LOCUS       NZ_CP090418            22898 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain WGB211 chromosome, complete
            genome.
ACCESSION   NZ_CP090418
VERSION     NZ_CP090418.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4913676)
  AUTHORS   Ma,Y.
  TITLE     Complete genome sequence analysis of long-chain alkane degrading
            bacterium Stenotrophomonas maltophilia WGB211
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4913676)
  AUTHORS   Ma,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) College of Life Science, Northwest
            University, No. 229 Taibai Road, Xian, Shaanxi 710069, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.2
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 344.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021441865.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 14:29:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,549
            CDSs (total)                      :: 4,458
            Genes (coding)                    :: 4,408
            CDSs (with protein)               :: 4,408
            Genes (RNA)                       :: 91
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 50
            CDSs (without protein)            :: 50
            Pseudo Genes (ambiguous residues) :: 0 of 50
            Pseudo Genes (frameshifted)       :: 25 of 50
            Pseudo Genes (incomplete)         :: 28 of 50
            Pseudo Genes (internal stop)      :: 6 of 50
            Pseudo Genes (multiple problems)  :: 7 of 50
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:49:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1729628
            Orig. end                         :: 1752526
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090418.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from School of Life Sciences,
            Northwestern University, China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22898
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="3"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22898
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12898](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12898
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     gene            307..822
                     /locus_tag="LYZ64_RS08255"
     CDS             307..822
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646745.1"
                     /locus_tag="LYZ64_RS08255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_010484296.1"
                     /transl_table=11
                     /translation="MRQSVSTVRVLSYALLAVAVAAGTTGCFKRGVKGDYALAPEMRPL
                     EVPPDLNLPTTTGDNKVPTLASATKPAAPAAAAPAVGNTGFTIAGGKDEAFAKVGTALE
                     GVEGVTIASRAQLLGSYDVAYEGSNFLVRVVAVDAGAYISAVDPRGLPATAEAPVKLIA
                     ALKAKLAQ"
     gene            complement(973..1296)
                     /gene="fdxA"
                     /locus_tag="LYZ64_RS08260"
     CDS             complement(973..1296)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /function="Ferredoxin"
                     /gene="fdxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005994928.1"
                     /locus_tag="LYZ64_RS08260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin FdxA"
                     /protein_id="WP_004153066.1"
                     /transl_table=11
                     /translation="MPFVVTENCIKCKHTDCVEVCPVDCFHEGPNFLVIDPDECIDCTL
                     CEPECPVNAIFPEDDVPAGQESFVALNAELAKEWPVLTVRKDPPADAGEWDGKPDKLKL
                     LER"
     gene            1489..2913
                     /locus_tag="LYZ64_RS08265"
     CDS             1489..2913
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661180.1"
                     /locus_tag="LYZ64_RS08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_164089781.1"
                     /transl_table=11
                     /translation="MSPAQPNIASHGGENTAFIVLISCVATLGGFLFGFDSGVINGTVD
                     GLRQAFNSSEAALGFEVASMLLGCAIGAFLAGWLGDRLGRRGVLIASALMFLVSALGAG
                     AAHASWLFIAARVLGGFAVGAASVMSPAYIAEVASARYRCRLATVQQMAIICGLFAAFL
                     SNYLLARAAGASTEPLWLGHEAWRWMFWMQALPSGLFLLLLLVIPESPRFLVLKGRQQQ
                     ARAVLSRLYGEAAAAAKQAEIEASLAQDQHKPRFADLRDTVSGKLRPILWVGIGLAMFQ
                     QLVGINVVFYYGAVLWQAVGFSESDALLINVLSGALSIGACLLTVLLIDRIGRKPLLWI
                     GSVGMSVALVLMVVAFASGSLADGRLQLSDGMGRLALVAANVYVVFFNMSWGPVMWVML
                     GEMFPNQIRGPALAVAGAAQWTSNFAITVTFPMLLAGIGLAGAYGIYTVAAILSIFFVV
                     RYVRETKGKELEQMEG"
     tRNA            complement(3172..3246)
                     /anticodon=(pos:complement(1732839..1732841),aa:Glu,
                     seq:ctc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LYZ64_RS08270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Glu"
     gene            complement(3172..3246)
                     /locus_tag="LYZ64_RS08270"
     misc_feature    3190..3205
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.79"
                     /tool="antismash"
     gene            3293..4678
                     /gene="pcnB"
                     /locus_tag="LYZ64_RS08275"
     CDS             3293..4678
                     /EC_number="2.7.7.19"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:1990817 - poly(A) RNA polymerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006378 - mRNA polyadenylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pcnB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005409056.1"
                     /locus_tag="LYZ64_RS08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="WP_164089780.1"
                     /transl_table=11
                     /translation="MPLGNPETSTGSANIISPATSPFSLRVIPRDQHTISRKDISPNAL
                     RVLYRLRDAGFGAYLVGGAVRDLLVNGQPKDFDVATDATPEQVKQLFRNCRLIGRRFRL
                     AHVVFGREIIEVATFRANSDDGSGDREMENGMLVRDNVYGTIEDDAIRRDFTCNALYYA
                     IEDFSVRDYTGGFEDVQARLMKLIGDPEQRYREDPVRMLRAVRLAAKLGFQIEEGTAAP
                     IPQLAGLLNEAAPARLFEEVLKLFLSGHGVASFEGLERYGLLDVLFPESAKALKSNRTG
                     ALRRMLVEGLANTDARVANDEPVSPSFLFALLLWPAFCRAQATLLKQGVAPEEAQRRAA
                     DRVTVQQLSTIALPRRFSLPMQEIWLLQSRFGSRQRKRVFRTLTHPRFRAAFDFLSLRQ
                     VASSEHAADVEFWREAQAQSGRELESSLDVVHSEEGDDESGAPRKRRRRRRRPGAPAGA
                     AGE"
     gene            4682..5167
                     /gene="folK"
                     /locus_tag="LYZ64_RS08280"
     CDS             4682..5167
                     /EC_number="2.7.6.3"
                     /GO_function="GO:0003848 -
                     2-amino-4-hydroxy-6-hydroxymethyldihydropteridine
                     diphosphokinase activity [Evidence IEA]"
