LOCUS       NZ_CP054019            20908 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. A1-5 chromosome.
ACCESSION   NZ_CP054019
VERSION     NZ_CP054019.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. A1-5
  ORGANISM  Streptomyces sp. A1-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9459690)
  AUTHORS   Dashti,Y., Sumang,F.A.M., de los Santos,E.L.C., Alcantara,E.P. and
            Challis,G.L.
  TITLE     Structural revision and biosynthesis of polyketides FXJ15321 and
            FXJ15322 from Streptomyces sp. A1-5
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9459690)
  AUTHORS   de los Santos,E.L.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2020) Warwick Integrative Synthetic Biology
            Centre, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL,
            United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUN-2019
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:28:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,328
            CDSs (total)                      :: 8,230
            Genes (coding)                    :: 7,847
            CDSs (with protein)               :: 7,847
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 383
            CDSs (without protein)            :: 383
            Pseudo Genes (ambiguous residues) :: 0 of 383
            Pseudo Genes (frameshifted)       :: 156 of 383
            Pseudo Genes (incomplete)         :: 280 of 383
            Pseudo Genes (internal stop)      :: 26 of 383
            Pseudo Genes (multiple problems)  :: 73 of 383
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:08:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5138580
            Orig. end                         :: 5159488
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Philippine National
            Collection of Microorganisms.
FEATURES             Location/Qualifiers
     region          1..20908
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="18"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20908
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20908
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10908](+)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10908
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     gene            455..1165
                     /locus_tag="HRD51_RS23030"
                     /old_locus_tag="HRD51_22700"
     CDS             455..1165
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018536453.1"
                     /locus_tag="HRD51_RS23030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22700"
                     /product="VTT domain-containing protein"
                     /protein_id="WP_205366089.1"
                     /transl_table=11
                     /translation="MNTLALGPQWLNSDYLITTFGLIGVLLIVFAESGLLIGFFLPGDS
                     LLFTTGLMVTTNKIDKPLWLVCALVVLAAVLGDQAGYLFGRKVGPSLFKRPDSRLFKQE
                     NVEKAHAFFEKHGPKSLILARFVPIVRTFTPIIAGVSRMQYRSFIIFNIIGGTLWGAGV
                     TLLGAALGNVDFVHKHIELILVAIVLISVVPVVIEFLRARSKAKKEPATDAAMDAPLAA
                     AQARPQGRGRHAKR"
     gene            1845..3509
                     /locus_tag="HRD51_RS23035"
                     /old_locus_tag="HRD51_22705"
     CDS             1845..3509
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850455.1"
                     /locus_tag="HRD51_RS23035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22705"
                     /product="threonine/serine exporter family protein"
                     /protein_id="WP_235096065.1"
                     /transl_table=11
                     /translation="MSEPAGLPEDRKPQSDEAHSAFTPPLGVPLPPTPEEEHPTSEFAL
                     PEGLRAEAPAEPEGSAFARPGGTTGQTPLPTFTPPHGIPVLSLTKEAPWQDRMRTMLRM
                     PIHERPVPERAERTEEEGGGPAVPRVLDLTLRIGEILLAGGEGAEDVEAAMFGVAHAYG
                     LERVEPTVTFTLLSISYQPSLVEDPLTASRTVRRRGVDYTRLSAVFRLVDDITSEGISL
                     EEAYRGLAEIRRNRHPYPSWALTVSSGLLSGAASMLVGGGVLVFIAAAIGSMLGDRLAW
                     LASARGLPEFYQFVVAAMPPAGMGLAFALAHSNVQSSAVITGGLFALIPGRALVASVQD
                     GLTGYYITASARLLEVGYLIVGIVVGVLSVLYLGLQADPGLKRLNPEQALQLYNEPVVQ
                     TIASMLLALAFCVLLQQERHTVAFATLNGGVAWVVYGALTATAGFNAVPSTAIAAGLVG
                     LFGQLLSRYRYASALPYVTAAIGPLLPGSATYFGLLNFAQGNLLEGFSSLIKAASLALA
                     IAVGVNLGGEVARLFLRAPLAVEPGGERRAAKRTRGF"
     misc_feature    complement(3692..3703)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    3790..3810
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(3850..3865)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            3882..5819
                     /locus_tag="HRD51_RS23040"
                     /old_locus_tag="HRD51_22710"
     CDS             3882..5819
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991974.1"
                     /locus_tag="HRD51_RS23040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22710"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_205366090.1"
                     /transl_table=11
                     /translation="MARRVANTNQRSGAAPGAGRVGSVAKRQTALLGTGVALGLLGVGA
                     TLAQPWAIGKLIGAVSAGASLTGSIITVAALFCLGAFFSALQSYVIGRAGENIVYDVRH
                     GLVGRLLRADLAEFGKWPQGDIVTRTVTDTSLVKIALSQSLAQLVISGATTIGCVVLMC
                     TIDLSLMLITLASLGVASTLAIVLARKLRGAALQNRDDTGAFGSGVQRVLSALPTVKAS
                     RAEPRETARIGALAERARRSGIRVNAYNALLVPSMNVGTQGALAVVVGAGMAWVARGEM
                     SMADLTTFVMYLFQLVSPLVMVFMAIGQFVQGRAAIERVDKLAGLPQEGGGAADAGQGL
                     APTGPLPAHHPAIEFHDVRFGYRRGEPAAVTQVLHGVSLSVPARGLTAVVGPSGAGKTT
                     LFQLIERFYRVDGGRVLLGGRDVEGLPLETLRGLVGYVQQDSAAMRGTVRENLTYAQPH
                     ASEDDIREALEMAGLGAVVAGLPQGLETELGDQGSGLSGGQRQRLCIARTLLQKPAVML
                     LDEATSHLDSDSERAFRDVLRRVSRQCAVIAIAHRISTVIDAEKIVVLEDGRVRATGVH
                     RDLMENDALYRRLAGSQLHAESGPAATAGDRARGEPGAGPLPSAVGRPPWGGLNEQTVR
                     LRPIGIEEQW"
     gene            5816..7300
                     /locus_tag="HRD51_RS23045"
                     /old_locus_tag="HRD51_22715"
