LOCUS       NZ_CP085300            21086 bp    DNA     linear   CON 18-JAN-2024
DEFINITION  Streptomyces sp. BSE6.1 chromosome, complete genome.
ACCESSION   NZ_CP085300
VERSION     NZ_CP085300.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. BSE6.1
  ORGANISM  Streptomyces sp. BSE6.1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8024389)
  AUTHORS   Ramesh,C., Anwesh,M., Vinithkumar,N.V., Kirubagaran,R. and
            Dufosse,L.
  TITLE     Complete Genome Analysis of Undecylprodigiosin Pigment
            Biosynthesizing Marine Streptomyces Species Displaying Potential
            Bioactive Applications
  JOURNAL   Microorganisms 9 (11), 2249 (2021)
   PUBMED   34835376
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8024389)
  AUTHORS   Chatragadda,R. and Maile,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2021) Andaman and Nicobar Centre for Ocean Science
            and Technology, National Institute of Ocean Technology, Dollygunj,
            Port Blair, Andaman and Nicobar Islands 744103, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-OCT-2021
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/18/2024 07:10:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,273
            CDSs (total)                      :: 7,198
            Genes (coding)                    :: 7,094
            CDSs (with protein)               :: 7,094
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 47 of 104
            Pseudo Genes (incomplete)         :: 80 of 104
            Pseudo Genes (internal stop)      :: 9 of 104
            Pseudo Genes (multiple problems)  :: 30 of 104
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:03:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2839951
            Orig. end                         :: 2861037
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP085300.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of Ocean
            Technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="17"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(57..72)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: strong, score: 24.16"
                     /tool="antismash"
     gene            205..969
                     /locus_tag="LJA35_RS12325"
     CDS             205..969
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="LJA35_RS12325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_003973740.1"
                     /transl_table=11
                     /translation="MSTDVSSAENEGGATVRTARVPKYYRLKKHLLDMTRTQTPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYITADDRLAGLLDITAGGRVLRIERLRMANGEPMAIETTHLSAKRF
                     PALRRSLVKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SQDRTGQPVEWVRSVYRGDRYKFVARLKRPQD"
     misc_feature    1041..1055
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     gene            1126..1413
                     /locus_tag="LJA35_RS12330"
     CDS             1126..1413
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130766.1"
                     /locus_tag="LJA35_RS12330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_165288062.1"
                     /transl_table=11
                     /translation="MSEDTEVSREPVVTPVRVVIGLCLVAPFVAMLWVGSYTKTDPTFI
                     GIPFFYWYQMAWVLISTLLTVTAYKLWQRDQRGRAAAHSAPAASKGGESR"
     gene            1410..3020
                     /locus_tag="LJA35_RS12335"
     CDS             1410..3020
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444565.1"
                     /locus_tag="LJA35_RS12335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_165288061.1"
                     /transl_table=11
                     /translation="MNDGVNGVALAVFIFFFVLVTAMGFMAARWRRAENEHSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFIKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDDIFASASDKFTESGKGGVVPDSGGQWTYATLALGSALALFMYPHSITATLSSRSREV
                     IRRNTTILPLYSLMLGLLALLGFMAIAAGVKVENGQLAIPQLFENMFPDWFAGVAFAAI
                     GIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPQQETKVSKLVSLLVKVGALIFVLGM
                     DKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLGGWAVGMVYGTVAAYGVASPT
                     QKHFGGSSDEIPGIGEIGYIGLTAFVLNVLVTVVLTFVLKAVKAPDGVDETRPSDYTAD
                     AGDPGVQVELPPATAGSSH"
     gene            3094..3600
                     /locus_tag="LJA35_RS12340"
     CDS             3094..3600