                     /GO_process="GO:0009396 - folic acid-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="folK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338321.1"
                     /locus_tag="LYZ64_RS08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="WP_106467699.1"
                     /transl_table=11
                     /translation="MTLAWIGLGANLGDAAATVGAAIAALDDLPGTRLSQASRLYATPA
                     WGNEDQPPFVNAVAAVETTLPADTLLQAMLALEQRFGRVRDPAVHWGPRALDLDLLLYG
                     AQVLVQPGLQVPHPYLHERAFVLVPLAEIAPDLAIPGHGRVRDAVMRVDACGIAPIG"
     gene            5202..6017
                     /gene="panB"
                     /locus_tag="LYZ64_RS08285"
     CDS             5202..6017
                     /EC_number="2.1.2.11"
                     /GO_function="GO:0003864 - 3-methyl-2-oxobutanoate
                     hydroxymethyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416119.1"
                     /locus_tag="LYZ64_RS08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-methyl-2-oxobutanoate hydroxymethyltransferase"
                     /protein_id="WP_033833063.1"
                     /transl_table=11
                     /translation="MSTHADSKPWTVPALAEAKRNGQKLVMLTAYDAGFARTFDANGVD
                     LILIGDSLGMVVQGHDSTLPVTVADMVYHTRAVARVLQRALLVADLPFGADATPERALD
                     ASLQLLQAGAEMVKIEGAGFKVDIIRYLVEREIPVCAHLGLTPQSVLRLGGFKIQGRGD
                     AARQLVEDARAVAAAGASIMVLECVPTPVAAEVTAAVEVPTIGIGAGPQCDGQVLVLHD
                     FLGLDSGHRRPKFVKDFLAEGGSVAGATRAYADAVRDGSFPDEQHAYAQ"
     gene            6014..6853
                     /gene="panC"
                     /locus_tag="LYZ64_RS08290"
     CDS             6014..6853
                     /EC_number="6.3.2.1"
                     /GO_function="GO:0004592 - pantoate-beta-alanine ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011259031.1"
                     /locus_tag="LYZ64_RS08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="WP_106467700.1"
                     /transl_table=11
                     /translation="MIQTFNELGALRGQIAQWKREGLRVALVPTMGNLHGGHHSLVTLA
                     RQYADKVVASIFVNPTQFGPNEDFSRYPRTPEADVAGLEQAGCDAVWLPSVEVMYPLGV
                     DKTTQMHAPGVSEVLEGASRPGHFDGVCTVVARLFLQVQPDVAVFGRKDYQQLAVIKQM
                     VAELSFPIQIVGADIVRDEDGLAKSSRNQYLSAEQRPLATTIHRTLLGMREGYVAGHAR
                     DRIEADATAALQAAGFQVDYAVLRTPELAEPTFDGGGRVALIAARLGTTRLIDNLEF"
     gene            6919..7416
                     /locus_tag="LYZ64_RS08295"
     CDS             6919..7416
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412963.1"
                     /locus_tag="LYZ64_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_106467701.1"
                     /transl_table=11
                     /translation="MTPRTTDAGRLAQASILAVLAAGMLPAQLFGGLLFTLEFRRTPMP
                     ALTGGGMMFVLAVSNAIAVLLPMALILQSQQRLRRTGFVLVGFGLGALAMATCTWPGAD
                     NGPLLQRLRYVDTFDVISYALQVLAAGGFGLVAGLAFHTVFRLSLVGSSGHAAAPLPGE
                     RA"
     gene            7504..7884
                     /gene="panD"
                     /locus_tag="LYZ64_RS08300"
     CDS             7504..7884
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036943.1"
                     /locus_tag="LYZ64_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_005409061.1"
                     /transl_table=11
                     /translation="MHLSLLKTKIHRATVTHSELNYEGSIAIDDNLLAATGIREFEQVH
                     IWDVTNGARFSTYAIRAEAGSGVVSLNGGAARHVQVGDIIIIAAFASMTEQEADSFKPK
                     LVYVDGKNQITHTNDTIPTQAA"
     gene            7881..9395
                     /gene="pgi"
                     /locus_tag="LYZ64_RS08305"
     CDS             7881..9395
                     /EC_number="5.3.1.9"
                     /GO_function="GO:0004347 - glucose-6-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300464.1"
                     /locus_tag="LYZ64_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="WP_164089779.1"
                     /transl_table=11
                     /translation="MTTNNGFDSLHSHAQRLKGASIPSLLAAEPGRVQDLALRVGPLYV
                     NFARQKYDAAALQALLALAADRDVGGAITRLFRGEQVNLTEGRAALHTALRGDVVDAPV
                     AAEAYATARGIRQRMGVLVRALEDSGVTDVVSVGIGGSDLGPRLVADALRPVTGARLRV
                     HFVSNVDGAAMQRTLATLDPAKAAGILISKTFGTQETLLNGQILHDWLGGSERLYAVSA
                     NPERAAKAFAIAADRVLPMWDWVGGRYSLWSAVGFPIALAIGFERFEQLLEGAAQMDAH
                     ALDAPLERNLPVLHGLTDIWNRNLLGHATHAVMTYDQRLALLPAYLQQLVMESLGKRVQ
                     RDGQPVTTDTVPVWWGGAGTDVQHSFFQALHQGTSIVPADFIGCVHNDDPYTINHQALL
                     ANLLAQTEALANGQSSDDPHRDYPGGRPSTLILLDALTPQALGALIAMYEHAVYVQSVI
                     WNINAFDQFGVELGKQLASGLLPALQGEDVAIADPMTREILAQLKG"
     misc_feature    complement(9542..9558)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.78"
                     /tool="antismash"
     misc_feature    9705..9723
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: medium, score: 27.95"
                     /tool="antismash"
     gene            9712..9918
                     /locus_tag="LYZ64_RS08310"
     CDS             9712..9918
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268305.1"
                     /locus_tag="LYZ64_RS08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6229 family protein"
                     /protein_id="WP_049423517.1"
                     /transl_table=11
                     /translation="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGAAATESALTSASD
                     TLITGGGTECTTTMSVVNHCLCC"
     CDS_motif       9712..9810
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGA"
                     /locus_tag="LYZ64_RS08310_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9811..9918
                     /prepeptide="core"
                     /locus_tag="LYZ64_RS08310_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.70"
                     /molecular_weight="3233.6"
                     /monoisotopic_mass="3231.5"
                     /core_sequence="AATESALTSASDTLITGGGTECTTTMSVVNHCLCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MDLNDDVVSGWLNGSDDVDGCANPAGSLFIYGA"
                     /leader_location="[9711:9810](+)"
                     /alternative_weights="3251.6"
                     /alternative_weights="3269.6"
                     /alternative_weights="3287.7"
                     /alternative_weights="3305.7"
                     /alternative_weights="3323.7"
                     /alternative_weights="3341.7"
                     /alternative_weights="3359.7"
                     /alternative_weights="3377.8"
     gene            10001..12898
                     /locus_tag="LYZ64_RS08315"
     CDS             10001..12898
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019338325.1"
