LOCUS       NZ_CP054019            24466 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. A1-5 chromosome.
ACCESSION   NZ_CP054019
VERSION     NZ_CP054019.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. A1-5
  ORGANISM  Streptomyces sp. A1-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9459690)
  AUTHORS   Dashti,Y., Sumang,F.A.M., de los Santos,E.L.C., Alcantara,E.P. and
            Challis,G.L.
  TITLE     Structural revision and biosynthesis of polyketides FXJ15321 and
            FXJ15322 from Streptomyces sp. A1-5
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9459690)
  AUTHORS   de los Santos,E.L.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2020) Warwick Integrative Synthetic Biology
            Centre, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL,
            United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUN-2019
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:28:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,328
            CDSs (total)                      :: 8,230
            Genes (coding)                    :: 7,847
            CDSs (with protein)               :: 7,847
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 383
            CDSs (without protein)            :: 383
            Pseudo Genes (ambiguous residues) :: 0 of 383
            Pseudo Genes (frameshifted)       :: 156 of 383
            Pseudo Genes (incomplete)         :: 280 of 383
            Pseudo Genes (internal stop)      :: 26 of 383
            Pseudo Genes (multiple problems)  :: 73 of 383
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:08:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3562240
            Orig. end                         :: 3586706
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Philippine National
            Collection of Microorganisms.
FEATURES             Location/Qualifiers
     region          1..24466
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="15"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24466
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24466
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14466](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14466)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(1504..1518)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            2158..3864
                     /locus_tag="HRD51_RS15915"
                     /old_locus_tag="HRD51_15655"
     CDS             2158..3864
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016763.4"
                     /locus_tag="HRD51_RS15915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15655"
                     /product="VanZ family protein"
                     /protein_id="WP_235093362.1"
                     /transl_table=11
                     /translation="MNSTYLLPIRTAALLFPALALLMFVPTAIVLYRRHGVLTRWRALS
                     LYGGVYYALTAFCMTIVPLPKPSVDVCTAYPAFAHPQLTPGVALTDIWKEAHHHATLDA
                     LVLHNPAFWSNTFNVLLLLPLGVFVRIHFRRGLTAATAAGFTTSLFFELTQYTGLWGLY
                     ACPYRLFDVDDLIANTAGAALGWAVAGPLARALPELDTLDDRALASGKVPFGRRLVALI
                     LDTTGVTLLSWLIGALTYRELGEGTLLCAPPSAFALWFVVIPWLTGATPGKHVLLLRLV
                     TPDGGRPSPARLALRALVLSPPLVLACLAAGAVLAIAADPSLLIKIADEVVHRTLSADP
                     ASAFVLLLPPAACLTLIAAYVKSVRRHPQGLGPHETRSGIRNHALPHTRARTPATPATP
                     PNPADPHVRSLPRRQLRTDRNPGSAESGRVAAPSPRPRPSFFRAARWVGACGLRGCVRR
                     FGCGSGRVRPESEGFSQSSRMRGGRFSGVPGTVPALQSAAGMGMGGASQPRIRGSGCLW
                     PVKTGSTNEHYRAQVVLAWQSLLPGQVLVRGQVLVPGRRLVPGRSLLSFSW"
     gene            3869..5080
                     /locus_tag="HRD51_RS15920"
                     /old_locus_tag="HRD51_15660"
     CDS             3869..5080
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="HRD51_RS15920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15660"
                     /product="histidine kinase"
                     /protein_id="WP_235093363.1"
                     /transl_table=11
                     /translation="MRGDGGSRRAALVVDGVVIAAAAAELLTLYDALDALSALVCPPSL
                     FALVLRRRFPVAVLFATLPSMATGHLWLAPMIAMFTVASRTARRAVVGVATAALFAATM
                     WSGYDLDGGAVDWSHHLFVVEVALMFSVGPAGLGLLFRTRSELRARLADLIASQAHGRR
                     LEAERAVAEERTRMAREMHDSVSYHLGIIAAQSGALWATAPDDTVRRDAESIRRHSADA
                     MAELREIVGVLRHGPSRADGTDARLRNVPTLVAEARLDATLDCGALETHTLAPSVERAA
                     YRTVQEALTNVRKHAPGAPVAASVRPSARGDTLVVEVRNQPAPRTPPPVAPVLDVPASG
                     YGLAGLRERVTLVGGAFRAEATADGGFVVRAELPLGTAAPVASGPASGHQPATAAQGES
                     GSRS"
     gene            complement(5035..5799)
                     /locus_tag="HRD51_RS15925"
                     /old_locus_tag="HRD51_15665"
     CDS             complement(5035..5799)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980774.1"
                     /locus_tag="HRD51_RS15925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15665"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_235093364.1"
                     /transl_table=11
                     /translation="MALGNALYDQKLASVYDRMYPIDHDTAQAVEFVAGRTPPDGRILE
                     LGVGTGRIAVPLAGRGFRVHGIDGSEAMLDELHRQNPQTAVTTQFGDFTEEGTGGVFDT
                     VTLLLNTFFVAITKEQQLGTLRLVREQLAPEGRFVLEAFDPAPYHHLEKPDFSMRHLDE
                     QTVMLDTLAVDRSQQLMLSTHTIIDGGAPATREHVLRYAFPFEIDLLAELSGLRLVERT
                     EDWCGTPYTSASLRHVSVYERDPDSPWAAVAG"
     misc_feature    complement(5799..5815)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.47"
                     /tool="antismash"
     gene            complement(5879..6556)
                     /locus_tag="HRD51_RS15930"
                     /old_locus_tag="HRD51_15670"
     CDS             complement(5879..6556)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005474551.1"
                     /locus_tag="HRD51_RS15930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15670"
                     /product="response regulator transcription factor"
                     /protein_id="WP_205365071.1"
                     /transl_table=11
                     /translation="MIRVMIVDDEILLRSCMQRILESEADIEVPVACDGREVREAVAAH
                     RPDVVLLDLRMPEVDGLTALEWIRAHQDPPAVAVLTTFLRDEDIAAALRSGAAGFLLKD
                     ATPQELADAVRVLASGGTVLSPAAARIVVDGYLGAGPRHGERDPRLDTLTEREQQVLEL
                     LGEGLTNADIGRRLLLSASTAKEHVSSILTKLGLANRVQAAVAAHRAAAEGHLRPSALA
                     ETR"
     misc_feature    6655..6669
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 21.31"
                     /tool="antismash"
     misc_feature    complement(6657..6668)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.4"
                     /tool="antismash"
     gene            complement(6690..7091)
