LOCUS       NZ_CP090418            10846 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Stenotrophomonas maltophilia strain WGB211 chromosome, complete
            genome.
ACCESSION   NZ_CP090418
VERSION     NZ_CP090418.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas maltophilia
  ORGANISM  Stenotrophomonas maltophilia
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas; Stenotrophomonas maltophilia
            group.
REFERENCE   1  (bases 1 to 4913676)
  AUTHORS   Ma,Y.
  TITLE     Complete genome sequence analysis of long-chain alkane degrading
            bacterium Stenotrophomonas maltophilia WGB211
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4913676)
  AUTHORS   Ma,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-DEC-2021) College of Life Science, Northwest
            University, No. 229 Taibai Road, Xian, Shaanxi 710069, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.2
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 344.0x
            Sequencing Technology             :: Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021441865.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 14:29:32
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,549
            CDSs (total)                      :: 4,458
            Genes (coding)                    :: 4,408
            CDSs (with protein)               :: 4,408
            Genes (RNA)                       :: 91
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 74
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 50
            CDSs (without protein)            :: 50
            Pseudo Genes (ambiguous residues) :: 0 of 50
            Pseudo Genes (frameshifted)       :: 25 of 50
            Pseudo Genes (incomplete)         :: 28 of 50
            Pseudo Genes (internal stop)      :: 6 of 50
            Pseudo Genes (multiple problems)  :: 7 of 50
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:49:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1227617
            Orig. end                         :: 1238463
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP090418.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from School of Life Sciences,
            Northwestern University, China.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10846
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10846
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5846](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            268..1809
                     /locus_tag="LYZ64_RS05850"
     CDS             268..1809
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479412.1"
                     /locus_tag="LYZ64_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TerC family protein"
                     /protein_id="WP_164089334.1"
                     /transl_table=11
                     /translation="MEWLADPSIWMGLATLVVLEIVLGIDNLVFIAILADKLPPHQRDR
                     ARVIGLALALLMRLVLLAALAWIMKLTEPLLTLFDHSFSGRDLILLGGGLFLLFKGTME
                     LHERLEGREHHEDGKKVYASFAMVVAQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTI
