LOCUS       NZ_CP054019            51064 bp    DNA     linear   CON 28-JAN-2024
DEFINITION  Streptomyces sp. A1-5 chromosome.
ACCESSION   NZ_CP054019
VERSION     NZ_CP054019.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. A1-5
  ORGANISM  Streptomyces sp. A1-5
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9459690)
  AUTHORS   Dashti,Y., Sumang,F.A.M., de los Santos,E.L.C., Alcantara,E.P. and
            Challis,G.L.
  TITLE     Structural revision and biosynthesis of polyketides FXJ15321 and
            FXJ15322 from Streptomyces sp. A1-5
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9459690)
  AUTHORS   de los Santos,E.L.C.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-MAY-2020) Warwick Integrative Synthetic Biology
            Centre, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL,
            United Kingdom
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUN-2019
            Assembly Method                   :: Flye v. 2.4.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology :: Oxford Nanopore MiniION; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/28/2024 04:28:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,328
            CDSs (total)                      :: 8,230
            Genes (coding)                    :: 7,847
            CDSs (with protein)               :: 7,847
            Genes (RNA)                       :: 98
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 383
            CDSs (without protein)            :: 383
            Pseudo Genes (ambiguous residues) :: 0 of 383
            Pseudo Genes (frameshifted)       :: 156 of 383
            Pseudo Genes (incomplete)         :: 280 of 383
            Pseudo Genes (internal stop)      :: 26 of 383
            Pseudo Genes (multiple problems)  :: 73 of 383
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:08:01
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1287742
            Orig. end                         :: 1338806
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP054019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Philippine National
            Collection of Microorganisms.
FEATURES             Location/Qualifiers
     region          1..51064
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene"
                     /product="hglE-KS"
                     /region_number="9"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="(hglE or hglD)"
                     /tool="antismash"
     cand_cluster    1..51064
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="(hglE or hglD)"
                     /kind="neighbouring"
                     /product="terpene"
                     /product="hglE-KS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21158
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21158
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11158](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11158)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(725..1336)
                     /locus_tag="HRD51_RS05760"
                     /old_locus_tag="HRD51_05625"
     CDS             complement(725..1336)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012301.4"
                     /locus_tag="HRD51_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05625"
                     /product="response regulator transcription factor"
                     /protein_id="WP_235092451.1"
                     /transl_table=11
                     /translation="MRVVLAEDHPTVRAGTRAFLEPEGFIVVGEAACEREALEIVSEQQ
                     PDVLMLDMKLESGLALKAIPQFLAAAPEMGILVQSCYEDRAIICGALAAGAAGYLLKSS
                     PVSELVLAVRTVASGERYVQPSLGAGLARTQGREPELQLRERQVLGLLAEGHTNREVAA
                     RLTVSVRTVESVRAALRARLGLVTRADLVAYARQNRSADV"
     misc_feature    2890..2907
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     misc_feature    3517..3534
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     misc_feature    complement(3573..3582)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(<3819..4319)
                     /locus_tag="HRD51_RS05775"
                     /pseudo=""
     CDS             complement(<3819..4319)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055863.1"
                     /locus_tag="HRD51_RS05775"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MEAAASTSADEKFIEELVACAQADGLQLTGEGGLLQQLTKRLLES
                     ALDGEITDHLGYDKHDPAGKNGGNSRNGKRSKTVLTDVGPVEIEVPRDREGSFEPQIVK
                     KRQRCLTGVDEMVLSLSAKGLTHGEIAARLAEVYGAEVSKQTISHITDAVMEGMSDWQN
                     RPLD"
     misc_feature    4332..4352
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.27"
                     /tool="antismash"
     misc_feature    complement(4333..4353)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.46"
                     /tool="antismash"
     misc_feature    4462..4476
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            complement(4473..7661)
                     /locus_tag="HRD51_RS05780"
                     /old_locus_tag="HRD51_05635"
     CDS             complement(4473..7661)
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541948.1"
                     /locus_tag="HRD51_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05635"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_235092452.1"
                     /transl_table=11
                     /translation="MPVWRRGARWRGATWAVIGALLVSLAVSSGPGIAQAATPTQPRTQ
                     QDDGHETADRYLEIVGNLRNTMTRNGNGQAQPVADTPGVGRVMQQPNWQIIGIGALGGL
                     DQNAVQLVIDPSDLYVRGIYVRARNVLYAYTHDGHTTGEVYIPQDVQNSLARNLRRVPL
                     SFSERYREVFGIELGATPLRNAVRYIADFNGRTLDDLRESFEHVIMPIAEGARFGIFAG
                     RIAQAMRGGQQTFHLDATRAGDTWVEYLIHNWADLSNDIRQAAQNDPRAEGTEFTQRRT
                     FENTNHGHTFRYFLSYLDIARRIATLKPPPRRNGRVGIAAVPRDGEPRIGPPPGASNDN
                     EKCRPDGMPRTPGVNTPYCLAYTSEGREWMGKTHDRRVIGYFAGWRTGKDGSPAYRPQN
                     VPWGQITHLNYAFAHVTDNKLAIGDQDVENIRLLNEQKAEHPRVKTLISVGGWSQTRGL
                     YTLVTGSDAQSKIDTFADSAVEFIRQNHFNGVDIDFEYPTSLENTGNPEDWPVSNPVRG
                     ELMAGYGKLMKTLREKLDRASAADGTYYLLSSAVSSSGYLVRGMENHDPAKYQDYVDVM
                     AYDFHGTWNGYVGPNAPLYDDGKDTELADAGVYSTKEYGGIGYFNTDWAFKHFRGALQA
                     GRINIGIPYYTRGWSDVSGGNQGMWGTSKMPDQSQCPAGTGSGPGAPPGTRPCGEGARG
                     IDNIWHDTTNAGGELPAGTNPMWHAKNLEANIEPNYGSQVGLDPERNASDRLTGNYARH
                     WDDTTKTSWLWNEQKKTFLSTTDTQAVDAVADYVTRSGAGGVMIWELAGDYSCPATPTA
                     ENPCGIGYTMTSRLDEKLGHAGDYGNSRAAGSTAQLPARTANLEVDLVDYPAGSAKLYP
                     LEPKVRLTNNTGKAIGGGAELSFDIPTSTSPLVKDGNWQGSDTPDGLWRLTPGHTGPNA
                     GTGLKGDFHRVTTKIEYCQVIPAGKSIDIPIKYYLPITGPANATLTTSGGTYGLASDNR
                     RGAEDAGEVTDTGCNAPDWDAAKAYDPATQSHEDVTVKYNGHYWRAKWWTQNNAPGTGP
                     DADHEPWKDLGPAS"
     misc_feature    complement(6072..6074)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     cand_cluster    6424..51064
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(hglE or hglD)"
                     /kind="single"
                     /product="hglE-KS"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    6424..51064
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[26423:31064](-)"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(26424..31064)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(hglE or hglD)"
                     /neighbourhood="20000"
                     /product="hglE-KS"
                     /protocluster_number="2"
     gene            complement(7699..8322)
                     /locus_tag="HRD51_RS05785"
                     /old_locus_tag="HRD51_05640"
     CDS             complement(7699..8322)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS05785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_05640"
                     /product="hypothetical protein"
                     /protein_id="WP_235092453.1"
                     /transl_table=11
                     /translation="MRLTRLRSRATAVMAGLAAALATVALTAAADAASGTHPAAVSVTP
                     VADTAPGPAGKDRQADARRLTSQRSPRLADADDGTVNTDYSIVNTTVTTSRVWYKTVPA
                     PPFRLTDMGVAVIWQIPSDRAAYDKHKNDWIGIYEGNGTKGTRVYWDWTCPSSDYKEQC
                     GEAFGATVIATGKLTHGKEYTAAYYSDGGASSNGTLRATYTFWA"
     misc_feature    complement(8390..8402)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.13"
                     /tool="antismash"
     gene            8771..>9104
                     /locus_tag="HRD51_RS05790"
                     /old_locus_tag="HRD51_05645"
                     /pseudo=""
     CDS             8771..>9104
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542857.1"
                     /locus_tag="HRD51_RS05790"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="HRD51_05645"
                     /product="SDR family oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQEQRVDLVTGGGTGIGAATARLLRTAGHQVVISGRQPEPLRRGG
                     RGDRSAGPPFRRRRPRGRARARRDDGDDLLET"
     gene            9122..9265
                     /locus_tag="HRD51_RS05795"
                     /old_locus_tag="HRD51_05650"
     CDS             9122..9265
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_05650"
                     /product="hypothetical protein"
                     /protein_id="WP_235096240.1"
                     /transl_table=11
                     /translation="MAAQHELSQTRTAYQQLCARLPWSAEPHSGWNDTSPAVTPGRSVP
                     ST"
     gene            9300..9965
                     /locus_tag="HRD51_RS05800"
                     /old_locus_tag="HRD51_05660"
     CDS             9300..9965
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013676.4"
                     /locus_tag="HRD51_RS05800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05660"
                     /product="Tn3 family transposase"
                     /protein_id="WP_268826843.1"
                     /transl_table=11
                     /translation="MRRRVVAATNKVESFNRFSQWIGFGNRGATADNDPIEQEKAMKFN
                     ALVSSTAWLGHRSPESTQHYAKITPNTLAGAYNDAGYFERNVRTIEVLVDRDAVTSEAA
                     ASGEPWQYYDLGHGFCTYTFFEQCPHRIACARCDFYTPKTSSKGQLLEAKDNLQRMLAS
                     VPLSDDERAASMRPEAALDQLLERLVDVPTPTGATAREIGVPATATLLPIVAVNQGKG"
     gene            complement(10001..11158)
                     /locus_tag="HRD51_RS05805"
                     /old_locus_tag="HRD51_05665"
     CDS             complement(10001..11158)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="HRD51_RS05805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05665"
                     /product="terpene synthase family protein"
                     /protein_id="WP_235092454.1"
                     /sec_met_domain="T1TS (E-value: 3e-48, bitscore: 164.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSDVALRPEELTYRLPEMDLILPLRMHPMLPQAQYDTPAWVRSY
                     VGDVAGTDVEEWLNAGYELWTCLCYPHAREDRILRMSRLCTVLTIVDDETTRDTPFGNS
                     SAYAAAAVEQWEDLLRGTQPVPQEAPAWWRLAHDTWHDLTTDMPDGLRERFITYLMRIL
                     RGSVTEVAVREHATELDLDAYMELRRETVYGTYCWLLAEYALGLDFTDMFTEHPELFGV
                     WQDASDHLIVFNDLISLRKEWFVECDDRMSASWILRRQHGFTVQEFADWTAARLAEIER
                     SYVKRCQDILTTSWGNTPAMRAYLCEIGHTMAGSLFFSRSSARYHAPGLLWNGITEATM
                     TMHPHRSTIAPVHHNRPDHRAPYLYLSPLAQGHECARSSTGARSQ"
     gene            12076..12543
                     /locus_tag="HRD51_RS05810"
                     /old_locus_tag="HRD51_05670"
     CDS             12076..12543
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024980.4"
                     /locus_tag="HRD51_RS05810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05670"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_235092455.1"
                     /transl_table=11
                     /translation="MTRPQLAEARRVRAAELFGQGRASAEIARMLEVSAESVRRWKRVW
                     EEGGADALRRRPATGRPPKLDDAQVEQVRTALEQGAQAHGFEADLWTLERVGLVVERMT
                     GVSLSRASVWRLLTGRLGWSLQRPERRAVERDDSEIARWITHEWPRIKRGR"
     gene            12540..13115
                     /locus_tag="HRD51_RS05815"
                     /old_locus_tag="HRD51_05675"
     CDS             12540..13115
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237296.1"
                     /locus_tag="HRD51_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05675"
                     /product="IS630 family transposase"
                     /protein_id="WP_235092456.1"
                     /transl_table=11
                     /translation="MNKRAWIVFLDESGVSLLPQVRRTYAPRGHTPLLRHRLNWKRASM
                     AAALGYHAAEPDRGPRLCFHLKPGSYDTIALIEVLEQLKVFYRGEQVVLIWDGLSAHWS
                     RAMRAWAAEQDWLTLERLPAYAPELNPVELLWSSLKKRELANLAGDHLADVADATEQGI
                     HRINHNRQLPWSFLTHTGLTIHPPTPQN"
     misc_feature    12903..12905
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            13249..13698
                     /locus_tag="HRD51_RS05820"
                     /old_locus_tag="HRD51_05680"
     CDS             13249..13698
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070686.1"
                     /locus_tag="HRD51_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05680"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_235092457.1"
                     /transl_table=11
                     /translation="MGAQFFPAWLERSRAEYAKDLVAAGQTPEEAHRRADESMARSFPS
                     GMPSPGHVVFDVVDDAGETVGYLWIGPDTSDDAGAWWIWDIAIDADKRGRGFGRMAMVL
                     GEEYARAQGAHALGLSVFGFNTGARGLYESLGYETTSVKMLKQLG"
     gene            13844..>15045
                     /locus_tag="HRD51_RS05825"
                     /old_locus_tag="HRD51_05685"
                     /pseudo=""
     CDS             13844..>15045
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011689697.1"
                     /locus_tag="HRD51_RS05825"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="HRD51_05685"
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSETIVENEAMEEPVVESAAEAVSDEQLIAMLVDRARTDGLQLTG
                     EGGLLQQLTKRVLESALEGEITDHVGYGKHDAAGRNSGNSRNGTRAKTVLTDVGPVEVR
                     APRDTAGTFEPQIVKKRQRRLTGVDEMVLSLSAKG"
     gene            complement(<15043..15816)
                     /locus_tag="HRD51_RS05830"
                     /old_locus_tag="HRD51_05690"
                     /pseudo=""
     CDS             complement(<15043..15816)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010353223.1"
                     /locus_tag="HRD51_RS05830"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05690"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLDHDARRDAFDFASHFREDFYGCLTWRGDTLFELGDAMLCEDGP
                     VISPVDLRLLAEHRRGHGALYDALNQGRIDTAGLRRALAMLPQPKAADGRLVLVVDVSA
                     WLRPDAPTSPDRLFCHVYGRSGRSSDQFIPGWPYSFVAALETRRTSWCQLLDAVRLGPD
                     DDVAEVTAAQVRRVVTDLIGQGQWEEGDDDILVVFDAGYDAPRMAFLLDGLLVEVLGRM
                     RSDRVMRRPTPTLKEYALAYPQGGRPPKHCKEFRFA"
     misc_feature    complement(15861..15874)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            16072..16395
                     /locus_tag="HRD51_RS05835"
                     /old_locus_tag="HRD51_05695"