     CDS             5816..7300
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453459.1"
                     /locus_tag="HRD51_RS23045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22715"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_205366091.1"
                     /transl_table=11
                     /translation="MNSTDVAIVGTGPNGLAAGVVLARAGLRVELYEAAETIGGGLRTA
                     SLFDTGVVHDICSAVHPMAAASPFFRAFDLAARGVELLHPEISYAHPLDGGRAALAYRS
                     LADTCAHLGPDGPRWRRLMGPLLEHSEAVVDLILSGQRSLPRDPAAALLLAGRVAVHGT
                     RLGAAYFQGEEAAALLTGVAAHAVGKLPSFAGGAVAMLLGHLAHGTGWPLPRGGSGRIA
                     EAMARDIAAHGGVFHTGHPVTDLAELRGARAVLLDTSPKGFLALAGDRLPRSYARGLAR
                     FRYGPGAAKVDFLVSEPIPWSDPAVGRAGTVHLGGTHAEMVRQETKNARRVRTREPFVL
                     LVDPAVADPGRALPGKRPVWAYAHVPNGDPTDPHALVRARIERYAPGFGDTVLAHRSVP
                     AASYETYNPNYVGGDIGSGAMTLYQSLARPVPRFDPYRTPLPGVFLCSSATPPGPSVHG
                     MSGYLAAVSALRHCFRTYDIPDVGPKSALLTGACPR"
     gene            7765..8523
                     /locus_tag="HRD51_RS23050"
                     /old_locus_tag="HRD51_22720"
     CDS             7765..8523
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991976.1"
                     /locus_tag="HRD51_RS23050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22720"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_205366092.1"
                     /transl_table=11
                     /translation="MTNGVEDIGYGRQFAGWYDRLIPDDEVTAEAVKGLLALHPAPEAG
                     TIELGVGTGRIAVPLSESVGRVTGVDSSPEMLDAMRVKLKERGDVTPVHGDIRSYTSDS
                     RYGLVYCVCATLSLLHTPEDQLLAVRRAADLLAPGGRLVIETHNKPPILELHEGRKRTT
                     YFVPYPEPGTGVQTHSTLLDGDLWHCSHILYQADGTTRVGSELTRLTTPEEIDAYARAA
                     GLEPETHLSRWDGTPYNEQSPMFVCCYVKS"
     gene            8562..8909
                     /locus_tag="HRD51_RS23055"
                     /old_locus_tag="HRD51_22725"
     CDS             8562..8909
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013677.4"
                     /locus_tag="HRD51_RS23055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22725"
                     /product="transposase"
                     /protein_id="WP_268826401.1"
                     /transl_table=11
                     /translation="MGRPPILPADKKLGLLVRVMSGQLTAAEAAREVGVSEQSVSNWRR
                     QFIEGARNGLAGESGKDSEEASRIAELTQENAMLKATIGELYMELRKSGRGTPGHVPQP
                     CGKTRPARRVN"
     misc_feature    8912..8921
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.63"
                     /tool="antismash"
     gene            9099..10004
                     /locus_tag="HRD51_RS23060"
                     /old_locus_tag="HRD51_22730"
     CDS             9099..10004
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (22-153). E-value:
                     3.5e-12. Score: 38.4. Matches aSDomain:
                     nrpspksdomains_HRD51_RS23060_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991978.1"
                     /locus_tag="HRD51_RS23060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22730"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_235093993.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 8.5e-15, bitscore:
                     54.9, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.2e-08, bitscore: 33.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHERPDGSLVEVDVSIPSQARRVVLLDNGLGAPHEYWDWVCDALP
                     ADMGYVRFNRPGYGLSTPVAQYGLHRHYALLQELRDTYVPGLPVVLAGHSLGGYFVAAY
                     ASRHPGALEGVSAVVMIDATEVTSLRHSRRTDIDRWARQSLVMEQAYAWAGLSAFRPAK
                     NVNQQYRPEINRSYTAFLTNPRSWATAHREYRDAMTYPELTDLDCPLTVVTAENNVGDN
                     TMHHAVQARLAAISKRSRHHFIEGSDHESALAVPDHARQVAEVIAGEPPTGRTGPERRQ
                     TATKDRPAAVRDTEREEELT"
     aSDomain        9165..9557
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS23060_Abhydrolase_1.1"
                     /evalue="3.50E-12"
                     /label="HRD51_RS23060_Abhydrolase_1.1"
                     /locus_tag="HRD51_RS23060"
                     /protein_end="153"
                     /protein_start="22"
                     /score="38.4"
                     /tool="antismash"
                     /translation="VVLLDNGLGAPHEYWDWVCDALPADMGYVRFNRPGYGLSTPVAQY
                     GLHRHYALLQELRDTYVPGLPVVLAGHSLGGYFVAAYASRHPGALEGVSAVVMIDATEV
                     TSLRHSRRTDIDRWARQSLVMEQAYAW"
     CDS_motif       9360..9395
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS23060_0001"
                     /evalue="8.90E-04"
                     /label="NRPS-te1"
                     /locus_tag="HRD51_RS23060"
                     /protein_end="99"
                     /protein_start="87"
                     /score="11.9"
                     /tool="antismash"
                     /translation="PVVLAGHSLGGY"
     gene            10001..10582
                     /locus_tag="HRD51_RS23065"
                     /old_locus_tag="HRD51_22735"
     CDS             10001..10582
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604050.1"
                     /locus_tag="HRD51_RS23065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22735"
                     /product="hypothetical protein"
                     /protein_id="WP_235093994.1"
                     /sec_met_domain="cypI (E-value: 9.9e-28, bitscore: 96.1,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVNTERLKTAVVTASIAAWLVATAAGQLPENRFDNLLRRGRWQI
                     PVPNWRFFGPNPGVKDNHLLYRDITDGRPGDWTEVEITRDRPWYALVWNARNRCPKALF
                     DASQDTISRSVAFGPELRLVTLGSGYQLLSRYIQRHLPHAEGASHSQFMLMQSYLNAPG
                     DRQINPVFVSVEFPLTEDATPDAAAFPLAA"
     gene            10711..10908
                     /locus_tag="HRD51_RS23070"
                     /old_locus_tag="HRD51_22740"
     CDS             10711..10908
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypemycin"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033402.1"
                     /locus_tag="HRD51_RS23070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22740"