                     AMALMLVASKPLTRFVNKHPTVVVLCLGFLLMIGFSLVAEGLGYKIPKGYLYAAIAFSI
                     LVEAFNQWVRFNRERNERRQPFRQRTADAVLRMLGARPANGHDDEGVDEQVDAEERLQP
                     AEHEMIRSVLGLADRPVSSVMTVRADVQWIDLARGQEDVVARLVASPHTRLLVGDGDLD
                     SLRGVVQSRDLLADLLQGKPLQLEDNLREPQYVLSSASALQALELIRQHPVPLAVAVDE
                     YGSVEGLVTANDLLAAIAGDLVDTQDERYGVVAQGEDCWEADGALTLDDLQRLAGVSLP
                     RSADYMTISGLVLEQLGRLPDVGDAVEVTGVRVTVLAMEKRRIARLRVERLGAAP"
     gene            1932..3068
                     /locus_tag="LYZ64_RS05855"
     CDS             1932..3068
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004147841.1"
                     /locus_tag="LYZ64_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_164089335.1"
                     /sec_met_domain="Metallophos_2 (E-value: 1.3e-08, bitscore:
                     33.1, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVAVLSTIGLLMGLYVAWRLFWPLRMRIWMKVVLSLLLVGVAVQL
                     RIVAMFWGTMASPEIPKLAIATLATGSTAVLLLALVMLMLDAGLLLSHLLRWPRTVSAL
                     RTPKLRPMAGLLALLVSGYGVSQGMAVPKPRQIEVSIAGLPAAFDGYRVLQLTDIHASR
                     LLTGDWVRKVVDESNALTPDLIVITGDLIDGSVEARRDDARPLADLHAPDGVIAITGNH
                     EYYAQYQAWMQAFRALHMQVLENSHLQVRRGDAALTIAGVTDPVAARYGLPLPDLGAAL
                     AGADPTAPVILLDHRPRNAREAAARGVKLQLSGHTHGGQIIGMDQLVQRANGGYVSGRY
                     DVDGMTLYVSNGAGLWAGFPARIGVPSEITLVTLRRVP"
     gene            complement(3081..3485)
                     /locus_tag="LYZ64_RS05860"
     CDS             complement(3081..3485)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LYZ64_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164089336.1"
                     /transl_table=11
                     /translation="MLLRPHGYPLHALQQRLPHVSGPEEIRPHFKEGQRDIQRIRVMFG
                     QPFQRVGIAARKRQTRVVLVEFCTGRNVPLPLLRPTPARARGIADHLAEPVDLIGIGSD
                     QAFHRGAGMGHGSFHMICQGSDPFPQGKGI"
     misc_feature    3549..3561
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            complement(3582..4220)
                     /locus_tag="LYZ64_RS05865"
     CDS             complement(3582..4220)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408497.1"
                     /locus_tag="LYZ64_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_164089337.1"
                     /transl_table=11
                     /translation="MTVSNTSFLHGWRLFVAISVVLIAFALTAFALHPDAAEGSRAAIR
                     VTARTSFLLFLTVFTASSFASLLPGPFTRFLLRERRIIGLSFAFSHLLHAIAITSFGIL
                     NPAFWPARSALTNLPGTVGYIAILALAITSHRGLARRIGPTAWRRLHVTGMWIIAAVFT
                     YSYFKRVPGNFWYAVPSALLFTAFVVRWIAKRVQALRRCTHARPPLRAA"
     gene            complement(4223..5008)
                     /locus_tag="LYZ64_RS05870"
     CDS             complement(4223..5008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659351.1"
                     /locus_tag="LYZ64_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_164089338.1"
                     /transl_table=11