     CDS             16072..16395
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577332.1"
                     /locus_tag="HRD51_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05695"
                     /product="hypothetical protein"
                     /protein_id="WP_235092458.1"
                     /transl_table=11
                     /translation="MLSEIDRLERTRNYLYPGDVSKAVRLWEDFVHRPARELWRDYDGL
                     WHDDDSLYLHWYCCGNPLEARLLLDAAMRAMSPRGARELQKIIDKLDAFWTPPSPWPTT
                     VGG"
     misc_feature    16533..16544
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            16533..17402
                     /locus_tag="HRD51_RS05840"
                     /old_locus_tag="HRD51_05700"
                     /pseudo=""
     CDS             16533..17402
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019067337.1"
                     /locus_tag="HRD51_RS05840"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05700"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSERKPYPSDLSDEQWSLIEPVITAWKDRHRSVSGHQGAYDMREI
                     VNAILYQGRTGCQWAYLPHDLPQKSATYYYFAAWRDDGTDQVIHELLRCQVRERARRLE
                     DPTLVVLDTQSVHAAVGVPAATTGYDPAKRVPGRKRGVAVDVLGLVIAVAVLAANVHDN
                     TAGIALLDQVAEHTGDTVRKALVDQGFKNQVVEHGAGLGIDVEIVERDPGYRGFLPQPK
                     RWRVEQTYGILILHRRLVRDYEHRMWTFA"
     misc_feature    16563..16565
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16839..16841
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17339..18112)
                     /gene="istB"
                     /locus_tag="HRD51_RS05845"
                     /old_locus_tag="HRD51_05705"
     CDS             complement(17339..18112)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="istB"
                     /gene_functions="other (smcogs) SMCOG1151: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062452.1"
                     /locus_tag="HRD51_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05705"
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="WP_235092460.1"
                     /transl_table=11
                     /translation="MTVMDTALRESLKALRLSGMLETLDARLAQAHGGELGHLDFLQVL
                     CQDEITRRETVAFQRRLKRAKFEQQVTLEEFDFTASSKLPAAQIRDLGALRWLHAGESV
                     ILFGPVGVGKTHIAQALGHLAVRQGAHVRFAKTSRILADLAGGHADRTWQKRIRELVRP
                     DVLILDDFAMRQLTAAQADDLYELVSERQGRSLIITSNRAPSDWYPLFPNPVVAESLLD
                     RLINTSHQVIMNGPSYRPNKRPKNTADKPAKTTVK"
     gene            complement(<18198..19709)
                     /gene="istA"
                     /locus_tag="HRD51_RS05850"
                     /old_locus_tag="HRD51_05710"
                     /pseudo=""
     CDS             complement(<18198..19709)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="istA"
                     /gene_functions="other (smcogs) SMCOG1213: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_176223647.1"
                     /locus_tag="HRD51_RS05850"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05710"
                     /product="IS21 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVDITEIYVHWYAGRSKSELAASLGVDRKTVRKYLAPAEAAGITP
                     GGPPMSEADWSKLIKEWFPRLADKRLRQVTWPEIDQHRDYIKDLLGTVTVSTIHQRLRD
                     EHKLKVSISSFRRWVHATLPDEVARSQVTVLRDEIEPGQEAQIDYGFLGQWINARTGKR
                     HRVWAFVMVLPCSRHMFVRPVLHLDQHAWTEAHVAAFHYFGGVPRRLVPDNLKTGVDKP
                     DLYDPKINKAYAELASHYGALVDPARASKPKDKPRVERPMPYVRDSFWRGREFTSVEHM
                     QAEAVTWSKQVAGRRQCRPLSGAAPMAVFETVEADTLLPLPPTPFVLARWSTATVGPDI
                     HIKVGRTLYSVPWKLIGRRVDVRSTATVVQVFLDGQLVKTHAALEQGKRTDKSDYPPEK
                     IAFQMRTPVWCRSQASQVGDACREVVDQLLEVNALYRLRAAQGVLGLRKKYGDRRLEAA
                     CARAIAVGDPTYRTIKGILIAGTETDPEPETSGDAGAAAFLHGPKR"
     gene            <19903..20016
                     /locus_tag="HRD51_RS42065"
                     /pseudo=""
     CDS             <19903..20016
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058979.1"
                     /locus_tag="HRD51_RS42065"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="HRTASSASRVYWAMSHVMIRRLTGTNTSTWREEAVSA"
     gene            20013..20411
                     /locus_tag="HRD51_RS05855"
                     /old_locus_tag="HRD51_05715"
     CDS             20013..20411
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131781.1"
                     /locus_tag="HRD51_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05715"
                     /product="hypothetical protein"
                     /protein_id="WP_039631487.1"
                     /transl_table=11
                     /translation="MNVRPLLEALDLQEEAARALADDLRAQIDDLQTRLREAETHLEHL
                     AITRKTVTSLADQLPAPPPELPEHPDYPRILAAFNESTGPLRAKDVCQALGHELLPKNV
                     EGTRAKLKRLVKLGILTEADTGCFTRRQ"
     gene            complement(20635..21960)
                     /locus_tag="HRD51_RS05860"
                     /old_locus_tag="HRD51_05720"
     CDS             complement(20635..21960)
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018657.4"
                     /locus_tag="HRD51_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05720"
                     /product="WS/DGAT domain-containing protein"
                     /protein_id="WP_235092461.1"
                     /transl_table=11
                     /translation="MKVPWGKPAVRGDHLTAGWKSYQRRNPDASTAIGFVFLCEGEHPT
                     RAELLDLVSTLTGHVPTASRPGSAGILEHQVTLAEAPDETKLGEVLGECYSASLPDEGW
                     DVWMVGYAPQRFALAIRFDHLLIDGVGGIQLLSRLASIPGTGFTPAVPVGDRDRLPSRT
                     APMPKSPARIGRFTVLTSARTVRALVAPLLGVPRASVLTPGTRAGADGMRYVWAQADYR
                     RLVSCAHALGAQPNDVILAALTGALRDWYAGCGLRPDGQVTALVPISIRRTNERDTHGN
                     RIVSSRISLPIDEPDVLARLNEIAQRSRTAKRLATHALLPPLLQLLPGPILSWGLQRNL
                     RPNVNTLLATTVAGPPIPLRVLGRSVQQILPIVFLPAGHRVAVAISRYAGTSFVCFTTD
                     RTLKGADSLPEMWSAAFDELCALAGPAASESESATSAAGARD"
     gene            complement(21966..23186)
                     /locus_tag="HRD51_RS05865"
                     /old_locus_tag="HRD51_05725"
     CDS             complement(21966..23186)
                     /NRPS_PKS="Domain: NAD_binding_4 (35-195). E-value:
                     1.2e-33. Score: 108.2. Matches aSDomain:
                     nrpspksdomains_HRD51_RS05865_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013530.4"
                     /locus_tag="HRD51_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05725"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_235092462.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.5e-14, bitscore:
                     52.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.6e-31, bitscore:
                     108.2, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILVTGASGIVGSALLRELDEAIALTHHKPVGTPSVRGDVTRPWL
                     GLHPADYRDLAARVDAVVHCAASVNFSITPEHLHRVNVVGTGHVLRFAEDAGAHLVHGS
                     TAFISRAGDHTPFGAYAASKAAGETLVRESGLPSCIARISTVIGDSHSGEVPRLQAFHY
                     LLGVALSGQMPFLPCTPGTHVDLIPRDTAAAALAALARDHSARGDHWITAGPAALPMER
                     IIDIAYDASAARAQNDEELRDIDQAVFRTRLIDPAVADTVINAVLARSSTSAAPSVIQR
                     AANLMTAYNDVDAFPTSLGRIPTGPTAPHPRIERDRPAPHDQLPGRIAPRHLGTPVTRQ
                     LGHSASPIGVDVGVRQAGKRHPRTPSQTVPLSSPNRELPTRGAFRAYPTPCRLVDPEGT
                     SVCHSER"
     aSDomain        complement(22602..23081)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS05865_NAD_binding_4.1"
                     /evalue="1.20E-33"
                     /label="HRD51_RS05865_NAD_binding_4.1"
                     /locus_tag="HRD51_RS05865"
                     /protein_end="195"
                     /protein_start="35"
                     /score="108.2"
                     /tool="antismash"
                     /translation="VRGDVTRPWLGLHPADYRDLAARVDAVVHCAASVNFSITPEHLHR
                     VNVVGTGHVLRFAEDAGAHLVHGSTAFISRAGDHTPFGAYAASKAAGETLVRESGLPSC
                     IARISTVIGDSHSGEVPRLQAFHYLLGVALSGQMPFLPCTPGTHVDLIPRDTAAAA"
     gene            complement(23183..26341)
                     /locus_tag="HRD51_RS05870"
                     /old_locus_tag="HRD51_05730"
     CDS             complement(23183..26341)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019589.4"
                     /locus_tag="HRD51_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05730"
                     /product="polyketide synthase dehydratase domain-containing
                     protein"
                     /protein_id="WP_235092463.1"
                     /transl_table=11
                     /translation="MISEQLRLATDLHERFLAAQADLHVPRPEPAGSPARTAHTVVDLG
                     GWYLDRAGRMTAGALVHDLLELLPQRDGVLDCELAFHQGLPAPGERLLSSLTLSGRSFR
                     GRVDGLLSLRGTESEGLSHGLPPEHTGAGFGPGEVTAFAEGRPADCFTGNDWELTRAHV
                     RSPGLGSRRTLLLHEITAFAPSMGLVATGRTLPKEWRTPAALLEGCFQALSFQLAATCC
                     TVHRDGWRFEPQPDEPARVRFLANAPDGTSRYHITIRSMTDTTVHADAVCTIDNRVVMR
                     AEGLAVHLVPDTPLTHWRLLGPATVQRTGNPGPPRVLAGLRGHDDPAAATVGSVRYDHA
                     AMLASAWGPVNEIFPGASDDAFRLPGPPYLFITRLTEVSATIGAPRPGSHLVAEYDVPE
                     QVWFREQSGTLPAAALMEAVLQPCGLLAGYLAARTTDAQLRIRNLDGHLTTTREVPPDV
                     RSLKTAVEFVGLDRWDGTVVETFRIRCEADGVPALEGTAVFALTHAAQLTSQTGLPVTD
                     ADRTRLALPCDRPVTDLRSRPARFFGHSARLPGPMLLMLDRITGYWPEGGPAGLGRLRA
                     ECDVRADAWYFKAHFFNDPVQPGSLGIEAMCQLLCYYLVECGVGDGFRFESVVPASWTY
                     RGQVVPTDALVTIELDVLDVELGPQGGHAEAEAWLWVDGRRAYHVPRLRVRAVPGTPDS
                     PSTVDTVLDPRSDTWLADHCPTWTVPAVPLMSTADLLARAASDHAGRPVRVLHDLRVQR
                     WLPVTGPTRLRMTCAGDTARLAVWHEAGALSRFAPVADATVGFEPPPRPERFAPLPDLV
                     DVPDPYEGAELFHGPSFQYLTALRRGSAGSSGMLDAGRGSVPRGALHQGLLDAALHVIP
                     HNELQRWEPAIGPGRMSFPHQLTRLAVFAPLPDCGEIEVEARFAGVLPDDLVAVDVQLC
                     RDESVLVSFQIVNMLIPAGPLAEVSGPARRAYLRDGHPDSRLLLTGSDGVLRRSDVGRI
                     DVLTGTANAVYGLPDGTRATDWLPHIALKEHIARTTGVHPRTVEVTGLDNVSWDDDSAT
                     VRTP"
     gene            complement(26424..31064)
                     /locus_tag="HRD51_RS05875"
                     /old_locus_tag="HRD51_05735"
     CDS             complement(26424..31064)
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (6-461). E-value:
                     7.5e-122. Score: 399.2. Matches aSDomain:
                     nrpspksdomains_HRD51_RS05875_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (565-848). E-value: 6e-59. Score:
                     191.8. Matches aSDomain:
                     nrpspksdomains_HRD51_RS05875_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (1019-1091). E-value:
                     5.1e-09. Score: 28.3. Matches aSDomain:
                     nrpspksdomains_HRD51_RS05875_PP-binding.1"
                     /NRPS_PKS="Domain: PKS_KR (1317-1487). E-value: 1.6e-43.
                     Score: 140.7. Matches aSDomain:
                     nrpspksdomains_HRD51_RS05875_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hglE-KS: hglE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998510.1"
                     /locus_tag="HRD51_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05735"
                     /product="type I polyketide synthase"
                     /protein_id="WP_235092464.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.8e-67, bitscore:
                     226.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="hglE (E-value: 7.8e-183, bitscore: 606.6,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 8.2e-57, bitscore: 191.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.7e-06, bitscore:
                     26.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLDHRIAIVGVSAITPGAPDVDAFWRNVIEGRDLMTDVPADRWL
                     IEDFYDPDPEAPDKTYARRGAFLPEVEFDPMALGVPPRNLPATDTAQLLALVAAERLLT
                     GLAGTGLDQVDGERVGVFLGCASLQLLGEMAARAGRPLWRRALLDSGLSEADADAVCDR
                     IADYSTPWQEATFPGLLSNVVAGRIANRFDLHGANFTVDAACASSLAALSVAADDLLLG
                     RSDLVITGGVDTLNDPLTFQCFSKTPALSSSGDCRPFDEHADGTMLGEGIALFALKRLA
                     DAERDGDQVHAVIRGIGSSSDGSGTSVYAPLDTGQARALRRAYEAAGYGPETVGLVEAH
                     GTGTAAGDAAELAALRSVFDASGRADRQWCALGSVKSQIGHAKAAAGAAGLLKATLALR
                     HRVLPPTIKVTRPNPGLKLAESPFYLNTQARPWIHTADHPRRASVSSFGFGGSNFHVAL
                     EEYAGMAPRTRHSVRCEVRPCELVVLSAATPQELFSRDLSGGLTAIARRSQETFRSTEA
                     HRLAVVASSTEDLAQKLEQARGRVGTEPFSTPSGVHYGVGRAPGRIAFLFPGQGAQYVG
                     MGADLAMHLPQAHAVWNRHEVSRLVFPAPVFTDAERQAQRRALTDTGAAQPAIAAHSLA
                     LLAVLDAVGVRPDCVAGHSFGELVALHAVRAYDEDTLMRLAARRGELMRGASGVMIALD
                     TGVDEVSELLARHDLAEAWIANHNASHQVVVAATAEAGALVQRHATAAGMTARVLDTSA
                     AFHSPLVASATEPLRAFLSGATVRAPLLDVYGNATAAVHPVEPAEIRRAIADHVTSPVR
                     FADMVRAMHTDGVRIFLEVGPGGALTGLIKQSLAAVHAIALDRPGRNGVTGLLDALGHL
                     CALGVPLDLAGLWHGPARPEPARPAMPMLISGGNHGRRYPPNAEYSPAAPAPVLSNSAA
                     LGGDTLRAVAEAQQEIARAHAAYLSMAEKSIDALTALEGTADHIVKPTAAAGPLHRPAV
                     PPPAPVAASVPAVAMSPAPVEVRSLDDLEAVVLAAVAEKTGYPVEILEPHMELEVDLGL
                     DSITRTQVLAALRPMFPQLEAVDRAQLAPLLTLRTVGEIADRLRALLDAPAPLTTAVPV
                     QAIRRHVLTLQRTPAPGSPMRGLGTLLVTDDGTGIAKEAVRLLTERGIHAEVGTTADLA
                     RTAAAGLLFLGGLADITSIDDALAVQRDAFRAAQVIGPRLRAEGGVFVTVQDTGGGFGH
                     RDAQRPWLGGLAALARTVRWEWPLAAVKAIDCRRADRTAAEVAAAVVDELLAGGPDLDV
                     GLAADGTRWTLALAELPDHVPGPSATDALGEAPVIVVSGGTGAVTAAALRALDSRHRAR
                     FVLLGRGPSREVDGLDQARYLHADVRDEDAVRAALTDVRTQWGPITGVVHAAGVLADRR
                     VEDKTEEQFDAVFQTKVDGLRALLSATREDPLRLLCAFSSVVAATGNGGQCDYAMANET
                     LNHVLAAEQATRPGTVVRSLLWGPWEAGMVTPELAEVFRLGGVDMIPLQAGARSFAEEL
                     TMTADDPRVLITAGRALARLREVARG"
     aSDomain        complement(26604..27113)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS05875_PKS_KR.1"
                     /evalue="1.60E-43"
                     /label="HRD51_RS05875_PKS_KR.1"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="1487"
                     /protein_start="1317"
                     /score="140.7"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="VIVVSGGTGAVTAAALRALDSRHRARFVLLGRGPSREVDGLDQAR
                     YLHADVRDEDAVRAALTDVRTQWGPITGVVHAAGVLADRRVEDKTEEQFDAVFQTKVDG
                     LRALLSATREDPLRLLCAFSSVVAATGNGGQCDYAMANETLNHVLAAEQATRPGTVVRS
                     LLWGPWE"
     CDS_motif       complement(26676..26759)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS05875_0008"
                     /evalue="6.30E-09"
                     /label="PKSI-KR_m4"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="1463"
                     /protein_start="1435"
                     /score="28.4"
                     /tool="antismash"
                     /translation="LLCAFSSVVAATGNGGQCDYAMANETLN"
     CDS_motif       complement(27018..27110)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS05875_0007"
                     /evalue="6.20E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="1349"