                     /locus_tag="LYZ64_RS08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_164089778.1"
                     /sec_met_domain="DUF4135 (E-value: 5.4e-80, bitscore:
                     267.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.6e-32, bitscore:
                     110.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTASPAAAAFARITEHFLVHARAALAAGLHDPAIALQPGERELLH
                     AQGDAALREHAQLKLNRVLLLELHAAARGGDIGPLDSAGALDEFVALATSEGFHEHLQR
                     RYPVLLPRLSRMLEGQCAAVVELAARIGSDRALLTDLLDAPAGALRAIALGRGDLHGGG
                     RTVARLQFDGGVLMYKPRSLRIDAALDGLLAAVFGDGPDRVRVPRVVDRGSHGWAAFAA
                     HRHCADDEELRAYYRGLGHWLAILRLVGGTDIHLENLIAVGPVPVVIDAESVFSQVIDV
                     EPSGLGDAYDTAIKLMRNSVLRTGIVPFRTTGLGMEGVDLSAAGALPGEQPRVQVPVIV
                     EDGTGPARLGMVEAEVAIAQNHPSPQPDVSLYWDHISEGFIDASRRLRALDAKGELMPL
                     LAAFEGCQVRDVRRPTMAYAELGRMLWHPASLHKEAQAVERAIDLLVRNAAVSPAAPSD
                     LETVRGEVDDLRHGDIPIFTSQLDATRIRSIADNWRAMRIDLEDVTIRSTLVATDLNQH
                     ALARAEARSGYSYAAQHPRADDLDLRRRTLAARAVENLLRLAVHGEDGSMTWITPEVTR
                     TGWTVQPVQPDLYFGLGGIAFALAAYRREVEQGRADPVAGLDPAIEGAIAVFQTMCERH
                     PAGIDGGFVGTGSQIWTLLALHDLLQRPALLALAERCAEGVERRGFQGPVKFELIDGVS
                     GMILPLLALAGATGNARWLELAAAAGRRMQEAAIVDADGARWPTPQFREPIGGFGHGAM
                     GMGWALARLARSDAGSVPERAAWRQLAEGAFAFQAALFEPHTGHWRDIHLQDGQKNFPT
                     WCHGSVGIGLAAADLYARTGDPAQLRDMRRAVADARGKWGFSHTLCHGDVSTRELLVLA
                     AALDPEGCPYPQDEAAIEIVSSIEEHQGMVGGLTRAAFTPGLMIGLAGAIYGFLRMHPA
                     CALPSPLLQETAAARVDAPASRSSAAQDRPALAEV"
     gene            complement(12920..13489)
                     /locus_tag="LYZ64_RS08320"
     CDS             complement(12920..13489)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012510702.1"
                     /locus_tag="LYZ64_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_012510702.1"
                     /transl_table=11
                     /translation="MSLHHSTLGLLVDDDELYLRTLQRSLARKGLETQTAQDAASALAL
                     ARQHPPAFALIDLKLGSDSGLALIQPLRALRADMRILLVTGYASIATAVEAIKLGADDY
                     LPKPATVPMILRALGEEDDGPADDGEMEVPDAMTPISRLQWEHIQQAMHETGGNVSAAA
                     RLLGMHRRSLQRKLAKRPSPERDPSR"
     gene            complement(13486..14712)
                     /locus_tag="LYZ64_RS08325"
     CDS             complement(13486..14712)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019661188.1"
                     /locus_tag="LYZ64_RS08325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_106467704.1"
                     /transl_table=11
                     /translation="MTGPDAPFLQTLCSLRWLAVGGQAATILVATWVLGLPLPQLPLWA
                     GVAVLTLFNIYTQLRPEAADTAPLTAFGHILVDVIILTWMVGWSGGMANPFSSLFLILI
                     ALAAFALPLRWALAVALACLLGYAASGIFGQSLPDGYFRAQDLNRWGVVANFLISAAVV
                     LTFSTRLALALRQRELELSALRERFARNEGIVALATHAASVAHELNTPLATMTLLADDV
                     AERSEEPEVREDMETLRELLVQCRERVLALAAPASADAPGRSHSSAQQVLEQWRLVRPT
                     IDLHRNDDAPLRLPLDPGVGHLLMVLLNNAADAGEQAGRPRVDLDLRIEGDDLIGEVRD
                     YGHGFDARAAVLPGKLFGSSKSEGMGVGLALSHATIERLDGEMWMRPAQGAGSRVGFRL
                     PLAPREDTP"
     CDS             complement(14719..14832)
                     /gene="allorf_1744347_1744460"
                     /locus_tag="allorf_1744347_1744460"
                     /protein_id="allorf_1744347_1744460"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MHGRILPPASAFRVTRIQPAARLRPIVAGMCTRERIR"
     CDS_motif       complement(14746..14832)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MHGRILPPASAFRVTRIQPAARLRPIVAG"
                     /locus_tag="allorf_1744347_1744460_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14719..14745)
                     /prepeptide="core"
                     /locus_tag="allorf_1744347_1744460_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.20"
                     /molecular_weight="1046.3"
                     /monoisotopic_mass="1045.5"
                     /core_sequence="MCTRERIR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MHGRILPPASAFRVTRIQPAARLRPIVAG"
                     /leader_location="[14745:14832](-)"
     misc_feature    14782..14800
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.46"
                     /tool="antismash"
     gene            14827..16092
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="LYZ64_RS08330"
     CDS             14827..16092
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019300453.1"
                     /locus_tag="LYZ64_RS08330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_106467705.1"
                     /transl_table=11
                     /translation="MHDAVTRPTPPSDATAWPRRQTHAVQIGGVTVGGGKPVVVQSMTN
                     TDTSDVASSVKQVAELWRAGSEMVRLTVNTVEAAAAIPRIVDKLAMMGIDVPLIGDFHY
                     NGHQLLTAEPACAEALAKYRINPGNVGFGKKKDLQFAQLIEFAIRYNKPVRIGANWGSL
                     DQALAAKLMDENNLREQPWDAGRVLREALIRSALDSAEQAVELGLPRDRIVLSAKVSGV
                     QELIAVYRDLAQRSDFALHLGLTEAGIGSKGIVASSAALSVLLQEGIGDTIRISLTPEP
                     GQSRTQEVIVAQELLQTTGQRAFTPLVTACPGCGRTTSEFFQELAKVVQNHVREKMPLW
                     KIHHPGAENMTLAVMGCIVNGPGESRHANIGISLPGTGETPAAPVFVDGEKKVTLRGDN
                     IAQEFVALIDDYVEHKYVRSAG"
     gene            16073..16822
                     /locus_tag="LYZ64_RS08335"
     CDS             16073..16822
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005409066.1"
                     /locus_tag="LYZ64_RS08335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_088025646.1"
                     /transl_table=11
                     /translation="MSEAPDKPAILAAPESASGFRHWMARNAWRLVLLFGGVLLPLAGF
                     VALADEVHEFESFHFDAPLLWQMHGLHSPWLDRFFVLISKLGYEWFLIPADVLIIGVLL
                     GYRRWREATFVAVSFVGSALLNMGSKHFFQRQRPSLWESIAPESTFSFPSGHAMGSMTL
                     AVTLVLLAWNTRWRWPVLLLAPAFSLLVSVSRVYLGVHYPSDILAGWCAALVWVVGCYL
                     VMFSRRHPWRRHGSPPAKASEASSQGV"
     gene            17023..17670
                     /locus_tag="LYZ64_RS08340"
     CDS             17023..17670
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /function="Response regulator containing a CheY-like
                     receiver domain and an HTH DNA-binding domain"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011408972.1"
                     /locus_tag="LYZ64_RS08340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator"
                     /protein_id="WP_004153112.1"
                     /transl_table=11
                     /translation="MTIRVYLVDDHALVRTGMKMILSGETDIEVVGEAETGEDALREVR
                     QLLPDVVLCDLHLPGVSGMEVTERIVRSHRNTRVVIVSVLEDGPLPKRLLEAGAAGYIG
                     KGCDAQELLRAVRDVAGGRRYLGTSIAQNLALSTVEGNGSPFDSLSPRELEVALLLTQG