                     /translation="MAESLATLQRRWADHVRDPSIAAPDGIEARRLAVYRRLCIDSLDT
                     LLAGTLPRLQHQLGTPRWRDTVEHYYASHTCRTPLFPQIAGEFAAWLAMQDALALPAWA
                     AELAHYESTQQSLHIEARVAGRLLHRIPVDSDVLAVSPLVRVLGYRWPVHVDEMLEPMP
                     DAAPTLLLMRRMPEFSLRVEELAPLAYAVLLAFGDDGTRVDDVLQTVAEAHGVAPDELR
                     AACIPVLRDLCAAAVLVASTDPRERRPAAGTTPSPFFEA"
     gene            complement(5001..5846)
                     /locus_tag="LYZ64_RS05875"
     CDS             complement(5001..5846)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646321.1"
                     /locus_tag="LYZ64_RS05875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_164089339.1"
                     /sec_met_domain="DUF692 (E-value: 4e-119, bitscore: 394.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPLPSNAAGLGLRRGLIDELLAMPAGAIDFLEVAPDNWIGVGG
                     AHGAALCRLSERHPLTCHGLSLSLGGPDPLDRTLLAQTRDFLDLHQVRLYSEHLSYCAA
                     GGHVYDLLPLPFTAEAVHHVAGRIAQVQDMLGRRIAVENISYYAVPGADMSEIDFINAV
                     LTEADCDLLLDVNNVFVNACNNGYDAFEFLARVPSHRVASLHVAGHFDEDDGFKIDTHG
                     APVKGVVWALLREAYARVGVRPTLLERDFNFPPLAELLAEVAQIRQAQVEARWPEVAHG
                     "
     gene            complement(5903..6379)
                     /locus_tag="LYZ64_RS05880"
     CDS             complement(5903..6379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412584.1"
                     /locus_tag="LYZ64_RS05880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_164089340.1"
                     /transl_table=11
                     /translation="MSVSTKNTPSSRLPRVGAIGIALAGGLLLAGQAAAIQPLAISAVA
                     MSAAAEGKCGEGKCGASKATTGKPAGKARVAEGQCGEGKCGDASFARTDRDHDGKVSRA
                     EFNAVAAKRAAEFDRIDTDHDGYITEQEAHDYLRSVYTANGKPMPKGLFSRVAD"
     gene            complement(6472..7116)
                     /locus_tag="LYZ64_RS05885"
     CDS             complement(6472..7116)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="LYZ64_RS05885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_164089341.1"
                     /transl_table=11
                     /translation="MISTASSVYTPRLDAVGRWLSPVALRILLAWEFFESGREKLGGQN
                     WFADLEGRFPFPFSTLPASLNWQLATWLELVGAVMLLLGLATRAVAYVFWVLTVVAIAA
                     VHWPDQWNGLGELWQGYAITDQGYGNFKLPLLFLAMLLPLILNGGGALSVDRLLAGSPH
                     APAGNDGLGWGVSLIALLLPVAALLPGIGFGGALLGGVLLLGHLLRRRRSA"
     gene            7459..8253
                     /locus_tag="LYZ64_RS05890"
     CDS             7459..8253
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408502.1"
                     /locus_tag="LYZ64_RS05890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_164089342.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.1e-15, bitscore:
                     54.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRSSLLAAALALAGAAAPAFATQADTAAPPTVILVHGAFADGSS
                     WSKVIRTLHDWKLPAVAVQNPLTSLADDVAATRRAIAAAPGKVVLVGHSWGGTVITEAG
                     DDPKVQALVYVAAFAPDAGQSSAQQGEGFPVGPGLARLQERDGYLTLPADAIAQDFAPD