                     /protein_start="1318"
                     /score="6.1"
                     /tool="antismash"
                     /translation="IVVSGGTGAVTAAALRALDSRHRARFVLLGR"
     aSDomain        complement(27792..28007)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS05875_PP-binding.1"
                     /evalue="5.10E-09"
                     /label="HRD51_RS05875_PP-binding.1"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="1091"
                     /protein_start="1019"
                     /score="28.3"
                     /tool="antismash"
                     /translation="VVLAAVAEKTGYPVEILEPHMELEVDLGLDSITRTQVLAALRPMF
                     PQLEAVDRAQLAPLLTLRTVGEIADRL"
     aSModule        complement(27792..31046)
                     /complete
                     /domains="nrpspksdomains_HRD51_RS05875_PKS_KS.1"
                     /domains="nrpspksdomains_HRD51_RS05875_PKS_AT.1"
                     /domains="nrpspksdomains_HRD51_RS05875_PP-binding.1"
                     /locus_tags="HRD51_RS05875"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(28521..29369)
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS05875_PKS_AT.1"
                     /evalue="6.00E-59"
                     /label="HRD51_RS05875_PKS_AT.1"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="848"
                     /protein_start="565"
                     /score="191.8"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGAQYVGMGADLAMHLPQAHAVWNRHEVSRLVFPAPVFTDA
                     ERQAQRRALTDTGAAQPAIAAHSLALLAVLDAVGVRPDCVAGHSFGELVALHAVRAYDE
                     DTLMRLAARRGELMRGASGVMIALDTGVDEVSELLARHDLAEAWIANHNASHQVVVAAT
                     AEAGALVQRHATAAGMTARVLDTSAAFHSPLVASATEPLRAFLSGATVRAPLLDVYGNA
                     TAAVHPVEPAEIRRAIADHVTSPVRFADMVRAMHTDGVRIFLEVGPGGALTGLIKQSLA
                     AV"
     CDS_motif       complement(29016..29135)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS05875_0006"
                     /evalue="4.10E-10"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="683"
                     /protein_start="643"
                     /score="31.6"
                     /tool="antismash"
                     /translation="GVRPDCVAGHSFGELVALHAVRAYDEDTLMRLAARRGELM"
     CDS_motif       complement(29322..29372)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS05875_0005"
                     /evalue="2.50E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="581"
                     /protein_start="564"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FLFPGQGAQYVGMGADL"
     aSDomain        complement(29682..31046)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS05875_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="7.50E-122"
                     /label="HRD51_RS05875_PKS_KS.1"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="461"
                     /protein_start="6"
                     /score="399.2"
                     /tool="antismash"
                     /translation="IAIVGVSAITPGAPDVDAFWRNVIEGRDLMTDVPADRWLIEDFYD
                     PDPEAPDKTYARRGAFLPEVEFDPMALGVPPRNLPATDTAQLLALVAAERLLTGLAGTG
                     LDQVDGERVGVFLGCASLQLLGEMAARAGRPLWRRALLDSGLSEADADAVCDRIADYST
                     PWQEATFPGLLSNVVAGRIANRFDLHGANFTVDAACASSLAALSVAADDLLLGRSDLVI
                     TGGVDTLNDPLTFQCFSKTPALSSSGDCRPFDEHADGTMLGEGIALFALKRLADAERDG
                     DQVHAVIRGIGSSSDGSGTSVYAPLDTGQARALRRAYEAAGYGPETVGLVEAHGTGTAA
                     GDAAELAALRSVFDASGRADRQWCALGSVKSQIGHAKAAAGAAGLLKATLALRHRVLPP
                     TIKVTRPNPGLKLAESPFYLNTQARPWIHTADHPRRASVSSFGFGGSNFHVALEEY"
     CDS_motif       complement(29904..29948)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS05875_0004"
                     /evalue="3.80E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="387"
                     /protein_start="372"
                     /score="10.0"
                     /tool="antismash"
                     /translation="GSVKSQIGHAKAAAG"
     CDS_motif       complement(30012..30056)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS05875_0003"
                     /evalue="2.10E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="351"
                     /protein_start="336"
                     /score="10.7"
                     /tool="antismash"
                     /translation="VEAHGTGTAAGDAAE"
     CDS_motif       complement(30255..30287)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS05875_0002"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="270"
                     /protein_start="259"
                     /score="-2.6"
                     /tool="antismash"
                     /translation="DEHADGTMLGE"
     CDS_motif       complement(30432..30479)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_HRD51_RS05875_0001"
                     /evalue="4.90E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="HRD51_RS05875"
                     /protein_end="211"
                     /protein_start="195"
                     /score="12.7"
                     /tool="antismash"
                     /translation="GANFTVDAACASSLAA"
     gene            complement(31075..32610)
                     /locus_tag="HRD51_RS05880"
                     /old_locus_tag="HRD51_05740"
     CDS             complement(31075..32610)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978753.1"
                     /locus_tag="HRD51_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05740"
                     /product="PfaD family polyunsaturated fatty acid/polyketide
                     biosynthesis protein"
                     /protein_id="WP_235092465.1"
                     /transl_table=11
                     /translation="MSDTAPGVFHGDGLVELAQRVARPVHLVARERDGALGLSERPRPA
                     AVGTVPAMYPEWLGGRSFAETHQVRFPYVAGEMAYGIAGVEMVEAMAREEMLAFFGAAG
                     LGLARLDRDLERLRTGLAGRRNWGVNLIHQPHDRAMENEVAARLLRAGVPKISVSAFMD
                     ITPAVVRCSGSGLRADAAGRIFRRTALFAKVSRPETAELFLSPPPAELVRRLVRDGELT
                     EDEGRLAARTPVVDDITVEADSGGHTDGRPLVAVLPAVLALARRKNPGVRVGAAGGLGD
                     PAAVAAAFALGAAYVVTGSVNQMSVEAAVSDEAKAMLAQAGVADVAMAPAADMFELGAK
                     VQVLRRGTKFAGRAARLHQLYTAHPSLESIPKETRQALEREVFGTSLDDVWKLTEEYWS
                     QRAPAEVTRAHADPKHRMALTFRWYLGNAAAWAVDGAPGRRFDYQLWCGPAAGAFNTWV
                     AGSFLADPGRRSVTQIARNLLQGAAVLTRAHQLRTLGVRLPAEVFDFRPRPLA"
     gene            complement(32603..33337)
                     /locus_tag="HRD51_RS05885"
                     /old_locus_tag="HRD51_05745"
     CDS             complement(32603..33337)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_05745"
                     /product="hypothetical protein"
                     /protein_id="WP_235092466.1"
                     /transl_table=11
                     /translation="MVAETPKGNEETNATRRTVLRGAAGLAAGAVPAVALTGEAVAAPR
                     PDAAVTIAAAERLAAAQDPYLRRKQLWMFEVLDDDGDGAVTPGDTMQFAHRLARLTGHA
                     QDSPRAQQMVATVNRIWHALVVKPAWVPDPKRLDAEQFVVVMANSVAETPDKTLQYIGV
                     VTNLAFAMADDDHDGRVTRDEAIRLGTEVLRVDRNHAEHAWEVLDADADGHLGYAEVLM
                     AVTDFITSLDPRAPGNLALGRV"
     misc_feature    complement(33447..33463)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.95"
                     /tool="antismash"
     gene            33609..33911
                     /locus_tag="HRD51_RS05890"
                     /old_locus_tag="HRD51_05750"
     CDS             33609..33911
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="HRD51_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="HRD51_05750"
                     /product="hypothetical protein"
                     /protein_id="WP_235092467.1"
                     /transl_table=11
                     /translation="MKPLLRLFASPLLDILAAPNGVDRCLAAVNPLWSVSETRARVLHI
                     RHQARDTVTLTLQPNANRRGFCAGQHVRLGVEVNGVRRQTWTPSPPHSTWRLTAC"
     gene            33905..>34759
                     /locus_tag="HRD51_RS05895"
                     /old_locus_tag="HRD51_05755"
                     /pseudo=""
     CDS             33905..>34759
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020121349.1"
                     /locus_tag="HRD51_RS05895"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="HRD51_05755"
                     /product="IS982 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLKDSPHLAPWRPATGIAPRLTDAELVTLAMMQAMLGFTSEAKWL
                     RHARAHLRHLFPYLPKQPGYNKRLRKVAELLRRITRLLATDTSVWSDVWIVDSTPVECG
                     RSRETVKRSDLAG"
     gene            complement(34781..36280)
                     /locus_tag="HRD51_RS05900"
                     /old_locus_tag="HRD51_05760"
     CDS             complement(34781..36280)
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1122: ATP-dependent
                     RNA helicase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985583.1"
                     /locus_tag="HRD51_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05760"
                     /product="DEAD/DEAH box helicase"
                     /protein_id="WP_235092468.1"
                     /transl_table=11
                     /translation="MNRTARSKDRPFRSRFADSGRGGRRSQPSKRSGGNRRRPAARPGE
                     FAPPVTHTPALPPAETFAELDMPPALLASLAAEGVSVPFPIQAATLPNSLAGRDVLGRG
                     RTGSGKTLAFGLALLARTAGRRAEPGRPLALILVPTRELAQQVTDALTPYARSLNLRLA
                     TVVGGMSIGRQVSALRGGAEAVVATPGRLKDLIERGDCRLNEVGITVLDEADQMADMGF
                     MPQVTALLDQVRPEGQRMLFSATLDRNVDLLVRRYLTDPVVHSVDPSAGAVTTMEHHLL
                     HVHGADKHATTTEIAAREGRSIMFLDTKHAVDKLTKHLLKSGVRAAGLHGGKSQPQRTR
                     TLAQFKTGQVTVLVATNVAARGIHVDNLDLVVNVDPPSDHKDYLHRGGRTARAGESGSV
                     VTLVLPDQRREMDRLMADAGITPQSTKVRSGEAALSRITGARTPSGIPVTITTPVVERP
                     KRGGFSTRGRRTRSAQARRSAGAPRTGTPASGRQSSRGAAA"
     gene            complement(36557..36760)
                     /locus_tag="HRD51_RS05905"
                     /old_locus_tag="HRD51_05765"
     CDS             complement(36557..36760)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125862.1"
                     /locus_tag="HRD51_RS05905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05765"
                     /product="cold-shock protein"
                     /protein_id="WP_037915390.1"
                     /transl_table=11
                     /translation="MATGTVKWFNAEKGFGFIEQDGGGADVFAHYSNIATQGFRELQEG
                     QKVSFDVTQGQKGPQAENIVPA"
     misc_feature    complement(36716..36727)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.36"
                     /tool="antismash"
     misc_feature    36792..36806
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.63"
                     /tool="antismash"
     misc_feature    complement(36920..36935)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.47"
                     /tool="antismash"
     gene            37310..38271
                     /locus_tag="HRD51_RS05910"
                     /old_locus_tag="HRD51_05770"
                     /pseudo=""
     CDS             37310..38271
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044031.1"
                     /locus_tag="HRD51_RS05910"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05770"
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVRRHELTDEQWQKIEALLPANGKPGGQWADHRTVINGVLFRART
                     GVPWPDLPERYGPWQTVYERHRRWSADGTWQQILTELQIEADATDPDGTLAKDVAKDGV
                     PRRREWAVNIDSTSCRAHQHAAGARRRPPRDFPQKGAVRVWTQRGVRRWGAHEAD"
     misc_feature    37361..37363
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    37553..37555
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    38318..38332
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.39"
                     /tool="antismash"
     gene            38487..38834
                     /locus_tag="HRD51_RS05915"
                     /old_locus_tag="HRD51_05775"
     CDS             38487..38834
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155339.1"
                     /locus_tag="HRD51_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05775"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_205362102.1"
                     /transl_table=11
                     /translation="MTRETPSRATDRFDDDDYPAYTMGRAAEMIGSTPAFLRAVGEARL
                     IVPLRSEGGHRRYSRYQLRIAARARELVDQGTPIEAACRIVILEDQLEEARRLNEELRR
                     TAADPSQPTGP"
     gene            39688..40206
                     /locus_tag="HRD51_RS05920"
                     /old_locus_tag="HRD51_05780"
     CDS             39688..40206
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1229: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024954.4"
                     /locus_tag="HRD51_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05780"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_205360206.1"
                     /transl_table=11
                     /translation="MAGPLWVELSSEDEAELGRRLRARDLPVNERVRLECVRLSAQGRN
                     APEIASIVDRHVVTVRKALRRFLDGSFEALADAPRSGRPPRWTREDLDALEAMLDTAAA
                     EGTTWTLPALAEWLRRERGVNVDSSWLSVLLHRDGFRWKRTRDSLRHKAGPALQAAAWE
                     RLEGLRLYG"
     gene            40170..40799
                     /locus_tag="HRD51_RS05925"
                     /old_locus_tag="HRD51_05785"
     CDS             40170..40799
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024751.4"
                     /locus_tag="HRD51_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05785"
                     /product="transposase"
                     /protein_id="WP_205360203.1"
                     /transl_table=11
                     /translation="MGAAGGPTAVRLRAEAGTEDLYYLDESGFSPTLPTGFTWARTGVR
                     AVVKREDTKNRRVNVLGALSESGPGPELVWRAVDHKIDASMVLDFVCTHIARLPKGTDS
                     LTDPPPGWRRVRPCTIVMDNAQIHHARLFKGRREELEAIGVHLFYLPPRSPELNLIERI
                     WRSVKYQDMPVRAYTSTTALHTAVDQAMTRRATALTPTTEDLLKTA"
     gene            complement(40882..41598)
                     /locus_tag="HRD51_RS05930"
     CDS             complement(40882..41598)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146428.1"
                     /locus_tag="HRD51_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_235092469.1"
                     /sec_met_domain="PEP_mutase (E-value: 4e-24, bitscore:
                     84.4, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLHTRTIPAERRRALRARLATGRLLPMPGALNPLSARLIQDTGFE
                     AAYLSGAVLAADLGLPDIGLTTSTEIAARAQQTTRATDLPVLIDADTGFGEPLNAARTV
                     QLMEDAGLAGLHLEDQVAPKRCGHLDGKSVVPREQMDQLAEVLREEAGRWQEAAVLGEY
                     CDALERRLAEPGSVVDEPALESARRWLEWAREFVCAISPLNRRPEMPTPREPTPDELKA
                     HMNGWSPYGPERRDRR"
     gene            complement(41598..42627)
                     /locus_tag="HRD51_RS05935"
                     /old_locus_tag="HRD51_05800"
                     /pseudo=""
     CDS             complement(41598..42627)
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981009.1"
                     /locus_tag="HRD51_RS05935"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05800"