                     /locus_tag="HRD51_RS15935"
                     /old_locus_tag="HRD51_15675"
     CDS             complement(6690..7091)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS15935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_15675"
                     /product="hypothetical protein"
                     /protein_id="WP_159030889.1"
                     /transl_table=11
                     /translation="MLLEFVLFSLMDTVFWIGGKSLDRARSARRIAAFRRGERITLRCR
                     FRIRAQGPAMHRGRIVVSASGVVLDGPGPRALALSGPAAAATGGGRFGTALDCTVTAED
                     GSAKKIELLVSTWDAKLVELITEHLSEPV"
     misc_feature    7089..7107
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.54"
                     /tool="antismash"
     gene            complement(7145..8137)
                     /locus_tag="HRD51_RS15940"
                     /old_locus_tag="HRD51_15680"
     CDS             complement(7145..8137)
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980837.1"
                     /locus_tag="HRD51_RS15940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15680"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_235093365.1"
                     /transl_table=11
                     /translation="MTRTPPLSLMYPLMAYDLDHLTAFGEVVRELSLERLYMGQSVLVD
                     THHAFAHLAGRGIRVPVGTSVALTALRHPLDAAIQARSLALLTGADVVAGYSTGDPAFV
                     TALRGAPYDSPRTAVAEYLTVVRRLLDGELVDFQGRYVRVDEGLPQVPHPPVSLGVGVL
                     RPRMAYTAGQVADVAITLLTPATYLRDRIVPALARGAASRDRAAPGVTSIVPCAVRRPG
                     RDPRRLAFAAHELHLGGEHYAAMLRSAGLGVDAADPWAGAGALVEGGVFAYGTPDELAD
                     RLTGYGEAGATEIALSCAGVLLTEGLDAALADVRAIVGAMQDRAVPPGR"
     gene            complement(8161..10008)
                     /locus_tag="HRD51_RS15945"
                     /old_locus_tag="HRD51_15685"
     CDS             complement(8161..10008)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008741466.1"
                     /locus_tag="HRD51_RS15945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15685"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_205365075.1"
                     /transl_table=11
                     /translation="MTDQEARDQAVPEEHRRLSRDLRYWWLVLRTFWGLSPLRVSALAV
                     ATVLTAAVPATGIWLTAGAVQAVVDALARVPDAMDRLTWAAAGLVAVAVAEHVLTSFSQ
                     YLNSLLQLEFTAKIGERVMVKGTRMDLSAYEDPEAYDRLQRALRESGSGTAFEVFEEMM
                     RTLTALASLVMVSWVLFSWNVWIALAILLAPLPALAAHVVFSKQGYAIEYHRAQDRRRA
                     FYYQDLTTTDASYKEVKLYQLGPHLVGRYRSLVQEFFRVDRALARRRHGWSAALGLVSV
                     GCSAGALVFALRSTADNGRIGELAGYLQALGAVHAAATGLLLGVATLYQNTLFTGNLFD
                     YLTLPDGRITGGTRPFPRRLTHGIEFQDVTFRYPGTTTTALDRFSCFIPADTCCAIVGA
                     NGAGKSTIVKLLSRLYEPTSGRILVDGVPLEEYDTDDLQRNIGVVFQDFIRYEMPVRHN
                     IGFGRLEHLDDDARLRAAAGSSGAAEFIDRLTDTYDTTLGRHFEGGHQLSGGQWQKIAL
                     ARAFLRDAPIAILDEPTAAIDAEAEADIFGRLRTICSRATSLVISHRFSTVRIADKILV
                     VEGGSLIEEGTHEELLAHGGTYAHLFRLQADAYLPGASA"
     gene            complement(10001..13216)
                     /locus_tag="HRD51_RS15950"
                     /old_locus_tag="HRD51_15690"
     CDS             complement(10001..13216)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009327746.1"
                     /locus_tag="HRD51_RS15950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15690"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_235093366.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-157,
                     bitscore: 524.5, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.9e-14,
                     bitscore: 52.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.9e-29, bitscore:
                     100.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAIDAIDKDLTRPMPRYEALDFPLLRAPALPVEVWRETLADRDP
                     ARTRARLRAMADDPRVRHGLVAAGSGLLDGLAKVEAAQGRASGKEMRRVHSRALRYLTR
                     MSTRPTPFGAFSGVALGSFGETTTARLGETPLVSARVRADMGWLLALVKDLEGAPEVLG
                     RLSVSMNAMAHRVGDRLVLPSSDVHGNADRRSVRVRHTSPLSHIRRLAPAAAPVPYAEV
                     VAELTDRFPAVGHERISAFVAELVGLGLLVTDLRPPVTDPCPEAYVLARLTAAGVEHPA
                     VAGLREVVDLTRTAVHDDTGALDRLRLTQRTLVPAYRHQPFQVDSALGLVDTALNRQVA
                     DEVAEAVGCLARLGRAAPGGYDHLVPYHEAFMERYGSDALVPVLELLSAERGLDAPNSY
                     LNPPRAMVMHQTGGEGDPRTARALVALASQAWRSGADEVELSDEALRRLVPADEGDTRR
                     GCPGVDAYVQIAASSARAIDDGDWRAVLNSDGLGEGGRTFGRFFHLLGPSAAERLRSYA
                     RAREALEPDVVVAELAYLPGNGRGANVAIRPAVHGYEIPVNVAPSAAPDRIIDLSDIHV
                     GATDDGLRLYSARLGRELVVVQNHMLSPLGAPNVCRFLLEVSRARYAIPTGFTWGPVEG
                     APYLPRVVRGRVVVRAAEWNLYPAGAQAPLDTAPVPVPRTAAELTEWRRTWGVPRHVYL
                     ADDDNRLLLDLDHPACADELLTDLRAADERVTLQEALPDPDRTWLRDSAGRGHLAEVVI
                     PLLAAPAGTEAAPPPDTASARAAAAEGIRRKARPAAHPSHLPGSEWSYLKLYAARDLHD
                     EIAAVELAGLAQEIRDAGADVDRWFYIRYADPDAHLRIRTRTPAGGTSALEPLLDWGRS
                     LVRRGIAERLEVATYHPEVSRYGGPAVYDHIEEFFAANSAVSVQLLGLLWDKEPGLTAE
                     AVTLAAVDALYAQWGLDVRERLAAMPRPAEDKGAREQYKKDRDYLCELLAPWDRRPHLR
                     GRAHHERLAPVLAGQADAVRRASRAVADAEAAGTLWGTRDAVLASLAHMQVNRLLPMDR
                     PAEDRCYLVWGHVLNCLRGRPRD"
     aSDomain        complement(12443..12718)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_HRD51_RS15950_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.30E-16"
                     /identifier="RREFam001.1"
                     /label="HRD51_RS15950"
                     /locus_tag="HRD51_RS15950"
                     /protein_end="258"
                     /protein_start="166"
                     /score="52.0"
                     /tool="antismash"
                     /translation="VSMNAMAHRVGDRLVLPSSDVHGNADRRSVRVRHTSPLSHIRRLA
                     PAAAPVPYAEVVAELTDRFPAVGHERISAFVAELVGLGLLVTDLRPP"
     gene            complement(13213..14466)
                     /locus_tag="HRD51_RS15955"
                     /old_locus_tag="HRD51_15695"
     CDS             complement(13213..14466)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="HRD51_RS15955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15695"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_205365077.1"
                     /sec_met_domain="LANC_like (E-value: 1.8e-37, bitscore:
                     127.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPSPLLPTGLAARANAVASVIRERLDSPAGADAHAARAAGQSEV
                     SFWNGASLSEGHAGLALLHLHAARTAERGAEGERSRDRAFSFVRAAFAATQEDALTHPG
                     LFDGTAGLAFALREVAADEPRFLPSLAALDEQLSRQVLAMELPRRPGAVAAHHYDLVYG
                     CAGVLAHLCHVRPATPLVEQALQRCLRYLLWVGADQRWAVEGRLDTGMSHGAAGIAAAL
                     ATAWRHGHRLPGQRLVLDRLVAWLLEVGSRGGRQLQWPRSVPVAPHPDDGDEAVPAWCH
