    13261 gctcgcctgc tgccagatcg ttgacctgcg ggttctccgc ccgttgagca ccagggtgta
    13321 cgtcaggaga tacagatcgg cggccaactc ccggcaatgg aagtcggagg tctcccactc
    13381 ctcgacgggt ggctcctgag agcgctcctc aaggacatcg agtacatacg cgcggctgta
    13441 gcgttgcccc gaggcacccg tttcccagaa gtcgggcgcc gtcatggcct cgaaatcggc
    13501 tcgcgacatc ccgaactccg gcctgtggaa cagcggttcc ctgcccatga gttcggcgag
    13561 cacaccatgt agccgttcat cggtgacgcg atcgggttcc atcctcgatt gctaacagat
    13621 cacagtcggc ccggcaggtg ttttcgggaa gcgccctgcg cgtgtacagc tcccaggtat
    13681 gtgcctggag ccctcgtcct cgtcccacgt cgagacactg tccgcgaaga ccggtcacgg
    13741 ccgcgtactt gatgtcgcgg atgtaggcga ggaaggggcc ttgagtttcc gagagcgtgc
    13801 ctacggccag ggggcgttga tgcgaacagc tcgaacagcg cgcagagcgc gaacagcgtc
    13861 gaccggatga acggcatcga aggcgtcgaa gtcatcggtg agttcaccgg cccagttgcc
    13921 ggaagtcggt gcggcgccga ggctcaatgc gtgcggcggc cgtggtagat gaggcggtgg
    13981 ggggagaggt ccgtaccgta tccgcggtcg attccgacga gttcgaagcc cgcctgcgcg
    14041 agcgcttcgg cgaggttgag cgcactgtgg aaggcccagc gttccgtcac ctcggtcagt
    14101 acccggccgg atcgacggaa ctgcttctcg atcaccacgt ggtcggcgtg cagccggtgc
    14161 cgttcccatt cctccaccgg gccgccggct tcgcgacagg gctcggcgag accgatctgc
    14221 cagtcggtct ccgtccgcgc gtcgaaactc tcgctgacat cgatatggat ggagccccca
    14281 ggcgccagga cgcgggcggt ctccgccagg gcccgctgcc gatcgtgcgg cgttaccagc
    14341 agttggagcg tcgagtacgg gatgacggcg gtggcgtggg atccccggag cgggagcctg
    14401 cgcatgtccc cgcagaccgg gtgcagcccc ggcgtccggg gcatcctggc gagtcgctcc
    14461 cggctgaggt ccacggcggt cacccggcgt cgcgcggggt gcgccagggt gctcgccacg
    14521 cgtccggtgc cggccccgag gaccagcacg gtgtcgtgct gctcggtcag gcgggcccaa
    14581 taggcggtgt cgttgcgttg ccggcgcagc cggtgggcgt tgtgccagtc gtagagcaat
    14641 gcttcccact gcgcgggtgt cactgttcag ggctccttgt gaggcgcgtg agggagggga
    14701 aggaggggcc ggtcgcgggc cgggcgaacg gatggttccc gacggctggt tgctccgccg
    14761 tgtcgaggtg acggcgggcg gaatgggctg tcggatgggg aagtccgtgc catgctaccc
    14821 accggtcaaa tgcgctaccc gccgggcatt gccgctccgg cgcccgccgt gggaaatcgg
    14881 ccagcgacgg gactgttttt cccggactcg gcggtcgatg ttcgaggagt ccggctgggc
    14941 tgcgccaagg gcggcgcgga atcagtcgat attttctcgc ccactcggga aggcgcgata
    15001 ttttcgctct tttcgtgagt gtatgaatag tcggtcatgg gtctgcgtgc ggcttgtcat
    15061 gctggcctga ttcgatcgtc cgggtgccga gagagagcgt cggacgggca gcgggcttcc
    15121 ggagaatggt gttctcgcgg aagtgtcggg gtggcgtcac gcagtcgttg ttcgccgttc