                     /product="MmgE/PrpD family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAPAPDRTARHPPGSPALEHHVRVHPQRRPTAPRGPTRLEARAGR
                     HRHRGAGLRQRRHGRQPGHRQRRGRRRRPAAPPGRRRRRPRPGPGPPDDRPRRLGPRHR
                     RPGLPGVGRLGQRHRRARVGLPRHVPGRRLLPPRRQRPAPARRRPAHRPHRRRPAPWDR
                     RRLRDPRRPGQGHLPARAPHRPRGPPRRRHRLRAGGRHLAPRALLRPGPRPPTGDGRTL
                     AADHHGRGPGVDPPLPRARSGPPRLRRPGRGHPRRRHRRRGRTGRRRRPSGRGPPLPPA
                     RLRGQVPHPDRGDPRPRRPNALPRHGGTARRPGRRRSRRAVPGRRHRGRHRARRPPAEG
                     PVL"
     gene            42772..44008
                     /locus_tag="HRD51_RS05940"
                     /old_locus_tag="HRD51_05805"
                     /pseudo=""
     CDS             42772..44008
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982012.1"
                     /locus_tag="HRD51_RS05940"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05805"
                     /product="short-chain fatty acyl-CoA regulator family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MARRAAGRKVYARARLRRLRREHGMNQVDKARALGISTSYANQIE
                     QSQRPLTAPVLLRIAEVFGVDAEFFSEAAEDRLGAELRAALADEACGVPMPAFEDITEA
                     ARDHPEVARALVALHHRYRDAAEQAAALAAPGTDARRAPAEPHDEVRDFFYAHHNRFGP
                     VDDAAEHTAGALGLRPGRAVDPLTARLAERHQITVVQAAAGHSPDARRFDPTTGVPFLS
                     RWLSDGQRAFQLATQLALLEHGSLLDGLAGGALELTSPESTALARSGLANHFAGALLMP
                     CSAFHGVAEEVRYDIELLSARFGVGFETVCHRLSTLQRTGHHAPRAEFAVALGCELRHA
                     HRLVYAEGVALDDPRAATPIGLGCRICERRDCPQRARPPARPARHRPRPAHLRAVSRGR
                     TQCHARSRRSHRV"
     gene            44005..44595
                     /locus_tag="HRD51_RS05945"
                     /old_locus_tag="HRD51_05810"
     CDS             44005..44595
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564514.1"
                     /locus_tag="HRD51_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05810"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_205362104.1"
                     /transl_table=11
                     /translation="MTSRITLISPAIGPSLRQGRFDDGGPLDAVGAAQARAAAGALPAA
                     GRVCVSPSVRCRETAAALGLDGGPSGPELAGLDVGRWSGRTLDDVAAAEPEAVARWLTD
                     PGAAPHGGESVRDLCGRVARWLDACGRADGRTLAVVEPEVVRAVVVHVLGAPEEAFWRI
                     DVPPLTATEVSGRSGRWNLRLGRALVADAEPDS"
     gene            complement(44623..44898)
                     /locus_tag="HRD51_RS05950"
                     /old_locus_tag="HRD51_05815"
     CDS             complement(44623..44898)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952867.1"
                     /locus_tag="HRD51_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05815"
                     /product="hypothetical protein"
                     /protein_id="WP_039638688.1"
                     /transl_table=11
                     /translation="MARTPQPRHITLGGRAAVALTPEEYEQLIASRRQIGGQSARVRVL
                     AQQVKRTERLLSELEALVGGPDDRTDTDRLRRAIAELLRRHRDEAH"
     gene            complement(45063..45815)
                     /locus_tag="HRD51_RS05955"
                     /old_locus_tag="HRD51_05820"
     CDS             complement(45063..45815)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192299.1"
                     /locus_tag="HRD51_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05820"
                     /product="CbtA family protein"
                     /protein_id="WP_235092470.1"
                     /transl_table=11
                     /translation="MNSATVRNLLVRGMLAGLGAGVLALVVAYVLGEPSVNSAIGFEEA
                     HSHEHEMEVVSRTLQSTAGLATGVLVYGVAFGGIAALAFCFALGRVGRFGPRATALLLS
                     GTALLAVYVVPFLKYPANPPSVGAPDTIGKRTTLYFLMMVLSVLLAVAATQLGKRLVPG
                     LGTWWATVVAVAAFVVVIGLAYQFLPVVNEVPKDFPAALLWRFRLSALAVQAVLWGGFG
                     LLFGELAERQLHPAPARASSGHTVPASN"
     gene            complement(45837..46058)
                     /locus_tag="HRD51_RS05960"
                     /old_locus_tag="HRD51_05825"
     CDS             complement(45837..46058)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014045240.1"
                     /locus_tag="HRD51_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05825"
                     /product="CbtB-domain containing protein"
                     /protein_id="WP_039638686.1"
                     /transl_table=11
                     /translation="MAQTVAQPTSTTPVVPATLPLKAIAPWAVFFGVLMLVLLYFVGAE
                     QGATSVFSGTDVHEWVHDARHLLGFPCH"
     regulatory      complement(46095..46249)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(46122..46137)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.93"
                     /tool="antismash"
     gene            complement(46313..47104)
                     /locus_tag="HRD51_RS05965"
                     /old_locus_tag="HRD51_05830"
     CDS             complement(46313..47104)
                     /EC_number="4.2.1.17"
                     /NRPS_PKS="Domain: ECH (16-255). E-value: 7.7e-72. Score:
                     233.5. Matches aSDomain:
                     nrpspksdomains_HRD51_RS05965_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008409089.1"
                     /locus_tag="HRD51_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05830"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_235092471.1"
                     /transl_table=11
                     /translation="MTTPTTDGYETILVERTGRTALLTLNRPKALNALNLRLMNEVVAA
                     TEALDRDPECGCIVLTGSARAFAAGADIKEMQPQDYPEMYLSDWFAAWDRLGRLRTPTV
                     AAVSGYALGGGCELAMLCDVLLAADTAVFGQPEIKLGVLPGIGGSQRLTRAVGKAKAME
                     MCLTGRTMDAVEAERAGLVSRVVPADELRAEALAVAGTIAGMSRPVAMMVKEAVNRSFE
                     TTLAEGVHFERRIFHAAFALADQKEGMTAFVDKRPPRFTHR"
     aSDomain        complement(46340..47056)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS05965_ECH.1"
                     /evalue="7.70E-72"
                     /label="HRD51_RS05965_ECH.1"
                     /locus_tag="HRD51_RS05965"
                     /protein_end="255"
                     /protein_start="16"
                     /score="233.5"
                     /tool="antismash"
                     /translation="TGRTALLTLNRPKALNALNLRLMNEVVAATEALDRDPECGCIVLT
                     GSARAFAAGADIKEMQPQDYPEMYLSDWFAAWDRLGRLRTPTVAAVSGYALGGGCELAM
                     LCDVLLAADTAVFGQPEIKLGVLPGIGGSQRLTRAVGKAKAMEMCLTGRTMDAVEAERA
                     GLVSRVVPADELRAEALAVAGTIAGMSRPVAMMVKEAVNRSFETTLAEGVHFERRIFHA
                     AFALADQKEGMTAFVDK"
     gene            complement(47101..47997)
                     /gene="mmsB"
                     /locus_tag="HRD51_RS05970"
                     /old_locus_tag="HRD51_05835"
     CDS             complement(47101..47997)
                     /EC_number="1.1.1.31"
                     /GO_function="GO:0008442 - 3-hydroxyisobutyrate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006574 - valine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mmsB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100009.1"
                     /locus_tag="HRD51_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05835"
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="WP_235092472.1"
                     /transl_table=11
                     /translation="MTTTLAFIGLGHMGGPMAANLVRAGHRVRGHDTAPEQLAAAATAG
                     VEPAGSAARAIAEADAVFTMLPAGRHVLDLYQDVLAAARPGTLFVDCSTVAVADARTAH
                     DRAAAAGMRMLDAPVSGGVVGAEAGTLTFMAGGGPDEFAEAEPLLAAMGRKSVHCGGPG
                     AGQAAKICNNMILGISMIAVSEAFVLGESLGLTPQALYDVAATSSGQCWALTTNCPVPG
                     PVPTSPANHDYRPGFAAPLMAKDLRLAADAARSGGVRTELGLRAAELYQEYAQGAGAEA
                     DFSGIVRDIRQRSGGQA"
     gene            complement(47994..49076)
                     /locus_tag="HRD51_RS05975"
                     /old_locus_tag="HRD51_05840"
     CDS             complement(47994..49076)
                     /NRPS_PKS="Domain: ECH (12-309). E-value: 6.7e-34. Score:
                     109.2. Matches aSDomain:
                     nrpspksdomains_HRD51_RS05975_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564520.1"
                     /locus_tag="HRD51_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05840"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_205362113.1"
                     /transl_table=11
                     /translation="MTGTDQRPVVREVRGRTARLTLNRPRALNALTHPMVRALDQALTD
                     WEHDPAVETVVLTGAGERGLCAGGDIRAIHDDARDGDGSASAAFWRDEYRLNARIARYP
                     KPYVALMDGIVMGGGVGISAHAAVRIVTERSRIAMPETGIGFVPDVGGTYLLSLAPGEL
                     GTHLALTGTQIGASDALLCGLADHYVPSAALPALLDDLAAPPLREVLHRHVVRQAPPGR
                     LADQRPWIDACYAADTVEEIVGRLSDHGDPAAKEAAGTLLAKSPTALKVTLTALRRARH
                     LGSLEAVLDQEYRVSRAALAAPDLVEGIRAQIVDKDRNPHWSPPTLAEVGDTHVARFFA
                     PLGAEELGLAPSGTTQEVPW"
     aSDomain        complement(48150..49040)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_HRD51_RS05975_ECH.1"
                     /evalue="6.70E-34"
                     /label="HRD51_RS05975_ECH.1"
                     /locus_tag="HRD51_RS05975"
                     /protein_end="309"
                     /protein_start="12"
                     /score="109.2"
                     /tool="antismash"
                     /translation="VRGRTARLTLNRPRALNALTHPMVRALDQALTDWEHDPAVETVVL
                     TGAGERGLCAGGDIRAIHDDARDGDGSASAAFWRDEYRLNARIARYPKPYVALMDGIVM
                     GGGVGISAHAAVRIVTERSRIAMPETGIGFVPDVGGTYLLSLAPGELGTHLALTGTQIG
                     ASDALLCGLADHYVPSAALPALLDDLAAPPLREVLHRHVVRQAPPGRLADQRPWIDACY
                     AADTVEEIVGRLSDHGDPAAKEAAGTLLAKSPTALKVTLTALRRARHLGSLEAVLDQEY
                     RVSRAALAAPDLVEGI"
     gene            complement(49073..50221)
                     /locus_tag="HRD51_RS05980"
                     /old_locus_tag="HRD51_05845"
     CDS             complement(49073..50221)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003952195.1"
                     /locus_tag="HRD51_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="HRD51_05845"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_205362114.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.9e-26, bitscore:
                     91.8, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 7.6e-25, bitscore:
                     85.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 3.2e-47, bitscore:
                     159.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTQLSEDQLALVETTLDFAQDHLAPHAVAWDRDKHFPLDVLRK
                     AAGLGLGGVYVREESGGSGLGRADGVLVFETLASGCPSIAGYLSIHNMVAWMVDHYGDA
                     AQHERWLPRLCAMEDLGSYCLTEPGAGSDAAALRTRAVRDGDDYLLTGVKQFISGAGAA
                     QLYVVMARTGDDGPRGVSAFLVDKDDAGLSFGANERKMGWNAQPTRQVILDGVRLPADR
                     LLGHEGQGFRIAMNALNGGRLGIAACSLGGARSALDSSLVHLADREAFGGRLLDAPALR
                     FRLADMATELAAARALVHQAAQALDRGDPQAPQLCAMAKRFATDTGYAVADRALQLHGG
                     YGYLSDYGIEKIVRDLRVHQILEGTNEIMRVIVARGLTEALR"
ORIGIN
        1 gccattgtcc cctgaacacg catggggccg gtcgccctgg acgtccacgt ccaccacgag
       61 cccgttcgcg gcggcgacct gtccggcgag ggaggtgacc gactcggcga gccccagccc
      121 ttggacggct gccgggctca cggtggcgat gatgcggcgc agcgtgccgg cctgttcgtc
      181 gagggtgcgg gacgcgtcct ccatcgccgc acgcagcgca ccgggatcgt ccagtgcgcg
      241 ggccgcgtcg agccgccgct gggtcagtgc cagcaactgg aggacttcgt cgtgcaactc
      301 gcccgcgagc aggcccgcat ggtgctcctg ccgttccacc atggcactgg cgcgtccccg
      361 gctgaggacc accttcacct cgggccaggc cggaacggcg tacacggctg cggccagcag
      421 gaacgtcatg gccgcgtcgt ccatcggtgc ggagtgcgcc agccggtcca cgctcaggac
      481 cgtgaatccg cagcagatca tgatcagcag ccggcgggcc cgccgcagcc cgcaggtcag
      541 cagcgcgagg acgccggtgg ccagggcgac gctcggggcc gagaccgacc ttggcggcaa
      601 gtggccgtcg gtgaggaggt tggccgtgta ggacacgacg ctgaccaggc tcaccgcaat
      661 gcacaagccg ccgagtgtgc ccagggcgag cgactgttgc gcggtggccg gccgggcggt
      721 tccgctacac atcggcggag cggttctgcc gggcgtacgc gacgaggtcg gccctggtga
      781 ccaggcccag ccgggcgcgc agagcggccc tgacgctctc caccgtacgg acgctgaccg
      841 tcagccgcgc ggccacctca cggttggtgt gcccctcggc gagcagaccc aggacctgcc
      901 gctcccgcag ttgcagttcc ggctcccggc cctgggtacg ggccagcccg gcaccgagcg
      961 agggctgtac gtaccgttct cccgacgcca ccgtccttac cgccaggacc agttcggaca
     1021 cgggactgct cttcagcaga tagcccgcgg cacccgcggc cagtgccccg cagatgatgg
     1081 cacggtcctc gtagcagctc tgcacgagaa ttcccatctc cggtgcggcg gcgaggaatt
     1141 ggggaatggc cttgagcgcc agccccgact ccagcttcat gtccagcatc agcacatcgg
     1201 gctgctgctc ggaaacgatc tccaacgcct cgcgttcgca ggcggcctcc ccgaccacga
     1261 tgaagccctc aggctccagg aacgcccggg ttccagctcg tacggtcgga tgatcctcgg
     1321 ccaggaccac tcgcacggga cccccttctt ctgcacagcc tttcaggcat ggggaaaaca
     1381 tggcttcttt gtcgccccag tgaatgcatt caccttccga tgcagtggcc aatcttgtca
     1441 accgacggaa ttcccgcggc ggacggctaa aagttcaatt tcctgcggct gacccgcaga
     1501 aatcttgcgg gcttctacgg attttccgca gcgggcgggg cggtggcgat cgcttcatcc
     1561 gaatcaccca ccggacaccc ggcgatcacg agaaagaaag agttccgaga tgttctccac
     1621 gctcttcgac atcgcaacca gcctcaccaa ccacgcccct agcggttcca gcaccaggat
     1681 gccatggctt ttcatgatga ttgcgctgcc tgtcccgaag agcccgtaaa tcccgtcttg
     1741 acggggaaat gtgccaccga tgaagaagga aggcggacac ggatgactcc gttcgccttc
     1801 gcggtgaacg ccttcgcctt agcgatcaag tggatcttca gttgagatcc gactgttccg
     1861 aacgtgaatg cctttcgccg gaagagagca cactaaccct cgctcccatc cggtccctca
     1921 tacccacgta acgcacagca catgactccc catcaaaagg gcgtcccggt aacgcgacct
     1981 ggaggaaatc cgagctatcc ctcaccggtg tccgggcgcc acggggcccg gacaccggcc
     2041 acgaggcacc ggacaatctc gcgccgggtt tgaggcgacg gtactgccga ctgcccgagg
     2101 aacgctccac agggctgacc ccgcacagcg cgacgaagga cgcctcactg cgcaggcact
     2161 ccgggttgtc ccccacaacg atcgtccaca ggcgatggaa tcccgaaatg aagcagcaca
     2221 gcctgcgccg ccaaccggtg acaggtagga aagacacaga cggacgagag gaacgacctg
     2281 acatgcaggt cgcagtggat ttcaaccgat gccagggatc tgcccagtgc gccatcctcg
     2341 ctccgtccgg gtccgagccg cgcgacgacg aggccctggt gtacgccccg cccgtcccgg
     2401 acggccgacg caaagcatct gctgcgcgcc gcggcggctt gcccggtgcc ggtcaagagt
     2461 ggcccgaagg gcggccggat cggtcgtcgc cggcgcctcg ccggcagggc tgcagaccgc
     2521 cggaacaccg cgcgaggagg gcttcgacgg cgggccggcc atcgtcgggg acgtgctcca
     2581 ccgcccgtac gaccggccgc cgttgtccag acaggtgctc tgctcggcaa ggcatgcgcg
     2641 gaagactgcg tccttcccgc ccaccgcgga ccggcccccg caggcaccag cccggctctg
     2701 cgcggctccc gctgcctgtc cctcgcccag gcacccgact gctggaagct gtgaccaggt
     2761 gattcaccgg ttcgggccgt caaggacccg gctgctcctc ctcaccatgc gagatcagcg
     2821 agacgtaggg gtgcgggccg cagacgagct ccggtggcac ggctccaggc ccggaaccga
     2881 ggtgaggctg atcctttgga gtggacaccc caacgccgtt gatttagtgg cgcgagcggt
     2941 ttgtcaaggg ggcttgaggt atgcaacgga accccggtag atcaacgttc ggccaagagc
     3001 actgattagg gggtttcgtt gctggaccag tctgtcgttc cccgtgaagt ccgggcagcc
     3061 gagggcgtgt tcgcccccga tcatctcggc gaactgacgt aggtggtgga ctttgccctg
     3121 gtggacgcgg tgctcgaaga ggccggggcc gtccagcgtc gggtacggat gctgccctcg
     3181 cgggttgtga cgtacttcgt gctcgctctc gcgttgttcg agacctgctc ctatcgggtg