                     LRQEDIARRLSLSAKTVNTHKARLFEKMGIHDNIALARMASQYGLVDPARPL"
     gene            complement(18004..18663)
                     /locus_tag="LYZ64_RS08345"
     CDS             complement(18004..18663)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0016830 - carbon-carbon lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016832 - aldehyde-lyase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016833 - oxo-acid-lyase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /function="2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265926.1"
                     /locus_tag="LYZ64_RS08345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_004153124.1"
                     /transl_table=11
                     /translation="MGIEQHQVKAAELLRAAGILPVVTIHTLDQARAVSAALLEGGLPA
                     IELTLRTPVAMEALAMLKRELPDVVVGAGTVLTVEQMQQSIDAGADFLVTPGTPPALAD
                     ALAAAPLPVVPGAATPTELLSLYARGFRVCKLFPATAVGGLAMIKGLAGPVADLKLCPT
                     GGITENTAAEYLEQKNVVCIGGSWMVPGNWIANGEWDKVRASAADAAKIIKRVRGH"
     misc_feature    complement(18631..18640)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(18861..18876)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.9"
                     /tool="antismash"
     gene            complement(18869..20785)
                     /gene="edd"
                     /locus_tag="LYZ64_RS08350"
     CDS             complement(18869..20785)
                     /EC_number="4.2.1.12"
                     /GO_function="GO:0004456 - phosphogluconate dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="edd"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015472018.1"
                     /locus_tag="LYZ64_RS08350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphogluconate dehydratase"
                     /protein_id="WP_164089776.1"
                     /transl_table=11
                     /translation="MSLHPQLQAITERVIRRSAASRAAYLAAIDASLREGPFRSRLSCG
                     NLAHGFAACGGTDKSRLRGGVTPNLGIITAYNDMLSAHQPFETYPEQIRDIARELGATA
                     QVAGGVPAMCDGVTQGRGGMELSLFSRDVIAQATAIGLSHDMFDTTVYLGVCDKIVPGL
                     LIGALAFGHLPAVFVPAGPMTPGIPNKQKAEVRERYAAGEATREELLEAESASYHGAGT
                     CTFYGTANSNQVLLEAMGVQLPGASFVNPGTPLRDALTREATERALDITALGDDFRPLG
                     RIIDERAIINAVIALMATGGSTNHTIHWIAVARAAGIVLTWDDFDELSQLIPLLARVYP
                     NGDADVNRFAAAGGPAFVFGELIKAGLMHGDLVSVARGGMADYAREPQLRDGQLVYLPG
                     LERSADEEVVRGVDNPFEHQGGLRLLRGNLGKSLIKLSAVKPQYRTIEAPAVVVDAPQV
                     LNKLHAGGLLPEHFVAVVRYQGPRANGMPELHSLAPLLGLLQNQGRRVALVTDGRLSGA
                     SGKIPAAIHVTPEAARGGPLAKVREGDMIRLDGEAGTLEVLVDAAEWAARPLAPNTAPA
                     AHDLGRNLFAINRRVVGPADQGAISISCGPAAADGGPWDYDAEYELGHDAAAAAAPHEA
                     KDA"
     misc_feature    20744..20757
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.77"
                     /tool="antismash"
     gene            complement(20844..21566)
                     /gene="pgl"
                     /locus_tag="LYZ64_RS08355"
     CDS             complement(20844..21566)
                     /EC_number="3.1.1.31"
                     /GO_function="GO:0017057 - 6-phosphogluconolactonase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pgl"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479767.1"
                     /locus_tag="LYZ64_RS08355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-phosphogluconolactonase"
                     /protein_id="WP_088025648.1"
                     /transl_table=11
                     /translation="MSPTFHDDRIEFINHGDADGWIEAVAAEMAQTLNHDINEVGRARI
                     LLSGGTTPAPVYQALAELDVHWDRVEVSLADERWLSPQDRDSNAWLVREHLLKRAEGAH
                     FDPLVRVGKPLPECVYTANLQAQHSQPPSLVALGMGNDGHTASLFPGSKDLARALESTL
                     PYAALDATGCPGANQWPLRITLTPHGLRQCRQRLLLLRGKQKLQVLRQALDSNDAQQYP
                     ILNAINLEGARLRVHWAD"
     gene            complement(21563..22570)
                     /gene="glk"
                     /locus_tag="LYZ64_RS08360"
     CDS             complement(21563..22570)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005416128.1"
                     /locus_tag="LYZ64_RS08360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucokinase"
                     /protein_id="WP_010484331.1"
                     /transl_table=11
                     /translation="MSASSQPVLVADIGGTNARFALADTSQDAPLQKDSIREYAVAEFP
                     SLGDAARHHLEQIGATASRGVFAVAGRVDGDEARITNHPWVISRSRTAAMLGFDELHLI
                     NDFAAQAMAISLLQPDDVVQVGGAAWVPGKPGQPRNYAVIGPGTGLGVGGLILRHGRCY
                     PLETEGGHVSFPPGTPEEIRILEILSEQFGRVSNERLICGPGLVNIHRAVCEMAGIDPG
                     QLQPVDVTARALHGDPQAMRTVDVFCAVFGAIAGDLVLTQGAWDGVFLTGGLTPKMLDS
                     LQHSGFRQRFEHKGRFSSIMARVPSLAVMHPHAGLLGAAAYAADAERDAPGVAA"
     misc_feature    complement(22772..22787)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    22773..22786
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.0"
                     /tool="antismash"
ORIGIN
        1 ctccaacgtg ctgcccggcg cctaccgccg gatgtgcgag ctggccgccg cccatgacca
       61 cgaagccacc gagtcctggg atgcgcgcct gcatccgttc catgagttct gcggcgttga
      121 accgaatccg atcccggtca aggcgttgct gcgccgtatc ggcatcggcc acgacctgcg
      181 cctgccgctg ctgccactgt cggcgccgca tcatccggcg gccgaccacc ttgccggcga
      241 catcgccgcc ctcgaagccc tttccagcca ctgaccttcc gtcttggtct gacccaggag
      301 attcacatgc gtcaatccgt atccaccgtc cgcgtgctgt cctacgccct gcttgcggtg
      361 gccgttgccg ccggcaccac cggttgcttc aagcgtggtg tcaagggcga ctacgccctg
      421 gccccggaaa tgcgtccgct ggaagtgccg ccggacctga acctgccgac caccaccggt
      481 gacaacaagg tgccgacgct ggcatcggcg accaagccgg ccgcgcctgc ggctgcggcc
      541 ccggccgtgg gcaacaccgg tttcaccatc gccggtggca aggacgaggc tttcgccaag
      601 gtcggcaccg cgctggaagg cgtggaaggc gtgaccatcg ccagccgcgc gcagctgctg
      661 ggctcgtatg acgtggccta cgaaggcagc aacttcctgg tccgcgtggt cgccgtcgat
      721 gccggcgcct acatctccgc ggtcgacccg cgtggcctgc cggccactgc agaagcgccg
      781 gtgaagctga tcgccgcgct gaaggcgaag ctggcccagt aagggccggt cgggtgggtg
      841 cggcccaggt ccgcacccgc ccgggtagag gccgaccttg gtcggcgctt ctgtgccaac
      901 caaggttggc acccaccgag aacaaaaaag ggcgcccacg gcgccctttt ttgttgccgc
      961 tccaggcgct tctcagcgct ccagcagctt cagcttgtcc ggcttgccgt cccattcgcc
     1021 ggcgtcggcg ggcgggtcct tgcgcacggt caataccggc cactccttcg ccagctcggc
     1081 gttgagggcg acgaagcttt cctggccggc gggaacatcg tcctccggga agatcgcgtt
     1141 gaccgggcat tccggttcgc agagggtgca gtcgatgcac tcatccgggt cgatcaccag
     1201 gaagttcggg ccttcgtgga agcaatccac ggggcacact tccacgcaat cggtgtgttt
     1261 gcacttgatg cagttttcgg tgacgacaaa gggcatgggc tgggggtgga tcgattcctg
     1321 aacccgccaa ttctagaaca ggttggcccc cggtgtcggc gcggggcgga aatcgggcgt