                     GTGGVAAGLLAVADATGDRALEARAFAALDGLLDRIAAGDVPRSPTMCHGLAGCVALAH
                     EFAARGSEGAARGLARLVAELLDAAEPERALVYRDRETTGHVVDNPGLLTGAAGVSLTL
                     RAVATGRRPSWWRVLFLR"
     gene            complement(14556..14738)
                     /locus_tag="HRD51_RS15960"
                     /old_locus_tag="HRD51_15700"
     CDS             complement(14556..14738)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS15960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_15700"
                     /product="hypothetical protein"
                     /protein_id="WP_073442311.1"
                     /transl_table=11
                     /translation="MDEFDLDARVIVSADPAQTSLSPVASVASRVASKWAVKQTIRQTI
                     KMTAACAAVRTNGKC"
     misc_feature    complement(14824..14838)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.09"
                     /tool="antismash"
     misc_feature    14825..14838
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.47"
                     /tool="antismash"
     misc_feature    complement(14825..14840)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.5"
                     /tool="antismash"
     gene            complement(14931..15515)
                     /locus_tag="HRD51_RS15965"
                     /old_locus_tag="HRD51_15705"
     CDS             complement(14931..15515)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237369.1"
                     /locus_tag="HRD51_RS15965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15705"
                     /product="hypothetical protein"
                     /protein_id="WP_235093367.1"
                     /transl_table=11
                     /translation="MWQPDEILMTQKIAPLVNRYVFTLPESGEVIAFAEQKRFALQEQL
                     TLWTDEGRSREIGGFKAREVIDLGATYDVTGPGGDLVGSFRKDFKASFLRSTWHLTQGE
                     EGAAVGKERRVGVALARRMWDVVDLVVPLVTLPPVPFVYHFDFVRDGRPVLAVERKWGI
                     RDRYVIRIQDPGLDRTLALCMAVGLDALQGR"
     gene            complement(15705..17087)
                     /locus_tag="HRD51_RS15970"
                     /old_locus_tag="HRD51_15710"
     CDS             complement(15705..17087)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088364.1"
                     /locus_tag="HRD51_RS15970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15710"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_235093368.1"
                     /transl_table=11
                     /translation="MTRTTTPHHTDKALETRGAYGARERREPTPTPAARARTVLISGAS
                     TAGPALAHWLARYGYRPTVVESAPALRGGGFAVDFRGAAHLAVLQKMGVLEEIRRRRTG
                     GSSMTFIDARGNHVAALPPEFAGGDVEILRSELSRILYDHSCPTPTPHDDTTAPAAVAG
                     TTTAYLFGDSLTSLTETADGVHATFEHAPPRTFDLVIGADGLHSTVRRLAFGPEEDFVS
                     HLGYYVAGWDLPHGAAPDLAAHAVGYNEPGRLVTVGRVPRRADDPSYGGEAFCVFASER
                     LGHDRRDPQAQRAALVQAYEGAGWRTTELVGTVRDADDLYFDAISRVDAPTWSRGRIAL
                     LGDAAYGATVGGMGTGSAIVGAYVLAGELALAAGDHRRAFARYEQKLRPYVSRCQEGGR
                     GTGAFLAPLTQEAIAARNSALNDPAALTAMLQEGQDISADISLDDYPSLVHHDTGSDRN
                     GS"
     gene            17185..17934
                     /locus_tag="HRD51_RS15975"
                     /old_locus_tag="HRD51_15715"
     CDS             17185..17934
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088365.1"
                     /locus_tag="HRD51_RS15975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15715"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_205365083.1"
                     /transl_table=11
                     /translation="MAGDEKSSAFGDQAGSVELLWGGRERPSRGPKPALSLERITRTAI
                     GLADTGGLGAVSMQRVAAELDFTKMSLYRYVPGKAELVALMIDTAMGEPPEPAGAAAGD
                     WRGALRDWAQRLAAVFAQHPWLLSALVGPRVMGPNELGWTERALAALAGTGLTGGEQLD
                     AVLVVSGHVRAIAQVSASMGVGGAPAKEPEAALSAALNELLVGRSERFPALSAALAGAA
                     GGETREQAWEFGLERILDGLEAYAGRG"
     gene            complement(18008..19183)
                     /locus_tag="HRD51_RS15980"
                     /old_locus_tag="HRD51_15720"
     CDS             complement(18008..19183)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0000902 - cell morphogenesis [Evidence
                     IEA]"
                     /GO_process="GO:0008360 - regulation of cell shape
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541960.1"
                     /locus_tag="HRD51_RS15980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15720"
                     /product="rod shape-determining protein"
                     /protein_id="WP_235093369.1"
                     /transl_table=11
                     /translation="MASSTSSGTYDIGIDLGTANTLVYARGKGVVLNEPSVVAVNAAGD
                     VVAVGSEAKRTIGRTPSGITAMRPLREGVIADFDAAEQMLRALMKKALPSRRFSRPRVV
                     ICVPSGITGVERRAVIDSARGAGAREVHLIEEPMAAAIGAGLPVAEPVGCMVVDIGGGT
                     TEVAVVSMGGLVTAQSVRVAGDAMDAAISTYIKKEHGLAIGERTAEDIKIAIGSAVWTP
                     DDDRPLPTRLTVGAASDSVSEPASDAETDAESLADRAARPSPHSYTVRGRDHLSGLPRL
                     QEITAEEIRAALAEPVEAIVRAVHNTLDDCPPELSGDIIERGIALTGGGALLRGLDRRL
                     REEMGVPVVVADAPLDCVVNGTAKCVDEFATLHGLLTGAKEQPRKNVRLGM"
     misc_feature    complement(19236..19256)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.04"
                     /tool="antismash"
     misc_feature    19256..19271
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.25"
                     /tool="antismash"
     gene            complement(19271..21412)
                     /locus_tag="HRD51_RS15985"
                     /old_locus_tag="HRD51_15725"
     CDS             complement(19271..21412)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018531959.1"
                     /locus_tag="HRD51_RS15985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15725"
                     /product="FUSC family protein"
                     /protein_id="WP_235093370.1"
                     /transl_table=11
                     /translation="MTWSRALKEATRSGLTIERAKLTPMIAIRGTVGVAIVLGLCLWRG
                     NPALAVSSAFGAFSAGIVTFQRSMRPRPVLALAVAGALAISTFLGYLAAAHVVWFVLLL
                     TGWTFLAGMAWAIGPVSGLVGTQTVAIMLITVTLPTSVLGALEHAALIACGGLVQAALI
                     VLFPVRPWGIQRDTLADALAAEADYARRLRHDPVAPFDPAPLMDARAAATVTPRQARRR
                     PVQLHGPRGLAERVRPVLASLADPVVGAPLEGPERDRARELLGAAATVLDAVAYAVRHA
                     SPVRLPPEAVAALEVPASGPMLRGPARRTAYRLISLLADAVELTDEPVEATRPTTEAER
                     GHLLRPSVPRLVPVALRALRREARWSSHVLRHALRVAAVAAAGYLLGAALHFGHGYWAP
                     LASVMVMRPDFAQTYSRGVARFAGTVVGVTLAGALMALAHPGAYVSAALALLCVFLMYL
                     LMRTGFSVTSACIAAYVVFLLGIVGAGWEQTVQERLVLTLVGGVLAMLSYALFPAWETP
                     RLRDRLADWLTTNGRYALAVVDGYARPAERRPRQVREALLDARAARAAWEATEARAEKE