                     /product="linaridin family RiPP"
                     /protein_id="WP_159030869.1"
                     /sec_met_domain="cypemycin (E-value: 1e-12, bitscore: 47.1,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVVAEFANTQLVDVKPGRIGSDAAPTMMTPLATVATPEAVSAGI
                     AVTSATAAALNMVTHNVQHG"
     gene            11195..11920
                     /locus_tag="HRD51_RS23075"
                     /old_locus_tag="HRD51_22745"
     CDS             11195..11920
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604049.1"
                     /locus_tag="HRD51_RS23075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22745"
                     /product="hypothetical protein"
                     /protein_id="WP_235093995.1"
                     /transl_table=11
                     /translation="MRPKFAKRFPRLTRALSSKKAAVALYGVQAGASAATLIWGHKRAV
                     RTTGSAVLAVTGAAGRLHTPFGGDGADQLQQVVNVVLASTGTFKDGEKARDVAMRALAL
                     ETTISYVASGVVKLVSPVWLSGEAFSGVIRTHNYGDPHLFQLVHKYPLLGKLITWGTVA
                     AEVGFPLVFVLPKPAARAWLGSMSLFHLGIGQFMGLNRFVLAFGATHPAILYVLDRSEG
                     RAALTGRTSAAVTSAPAAA"
     misc_feature    12054..12070
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.37"
                     /tool="antismash"
     gene            12073..12399
                     /locus_tag="HRD51_RS23080"
                     /old_locus_tag="HRD51_22750"
     CDS             12073..12399
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS23080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_22750"
                     /product="hypothetical protein"
                     /protein_id="WP_235093996.1"
                     /transl_table=11
                     /translation="MKRITMAAGVAVAGAMLAVSAQAGAQAAPLPRTTVADAAAVTPSA
                     AQGDWNPPAGYTLERSFLGDSASCSKEGDAGVAAGKWHQYVCHEQMMKLTDTWMLFQFL
                     YVKK"
     gene            complement(12565..13056)
                     /locus_tag="HRD51_RS23085"
                     /old_locus_tag="HRD51_22755"
     CDS             complement(12565..13056)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003991985.1"
                     /locus_tag="HRD51_RS23085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22755"
                     /product="inorganic diphosphatase"
                     /protein_id="WP_039634169.1"
                     /transl_table=11
                     /translation="MEFDVTIEIPKGSRNKYEVDHETGRIRLDRRLFTSTSYPADYGFV
                     ENTLGEDGDPLDALVILDEPTFPGCLIKCRAIGMFRMTDEAGGDDKLLCVPASDPRVEH
                     LRDIHHVSEFDRLEIQHFFEVYKDLEPGKSVEGANWVGRTDAEAEIERSYKRFEAHGGH
                     "
     gene            13143..14759
                     /gene="dacB"
                     /locus_tag="HRD51_RS23090"
                     /old_locus_tag="HRD51_22760"
     CDS             13143..14759
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090095.1"
                     /locus_tag="HRD51_RS23090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22760"
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_205366096.1"
                     /transl_table=11
                     /translation="MPETRTWQVTWQSAQRSARVAARRAGRSARTAARTAQRAAHATTG
                     AAQHAWQAAPRQTRQTWQLTAASAATGLAVAVVAVAAAGPWDSGQRTAERAAAVPAPAT
                     GGEHHDDGRAPGPAPSAPAVLTALGGPARGAVGRGGAAPAPTDAGLADALSPLLSDPAL
                     GPLRTASVVDVAAGRQVFGEKQDEAATPASTVKLATAVAALSRLGADHRIDTGVVLAGK
                     DRIVLVGGGDPTLTARAAGPGPDERPASLRDLADATAHALQQRKLTTVGLGYDASAYTG
                     PAEHPIGPNENIAPVAALMTDEARLDDSDHGTAPRSTDPAGDAARTFAGLLKERGITVT
                     GDPAEARAPKSPDRIAVVRSLPLSALVERMLTYSDNDIAEALARQTALAAHQPASFDGA
                     AKAVRDALAAQHLPLTDAVFEDGSGLDRDDKVSANLLSRLLLAAAAPDKPELRPVLTGL
                     PVAAFTGTLRGRYVGDTAGAGTVRAKTGTLTGVNSLAGTVVDADGRLLAFAFMTTGTTD
                     PQAAQKALDRMASTVANCGCR"
     misc_feature    complement(13167..13177)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.07"
                     /tool="antismash"
     gene            14874..16019
                     /locus_tag="HRD51_RS23095"
                     /old_locus_tag="HRD51_22765"
     CDS             14874..16019
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540388.1"
                     /locus_tag="HRD51_RS23095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22765"
                     /product="zinc-dependent metalloprotease"
                     /protein_id="WP_235093997.1"
                     /transl_table=11
                     /translation="MTSIGGVEMVDWNLAVATATRFVRPGPEVSRDEARAIVAELRRHA
                     KSSEEHVRGFTRMAQPGAEGGAVSHDTPVLVVDRPGWIRANVAGFRAVLKPLLAKMEDR
                     RSSTPGGAVLGAVGGKVTGVELGMLLSFLASRVLGQYETFAPASRDLPAGTQGGRLLLV
                     APNIVHVERELDVAPHDFRLWVCLHEETHRTQFSAVPWLRDHIEGEIQSFLSETDIDPG
                     TLLERLREAAQSLAGAKPEGEEGEESRSLVDVVQTPVQREILGRLTAVMSLLEGHADYV
                     MDGVGPEVVPSVAEIREKFQKRRASGAGRLDQALRKLLGLDAKLRQYRDGERFVRSVVE
                     EVGMDGFNRVWTSPNTLPTKQEIAKPADWVARVHRKADGAQ"
     gene            16213..17220
                     /gene="tilS"
                     /locus_tag="HRD51_RS23100"
                     /old_locus_tag="HRD51_22770"
     CDS             16213..17220
                     /EC_number="6.3.4.19"
                     /GO_function="GO:0016879 - ligase activity, forming
                     carbon-nitrogen bonds [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="tilS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540389.1"
                     /locus_tag="HRD51_RS23100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22770"
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="WP_235093998.1"
                     /transl_table=11
                     /translation="MGPHPAVAAIRLAVRRVLHDVLTHHCAQDRREAPLVLVACSGGAD
                     SMALASALAFEAPKLGVRAGGVTIDHGLQEGSDLRAAEVALRLRALKLDPVDIVSVEVG
                     RVGGPEAAARDARYAALDATADRHGASAILLGHTRDDQAETVLLGLARGSGIRSLSGMA
                     AATGTNGRYRRPFLDVDRQTARTACLIQALPVWDDPHNTDPAYTRSRLRHEGLPALEKC