     1381 ctggcaggcg cggccgtggc ggtcattggc ggcagggcca ggcctgtgcg acgctgcggg
     1441 tcagccggcc gcgtcggatg gccggacccc ttcccagcag gatcgttcat gtccccagcc
     1501 cagcccaaca tcgcctccca tggcggtgag aacactgcat tcatcgtcct gatcagctgc
     1561 gtggccaccc tgggcggatt cctgttcggc ttcgacagtg gtgtcatcaa tggcacggtc
     1621 gatggcctgc gccaagcctt taactccagc gaggcggcgc tcggtttcga agtcgcctcg
     1681 atgctgctgg gctgcgcgat cggtgccttc ctggccggtt ggctgggaga tcgcctgggc
     1741 cgtcgtggcg tgctgatcgc ctcggcgctg atgttcctgg tctcggcgct gggtgccggt
     1801 gccgctcacg cctcctggct gttcattgcc gcacgcgtgc tcggcggctt cgcggtgggg
     1861 gcggccagtg tgatgtcgcc ggcctacatc gccgaagttg cctcggcgcg gtatcgctgc
     1921 cggctggcca cggtgcagca gatggcgatc atctgcggcc tgttcgccgc cttcctcagc
     1981 aactacctgc tggcccgtgc cgctggggcg tcgaccgagc cgctatggct gggccatgag
     2041 gcctggcgct ggatgttctg gatgcaggca ctgccgtcgg ggctgttcct gctgttgttg
     2101 ctggtgattc cggaaagccc gcgcttcttg gtcctgaagg ggcgtcaaca gcaggcgagg
     2161 gcggtactgt cgcggctgta cggcgaggcc gcagcggcag ccaagcaggc cgagatcgaa
     2221 gccagcctgg cccaggacca gcacaagccg cgctttgccg acctgcgcga cacggtcagc
     2281 ggcaagctgc gcccgatcct gtgggtcggc atcggcctgg ccatgttcca gcagctggtg
     2341 ggcatcaacg tggtgttcta ctacggtgcg gtgctatggc aggcggtggg tttctcggaa
     2401 agcgatgcgc tgctgatcaa cgtgctgtcc ggcgcgctga gcatcggcgc ctgcctgctg
     2461 acggtgctgt tgatcgaccg catcgggcgc aagccgctgc tgtggatcgg ctcggttggc
     2521 atgtcggtgg cgctggtgct gatggtggtc gccttcgcca gtggcagcct ggccgatggt
     2581 cggctgcagt tgtccgacgg catggggcga ctggcgttgg ttgcagccaa tgtctacgtg
     2641 gtgttcttca acatgtcctg gggcccggtg atgtgggtga tgctgggcga aatgttcccg
     2701 aaccagatcc gcggcccggc gttggccgtt gccggtgcgg cgcagtggac atcgaatttc
     2761 gcgatcaccg tgaccttccc gatgctgctg gccggcatcg gcctggccgg ggcctacggc
     2821 atctatacgg tcgcggcgat cctctcgatc ttcttcgtgg tccgctatgt gcgcgagacc
     2881 aagggcaagg agctggagca gatggaaggc tgacgtcgcc cggcttcggt tgcattccgt
     2941 tggcgcctgc ttgtcccgag tttgaggggg caggccgccc tctccaggac acgcaaaagc
     3001 ccatcgagcc ccatggatgg gttcacggcg tgtcctgccc tgggtgaccc caccggctca
     3061 agcagattgc agggaggcgc caaagcgacc aacccgaccg cagccaccgg caaacccgga
     3121 aaacagaaaa gcccgcgcaa ggcgggcttt ttcggttcct gctgcggcga ctggcgctcc
     3181 ctaggggact cgaacccctg ttttagcctt gagagggcca cgtcctaacc actagacgaa
     3241 gggagcgtaa ctgtgtcgct gccgaggcag gagcgctagt atatgcacct cgatgccatt
     3301 gggcaatccc gaaacttcaa ccggaagcgc caacatcatt tcccctgcta catcaccgtt
     3361 cagcctgcgc gtcatcccgc gcgaccagca cacgatctcc cgcaaggaca tcagcccgaa
     3421 cgccctgcgc gtgctttatc gcctgcgcga tgccggcttc ggcgcctacc ttgtcggcgg
     3481 cgcggtgcgc gatctgctgg tcaatggcca acccaaggat ttcgacgtgg ccaccgacgc
     3541 cacgcccgaa caggtcaagc agctgttccg caactgccgc ctgatcggtc gccggttccg
     3601 ccttgcccac gtcgtgttcg gccgcgagat catcgaagtc gccaccttcc gtgccaacag
     3661 cgatgacggc agcggcgacc gcgagatgga aaacggcatg ctcgtgcgcg acaacgtgta
     3721 cggcaccatc gaagatgacg ccatccgccg cgacttcacc tgcaacgccc tgtactacgc
     3781 catcgaggac ttctcggtgc gtgattacac cggcggcttc gaagacgtcc aggcgcgcct
     3841 gatgaaactg atcggcgacc ccgagcagcg ctatcgcgaa gacccggtgc gcatgctgcg
     3901 tgcggtgcgc ctggcggcca agctcggctt ccagatcgaa gagggcaccg ccgcgccgat
     3961 cccgcagttg gctggcctgc tcaacgaagc cgcgccggca cgcctgttcg aggaagtgct
     4021 caagctgttc ctgtccgggc acggcgtggc cagcttcgaa ggccttgagc gctacggcct
     4081 gctcgacgtg ctgttcccgg aaagtgccaa ggcgctgaag tccaaccgca ccggcgcgct
     4141 gcgccgcatg ctggtcgagg ggctggccaa cactgatgca cgtgtggcca acgacgagcc
     4201 ggtctcgccg tcgttcctgt tcgcgctgct gctgtggccg gcgttctgcc gcgcccaggc
     4261 aaccctgctc aagcagggtg tggcaccgga agaggcgcag cgccgtgccg ccgatcgcgt
     4321 cacggtgcag cagctgagca ccatcgcgct gccgcgccgt ttctcgctgc cgatgcagga
     4381 gatctggctg ctgcagtcac gtttcggctc gcgccagcgc aagcgcgtgt tccgtaccct
     4441 gacccatccg cgtttccgcg ctgcgttcga cttcctcagc ctgcgccagg tggcctcgtc
     4501 cgagcacgcc gccgacgtcg agttctggcg cgaggcgcag gcgcagtccg gccgcgagct
     4561 ggaatcgtcg ctggacgtgg tgcacagcga agagggtgat gacgagagcg gggcaccgcg
     4621 caagcgccgc cgtcgccgcc gtcgtccggg cgcgccggcc ggtgcggctg gcgagtaaac
     4681 gatgaccctt gcctggatcg gcctcggcgc caaccttggc gacgcggccg ccaccgtcgg
     4741 cgcggcgatc gccgcgctcg acgacctgcc cggtacgcgc ctgagccagg cgtcgaggtt
     4801 gtacgccacc ccggcttggg gcaatgaaga tcagccgccg ttcgtcaacg cggtggctgc
     4861 ggtcgagacc acgctgcccg ccgatacgct gctgcaggcg atgctggcgc tggagcagcg
     4921 ttttggtcgc gtacgcgatc cggcggtgca ctggggcccg cgcgcgctgg acctggacct
     4981 gctgctgtat ggcgcgcagg tgctcgtcca gcctggtctg caggtgccgc atccctacct
     5041 gcacgagcgt gccttcgtgt tggtgccgct ggccgaaatc gcgccggatc tggccattcc
     5101 cggccatggc cgcgtgcggg atgcagtgat gcgggtggat gcctgcggga ttgcgccgat
     5161 agggtgataa tgcccgggtt atctcccccg gttatcagca catgagcacc cacgcagaca
     5221 gcaagccctg gaccgttccc gccctggccg aggccaagcg caatggccag aagctggtca
     5281 tgttgaccgc ctacgacgcc ggcttcgccc gcactttcga cgccaatggc gtcgacctga
     5341 tcctgatcgg cgattcgctg ggcatggtcg tgcagggcca tgattcgacc ctgccggtga
     5401 ccgtggccga catggtctat cacacccgcg ccgtggcccg tgtgctgcag cgtgcgctgc
     5461 ttgtggccga cctgccgttc ggtgccgatg ccaccccgga gcgcgcgctg gatgcatcgc
     5521 tgcagctgct gcaggccggt gccgagatgg tcaagatcga aggtgccggt ttcaaggtcg
     5581 acatcatccg ttacctggtc gagcgtgaga ttccggtctg cgcgcacctg ggcctgaccc
     5641 cgcagtcggt gctgcgcctg ggcggcttca agatccaggg gcgtggcgat gccgcgcgcc
     5701 agctggtgga agatgccagg gccgtggccg ctgccggcgc cagcatcatg gtgcttgaat
     5761 gcgtgccgac cccggtcgcc gccgaagtga ccgctgcggt agaagtgccg accatcggca
     5821 ttggcgcagg cccgcagtgc gatggccagg tcctggtgct gcacgatttc ctcggtctgg
     5881 acagtggtca tcgccgtccc aagttcgtca aggatttcct tgccgaaggc ggttcggtgg
     5941 ccggtgccac ccgcgcctat gccgacgcgg tgcgcgacgg cagtttcccc gacgaacagc
     6001 acgcgtacgc ccaatgatcc agaccttcaa cgagctcggc gcgctgcgcg ggcagatcgc
     6061 ccagtggaag cgcgagggcc tgcgcgtggc gctggtgccg accatgggca acctgcatgg
     6121 tggccaccat tcgctggtga ccctggcccg ccagtacgcc gacaaggtgg tggcgagcat
     6181 cttcgtcaac ccgacccagt tcgggccgaa cgaggatttc agccgctacc cgcgcacgcc
     6241 cgaggccgac gtggccgggc tggagcaggc cggctgcgat gcggtgtggc tgcccagcgt
     6301 cgaggtgatg tacccgctgg gcgtggacaa gaccacgcag atgcacgcgc ccggcgtcag
     6361 tgaagtgctg gaaggcgcca gccgaccggg gcacttcgat ggcgtgtgca cggtggtggc
     6421 gcgcctgttc ctgcaggtac agccggacgt ggccgtgttt ggccgcaagg actatcagca
     6481 actggccgtg atcaagcaga tggtggccga gctgtcgttc ccgatccaga ttgtcggcgc
     6541 ggacatcgtg cgcgacgagg atggcctggc caagagctcg cgcaaccagt acctgagcgc
     6601 cgaacagcgc ccgcttgcga ccaccatcca ccgcaccctg ctgggcatgc gcgaaggcta
     6661 cgtggccggg cacgcacgtg atcgcatcga ggccgacgcc acggcggcat tgcaggcggc
     6721 cggtttccag gtcgactatg cggtgctgcg gaccccggag ctggccgagc cgaccttcga