                     VMKKSAALLYSTQVPLKASALGEVVNVAAWRSKPSWYVLSRDDRMLSPQLQAATARRIG
                     AQLQSIGSSHVSLLSHPAQVADSILEAAGVKPAELPLAEQGG"
     gene            8257..8802
                     /locus_tag="LYZ64_RS05895"
     CDS             8257..8802
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415663.1"
                     /locus_tag="LYZ64_RS05895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="redoxin family protein"
                     /protein_id="WP_164089343.1"
                     /transl_table=11
                     /translation="MAALRGYALPLLLGLLGGAALLLAWPGAEAGAQPLDAAPKAGFGG
                     GGPWHNSPPMTLKQLRGQVVLVEFWTYTCSNCLNVAPYVHQWHARYASQGLQVIGVHTP
                     EFAYEGLPGNVSRAITRLDITWPVVQDNQYRIWNAWGNRFWPALYLLDRQGRVVYRHYG
                     EGDYARTESEIQRLLASP"
     gene            8860..9600
                     /locus_tag="LYZ64_RS05900"
     CDS             8860..9600
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659345.1"
                     /locus_tag="LYZ64_RS05900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_100471599.1"
                     /transl_table=11
                     /translation="MNPVPHILVVDDDSEIRQMLADYLQRNGLRVSQADGGRAMRALMD
                     THAVDLVVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYV
                     TKPFSSRELLARINAVIRRTQMLPPNLQVSEAGRQLAFGAWRLDTTARHLLDAQDTAYP
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLLVSRVRQRLGDDAREP
                     TYIKTVRSEGYVFSVPVQLLGPDE"
     misc_feature    complement(10396..10410)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 tggcgatcgt catcaccctg gaccgcatgc tgcaggaacg gggcatgacc ctgtccgagc
       61 tggccgggcg catcgacatc accctggcga acctgtcgat cctgaagacc ggcaaggcgc
      121 gcgccatccg cttttccacg cttgatgcga tctgccgcga gctgcagtgc acgcccggcg
      181 acttgctcgg gtatgacccg gcgcaggcgc aggacgccga ttgaatgact gctcttttcc
      241 cttgcctact gacgaaacgg acctgaaatg gaatggttgg ctgacccctc gatatggatg
      301 ggccttgcaa ccctggtcgt gctggagatc gttctcggca tcgacaacct ggtgttcatc
      361 gcgatccttg ccgacaaact gccgccgcac cagcgtgacc gcgcgcgggt gatcggcctg
      421 gcgctggccc tgctgatgcg gctggtgctg ctggccgcgc tggcctggat catgaaactg
      481 accgagccgc tgctgacgct gttcgaccac agcttctctg ggcgtgacct gatcctgctg
      541 ggcggtggcc tgttcctgct gttcaagggc accatggagc tgcacgaacg gctggaaggc
      601 cgcgagcacc acgaggatgg caagaaggtc tatgccagct tcgcgatggt ggtggcacag
      661 atcgtggtgc tcgacgcagt gttctcgctg gactcggtga tcaccgcggt tggcatggtc
      721 gacaacctgg gcgtgatgta cgccgcagtg accattgcga tggcgctgat gctggtggcc
      781 agcaagccgc tgacccgctt cgtcaacaag catcccacgg tggtcgtgct gtgcctgggc
      841 ttcctgttga tgatcggttt cagcctggtg gccgaaggcc tgggctacaa gattccgaag
      901 ggttatctgt acgcggcgat cgccttctcg atcctggtcg aagcgttcaa ccagtgggtg
      961 cgcttcaacc gtgagcgcaa cgagcgccgc cagccgttcc gccagcgcac ggccgatgcc
     1021 gtgttgcgca tgctgggcgc gcgcccggcc aacggccacg acgacgaagg tgtggacgag
     1081 caggtagacg ccgaagagcg cctgcagccg gccgaacacg agatgatccg cagcgtgctg