                     PVRHRGLPLGGAHAASTALATMGRVTMILEAHPPDRDARPSPGAAAFAAALRPALDSAA
                     RAVRDGEAMDWGEPHAAWERWSAEGEHEGVAVRATELLLDALDDLAEALPPTPDDPPPT
                     ASAPGRIRPRRNHSAPPVV"
     gene            21853..22875
                     /locus_tag="HRD51_RS15990"
                     /old_locus_tag="HRD51_15730"
     CDS             21853..22875
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571347.1"
                     /locus_tag="HRD51_RS15990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15730"
                     /product="alpha/beta hydrolase-fold protein"
                     /protein_id="WP_205365089.1"
                     /transl_table=11
                     /translation="MRKSLFKPVIALIALTVLGTTAGCGTSDDSQGAPVRFSGPRSGAA
                     MQTAPAGKNSLVQMPTHPINFQETSKVGGAGGNTPIAVTTYHGKKSGFTGKVWVWAPPE
                     YYEKKNANKGFPVMEALPGAYGYPVNYWIGSDLKLEESLATWSKEGKSLPFIVVMPVLN
                     PNDKQYYDGSDIPGQPKIGTWLSKDVPDLVRENFRTLKTRNAWCIMGSSSGGFSALKNV
                     LQNPNDFKVAIPNGPDIVPDSPLWRGHLKEMRENNPEVLARQLNAHGGPDVYLAFQDGS
                     KEYTVLPKVRKFLAQYGHGHVKTRLQIVPNGTHSGQTYVTGLGMGTMQWVSAHMQGPTG
                     "
     gene            complement(22955..23383)
                     /locus_tag="HRD51_RS15995"
                     /old_locus_tag="HRD51_15735"
     CDS             complement(22955..23383)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571346.1"
                     /locus_tag="HRD51_RS15995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15735"
                     /product="hypothetical protein"
                     /protein_id="WP_235093371.1"
                     /transl_table=11
                     /translation="MSRTASRPVAACAAALGLTLAATAPAAATVRSDPAGRHTAAEIHR
                     FLAGFYGQHGPTPHQRAHQVSAYLKDRAAHTDGYDLLLCAQNTPQAITVGPVTTAQSAG
                     VGWATVTTGWDGGATRSFTAYVRLESHPITLQDVDCGQ"
     misc_feature    complement(23377..23387)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            complement(23532..24392)
                     /locus_tag="HRD51_RS16000"
                     /old_locus_tag="HRD51_15740"
     CDS             complement(23532..24392)
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088370.1"
                     /locus_tag="HRD51_RS16000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_15740"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_067351380.1"
                     /transl_table=11
                     /translation="MTATTPAAAPGYRARRTLPLRVEARRQLRRRRTLVIGAILTLLPF
                     VLVAAFAIGGDPSTRNTGRISLMTTATASGANFAATALFVSAGFLLVVPVALFCGDTVA
                     SEASWASLRYLLAAPVPRARLLLSKLTVGLVFSAAAMLLLPLVALAVGTAAYGWGPLQL
                     PTGGALAPGDAVLRLALVTGYVFVSQLVTAALAFWLSTVTDAPLGAVGGAVGLTIVGNV
                     LDQVTALGDWRAVLPAHWQYSWADALQPQLEWSGMLQGASVSVSYALVLVALAFRGFAR
                     KDVVS"
ORIGIN
        1 gcttcgccac cgacggaccc gcgctgacca agaagctggt cggcatcgtc accaccgacg
       61 acccgcgcgt caccgcgggc ggcacgctga cgctgttcga caccacgacc gcgcagaagc
      121 tgttcctcgc ccccggccgg ttcgacgcga tagcggtggc ggccaagccc ggcgccgacg
      181 agcgcgcgct gaccgcccag gtgcagtccc tgcttctcgc caagggcgcc cgggccacca
      241 gcggcgccga cctggccgcc gaacagtccc ggcagatcgc cgagaacacc acgcggctga
      301 cgaaggcgct gctgggcttc gcgggcatcg cgctgttcgt cggggtgttc atcatcgtca
      361 acaccttcac catgctgatc gcccagcgca gccgtgagat cgccctgctg cgggccgtgg
      421 gtgcctcgcg ccgccaggtc gtccgctccg tcctcatcga ggccgccctc gtcggactcg
      481 gcgcctccgc cgccggattc gcgctcggcc tcggcatcgc caccgccctg caccccctgc
      541 tcagcaccgg cggcgccgag ttgcccgacg gccccctggt cgtctcgccc accgctccgc
      601 tggcatcgct ggcggtcggc gtcgccgtga ccgtcctggc cgcctggcta ccgtcccgca
      661 gggccgcgaa gatcgcgccg gtcgcggtgc tcagcagcgc cggcctggcc ccgcccgccc
      721 gctccctgaa ggtccgcacc gtcctcggca cactcctgac cggactcggt gtcgcggtca
      781 tgctgtacgt ctccacgctg aggaccagca aggagacgaa cctgatgacc gccatgctcg
      841 gcggcgccct caccctctgc ggcatgatcg tcctggcccc gctgctctcc cgcccgctga
      901 tcaccctggc cggcaaggtc accgcgcgct tcggcgtcag cggcaagctg gccaaggaga
      961 acgccctgcg caacccgcgg cgcaccgccg cgacctcctc ggccctgatg atcggcctca
     1021 ccctgatcac cggcctcgcc gtcggcgggt actccacgca gcgggccctc gacgaggaag
     1081 cgacccaggg cctggccgcc gactacaagg tctccaacag cgcctaccgc ggcctcgaaa
     1141 ccgccgcggc cgacgacatc gccgaactgc cgggcgtcgc ggcggccgcc cccgtcgcct
     1201 ccgcaaactt cgacgcccag ggcgtcttcg ccacgatcac gggcacggac ccgaagacgt
     1261 tcggcagggc agcggacctc acattccagg ccggctcgct gcgtgacgtc ggcccaggga
     1321 ggatcgcggt ctccgaccag ttcgcacggc aggccggact gcatgtcggc gacacgatcg
     1381 acgccgacat gcacaccggc gggggcacgc cgaacacgaa gaacaacaag aacaacaaga
     1441 agaagctgac ggttgtcgcc gtctacgcca agacccgcgc cgcgtacgac gcgctgggcg
     1501 ccgtggccga cgtcctcccc tccgccgaaa cccacaagct cgacaacgtc ctggtcaagg
     1561 ccgagcccgg caaggccgca ggactggagc agaagatccg ccaggcgctc ggcaacagcc
     1621 cgctgctgaa ggtccagacc cgggaacagc tcatcaaggc cggcagcgga tccatgacga
     1681 ccgtcctcaa catgctgtac gggctgctcg ccatggccgt cgtcatcgcg gtgctcggcg
     1741 tcgtcaacac cctcgccatg tcggtcttcg agcgcacccg ggagatcggg atgctgcggg
     1801 ccatcggcct ggaccgctcc gggatcaggc agatggtccg gctcgaatcg gtggtcatct
     1861 ccctcttcgg cgccctgctc gggatcggca cgggcacctt cctggcctgg gccgcgggca
     1921 gtctgacaac ggcgtcgatg ccgctgtacg agacggtcct gccctgggcc aagctcgggc
     1981 tcttcctcgc gctggccctg ctgatcggag tgctcgcggc catctggccg gcccgcagag
     2041 ccgcacggct gaacatgctc cgggcgatcc aggcgcacta ggacccgcga acgccatggc
     2101 ttacccgcac atgcccgcac atgcccgcgc cgcagagacg acaccgaccg agaaaacatg
     2161 aactcgacgt acctgctgcc gatccgtacg gccgcactgc tcttccccgc actggccctg
     2221 ctgatgttcg tgccgacggc gatcgtcctc taccggcggc acggcgtgct gacccgctgg
     2281 cgagcactgt cgctgtacgg cggcgtgtac tacgcactca ccgccttctg catgacgatc
     2341 gtgcccctgc ccaaaccctc ggtggacgtc tgcacggcgt atccggcctt cgcccacccc
     2401 cagctcacac cgggcgtcgc cctcaccgac atctggaagg aggcacacca ccacgccacc
     2461 ctcgacgcac tggtactgca caaccccgcc ttctggtcga acacgttcaa cgtgctcctg
     2521 ctgctgccgc tcggggtctt cgtacggatc cacttccgac gcggcctcac cgccgccacg
     2581 gcagccgggt tcaccacctc actcttcttc gaactgaccc agtacaccgg gctctggggc
     2641 ctctacgcct gcccctaccg cctcttcgac gtcgacgacc tcatcgccaa cacagcgggc
     2701 gccgccctcg gctgggccgt cgccggaccg ctcgcccgcg cactgcccga gctggacacc
     2761 ctcgacgacc gggctctcgc ctccggcaag gtccccttcg gccgccgcct cgtcgcactc
     2821 atcctggaca cgacgggcgt caccctactg agctggctga tcggggccct cacgtaccgc
     2881 gaactcggcg agggcacact gctgtgcgcg ccgccgtcgg ccttcgcact ctggttcgtc
     2941 gtcatcccat ggctgacggg cgcgacaccg ggcaaacacg tactgctgct gcgactggtc
     3001 acgccggacg gcggacggcc gagccccgcc aggctcgcac tgcgcgccct ggtgctgagt