                     LGKGVVEALARTAQLSRDDADALDGWAADAEVTVLDEAGTLDVAGLFALPAAVRRRVLR
                     RAVIAAGSPAGSLFARHIEEVDRLITAWRGQGAINLPGRVGVRRQGGRLVIRQG"
     misc_feature    17287..17302
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.27"
                     /tool="antismash"
     gene            17335..17874
                     /gene="hpt"
                     /locus_tag="HRD51_RS23105"
                     /old_locus_tag="HRD51_22775"
     CDS             17335..17874
                     /EC_number="2.4.2.8"
                     /GO_process="GO:0006166 - purine ribonucleoside salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016472926.1"
                     /locus_tag="HRD51_RS23105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22775"
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="WP_039641113.1"
                     /transl_table=11
                     /translation="MGADLQSVLITKEEIDAKLAELAAKIDAEYAGKDLLIVGVLKGAV
                     MVMADLARALSNPVTMDWMAVSSYGAGTQSSGVVRILKDLDTDIKGKHVLIVEDIIDSG
                     LTLSWLLSNLGSREPASLEVCTLLRKPDAAKVAIDVKWIGFDIPNEFVVGYGLDFAEKY
                     RNLPFVGTLSPHVYGG"
     gene            18158..20164
                     /gene="ftsH"
                     /locus_tag="HRD51_RS23110"
                     /old_locus_tag="HRD51_22780"
     CDS             18158..20164
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0051301 - cell division [Evidence IEA]"
                     /codon_start=1
                     /gene="ftsH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006604043.1"
                     /locus_tag="HRD51_RS23110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22780"
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="WP_205366099.1"
                     /transl_table=11
                     /translation="MDVKRYFRGPVMWIVLAVLAVVVLMQVVGSSGGYKTVDTGQVVKA
                     IADNKVKSAELTTGDENKIKIELSGDNKIAGSNKIQASYIGDQGVDLAKNLQAKYQTGE
                     IKDGYTVSPSKQNPFVSVIITLLPFILIPVIFLILMNQMQGGGSRVMNFGKSKAKLITK
                     DTPKTTFADVAGADEAVEELHEIKEFLQEPAKFQAVGAKIPKGVLLYGPPGTGKTLLAR
                     AVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFEQAKANAPAIVFVDEIDAVGRHRGA
                     GLGGGHDEREQTLNQLLVEMDGFDVKGGVILIAATNRPDILDPALLRPGRFDRQIAVDR
                     PDLQGRLEILKVHQKGKPVAPDVDLSAVAKRTPGFTGADLSNVLNEAALLTARSDKKLI
                     DNHFLDEAIDRVVAGPQKRTRIMSEKEKKITAYHEGGHALVAAASPNSDPVHKITILSR
                     GRALGYTMVLPDEDKYSTTRNEMLDQLAYMLGGRAAEELVFHDPTTGAANDIEKATATA
                     RAMVTQYGMTERLGAIKFGTDNSEPFLGREMAHQRDYSEEVAALVDEEVKKLIETAHNE
                     AWEILVENRDVLDNLVLELLEKETLNKEQIAEVFKHIVKRPARPAWTGSSRRTPSTRPP
                     VLTPKELAPANGSAASSVSMEKTDTSEEPRSES"
     gene            20271..20876
                     /gene="folE"
                     /locus_tag="HRD51_RS23115"
                     /old_locus_tag="HRD51_22785"
     CDS             20271..20876
                     /EC_number="3.5.4.16"
                     /GO_function="GO:0003934 - GTP cyclohydrolase I activity
                     [Evidence IEA]"
                     /GO_process="GO:0042559 - pteridine-containing compound
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0046654 - tetrahydrofolate biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="folE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GTP_cyclohydroI"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014178504.1"
                     /locus_tag="HRD51_RS23115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_22785"
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="WP_205366100.1"
                     /sec_met_domain="GTP_cyclohydroI (E-value: 1.8e-77,
                     bitscore: 257.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDPVTLDVEGAIGTFDEKRAQNAVRELLIAVGEDPDREGLLETP
                     ARVARAYKELFAGLWQKPEDVLTTTFDLGHDEMVLVKDIEVVSNCEHHLVPFVGVAHVG
                     YIPSTDGKITGLSKLARLVDVFARRPQVQERLTTQIAESLMQILEPRGVIVVIECEHMC
                     MTMRGVRKPGAKTTTSAVRGQLRDPATRAEAMSLILAR"
ORIGIN
        1 agaccgcgca gctcaccgcc gatcatcgac ttcaggcccg cgccgatctg gctgccgagg
       61 tgccgggagc gcacggtgag gccgaagacc tcgccgatca cttgtttcac gtgaaacccc
      121 ggcacgtcgt tggtcgtcac caccaggacg tcggactgct cgtgctgtcc gccgccgtac
      181 tcctcgatgc ccatggtccg cacctcctgt ccttgcggtc aggatcaccc gggccggccg
      241 gagcggccag cgctcggggg cgctcgggtg ggggtcggcg gccagcgtcg aggcggggcg
      301 gggcggcccg ggaggccgtg gccgggggtg ctcctggaac cacgggacgt catagtccgt
      361 tgatagcttt gggccgcaca ctgcgcctgc acccctcgct tccgctcgcc gcgccgcgcg
      421 agccgggcgc cctcgaccca ggagccttca ccccgtgaat actctcgcgc tcggccccca
      481 gtggctgaac tcggactact tgatcacgac attcggcctg atcggcgtcc tgctcattgt
      541 gttcgcggag tcggggctgc tgatcggttt cttcctgccc ggggactcgc tgctgttcac
      601 caccggcctg atggtgacga cgaacaagat cgacaagccg ctgtggctgg tgtgtgcgct
      661 ggtggtgctg gcggccgtcc tgggtgacca ggccggatac ctcttcgggc gcaaggtcgg
      721 cccctcgctc ttcaagcggc ccgactcccg cctcttcaag caggagaacg tcgagaaggc
      781 gcatgccttc ttcgagaagc acggtccgaa gtcgctgatc ctggcccgat tcgtcccgat
      841 tgtgcggacg ttcacgccga tcatcgcggg cgtgagccgg atgcagtacc gctccttcat
      901 catcttcaac atcatcggcg ggacgctgtg gggcgccggc gtgacgctgc tgggcgccgc
      961 gctgggcaac gtcgacttcg tgcacaagca catcgagctg atcctcgtgg cgatcgtgct
     1021 catctccgtg gtgccggtcg tcatcgagtt cctgcgggcg cgctccaagg ccaagaagga
     1081 gccggcgacc gacgcggcga tggacgcccc gttggccgcg gcccaggccc gtccgcaggg
     1141 gcgggggcgc cacgccaagc gctagcgctt ggcgctggcg cttggcgtgc atcccacgtc
     1201 gtcggctccc ccgtcgtagg ggttcgcctt tcttgcgcct gcggcgcggg tccgctgcgc
     1261 ggggcttttc ggccgcggtg ccggttctgt ggggtggggg atgtgcggac tgctgcgctt
     1321 tacgtccgca catcccccac cccacagaac cgtcccctcc cgttggtggg tgggtttcag
     1381 gccgtagggg tacgcctggg tggtcccctg cgggttcgtc gtggagcggt ggcgaccgtc
     1441 aggggaccac tcgcgtaggc ccccactcac cgtctttccc acccacctac gggaggtgcc
     1501 gggtctgcgg ggtgggggtg tccggactgc tgcgctttac gtccggacac ccccaccccg
     1561 cagacccggc accgcaccgg acagccccgc gcagcggacc ggcagcggac cccccgccgt