     6781 cggcggtggc cgcgtggcgc ttatcgccgc acggctgggt accacgcgcc tgatcgacaa
     6841 cctggagttc tgagccgcgt gcggctacgg ggcgcgcgca atgggcgcct ctcacatccc
     6901 acggacggga gactggacat gacaccccgc accactgacg ccggccgcct tgcccaggcc
     6961 tcgatcctcg ctgtgctggc tgccggcatg ctgccggccc agctgtttgg cggcctgttg
     7021 ttcacgcttg aattcaggcg cacgccgatg cctgcgctca ccggcggtgg gatgatgttc
     7081 gtgttggccg tgagcaatgc gatcgcggtg ttgctgccga tggcgctgat cctgcagtct
     7141 caacagcggc tgcgccgcac cggattcgtg ctggtcggct tcgggctggg tgcgctggcc
     7201 atggccacct gcacctggcc gggcgcggac aatggtccgc tgctgcagcg cctgcgctat
     7261 gtcgacacct tcgacgtgat cagctatgcc ttgcaggtgc tggccgcagg tggcttcggc
     7321 ctggtcgccg ggctggcctt ccatacggtg ttccggctgt ctctggtggg cagttccggg
     7381 catgccgcgg cgccgctgcc gggcgagcgc gcctgaacgg ccttcagcgt cctgctgcgg
     7441 ccccctgacg atggccaagc gggtgctaga atccgctctt tcctttgccg ttgcagcgcc
     7501 cccatgcacc tgtccctgct caagaccaag atccaccgcg ccaccgtcac ccattccgag
     7561 ctgaactacg aaggctcgat cgccatcgat gacaacctgc tggctgccac cggcatccgc
     7621 gagttcgagc aggtgcacat ctgggacgtg accaacggtg cgcgcttctc gacctacgcc
     7681 atccgcgccg aagccggcag cggcgttgtc tcgctcaacg gtggcgccgc gcgccacgtg
     7741 caggtcggtg acatcatcat catcgccgcg ttcgccagca tgaccgagca ggaagctgac
     7801 agcttcaagc cgaagctggt gtacgttgat ggcaagaacc agatcaccca caccaacgac
     7861 acgatcccga cccaggccgc atgacaacga acaacggatt cgactcgctg cactcccacg
     7921 cccagcgcct gaagggcgca agcattccca gcctgctcgc cgccgaaccc ggccgcgtgc
     7981 aggacctggc gctgcgggtc ggtccgttgt acgtcaactt cgcgcggcag aaatacgatg
     8041 ccgctgcgtt gcaggccctg cttgcgttgg ccgccgaccg tgatgtcggt ggtgccatca
     8101 cccgcttgtt ccgtggcgag caggtcaacc tgaccgaagg tcgcgccgcg ctgcataccg
     8161 cgctgcgcgg cgatgtggtc gatgcgccgg tggcggccga ggcctatgcc accgcgcgcg
     8221 ggatccgcca gcgcatgggc gtgctggtgc gcgcgctgga agacagcggc gtcactgacg
     8281 tggtcagcgt cggcatcggt ggttccgatc tcggtccgcg cctggtcgcc gatgcgttgc
     8341 gcccggtcac cggtgcgcgc ctgcgcgtgc atttcgtatc gaacgtggac ggcgccgcca
     8401 tgcagcgcac gctggccacg ctggatccgg cgaaggccgc cggcatcctg atctccaaga
     8461 ccttcggcac gcaggaaacc ctgctcaacg gccagatcct gcacgactgg ctgggtggca
     8521 gcgaacgcct gtatgcggtc agtgccaatc cggaacgtgc tgccaaggcc ttcgcgatcg
     8581 ctgccgatcg cgtgctgccg atgtgggact gggtcggtgg ccgttactcg ctgtggtcgg
     8641 cggtcggctt ccctatcgcg ctggcgatcg gcttcgagcg ctttgaacag ttgctggaag
     8701 gcgcggcgca gatggatgcg catgcgttgg atgcaccgct ggagcgcaac ctgccggtgc
     8761 tgcacggcct gaccgacatc tggaaccgca acctgctggg ccatgccacg cacgcggtga
     8821 tgacctacga ccagcgcctg gcgctgctgc cggcctacct gcagcagctg gtgatggaaa
     8881 gcctgggcaa gcgcgtgcag cgcgacggcc agccggtcac caccgacacc gtgccggtgt
     8941 ggtggggcgg cgcgggcacc gatgtgcagc acagcttctt ccaggcactg caccagggca
     9001 ccagcatcgt tccggccgat ttcatcggct gcgtgcacaa cgacgatccc tacacgatca
     9061 atcatcaggc cctgctggcc aatctgctgg cgcagactga agcactggcc aatggccaga
     9121 gcagcgacga cccgcaccgt gattacccgg gcggccgccc gagcacgctg atcctgctcg
     9181 acgcgctgac cccgcaggcg ctgggcgcac tgatcgccat gtacgaacac gccgtgtacg
     9241 tgcagtcggt gatctggaac atcaatgcct tcgaccagtt cggtgtcgag cttggcaagc
     9301 agctggccag tggcctgttg ccggcgctgc agggtgagga tgtggcgatt gccgatccga
     9361 tgacccgcga gatcctggcg cagctgaagg gctgacccgg cctgtggatg tgccggcgcc
     9421 ggccggccat cccatgcctt tcccgttgcg ttcgatccgg ccgcgcatga atgtccgcgc
     9481 ggccactcat tccgtgtcgt ttccgtgctg cgcatgcagc gcatccgcgt gcctgccgca
     9541 gcgcagcttg actgtgcatc gcgtgccaat gcagtgtgca cgggcggctg tacctgtcat
     9601 ccagtatcgc tcgcagcatg atgttgatgc cagggactgg ccgtatccga agggacgtgg
     9661 aatcgatcca tgtcctcaac gcctcatgtt gtgaatgaca ggagattgcg aatggatctg
     9721 aatgacgatg ttgtgtccgg ctggctcaat ggctcggacg atgtggatgg gtgcgccaac
     9781 cctgcgggtt cgctgttcat ctatggcgct gcggctaccg agtccgcact cacctcggcc
     9841 tccgacaccc tgatcaccgg tggtggcacc gagtgcacca ccacgatgtc cgtggtcaat
     9901 cactgcctgt gttgctgatg tagcccgagc cggcacgcag cgccttgcgg ctgcgtgccg
     9961 gcaactggaa cagacttccc gataccttgc agggggcgta atgaccgctt ctccggctgc
    10021 ggccgcgttt gcgcgcatca ccgaacattt ccttgtccat gcgcgtgccg cgctggcggc
    10081 cggcctgcat gaccctgcca ttgcgctgca gcccggtgag cgcgaactgc tgcacgcgca
    10141 gggcgatgcg gcgctgcgtg agcatgccca actcaagctc aatcgtgtgc tgttgctgga
    10201 actacatgcg gctgcgcgcg gcggtgacat cggcccgctt gacagcgccg gtgcgctgga
    10261 cgaattcgta gccctcgcca ccagcgaggg tttccatgaa catctgcagc gacgctaccc
    10321 ggtgctgttg ccgcggctgt cgcgcatgct cgaaggccaa tgcgcggccg tggtggagct
    10381 ggcggcccgg atcggcagtg atcgtgcgct gctgacggac ctgctcgacg ctccggcagg
    10441 ggcgctgcgt gcgatcgcgc tggggcgggg tgacctgcac ggcggcggcc ggaccgtggc
    10501 acggctgcag ttcgacggcg gcgtgctgat gtacaagccg cgctcgctgc gcatcgacgc
    10561 ggcgctcgat ggcctgctcg ctgcggtctt tggcgacggc ccggatcggg tgcgtgtgcc
    10621 gcgtgtggtt gatcgcggca gccatggctg ggccgcgttt gccgcgcacc gtcattgcgc
    10681 cgatgacgaa gaactgcgtg cctactaccg cggtcttggc cattggctgg cgatcctgcg
    10741 cctggtcggt ggtaccgaca tccatctgga gaacctgatc gctgtcgggc cggtgccggt
    10801 cgtgatcgat gcagaaagtg tgttctcgca ggtgatcgac gtcgagccgt cgggcctggg
    10861 tgacgcctac gacacggcca tcaagctgat gcgcaattcc gtactgcgca ccggcattgt
    10921 gccgttccgc accaccggcc tcggcatgga aggtgtggac ctgtcggccg ccggcgcatt
    10981 gccgggcgag cagccgcggg tacaggtgcc ggtgatcgtc gaggatggga cggggccggc
    11041 ccggctgggc atggtcgagg ccgaagtcgc catcgcacag aaccacccca gtccacagcc
    11101 ggacgtttcg ttgtactggg accacatcag cgagggcttc atcgacgcca gtcggcgcct
    11161 gcgcgcgctc gatgcgaagg gcgagctgat gccactcctg gcggctttcg agggctgcca
    11221 ggtgcgggat gtgcggcggc cgacaatggc ctacgccgag ctcgggcgga tgctctggca
    11281 tccagcatcg ctgcacaagg aagcccaggc ggttgaacgc gcgatcgatc tgctggtgcg
    11341 caatgcagcg gtgtcaccgg ctgcgccatc ggacctggaa accgtacgtg gagaagtgga
    11401 cgacctgcgc cacggtgaca ttccgatctt cacttcgcag ctggacgcga cccgcatccg
    11461 ctccatcgcc gacaactggc gtgcgatgcg catcgacctc gaagacgtga ccatccgcag
    11521 cacgttggtg gccaccgacc tgaaccagca tgcgctggcc cgcgccgagg ctcggtccgg
    11581 ctacagctat gccgcgcagc accctcgcgc ggacgatctg gacctgcgcc gacgaacgct
    11641 tgcggcacgc gcggtggaga atcttctgcg tctggccgtg cacggtgaag atggttcgat
    11701 gacgtggatc acgcccgagg tgacccgcac aggatggacc gtccagccgg tgcagcccga
    11761 cctgtatttc gggctgggag gcattgcgtt cgcactggcg gcctaccgcc gggaagtgga
    11821 gcagggccgc gccgatccgg tggctgggct ggatccggcc atcgaaggcg ccattgcggt
    11881 gttccagacc atgtgcgagc gccatcccgc agggatcgat ggtggattcg tcggcacggg
    11941 ctcgcagatc tggaccctgc tggcattgca tgatctgctg cagcgccccg cactgctcgc
    12001 gctggccgag cgctgtgcgg aaggagtgga acgtcgtggt ttccaggggc cggtgaagtt
    12061 cgaactgatt gatggcgtgt ccggcatgat cctgccgttg ctggcgctgg ccggggctac