     3061 cctcccctcg tgctcgcatg cctcgccgcg ggcgcggtcc tcgccatcgc cgcagacccc
     3121 tccctgctga tcaagatcgc cgacgaggtc gtccatcgaa ccctctcggc agacccggcg
     3181 tcagcgttcg tcctgctgct gcccccagcc gcctgcctga ccctgatcgc cgcatacgtg
     3241 aaatccgtcc gccgccaccc gcagggcctg ggcccgcacg aaacccgctc cggcatccgc
     3301 aaccacgccc tcccccacac ccgagcccgt accccggcca caccagccac accgcccaac
     3361 ccagccgatc cacacgtgcg gagcctgccc cggcggcagc tccgcacgga ccggaatccc
     3421 gggtcggccg agtcaggtcg ggtcgccgcg ccgtcccccc ggccccgacc gtccttcttc
     3481 cgcgcagccc gctgggtagg tgcctgcggt cttcgcggct gcgtgcgacg gttcggttgc
     3541 ggatcggggc gggtaaggcc ggaatctgag ggattttcgc aatcttctag aatgcggggt
     3601 ggaagattct cgggggttcc cgggaccgtc ccggctcttc agtcggccgc gggcatgggc
     3661 atgggcgggg catcgcaacc gagaatccgt ggatccggat gtctttggcc cgtgaaaacg
     3721 gggagcacca atgagcacta ccgggcgcag gtcgttcttg cgtggcagag ccttcttccg
     3781 gggcaggtcc tggttcgggg gcaggtcctg gttccggggc ggagactggt tccggggcgg
     3841 agccttcttt cgttttcgtg gtgagggggt gcggggggat gggggttccc gccgggccgc
     3901 gctcgttgtc gacggggtgg tcatcgcggc ggccgccgcg gagctgctga ctctctacga
     3961 tgcgctcgac gccctctcgg cgctcgtgtg cccgccgtcg ctgttcgcgc tggtgctgcg
     4021 ccgccgcttc ccggtggccg tgttgttcgc caccttgcct tccatggcca ccggccatct
     4081 gtggctggct cccatgatcg ccatgttcac ggtggcgtcc aggaccgccc gccgtgccgt
     4141 cgtcggcgtc gcgacggccg cgctgttcgc ggcgaccatg tggtccgggt acgacctcga
     4201 cggcggggcg gtggactgga gccaccatct gttcgtggtc gaggtggctc tcatgttcag
     4261 cgtcggcccc gccgggctcg ggctgctctt tcgcacccgc tccgagctgc gggccaggct
     4321 cgcggacctg atcgcctccc aggcgcacgg ccgccgcctg gaagccgagc gggccgtggc
     4381 ggaggagcgc acccgtatgg cccgcgagat gcacgacagc gtttcgtacc acctgggcat
     4441 catcgccgcg cagtccggcg ccctgtgggc gaccgccccc gacgacaccg tccggcggga
     4501 tgccgagtcc atacgccgtc acagcgccga cgccatggcg gagctgcggg agatcgtcgg
     4561 ggttctgcgg cacgggccga gccgggcgga cgggacggac gcccggctcc gcaacgtgcc
     4621 gaccctggtg gcggaagccc gcctggacgc gacgctcgac tgtggcgctc tggagaccca
     4681 caccctcgcc ccctccgtgg aacgagccgc ctaccgaacg gtccaggagg cgctcaccaa
     4741 cgtccgcaag cacgctcccg gtgccccggt cgccgcctcc gtacgccctt cggcccgggg
     4801 cgacacgctc gtcgtcgagg tccgtaacca gccggcaccc cggacacctc cgccggtcgc
     4861 ccccgtgctc gacgtgcccg cgagcggcta cggcctcgcg gggttgaggg aacgcgtcac
     4921 tctcgtcggc ggcgcgttcc gggcggaggc cactgcggac ggcgggttcg tggtacgtgc
     4981 cgagttgccg ctcgggactg ccgctcccgt cgcgtcgggg ccggcgtcgg gccatcagcc
     5041 cgcgaccgcc gcccagggcg agtcggggtc ccgctcgtag accgacacgt gccgcaggct
     5101 ggcggaggtg tacggggtgc cgcaccagtc ctccgtgcgc tcgacgagcc gcagcccgga
     5161 cagctcggcc agcagatcga tctcgaaggg gaaggcgtag cgcagtacgt gctcacgggt
     5221 ggccggggct ccgccgtcga tgatggtgtg cgtcgagagc atgagctgtt gcgagcggtc
     5281 cacggcgagc gtgtccagca tgacggtctg ctcgtcgagg tggcgcatcg agaagtccgg
     5341 cttctccagg tggtggtacg gcgccgggtc gaacgcctcc aggacgaacc ggccctcggg
     5401 cgcgagctgt tcgcggacca gtcgcaaagt gccgagctgc tgttccttcg tgatcgcgac
     5461 gaagaaggtg ttcagcagca gggtcacggt gtcgaagaca ccgccggtgc cttcctcggt
     5521 gaagtcaccg aactgggtgg tcaccgcggt ctgcgggttc tgcctgtgca gttcgtccag
     5581 catggcctcg gagccgtcga tgccgtgcac ccggaagccg cgcccggcga gcgggacggc
     5641 gatccggccg gtgccgacgc ccagttccag gatgcgcccg tcgggcggtg tacggccggc
     5701 gacgaactcg accgcctggg cggtgtcgtg gtcgatcgga tacatgcggt cgtagacgct
     5761 cgccagcttc tggtcgtaga gcgcgttgcc gagggccatg gtggttcaac tccaaacggc
     5821 ggggtggacg ggcggggggg ggaagagttc ggaggccggc ccgccgccgt tcgggcgttc
     5881 agcgggtctc ggccagggcc gacggacgca ggtggccttc cgcggcggcg cggtgtgccg
     5941 ccacggcggc ctggacgcga ttggccagcc ccagtttcgt caggatcgag ctgacgtgct
     6001 cctttgccgt cgacgcgctc agcagcagcc ggcgcccgat gtccgcgttg gtcaggccct
     6061 cccccagcag ttcgagcacc tgctgctccc gctcggtgag cgtgtccagg cgcgggtccc
     6121 gctcgccgtg gcgcggaccg gcgccgaggt agccgtcgac gacgatgcgt gctgcggccg
     6181 gggagagcac ggttccgccc gaggccaaca cccggaccgc gtcggcgagt tcctgcggtg
     6241 tcgcgtcctt cagcaggaag cctgccgcac ctgagcgcag cgcggccgcg atgtcctcgt
     6301 cccgcaggaa cgtcgtgagg acggcgaccg cgggcgggtc ctggtgggcc cggatccatt
     6361 cgagggcggt gagtccgtcg acctccggca tgcgcaggtc gagcaggacc acgtcgggcc
     6421 ggtgggctgc cacggcctcg cggacctccc gcccatcgca ggcgaccggc acttcgatgt
     6481 ccgcttcgct ctccagaatg cgctgcatgc acgaccgcag cagaatttca tcgtcgacga
     6541 tcatcacccg gatcatccac gccccccgtc agagcagccc taatcggtca aacctcgttc
     6601 aaggtaccaa cagacaaggg attcgagagc gcgggggccg gaaagggagc gcgatggaca
     6661 tcgttttcga cgtgatatcg cggagcggat cagacgggct cggagaggtg ctccgtgatg
     6721 agctccacca gcttcgcgtc ccacgtggag acgagcagtt cgatcttctt cgcggagccg
     6781 tcctcggccg tcacggtgca gtccagggcc gttccgaagc gcccgccgcc ggtcgccgcg
     6841 gcggccggac cggaaagcgc cagcgctctt gggccgggcc cgtccaggac gaccccggac
     6901 gcgctcacca cgattctccc gcgatgcatg gcggggcctt gtgcccgaat tcggaaccgg
     6961 cagcgcagcg tgatcctttc accgcgccga aaggcggcaa tgcgacgcgc tgaacgtgcc
     7021 ctgtcaagac tcttgccgcc tatccagaac accgtgtcca tcagggaaaa caggacgaat
     7081 tccagaagca tgtgattgcc cctcaactca acttgggatg gctctcgttc aaaacccggg
     7141 gccctcatcg gcccgggggc acggcccggt cctgcatcgc ccccacgatg gcccgcacgt
     7201 cggccagcgc ggcgtcgagc ccttcggtca gcaggacccc cgcacagctc agcgcgatct
     7261 ccgtggcccc cgcctcaccg taaccggtga gccggtccgc cagctcgtca ggggtgccgt
     7321 aggcgaagac cccgccctcg accagtgcgc cggccccggc ccacgggtcg gccgcgtcca
     7381 cgccgaggcc cgccgagcgg agcatcgccg cgtagtgctc accgcccagg tgcagctcgt
     7441 gcgccgcgaa cgcgagccgg cgcgggtccc ggccgggtct gcgcaccgcg cacggcacga
     7501 tcgacgtcac cccgggggcc gccctgtccc gggaggcggc gccgcgcgcg agcgcaggca
     7561 cgatccggtc cctgaggtag gtggccggcg tcagcagggt gatcgccacg tcggcgacct
     7621 ggcccgccgt gtacgccatg cgcggccgca gcacgccgac accgagcgag acgggagggt
     7681 gggggacctg ggggagcccc tcgtccacgc gcacatagcg cccctggaag tccaccaact
     7741 cgccgtccag gagccgtcgc acgacggtca ggtactcggc gacggcggtg cgcggactgt
     7801 cgtacggtgc gccgcgcagc gccgtcacga acgccgggtc gcccgtgctg tagccggcga
     7861 cgacgtcggc gccggtcagc agggccagcg acctggcctg tatcgccgcg tccagcgggt
     7921 ggcgcagagc cgtcagggcc acgctggtgc cgaccggcac gcggatgccg cgcccggcga
     7981 ggtgcgcgaa ggcatggtgg gtgtcgacca gcaccgactg ccccatgtag agccgctcca
     8041 gggacagctc ccggacgact tcgccgaagg cggtgaggtg gtccaggtcg tacgccatga
     8101 gcgggtacat gagggacagc gggggtgttc gggtcatggg tgcttcctgt gcggcggcgg
     8161 tcatgcggag gctcccggca ggtaggcgtc ggcctggagc cggaagaggt gggcgtacgt
     8221 cccgccgtgt gcgagcagtt cctcgtgggt gccctcttcg atgagcgaac cgccctccac
     8281 gaccaggatc ttgtcggcga tgcggacggt ggagaaccgg tgggagatca ccagggacgt
     8341 cgcccgggag cagatcgtgc gcagccggcc gaagatgtcg gcctcggcct cggcgtcgat