     1621 caggcggccc cgcgccgcag gcgcaagaaa ggcgaacccc tacggcgggg cagccgacaa
     1681 cgtgggaagc gcgccaagcg cagcggaccg gcccccgaag gagcgccgtc cgcagccatg
     1741 cggcatcgtg tgcatgacca gtcggcagga ggcacaggca cgaggagcgg agagacgtgg
     1801 cgtcggatcc accacgcggt aagggcaagg gcaagggcag cggcatctcg gagccggccg
     1861 gtcttcccga ggaccgcaag ccgcagtcgg acgaggcgca cagcgccttc acgccgccgt
     1921 tgggtgtgcc gttgccgccg acgcccgaag aggagcaccc gacctcggag ttcgcgttgc
     1981 ccgaggggct ccgggcggag gcgccggccg agcccgaggg gtcggcgttc gcccggccgg
     2041 ggggcaccac cgggcagacc ccgctgccga cgttcacgcc gccgcacggc ataccggtcc
     2101 tcagcctgac caaggaagcg ccgtggcagg accggatgcg caccatgctg cggatgccga
     2161 tccacgagcg accggtgccc gagcgcgcgg agcgcaccga ggaggagggc ggcggccccg
     2221 ccgtgccccg cgtcctggac ctgacgctgc gtatcggcga gatcctgctg gccggtggcg
     2281 agggtgccga ggacgtcgag gcggcgatgt tcggtgtggc gcacgcctac gggctggagc
     2341 gggtcgagcc gaccgtcacc ttcaccctgc tgtcgatctc gtaccagccg tccctggtgg
     2401 aggacccgct caccgccagt cggacggtgc ggcggcgcgg cgtggactac acccggctgt
     2461 cggccgtttt ccggctggtg gacgacatca cctcggaggg gatcagcctc gaagaggcgt
     2521 accgcgggct ggcggagatc cgccgtaacc ggcacccgta cccgagctgg gcgctgacgg
     2581 tgtcctccgg gctgctctcc ggcgcggcga gcatgttggt cggcggcggg gtgctggtgt
     2641 tcatcgcggc ggcgatcggc tcgatgctcg gcgaccggct ggcctggttg gcgtcggcgc
     2701 gcgggctgcc ggagttctac cagttcgtgg tcgcggcgat gccgcccgcc gggatggggc
     2761 tggccttcgc cctggcccat tccaatgtgc agtcctccgc ggtgatcacc ggtgggctgt
     2821 tcgccctgat cccggggcgg gcgctggtcg ccagcgtgca ggacgggctg accggttact
     2881 acatcaccgc ctccgcgcga ctgctggagg tcggctatct gatcgtcggc atcgtcgtcg
     2941 gcgtgctgtc cgtgctctac ctcgggctgc aggccgatcc cggtctgaag cggctcaacc
     3001 ccgagcaggc gctgcagctg tacaacgagc cggtggtgca gaccatagcg tcgatgctgc
     3061 tggcgctggc gttctgcgtc ctgctccagc aggagcggca cacggtggcg ttcgcgacgc
     3121 tcaacggcgg ggtcgcctgg gtggtgtacg gggcgctgac cgccaccgcc ggcttcaacg
     3181 cggtgccctc cacggccatc gccgccgggc tcgtcggcct cttcgggcag ttgctctccc
     3241 ggtaccgcta cgcctccgcg ctgccctatg tgacggcggc gatcggcccg ttgctccctg
     3301 gtagcgcgac ctacttcggg ctgttgaact tcgcccaggg caatctgctg gagggcttct
     3361 cgtcgctgat caaggccgcc tcgctggcgc tggcgatcgc ggtcggcgtg aacctcggtg
     3421 gcgaggtcgc ccggctgttc ctgcgggcgc cgctcgccgt cgagccgggc ggcgagcggc
     3481 gggccgccaa gcggacccgc ggcttctagg acctgtccgg ccctggtgca tcggacggac
     3541 ccccagggcc cgtccgatgc accagggccg cgtccgctgt gttgggtgag tcgatcgccc
     3601 ctggtgcgcc gtgcgccggg ggcttcgtcc tgctcacccg tgaggggacc gtggtgttcc
     3661 tttcgggcac cgcgccgagt ggacaacaaa cgcgtttact tacgccggcc gggcctgcgg
     3721 gtcattcgac cgggcagggc gttccggcga atcaacttac gagaaatttg acgccggcgg
     3781 gtgtgctagt ttcggccatc ttgacgacga aactctgagg tcggggccgt tatcttggtc
     3841 gcgcatcgcc gtgaccgttg tcaaaacggg ggggtgtgct catggcgagg cgcgtcgcca
     3901 acacgaacca gaggagcggg gccgcgcccg gcgccggccg ggtggggagt gtcgccaagc
     3961 ggcagaccgc gctgctcggt acgggagtgg cactggggct gctgggggtc ggagccacgc
     4021 tcgcccagcc gtgggccatc ggaaaactga tcggagcggt gtccgcggga gcgtcgctga
     4081 ccggttccat catcacggtc gccgcccttt tctgcctggg tgctttcttt tccgcgctcc
     4141 agtcctacgt aatagggcgg gccggggaaa atatcgtcta tgacgtccgg cacggccttg
     4201 tcggaagatt gttgcgggcc gatctcgcgg aattcggtaa atggccgcag ggcgacatcg
     4261 tcacgcgcac ggtcaccgat acctcgctgg taaagatcgc cctctcgcag agcctcgcgc
     4321 agctggtcat cagcggcgcc acgacaatcg gctgcgtcgt gctgatgtgc accatcgacc
     4381 tgtcgctgat gctcatcacc ctggccagcc tcggcgtcgc cagcaccctc gccatcgtgc
     4441 tcgcgcgcaa gctccgcgga gcggccctgc agaaccgtga cgacaccggc gcgttcggca
     4501 gcggcgtcca gcgcgtgctc tccgcactgc ccacggtcaa ggcgtcccgg gccgagccgc
     4561 gcgagaccgc ccggatcggt gcgctggccg agcgggcgcg gcgctcgggg atccgggtca
     4621 atgcctacaa cgccctgctg gtcccctcga tgaacgtcgg cacccagggg gcactcgccg
     4681 tcgtcgtcgg cgcgggcatg gcctgggtcg cgcggggcga gatgagcatg gccgacctga
     4741 ccacgttcgt catgtacctg ttccagctgg tctcccccct ggtgatggtc ttcatggcca
     4801 tcggccagtt cgtccagggc cgggccgcca tcgagcgggt cgacaagctc gccggcctgc
     4861 cccaggaggg cggcggggcg gcggacgcgg ggcagggcct cgcaccgacc gggccgctgc
     4921 ccgcgcacca ccccgcgatc gagttccacg acgtgcgctt cggctaccgg cgcggagagc
     4981 cggcggccgt gacgcaggtg ctgcacggcg tctcgctcag cgtgccggcg cgcgggctga
     5041 cggcggtggt cgggccctcg ggcgccggca agaccaccct gttccaactg atcgaacgct
     5101 tctaccgggt ggacggcggt cgcgtgctgc tcggagggcg ggacgtcgag gggctgccgc
     5161 tggagacgct gcgcgggctg gtgggctacg tccagcagga cagcgccgcc atgcggggca
     5221 ccgtccggga gaacctcacc tacgcccaac cgcacgccag cgaggacgac atccgagaag
     5281 cgctggagat ggccggtctc ggcgccgtgg tcgccgggct cccccagggg ctggagaccg
     5341 aactcggcga ccagggcagc ggattgtccg gcggccagcg ccagcgcctg tgcatcgccc
     5401 gcacgctgct gcagaagccc gcggtcatgc tgctggacga ggccacctcc cacctcgact
     5461 ccgactcgga gcgggccttc cgcgacgtgc tgcgccgggt ctcccggcag tgcgcggtga
     5521 tcgccatcgc ccaccgcatc tccacggtga tcgacgccga gaagatcgtg gtgctggagg
     5581 acggccgggt ccgggccacc ggcgtgcacc gggacctgat ggagaacgac gcgctgtacc
     5641 ggcggctggc cggctcacaa ctgcacgccg agtccggccc cgccgccacg gcgggcgacc
     5701 gggcgcgcgg ggaaccgggg gcgggaccgc tcccgtccgc ggtcggccgg cccccgtggg
     5761 gcggcctcaa cgagcagacg gtgcggcttc ggcccatcgg gatcgaggag cagtggtgaa
     5821 cagcaccgat gtggcgatcg tcggcaccgg ccccaacggc ctggcggccg gcgtggtcct
     5881 ggcccgggcc ggcctgaggg tggagctcta cgaagcggcc gagaccatcg gcggcgggct
     5941 gcgcaccgcg tcgctcttcg acaccggcgt cgtgcacgac atctgctccg ccgtccatcc
     6001 gatggccgcc gcctccccgt tcttccgggc gttcgacctg gcggcccgtg gggtcgagct
     6061 gctgcacccc gagatcagct acgcccatcc gctggacggg ggccgtgccg ccctggcgta
     6121 ccgctcgctg gcggacacct gcgcgcacct gggccccgac ggcccgcgct ggcggcggct
     6181 gatgggcccg ctgctggagc acagcgaggc cgtcgtcgac ctgatcctct ccgggcagcg
     6241 cagcctgccg cgggaccccg ccgccgccct gctgctggcc ggccgggtgg cggtccacgg
     6301 cacccggctc ggcgcggcgt acttccaggg cgaggaggcg gcggccctgc tcaccggtgt
     6361 cgccgcgcac gcggtcggca agctgcccag tttcgcgggc ggcgcggtgg ccatgctgct