     3241 gtgtggggca agatggcggc aggtttgagt agcctcgacc tggcccggcc aagtgcctcg
     3301 gctctgtgcc gggcccggcg ccgtgtggga accgagccgt tccgactgtt gttcgagatc
     3361 ctgtgcgggt ccctgggccg gccggacacc cccggctgct ggtggcgtgg actgcgcctg
     3421 gtggcgatcg acgggacgca cctgcacatc cccgactccc aacacaccgc cgcgcgcttc
     3481 cccaagcgca tcggtaagag caggagtgcc ttcggctatc ccctgctgcg gctgtgcacg
     3541 ctggtggaat gcgggacccg cgcgctgctc ggggccgcct tcggccccga ggaccagccc
     3601 gagaccgcct atgcctcccg cctgctggac aagctcaccg gccggatgct cgtcctgctg
     3661 gacgcaggct tcgacagtgc cgacttcctg ctcgaactgc aggacactgg cgcccagttc
     3721 ctgtgccgct ctggcgccag ccgcaacccg ctgatccacc ggcgactgcc cgacggctcc
     3781 tacctgtcca tgttcagaca gcacaagaag ccggtgcggt ccaggggccg gttctgccag
     3841 tcggacatgc cctccatcac cgcgtcggtg atgtgggaga tcgtctgctt ggagacctca
     3901 gcgccataca cctcggccag acgggccgcg atctcgccgt gcgtgagccc cttcgcggac
     3961 agggacagga ccatctcgtc gacgccggtc aggcaccgct ggcgcttctt gacgatctgc
     4021 ggctcgaacg agccctcccg gtcccgcggc acctcgatct cgaccgggcc gacgtccgtc
     4081 aggaccgtct tggaccgttt gccgttccgc gagttgccgc cgttcttgcc ggctgggtcg
     4141 tgcttgtcat agccgaggtg atcagttatc tcgccatcga gcgcggactc cagcagccgc
     4201 ttcgtcagct gctgcagcag cccgccctcg ccggtcagct gcaatccatc agcctgggca
     4261 caggcgacga gctcctcgat gaacttctca tccgcagatg tcgacgctgc cgcctccatg
     4321 gccgccgccc cgaacgtctc ctcggctatg ttctcgctgg tcacaggtgc aatcctccat
     4381 gatcggagtt acaccgttct atttaccgtc cccgcggcct cagacccgcc gggggtctga
     4441 ggccgctgtc ctgtcggggt tggacgatcc ggtcaggagg cggggccgag gtccttccag
     4501 ggttcgtggt cggcgtcagg gccggtcccg ggggcgttgt tctgggtcca ccacttcgcg
     4561 cgccagtagt ggccgttgta cttgacggtg acgtcttcgt gtgactgtgt ggccgggtcg
     4621 tatgccttgg cggcgtccca gtcgggggcg ttgcagccgg tgtcggtgac ctcgccggca
     4681 tcctccgcgc cgcgccggtt gtccgaggcg aggccgtagg tgcccccgga ggtggtcaag
     4741 gtggcgttgg ccgggccggt gatcggcaga tagtacttga tcgggatgtc gatgctcttc
     4801 cctgcgggta tcacctgaca gtattcgatc ttggtggtga cgcggtggaa gtcgcccttc
     4861 aggccggttc cggcattggg gcccgtgtgc ccgggagtga gtctccacag gccgtcgggg
     4921 gtgtcgctac cctgccagtt gccgtctttg accagcggtg aggtcgaggt cgggatgtcg
     4981 aatgagagtt ccgcaccgcc gccgatcgct ttgcccgtgt tgttggtgag gcggaccttg
     5041 ggctccaacg ggtacagctt ggccgacccc gccgggtagt cgaccaggtc gacctcaagg
     5101 ttcgcggtcc gggcggggag ttgggcggtg cttccggcgg cacgggagtt tccgtagtca
     5161 ccggcgtggc cgagtttttc gtccaggcgg ctggtcatgg tgtagccgat cccgcacggg
     5221 ttttcggcgg tgggggtggc agggcaggaa tagtcgccgg ccagctccca gatcatgacg
     5281 ccgccggcgc cgctgcgggt gacgtagtcg gcgaccgcat cgacggcctg ggtgtcggtg
     5341 gtcgacagga aggtcttctt ctgctcgttc cacagccacg acgtcttggt ggtgtcgtcc
     5401 cagtgccggg cgtagttgcc ggtcagcctg tcggatgcgt tgcgctcggg gtccagcccc
     5461 acctgggagc cgtagttcgg ctcgatgttg gcctccaggt tcttggcgtg ccacatcggg
     5521 ttggtgccgg ccggcaactc gccgccggcg ttggtggtgt cgtgccagat gttgtcgatc
     5581 ccccgggcgc cctccccgca cggtctggtg ccgggcggcg cgccgggccc gctaccggtc
     5641 ccggccgggc actgggactg gtcgggcatc ttcgaggtgc cccacatgcc ctggttgcca
     5701 ccggacacat cgctccaccc gcgggtgtag taggggatgc cgatgttgat ccggcccgcc
     5761 tgcaacgcgc cgcggaagtg cttgaacgcc cagtcggtgt tgaagtaccc gatgcctccg
     5821 tactccttgg tggagtacac cccggcatcg gccagctcgg tgtccttgcc gtcgtcgtac
     5881 agcggggcgt tggggccgac atacccgttc caggtgccgt ggaagtcgta cgccatcacg
     5941 tccacgtagt cctggtactt ggccgggtcg tggttctcca tcccgcgcac cagatacccc
     6001 gaggaggaca cggccgagga cagcaggtag tacgtgccgt cggctgcgct ggcccggtcc
     6061 agcttctccc gtaacgtctt catcagcttg ccgtatccgg ccatcagctc cccacgcacc
     6121 gggttggaca ccggccagtc ctcggggttt ccggtgttct ccagcgacgt cgggtactcg
     6181 aagtcgatgt cgacgccgtt gaagtggttc tgccggatga actccaccgc agagtccgcg
     6241 aacgtgtcga tcttcgactg ggcgtcgctg ccggtcacca gcgtgtagag cccgcgggtc
     6301 tgggaccaac cacccaccga gatcagcgtc ttgacgcgtg gatgctcggc cttctgctcg
     6361 ttcagcagtc ggatgttctc cacgtcctgg tcgccgatcg ccagtttgtt gtcggtgacg
     6421 tgtgcgaacg cgtagttgag atgcgtgatc tggccccagg ggacgttctg cggccggtag
     6481 gccgggcttc cgtccttgcc ggtccgccat ccggcgaagt atccgatcac ccgccggtcg
     6541 tgggtcttgc ccatccattc ccggccctca ctggtatagg cgaggcagta cggcgtattc
     6601 acacccggcg tgcgcggcat cccgtccgga cggcacttct cgttgtcgtt cgacgctccc
     6661 ggcggcggcc cgatcctcgg ctccccgtca cgcggcacgg ccgcgatccc cacccgcccg
     6721 ttccgccgcg gcgggggctt cagcgtggca atccgcctgg caatgtccag gtaggagagg
     6781 aagtagcgaa acgtgtgtcc gtgattggtg ttttcgaagg tgcgcctctg ggtgaactct
     6841 gttccctcgg ccctggggtc gttctgagcg gcctgccgga tatcgttgga caggtcggcc
     6901 cagttgtgga tcaggtactc gacccaggtg tccccggcac gcgttgcgtc caggtggaac
     6961 gtctgctgcc cgccccgcat cgcctgggcg atacgaccgg cgaagatgcc gaacctggcg
     7021 ccctcggcga tcggcatgat cacgtgctcg aaagactccc gcaggtcgtc cagggtcctg
     7081 ccgttgaaat ctgcgatata ccgcaccgca ttgcgcagcg gtgttgcacc cagctcgata
     7141 ccgaaaactt cgcggtatct ctcggagaaa gacaggggca cccgccttag attccgagcg
     7201 agggaattct ggacgtcctg cgggatatag acttccccgg tggtatgacc gtcgtgggta
     7261 taggcataca gcacgttccg agcccgtacg tagatgcccc ggacgtagag gtcgctggga
     7321 tcgatgacca gttgcaccgc gttctggtcc aggcccccga gagctccgat gccgatgatc
     7381 tgccagttcg gctgctgcat cacccgcccg acgcccggag tgtccgcgac gggctgggct
     7441 tgcccgttgc cgttccgggt catggtgttg cgcagattcc cgacgatctc cagataccgg
     7501 tccgccgtct catgcccgtc atcctgctgg gtgcggggct gcgtgggtgt ggctgcctgc
     7561 gcgataccgg gtcccgagct cacggccagg gacaccagca gggcaccgat cacagcccac
     7621 gtcgcgccgc gccacctcgc cccgcgccgc cagacaggca tgcgggaacg gtgtctcacc
     7681 atttcgaggc tcatgtggtc acgcccagaa ggtgtaggtc gcgcgcagtg ttccgttgct
     7741 cgaggccccg ccgtccgagt agtaggcagc cgtgtattcc ttgccgtggg tcagttttcc
     7801 ggtcgcgatc accgtggcgc cgaacgcttc cccgcattgc tccttgtagt cggagctggg
     7861 gcaggtccag tcccagtaga cgcgcgtacc cttggtgccg ttcccctcgt agatgccgat
     7921 ccagtcgttc ttgtgcttgt cgtaggcggc gcgatcactg gggatctgcc agatcaccgc
     7981 gacccccata tccgtgagcc ggaacggcgg ggccgggacc gtcttgtacc aaactcgcga
     8041 agtggtgacg gtggtgttga cgatcgagta gtcggtgttg accgtcccgt cgtctgcgtc
     8101 ggcgagtctc ggcgaccgct gcgaggtcag ccgccgcgcg tccgcctgtc tgtccttgcc
     8161 ggccggaccc ggcgcagtgt cagcgaccgg cgtcacgctc accgctgccg gatgtgtacc
     8221 tgatgctgcg tcagcagcgg ctgtcagtgc cacagttgcc agggcagcgg ccagtccggc
     8281 catcaccgcc gtggcacgcg aacggagcct cgtcagacgc atggatggtc ttcctctcag
     8341 cgagttgaaa accggctcct gccgcgtgtc caccatccgg agcgcgcctg ggacaacgtc
     8401 acacaaacac gccgaggaca tgacaatatc gtggccgaac ccgaggctca acgtcctgcc
     8461 gccgagcccc taccagtccg ccagaaaacg atgaatttcc tataaacgat gaatcaacgc
     8521 ggcgtcgggc gacatcacgc atatctcagt catccgcacg gcatcgcacg ccggctgcgg
     8581 ccatcacagc gacagggcac acgccaccga cgcccgtgaa gggcataccg ccgatgtacg
     8641 ggtgcacgcg ctccgggccg ggttctccgg cccgcggcag cagtacggcc cgcggtgacg
     8701 gcagtgccgg tgcttcgcgc gctcgcggtg cggggaaccg gaagccgacc accttcggag
     8761 gcgaacaccc atgcaagaac agcgagttga cctggtgacg ggcggaggaa cgggaatcgg
     8821 ggccgccacc gcccggctgc tgcgcaccgc cgggcaccag gtcgtgatct ccggacggca
     8881 gcccgagcca ctgcgccggg gtggccgagg agaccggagc gctggcccac ccttccgacg
     8941 ccgccgcccc cgaggccgtg cgcgagctcg tcgagacgac ggtgacgacc tactggagac
     9001 ttgacggggt ggtgctcaac accggagtcg ggcggggcgg cgcggtcggc gacaccgcgg
     9061 tcgaggactg ggaagcgctg atacggacca acctcacggg cccggcttcc ccgccgacct
     9121 ggtggctgct cagcacgagc tcagccagac ccgtaccgcg taccaacagc tctgcgcccg
     9181 tctgccgtgg agcgccgagc cgcactccgg gtggaacgac acctcgcccg cggtcacgcc
     9241 cggccgatcc gtgccgagca cctgaagctg ccggccgagc tggaggccaa gccgcgccgc
     9301 tgcgtcggcg ggtggtcgcg gcgaccaaca aggtggagtc gttcaaccgg ttctcccagt
     9361 ggatcggctt cggcaaccgc ggtgccaccg ccgacaacga ccccatcgag caggagaagg
     9421 cgatgaaatt caacgcactc gtctcctcca ccgcatggct cggtcaccgg agcccggagt
     9481 ccactcagca ctacgccaag atcaccccga acacgctggc cggggcctac aacgacgccg
     9541 gatacttcga gcgcaacgtc cgcaccatcg aggtcctggt cgaccgggac gcggtcacct
     9601 ccgaagccgc cgcctcagga gagccgtggc agtactacga cctcggtcac gggttctgca
     9661 cctacacgtt cttcgagcag tgcccccacc gcatcgcctg cgcccgttgc gacttctaca
     9721 cgcccaagac ctccagcaag ggccaactcc tggaggccaa ggacaacctc cagcgcatgc
     9781 tggcgagcgt cccgctcagc gacgacgaac gcgccgcgtc gatgcggcca gaggccgcgc
     9841 tcgaccagct gctggaacgg ctggtcgacg ttccaacgcc gaccggtgcg acagcccgcg
     9901 agatcggcgt tcctgctacg gcgacgctcc taccgatcgt cgccgtcaac cagggcaaag
     9961 gctgaactac ttgataaatc ggattccgca gaccgcgggt tcactgggat ctcgcgccgg
    10021 tggacgatcg cgcgcactca tgaccttgag ccaaagggga taggtaaagg tagggggcgc
    10081 gatggtcagg tcgattgtga tggacggggg cgatggtgct gcggtggggg tgcatggtca
    10141 tggtcgcctc ggtgatgccg ttccacaaca agcccggtgc gtggtagcgg gcgctggagc
    10201 gggagaagaa cagggagcca gccatggtgt gcccaatctc gcagagatag gcccgcatgg
    10261 ccggggtgtt cccccagctt gtggtcagga tgtcctggca acgcttgacg tacgaacgct
    10321 cgatttcggc cagcctggcc gcggtccagt cggcgaactc ttggacggtg aagccgtgtt
    10381 ggcgccgcag aatccaggag gcgctcatgc ggtcgtcgca ttcgacgaac cactccttgc
    10441 gcagggagat gaggtcgttg aagacaatca gatggtcgct ggcgtcctgc cacacgccga
    10501 acagttcggg gtgctcggtg aacatgtctg tgaagtcgag gccgagggcg tactcggcga
    10561 gtagccagca gtaggttccg tagacagtct cccgacgcag ctccatatag gcgtcgaggt
    10621 ccagctcggt ggcgtgttca cgtacggcga cctcggtaac gctgccgcgc aagatcctca
    10681 tgagataggt gatgaaccgt tcgcgcagtc catcgggcat gtctgtggtc aggtcgtgcc
    10741 aggtgtcatg ggccaggcgc caccaggctg gggcctcctg aggtacgggc tgggtgccgc
    10801 gcagcaggtc ttcccactgc tcgaccgcgg cggcggcata ggcggagcta ttgccgaagg
    10861 gagtgtcgcg cgtggtctcg tcatcgacga tcgtcagcac ggtgcacagg cgggacatgc
    10921 gcagaatgcg gtcctcgcgg gcgtgtggat aacacaggca cgtccacagc tcgtaaccgg
    10981 cgttgagcca ttcctcgaca tcggtgccgg cgacatcgcc gacgtaggag cgcacccaag
    11041 cgggtgtgtc gtactgagcc tgcggcagca tgggatgcat ccgcagcggc aggataagat
    11101 ccatctccgg caggcggtag gtgagttctt ccggccgcag ggcgacatcc gagtccatgc
    11161 cagtcctttc cgtggtgtcc ttgacgtggc cgccggtata gcggcgagtg gctgggatac
    11221 aacgtcctcc cagcggggca gcgacatgtt ccgcccttat cgcgccgcca agtccaacgg
    11281 cgccggagac agccaagtgg tcatactctg cacccaactg gggcccggtc gtggcgccga
    11341 tgaagttccg gaccgcccct ccggtcttga ccatggtgct ccctaccctt caccgaaggg
    11401 ctacgacgca cgatcaccag cccgcatccg atatcgatca ttccttgctg tcgcaggcca
    11461 acgcgatacg ggattcagcc aaggggtcaa cagctctcgc cgatcacgcg cagcggacag
    11521 ccgcgctgca cgcatgattt cgcggccagc gtcccggccc agctcaccga tgacgaacga
    11581 gccgccgtcg acgacggtca ggccgctctc gactcgctcc ttgaacggct caccggtgtc
    11641 cccacctctg ccgggccgat accacgacag atcggactgc ccgccacggc gacactgctg
    11701 ccggcttgcc gccagcgaag acgaagtcgc gcaggacttc ggtgacctca ccgggaaagc
    11761 cgtcgtcggc agcctctcac cctcgtctcc gtcgcgcacg ccttctgcac cctgcagcga
    11821 ctgactcgat ccccaaaaga gacggcgtcg gcccgagcct ctaccaagtc gcccccgagc
    11881 tgcagctact cctcgcggtc tggaccggtg cctgccccac ctgtcaccgc gacatgccca
    11941 cacccacacc aacctgacca agcactacta ctgatctttt cgttagttct gtgggtgtga
    12001 cgggcttgtt ggtgggacgc tgatgttgtg tcttccaagc cttcgcctgt tgcttccaga
    12061 tctgtcgttc ctcctttgac gcggccgcag ttggccgagg cccggcgcgt acgggcggcc
    12121 gagttgttcg ggcaaggacg cgcgagtgcc gagatcgcac ggatgctgga ggtcagtgct
    12181 gagagcgtgc ggcggtggaa aagggtatgg gaggagggcg gcgctgatgc cctgcgccgg
    12241 cgtccggcca ccggtcgtcc gcccaagctg gatgacgccc aggtcgagca ggtgcggacc
    12301 gcgctggagc aaggcgccca ggcacatggc ttcgaggctg atctttggac gttggagcgg
    12361 gttggcctgg tcgtcgagcg gatgacaggg gtctcgttgt cgcgggcgtc ggtgtggcgg
    12421 ttgctgacgg gccggctggg gtggagtctg caacgcccgg agcgtcgagc ggtggagcgg
    12481 gacgattccg agatcgcccg gtggatcacg cacgaatggc cgcgtatcaa aagggggcgg
    12541 tgaacaaacg tgcctggatc gtcttcctcg acgagtcagg agtctcactg ctgccccagg
    12601 tccgccgcac ctacgcaccc cgcggccata ccccgcttct gcggcatcgg ctgaactgga
    12661 agcgcgcctc gatggccgcg gctcttggct accacgccgc cgagcccgac cgcggacctc
    12721 gtctgtgctt ccacctcaag cccggcagct acgacaccat cgccctcatt gaggtcctgg
    12781 aacagctcaa ggtgttctac cgcggggaac aggtggtact gatctgggac ggcctgtccg
    12841 cccactggag ccgggcgatg cgggcctggg ccgccgagca ggactggctg accctggagc
    12901 gattacccgc atacgcgccc gagctcaacc cggtggaact gctgtggtcg tcgctcaaga
    12961 agcgcgaact cgccaacctc gccggcgacc accttgccga cgtcgccgat gccaccgagc
    13021 aaggcatcca ccgcatcaac cacaaccggc aactgccctg gtccttcctc acccacaccg
    13081 gcctgaccat ccacccacca accccacaga actaacgaaa agatcagtag tgccgcatca
    13141 ggcaacgttc gccctgttga cggtttgtcg taacggttgg gcgggggcga caccgctcct
    13201 acgtcggcgg ggtgggatgc tgatccgatg cctgtaaccc tccgccactt gggcgcccag
    13261 ttcttccctg cctggcttga gcgcagtcga gccgagtacg ccaaagatct tgtcgctgcg
    13321 gggcaaaccc ccgaggaggc tcaccggcgt gcggacgaaa gcatggcccg ctcttttccc
    13381 tccggtatgc cgagtccggg gcacgtggtc ttcgacgtgg tcgatgacgc cggggaaacc
    13441 gtcggctacc tctggatcgg accagacacg agcgacgacg ccggcgcctg gtggatctgg
    13501 gacatcgcga tcgacgccga caagcggggg cggggcttcg ggcgaatggc catggtcctc
    13561 ggtgaggaat acgcccgggc gcagggcgct catgcgcttg gtctgagtgt ctttgggttc
    13621 aacacgggtg ctcgcggcct ttacgagtcg cttggctacg agacgacctc ggtcaagatg
    13681 ctcaagcaac tcggctgagg ttcagacgac gttcgctcga cgagggcgca caggcggcgg
    13741 tcgtcggcgt ggcggtttcg ccagatgatg tagcggcgga tcgtgctgcc ctgttccggg
    13801 agtgtctgat cgacggcgga tccgatgatc aaggagacgc ctgatgagcg agaccatcgt
    13861 cgagaacgag gccatggagg aaccggtcgt cgagtcggcc gcggaggcgg tgtcggacga
    13921 gcagttgatc gcgatgctgg tcgaccgggc ccgtacggac gggctgcagc tgaccgggga
    13981 gggcggattg ctccagcagc tcacgaagcg ggtgctggag tccgccctgg agggcgagat
    14041 cacggaccac gtcggctacg gcaagcacga cgcggcgggc aggaacagcg gcaacagccg
    14101 caatggcacc cgggccaaga ccgtgctgac cgacgtcggc cccgtcgagg tcagggcgcc
    14161 ccgggacacg gccggcacgt tcgagccgca gatcgtcaag aagcgccagc ggcgcctgac
    14221 tggcgtggac gagatggtgc tctcgctgtc cgcgaagggc tgacgcatgg ggaaatatcg
    14281 gctcatctgg ccgaggtcta cggcgccgag gtgtccaagc agaccatctc caccatcacc
    14341 gacaaagtca tggaaggcat ggccgaatgg cagtcgcgtc cgctcgaccg cgtctacccg
    14401 gtggtcttcg cggacgccat caacgtgaag atccgcgacg gccaggtcgc caaccgccct
    14461 gtctatatcg ctatggctgt gaccgtcgag ggcacccgcg agatcctagg gatctgggcg
    14521 ggtgacggcg gcgagggcgc caagcactgg ctccaggtct tcaccgagct ccgcaaccgc
    14581 ggcgtcgagg acgtcctcat gctcgcctgc gacggcttga agggcctgcc cgacgcggtc
    14641 gaggccgtct ggccccgcac ggtagtccag acctgcatca ttcacctcat tcgcaacagc
    14701 attcgatacg tcgcccggaa ggactgggac aaggtcgcgc gtgacctccg ccccgtctac
    14761 acggcgccga gcgaggccgc cgccaccgaa cggttcctgg agttctccga gaagtggggc
    14821 accgagtatc cggccgtggt caagatgtgg tccgacgcct gggctgagat ggtgcccttc
    14881 ctgtcgttcg acgtcgagat ccgcaaggtg atctgctcga cgaacgcgat cgagagcgtg
    14941 aacgcccgca tccgcaaggc ggtgcgggcc cgcggccacc tcccgtcgga aaacgccgcg
    15001 ttgaagtgcg tctacatggc gctgatgagc ctggacccga ccggcgaagc ggaactcctt
    15061 gcagtgcttc ggcgggcgcc cgccctgggg ataggccagg gcgtactcct tgagcgtggg
    15121 cgtcggccgt cgcatgacgc ggtccgagcg catccgcccc agcacctcca cgagcaggcc