    15181 ttcaggtggt aattcaaggg accgggaggg agttcggagg ggcgcggggt gggggttcgg
    15241 gggcattgtt cccggtgtgg cgtcgagtgg gggaccaggc gtcggtgttt cggccaaagg
    15301 cccaggtgcg gaccgagctt ggttgaccgc gtccaagtgg ccatgcttgg gtttccatga
    15361 atcgctgatt ggagaattcc tccctgcggt gaacgatgaa gtggtggagc agtggagcag
    15421 tgaagcggcg gagaagcggt ggtgtcgtgg actgcccgtc ccggtgggtg gcgcggtgtg
    15481 aacgctgcgc gttgtcgcga tgagtcgaaa agaaatgcgg aatccggggg gtgagaagag
    15541 tgggacggac atcggtgcaa acccagaccc aaccccagag ccaaacccgt acccgagccg
    15601 agatttggca agggttcggc gcagccgaaa ggcgggaggt cggcacggta atcgtgtcga
    15661 cgctgcagag ccagagcacc tccgcactgc tcctgcttct gctgtccctg ctcgcgctgc
    15721 gcgtgacggg ttcccccgcg agcgcacccc tggtcgtggc ggtcggcgca ttgcccgcac
    15781 tcctcctcgt ccgggcggtc cggatcgtca accaacgcgt cgaccaccgc tgggtgatgc
    15841 tgttgtcgga caccggagcg ttcgcggtgg ccgtgacgct ctggctgctg gtgcgcggcg
    15901 gtggggtgca cgcctggcag atctacgccg gcatgttcct cttcgcctcc ttcggggcct
    15961 tctacctccc cgccatgcgc gattgggtcg ccggccagac caccggcctg gagcaactga
    16021 cctggctgaa cgcgatgctg gccgtcgcca cccaggcatc cgtggtggtc ggctgggccc
    16081 tcgggggagt gctcgcgtcg tcgatcggca tccaggcgtc cttgggactg tgtgccctgt
    16141 cgtacgcggt cggcctggtg ctgcagttcg tggtgttcgt ggtgatcaac cgagcgccgc
    16201 tgcacaagtc cccggtcgcg gcggggtcgg ccggtcccgg cgcggcggag ccggacacca
    16261 gtggcgaagg gcggccgtcc gccgccgggg tgtggcggga ggtgttctcg ccccgccgcc
    16321 tgggattgtt caccgccgca ctgctgctca tggaactcgc ccacaccctc ggcttcagca
    16381 tgttcgtgcc gctgctgacc gggggcgcgt ccgaccggtc ctggatcgcg ggcacggcga
    16441 acgcctgctt cgccctcgcg gcgatgatca gcggagtgct cgtctccggc ggcacgttgg
    16501 gacggtggac ccgcgcacgg gtgccgcaga tcgtcctcgt cggcttctgt gtccaggtcg
    16561 tgttcggcct gagcgccgcg cacccggtgt gggcgatctg cctctacgcc gtggtgggcc
    16621 tgctcagcgg gggcgacgcg gcgctgcaga gcgaagtcca ggaccgttgg cgcccggccg
    16681 gatcggcgca ggcgttcgcc gtcttcggcg cggtgcaggg gccttcgcaa ctggtcggat
    16741 ccctcctcgt cgccgcactg ctgacctgcc tgtccgtggg gacggtctac ctcggcacga
    16801 tcgtggtgct gggcctgggc tcgggactgg tgctggtact ggccagatcg cgagccgcgg
    16861 ccgcctcacc acgggccgaa gcccccgtct gagatcccgc tgccgccggt ttccgtcgcc
    16921 gggaccggcc gtcgataccc gatggaactc acgaaaggaa cacgacgtgg ccaacctcgc
    16981 cctgtacggt ctcggcgaaa tgggggcgga catcgcgcgg tgcctggtgg cgcgcggagt
    17041 cgaactgcac gcctacgacc cggtggccga tgtggcgccg gaggcggacc acttccaccg