     6421 gggacacctc gcacacggga cggggtggcc gctgccgcgc gggggcagcg gccggatcgc
     6481 ggaggcgatg gcccgggaca tcgccgcgca cggcggcgtc ttccacaccg gtcacccggt
     6541 gacggacctg gcggaactcc gcggcgcgcg ggcggtgttg ctcgacacca gccccaaggg
     6601 cttcctggcc ctcgcgggcg accggctgcc gcggtcctac gcgcgcggcc tcgcgcgctt
     6661 ccgctacggt ccaggcgcgg ccaaggtcga cttcctggtc tccgagccga tcccctggtc
     6721 cgatcccgcc gtgggccgcg ccgggacggt ccatctgggc ggtacccacg ccgagatggt
     6781 ccggcaggag acgaagaacg cgcgccgggt gcggacccgg gaaccgttcg tcctcctggt
     6841 ggaccccgcg gtggccgatc cggggcgcgc gctgcccggg aagcgcccgg tgtgggcgta
     6901 cgcgcacgtg ccgaacggtg atcccaccga tccccacgcg ttggtacgcg cgcgcatcga
     6961 gcgctacgcc ccggggttcg gggacacggt cctcgcccac cgctcggtgc ccgccgcctc
     7021 gtacgagacg tacaacccca actacgtcgg cggcgacatc ggttcgggcg cgatgacgct
     7081 gtaccagagc ctggcacggc ccgtcccccg cttcgacccc taccgcaccc cgctgcccgg
     7141 ggtcttcctg tgttcctcgg ccacccctcc ggggcccagt gtgcacggca tgtccggtta
     7201 tctggcggct gtttccgcat tgcggcattg tttcaggaca tatgacatac ccgacgtggg
     7261 tccgaagtcc gcgctattga cgggtgcatg tccgcgttaa agcggcgaca actttcactt
     7321 ccgccgtcaa tcaatgccca actcttcggg tcttcccgag tcgtgcacga cggcgcggga
     7381 caaggcagga cggggtacgg cccggaacgg cggtatagac cagggtggtt ggaggcatcc
     7441 gggcccgtgg tgcggggcaa tccaggcatg cgtaggacag caatcatccg gcccggaagc
     7501 tttgcctcct tgtggtatcg cacgtattca ctggcgccca tcgcgatgta tatgatggac
     7561 tcacacgaca taacctgaag ttccccacac ttcgttgagg cgtttccact ggatcgacag
     7621 gcgctgctgg tctgaccaac catgcgcaac gactgcggtt tcacctgcgg tcgtgttggc
     7681 ctatgacgtc cttccttgct ccggctcttc ggcttcacgg cggcccccta gggatcgaat
     7741 gtggggacaa agtgagggag ttcggtgact aacggggttg aagacatcgg ctatgggcga
     7801 cagttcgccg gctggtacga caggctgata ccggacgacg aagtcaccgc cgaggcggtg
     7861 aaggggctac tggccctcca tcccgcccct gaggcgggga cgatcgaact cggcgtcggc
     7921 acggggcgga tcgccgtccc gctttccgag agcgtcggca gggtgaccgg tgtggactcc
     7981 tcaccggaga tgctggacgc gatgcgcgtc aaactgaagg agcgtggaga cgtcaccccc
     8041 gtccacggtg acatccgcag ctatacctcg gattcccgtt acgggctggt gtattgcgtc
     8101 tgtgcgacgc tgtcgctgct gcacaccccc gaggaccagc tactggccgt ccggcgcgcg
     8161 gccgaccttc tcgcccccgg cggcaggctg gtgatcgaga cgcacaacaa gccgccgatc
     8221 ctggagctcc acgaggggcg caagcgcacc acgtatttcg tcccctatcc ggagcccggc
     8281 acgggcgtgc agacccattc gacgctgctc gacggcgacc tctggcactg ctcgcacatt
     8341 ctgtaccagg ccgacggcac cacccgggtg ggcagcgaac tcacccggct gaccaccccc
     8401 gaagagatcg acgcatacgc ccgcgcggcc ggcttggagc ccgagaccca cctttctcgg
     8461 tgggacggca ccccctataa cgaacagtca cccatgttcg tctgctgcta cgtcaagtcc
     8521 tgagcgcaca caggaaagcg gaacacagaa gggggccaca ggtgggacga ccgccgattt
     8581 tgccggcaga caagaaactc gggctcctgg tgcgagtgat gagtggtcaa ctgaccgcgg
     8641 ccgaagcggc acgggaagtc ggagtctccg agcaatccgt atcgaactgg cgcagacagt
     8701 ttattgaggg agcccgtaac ggcctggccg gcgagagtgg aaaggactcc gaagaggcgt
     8761 ccaggatcgc cgagctcact caggaaaacg cgatgctcaa ggccacaata ggcgagctgt
     8821 atatggagct ccggaagtcc gggcggggca cacccggcca cgttccgcag ccctgcggga
     8881 agacacgccc ggcccggcgg gtcaactaac tcattatttg accccggcat ccggtgttag
     8941 tgtcggggat atcagccact tgaaatcacg ggggagggat tgtggcgtct ttggagcgcc
     9001 aattcgccgt gggcatagct ggtttggccg gtgcgagcct gctgaccggt gcggtaatgc
     9061 gattcacggg gaaacgcgaa cgtgcgcgtc gctacctgat gcacgagagg ccggacggca
     9121 gcctcgtgga ggtcgacgtc agcattcctt ctcaggctcg gcgcgtcgtc ctgctcgaca
     9181 acgggctggg cgcgccgcac gaatactggg actgggtgtg cgacgcgctt cccgcggaca
     9241 tggggtacgt gcggttcaat cgccccggct acggactcag cacacccgtt gcccagtacg
     9301 gtctgcaccg gcactacgcg ctgttgcagg aattgcgtga cacctatgtc cccggtctcc
     9361 cggtcgtcct ggccggccat tccctgggcg ggtacttcgt cgcggcctat gcctcgcgcc
     9421 atccgggcgc gctggagggc gtgagcgcgg tggtcatgat cgacgccacc gaggtgacca
     9481 gcctgcgcca ctcgcgccgc accgacatcg accggtgggc gcgccagtcg ctggtgatgg
     9541 agcaggcgta cgcctgggcg ggcctgtcgg ccttccgccc ggccaagaac gtgaaccagc
     9601 agtaccgtcc ggagatcaac cgcagctaca ccgcgttcct gacgaacccc cgctcctggg
     9661 ccacggccca ccgggagtac cgggacgcca tgacgtaccc ggaactgacc gacctggact
     9721 gcccgttgac cgtggtcacg gcggagaaca acgtcggcga caacaccatg caccacgccg
     9781 tccaggcccg cttggccgcc atctcgaagc ggtcccggca ccacttcatc gagggctcgg
     9841 accacgaatc cgcgctcgcc gtgccggacc acgcccgaca ggtggcggag gtgatcgcgg
     9901 gcgaaccgcc caccgggcgg accggcccgg agcggcggca gaccgccacg aaggaccggc
     9961 cggccgcggt gcgcgacacg gagcgggagg aggaactgac gtgaacgtga acacggaacg
    10021 cctgaaaacg gccgtcgtca cggcctcgat cgccgcctgg ctggtggcga cggcggccgg
    10081 gcagctgccc gagaaccgct tcgacaacct cctgcggcgc gggcggtggc agatcccggt
    10141 ccccaactgg cgcttcttcg gcccgaaccc cggggtcaag gacaaccacc tgctctaccg
    10201 ggacatcacc gacggcaggc ccggcgactg gacggaggtg gagatcaccc gcgaccggcc
    10261 ctggtacgcc ctggtctgga acgcccgcaa ccgttgcccc aaggccctgt tcgacgcgag
    10321 ccaggacacc atctcccgct cggtggcctt cgggccggaa ctccgcctgg tgacactggg
    10381 ctccggatac cagctgctct cccgctacat ccagcgccac ctgccgcacg ccgagggcgc
    10441 ctcgcacagc cagttcatgc tgatgcagtc gtacctcaac gcccccggcg accggcagat
    10501 caaccccgtc ttcgtctccg tggaattccc gctgaccgaa gacgccacgc ctgacgcggc
    10561 cgcattcccg ctggccgcgt agcgagccga tcaaccttct cggccggaag ctgcgagctc
    10621 actcggttcc cctgtgccgc gtgagttcgc gccctcccgc cgaacggctg gagaactcgc
    10681 tgtgagatgt ctacgagaaa gaggacagaa atgtctgttg tggctgaatt cgccaacacg
    10741 cagctggtgg acgtgaagcc gggccgtatc ggttccgacg ccgcgccgac catgatgacc
    10801 ccgctggcca ccgtcgcgac ccccgaggcc gtgtccgccg gcatcgcggt gacctccgcg
    10861 accgcggccg cgctgaacat ggtcacccac aacgtccagc acggctgagc gttcggctgc
    10921 ggggcggtgc tgaccggcat cgataacccc ggccgatgaa agacgcggcg gcacggtacg
    10981 cccgatacgc ataccgtgcc gccgtttccc atatccacta tccaccgtac tcgcatcaca
    11041 tcatcaggag cacccatcca tgttcctcag cgctccgccc gaggtcacgg cacgccgagt
    11101 ggcttcgctg ggtacgcttg tctccgcact ggaaatgctc agccagacgc gtaagttcga
    11161 agacggtgaa ttgctgagcg gccagctcgc gaacatgcga cccaagttcg ccaagcgatt
    11221 tccccgcctg acccgcgccc tgagttccaa gaaggcggcg gtcgccctgt acggagtgca