     8401 cgcggcggtc ggctcgtcga ggatcgcgat cggcgcgtcc cgcaggaagg cccgcgccag
     8461 ggcgatcttc tgccactggc cgccggacag ctggtggccg ccctcgaagt gccttcccag
     8521 tgtggtgtcg taggtgtccg tgaggcggtc gatgaactcg gcggcgccgc tggacccggc
     8581 cgccgcgcgg aggcgggcgt cgtcgtcgag gtgttcgagg cggccgaagc cgatgttgtg
     8641 ccggacgggc atctcgtagc ggatgaagtc ctggaagacg acgccgatgt tccgctggag
     8701 gtcgtcggtg tcgtactcct ccaggggcac gccgtcgacg aggatgcggc cgctggtcgg
     8761 ctcgtagagg cgggagagca gtttgacgat ggtgctcttg cccgcgccgt tcgcgccgac
     8821 gatcgcgcag caggtgtcgg cggggatgaa gcaactgaac cggtcgaggg cggtggtcgt
     8881 ggtgccgggg tagcggaagg tgacgtcctg gaactcgatg ccgtgcgtca ggcgccgggg
     8941 gaagggccgg gtgccgcccg tgatgcgccc gtcgggcagc gtcagatagt cgaagaggtt
     9001 ccccgtgaac agcgtgttct ggtacagggt ggccacgccg agaagcagcc cggtggccgc
     9061 cgcgtgcacc gcacccagcg cctgcaggta cccggcgagc tcgccgatcc ggccgttgtc
     9121 cgcggtggat ctgagggcga agaccagcgc gcccgccgag cagcccacgc tgaccaggcc
     9181 gagcgccgcc gaccagccgt gccggcggcg tgccagcgcc cggtcgacgc ggaagaactc
     9241 ctgcacgagc gaccggtagc ggcccacgag gtgggggccg agctggtaca gcttcacttc
     9301 cttgtaggag gcgtccgtcg tcgtcaggtc ctggtagtag aaggcacggc gccggtcctg
     9361 cgcacggtgg tactcgatcg cgtagccctg cttgctgaac accacgtgcg cggcgagcgc
     9421 gggcaacggc gccagcagga tggccagggc gatccagacg ttccaggaga acagcaccca
     9481 gctgaccatc accagtgatg ccagcgcggt gagcgtgcgc atcatctcct cgaacacctc
     9541 gaaggcggtg ccgctgccgc tctcccgcag cgcgcgctgc agccggtcgt acgcctcggg
     9601 gtcctcgtag gcgctgaggt ccatgcgggt gcccttgacc atgacccgct caccgatctt
     9661 ggccgtgaac tccaactgga gcagggagtt caggtactgc gagaacgacg tcaggacgtg
     9721 ctccgccacc gcgaccgcga cgagaccggc cgcggcccag gtgagccggt ccatggcgtc
     9781 cggcacccgc gcgagggcgt cgacgacggc ctgcacggcc ccggcggtca gccagattcc
     9841 ggtggccggc acggcggcgg tgagtaccgt ggccacggcg agcgcggaga ccctcagggg
     9901 gctgagtccc cagaacgtac gcaggacgag ccaccagtag cgcaggtccc gggagaggcg
     9961 ccggtgctcc tcgggcacgg cctggtccct ggcttcctga tcagtcacgg ggcctccccc
    10021 gcaggcagtt caggacgtgc ccccagacca ggtagcagcg gtcctcggcg gggcggtcca
    10081 tgggcagcag ccggttcacc tgcatgtgcg cgaggctggc caggacggcg tcccgggtgc
    10141 cccacagcgt tccggccgcc tccgcgtccg cgacggcccg cgaggcccgg cggacggcgt
    10201 cggcctggcc ggcgagaacc ggggcgaggc gctcgtggtg ggcgcggccc cgcaggtgcg
    10261 ggcggcggtc ccagggggcg agcagctcgc acagatagtc gcggtccttc ttgtactgct
    10321 cgcgggctcc cttgtcctcg gcgggccggg gcatggcggc gagacgctcg cggacgtcga
    10381 gaccccactg ggcgtacagc gcgtcgacgg ccgccagggt gaccgcttcg gcggtgagtc
    10441 cgggctcctt gtcccagagg agaccgagca gttggacgga gacggcgctg ttcgccgcga
    10501 agaactcctc gatgtggtcg tacacggcgg gaccgccgta ccggctcacc tcggggtggt
    10561 acgtggcgac ctccagacgc tcggcgatcc cccgccggac gagggagcgc ccccagtcca
    10621 ggagcggttc cagggcggac gtgccgccgg ccggtgtacg ggtcctgatg cgcagatgcg
    10681 catcggggtc ggcgtaccgg atgtagaacc accggtcgac gtcggcgccc gcgtcccgta
    10741 tctcctgggc gagtccggcc agttcgaccg cggcgatctc gtcgtgcagg tcacgggcgg
    10801 cgtacagctt gaggtacgac cactcggagc cgggcagatg gctggggtgg gcggcgggac
    10861 gggccttgcg tcgtatcccc tccgccgcgg ccgcgcgggc cgacgccgta tccggtggcg
    10921 gcgcggcctc ggtgccggcg ggcgccgcca ggagcggaat gacgacctcg gcgaggtgcc
    10981 cgcgtccggc gctgtcgcgc agccaggtcc tgtcgggatc cggcagcgcc tcctggagcg
    11041 tgacccgctc gtcggccgcc cgcagatcgg tcaacagctc gtccgcgcag gccgggtggt
    11101 cgaggtccag gagcagccgg ttgtcgtcgt cggccaggta gacgtggcgg ggaacgcccc
    11161 aggtgcggcg ccactccgtc aactccgcgg cggtgcgcgg tacggggacg ggagcggtgt
    11221 ccagcggggc ctgcgcgccg gccggataga ggttccactc ggcggcccgt acgacgaccc
    11281 ggccccgcac gacgcgcggc aggtaagggg cgccctcgac cgggccccag gtgaagccgg
    11341 tggggatcgc atacctggcg cgcgaaacct ccagcaggaa ccggcacacg ttgggcgcgc
    11401 cgagcgggct gagcatgtgg ttctggacga ccaccagttc gcgcccgagc cgtgccgagt
    11461 agagccgcag gccgtcgtcg gtcgcgccga catggatgtc ggagaggtcg atgatccggt
    11521 ccggggcggc ggagggcgcg acgttgacgg ggatctcgta gccgtggacg gcgggccgga
    11581 tcgccacgtt ggcgccgcgc ccgttgccgg gcaggtacgc cagctcggcg accacgacgt
    11641 cgggctccag ggcttcccgg gcacgggcgt aggagcggag gcgttcggcg gcggagggcc
    11701 cgaggaggtg gaagaaccgt ccgaaggtgc gtccgccctc gccgagaccg tcgctgttga
    11761 gcacggcgcg ccagtcgccg tcgtcgatcg cacgggcact ggatgcggcg atctggacgt
    11821 acgcgtcgac gccggggcac ccgcgccggg tatcgccctc gtccgcgggg acgagcctgc
    11881 gcagcgcctc gtcgctcagc tcaacctcgt cggctccgct ccgccacgcc tgggaggcca
    11941 gggcgaccag ggcccgcgcg gtccgcgggt ctccttcgcc gccggtctgg tgcatgacca
    12001 tggcgcgggg tggattgagg tagctgttgg gggcgtcgag gccgcgctcg gcgctgagga
    12061 gttcgaggac ggggacgagc gcgtcgcttc cgtaccgctc catgaacgcc tcgtgatacg
    12121 gcacgaggtg gtcgtatccg ccgggcgccg cccgacccag ccgggccagg cagccgacgg
    12181 cctcggcgac ctcgtcggcg acctggcggt tgagggccgt atcgacgagg ccgagggcgg
    12241 agtcgacctg gaagggctgg tgccggtatg cggggacgag ggtgcgttgg gtcaggcgca
    12301 gcctgtcgag cgcgccggtg tcgtcgtgga cggcggtccg ggtcaggtcg acgacctcgc
    12361 gcagtccggc cacggcgggg tgctccaccc cggcggcggt gagccgggcc aggacgtacg
    12421 cctccgggca gggatcggtg acgggcggcc gcaggtcggt gacgagcagc ccgaggccga
    12481 ccagttcggc gacgaacgcg gagatccgct cgtgcccgac ggccgggaac cggtcggtca
    12541 gttcggcgac cacctcggcg tacgggacgg gcgcggcggc cggggcgagg cgccggatgt
    12601 ggctgagcgg gctggtgtgc cgtacccgca ccgatcgccg atcggcgttg ccgtgcacat
    12661 ccgaggaagg caggacgagc cggtcaccca cccggtgcgc catggcgttc atggacacgc
    12721 tgagccgccc gagcacctcc ggcgcgccct ccaggtcctt caccagagcg agcagccatc
    12781 ccatgtcggc ccgcacccgg gcggacacga ggggggtctc gccgagccgg gcggtggtgg
    12841 tctcgccgaa ggagccgagt gcgacgccgg agaaggcccc gaagggggtg gggcgggtgc
    12901 tcatgcgggt gaggtagcgc agggcccggg agtggacgcg ccgcatctcc ttgccgctcg
    12961 cacgtccctg tgcggcctcg accttggcca gcccgtcgag cagtccgctg ccggcggcga
    13021 cgagcccgtg gcgtacgcgg gggtcgtcgg ccatggcgcg caaccgggcg cgggtgcggg
    13081 cggggtcgcg gtcggcgagc gtctcccgcc agacctcgac cggcagggca ggcgcccgca
    13141 ggagagggaa gtcgagggct tcgtaccgcg gcatggggcg ggtcaggtcc ttgtcgattg
    13201 cgtcgattgc gttcatcgga gaaagagcac ccgccaccaa ctgggcctcc ggccggtggc
    13261 tacggcacgg agggtgaggg agacaccggc cgcgccggtg aggagcccgg gattgtcgac
    13321 gacgtgcccg gtggtctcgc ggtcgcggta caccagggcc cgctcgggct cggcggcatc
    13381 gagcagctcc gccacgagcc gggcgagtcc acgcgcggcg ccctcgctgc cccgcgcggc
    13441 gaactcgtgg gcgagcgcga cgcatccggc gaggccgtgg cacatggtgg gcgagcgcgg
    13501 cacgtccccg gcggcgatcc ggtcgagcag cccgtccagc gcggcgaacg cccgggcttc
    13561 cagggcccgg tcgccggtcg cgtcggcgac ggcgagcagc ccggcggcca ctcccccggt
    13621 cccgtggcac caggcgggca cggcttcgtc cccgtcgtcg gggtgcgggg ccacggggac
    13681 ggaccgcggc cactggagct gccggcctcc gcggctgccg acctccagca gccacgccac