    17101 ctgcgcgaca gccgcggagg ccgcccgcgc cgccaccgtc cacctcgtcg tcgtcaagcg
    17161 accggacgac gtgcgcaccc tgctcttcgg cgccgacggg ctgtgcgccg ccgcgccccc
    17221 cggctcccac gtggtgctgc acaccaccct caccccgcag accgtccggg aactggccga
    17281 cgcggtgcgg caacaggggc acgtcctgct ggacgccgcg ctcagccgcc gtgacggcct
    17341 ggtccgcgac ggctcgctgt ccctgttcgt cggcgcctcg gcagcggaac tcggcaccgt
    17401 gcggccggta ctggaacgct acgccgacaa cgtcgtgcac gtcggaccga ccggcgccgg
    17461 gatgaccgtg aagctctgca acaactggct cctctacagc aaccggcacg ccgcgctcca
    17521 ggcactgcgc accggacgcg cactcggcgt cgaccccgac gtgctgcgcg gcgcgttggc
    17581 cgcctcgacc ggctccagct gggcactcgc gcactactcg gacctcgacg aggccatcgt
    17641 caccgggcag ggcgcaccgg ccgtggtgcg cgaccggacg acgtccgaac tacacatggc
    17701 ccgggagatg gcggccacca gcggccaggt gccgaccagc ctgcaggaga ccttcgcact
    17761 gctcgacgcg atgtgaacca cgtctcgccg ggcgccgctt cagccggccc cgcccgttcg
    17821 gaagggcccc atggacagtg acaccgtttc ccccgacgaa ctcgccaagg tcgtcgccgg
    17881 cctgcccgtg caggtgtgga actcgccgac ggcggccgaa ctctacgggc acaccctcaa
    17941 cctcgtctgc cggacccgcg ccgggcgcac cgcgggcgtc tgggtcgtcc cgctggacga
    18001 cggcggcacc gccgcccgcc gtcccttccg gctcctgccc tacgccgcac catggagcga
    18061 cccggggctg catcccgtgg accgccaccg tgcggtccac tcgatgaccc aggcgctgat
    18121 ggcccgcgtg gactcggcgg agctcccgat ggatccgcgc ttcggcgagg tggccgccct
    18181 gtgcgaagcc ggcgccgaac tgctctgccg gcacacccgc atccttgagc tgcgcgaggg
    18241 gtgcgacccg cgcagcgcgt acgtggccac cgcccggaac cacatccggg ccgcggcccg
    18301 acggcacacc gtgcacagcg ccccgctcga cagcttcgac ttctcccgcg cggtggtcgg
    18361 ccagccggcg ccggccgtgg ccgcccgacg ccgatccgga ctgcggatcg gccgggagga
    18421 accggcgctg tgcctcgccg cgacggaccc ggacggggtc tgccggggcc aggtgttcgt
    18481 actgctctgc gacggcgccg cggtcctcat gcactcctgg ttcgaccgca cgggtgcgcg
    18541 cggggtgccg agcctgctgg tcgacgaggc gatcacctgg gcgcaacggc agcccgggac
    18601 agaggtcttc gacttcgagg gcagtgtgct gcccagcatc gaccgcttca tgaccgggtt
    18661 cggcgcccac gcccgcggct atccgcaact gaggtggatc cgctcgggtc gacccggctc
    18721 ggacgcgggg gagttcggat gaccgccacc ggccgtccgg ccgaacccga cctcgacgcc
    18781 cgccgcccga ccgcggaccc cgcggcgccg cacccgctgc cgggcggccg ggccgtaccg
    18841 gaacccgagc cggcccacga cctgcgcctg gtcgacctcg acgccctccc cggagcccag
    18901 gaggacgcct gggcacgcgc ataccggcgc cacggcacgc ggctccagca gtctccggga
    18961 tacgcccacg cggtccgcgc cgcgggccac cgcgtggtcg tcgccctcgc ccccgacggc
    19021 atcgccgcct tcacccggga cggggacgtg ctcacggcgg tcggcgacga cgagcccctg