    11281 ggcgggtgct tctgccgcca cgctgatctg ggggcacaag cgcgcggtcc gcacgacggg
    11341 cagcgcggtc ctggcggtga cgggcgccgc cggccggctg cacaccccct tcggcggcga
    11401 cggtgccgac cagctccagc aggtggtcaa cgtcgtcctc gcctcgaccg gcaccttcaa
    11461 ggacggcgag aaggcccgcg acgtggccat gcgcgcgctg gccctggaga cgaccatctc
    11521 ctacgtcgca tccggtgtgg tcaagctcgt ctccccggtg tggctcagcg gcgaggcgtt
    11581 cagcggggtc atccgtacgc acaactacgg ggacccgcac ctctttcaac tggtgcacaa
    11641 atacccgctg ttggggaagc tcatcacctg gggaacggtc gccgcggagg tcggcttccc
    11701 gctggtcttc gtgctgccca agccggcggc cagggcatgg ctcggctcga tgagcctctt
    11761 ccacctgggc atcgggcagt tcatgggcct caaccgcttt gtgctggcct tcggcgccac
    11821 gcacccggcg atcctctatg tcctcgaccg gagcgagggg cgtgcggcgc tgacggggag
    11881 gacctccgcg gccgtgacgt cggcccccgc ggccgcctga gcgagcacag gtacggccat
    11941 cggcatgagg catgcccgcc cgacgggctc cctttgccgt tcgcgaagca catccccgca
    12001 gtggccggat gcattcccgg acagggcgat gaattcccct gcagggtccc gactttcaaa
    12061 ggagacgcaa tcatgaagcg catcaccatg gccgcgggcg tcgcggtggc gggcgccatg
    12121 ctcgccgtgt ccgcccaggc cggcgcgcag gccgcgccgc tgccgcggac gaccgtggcg
    12181 gacgccgcgg ccgtcacgcc ctcggcggcg cagggcgact ggaacccgcc ggccggctac
    12241 accctggagc gctcgttcct gggtgacagc gcctcctgca gtaaggaagg ggacgcgggg
    12301 gtggccgcgg ggaagtggca tcaatacgtc tgtcacgagc agatgatgaa gctcaccgac
    12361 acctggatgc tcttccagtt cctctacgtc aagaagtaga agaagagaag aaggagaaga
    12421 agcgggtcgc ggaccccgcg acacgtacga cgggcggccc ccagatgggt gccgcccgtt
    12481 cgcgtacgaa aatcagagcg cgccgacggg cgtgcggggc ccctgagaac cccgtccgcc
    12541 gccggatccg ctccgccggt cgggtcagtg cccgccgtgc gcctcgaagc gcttgtacga
    12601 gcgctcgatc tcggcctcgg cgtcggtacg gccgacccag ttggcgccct cgacggactt
    12661 gccgggctcc aggtccttgt agacctcgaa gaagtgctgg atctccaggc ggtcgaactc
    12721 cgagacgtgg tggatgtcgc ggaggtgctc cacgcgcggg tccgaggcgg gcacgcacag
    12781 cagcttgtcg tcgccgccgg cctcgtccgt catccggaac atgccgatgg cacggcactt
    12841 gatcaggcaa ccggggaagg tcggctcgtc caggatgacc agcgcgtcca gcgggtcgcc
    12901 gtcctcgccg agggtgttct cgacgaagcc gtagtcggcc gggtagctgg tcgaggtgaa
    12961 gagtcgacgg tccaggcgga tccgaccggt ctcgtggtcc acctcgtact tgttccgcga
    13021 acccttcggg atctcgatgg tgacgtcgaa ctccacgggt ggctcctcca tgatcaacac
    13081 atacgtctgg tgattaagtg tcccccacgc aggtgtgtgg tggcgaaagg ggctggtccg
    13141 aagtgcccga gacccgaaca tggcaggtca catggcagtc ggcgcagcgt tccgcgcggg
    13201 tggcggcacg ccgggcgggg cgttccgcac gcaccgcagc acggaccgca cagcgcgccg
    13261 cgcatgcgac aacgggcgcc gcacagcacg catggcaggc cgcaccgcgg caaacgcggc
    13321 agacctggca gctgacagcg gcgtccgccg ccacaggtct ggcggtcgcg gtcgtcgcgg
    13381 tggcggcggc cgggccgtgg gactccggtc agcgtacggc cgagcgggcg gcggcggtcc
    13441 ccgctccggc aacaggtggc gagcatcacg atgacggccg ggcgcccggc cctgcgccca
    13501 gcgcgccggc ggtgctgacc gcgctcggcg ggcccgcgcg cggcgcggtg ggccgcggcg
    13561 gcgcggcgcc ggcgcccacc gacgccggac tggccgacgc cctgtccccg ctcctgtcgg
    13621 accccgcgct cggcccgctg cggaccgcgt ccgtggtgga cgtcgcggcc ggccggcagg
    13681 tcttcggcga gaagcaggac gaggcggcca cccccgcctc cacggtcaag ctcgccaccg
    13741 ccgtggccgc gctctcccgg ctcggtgccg accaccgcat cgacaccggc gtcgtgctgg
    13801 ccggcaagga ccgtatcgtc ctggtcggcg gcggcgaccc gaccctgacc gcccgtgcgg
    13861 ccggcccggg gcccgacgaa cggccggcca gcctgcgcga cctcgccgac gccaccgccc
    13921 acgccctcca gcagcgcaag ctgaccaccg tcggcctcgg ctacgacgcc tccgcctaca
    13981 cgggccccgc cgagcacccc atcggcccca acgagaacat cgccccggtc gccgccctga
    14041 tgaccgacga ggcccgcctc gacgacagcg accacggcac cgcaccgcgc tccaccgacc
    14101 ccgccggcga cgccgcccgc accttcgccg gcctcctcaa ggaacgcggc atcaccgtca
    14161 ccggcgaccc cgccgaggcc cgcgccccga aaagccccga ccggatcgcc gtcgtccgtt
    14221 ccctgccgct ctccgccctc gtcgagcgga tgctgaccta cagcgacaac gacatcgccg
    14281 aggcgctggc ccggcagacc gccctcgccg cccaccagcc ggccagcttc gacggcgccg
    14341 ccaaggccgt gcgggacgcg ctggccgccc agcacctccc gctgaccgac gccgtcttcg
    14401 aggacggcag cggcctggac cgggacgaca aggtctccgc gaacctgctc tcccgcctcc
    14461 tgctggccgc cgccgcaccc gacaagcccg aactccgccc ggtcctcacc ggcctcccgg
    14521 tggccgcctt caccggcacc ctcagggggc gctacgtggg cgacaccgcc ggcgccggca
    14581 ccgtgcgcgc caagaccggc accctcaccg gcgtcaacag cctcgccggc accgtcgtcg
    14641 acgccgacgg ccgcctcctg gccttcgcct tcatgaccac cggcaccacc gacccccagg
    14701 ccgcccagaa ggccctggac cgcatggcct ccacggtggc caactgcggc tgccgctgaa
    14761 cgacccaccc tccgggcgcc cacccaccgt cctcttcacc cgcgcagcgg ccacgcgggg
    14821 ccgaccaccc ccgtcggcta ccagccggcg cggcgtcccc gtaccgtgaa cccatgacga
    14881 gcatcggtgg tgtcgagatg gtcgactgga atctcgcggt cgcgaccgcg acccgattcg
    14941 tacggcccgg tccggaggtg agccgggacg aggcgcgggc gatcgtcgcc gagctgcgcc
    15001 ggcacgccaa gtcgtccgag gagcacgtcc gggggttcac ccgaatggcg caacccggcg
    15061 cggagggcgg ggcggtgtcg cacgacacgc cggtcctggt ggtggaccgg cccggctgga
    15121 tccgggccaa cgtcgccggt ttccgggcgg tgctcaaacc gctgctcgcc aagatggagg
    15181 accggcggtc ctcgacgccc ggcggtgcgg tgctcggcgc ggtcggcggc aaggtgaccg
    15241 gcgtggaact gggcatgctg ctgtcgttcc tggcgtcgcg ggtgctgggc cagtacgaga
    15301 cgttcgcccc ggcctcgcgg gacctgccgg ccgggacgca gggcggccgg ctgctgttgg
    15361 tggcgccgaa catcgtccat gtggagcggg agctcgacgt ggcgccgcac gacttccggc
    15421 tgtgggtgtg cctgcacgag gagacccacc ggacccagtt cagcgccgtg ccctggctgc
    15481 gggaccacat cgagggcgag atccagtcgt tcctcagcga gaccgacatc gacccgggga
    15541 cgctgctgga gcggctgcgg gaggccgccc agtcgctggc cggcgccaag ccggagggcg
    15601 aggagggcga ggagagccgg tcgctggtgg acgtggtgca gacgcccgtg cagcgggaga
    15661 tcctcgggcg gctgaccgcg gtgatgtcgc tgctggaggg gcacgccgac tacgtcatgg
    15721 acggggtggg gcccgaggtg gtgccctcgg tggcggagat ccgggagaag ttccagaagc
    15781 ggcgggccag cggcgccggc cggctggacc aggcgctgcg gaagctgctg gggctggacg
    15841 cgaaactgcg gcagtaccgt gacggtgagc ggttcgtgcg gtccgtcgtc gaggaggtcg
    15901 gcatggacgg cttcaaccgc gtctggacgt cgcccaacac cctccccacc aaacaggaga
    15961 tcgccaaacc ggcggactgg gtcgcgcggg tgcaccggaa ggccgacgga gcacagtaag
    16021 cccaggatgt gagccgggca cgccatgcgg cagtagagcg ccccttcaat cacccgtctg