    12121 cggaaacgcg cgctggctgg agctggcggc cgcggccggg cgccgcatgc aggaagcggc
    12181 gatcgtcgat gccgacggcg cacgctggcc gacgccacag ttccgcgagc caatcggtgg
    12241 ctttggccac ggcgcgatgg gcatgggctg ggcgctggca cggctggcgc gttcggatgc
    12301 cggcagcgtg cctgagcgcg ccgcttggcg gcagttggcc gaaggagcgt ttgcgttcca
    12361 ggcggcgctg ttcgaaccgc ataccgggca ctggcgtgac atccacctgc aggatgggca
    12421 gaagaacttc ccgacctggt gccatggcag tgttggcatc ggtctggcgg ccgcggatct
    12481 gtatgcccgc accggcgatc ccgcacagtt gcgtgacatg cggcgggctg tggccgacgc
    12541 gcgtggcaaa tgggggttca gccacaccct gtgccacggc gatgtatcca cccgggagct
    12601 gctggtgctg gcggctgcgc tggatccgga gggatgtccc tatccgcagg atgaggccgc
    12661 catcgagatc gtttcttcga tcgaggagca ccagggcatg gtcggcggac tgacccgcgc
    12721 ggcctttact ccgggcctga tgatcggcct ggcaggtgcg atctatggct tcctgcgcat
    12781 gcatccggcc tgcgcgctgc cgtcgccgtt gctgcaggag acggcggcgg cgcgggtcga
    12841 tgccccggca tcgcgttcca gtgccgcgca ggaccgaccg gcgctggccg aggtctgagc
    12901 cggacgggtc cggtcgcgat cagcggctgg gatcgcgttc cgggcttggc cgctttgcca
    12961 gcttgcgctg cagcgaacga cggtgcatgc cgagcaggcg cgcggccgcg gacacgttgc
    13021 cgccggtctc gtgcatcgcc tgctggatgt gttcccactg caggcggctg atcggcgtca
    13081 tcgcgtccgg cacttccatt tcgccatcgt cggccgggcc gtcgtcttcc tcgccgaggg
    13141 cgcgcaggat catcggcacc gtggccggct tcggcaggta gtcgtcggcg ccgagcttga
    13201 tcgcctccac ggcggtggcg atgctggcgt agccggtcac cagcaggatg cgcatgtccg
    13261 cgcgcagcgc gcgcagcggt tggatcagcg ccaggccgga atcgctgccc agcttcaggt
    13321 cgatcagcgc gaacgccggc ggatgctggc gggccagtgc cagtgcactg gcagcatcct
    13381 gtgcggtctg cgtttcaagc cccttgcggg caaggctgcg ctgcagggta cgcaggtaca
    13441 gctcgtcgtc gtcgaccagc aggccgaggg tggagtggtg aaggctcatg gggtgtcctc
    13501 gcgtggggcc agcggcaggc ggaagccgac gcggctgccg gccccctggg ccgggcgcat
    13561 ccacatctcg ccgtcgaggc gttcgatggt ggcatgggac agggccaggc cgacgcccat
    13621 gccctcgctt ttgctgctgc cgaacagctt gcccggcagc accgcggcac gcgcgtcgaa
    13681 gccgtggccg tagtcgcgga cttcgccgat caggtcgtcg ccttcgatac gcaggtccag
    13741 gtcaacgcgc ggccggccgg cctgttcgcc ggcatcggcg gcattgttga gcaggaccat
    13801 cagcagatgg cccacgcccg ggtcgagtgg cagccgcagc ggcgcatcgt cgttgcggtg
    13861 caggtcgatg gtcggccgca ccagacgcca ttgctccagc acctgctggg cgctggagtg
    13921 gctgcgcccc ggcgcatcgg ccgaagccgg tgcggccagt gcaagcacgc gctcgcggca
    13981 ctgcaccagc agctcgcgca gggtttccat gtcctcgcgc acttccggct cttcgctgcg
    14041 ctcggcgacg tcatcggcga gcagggtcat ggtcgccagc ggcgtattca gttcatgcgc
    14101 caccgaggcg gcatgggtgg ccagggcgac gatgccctcg ttgcgggcga agcgttcgcg
    14161 cagggccgac agttcaagtt cgcgctggcg cagcgccagt gccaggcggg tggagaaggt
    14221 cagcacgacc gctgcggaaa tcaggaaatt ggcgaccacg ccccagcggt tgaggtcctg
    14281 ggcgcggaaa tagccatccg gcagcgactg gccgaagatg ccgctggcgg cgtagccgag
    14341 caggcaggcc agcgcgaccg ccagtgccca gcgcaggggc agggcgaacg cggcgagcgc
    14401 gatcaggatc aggaacagcg aactgaacgg gttggccatg ccgccgctcc agcccaccat
    14461 ccaggtcagg atgatcacgt ccaccaggat gtggccgaac gcggtcagtg gcgcggtgtc
    14521 ggccgcctcc gggcgcagct gggtgtagat gttgaacagg gtcagcacgg ccacgcccgc
    14581 ccacaacggc agctgcggca acggcaggcc cagcacccag gtggcaacca ggatggtggc
    14641 ggcctggcca cctacggcaa gccagcgcag gctgcacagg gtttggagaa acggggcgtc
    14701 gggaccggtc attcacgctc atcgtatgcg ttcacgcgtg cacatgcctg cgacaatcgg
    14761 ccgcagccgt gccgccggct gaatgcgagt cacccggaat gcggaggcgg gcggtagaat
    14821 gcgcccatgc acgacgccgt tacccgcccg acgccccctt ccgatgccac tgcctggccc
    14881 cgccgccaga cccatgccgt ccagatcggc ggggtcaccg taggcggagg caagccggtc
    14941 gtggtgcagt cgatgaccaa cactgacacg tccgacgtgg cctccagcgt gaagcaggtg
    15001 gccgagttgt ggcgtgcggg ttcggaaatg gtgcggctga ccgtcaacac cgtggaagcc
    15061 gctgcggcga tcccgcgcat tgtcgacaag ctggcgatga tgggcattga cgtgccgctg
    15121 atcggtgact tccattacaa cggccatcag ctgctgaccg ccgaaccggc gtgtgccgaa
    15181 gcgctggcca agtaccgcat caacccgggc aacgtcggct tcggcaagaa gaaggacctg
    15241 cagttcgccc agttgatcga gttcgcgatc cgctacaaca agccggtgcg catcggcgcc
    15301 aactggggct cgctggacca ggccctggcg gcgaagctga tggacgagaa caacctgcgt
    15361 gagcagccct gggacgccgg ccgcgtgctg cgcgaggcgc tgatccgctc ggcgctggat
    15421 tcggccgaac aggcggtgga gctcggcctg ccgcgcgacc gcatcgtgct gtcggccaag
    15481 gtcagtggcg tgcaggagct gatcgcggtg taccgcgacc tggcccagcg ctcggatttc
    15541 gccctgcacc tgggcctgac cgaggccggt atcggcagca agggcatcgt cgcttcgtcc
    15601 gcggcgctga gtgtgctgct gcaggaaggc atcggtgaca ccatccgcat ctcgctgacg
    15661 ccggaaccgg gccagtcgcg tacgcaggaa gtgatcgtcg cccaggaact gctgcagacc
    15721 accggccagc gtgccttcac cccgcttgtc acagcctgcc cgggctgcgg ccgcactacc
    15781 tccgagttct tccaggagct ggccaaggtg gtgcagaacc acgtgcgcga gaagatgccg
    15841 ctgtggaaga tccaccaccc gggtgcggag aacatgaccc tggcggtgat gggctgcatc
    15901 gtcaacgggc cgggtgagtc gcgccatgcc aacatcggca tctcgctgcc gggcaccggt
    15961 gaaaccccgg ctgcgcccgt gttcgtcgat ggcgagaaga aggtgaccct gcgtggcgac
    16021 aacatcgccc aggaattcgt cgccctgatc gacgattacg tcgaacacaa gtatgtccga
    16081 agcgccggat aagcctgcga tcctcgctgc accggagtcc gcctccggct tccgccactg
    16141 gatggcgcgc aacgcctggc gcctggtcct gttgttcggt ggcgtactgc tgccgctggc
    16201 aggttttgtc gccctggcgg acgaagtgca cgagtttgaa tcgttccatt tcgatgcgcc
    16261 cctgctgtgg cagatgcatg gcctgcattc gccgtggctg gaccgcttct tcgtgctcat
    16321 ctcgaaactg ggctacgagt ggttcctgat cccggccgac gtgctgatca tcggcgtgct
    16381 gctgggctac cggcgttggc gtgaggccac cttcgtggcg gtcagcttcg tcggctcggc
    16441 gctgctgaac atgggcagca agcacttctt ccagcgccag cggccgagcc tgtgggaatc
    16501 gatcgcgccg gaatcgacgt tcagcttccc cagcggccat gcgatgggct cgatgaccct
    16561 ggcggtgacc ctggtactgc tggcctggaa cacccgctgg cgctggccgg tgctgctgct
    16621 ggcaccggca ttcagcctgc tggtcagcgt gtcccgggtc tacctggggg tgcattaccc
    16681 ctccgatatc ctggccggat ggtgtgccgc gctggtttgg gtggtagggt gctatctggt
    16741 catgttcagt cgccggcacc catggcgacg tcacggctcg ccgccagcga aggccagcga
    16801 agcatcatca cagggggttt gacgtggatg gcccttgagg gacgtctacg tgatagatca
    16861 gttgtttcgt tgcagcaggt tctgcaagac agggggcaag cacaacgcgc cgtactgtga
    16921 tgcgcaaggc agatcgccgc cgccgcattc cagacgcgct tgcagggtat cggcaccctg
    16981 cctagcttga cctgcaatgg ccgcattcga agaggtacgt gaatgacgat tcgagtctac
    17041 ttggtggatg accacgcgct ggtccgcacc gggatgaaga tgattctgtc gggggaaacc
    17101 gacatcgagg tggtgggcga agccgagacc ggcgaagacg cgctgcgtga agtccgtcag
    17161 ctgctgccgg atgtggtgct gtgtgacctg cacctgccgg gtgtgagtgg catggaagtg
    17221 accgagcgca tcgtgcgcag ccaccgcaat acccgcgtgg tgatcgtgtc ggtgctggaa
    17281 gatggcccgc tgccgaagcg gctgctcgag gctggcgccg ccggttacat cggcaagggc
    17341 tgcgatgcgc aggagctgtt gcgcgcggtg cgtgacgtgg ccggtggccg tcgttacctg
    17401 ggcaccagca tcgcgcagaa tctggcgctg tcgacggtgg aaggcaacgg ttcgccgttc
    17461 gacagcctgt cgccgcgcga gctggaggtg gcgttgctgc tgacccaggg cctgcgccag