    19081 ctgaccgaac acggccaccc ggagcgactc gcccgcctgg tgacgtccgt ccgccgggcc
    19141 accggcgcgt cggtctacct ccccctggtg gccgcgcccc acgccgaagc ctgcgcccgg
    19201 gccggctgca cgacctggcg gcgaccgccc aactccctga tcgactggtc ccacgacggc
    19261 gccgacctgt gggaacgcgc cctggaacgg ggcagctccc aactccgccg caaacgacac
    19321 ctggtggagc gcgacggcct gaccgtacga ccgggccgat ccggtccgcg cgccttcgca
    19381 gacgtcctcg cggtcgacga ccgctcgtgg aaggccgcac ggggacagag catgcggcag
    19441 cgcggcggcc aggacgcgct ctacggccgg ctggtcgaca ccggagagat cacggccgcg
    19501 ttcctcctcg acggcgaacg ccccgtcgcc ttccggctgg acgcccgggt gcaggaccgg
    19561 ctgatgagcc tgaagtggtc ctacgacgag acctaccgac gctactcgcc cgggctctac
    19621 ctgctgacgg agggactccg gcaggagtgg gcgggccggg gcgtgtgcac ggtggacctc
    19681 cacggcagcc ccgacgcgct gaaggacctg ctccacaccg agcgcgtgcc gcgggcggac
    19741 gtgtggtgtg gtgcggccgg gccgggagcg ctccgagccc gggagcgcgc ggcgctggac
    19801 gcccgggtgg ccggcgccca cgaggcgggg aaggggctgc ggcatgcctt cgactgaccc
    19861 cgcggtggcc gccgccgtcc aggatctgct gcaccgttgg ggccagcccg ccgcggaatt
    19921 ctgcgcctcg ggcggcacgg cgctggaagc cgccctggag gtgctggagg tgggcgcggg
    19981 tgccgaggtg gtggtgcccg acgtcggctg ccactccgtc gccgccgccg tcgtccgctc
    20041 cggcgcggtg ccggtgttcg tcggcgtcgg cgaggacctg accctgcacc gggacgacgt
    20101 ggccgcggcc tgctccgcac gcacccgcgc ggtcatcgcg gtgcaccagt acggactgcc
    20161 gtgcgacgtc accggcatcg cccggtcact gcccccggac gtggtggtga tcgaggacgt
    20221 ggcgcagacc tggggatcga cgacgcgggg cgtgcccgcc ggagccaccg gcacgctcac
    20281 cgtcgcctcc ttcggcccct ccaaaccggt gtcgctcggt gccgggggag cgctcctcgg
    20341 cccggccgac ctggtctccg gagcggtcgc ccggggcgac acgacggacc ggcaccggcc
    20401 gcgccccccg tcgcccgcgc gcttccccgc ccccctgctg cccctgctcc cggacgccat
    20461 cgcccgcgcc gaccggcaac tcgcccgccg cagggcggtg gtcgaccgct tccgggacag
    20521 tgacctcgcc cgacacttcc gccttccgcc cctgccgccc ggatccagcg ccggctggac
    20581 ccggctgccg ctctacccgg cgccgtccgc caccgcccgc cacatcgggc aactggccga
    20641 cgacctcggc tccgtgcagc cgatgcaccc gcaaccaccg tccgcactgc cgatgttcca
    20701 ccggtgcgag aagcgcgtcc tgaccggcgg ccggcggcct gtggaacccc ttctcgtcaa
    20761 gattggatga tcccacatga cgctgatcaa cccccatcag ttcttcgacc tgtcgcagga
    20821 ggatccgcag tccctcaccc acttccgggc gaccctcgcc gacggccagc tcttccgcta
    20881 cgtcgaaggg gaccgcgagt ccgccaacac gctcatcgag cgccacttcg ccggctactt
    20941 ccgtaaggag gccgccacgg cggtggccaa cggca
//