    13741 cagccggtcg aggacgaggc gttgcccggg cagccggtga ccgtgccgcc aggcggtggc
    13801 cagggcggcg gcgatacccg ctgcgccgtg ggacatcccg gtgtcgagcc gtccctcgac
    13861 ggcccaccgc tgatcggcac cgacccacaa caggtaccgc aggcaccgct gaagcgcctg
    13921 ctcgacgagc ggggtcgcgg ggcggacgtg gcacaggtgg gcgaggacgc ccgcgcaccc
    13981 gtagacgagg tcgtagtggt gagcggcgac ggcaccgggc cggcggggca gctccatggc
    14041 caggacctgc cgggacagct gttcgtccag cgcggcgagg ctgggcagaa aacggggctc
    14101 gtcggccgcg acctcgcgca gcgcgaaggc gaggccggcc gtgccgtcga agagccccgg
    14161 gtgcgtgagg gcatcctctt gtgtggcggc gaaggcggcg cgcacgaagg agaaggcccg
    14221 gtcgcgcgac cgctcccctt ccgcgccgcg ctccgcggta cgcgctgcgt ggaggtggag
    14281 gagcgccagc ccggcatgcc cctcgctgag ggaagcgccg ttccagaagg acacctcgct
    14341 ctgcccggcg gcgcgggcgg cgtgcgcatc ggcgccggcg gggctgtcga gtcgttcccg
    14401 gatcacgctc gcgacggcgt tcgcgcgggc ggcaagtccg gtcggcagaa gggggctggg
    14461 gtgcatgtgt ggggctctac aggctcttcg gagggggtcc tccgtttcct tccggaggac
    14521 cccaccgcgg tgatcggact cgatcggcag cgcggtcagc acttgccgtt cgtgcggacg
    14581 gcggcgcagg cggccgtcat cttgatcgtc tgccggatgg tctgcttgac ggcccacttg
    14641 ctggcgacgc gcgaggcgac gctggcaacc ggggacagcg acgtctgagc cgggtcggcg
    14701 gaaacgatca cgcgagcgtc aaggtcgaac tcgtccatga atgtacaaca cctttcattc
    14761 cgtaaaacca accgcccacc gaggaaacga ggaagggatt ccaaaggagt ttccgaggcg
    14821 gtcagagaat gaatgtaatg aggccgagga cgctcttgaa cccgccgacc ttcctattct
    14881 tcccccacca tgtggcggga cggtccgccc ggctgtccgg tgcccgaccg tcagcgcccc
    14941 tgcagggcgt ccagcccaac tgccatgcag agcgcgagcg tccggtccaa ccctggatcc
    15001 tggatacgga tgacgtaccg gtcccggatc ccccacttcc gctcgaccgc caggacgggc
    15061 cgcccgtccc ggacgaagtc gaagtggtag acgaacggca cgggcggcaa agtgacgagc
    15121 ggcacgacga gatcgacgac gtcccacatg cgtcgcgcaa gcgccacacc gacccgccgc
    15181 tccttgccca cggcggcacc ctcctccccc tgcgtcagat gccaagtgga ccgcagaaaa
    15241 gacgccttga agtccttgcg aaagctgccg acgagatccc caccgggccc tgtcacgtcg
    15301 tacgtggccc cgaggtcgat cacctcccgc gccttgaatc cgccgatttc ccgggaacgg
    15361 ccctcatcgg tccacaaggt cagctgctcc tgcaacgcga accgcttctg ctccgcgaag
    15421 gcgatgacct caccactttc cggaagcgtg aacacgtacc ggttcacgag cggggcgatc
    15481 ttctgcgtca tgagaatttc gtcgggctgc cacatgcagg aaccgtaagc atcgacagaa
    15541 cgcacactcg tgcatctcaa ggcggagcag accccctccg accggagggt ggaaaagggc
    15601 cgagtggtca cctccctctc ctgaattccc gtgtgaatcc cccagccact gaccgccccg
    15661 ccgactcccg tgggcatcgc cgagcccgag ggagccggtg gcgctcaact gccgttccgg
    15721 tccgacccgg tgtcgtggtg gacgagcgag ggatagtcgt cgagggagat gtcggcggag
    15781 atgtcctggc cctcctggag catggccgtg agggcggccg ggtcgttgag cgcggagttg
    15841 cgggccgcta tcgcctcctg ggtgaggggc gccaaaaacg cgcccgttcc gcggccgcct
    15901 tcctgacagc gcgagacata cggccgcagc ttctgctcgt accgggcgaa ggctcggcgg
    15961 tggtcgccgg ccgcgagggc cagttcgccg gcgaggacat aggcgccgac gatcgccgag
    16021 cccgtgccca tcccgccgac ggtggcgcca taggcggcgt cgccgaggag cgctatccgc
    16081 cccctcgacc acgtcggtgc gtcgacgcgg cttatggcgt cgaaatagag gtcgtcggca
    16141 tcccggacgg tcccgacgag ttccgtggtg cgccagcccg cgccctcgta cgcctggacg
    16201 agggccgcgc gctgggcctg tgggtcgcgg cggtcgtggc ccagtcgctc ggaggcgaag
    16261 acgcagaatg cctcgccccc gtaggagggg tcgtcggcgc ggcggggcac gcggccgacc
    16321 gtcaccagtc ggccgggctc gttgtaaccg acggcgtggg cggcaaggtc cggcgccgcg
    16381 ccgtgcggga gatcccagcc ggcgacgtag tagccgaggt ggctgacgaa gtcctcttcg
    16441 gggccgaagg cgagccggcg caccgtggag tgcaggccgt cagccccgat gaccaggtcg
    16501 aaggtgcggg gtggggcgtg ctcgaaggtg gcatggacgc cgtcggcggt ttcggtgaga
    16561 gaggtgaggg agtcgccgaa gaggtatgcg gtggtggtgc cggcgacggc ggcaggggcg
    16621 gtggtgtcgt cgtgaggggt gggagtgggg cagctgtggt cgtagaggat gcgggagagt
    16681 tccgagcgga ggatctccac gtcgccgccg gcgaactcgg gcgggagcgc cgccacatga
    16741 ttcccccggg cgtcgatgaa ggtcatggaa ctaccgccgg tgcggcgccg cctgatctcc
    16801 tccaggacgc ccatcttctg cagtaccgcc aggtgcgccg caccgcggaa gtcgaccgcg
    16861 aagccgccgc cacggagggc cggcgccgac tcgaccacgg tggggcggta gccatagcgg
    16921 gcgagccaat gggcgagggc cgggccggcg gtgctggcgc cggagatgag gaccgtccgg
    16981 gcccgtgcgg cgggggtcgg cgtcggttcg cgcctctcgc gcgccccgta cgccccccgc
    17041 gtctcaagtg ccttgtccgt gtggtgcggt gtcgttgtgc gcgtcatcgg acgcccccct
    17101 gtgtctgcgt gctgtggcga cacaacaact gtatccgccg gacacggatc tatatacccc
    17161 cggacacagt tttaggatgc ggaggtggct ggagacgaga agagcagtgc gttcggggat
    17221 caggcgggca gcgtcgagct gctgtggggc gggcgcgaac ggccgagccg gggccccaag
    17281 ccggcgctga gcctggagcg gatcacgcgg acggccatcg gcctcgccga caccggcggg
    17341 ctcggcgcgg tctccatgca acgggtcgcg gcggagctgg acttcacgaa gatgtccctg
    17401 taccggtacg tgcccggcaa ggcggagctg gtcgccctga tgatcgacac ggcgatgggt
    17461 gaaccgccgg agccggcggg cgccgcggcc ggcgactggc ggggcgcgct gcgggactgg
    17521 gcacagcggc tcgcggcggt cttcgcccag cacccatggc tgctgagcgc tctcgtcgga
    17581 ccgcgggtca tgggccccaa cgaactcggc tggacggagc gcgcgctggc ggcgctcgcg
    17641 ggcaccgggc tgaccggcgg cgagcagctg gatgccgtgc tggtggtgag cgggcacgtc
    17701 cgggccatcg cgcaggtgtc ggcgtcgatg ggggtgggcg gcgcccccgc gaaggagccg
    17761 gaggcggcac tgagcgccgc gctgaacgag ctgctcgtcg ggcggtccga gcggttcccc
    17821 gcgctgagcg ccgcgctggc gggcgccgcc gggggcgaaa cccgggagca ggcttgggag
    17881 ttcgggctgg agcggatcct ggacgggctg gaggcgtacg caggacgggg gtgagaagcc
    17941 cgctctccct gcgtacgccc cgcggggccc tcgtcgtcgt gctgcgcgcg gggccctcgc
    18001 cgtcgcgcta catccccagt cgcacgttct tccgcggctg ttccttggcg ccggtcagga
    18061 ggccgtggag ggtggcgaat tcgtcgacgc acttggcggt gccgttgacc acgcagtcca
    18121 ggggggcgtc ggcgaccacg accgggacgc ccatctcctc gcggaggcgg cggtccagcc
    18181 cccggagcag ggcgccgccg ccggtgaggg cgatgccgcg ctcgatgatg tcgccggaga
    18241 gctccggcgg gcagtcgtcc agggtgttgt ggacggcgcg gacgatggcc tcgacgggtt
    18301 cggcgagggc ggcgcggatc tcttcggcgg tgatctcctg gaggcgcggg aggccgctga
    18361 ggtggtccct cccgcggacg gtgtaggagt ggggggaggg gcgcgccgcc ctgtccgcga
    18421 gcgactcggc gtcggtctcg gcgtcggacg cgggctcgga tacggagtcg gacgcggcgc
    18481 ccacggtcag gcgggtgggg agcgggcggt cgtcgtccgg ggtccagacc gccgagccga
    18541 tggcgatctt gatgtcctcg gcggtgcgct cgccgatggc caggccgtgc tccttcttga
    18601 tgtacgtgga gatggcggcg tccatcgcgt cgccggcgac ccgcacggac tgggcggtga
    18661 ccaggccgcc catggagacc acggcgacct cggtggtgcc gccgccgatg tcgacgacca
    18721 tgcagccgac cggttcggcc accgggaggc ccgcgccgat cgcggcggcc atcggctcct
    18781 cgatcaggtg cacctcgcgg gcgccggcgc cccgtgcgga gtcgatgacg gcgcgccgtt
    18841 cgaccccggt gatgccggag gggacgcaga tgacgacccg ggggcgggag aagcggcggc
    18901 tgggcagggc cttcttcatc agggcgcgca gcatctgctc ggccgcgtcg aagtcggcga
    18961 tgacgccctc ccggaggggg cgcatcgcgg tgatcccgga gggcgtgcgg ccgatggtgc
    19021 gcttggcctc cgacccgacg gcgacgacgt cgccggcggc gttgacggcg accacggagg
    19081 gctcgttcag caccacgcct ttgccgcgcg cgtagacgag ggtgttggcg gtgccgaggt