    17521 gaagacatcg cgcggcggtt gagcctgagt gcgaagacgg tgaacacgca caaggcacgg
    17581 ttgttcgaga agatgggaat ccacgacaac atcgcattgg cgcggatggc cagccagtac
    17641 gggctggtgg atccggcacg gccgttgtga gggattccgc caacggctga gcccctcgcg
    17701 gtggagtgcg gttggattct gggggatggc cgggcggatg ggctgtgcag ggggcgctgc
    17761 aagtacgtcc atgtgagctc ggtcgccgca tccatgcggc tcacgcccct gcacaaccca
    17821 tccgcccggc cacggacagg ttccgtgcgc gtccaccgcg gaaagaagaa gggaaaagcg
    17881 agagcgggtc gcgcgctgcg cgcgctctgg atgatggttc tgtagagccg agcccatgct
    17941 cggctgcttt ccgttccgct ggcgcggagc cgagcgtggg ctcggctcta cacccgcgtc
    18001 ggctcagtgg ccgcgcacgc gcttgatgat cttggcggcg tctgcggcgc tggcgcgcac
    18061 cttgtcccat tcgccgttgg cgatccagtt gcccggcacc atccacgaac cgccgatgca
    18121 gaccacgttc ttctgctcga ggtattcggc ggcggtgttt tcggtgatgc caccggtcgg
    18181 gcacagctta aggtccgcca ccgggccggc caggcccttg atcatcgcca gcccacccac
    18241 ggcggtggcc gggaacagct tgcacacacg gaagccccgc gcatacagcg acagcagctc
    18301 ggtcggcgtc gccgcacccg gtaccaccgg cagcggcgca gcggccagtg catcggcaag
    18361 cgccggtggc gtacctgggg tcaccagaaa gtccgcgccc gcatcgatcg actgctgcat
    18421 ctgctccacg gtcagcaccg taccggcacc caccaccaca tccggcagct cgcgcttgag
    18481 catcgccagc gcttccatcg ccaccggcgt acgcagcgtc agctcgatcg ccggcaggcc
    18541 accttccagc agcgccgcac tgaccgcacg cgcctggtcc agcgtatgaa tcgtcaccac
    18601 cggcaggatg cccgccgcac gcaacagctc cgccgccttc acctgatgtt gttcgatacc
    18661 catgcttttg cccttgcctt tgctcttctt gattcagtgg ccgcagcgca aatgacgcgc
    18721 cgggaattgt ccaagggcag tagagcgccc tggccgggac cgtgagcggc atggatgccg
    18781 cgatcgagcc cccatggatg ggtttacggc gtgtcccggg cagggcgctc tactgcccaa
    18841 gccgggaagc ctgccgcggg ttttcgcttc aggcgtcttt cgcctcatgc ggcgccgccg
    18901 ccgccgcggc atcgtgcccc agctcatact ccgcatcgta atcccacggc ccaccatcag
    18961 ccgccgccgg cccgcacgaa atcgaaatcg caccctggtc ggccgggccc accacgcggc
    19021 ggttgatcgc gaacaggtta cggcccaggt catgcgcggc aggcgcagtg ttcggcgcca
    19081 gcgggcgcgc agcccattcg gctgcgtcca ccagcacttc cagcgtgccg gcctcgccat
    19141 ccaggcggat catgtcgccc tcgcggacct tggccagcgg gccgccgcgc gccgcttccg
    19201 gcgtcacgtg gatcgctgcc ggaatcttgc ccgaggcgcc ggacaggcga ccgtcggtga
    19261 ccagcgccac gcgccggccc tggttctgca gcagacccag cagcggcgcc agcgaatgca
    19321 gttcgggcat gccgttcgca cgtggaccct ggtatcgcac caccgccacg aaatgctccg
    19381 gcagcaggcc accggcgtgc agcttgttca acacctgcgg tgcatcgacc accacggccg
    19441 gcgcttcgat cgtgcggtac tgcggcttca ccgccgacag cttgatcagc gacttgccga
    19501 ggttgccgcg cagcaggcgc aggccaccct ggtgctcgaa cggattgtcg acgccacgca
    19561 cgacctcttc gtcggcgctg cgttccaggc ccggcagata aaccagctgg ccatcgcgca
    19621 gctgcggttc acgggcgtag tcggccatgc cgccgcgcgc cacgctgacc aggtcgccgt
    19681 gcatcaggcc ggccttgatc agctcgccga acacgaacgc cgggccaccg gcagcggcga
    19741 agcggttcac gtcggcgtcg ccgttcggat agacgcgggc cagcagcgga atcagctgcg
    19801 acagttcgtc gaagtcgtcc caggtcagca cgatgccagc cgcacgtgcc accgcgatcc
    19861 agtggatggt gtggttggtc gaaccgccgg tggccatcag cgcgatgact gcgttgatga
    19921 tcgcgcgctc gtcgatgatc cggcccagcg ggcggaagtc gtcgccgagc gcggtgatgt
    19981 ccagtgcacg ttcggtggct tcgcgggtca gcgcatctcg cagcggcgtg cccggattga
    20041 cgaacgacgc gcccggcagc tgcacgccca tcgcttccag cagcacctgg ttggaattgg
    20101 cggtgccgta gaaggtgcag gtaccggcgc cgtggtacga ggcagactcg gcttccagca
    20161 gttcttcgcg ggtggcttcg ccggcggcgt agcgctcgcg cacttcagcc ttctgcttgt
    20221 tcgggatgcc cggggtcatc gggccggccg gcacgaacac cgccggcaga tgaccgaacg
    20281 ccagcgcacc gatcagcagg cccggtacga tcttgtcgca gacaccgagg tagacggtgg
    20341 tatcgaacat gtcatggctg aggccgatgg ccgtggcctg ggcaatgaca tcgcgcgaga
    20401 acagcgacag ctccatgcca ccacggccct gggtgacgcc gtcgcacatc gccggcacgc
    20461 cgccggccac ctgtgccgta gcaccgagct cgcgggcgat gtcgcggatc tgctccggat
    20521 aggtctcgaa cggctggtgc gccgacagca tgtcgttgta ggcggtgatg atgccgaggt
    20581 tcggcgtcac gccgccgcgc aggcggctct tgtcggtgcc gccgcaggcg gcgaacccgt
    20641 gggcgaggtt gccgcagctc aggcggctgc ggaacgggcc ctcacgcagg gaggcgtcga
    20701 tcgcggccag ataggcggca cgcgaggcgg cgctgcggcg gatgacacgc tcagtgatgg
    20761 cttgcagttg cggatggagg ctcattggct accggcgttc gtggtggcga gaggcaagcg
    20821 gcggcgcggc gccgccgccg acatcaatca gcccagtgga cgcgcaggcg cgcgccttcc
    20881 aggttgatcg cgttgaggat cgggtactgc tgggcgtcgt tgctgtccag cgcctggcgc
    20941 agtacctgca gcttctgctt gccacgcagc agcagcaggc gctggcggca ctggcgcagg
    21001 ccgtgcgggg tcagcgtgat gcgcagcggc cactggttcg cgcccgggca gccggtggca
    21061 tccagtgccg cgtagggcag ggtgctttcc agtgcacggg ccaggtcttt cgagcccggg
    21121 aacagcgagg cggtgtggcc gtcgttgccc atgcccagtg ccaccaggct cggcggctgg
    21181 ctgtgctggg cctgcaggtt ggcggtgtaa acgcattccg gcagcggctt gccgacgcgc
    21241 accagcggat cgaaatgcgc accttcggcg cgcttgagca ggtgttcgcg caccagccag
    21301 gcattgctgt cgcgatcctg cggcgacagc cagcgctcgt cggccaggct cacttccacc
    21361 cggtcccagt gcacgtccaa ctcggccagc gcctggtaga ccggcgccgg cgtggtgccg
    21421 ccggacaaca ggatgcgggc gcggcccact tcgttgatgt cgtggttgag ggtctgcgcc
    21481 atctcggcgg ccaccgcctc gatccagcca tcggcatcgc cgtggttgat gaattcgatg
    21541 cggtcgtcgt ggaaggtggg gctcatgcgg caactcctgg tgcgtcacgt tcggcgtcgg
    21601 cggcataggc ggcggcgccc agcaatccgg cgtggggatg catcaccgcc aacgaaggaa
    21661 cccgcgccat gatcgaagag aaccgtccct tgtgttcgaa gcgctggcgg aaaccggagt
    21721 gctgcagcga atcgagcatc ttcggggtca ggccgccggt caggaacacg ccgtcccagg
    21781 caccctgggt cagcaccagg tcaccggcaa tggcgccaaa caccgcgcag aacacatcca
    21841 cggtgcgcat tgcctgcgga tcaccgtgca gggcgcgggc ggtcacgtcc accggctgca
    21901 gctggccggg atcgatgccg gccatctcgc acaccgcgcg gtggatgttg accagcccgg
    21961 ggccacagat caggcgctca ttggagacgc ggccgaactg ctcggacagg atctccagga
    22021 tgcggatctc ctccggcgtt cccggcggga agctgacatg gccgccttcg gtttccagcg
    22081 ggtagcagcg gccgtggcgc aggatcaggc caccgacacc caggcccgta cccggcccga
    22141 tcaccgcgta gttgcgcggc tggccgggct tgcccgggac ccaggcggca ccgccgacct
    22201 ggaccacgtc atcgggctgc agcagcgaaa tcgccatcgc ctgtgcggcg aagtcgttga
    22261 tcaggtgcag ctcgtcgaaa ccgagcatgg cggcggtgcg gctgcgcgag atcacccacg
    22321 gatggttggt gatgcgcgct tcgtcaccgt cgacgcgacc ggccactgcg aacacgccgc
    22381 ggctggccgt ggcgccgatc tgttccagat ggtggcgcgc ggcatcaccc agcgacggga
    22441 actccgccac cgcgtactca cggatgctgt ccttctgcag tggcgcgtcc tgggaggtgt
    22501 cggccagggc gaagcgggcg ttggtgccac cgatgtcggc gaccagcacc ggctgcgagc
    22561 tggcactcat gccgacgctc cgctgtccgg cgcatccacg ccctgcggca ggaactcgcc
    22621 cgcgttggcc ggaccccact ggccagcggg gtagggctcc agcggcagct tggcgtcctt
    22681 ccacgcgtcg gcgacgctgt cgatccacgc ccaggcggca cgcacttcgt cgtcgcgcac
    22741 gaacagcgtg tggttgccgt tgaaggcatc caggaacagg cgttcgtagg cgatgcggcg
    22801 gtgcaggccg gtcggcaccg acagttccag ttccagcggg tgcagttcca gcgcgcccca
    22861 ttccgggccg gccaggctgc tcatcaggcc cagttcga
//