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="LJA35_RS12340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_165288060.1"
                     /transl_table=11
                     /translation="MDFVIRRAAAEEYDTLGEITAQAYLRDGLLDFGESDSYLDELRNV
                     AKRAAAAEVLVAAADGRVLGGVTFVPSGGPMADIARPGEAEIRMLAVAREARGRGAGEA
                     LVRACVDRARTVAGCTGVVLSTQAAMHTAHRLYERLGFVRTPGRDWNPLPELDDIMLLA
                     YELTL"
     misc_feature    3627..3641
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     misc_feature    3658..3672
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     regulatory      3659..3837
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    3666..3679
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     gene            3936..6344
                     /locus_tag="LJA35_RS12345"
     CDS             3936..6344
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444560.1"
                     /locus_tag="LJA35_RS12345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_233645729.1"
                     /transl_table=11
                     /translation="MTIAPADPASAKPVTAPAAPGSADPTTGEPDGPGAALLRTLTGLT
                     ADLQDADPGRVAAAALRGRSAHADEAELRELATEAAAGLISEDPVYSRLAARLLTLGIR
                     AEAASQGVVTFTDSVATGHREGLIADRTAAFVRQHADRLDALIDPDADDRFGYFGLRTL
                     YSRYLLRHPITRKAVETPQHFLLRVAAGLAEDDTARSVDEVAALYGLMSRLDYLPSSPT
                     LFNSGTRHAQMSSCYLLDSPRDELDSLYDRLHQVARLSKHAGGIGIAYSRVRARGSLIR
                     GTNGHSNGIVPFLKTLDASVAAVNQGGRRKGAAAVYLETWHADVEEFLELRDNTGEDAR
                     RTHNLNLAHWIPDEFMRRVDADGTWSLFSPADVPELTDLWGEEFDAAYRRAEEAGLARR
                     TLPARELYGRMMRTLAQTGNGWMTFKDTANRTANQTATPGHVVHSSNLCTEILEVTDDG
                     ETAVCNLGSVNLGAFVDPANGDMDWERLDATVRTAVTFLDRVVDINYYPTEQAGRSNAR
                     WRPVGLGAMGLQDVFFQLRLPFDSPEARALSTRIAERIMLAAYETSADLAERSGPLPAW
                     EKTRTAKGVLHPDHYGVEPAWPERWAALRERMATTGLRNSLLLAIAPTATIASIAGVYE
                     CIEPQVSNLFKRETLSGEFLQVNSYLVDDLKRLGVWDARTREALREANGSVQGFGWIPE
                     DVRALYRTAWEIPQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKQGLK
                     TTYYLRSRPATRIARAAARATAPVPVQAGPDPEAVACSLENPESCEACQ"
     gene            6344..7375
                     /locus_tag="LJA35_RS12350"
     CDS             6344..7375
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973746.1"
                     /locus_tag="LJA35_RS12350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_102930970.1"
                     /transl_table=11
                     /translation="MTTETPANPTTKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWHV
                     EEVDLHSDVADLAKLSPEEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLS
                     RQLFEEAVHVQFYLTLLDTYLPDPDDRAAAFAAVENIPSIREKAGFCFKWMDSVESIDR
                     LETKADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMH
                     MSFAFDVVDTVRKEEPELFDDALRQEVTDMLREAVEAELQFARDLCGDGLPGMNTDSMR
                     QYLECVADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLD
                     EDF"
     gene            complement(7288..7542)
                     /locus_tag="LJA35_RS12355"
     CDS             complement(7288..7542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973747.1"
                     /locus_tag="LJA35_RS12355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_233645730.1"
                     /transl_table=11
                     /translation="MTGNQIEGLVGMLATFGLLVLMVLPSVIGIVRDRRIDRRIREAQE
                     GRGRGKETQKTQKSSSRSTVPSTATWYAEGRRSKKLVNS"
     gene            7635..8603
                     /locus_tag="LJA35_RS12360"
     CDS             7635..8603
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030121.1"
                     /locus_tag="LJA35_RS12360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_233645731.1"
                     /transl_table=11
                     /translation="MLRNVAAVLLDGAHPFELGVICEVFGIDRSDEGLPGYDFAVVSAE
                     GPTLGTHVGGLTVSTPYGLERLEEADLIAVPAGSDFVRREYPPELLDALRRATDRGTRV
                     LSVCSGVFVLAAAGLLDGRRCAVHWHHAAELARQYPRARVAPDVLYVDEDPVITSAGTA
                     AGIDACLHIVRKEQGPEVANRIARRMVVPPHRDGGQAQYIERPLPRSSCDTVGEVLAWM
                     EQHLDEEVTVEQLAARAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQRLLEATDETM
                     DTIAWRAGFGTAAALRHQFVRTLGTTPHAYRRTFRGPEAAA"