    15181 gtcgaggaga aaggccatgc gtggggcgtc gtagccggcg tcgaagacga ccaggatgtc
    15241 gtcatcgccc tcttcccact gcccctggcc gatcaaatcg gtgaccacgc ggcggacctg
    15301 ggccgcggtg acttcggcga catcgtcgtc ggggccgagc cggaccgcgt cgagcagctg
    15361 gcaccacgac gtccgccggg tctccagcgc ggcgacgaag gaatagggcc agccggggat
    15421 gaactggtca ctggatcgtc ccgagcgtcc gtagacatga cagaacaagc ggtccgggct
    15481 ggtcggcgcg tcgggacgca gccacgcgga gacatcgacc accaacacca gacgcccgtc
    15541 ggcggccttg ggctgcggca gcatggccag cgcgcggcgc agcccggccg tgtcgatgcg
    15601 gccctggttg agcgcgtcgt acaacgcacc gtgcccacgc cggtgctcgg ccagcagcct
    15661 caggtcgacc ggcgagatta ccggcccgtc ctcgcacagc atcgcgtcgc ccagctcgaa
    15721 caaggtgtca ccgcgccagg tcaggcatcc gtagaagtcc tcccgaaagt gggacgcgaa
    15781 gtcgaaagcg tcccgccggg catcgtggtc gagcacactc acctctgcgg ccttcgtatg
    15841 aacatgattc cgtggcggaa cgcatgctca tgcgagggcc gtccgactgc ccggcgaatc
    15901 cccggacgag tgaaaccatt cgaggcatcg ttcgaggtcg tggcaccatg tgcggtatga
    15961 cgacgactcg aaaggtccat gccgcgtaga cggccaggac atgtccgggc gggccttccc
    16021 cgccgacacc gggcccagaa caccagacac atcggcgact tgcccccgcg agtgctgtcc
    16081 gagatcgatc gcctggagcg cacccgcaac tacctttacc caggggacgt cagcaaggca
    16141 gtgcgtcttt gggaggactt cgttcaccgc cccgcgcgcg agctatggcg cgattacgac
    16201 gggctctggc acgacgacga ctcgctctac ctccactggt actgctgcgg caacccgctg
    16261 gaagcccggc tcctccttga cgctgcgatg cgagccatgt caccccgtgg agcccgcgag
    16321 ctccagaaga tcatcgacaa gctcgatgcc ttctggaccc cgccctcgcc atggccaacg
    16381 acggtcggag gttaaagaac aagctcagcg ccctggctcc aggtctcagt ggacggttcg
    16441 tgagtctttg agtcgttctg tggtcgcctg atggtgtgag gcgggggcgg aatccgcgga
    16501 ttcgtggtgc ggggtctgct ggggttggcg gggtgagtga acgcaagccg taccccagcg
    16561 acttatcgga cgagcagtgg tcgttgatcg agccggtgat caccgcgtgg aaggaccggc
    16621 accgctcggt cagcggtcat cagggcgctt acgacatgcg ggagatcgtg aacgcgatcc
    16681 tctatcaggg gcggaccggc tgtcagtggg cctaccttcc gcacgacctg ccgcagaaga
    16741 gtgcgacgta ctactacttc gccgcctggc gggacgacgg aaccgaccag gtcattcatg
    16801 aactcctgcg ctgccaggtc cgtgaacgcg cccgccgatt agaggacccg accctggtgg
    16861 tgctggacac ccagagtgtc cacgcggccg tcggggtccc cgccgccacg accggctacg
    16921 atccggccaa acgagtgccg ggccgcaaac gcggcgtggc agttgacgtc ctcggcctgg
    16981 tcatcgcggt cgccgtcctc gccgcgaacg tccacgacaa caccgcgggc atcgccctgc
    17041 tggaccaggt cgccgagcac accggcgaca ccgtccgcaa agccctggtc gaccagggct
    17101 tcaagaacca ggtcgtcgaa cacggcgccg gcctgggcat cgacgtcgag atcgtcgaac
    17161 gcgaccccgg ctaccgggga ttcctgccgc aaccgaagcg gtggagagtc gagcagacct
    17221 acggcatcct gatactgcac cgacgcctgg tccgtgacta cgagcaccgc atgtggacgt
    17281 tcgcgtaatt ccccgggggt gagttcacgc acttccccac ccccgcggct ctcggcgtct
    17341 acttgacagt ggtcttggcg ggcttgtcgg cggtgttctt ggggcgtttg ttcggtcggt
    17401 agctggggcc gttcatgatg acttgatgac tggtgttgat cagcctgtcc agcaacgact
    17461 cggcgacgac ggggttggga aagaggggat accagtcact gggagcccgg ttgctggtga
    17521 tgatcaggga ccggccctgc cgttcggaga cgagttcgta gaggtcgtcg gcctgggctg
    17581 cggtgagttg gcgcatggcg aagtcgtcga ggatgagcac atcgggacgg accagttcac
    17641 ggatgcgctt ctgccaggtg cggtccgcat gcccgccggc caggtccgcg aggatccggc
    17701 tggtcttggc gaagcggacg tgggcgccct gccggacggc gaggtggccc agggcctggg
    17761 cgatatgcgt cttgccgaca ccgaccgggc cgaacaggat gacggactct ccggcatgca
    17821 gccagcgcag ggctccgagg tcgcggatct gggcggcggg cagtttggag gaggccgtga
    17881 agtcgaactc ctccagggtg acctgctgct cgaacttcgc ccgcttcaga cgacgttgga
    17941 aggcgacggt ctcgcggcgg gtgatttcgt cttggcaaag gacttgcagg aagtccaggt
    18001 gcccgagttc gccgccgtgg gcctgggcca ggcgggcgtc gagggtctcc agcatgccgg
    18061 aaagccggag ggctttgagt gactcgcgca gggcggtgtc catgacggtc atcgggcttc
    18121 cacctcggct tcgtcgcggt cctggtcgcc gtggtgctga tctgtcggcc ccgggggggc
    18181 gcgacggagg cgaacaggcg cttgggtccg tgcaggaagg ccgcggctcc ggcatcgccg
    18241 ctggtctcgg gctcgggatc ggtctcggtg ccggcgatga gaatgccctt gatggtgcgg
    18301 taggtggggt cgccgaccgc gatggctctc gcgcaggcgg cttccagtct tcggtcgccg
    18361 tacttcttcc gcagtccgag aactccctgg gcggcccgga gccggtagag cgcgttgacc
    18421 tccagcagtt ggtcgacgac ctcgcggcag gcgtcgccga cctgggatgc ctggcttcgg
    18481 caccacaccg gagtgcgcat ctggaaggcg atcttctccg gcggatagtc gctcttgtcg
    18541 gtccgttttc cctgctcaag cgccgcatgg gtcttgacca gctgaccgtc gaggaagacc
    18601 tggaccaccg ttgcggtgga gcggacatcg accctgcggc cgatcagttt ccaaggcacc
    18661 gagtacaggg ttcggccgac cttgatgtga atgtccgggc cgaccgtggc ggtcgaccag
    18721 cgggccagca cgaacggggt cggcggcagc ggcagcagcg tgtctgcctc caccgtttcg
    18781 aacaccgcca tcggtgcggc accgctcaga ggccggcact gtcggcgacc ggcgacctgc
    18841 ttgctccagg tcacggcttc ggcctgcatg tgttcgaccg aggtgaactc ccggccccgc
    18901 cagaaggagt cgcggacgta gggcatcgga cgctcgactc tcggcttgtc cttgggcttt
    18961 gaggcgcggg ctggatcgac caatgcgccg tagtgggagg cgagttcggc atacgcctta
    19021 ttgatcttcg ggtcgtagag gtccggcttg tccaccccgg tcttcaagtt gtccggcacc
    19081 agccggcgcg ggaccccacc gaagtagtgg aaggccgcga catgcgcttc ggtccacgcg
    19141 tgctggtcca ggtgcaacac cggacggacg aacatgtgcc gcgagcacgg cagcaccatc
    19201 acgaacgccc agacccggtg ccgcttgcca gtgcgcgcgt tgatccactg gcccaggaag
    19261 ccgtagtcga tctgggcctc ctggcccggc tcgatctcgt cccgcaggac cgtgacctgc
    19321 gaccttgcca cctcatccgg caacgtggcg tgcacccacc ggcggaatga ggagatcgaa
    19381 accttcagct tgtgctcgtc gcgcaggcgc tggtggatcg tggagacggt gacggtcccc
    19441 agcaagtcct tgatgtagtc gcggtgttga tcgatctccg gccaggtcac ctgccgcagc
    19501 cgtttgtcgg ccagcctcgg aaaccactcc ttgatcagtt tggaccagtc agcctcgctc
    19561 atcggcggcc cacctggtgt gatcccggct gcctccgccg gcgccaagta cttccgaacc
    19621 gtcttgcggt ccacccccaa cgatgcagcc agctcgctct tcgagcggcc tgcgtaccag
    19681 tggacgtaga tctcggtgat gtcgaccacg acgaacgttc tcctcgccat ccaagctgac
    19741 catcagcctt ccgaaccgcg ggacgaggaa gacgaccagc tccacgatga ccaggtccct
    19801 cagtcccgag caccgccgta cccatggcca attaggtgga ttcgggatgg ggaattatat
    19861 gacgctcaaa ccgcccgaca tggggaaaaa cttgaccgtc gacaccgcac cgcctcgtcc
    19921 gcctcccgcg tctattgggc gatgtcccat gtcatgatcc gccgtctcac cggcacgaac
    19981 acctccacct ggcgcgagga ggcggtaagc gcgtgaacgt tcgccccctc cttgaggcac
    20041 tggacctgca agaggaagcc gcccgggccc tggctgacga ccttcgcgcg cagatcgacg
    20101 acctgcagac ccggctgcgg gaggccgaga cacacctcga gcacctcgcg atcacccgca
    20161 agaccgtcac cagcctcgcc gaccagctcc ccgcaccccc acccgaactg cccgagcacc
    20221 cggactaccc gcgcatcctc gccgccttca acgagtcgac cggccccctg cgagccaagg
    20281 acgtctgcca ggcccttggc catgaactgc tgccgaagaa cgtcgaaggc acccgggcca
    20341 aactgaagcg cctggtcaaa ctcggcatcc tcaccgaagc cgacaccggc tgctttaccc
    20401 ggcgacagta gccggcaccg cggccagcac acctgtccca agcctcactt cgaaacggac
    20461 atcaactcac gaaccgccca ctcaaaaggg gcacgtccca gaaagccacg cgatgtgaga
    20521 gtggaagcaa gcgcagtgcg gtgccgttgt ggtcgactga tcgcttgcac aggcccaagg
    20581 aggctccccg agcgagccca ggacacggct gagcccaggg ccacgacaga caggtcaatc
    20641 cctcgcgccc gcggcagacg tggcgctttc cgactccgac gcagccggac cggcaagagc
    20701 gcacaactcg tcaaacgccg cgctccacat ctcggggaga ctgtctgcgc ccttcaaagt
    20761 gcggtcggta gtgaagcaca cgaacgaggt cccggcgtag cgtgagatcg cgacagcgac
    20821 gcggtggccc gccggcagga agacgatggg gaggatctgc tgcacgctgc ggcccagcac
    20881 gcgcagcggg atgggaggcc cggccacggt ggttgcgagc agggtgttca cgttcgggcg
    20941 gaggttccgc tgcaagcccc aggagagaat ggggcctggc agtagctgca gcaggggcgg
    21001 cagaagcgca tgcgtggcca gccgtttggc cgtgcggctg cgctgggcga tttcgttgag
    21061 ccgagccaga acatcgggtt cgtcgatcgg cagggagatc cgagagctga cgatcctgtt
    21121 gccatgcgtg tcgcgctcgt tggtgcggcg gatgctgatg gggaccaggg ctgtgacctg
    21181 tccgtccggt cgcagcccgc aaccggcgta ccagtcacga agggctccgg tgagggctgc
    21241 gaggataacg tcgttgggtt gcgcgcccaa ggcatgcgca caggacacga gccttcggta
    21301 gtcggcctgt gcccagacgt acctcatccc gtcggcgccg gcgcgtgtgc cgggagtcag
    21361 cacactggca cgggggactc ccagcagagg tgcgaccagc gcacggactg tgcgcgccga
    21421 ggtgagcacg gtgaagcggc cgatccgagc cgggctcttg ggcatgggag ctgttcgcga
    21481 gggcaggcgg tcgcgatcac caaccggtac tgcgggagtg aagcctgtcc ccgggatgct
    21541 cgccagacgc gagagcagct ggatcccacc gactccatcg atcagcaggt gatcaaatcg
    21601 aatggccagg gcgaacctct gcggcgcgta gcccaccatc cagacgtccc agccttcatc
    21661 agggaggctg gctgagtagc actcacccaa tacctctccc agcttcgttt cgtccggcgc
    21721 ctctgccagc gtcacctgat gttcgaggat tccagccgaa cccggccgcg aagcggtggg
    21781 cacatgaccg gtcagggtcg acaccaggtc aagcagctca gcacgggtgg gatgttcacc
    21841 ctcgcacagg aacacaaaac cgatcgccgt ggaagcatcg ggattgcgcc gctgatagga
    21901 cttccaacct gcagtgaggt gatcgcccct cactgctggc tttccccagg ggaccttcat
    21961 cgaaatcacc tttcggagtg gcagaccgaa gtaccttcgg ggtcaacgag cctgcacggc
    22021 gtggggtatg ccctgaaggc gccacgtgtc ggcaattcgc ggttcgggct tgaaagcggc
    22081 actgtttggc ttggcgtcct ggggtgccgc ttcccggcct gcctaacccc aacgtctaca
    22141 ccgatggggc tcgcactgtg gccaagctgc ctggtcactg gagttcccag gtgtcgcggg
    22201 gcaattcgac caggtagttg atcatgtggc gcagggcggt ctcgctcgat tcgggggtgg
    22261 ggggctgtgg ggccggtggg gatgcgcccc agggaggtgg ggaaggcgtc gacgtcgttg
    22321 taggcggtca tcaggttggc ggcgcgctgg atgacgctgg gcgcggcgga ggttgagctg
    22381 cgggcgagga ctgcgttgat gactgtgtcg gcgactgcgg ggtcgatgag acgggtgcgg
    22441 aagaccgcct ggtcgatgtc gcggagttct tcgtcgttct gggcgcgggc ggcggaggcg
    22501 tcgtaggcga tgtcgatgat gcgttccatc ggcagggcgg ccgggcccgc ggtgatccag
    22561 tggtcgccgc gcgcgctgtg gtctcgggcg agtgcggcga gtgcggcggc ggcagtatcc
    22621 cgggggatga ggtcgacatg ggtgcctggg gtgcagggta ggaagggcat ctggccggaa
    22681 agggcgacgc cgagcaggta gtggaatgcc tggagacggg gaacttcccc cgagtgggag
    22741 tctccgatca cggtggagat ccgggcaatg cagctgggca ggccggactc gcgtaccagt
    22801 gtctcgccgg cggctttgga ggccgcatag gcgccgaagg gggtgtggtc gcccgcgcgg
    22861 gagatgaaag cggtggagcc gtgcacgagg tgggcgccgg cgtcctcggc gaaccgcagg
    22921 acgtggccgg ttccgacgac gttgacccgg tgcaggtgct cgggcgtgat cgagaagttc
    22981 acgctcgccg cgcagtgcac gacggcgtcg actctggccg cgaggtcgcg gtagtcggcc
    23041 gggtggaggc cgagccaggg ccgggtcacg tcgccgcgta cggacggcgt gccgaccggc
    23101 ttgtggtggg tgagcgcgat ggcttcgtcc agctcgcgca gcagcgcgga gccgacgatg
    23161 ccggaggctc cggttaccag gatcatgggg tcctcacggt ggcggagtcg tcgtcccagc
    23221 tgacgttgtc gaggccggtg acctctacgg ttcgcgggtg gacgccggtt gtccgggcga
    23281 tgtgttcctt cagggcgata tgcggaagcc agtccgtggc acgggtaccg tcgggcaggc
    23341 catagacggc gttggcggtt cccgtcagga cgtcgatccg ccccacgtcg ctccgtcgca
    23401 gcacaccgtc cgaacctgtc agcagcaggc gggagtcggg gtggccgtca cgcaggtagg
    23461 cgcggcgggc ggggccggag acctcggcca aggggccggc cgggatgagc atgttgacga
    23521 tctggaagga gaccagcacg ctttcgtccc ggcacagttg gacgtcgacc gcgacgagat
    23581 cgtccggcag cacaccggcg aacctggctt ccacctcgat ctcgccgcag tccggcaggg
    23641 gggcgaacac ggcgagccgg gtgagctggt gcgggaagga cattcggccg ggcccgatgg
    23701 ccggttccca ccgttgcagc tcgttgtgtg ggatgacgtg cagtgcggcg tccagcagtc
    23761 cttggtgcag tgcgccgcgc ggcactgagc cgcgcccggc gtcgagcatc ccgctcgatc
    23821 cggcggagcc cctccgcaac gccgtcaggt actggaagct cggaccgtga aagagctccg
    23881 cgccctcgta tgggtccggc acgtccacga gatcaggcag gggggcgaag cgttccggac
    23941 ggggcggcgg ctcgaatccg accgttgcgt cggctaccgg tgcgaacctg gagagcgcgc
    24001 cggcctcgtg ccataccgcg agccgcgccg tgtcccccgc gcaggtcatg cgaagccggg
    24061 tcgggccggt gaccggcagc caccgctgca cgcgcaggtc atgcagtacg cggactgggc
    24121 gcccggcgtg gtcactggcc gctcgggcga ggaggtcggc tgttgacatc agcggtacgg
    24181 ccggcaccgt ccaggtgggg cagtggtccg ccagccaggt gtccgagcgg gggtcgagca
    24241 cggtgtcgac ggtggagggt gagtccggtg tgccggggac cgcacgtacc ctcaggcgag
    24301 ggacgtggta ggccctgcgg ccgtccaccc agagccatgc ctcggcctcg gcgtgcccgc
    24361 cctggggccc caactcgacg tccagcacgt ccagctcgat ggtgacgagg gcgtcggtcg
    24421 gtacgacctg gccgcggtac gtccacgagg ccggcacgac cgattcgaac cggaacccgt
    24481 cgccgacgcc acactcgacc aggtagtagc acaggagctg gcacatcgcc tcgatgccga
    24541 gtgagccggg ctgtaccggg tcgttgaaga agtgcgcctt gaagtaccag gcatcggccc
    24601 gcacgtcgca ttcggcacgc agccgtccga gtccggcggg gccgccttcg ggccagtacc
    24661 cggtgatccg gtcgagcatc agcagcatcg ggccgggcag gcgggcggag tgcccgaaga
    24721 accgcgcggg ccgggaccgg aggtcggtga ccgggcggtc acagggcagg gccagtcggg
    24781 tgcggtccgc gtccgtcacc ggcaggccgg tctgggacgt caactgggcc gcgtgcgtca
    24841 gggcgaagac cgcggtgccc tccagtgcgg gaacgccgtc tgcctcgcag cggatccgga
    24901 acgtctccac caccgtgccg tcccagcggt ccagcccgac gaactccaca gcggtcttca
    24961 acgaccgtac gtccggcggc acttcgcggg tggtagtcag gtggccgtcg aggttgcgga
    25021 tccgcagctg cgcgtcggtc gtccgggctg ccaggtagcc ggcgagaagg ccacagggct
    25081 gaagtacggc ctccatcagc gcggcggctg ggagcgttcc gctctgctcg cggaaccaca
    25141 cctgctcggg cacgtcgtac tcggcgacca ggtggctgcc gggccggggg gctccaatgg
    25201 tggcggacac ctcggtcagc cgggtgatga acaggtacgg cggtcccggc agccggaagg
    25261 catcgtcact cgcgccgggg aagatctcgt tcaccggtcc ccacgcgctg gcgagcatcg
    25321 ccgcgtggtc gtaccggacc gagcccacgg tggcggcggc cggatcgtcg tggccgcgca
    25381 ggccggcgag cacgcggggc ggtcccggat tgccggtgcg ttggacggtg gctgggccga
    25441 ggagccgcca gtgcgtcagg ggcgtgtccg gtacgagatg gaccgcgagc ccttcggctc
    25501 gcatcaccac ccggttgtcg atcgtgcaga ccgcatccgc gtgcacggtc gtgtccgtca
    25561 tcgaccggat cgtgatgtgg tagcgggacg ttccgtccgg ggcgttggcg aggaaccgaa
    25621 cacgggcggg ctcgtccggc tgcggctcga accgccagcc gtcgcggtgg accgtgcagc
    25681 aggttgcggc gagttggaac gagagcgcct ggaagcagcc ttcgagcagc gcggcaggtg
    25741 tccgccattc cttcggaagg gtgcgtccgg tcgcgacgag ccccatcgag ggggcgaacg
    25801 cggtgatttc atgcagcagg agcgtgcggc gcgaaccgag accggggctg cggacatggg
    25861 cgcgcgtcag ctcccagtcg ttgccggtga aacagtcggc cgggcggccc tcggcgaatg
    25921 ccgtgacctc gccggggccg aatccagcgc ccgtgtgctc gggcggcagg ccgtggctca
    25981 ggccctccga ctcggtgccg cgcagcgaca gcaggccgtc gaccctgccc cggaaggagc
    26041 gcccgctgag ggtcagcgag ctcagtagcc gctcacccgg cgcggggagc ccttggtgga
    26101 aggcgagttc gcagtcgagc accccgtcgc gctgcggcag cagctccagc aggtcgtgca
    26161 ccagggctcc ggccgtcatc cggcctgccc tgtcgaggta ccagccgccg aggtcgacaa
    26221 cggtgtgagc agtgcgcgcg ggactgcctg ccggttcggg gcgtggcacg tgaaggtccg
    26281 cctgagcggc gaggaagcgc tcgtgaaggt cggtggccag ccgcagctgt tcggagatca
    26341 agcctgcggc atccgccggg gccggggccg gggccggccg atgggacgtc gggggccggg
    26401 gcatgatctc gacgccggcc acgtcatcca cgggccacct cccgcagccg cgccagcgcg
    26461 cggccggcgg tgatcagcac gcgcggatcg tccgccgtca tggtcagttc ctcggcgaag
    26521 gagcgtgccc cggcctggag cgggatcatg tcgacgccgc cgagccggaa cacctcggcc
    26581 agctcggggg tgaccatgcc tgcctcccat ggtccccaca gcagcgagcg gaccactgtc
    26641 ccggggcggg ttgcctgctc ggcggcgagc acgtggttga gggtttcgtt ggccatcgcg
    26701 tagtcgcact gccccccgtt cccggtcgcg gcgacgaccg acgagaacgc gcacagcagc
    26761 cgcagcgggt cctcgcgggt ggcggacagc agtgcccgca gaccgtcgac cttggtttgg
    26821 aacacggcgt cgaactgctc ctcggtcttg tcctccaccc gccggtcggc cagcactccg
    26881 gccgcatgca cgacgccggt gatcggcccc cactgtgtcc ggacgtccgt gagcgccgcc
    26941 cgtacggcgt cctcgtcccg gacgtcggcg tgcaggtagc gggcctggtc caatccgtcc
    27001 acctcgcggc tcgggccgcg gccgaggagg acgaagcgcg cgcggtggcg ggagtcgagc
    27061 gcgcgcagcg ccgctgccgt gactgccccg gtcccgcctg acacgacgat caccggggcc