     1141 ggcctggccg atcggccggt gtcgagcgtg atgaccgtgc gtgccgacgt gcagtggatc
     1201 gacctggcac gtgggcagga ggacgtggtg gcgcgcctgg tggcatcgcc gcatacccgc
     1261 ctgctggtcg gcgacggtga tctggacagc ctgcgcggcg tggtgcagag ccgcgacctg
     1321 ctggccgatc tgctgcaggg caagccacta cagctggaag acaatctgcg tgagccgcag
     1381 tacgtgctgt ccagtgccag cgcattgcag gcgctggaac tgatccgcca acacccggtg
     1441 ccgctggcgg tggcggtgga cgagtacggc agcgtggaag gcctggtgac cgccaacgac
     1501 ctgctggcgg ccattgccgg tgacctggtc gacacccagg acgaacgcta tggcgtggtc
     1561 gcgcagggcg aagattgctg ggaggccgat ggcgcgctga ctctggacga cctgcagcgc
     1621 ctggccggcg tctcgctgcc gcgcagtgcc gactacatga ccatctccgg tctggtgctg
     1681 gagcagctgg gccgcctgcc ggacgtcggc gatgcggtgg aggtgaccgg tgtacgcgtc
     1741 accgtgctgg caatggagaa acgccgcatc gcccgcctgc gggttgaacg cctgggcgcg
     1801 gcgccatagc cgccgcgtcc cctgtagagc cgagcccatg ctcggctgca ttttgagaag
     1861 ccgagcgcag gctcggctct acacaacacc tcccgcaacc gtcaccatgg cgggcccgtt
     1921 ttccttcccg gatggttgca gtgctgagta cgatcggttt gttgatgggc ctgtatgtgg
     1981 cctggcgcct gttctggcca ctgcgcatgc gcatctggat gaaggtcgtg ctgtcgctgc
     2041 tgctggtggg cgttgccgtg cagctgcgca tcgtagccat gttctggggc acgatggcct
     2101 cgccggagat accgaagctg gccatcgcca cgctggccac cggctccacc gccgtgttgc
     2161 tgctggcgct ggtgatgctg atgctggacg ccggcctgct gctgtcgcac ctgctgcgct
     2221 ggccgcgtac tgtatcggcc ctgcgcacgc cgaagctgcg gccgatggca ggtctgctgg
     2281 ccctgctcgt gagtggttat ggtgtcagcc agggtatggc cgtccccaag ccccggcaga
     2341 tcgaggtgag catcgccggc ttgccggccg cgttcgatgg ctatcgcgtg ctgcaactga
     2401 ccgacatcca tgccagccgc ctgctgaccg gcgactgggt gcgcaaagtg gtggatgaga
     2461 gcaacgcact gacgccggac ctgatcgtga tcaccggtga tctgatcgac ggcagcgtcg
     2521 aggcccgccg cgacgacgcg cggccgctgg ccgatctgca tgcaccggac ggcgtcatcg
     2581 ccatcaccgg caaccacgag tactacgcgc agtaccaggc gtggatgcag gcgttccgcg
     2641 cgctgcacat gcaggtgctg gagaacagcc acctgcaggt gcggcgcggt gatgcggcgc
     2701 tgaccatcgc cggcgtcacc gatccggtgg ccgcacgcta cggcctgccg ctgccggacc
     2761 tgggtgccgc gctggccggt gccgatccga cggcacccgt gatcctgctt gatcatcgcc
     2821 cgcgcaatgc acgcgaagcg gccgcgcgtg gcgtgaagct gcaattgtcc gggcataccc
     2881 acggcgggca gatcatcggc atggaccagc tggtgcagcg tgccaacggt ggctatgtct
     2941 ctggtcgcta cgacgtggat ggcatgaccc tgtacgtgag caatggtgca ggcctctggg
     3001 caggttttcc ggcgcgcatc ggcgtaccgt cggagatcac cctggtgacg ctgcgccgcg
     3061 tgccgtgacc tgaagtgggg tcagatccct ttgccttggg gaaagggatc tgacccctga
     3121 caaatcatat ggaaggaacc atgtcccatc cccgcgcccc gatggaacgc ctgatccgag
     3181 ccaatgccga tgagatcaac tggctccgcc aggtgatccg cgataccgcg ggcgcgcgct
     3241 ggcgtgggcc ggaggagcgg gagcggcacg ttgcggcctg tgcagaattc caccagaact
     3301 acgcgcgtct ggcgtttccg ggcggctatg ccaacgcgct gaaacggctg gccgaacatg
     3361 acccgaatac gctggatgtc gcgctgacct tccttgaagt gcggccgtat ttcttccggt
     3421 ccggatacat gtggaagacg ttgctgaagc gcgtgcaacg ggtagccatg gggacgaagc
     3481 aacacgcgcg gctgcaggag atcctcgatg cctacgctgc ctatcgcgcc acacggggtc
     3541 agatcccttc gcctttggca aaggggtctg accccggccc gtcaggccgc ccgcagcggc