    19141 cgatgcctat gtcgtacgta ccggacgaag tgctggacgc catggggagt tcgcttgctc
    19201 tctctcggga ggacattgcg ccgcagagag cgccattgac gtgccaatga cgctaattgc
    19261 gggcaattat ctagactact gggggtgcgg aatggttcct gcgggggcgg atgcgcccgg
    19321 gtgcagaagc ggtcgggggc gggtcgtcag gggtcggggg cagcgcctcg gcgaggtcgt
    19381 cgagggcgtc caggagcagc tcggtggcgc ggacggcgac gccctcgtgc tcgccctcgg
    19441 cgctccaccg ctcccaggcg gcgtgcggct cgccccagtc catcgcctcg ccgtcgcgga
    19501 cggcccgggc ggcgctgtcc agggcggggc ggagggcggc ggcgaacgcg gcggcgccgg
    19561 gcgagggccg ggcgtcccgg tcgggcgggt gcgcctccag gatcatcgtg acccggccca
    19621 tggtggcgag cgcggtgctg gcggcgtgcg ccccgccgag cgggaggccg cggtgccgga
    19681 ccggctcctt ctcggcgcgg gcctcggtcg cctcccacgc ggcgcgggcc gcgcgggcgt
    19741 ccagcagggc ctcgcggacc tgccggggcc ggcgctcggc gggccgggcg tagccgtcga
    19801 cgacggcgag cgcgtaacgg ccgttggtgg tcagccagtc ggcgaggcgg tcgcggagcc
    19861 ggggcgtctc ccaggcgggg aacagcgcgt aggacagcat cgcgaggacc ccgccgacga
    19921 gggtgagcac gaggcgttcc tggacggtct gttcccagcc ggcgccgacg atgccgagca
    19981 ggaagacgac ataggccgcg atgcaggccg aggtgacgga gaagccggtg cgcatcagca
    20041 ggtacatcag gaagacgcag agcagggcga gggcggcgct gacgtaggcg ccggggtggg
    20101 ccagtgccat cagggcgccg gccagggtca cgccgacgac ggtgccggcg aagcgggcga
    20161 cgccgcggga gtaggtctgg gcgaagtcgg ggcgcatcac catgacggag gcgagcgggg
    20221 cccagtagcc gtggccgaag tggagggcgg cgccgagcag gtagccggcg gcggcgaccg
    20281 cggcgacgcg gagcgcgtgc cgcaggacgt gcgaggacca gcgggcctcg cggcgcaggg
    20341 cgcgcagggc gaccgggacg agccggggga cgctggggcg cagcaggtgg ccgcgttcgg
    20401 cttcggtggt ggggcgggtg gcctcgacgg gctcgtcggt gagttcgacg gcgtcggcga
    20461 ggagggagat caggcggtag gcggtgcgcc gggcgggccc gcggagcatc gggccgctgg
    20521 ccggtacttc gagggcggcc accgcctccg gtggcagccg gaccgggctg gcgtgccgta
    20581 cggcgtacgc gacggcgtcc aggacggtgg cggcggcgcc caggagttca cgggcgcggt
    20641 cgcgttcggg cccctccagg ggggcgccga cgaccgggtc tgccagtgag gcgaggaccg
    20701 ggcggacacg ctcggcgagg ccgcgcgggc cgtgcagttg tacggggcgg cggcgggcct
    20761 ggcggggtgt cacggtggcg gcggcccggg cgtccatcag gggcgcgggg tcgaacgggg
    20821 cgaccgggtc gtgccgcagc cggcgggcgt agtcggcctc ggcggccagg gcgtcggcga
    20881 gggtgtcgcg ctggatgccc caggggcgca ccgggaagag gacgatgagg gcggcctgga
    20941 cgaggccgcc gcaggcgatc agcgcggcgt gttcgagggc gcccaggacg gacgtcggga
    21001 gggtgacggt gatcagcatg atcgccacgg tctgggtgcc gacgaggccg gagaccggcc
    21061 cgatcgccca ggccatgccc gccaggaacg tccagccggt gagcagcagg acgaaccaga
    21121 cgacgtgggc ggcggccagg tagccgagga aggtggagat cgccagcgcg ccggcgacgg
    21181 ccagcgccag caccgggcgg ggccgcatgc tgcgctggaa ggtgacgatg ccggcggaga
    21241 aggcaccgaa ggcggaggag accgcgaggg cggggttgcc gcgccacagg cacaggccga
    21301 ggacgatggc cacgccgacc gtgccgcgga tcgcgatcat cggggtgagc ttggcccgtt
    21361 cgatggtcag cccggagcgg gtggcttcct tcagcgcacg cgaccaggtc atagcgagag
    21421 aatacgggcc gggagcaggg gcggccgggt gccgggctgg gggtgccccc ggcggcggct
    21481 gggggacggt gcggaagggc gacccggatg ccttcgcggc gggttcccga ggggccgctg
    21541 cggaccctcg caggggcgtg cggcggggtg ccggaggcgg cggccggcgc cggggcgcgg
    21601 acgcacgccc ggtgtgccgg aagggggcgc gtgggggggc catcgggcgc ccgcgttgcg
    21661 cctccaccgg gaaaatcacg gtaaaccaga tctccgttgc gcgtaaacac cacaggtcag
    21721 agccggtcgg ccagtttcgt tcccgagggt gcgagcaagc agacacccca ggagggaaac
    21781 ctgtcccggc cccgccccct cttgttggcc ggtcgggaca actcccggcc cgttcgccaa
    21841 ggagaaggtc ccgtgcgcaa atcccttttc aaaccggtga tcgccttgat cgccctgacc
    21901 gtactcggca ccacggccgg ctgtgggacg agcgacgact cccagggcgc gcccgtacgg
    21961 ttcagcggtc cgcggtcggg tgccgccatg cagaccgcgc cggccggcaa gaactcgctg
    22021 gtgcagatgc ccacccatcc gatcaacttc caggagacca gcaaggtcgg cggggccggt
    22081 gggaacaccc cgatagccgt gaccacctac cacgggaaga agtccggctt cacggggaag
    22141 gtgtgggtct gggcgccgcc ggagtactac gagaagaaga acgcgaacaa gggcttcccg
    22201 gtcatggagg cgctgcccgg cgcctacggc tacccggtca actactggat cggctccgac
    22261 ctcaagctgg aggagagcct cgccacctgg tcgaaggagg gcaagagcct gcccttcatc
    22321 gtggtgatgc cggtgctcaa ccccaacgac aagcagtact acgacggcag cgacatcccc
    22381 ggtcagccga agatcgggac gtggctgagc aaggacgtcc ccgacctcgt ccgggagaac
    22441 ttccgcaccc tgaagacccg caacgcctgg tgcatcatgg gctcctcgtc gggcggcttc
    22501 tcggcgctga agaacgtgct gcagaacccg aacgacttca aggtggcgat ccccaacggg
    22561 ccggacatcg tcccggactc gccgctgtgg cggggccacc tcaaggagat gcgtgagaac
    22621 aaccccgagg tgctggcacg ccagctgaac gcccacggcg gacccgacgt ctatctggcc
    22681 ttccaggacg gctccaagga gtacaccgtg ctgccgaagg tgcggaagtt cctcgcgcag
    22741 tacgggcacg ggcacgtgaa gacgcggctg cagatcgtgc cgaacggcac gcacagcggc
    22801 cagacctacg tcacgggtct gggcatgggc acgatgcagt gggtcagcgc ccacatgcag
    22861 gggccgaccg gctgaggacg ggccgaccgg cgggcggtcg cggcggacgc ttcggtccgc
    22921 ggcgaccgcc ctcgtcgtat ggcgggcggg cggttcactg cccgcagtcg acgtcctgga
    22981 gcgtgatcgg gtgcgactcc aggcggacgt aggcggtgaa gctgcgggtg gcgccgccgt
    23041 cccagccggt ggtgacggtg gcccaaccga cgcccgcgga ctgggcggtg gtgaccgggc
    23101 cgacggtgat cgcctgcggg gtgttctggg cgcagagcag caggtcgtag ccgtcggtgt
    23161 gggcggcacg gtccttgagg taggcggaga cctggtgcgc gcgctggtgc ggggtggggc
    23221 cgtgctggcc gtagaagccg gccaggaagc ggtggatctc ggcggcggtg tggcggccgg
    23281 cggggtcgct gcggacggtg gcggcggcgg gtgcggtggc ggcgagggtc aggccgaggg
    23341 ccgcggcaca ggcggcgacg ggacgcgatg cggtacggga catggcaggt cctcaccttc
    23401 agggcgtgtg actgcgtaga cagccatgtc cggcgcatgg ttgcggtgcc ggacaacccg
    23461 aacaaagggg gacgggtgtc cgcatccggc cgcgccgccc ggcggccctg cggcccctgt
    23521 ccccgccccg gtcaggacac cacgtccttg cgggcgaagc cgcggaaggc cagtgcgacg
    23581 agcaccagcg cgtaggacac cgacaccgag gcgccttgga gcatcccgga ccattccagc
    23641 tggggttgga gggcgtccgc ccaggagtac tgccagtgcg cgggcagcac cgcacgccag
    23701 tcgccgagcg cggtgacctg gtcgaggacg ttgccgacga tggtcagtcc gacggcgccg
    23761 ccgaccgcgc ccagcggcgc gtcggtcacc gtggacagcc agaacgccag cgccgcggtg
    23821 accagttggc tgacgaagac atagccggtc accagcgcca gccgcagcac cgcgtcgccc
    23881 ggggcgagcg cgcccccggt gggcagttgc agcgggcccc agccgtacgc ggcggtgccc
    23941 accgccagcg cgaccagcgg cagcagcagc atcgcggcgg cgctgaacac cagccccacg
    24001 gtcagcttgc tcagcagcag ccgggcccgc ggcaccggcg cggccaacag atagcgcagc
    24061 gacgcccagc tcgcctccga ggccacggtg tccccgcaga acagcgcgac cggcaccacc
    24121 agcaggaagc cggcggagac gaacagcgcg gtggcggcga agttggcgcc ggaagcggtg
    24181 gcggtggtca tcagactgat ccggccggtg ttccgggtgc tgggatcgcc gccgatcgcg
    24241 aacgccgcga ccaggacgaa cggcagcagc gtcaggatcg cgccgatcac cagggtgcgg
    24301 cggcggcgca gctggcggcg ggcctcgacg cgcagcggca gggtgcggcg ggcgcggtag
    24361 ccgggcgccg ccgccggggt ggtcgcggtc atcgtccgtc tcctccgatc agggtgagga
    24421 aggcgtcctc caggcggcgg tgcgggccga cgcggtgcac cgggac
//