    27121 tccccgagag cgtcagtggc ggacggcccc ggtacgtgat cggggagttc ggcgagggcc
    27181 agcgtccacc gagtcccgtc agcagcaagc ccgacgtcca ggtcggggcc tccggccagg
    27241 agttcgtcga cgacggcggc ggcgacctcg gccgccgtcc ggtccgcgcg ccggcagtcg
    27301 atggccttga ccgcggcgag cggccattcc cagcggaccg tacgggcgag cgcggccagg
    27361 ccgccgagcc agggtcgttg cgcgtcgcgg tggccgaacc cgccgccggt gtcctgcacg
    27421 gtgacgaaga caccgccctc ggcgcgcagc cgcggcccga tcacctgcgc tgcccggaac
    27481 gcgtcccgtt ggacggccag ggcgtcgtcg atggacgtga tgtcggcgag tccgccgagg
    27541 aacagcaggc cggcggccgc cgtcctggcg aggtcggccg tggtgccgac ctctgcgtgg
    27601 atgcctcgct cggtgagcag ccgtacggct tccttggcga ttccggtgcc atcgtcggtg
    27661 accagcaggg tcccaagccc ccgcatgggt gagcccggtg cgggcgtgcg ctgcaaggtc
    27721 aggacatgcc ggcggatcgc ctgcacagga acagcagtgg tgagcggagc gggtgcgtcc
    27781 aacagggcac gcagacggtc ggcgatctca ccgaccgtgc gcagcgtcag aagcggggcg
    27841 agctgagccc ggtccacggc ttccaactgc gggaacatcg ggcgcagcgc agcgaggacc
    27901 tgggtgcggg tgatcgagtc caggccgagg tcgacctcca gctccatgtg cggctccagg
    27961 atctccactg ggtagccggt cttctcggcc acggcggcca gcaccacggc ctccagatca
    28021 tcgaggctgc gtacctcgac gggtgccggg gacatggcca cggcgggtac cgaggcggcg
    28081 actggcgcgg gcggtgggac ggcgggccgg tggagcggtc cggctgcggc ggtcggcttg
    28141 acgatgtggt ccgcagtgcc ctccagcgcc gtcagcgcgt cgatcgactt ctcggccatg
    28201 ctcagatagg ccgcgtgggc gcgtgcgatc tcctgctggg cttccgcgac cgcgcgcaac
    28261 gtatcgccgc ccagggcagc ggagttggac agcaccggtg ccggtgccgc gggcgagtac
    28321 tccgcgttcg gcgggtagcg cctgccgtgg ttgcccccgc tgatcagcat gggcatcgcc
    28381 ggtcgtgcag gctcgggccg ggcgggaccg tgccacagcc cggcgaggtc gagcgggaca
    28441 ccaagcgcgc agaggtgtcc gagcgcgtcg agcagtccgg tcacgccgtt gcggcccggg
    28501 cggtcgaggg cgatcgcgtg gacggcggcg agggactgct tgatcaggcc ggtcaacgca
    28561 ccgcccgggc ccacctccag gaagatccgc accccgtcgg tgtgcatggc ccgcaccatg
    28621 tcggcgaagc ggaccgggga ggtgacatgg tcggcgatcg cccgccggat ctcggcaggc
    28681 tccacagggt gcacggctgc cgtggcgttc ccgtacacgt ccagcagcgg tgcgcgcacg
    28741 gtcgccccgg acaggaacgc ccgcagcggc tccgtcgccg acgcgaccag agggctgtgg
    28801 aaggcagccg aggtgtcgag cacccgcgcc gtcatgcccg ctgcggtggc gtgcctctgt
    28861 accagtgccc ccgcctcggc ggttgcggcc accacgacct ggtgcgaagc gttgtggttg
    28921 gcgatccacg cctcggcgag gtcgtggcgt gcgagcagct ccgacacctc gtcgacgccg
    28981 gtatccaacg cgatcatgac cccggaggcc ccgcgcatca gctcgccccg acgggcggcc
    29041 agccgcatca gcgtgtcctc gtcgtacgcg cgcaccgcgt gcagggccac cagctcgccg
    29101 aaactgtgcc cggccacgca gtccggccgc acccccaccg catccagcac ggccaacagc
    29161 gcgaggctgt gcgcggcgat ggccggctgc gcggcgccgg tgtcggtgag cgcgcgccgc
    29221 tgcgcctgcc gctcggcgtc ggtgaacacc ggtgcgggga agacgagccg ggacacctca
    29281 tgcctgttcc acaccgcgtg agcctgcgga aggtgcatcg ccaggtccgc acccatgccc
    29341 acgtactggg ccccctgccc cgggaagagg aacgcgatcc ggcccggcgc gcgcccgacg
    29401 ccgtagtgca cacccgaggg cgtcgagaac ggttctgtgc cgacccggcc gcgcgcctgt
    29461 tccagcttct gtgcgaggtc ctcagtggac gaggcgacca ctgccagccg gtgcgcctct
    29521 gtgctgcgga aggtctcctg gctgcgccgc gcgatggccg tcaggccgcc cgaaaggtcg
    29581 cgggagaaga gctcctgcgg ggtggcggcg gacagcacca ccagctcgca cggccgtacc
    29641 tcgcagcgca ccgagtggcg ggtcctgggc gccatgccgg cgtactcctc aagcgcgaca
    29701 tggaagttcg agccgccgaa gccgaagctg gacaccgagg ctcgccgagg gtggtcggcc
    29761 gtgtggatcc acggccgcgc ctgtgtgttg aggtagaagg ggctctccgc cagcttcagt
    29821 ccgggattcg gccgagtgac cttgatcgtc ggcggcagca cccggtgccg caacgccagg
    29881 gtggccttca gcagcccggc ggcgcccgcc gcggccttgg cgtgcccgat ctgggacttg
    29941 acggacccca gtgcgcacca ctggcggtca gcccgtccgc tcgcgtcgaa caccgaacgc
    30001 agggcggcga gttcggcggc gtcaccggcg gcggtgccgg tgccgtgcgc ctcgaccagc
    30061 ccgaccgtct ccggtccgta gcccgcagcc tcgtatgccc ggcgcagcgc ccgcgcttgc
    30121 ccggtgtcca gcggcgcata caccgaggtg ccgctgccgt ccgaggagga gccgatgccg
    30181 cggatcacgg cgtgcacctg gtcgccgtcg cgttctgcgt cggcgagccg cttcagggcg
    30241 aacagcgcga tgccctcgcc cagcatcgtg ccgtccgcgt gctcgtcgaa cgggcggcag
    30301 tcgccgctgg atgacagagc cggggtcttg ctgaagcact ggaacgtcaa cgggtcattg
    30361 agcgtgtcca ccccgccggt gatcaccagg tcggagcggc cgagcagcag gtcgtccgcc
    30421 gcgaccgaca gagcagccaa ggaactcgca cacgcggcgt ccacagtgaa gttggccccg
    30481 tgcaggtcga agcggttcgc gatccggccc gccaccacgt tgctcagcag gcccgggaac
    30541 gtcgcctcct gccatggcgt cgagtagtcc gcgatccggt cgcagaccgc atccgcgtcc
    30601 gcctcggaca gcccgctgtc cagcagagcc cggcgccaca acgggcgccc ggcccgcgcc
    30661 gccatctcac cgagtagctg caacgaggca cagccgagga acacgccgac ccgctcgccg
    30721 tcgacctggt cgagccctgt gcccgccaga ccggtcagca ggcgctccgc ggcgaccagt
    30781 gccagcaact gggcggtgtc ggtagcgggc aggtttcgcg gcggcacccc cagggccatc
    30841 gggtcgaact cgacctcggg aaggaatgcc ccgcggcggg cgtaagtctt gtccggagcc
    30901 tccgggtcag ggtcgtagaa gtcctcgatc agccagcgat cggccggcac gtcggtcatg
    30961 aggtcgcgcc cctcgatgac gttgcgccag aaggcgtcca catccggggc gcccggcgtg
    31021 atcgcgctaa cgccgacgat cgcgatccgg tggtccaagc tcatctgccg ttcctcaagc
    31081 cagtgggcga ggccggaagt cgaagacttc ggcgggaaga cggaccccga gggtgcgcag
    31141 ctggtgcgcc cgggtcagca ccgcggctcc ctggagcagg ttgcgggcga tctgtgtgac
    31201 cgaacgccga ccgggatcgg ccagaaaact gccggcgacc caggtgttga aggcccctgc
    31261 ggcggggccg caccacagct ggtagtcgaa gcgccggccc ggcgcgccgt cgaccgccca
    31321 cgcggcagcg ttgcccaggt accagcggaa ggtcagggcc atccggtgct tcgggtccgc
    31381 atgcgcccgg gtgacctcgg caggagcgcg ctgcgaccag tactcctcgg tcagcttcca
    31441 cacatcgtcc agggaggtgc cgaagacctc gcgctccaag gcttgccggg tctccttggg
    31501 gatcgattcc agcgacgggt gggcggtgta cagctggtgc agccgggccg ctcggccggc
    31561 gaacttggtt ccgcgtcgca ggacctggac cttggcgccg agttcgaaca tgtcggccgc
    31621 tggcgccatc gccacgtccg ccaccccggc ctgcgcgagc atggccttcg cttcgtcgct
    31681 gacggcggcc tcgaccgaca tctggttcac cgagcccgtc acgacgtacg ccgcaccgag
    31741 ggcgaatgcc gccgccaccg cggccggatc gccgagcccg cctgccgcac ccacccgcac
    31801 accggggttc ttgcggcggg ccagcgcaag gaccgccggc agcaccgcaa ccagcggccg
    31861 accgtcggtg tggccaccgc tgtccgcctc gaccgtgatg tcgtccacca ccggcgtccg
    31921 ggccgccaat cggccctcgt cctcggtgag ttcaccgtcc ctgaccagtc ggcgcaccag
    31981 ttccgccggg ggcggggaca ggaacagctc ggccgtctcg ggccgcgata ccttggcgaa
    32041 cagcgcggtt ctccgaaaga tccggcccgc tgcgtcggcc cgcagcccgg agcccgagca
    32101 gcgcaccacc gcgggcgtga tgtccatgaa cgccgacacc gagatcttcg gtaccccagc
    32161 ccgcagcagg cgcgccgcga cctcgttctc catggcccga tcatgcggct ggtggatgag
    32221 gttgacaccc cagttgcgcc gcccggccag gccggtccgc aaccgctcca ggtcccggtc
    32281 gagacgtgcc agaccgagcc cggccgcccc gaagaacgcc agcatctcct cccgggccat
    32341 cgcctcgacc atctcgacgc ccgcgatgcc gtacgccatc tcacccgcga cgtaagggaa
    32401 tcgcacctgg tgagtttcgg cgaaggaccg gccgcccagc cactccgggt acatggccgg
    32461 caccgtgccg acagcggctg gcctcggccg ttccgagagc cccagcgcac cgtcccgctc
    32521 gcgggccacc agatgcaccg gcctggccac ccgctgggct agttcgacca ggccgtcgcc
    32581 gtggaacacc cctggcgccg tgtcagacac ggccgagcgc caggttgccc ggcgcccggg
    32641 ggtccaagct cgtgatgaag tcggtgaccg ccatcagcac ctcggcgtag ccgagatggc
    32701 cgtccgcatc ggcgtccagc acctcccacg cgtgctcggc gtggttccgg tccacgcgca
    32761 ggacctccgt gccgagacga atcgcctcat ccctggtgac ccgcccgtca tggtcatcgt
    32821 ccgccatcgc aaacgccaga ttggtgacca caccgatgta ctgcagtgtc ttgtccggcg
    32881 tctccgcaac actgttggcc atcaccacga cgaactgctc cgcatccagc cgcttcgggt
    32941 ccggcaccca cgcgggcttg accaccagcg cgtgccagat ccggttcacc gtcgcgacca
    33001 tctgttgcgc ccgcggcgag tcctgggcgt gcccggtcag ccgcgccagc cggtgcgcga
    33061 actgcatcgt gtccccgggg gtcaccgcac cgtcgccgtc gtcgtccagg acctcgaaca
    33121 tccacagctg cttgcgccgc aggtatgggt cctgggccgc cgccagccgt tccgcggccg
    33181 caatggtgac cgcagcgtcc ggcctgggcg cggccacggc ctcacccgtc agcgccacag
    33241 cgggcacggc accggctgcc aaccccgcag cgccgcgcag caccgtcctg cgggtcgcat
    33301 tcgtctcttc gttgcccttc ggcgtctcag ctaccacgag cccctctgtt cgcgcaacgt
    33361 gatcgttact gcacgctcgt ttgtgatctc atgcccggga ggctaacagc gtcacccgac
    33421 ccgccatgac ctgaaatcac tcaaattggt tatctaaaaa ccaagttgac atacagcggt
    33481 gccgaacatg ctagaaagtg ggccgccttg ggcatcgccg cttccgcaac cgccaatggt
    33541 cggcgcgcta ttcgacgctc tcgacggctt gggagcaact gtccgccctc gcccccaagg
    33601 aggtttccgt gaagccgctc ctccgcctgt tcgcctcgcc actgctggac atcctggcgg
    33661 caccgaacgg cgttgaccgc tgcctggcag cggtcaatcc gctgtggtcg gtgtccgaaa
    33721 cccgggcccg ggtattgcac atccggcacc aggcccggga cacggtgacg ctgaccctgc
    33781 agcccaacgc gaaccggcgc ggcttctgcg caggccagca tgtccgcctc ggcgtcgagg
    33841 tgaacggtgt acgtcgccag acttggactc cctcgccacc gcactctacg tggagactga
    33901 cggcctgctg aaggactcac cgcatctcgc tccgtggcgg ccagccaccg ggatcgctcc
    33961 acgactcacc gacgccgagc tggtcacgct cgcgatgatg caggccatgc tcggcttcac
    34021 ctccgaggcg aagtggctcc gccacgcccg agctcacctg cggcatctct ttccctacct
    34081 gccgaaacag cccggctaca acaagcgcct acgcaaggtc gccgagctgc ttcgccgcat
    34141 cacccggcta ctggccaccg acaccagcgt ctggagcgac gtgtggatcg tcgactccac
    34201 cccggtcgaa tgcggacgct cccgcgagac cgtcaagcgt tccgacctgg ccggatgagc
    34261 cgagtacgga tactgctcca gccacagccg cttcttttgg ggccttcggc tgcacctggt
    34321 gtgcacgttt cagggcctgc cgatcgcttt cgccctgacc gcggccaagg ccgacgaacg
    34381 cgaaacgcta ctggacctgc ttgccgccga accggaactg gtggccgccc ggcccggtca
    34441 gacgctgatc agcgacaaga actacttcgg ccgcgacttc gagcaccagt tggccgaact
    34501 ggacgtccga ctgctgcggc cgacccgcaa aggcgagccg gagcgggccg gggccccgct
    34561 gttcaagccg ctgcggcagg tcaacgaatc ggtgaacgag agcttcaagg ggcagctcga
    34621 cctcgagcag caccgtggtc gcacaccagc cggcgtcacc gcccgcgtca tgcggcgcac
    34681 cctcgcactg accgccgcga tctggcacaa cgaccacacc ggacagccgg tcctgcgatc
    34741 actgaccgcc cttgaccact gcccccttgg aatcgatcat ctaggcggca gcgccgcggg
    34801 aggactgtcg cccggaggcg ggggtcccgg tgcggggtgc acccgccgaa cgccgggcct
    34861 gggcggagcg ggtgcggcgg ccgcgcgtgg agaagccgcc gcgcttgggg cgttcgacga
    34921 ccggggtggt gatggtgacg ggaattccgg agggggtccg ggcaccggtg atgcggctca
    34981 gcgcggcctc gccggagcgg accttggtgg actgcggagt gatgccggcg tcggccatca
    35041 ggcggtccat ctcgcggcgc tggtcgggca ggaccagggt gacgacgctg ccggactcgc
    35101 cggcccgggc ggtgcggccg ccacggtgca ggtagtcctt gtggtcgctg ggcgggtcga
    35161 cattgacgac gaggtcgaga ttgtcgacgt ggatgccgcg ggcggcgacg ttggtggcca
    35221 ccaggacggt gacctggccg gtcttgaact gggccagggt gcgggtgcgc tgcggctggg
    35281 acttgccacc gtgcaggccg gcggcgcgga caccgctctt cagcaggtgc ttggtgagtt
    35341 tgtccacggc gtgcttggtg tccaggaaca tgatcgaccg gccctctcgg gcggcgatct
    35401 ccgttgtggt ggcgtgcttg tcggcgccgt ggacgtgcag caggtggtgt tccatcgtgg
    35461 tgacggcgcc cgccgagggg tctacggagt ggaccaccgg gtcggtgaga tagcgccgga
    35521 ccaggaggtc gacattgcgg tccagggtgg ccgagaagag catccgctgc ccctcgggcc
    35581 ggacctggtc gagcagggcg gtgacctggg gcatgaagcc catgtcggcc atctggtccg
    35641 cctcgtccag cacggtgatg ccgacctcgt tcaagcggca gtcaccgcgc tcgatgaggt
    35701 ccttgaggcg tcccggcgtc gcgaccacgg cctcggcgcc gcctcgcagc gcgctgacct
    35761 gccggccgat cgacatcccc ccgacgacgg tggccaggcg caggttcagc gaccgggcgt
    35821 agggagtgag ggcatcggtg acctgctgag ccagctcccg ggtgggtacc aggatcaggg
    35881 ccaggggccg gccgggttcg gcgcgccggc cggcggtgcg ggccagcagg gccagaccga
    35941 aggcgagcgt cttgcccgat ccggtgcgcc cgcgacccag cacatcgcgt ccggccagcg
    36001 agttcggcag tgtggcggcc tggatcggga acgggaccga caccccttcg gcggccagcg
    36061 acgccagcag cgcgggcggc atgtccagtt ccgcgaaggt ctcggccggg ggcagcgcgg
    36121 gggtgtgcgt gacgggtggc gcgaactctc ccggccgtgc ggcggggcgg cgcctgttgc
    36181 caccggagcg cttcgacggc tgcgagcggc ggccgccgcg gccggagtcg gcgaagcggg
    36241 agcggaacgg gcggtctttc gagcgtgctg tgcggttcat gaagaacctt cctcgataca
    36301 gtacgtcgag gaattcccgg cggaaacgag ccgcacacaa agaaccgcca gaacgaaccg
    36361 atgaaaaaag atgaaacgaa acgggtcgga aatatgccgg cccagcgggt cgccaaaggg
    36421 ggcggcggtc gaacaggccg ccccgcgccg cttgcgcggc cgttgcggcg cacaacggaa
    36481 aacgtccaag caacgagctg gggcccgcac ccaaggtgcg ggccccagcc acgggcgtac
    36541 gcgtcggcgt cagtgatcag gcgggaacga tgttctcggc ctgcgggccc ttctggccct
    36601 gcgtgacgtc gaaggacacc ttctggcctt cctgcagctc gcggaagccc tgggtggcga
    36661 tgttcgagta gtgggcgaag acgtcagcac cgccaccgtc ctgctcgatg aagccgaaac
    36721 ccttttccgc gttgaaccac ttcacggtgc cagtagccat gccatatctc cttcggggca
    36781 gtgcccggaa cccacaccat gtgagctcca gcgtcgccgc gatgatcacc ccgccggaaa
    36841 taccgccgga aaatacatag gtgcccccac cgtgtacgac ggcgagcgca cctgaagttt
    36901 tcgggaacca caactgcaac tgaaatagac gttagcacga ccctggcgac catgcacagg
    36961 gcacgagacg gggcatacgc ccgacgcttc cgagagcgca aaactcctac cccgccggtg
    37021 atcatttctg tagttgcggc attagatatt cgacaccggc gctcgcctct attcgaccgg
    37081 aaaaccgcgc cccctcggcc accgctcgag ctccgcaggc acgggcagac acgggcagac
    37141 acgggcgccc gcaccgacta cacctggccg taccacgcgg ccgtcggggg cagttcgcgg
    37201 tgcggcgcgc caggagcgac ggcgcacccg gggagccgaa gcggtaggcc gtttctgatg
    37261 gctcttgctg gggtggtgga tcagtgctct ggctgggcag ttgcgtcgta tggtgcggcg
    37321 acatgagctc acggacgagc agtggcagaa aatcgaggct ttactgcccg ccaatggcaa
    37381 gcctggcggg cagtgggccg atcaccgcac agtgatcaac ggcgtgctgt tcagagcccg
    37441 taccggtgtt ccctggccgg acctgcccga acggtacggc ccctggcaga ccgtctacga
    37501 acgccaccgc cgctggtcag ctgacggaac ctggcagcaa atcctgaccg agttacagat
    37561 cgaggcagac gccaccgacc ccgacgggac cctggccaag gacgtcgcga aggacggcgt
    37621 gccgcgtcgt cgggagtggg cggtgaacat cgactccacg tcctgccggg cccaccagca
    37681 cgcggccggt gcccgtcgtc ggccaccgcg ggactttccg caaaaggggg cggtgcgcgt
    37741 gtggactcag aggggcgtga ggcgctgggg cgctcacgag gcggactgac ctgcaaggtc
    37801 catctgctgg ctgatgatcg ggcccgcccc ttgacctggc agacctctcc gggccagcga
    37861 ggcgacagcc ccatgttcat ccctgtgctg gagggactgc ggatccgacg gcgtgggccg
    37921 ggtcggcccc gcagccgccc ggatcgtgtc cgcggtgaca aggcgtactc cagctacgac
    37981 aaccgtgctt acctgcgacg gcggggcatc aaggcgacca tcgcgcagcc cgaggatcag
    38041 cgggccaacc gccagcgcaa gggccaggcc ggcggacgtc ctccagcctt cgacaagacg
    38101 cagtaccgcc gccgcagtgc cgtcgagcgc tgcgtcagca agtggaagca gcaccgcgca
    38161 gtggccagca ggtacgacaa acgcgactac atcttcaacg gcaccctcac cgtcgcagca
    38221 atcgtcatct ggctccgcga caccgtccaa gagccatcag aaacgaccta gccctgttgc
    38281 tgcggccgag agaaatctcc attgaccgca gtagacattc tcacttcgga aagttagcat
    38341 ttctctcgta gtcaatgagg ccaatgaggc gcggcagaca cgaagcgccg cgagcacgac
    38401 agcaatacca gatggtgtgg aaaacccccg gggtctcggt gccgtatggc atcagggctc
    38461 ctcgacgcgt cctacgacga ggttcaatga cccgagagac tccctcacgc gccaccgaca
    38521 gattcgatga cgacgactac cccgcctaca ccatgggccg cgccgcggag atgatcggca
    38581 gcacgcccgc tttcctgcgg gcggtcggcg aagcccgcct catcgtcccc ttgcgctccg
    38641 aaggcggcca tcgccgctac tcccgctacc agctgcgcat cgccgcccgc gcgcgcgaac
    38701 tcgtcgacca gggcaccccg atcgaagccg cctgccgcat cgtcatcctt gaggaccagc
    38761 tcgaagaggc ccggcgactc aacgaggaac tgcgccggac cgctgccgac ccgagtcagc
    38821 ccaccggtcc ctgacgcgca ccgtcccgcc gcgtaacgtc ccccgcccac tgctgcgctt
    38881 cgaccgccgc acccgcatcg tcaccgctgc cctccctacg ccgtcgagaa cggcgagccg
    38941 gagcacgaca agaccgcgtc gagcaccacg caccagggcc atccccgaac gcagaaaccc
    39001 ccgccggagc cagccgacgg gggttccgca tctctcacct gctatcacac gcctaccacc
    39061 aacagcgtcg acgcacctgg atcgcaagga cttgacctgc gaaaacgctc ctgagctaga