     3601 ggccgcgcat gcgtgcatcg gcgcagcgcc tgcacccgct tggcgatcca gcgcaccacg
     3661 aaggcggtga acagcagcgc cgatggcacc gcataccaga agttgcccgg cacgcgcttg
     3721 aagtacgagt aggtgaacac cgccgcgatg atccacatgc cggtcacgtg caggcgacgc
     3781 caggccgtgg gtccgatgcg ccgggcgagc ccccggtgcg aggtgatggc cagcgccagg
     3841 atggcgatgt aacccaccgt gcccgggagg ttggtcagcg ctgagcgtgc tggccagaac
     3901 gccgggttga ggatgccgaa actggtgatg gcgattgcgt gcagcaggtg cgagaacgcg
     3961 aaggacaggc cgatgatgcg ccgttcgcgc agcaggaaac gagtgaacgg gccgggcagc
     4021 aggctggcga acgacgatgc cgtgaacacc gtcaggaaca gcaggaacga tgtgcgtgca
     4081 gtgacccgga tcgccgcccg gctgccttcg gctgcatcgg gatgcagggc gaaggcggtc
     4141 agtgcgaacg cgatcaggac cacgctgatg gctacgaaca ggcgccagcc gtgcaggaag
     4201 gacgtgttgg aaacggtcat ggtcaggcct cgaagaatgg agagggggta gtgccggccg
     4261 ctggccggcg ttcccgggga tcagtcgacg caaccagaac ggctgccgcg cagaggtcgc
     4321 gcagcactgg aatgcaggcc gcacgcagtt catccggcgc gacaccatgt gcttcagcca
     4381 cggtctgcaa tacgtcatcc acacgtgtgc cgtcatcgcc gaaggccaac agcaccgcat
     4441 aggccagcgg ggccagttcc tcgacacgca gactgaattc aggcatgcgg cgcatcagca
     4501 gcagcgtggg agctgcatcc ggcatcggtt ccagcatctc gtccacatgt accggccacc
     4561 ggtagccaag cacccgcacc agcggcgaaa ccgccagcac atcactgtcc accggaatgc
     4621 ggtgcagcaa acgcccggcg acacgggctt caatgtgcag cgactgctgt gtgctctcgt
     4681 agtgcgccag ttccgctgcc caggccggca gtgccagcgc gtcctgcatc gccagccacg
     4741 ctgcgaattc gccggcgatc tgtgggaaca acggggtgcg acaggtgtgg ctggcatagt
     4801 agtgctccac tgtgtcgcgc cagcgcggcg tgcccaactg gtgttgcagg cgtggcaggg
     4861 tgccagccag cagggtgtcc aggctgtcga tgcacaggcg acggtacacc gccagccggc
     4921 gcgcctcgat gccatcgggt gcggctattg atgggtcgcg cacatggtcg gcccagcgcc
     4981 gttgcagggt agccagcgac tcagccatgg gccacctcgg gccaacgtgc ctcgacctgc
     5041 gcctggcgga tctgtgcgac ctcggccagc aactctgcca acggcgggaa gttgaagtcg
     5101 cgttcgagca gcgtggggcg cacgcccacc cgcgcatagg cctcgcgcaa cagcgcccag
     5161 accacacctt tcaccggcgc accgtgggta tcgatcttga agccatcgtc ttcatcgaag
     5221 tggcccgcca cgtgcagcga ggcgacacgg tgggacggca cgcgggccag gaattcgaag
     5281 gcgtcgtaac cgttgttgca ggcgttgacg aagacgttgt tgacgtccag cagcaggtcg
     5341 cagtcggctt cggtgagcac ggcgttgatg aagtcgatct cgctcatgtc cgcgccggga
     5401 acggcgtagt aggagatgtt ctccacggcg atgcgtcggc ccagcatgtc ctgcacctgg
     5461 gcgatgcgac cggcgacatg gtgtacggcc tcggcggtaa acggcagcgg cagcagatcg
     5521 tagacatggc caccggcggc gcagtagctc aggtgttcgc tgtacaaccg cacctggtgc
     5581 aggtcgagga agtcgcgcgt ctgtgccagc agggtgcggt ccagcggatc aggtccgccc
     5641 agcgacagcg acaggccatg gcaggtcagg gggtggcgtt cgctcaacct gcacagcgct
     5701 gcaccgtgtg caccaccgac gccgatccag ttgtcgggcg caacttcgag gaagtcgatg
     5761 gcaccggccg gcatggccag cagttcgtcg atcaggccac ggcgcaggcc aagaccggcg
     5821 gcattggaag gcaggggcag ggacatggcg gatgctccag ggtgagggcg ccgcctcgga
     5881 ggcggcgccg gttgaacgtc gatcaatcgg caacgcggga gaacaggccc ttcggcatcg
     5941 gcttgccgtt ggcggtgtag acgctgcgca ggtagtcgtg cgcttcctgc tcggtgatgt