    16081 agggaccgtg accgatggat aggcgtgcaa tgctcgggga actgctcgcc tctgtcacca
    16141 tctaggcact ctctgttacg aagtgccgtc catgcttgag gctcgccccc agctgaacga
    16201 ttggaaacgg acatgggtcc ccatccagcg gtcgccgcga tacgcctggc ggtccgccgc
    16261 gtactccacg acgtgctcac ccaccactgc gcgcaggacc ggcgcgaggc accgctcgtg
    16321 ctcgtcgcct gctccggcgg cgccgactcc atggcgctcg cctccgccct cgccttcgaa
    16381 gcccccaaac tgggcgtccg cgccgggggc gtgaccatcg accacggcct acaggagggc
    16441 tccgacctcc gcgccgccga ggtcgccctg cggctgcggg ccctcaagct cgaccccgtc
    16501 gacatcgtca gcgtcgaggt gggccgggtc ggcggtcccg aagcggccgc ccgcgatgcc
    16561 cgctacgccg ccctggacgc caccgccgac cgccacggcg ccagcgcgat cctcctcggc
    16621 cacacccgcg acgaccaggc ggagaccgtg ctcctcgggc tggcccgcgg ctccgggatc
    16681 cgctcgctct ccgggatggc cgcggccacc gggacgaacg gccgctaccg ccgccccttc
    16741 ctggacgtgg accgacagac cgcccgtacg gcatgcctca tccaggcgct gcccgtctgg
    16801 gacgatcccc acaacaccga ccccgcctac acccgctcac ggctgcggca cgaggggctg
    16861 cccgccctgg agaagtgcct gggcaagggc gtcgtcgagg cgctggcgcg gaccgcccag
    16921 ctctcccgcg acgacgccga cgcactggac ggctgggccg cagacgccga ggtgacggtg
    16981 ctcgacgagg ccggcaccct cgacgtggcc ggactcttcg cgctgccggc cgcggtgcgc
    17041 cgtcgggtgc tgcgccgggc ggtcatcgcg gccggttcgc cggccggttc gctcttcgcc
    17101 cgccacatcg aggaagtgga ccggctgatc acggcctgga gggggcaggg tgccatcaac
    17161 ctccccgggc gcgtgggtgt gcgacggcag ggtggcagac tggtcattcg gcagggctga
    17221 gcggcagaga tcgcgccctg ccctgtgatc tcacgaccgg ttcccgcttc gtgagctcca
    17281 cgaccgatct gcacacgtaa ccgaacgaga gtggcacggg tggacgacaa ggacatgggc
    17341 gccgaccttc agtcggtgct catcactaag gaagagatcg acgccaagct ggctgagctg
    17401 gctgcgaaga tcgacgcgga gtacgcgggc aaggacctgc tcatcgtcgg tgtcctcaag
    17461 ggcgcggtga tggtgatggc ggacctggcg cgtgcgctgt ccaaccccgt cacgatggac
    17521 tggatggccg tgtcctccta cggcgcgggc acccagtcct ccggtgtggt ccgcatcctc
    17581 aaggacctgg acaccgacat caagggcaag cacgtcctga tcgtcgagga catcatcgac
    17641 tcgggtctga cgctgtcgtg gctgctgtcg aacctcggct cgcgcgagcc cgcctcgctg
    17701 gaggtctgca cgctgctgcg caagccggac gcggccaagg tcgccatcga cgtgaagtgg
    17761 atcggcttcg acatccccaa cgaattcgtc gtgggttacg gcctggactt tgcggagaag
    17821 taccgcaatc tgccgttcgt cggtaccctc tcgccccacg tgtacggcgg ctgagagcac
    17881 ccccgcgtct cccggccgcc gcgtcggacg gggacccgga tggcccgtgg cgggcggcgg
    17941 gaacccttcg gggattcccg ccgttggagc agggagaggg gaatcccggg cttcattgtt
    18001 ccgcaccggc acaggcgccg ggtgacaatg ctggggtacc gtccgaaggc agtcggtttt
    18061 cgggccagta atacacaccg tacgcacgac cagccctcca gagggcgttg tgcctcactg
    18121 tggcaggagg gacggggcct taggtggctc cgtgtggatg gacgtgaagc gatacttccg
    18181 tgggccggtc atgtggatcg tgctggccgt cctcgccgtg gtcgtgttga tgcaggtcgt
    18241 cggctcgtcc ggcggctata agacggtgga caccggtcag gtcgtcaagg cgattgctga
    18301 caacaaggtg aagtccgccg agctgaccac cggcgacgag aacaagatca agatcgagct
    18361 gtcgggcgac aacaagatcg ccggctccaa caagattcag gccagctaca tcggcgacca
    18421 gggcgttgac ctggcgaaga acctgcaggc caagtaccag acgggcgaga tcaaggacgg
    18481 ctacaccgtc tccccgtcga agcagaaccc gttcgtcagc gtgatcatca cgctgctccc
    18541 cttcatcctc atcccggtca tcttcctgat cctgatgaac cagatgcagg gcggcgggtc
    18601 cagggtgatg aacttcggca agtcgaaggc gaagctgatc accaaggaca cccccaagac
    18661 gaccttcgcg gacgtcgcgg gtgccgatga ggccgtcgag gagctccacg agatcaagga
    18721 gttcctccag gagccggcga agttccaggc cgtcggcgcc aagatcccca agggcgtgct
    18781 gctgtacggc ccgcccggta cgggcaagac gctgctcgcg cgcgccgtgg cgggcgaggc
    18841 cggcgtcccg ttctactcga tctccggctc cgacttcgtc gagatgttcg tcggtgtcgg
    18901 tgcctcccgg gtccgtgacc tcttcgagca ggccaaggcg aacgccccgg cgatcgtctt
    18961 cgtcgacgag atcgacgccg tcggccggca ccgcggtgcg ggtctcggcg gtggccacga
    19021 cgagcgcgag cagacgctca accagctgct cgtcgagatg gacggcttcg acgtgaaggg
    19081 cggcgtgatc ctgatcgccg ccaccaaccg cccggacatc ctcgacccgg cgctgctgcg
    19141 ccccggccgt ttcgaccggc agatcgccgt cgatcgtccg gacctgcagg gccggctgga
    19201 gatcctcaag gtccaccaga agggcaagcc ggtcgcgccg gacgtcgacc tctcggccgt
    19261 cgccaagcgc acccccggct tcaccggtgc cgatctgtcc aacgtcctga acgaggccgc
    19321 cctgctgacg gcccgcagcg acaagaagct gatcgacaac cacttcctgg acgaggcgat
    19381 cgaccgcgtc gtggccggtc cgcagaagcg gacccggatc atgtccgaga aggagaagaa
    19441 gatcaccgcg taccacgagg gcggacacgc cctggtcgcg gcggcttcgc cgaactccga
    19501 cccggtccac aagatcacga tcctgtcccg cggtcgggct ctgggctaca ccatggtcct
    19561 gcccgacgag gacaagtact ccaccacccg caacgagatg ctcgaccagc tggcgtacat
    19621 gctgggcggg cgtgcggcgg aggagctggt cttccacgac ccgaccaccg gtgccgccaa
    19681 cgacatcgag aaggcgaccg ccaccgcccg cgcgatggtc acgcagtacg gcatgaccga
    19741 gcggctcggc gcgatcaagt tcggcacgga caactccgag ccgttcctgg gtcgtgagat
    19801 ggcgcaccag cgcgactact ccgaggaggt cgccgcgctg gtcgacgagg aagtcaagaa
    19861 gctcatcgag accgcgcaca acgaggcgtg ggagatcctg gtcgagaacc gcgacgtgct
    19921 cgacaacctc gttctggagc tcctggagaa ggagaccctg aacaaggagc agatcgccga
    19981 ggtcttcaag cacatcgtga agcgcccggc ccgcccggcg tggaccggct cctcgcgccg
    20041 tacgccctcg acccgtccgc cggtgctgac gcccaaggag ctggccccgg ccaacggctc
    20101 cgcggcatcg tcggtctcca tggagaagac ggacacctcc gaggaaccgc gctcggagag
    20161 ctgagccagg ggcccccggg ccccggaata cgcgccgcgc cccccgaggt tttagcctgg
    20221 ggggcgcggc tttccgcgtt tcgagcgggc ccagaaggaa cgaggcacca atgacggacc
    20281 ctgtgacgct ggacgtcgag ggcgcgatcg gcacgtttga cgagaagcgt gcccagaacg
    20341 ccgtgcgcga gctgctcatc gcggtgggcg aggatccgga ccgcgagggc ctgctggaga
    20401 cgccggcgcg ggtggcgcgg gcgtacaagg agctcttcgc tggcttgtgg cagaagcccg
    20461 aagacgtgct gaccaccacc ttcgatctcg gccatgacga aatggtgctg gtcaaggaca
    20521 tcgaggtggt ctcgaactgc gagcaccacc tggtgccgtt cgtcggtgtg gcccacgtcg
    20581 gctacatccc gtccaccgac ggcaagatca ccgggctgtc caagctggcc cggctggtcg
    20641 acgtgttcgc ccggcgcccc caggtgcagg agcggctgac cacccagatc gccgaatcgc
    20701 tgatgcagat tctggagccg cgcggggtga tcgtggtcat cgagtgcgag cacatgtgca
    20761 tgaccatgcg cggggtgcgc aagccggggg cgaagacgac gacctccgcg gtgcgcgggc
    20821 agctgcgcga tcccgcgacg cgggccgagg cgatgagcct gatactggcc cgctgaggcc
    20881 gggcggccgg gcggccggga gaagacgg
//