    39121 ccacctggac ggcacaagac gcttccgaca acgtgtgcca agtggttcca ccatcgacaa
    39181 cgacgtggcg cagagacgcc tggaggcaac gtccgctggc cggcctgcct gcccacgtcc
    39241 tacggctcac actccggttg ggcatgagcc gtgcgcaggt ggcgctgccc gtgatggacc
    39301 actctgaggg ccttcctgac atccgatggt agagaccaag atccggacca ggcacggacc
    39361 aacgcgccgc cgacggcgcc ccgtgcatcg tttcagcaga tcagcactac gccgacgctg
    39421 taccaccaag cagaccaaga acctgctgcg cgccacgaca ctctcaggga agctgcttga
    39481 ccggattaca tatcagcctg tccagcggcg tagcacgtct gacgtcccat caaaacgatc
    39541 acaatttcgg cgtcgctatc gtccgtaaca ctcaaaccac acgtaatacg cacgcaaaat
    39601 cgaagttcag gagccctctg tggctaagcg gtcttggtga agtgtggtgc tgtttgggta
    39661 tgtgccatac caggaggggg gtttggaatg gcaggaccgt tgtgggtgga gctctcgtcg
    39721 gaggatgagg cggagttggg gcggcggttg agggctcggg acttgccggt gaatgagcgg
    39781 gtgcggttgg aatgcgtgcg gctgtcggcc cagggccgca acgctcccga gatcgcgtcc
    39841 attgtcgacc ggcatgtggt caccgtgcgc aaagctctgc gccggttcct tgacggaagt
    39901 ttcgaggccc tggccgacgc gccccggtcg ggccggccgc cacggtggac gcgcgaggac
    39961 ctggacgcgc tggaggcgat gctggatacc gcggcggctg aggggaccac gtggacgctg
    40021 cccgctttgg cggagtggct gcgccgagag cgtggggtaa atgtcgattc ttcctggctg
    40081 tcggtgctgc tgcaccggga cggtttccgc tggaaacgta cccgcgacag tctgcggcac
    40141 aaggccggcc cggccctcca ggccgccgcg tgggagcggc tggagggcct acggctgtac
    40201 ggctgagggc cgaagccggt accgaggatc tgtactacct ggacgagtcc gggttctctc
    40261 cgaccctgcc caccggtttc acctgggccc gcaccggtgt ccgcgctgtc gtcaagcggg
    40321 aggacaccaa gaaccggcgg gtcaacgtcc tgggagcact gagcgagagc gggccaggcc
    40381 ccgaactggt gtggagggcc gtcgaccaca aaattgacgc ttcgatggtt ctcgacttcg
    40441 tctgcacgca catcgcacgc ctgcccaaag gaacggacag tctcactgac ccgccgcctg
    40501 gttggcggcg ggtcagaccg tgcacgatcg tcatggacaa cgcccagatc caccacgcca
    40561 gactcttcaa gggacggcgt gaagaactgg aggccatcgg cgtccacctg ttctacctcc
    40621 caccgcgatc gccggagctg aacctcatcg agcgcatatg gcgctcagtg aagtaccagg
    40681 acatgcccgt ccgtgcctac accagcacca ccgcactaca caccgccgtc gaccaggcaa
    40741 tgacccgacg ggcaacagca ctgacaccaa ccacagaaga cttgctcaag accgcttagc
    40801 tcaagggccg cgacgcacgc cacgtgatgc gtcattggga acacgtgggg caatcagcga
    40861 accgcccgcc cactctgcgc ttcaccgcct atctcggcgt tctgggccgt agggactcca
    40921 cccattcatg tgtgccttga gctcgtctgg cgtcggttcc cttggagttg gcatctccgg
    40981 acgccggttc aagggactga tcgcacaaac gaattcacgt gcccactcca accaacgtct
    41041 tgccgattcc agtgccggct cgtccacgac gctgcccggt tcggcaagac gacgttccag
    41101 agcatcgcag tactcaccga gtactgcagc ctcctgccag cgcccggcct cctcgcgaag
    41161 cacctctgcg agttgatcca tctgctccct ggggaccacc gacttgccgt cgaggtggcc
    41221 gcagcgcttg ggggcgacct ggtcttccag gtgcagcccg gccagcccgg cgtcctccat
    41281 cagctggacg gtgcgggcgg cgttcagcgg ttcgccgaag ccggtgtcgg cgtcgatgag
    41341 gacgggcagg tcggtggccc tggtcgtctg ctgggcgcgg gcggcgatct cggtggaggt
    41401 ggtcaggccg atgtcgggca gtcccaggtc ggcggcgagc acggcgccgg agaggtaggc
    41461 ggcctcgaag ccggtgtcct ggatgaggcg ggcggagagc gggttgaggg cgcccggcat
    41521 gggcagcagg cgtccggtgg ccagcctcgc gcgcagggcg cggcggcgct cggcggggat
    41581 ggtgcgggtg tgcagcatca gaacaggccc ttcggcaggt gggcgtcgtg cgcggtgacg
    41641 gccgcgatgt cgacggccgg gaacagcgcg tcgagaccgt cggcgtccag gtcggcgagc
    41701 cgttccgccg tgtcgaggaa gcgcgttcgg gcgtcggggg cgaggatccc ctcggtcagg
    41761 gtgcggaact tggccgcgta gtcgggccgg cggaaggggc gggccccggc cggatgggcg
    41821 tcggcgacgg ccagttcgtc ctcgacgacg gtggcgtcgg cgagggtgac cacggcccgg
    41881 ccgccgaagg cgcggggggc cggatcgggc tcgtggtagc ggcgggtcca ctccgggtcc
    41941 tcgaccgtgg tgatccgccg ccagagttcg accgtctccg gtcggcgggc gcggtccggg
    42001 gcgtaggagc gctcgtggtg ccaggtgccg tcctccagcc cgcaggcggt ggcggcgccg
    42061 aggtgggcca cgtggtcgat gcggtgcgcg tgcaggcaga tgcccttgac cagggcgacg
    42121 tggatctcgt aggcggcgac gatcccacgg agcaggtcgg cgccggtgcg gccggtgtgc
    42181 tgggcgacgg cgagcagggg cgggacgttg tcgccggggt gggagtagtc ggcggccagg
    42241 tacgtgtcgt ggaagtccaa ctcgcgcacg gcggtgccgt tggcccaggc ggcccactcc
    42301 ggggagaccc gggcgacggt gccgagggcc gaggcgccgc gggcggtcgt cgggtgggcc
    42361 agggcctggg cgcgggcgac ggcgacggcg accgggcggc gcagcagggc ggcgacggcg
    42421 accgcggcgt tgtcgatgac ccggttgacg gccatggcgg cgctgtcgga ggccggctcc
    42481 tcggtgccgg tggcggcctg cacgagcttc caggcgagtt ggtcctcgcg gggcagtcgg
    42541 tcggcgctgg gggtggacgc ggacgtggtg ttcgagcgcg ggactccccg ggggatgtcg
    42601 ggcggtcctg tcgggtgccg gtgcgatcga gcctgcccgc gcgacggccg tcgggccacc
    42661 gctccgacgt gcggaatccg taccgccgtg ggctgcgaat ctgcgaaacc tgcgaatgat
    42721 gcggatgcta cttttgccga cacgcgaacg gcccggacac ggaggtgcgc gatggcccgg
    42781 cgagcggccg gccggaaggt ctacgcccgt gccaggctgc gccgactgcg ccgcgagcac
    42841 gggatgaacc aggtcgacaa ggcccgtgcg ctcggcatct ccaccagtta cgccaaccag
    42901 atcgagcaga gccagcgccc gctgaccgcc ccggtgctgc tgcgcatcgc ggaggtcttc
    42961 ggcgtcgacg cggagttctt ctcggaggcc gcggaggacc ggctcggcgc cgagctgagg
    43021 gcggccctgg ccgacgaggc ttgcggggtg ccgatgcccg ccttcgagga catcaccgag
    43081 gccgcccgcg accaccccga ggtggcacgc gccctggtcg ccctgcacca ccgctaccgc
    43141 gacgcggccg agcaggccgc cgccctcgcc gcaccgggca ccgacgcccg ccgcgcgccc
    43201 gcggagccgc acgacgaggt acgggacttc ttctacgccc accacaaccg cttcggcccg
    43261 gtggacgacg cggccgaaca caccgccggg gccctggggt tgcggcccgg ccgggccgtc
    43321 gacccgctca ccgcgcgcct cgccgagcgg caccagatca cggtcgtgca ggccgccgcg
    43381 ggccactccc ccgacgcccg ccgcttcgat ccgaccaccg gggtgccgtt cctgtcccgc
    43441 tggctcagcg acggccagcg tgccttccaa ctcgccaccc agttggccct gttggagcac
    43501 gggtcgctgc tcgacgggct cgccggcggc gccctggagc tcacctcgcc ggagtcgacg
    43561 gcactggccc gcagcgggct ggcgaaccac ttcgcgggcg cgctgctcat gccgtgctcc
    43621 gccttccacg gcgtcgccga ggaggtccgc tacgacatcg agctgctgtc cgcgcgcttc
    43681 ggcgtcggct tcgagacggt ctgccaccgc ctgagcaccc tccaacgcac cggccaccac
    43741 gccccgcgcg ccgagttcgc cgtcgcgctg ggctgcgagc tgcggcacgc gcaccgcctc
    43801 gtctacgccg agggggtcgc cctcgacgac ccgcgggccg ccacgcccat cggcctgggc
    43861 tgtcggatct gtgagcgccg cgactgcccg cagcgcgccc ggcccccggc ccggccggct
    43921 cgccatcgac cccgaccggc gcacctacgt gccgtatccc gtggaaggac gcagtgccat
    43981 gcccgaagca ggaggagcca ccgcgtgacc agccgtatca ccctcatctc accggcgatc
    44041 ggcccgtcgc tgcggcaggg ccgcttcgac gacggcggcc cgctcgacgc tgttggagcg
    44101 gcacaggcca gggcggcggc cggtgccctg ccggccgccg gccgggtctg tgtctccccc
    44161 agcgtgcgct gtcgggagac ggccgcggcg ctcggcctcg acggcggccc gtcgggtccg
    44221 gagctcgcgg gtctggacgt cggccgctgg tcggggcgga ccctcgacga cgtggcggcg
    44281 gccgagcccg aggcggtggc ccggtggctg accgatcccg gcgcggcgcc gcacggcggc
    44341 gagtcggtgc gggacctgtg cgggcgcgtc gcacggtggc tggacgcctg cggccgggcc
    44401 gacggcagga cgctcgccgt ggtcgaaccg gaggtcgtac gggcggtggt ggtgcatgtg
    44461 ctgggcgcgc ccgaggaggc gttctggcgg atcgacgtgc ccccgctcac ggccaccgag
    44521 gtcagcggtc ggtccgggcg ctggaacctg cggctcgggc gcgccctcgt cgccgacgcg
    44581 gagcccgaca gctgacggct gcagcgggtg cgccgcgtgg ggtcagtggg cctcgtcccg
    44641 gtggcggcgg agcagctccg cgatcgcgcg gcgcaggcgg tcggtgtcgg tgcggtcgtc
    44701 ggggccgccg accagggcct ccagctccga gagcagtcgc tcggtccgtt tgacctgctg
    44761 ggcgagcacc cgtacccgcg cgctctggcc gccgatctgg cggcggctgg cgatcagttg
    44821 ctcgtactcc tccggggtca gcgcgaccgc ggcacggccg ccgagggtga tgtgacgcgg
    44881 ctggggggtt ctggccatac ggctcctccg ctcgtcgcct ccggcggccc cgacccgtgc
    44941 cccgatcggg cggcccggac cggaccgccc gtggtgtgac cgtgacctcc gtcgtcgtgt
    45001 ccggcataac gcaaaagggc cctcggaggg ttccgaaggg cccttttgtg tcccaaaacc
    45061 gttcagttcg aggcgggaac cgtgtgtccg gacgaggctc tcgccggtgc gggatggagc
    45121 tgccgctcgg ccaactcacc gaagagcagc ccgaatccgc cccacagcac ggcctggacg
    45181 gccagtgccg agagccggaa ccgccacagc agggcggccg ggaagtcctt cggcacctcg
    45241 ttgacgaccg gcaggaactg gtacgccagc ccgatcacga cgacgaaggc ggccaccgcg
    45301 accacggtcg cccaccaggt gcccaggccg ggcacgaggc gcttgcccag ctgggtggcg
    45361 gcgaccgcca ggaggacgct gagcaccatc atcaggaagt acagcgtggt gcgcttgccg
    45421 atggtgtcgg gggcgcccac cgacggcggg ttggccgggt acttcaggaa cggcacgacg
    45481 tacacggcca gcagtgcggt gccggacagc agcagtgcgg tggcccgggg gccgaagcgt
    45541 ccgacgcggc cgagtgcgaa gcagaaggcg agggcggcga tgccgccgaa ggccactccg
    45601 tagaccagga cgccggtggc gagaccggcg gtggactgca gagtgcggga gacgacctcc
    45661 atctcgtgct cgtgggagtg ggcctcctcg aaaccgatcg cgctgttgac gctcggctca
    45721 ccgaggacgt aggcgacgac gagggccagc acgccggcgc ccaggccggc gagcatgccc
    45781 cgtacgagca gatttcttac cgttgcggag ttcatggggc tacggcgtcc cttgcgtcag
    45841 tggcagggga agccgagcag gtggcgggcg tcgtggaccc actcgtggac gtcggtgccg
    45901 ctgaacacgg acgtggcgcc ctgctccgcg cccacgaagt agagcaggac gagcatcagg
    45961 acgccgaaga agaccgccca cggagcgatc gccttgagcg gcagcgtggc gggaacgacg
    46021 ggagtggtgg atgtcggctg ggcgacggtc tgcgccatgg cagaacctcc ttctgggagt
    46081 tcgcgtccca tttcggtggt gcacaggacg acggccgcgg gtctgactca cgtcacaccc
    46141 ccgggggggg cgtgtcgcac acagtggcgc gaccgtgccg gatttccacc ggcttccgct
    46201 tcgccgtcgt cgctatcgaa gagaaggtac cgcgtgtcag gtacatcgcc aaggccgggc
    46261 caacgctcct gcgctgcgcc ccgacggggg gcccggccgg tggcggaacg ggtcagcggt
    46321 gggtgaagcg gggcgggcgc ttgtcgacga aggcggtcat gccctccttc tggtcggcga
    46381 gggcgaaggc cgcgtggaag atccggcgtt cgaagtggac gccctcggcg agggtggtct
    46441 cgaaggaccg gttgaccgct tccttgacca tcatcgcgac gggccgggac atgcccgcga
    46501 tggtcccggc gaccgccagc gcctcggccc gcagctcgtc ggcgggcacc acacgggaga
    46561 ccaggccggc ccgttccgct tcgacggcgt ccatggtgcg gccggtcagg cacatctcca
    46621 tggccttggc cttgccgacc gcgcgggtca gccgttggga gccgccgatg ccggggagga
    46681 cgccgagctt gatctcgggc tggccgaaga cggcggtgtc ggcggcgagc aggacgtcgc
    46741 agagcatcgc cagttcgcaa ccgccgccca gggcgtatcc ggagaccgcg gcgacggtcg
    46801 gcgtgcggag ccggccgagc cggtcccagg cggcgaacca gtcgctcagg tacatctccg
    46861 gatagtcctg tggctgcatc tccttgatgt cggcgcccgc cgcgaaagcc ctggccgacc
    46921 cggtcaggac gatgcagccg cactccgggt cgcggtcgag ggcttcggtg gccgcgacca
    46981 cctcgttcat cagccggagg ttgagggcgt tcagggcctt gggacggttg agggtgagca
    47041 gcgcggtgcg gccggtgcgc tcgaccagga tcgtctcgta gccgtccgtc gtcggtgtgg
    47101 tcatgcctgg cctccgcttc gctgcctgat gtcccggacg atgccggaga agtccgcctc
    47161 ggcgcccgcg ccctgggcgt attcctggta caactcggcg gcacgtaggc cgagttcggt
    47221 gcgcacccca ccggacctgg ccgcgtcggc ggccagccgg aggtccttgg ccatgagggg
    47281 tgcggcgaag cctggccggt agtcgtggtt ggccgggctg gtcggcacgg ggccggggac
    47341 cgggcagttg gtggtgagcg cccagcactg gccggaggag gtggcggcca cgtcgtagag
    47401 ggcctggggg gtgaggccga ggctctcccc gagcacgaac gcctcgctga ccgcgatcat
    47461 cgagatcccg aggatcatgt tgttgcagat cttcgcggcc tgaccggcgc cgggtccgcc
    47521 gcagtggacg ctcttgcgcc ccatggcggc gagcagcggt tcggcctcgg cgaactcgtc
    47581 cgggccgccg cccgccatga aggtgagggt gccggcctcg gcgccgacca cgccgccgga
    47641 gaccggcgcg tcgagcatcc gcatcccggc cgccgcagcc cggtcgtggg cggtgcgggc
    47701 gtcggcgacg gcgacggtgg agcagtcgac gaagagcgtt ccaggccggg cggccgcgag
    47761 gacgtcctgg tagaggtcca ggacgtggcg gccggcgggc agcatggtga acaccgcgtc
    47821 ggcttccgcg atcgcccggg ccgccgatcc ggcgggctcc actccggcgg tcgcggccgc
    47881 cgccagctgc tcgggggccg tgtcgtggcc gcgcactcgg tggccggccc ggaccaggtt
    47941 ggcggccatc gggccgccca tgtgccccag tccgatgaag gcgagggtcg tggtcaccag
    48001 gggacctcct gtgtcgtgcc ggacggggca agtcccagct cctccgcgcc caagggggcg
    48061 aagaagcggg cgacatgggt gtcgccgacc tccgcgaggg tgggcgggga ccagtggggg
    48121 ttgcggtcct tgtcgacgat ctgggcgcgg atgccctcga cgaggtcggg tgcggccagg
    48181 gcggcgcggg agacgcggta ttcctggtcg agcacggctt ccagggagcc gaggtgcctg
    48241 gcccggcgca gcgcggtcag ggtgaccttc agtgcggtgg gcgacttggc gagcagcgtc
    48301 ccggccgcct ccttggccgc cggatcgccg tggtcggaca gccgcccgac gatctcctcg
    48361 acggtgtcgg cggcgtagca ggcgtcgatc cacggccgct ggtcggcgag tcggccgggc
    48421 ggggcctgcc gcaccacgtg ccggtggagc acctcgcgca gcggtggtgc ggcgaggtcg
    48481 tccagcagtg cggggagtgc ggcggagggc acgtagtggt ccgcgagtcc gcacaggagg
    48541 gcatcggacg caccgatctg agtacccgtc agggcgaggt gggtgcccag ttcgccgggg
    48601 gcgagggaga gcagataggt gcctccgacg tccgggacga agccgatgcc ggtctcgggc
    48661 atggcgatcc gggaccgctc ggtgacgatc cgcacggcgg cgtgcgcgga gatgccgacg
    48721 ccgccgccca tcacgatgcc gtccatgagg gccacatacg gcttggggta gcgggcgatg
    48781 cgggcgttga gccggtactc gtcccgccag aaggcggccg aggccgagcc gtcgccgtcc
    48841 cgggcgtcgt cgtggatggc gcggatgtcg ccgccggcgc acaggccccg ctcgccggcg
    48901 ccggtgagca cgacggtctc cacggccggg tcgtgttccc agtccgtcag tgcctggtcc
    48961 agggcgcgca ccatggggtg ggtgagcgcg ttgagcgccc gggggcggtt gagggtcaga
    49021 cgggcggtcc ggccccggac ctcccgcacg acgggccgtt ggtccgtgcc ggtcaccgga
    49081 gggcctccgt cagtccccgg gccacgatga cgcgcatgat ctcgttggtt ccttccagta
    49141 tctggtggac gcgcaggtcg cgcacgatct tctcgatgcc gtagtcgctc agatagccgt
    49201 agccgccgtg cagttgcagg gcccggtcgg cgacggcgta tccggtgtcg gtggcgaagc
    49261 gcttggccat cgcgcagagt tgcggcgcct gcgggtcgcc ccggtcgagt gcctgggcgg
    49321 cctggtgcac cagcgcccgg gcggcggcca gttcggtcgc catgtccgcg agccggaacc
    49381 gcagggccgg cgcgtccagc agccgtccgc cgaacgcctc ccggtccgcg aggtggacca
    49441 ggctgctgtc gagtgcgctg cgcgcgccgc cgagggagca ggcggcgatg cccagccgcc
    49501 cgccgttgag ggcgttcatg gcgatccgga agccctgtcc ctcgtggccg agcagccggt
    49561 cggcggggag ccggaccccg tccaggatca cctggcgggt gggctgggcg ttccaaccca
    49621 tcttccgttc gttcgcgccg aaggagagcc cggcgtcgtc cttgtcgaca aggaaggcgg
    49681 agaccccgcg cggcccgtcg tcgccggtcc gcgccatgac gacgtacaac tgggcggcgc
    49741 ccgcaccgga gatgaactgc ttgacgccgg tcagcagata gtcgtcgccg tcgcggacgg
    49801 cgcgggtgcg cagggccgcg gcgtccgagc cggcgcccgg ttcggtcagg cagtagctgc
    49861 cgaggtcctc catggcgcac agcctgggca gccaccgctc gtgttgggcg gcgtcgccgt
    49921 agtggtcgac catccaggcg accatgttgt ggatcgagag gtatccggcg atggacgggc
    49981 agccggaggc gagggtctcg aagaccagga cgccgtcggc gcggccgagc ccgctcccgc
    50041 cggactcctc ccgcacgtac acgccgccga gccccaggcc ggcggccttg cgcagcacgt
    50101 cgagcgggaa gtgcttgtcc cggtcccagg cgacggcgtg cggggcgagg tggtcctggg
    50161 cgaagtccag ggtcgtctcg acgagggcca gttggtcctc gctgagctgg gtcgtggtca
    50221 ccgcgcccac ctcatcgccg ggatcgtgaa gctcgcgccc tcgcggcggc cggcgggcca
    50281 tcgggaggtg acggtcttgg tgcgggtgta gaagcggatg gcgtccggtt cgtgctggtt
    50341 gaggtcgccg aagccggagc gcttccagcc gccgaaggtg tggtaggcga ccggcaccgg
    50401 aatgggcacg ttgacgccga ccatgccggt gttcacccgc cgggtgaagt cgcgcgccgt
    50461 gtcgccgtcc cgggtgaaca gggcgacgcc gttgccgaag gcgtgctcgc cgggcagccg
    50521 cagggcctcc tcgtagtcgg cggcccggac gacggacagc acgggcccga aggtctcctc
    50581 ctggtagatc cgcatgtccg gcgtgacgcg gtcgaagagc gacgccccgg cgaagcaccc
    50641 gccctcgtgg cccggcagga cgaagtcccg cccgtcgacg tcgagttcgg cgccctcggc
    50701 catcaccgca tcggcagagg aacgcacccg gtccacggcg tcccggccga ccagcggccc
    50761 gaagtccgcc tcggggtcgt cgctccggcc cacccgcagc cgtccgatgc gctccgccag
    50821 tcgcgcgacc agggcctcgg cggtggcctc gccgacgggg accgccacgg agaccgccat
    50881 gcggcgctcg cccgccgagc cgtagccggc gccgatcagc gcgtccacgg cctggtcgag
    50941 gtcggcgtcc ggcatcacga tcaggtggtt cttggcgccg ccgaagcact gcgcgcgctt
    51001 gccgtgggcg gcggcggtgg cgtacacgtg ggcggcgatg ggcgtggagc cgacgaagcc
    51061 gagc
//