     6001 agccgtcgtg gtcggtgtcg atgcggtcga actcggcggc acgcttggcg gccacagcgt
     6061 tgaactcggc gcgcgagacc ttgccgtcgt ggtcacgatc ggtgcgggca aacgaggcgt
     6121 cgccgcactt gccttcgccg cactggccct cggccaccct ggccttgccg gcgggcttgc
     6181 cggtggtggc cttgctggcc ccgcacttgc cttcaccgca cttgccttcg gcggcagcgc
     6241 tcatggccac cgcgctgatc gccagcggct ggatcgccgc ggcctggccg gccagcagca
     6301 ggccaccggc cagggcgatg ccgatggcac cgacgcgcgg caggcgggag gagggggtgt
     6361 tcttggtcga gacggacatg tgatgactcc ttgggaaagc acgcggggcg tgcgggatgg
     6421 acgccgccga acaggcgacg gaaagaggtg cgtgggaaaa agcagatcag atcaggcgct
     6481 gcggcgacga cgcagcagat ggcccagcag cagcacaccg ccgagcaggg caccgccgaa
     6541 gccgatgccg ggcagcagcg cggcaaccgg cagcagcagg gcgatcaggc tgacgcccca
     6601 gcccaggccg tcgttgccgg cgggggcatg cggcgagccg gccagcagcc ggtcgacgct
     6661 gagtgcgcca ccaccgttga ggatcagcgg cagcagcatg gccaggaaca acagcggcag
     6721 cttgaagttg ccgtagccct ggtcggtgat cgcatagccc tgccagagtt cgcccaggcc
     6781 gttccattgg tcgggccagt gcacggcggc gatggcgacc acggtcaaca cccagaagac
     6841 gtaggccacc gcgcgcgtgg ccaggccgag cagcagcatc accgcaccca ccagttccag
     6901 ccaggtggcc agctgccagt tcagtgatgc gggcagggtg gagaacggga acgggaagcg
     6961 accttccagg tcggcgaacc agttctggcc acccagcttt tcgcgaccgg attcaaagaa
     7021 ctcccaggcc agcaggatgc gcaacgccac gggcgagagc cagcgaccga cggcgtccag
     7081 gcgaggggta tacacggaag aggcggtgct gatcatggtg gtgtcctgcg ggccagtggt
     7141 cgatggaggc catttcaggc ggcgcaggta tcggcaacgt gtgccgttgc ccggggtttt
     7201 gtcagcgact gtggccgcgg ccggggtttc ctacagtcag atacaaagac gatgcgttga
     7261 tgcacatcgg ggcgttgcgc gcccgcgcgc ggggaacgat ttccacccgg tagtgcctgg
     7321 ccgggcgcgg cgcccgaatg tatcccactg tagaaacacg cctgcgccct acagtccggt
     7381 acaactccgt gccgcggaga aacagcgccg atacatcggc aggcggaaat ggccactccc
     7441 aacaccggag tgccacccat gatccgtagc tcgttgcttg ctgccgctct cgcccttgcc
     7501 ggcgccgccg ctcccgcctt cgctacccag gccgataccg ctgcaccgcc caccgtcatc
     7561 ctggtgcacg gcgccttcgc cgatggctcc agctggagca aggtcatccg caccctgcat
     7621 gactggaaac tgccggcggt ggccgtacag aatccgctca cctcgttggc cgacgacgtc
     7681 gccgccaccc gtcgcgccat tgccgccgca ccgggcaagg tcgtgttggt cggccacagc
     7741 tggggcggca cggtcatcac cgaagcgggc gatgacccga aggtgcaggc gctggtgtac
     7801 gtggccgcgt tcgcaccgga tgccgggcag tcatcggcac agcagggcga gggcttcccg
     7861 gtcggtccgg gcctggcccg actgcaggag agggatggct acctgacctt gcccgctgat
     7921 gccatcgccc aggacttcgc gccggacgtg atgaagaagt cggccgcact gctgtacagc
     7981 acgcaggtcc cgttgaaggc cagcgcgctg ggcgaggtgg tgaacgttgc ggcatggcgc
     8041 agcaagccaa gctggtacgt gctcagccgt gacgatcgca tgctgtcgcc gcagctgcag
     8101 gccgccaccg cacgccgcat cggcgcacag ctgcagtcga tcggcagcag ccacgtgtcg
     8161 ctgctttcgc atccggcgca ggtggccgac agcatcctgg aggcggcagg cgtgaagccg
     8221 gccgaactgc cgctggccga gcaggggggc tgagcgatgg ccgcgctacg agggtatgca
     8281 ctgcccctgc tgctgggcct gctgggtgga gcggcgttgc tgctggcatg gcccggtgcc
     8341 gaggccggcg cgcagccgct cgacgcagca ccgaaggcgg ggttcggcgg tggcgggccc
     8401 tggcacaaca gcccaccgat gacactgaag cagttgcggg ggcaggtggt actggtcgag
     8461 ttctggacct acacctgcag caactgcctc aatgtggcgc cgtatgtcca ccagtggcat
     8521 gcacgctacg cgtcgcaggg cctgcaggtg atcggcgtgc atacgccgga gttcgcctat
     8581 gaagggctgc ccggcaacgt gagcagggcc atcacacggt tggatatcac ctggccggtg
     8641 gtgcaggaca accagtaccg gatctggaat gcctggggca accgcttctg gccggcactg
     8701 tacctgctcg accggcaggg gcgggtggtc tatcgccatt acggcgaggg cgactacgca
     8761 cgtaccgaaa gcgagatcca gcgcctgctg gccagcccct gagccgcgct accatggcgg
     8821 cgtcgcgcgg cgctgccccc tgccttcatc gagaacgcaa tgaatcctgt accgcacatc
     8881 cttgtcgtgg acgatgacag tgagatccgc cagatgctgg ccgactacct gcaacgcaac
     8941 ggcctgcgcg tgagccaggc cgacggtggc cgggccatgc gcgcgctgat ggacacccac
     9001 gcggtggatc tggtggtgct ggacgtgatg atgccgggcg aggacggcct gagcctgtgc
     9061 cgcaacctgc gcgccggcaa gcatcgtgcg gtgccggtgg tgctgctgac cgcccgcgac
     9121 gacgagaccg atcgcatcat cggcctggaa atgggcgccg acgattacgt gaccaagccc
     9181 ttttcctcgc gcgaactgct ggcacgcatc aatgcggtga tccgtcgcac acagatgctg
     9241 ccgccgaacc tgcaggtgag cgaagccggc cgccaactgg ccttcggtgc ctggcgcctg
     9301 gataccaccg cgcgccatct gctggatgca caggacaccg cgtatccgct cagtggtgcc
     9361 gagttccgcc tgttgcgcgt gttcctcgat cacgccaatc gcgtgctcag ccgtgaccag
     9421 ctgctcagcc tcacccaggg ccgcgatgcc gaactgttcg accgctcgat cgacctgctg
     9481 gtcagccgcg tgcggcagcg cctgggtgac gacgcacgcg agccgaccta catcaagacc
     9541 gtgcgcagcg aaggctatgt gttcagcgtg ccggtgcagt tgctggggcc ggacgaatga
     9601 acaccggcgc gcgccgtcca cgctggccgc gcacgctgtc ggcgcggctg ctgctggtgc
     9661 tgctgggcgg actggcgctg gcccacgcgc tgtccttcgg cctgctgttc ttcgaacgct
     9721 accaatccac ccgcagcatg atgctgcgca acctggatga ggatgtggca gtgagtgtcg
     9781 cgctgctgga gcacctgccc gcagagcagc gcgatgcctg ggtgccgcgg ctggagcggc
     9841 gcacctaccg ttacctgctg cgcccggcta cggcggggcc cgggctgcag accgatcgtg
     9901 cacgccaggt cactgcgatc atcgacgaca gcctgcagca ccgctatccg ctgcaggcgc
     9961 gccaggtagc tcgtttgccg gagcgcttcg aggtcgaact gcgcctgcac gacggcacgc
    10021 cgttgaccat tgaagtcacc ccgtcgggcc tgccgctggc acgctggctg cccgccgtac
    10081 tgcttgtgca gctggcgctg ctgctggtgt gcgcatggct ggcagtgcgc ctggccatgc
    10141 gcccgttgca gcagctgtcg catgcggtgg aacagctgca gccgggcaac gacggaccgg
    10201 cactgcctga agatggccct gtggaagtag gcggtgcggc ggccgcactc aacgcgctgc
    10261 aggcacgcat tcgtggccat gtcagtgagc gcctgcagat ccttgcagcg atctcgcacg
    10321 atctgcagac cccgatcacg cgcatgaagc ttcgggtgga gaccctgcct gaagacagca
    10381 cccagcagcg cctgctggcc gatctcgacc atctcgggca actggtgcgt gaaggcgtgg
    10441 cctatgcgcg cagcagccac atcgccagtg gcgcgccggt gtcgatggat ctgggcgcgt
    10501 tcctggccag tgtggtcggc gactacgagg acatgggcaa gccggtcagt ggcggtgcac
    10561 ccgctggact gatcgtgcag acctggccgc agccgctgcg acgggtggtc ggcaacctgg
    10621 tcgacaacgc agtgcgctac gccggtgccg ccgagatcga agccggccgc gatgaggctg
    10681 gcaggatatg gatccgtatt tccgaccgtg gcccgggtat cccggagaac cagctgcagg
    10741 cggtgctggc accgttccat cggctggaaa gctcgcgcaa ccgcgatacc ggcggcaccg
    10801 gcctgggcct ggccatcgcg gtgcagctgg cgcagtcgct gggcgg
//