     gene            complement(8619..10004)
                     /locus_tag="LJA35_RS12365"
     CDS             complement(8619..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="LJA35_RS12365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_102930967.1"
                     /sec_met_domain="p450 (E-value: 3.1e-70, bitscore: 235.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVNPETRAPAAPGAPELREPPVAGGGVPLLGHGWRLARDPL
                     AFMSQLRDHGDIVRIKLGPKTVYAVTNPELTGALALNPDYHIAGPLWESLEGLLGKEGV
                     ATANGPLHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWQPGKTVDATSESFRVAV
                     RVAARCLLRGQYMDERAERLCVALATVFRGMYRRMVVPLGPLYRLPIPANRRFNDALAD
                     LHLLVDEIIAERRASGQKPDDLLTALLEAKDDNGDPIGEQEIHDQVVAILTPGSETIAS
                     TIMWLLQALADHPEHADRIRDEVEAVTGGRPVAFEDVRKLAHTGNVILEAMRLRPAVWV
                     LTRRAVAESELGGYRIPAGADIIYSPYAIQRDPKSYDRNLEFDPDRWLPERAKNVPKYA
                     MKPFSAGKRKCPSDHFSMAQLTLITAALATKYRFEQVAGSNDAVRVGITLRPHDLLVRP
                     VAR"
     gene            complement(10001..11086)
                     /gene="cyc1"
                     /locus_tag="LJA35_RS12370"
     CDS             complement(10001..11086)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="LJA35_RS12370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_212731146.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-63, bitscore: 214.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHAFSHGTTATPTAIAVPSSLRLPVIEAAFPRQLHPYWPRLQEAT
                     RAWLLEKRLMPADKVEEYADGLCYTDLMAGYYLGAPDEVMQAIADYSAWFFVWDDRHDR
                     DIVHGRPGAWRRLRARLHTALDSPGDHLHHEDTLVAGFADSVRRLYAFLPATWNARFAR
                     HFHAVIEAYDREFHNRTRGIVPGVEEYLELRRLTFAHWIWTDLLEPSSGCELPDAVRKD
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHHSLTLEEAIGEVRRRVE
                     ECITEFIAAEQEALRFADSLADGTVRGKELSGAVRANVGNMRNWFSSVYWFHHESGRYM
                     VDSWDDRSTPPYVNNEAAGEK"
     misc_feature    complement(10202..10204)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11346..11996)
                     /gene="def"
                     /locus_tag="LJA35_RS12375"
     CDS             complement(11346..11996)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925882.1"
                     /locus_tag="LJA35_RS12375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide deformylase"
                     /protein_id="WP_233645732.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHPGVLPVDDEGFVVDTQDCEEREADWRGRGTSRPIT
                     VVGNPVLHKECEDVTDFGEEFQQLVADMFASQRTAEGVGLAANQIGVSKKVFVYDCPDD
                     EGVRHVGVVCNPKLVELPADRRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEKGNPV
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVANG"
     misc_feature    complement(12058..12074)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 22.77"
                     /tool="antismash"
     gene            complement(12150..13130)
                     /locus_tag="LJA35_RS12380"
     CDS             complement(12150..13130)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="LJA35_RS12380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_102930966.1"
                     /transl_table=11
                     /translation="MRIFGKARHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRDAGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRTPGDATDAGEPLGMDLGSAAVRLSPEGEAEVVWGRRLDPARVEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSAGHSYPVFDEIELWAPSPVPTWVVLLEAATEADRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGEGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPAGLVKGLLDGWVADSPDSRDWRDLEEVC"
     gene            complement(13244..14509)
                     /locus_tag="LJA35_RS12385"
     CDS             complement(13244..14509)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973753.1"
                     /locus_tag="LJA35_RS12385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metal-dependent phosphohydrolase"
                     /protein_id="WP_212731144.1"
                     /transl_table=11
                     /translation="MTPSPPPAQSPPSVALLLVPGCAGLLALGCLASVLVSGPVQRPVA
                     LAFGGLVALGELTRRTGTEAREAAPLGAAGALAYALLGDVAGQPAHHGVAQTVTVVLAA
                     SLLGSVPYVARGSGPVLDHLARRVLTVAFAAVCFRPLSNQGVFDYWSGPAYALLLIALL
                     ALTTLCDAVLAAAPAHARTGWPFGPLLREELRGMVGITSAVCATGAVMALAVSVAGLWA
                     LPVFCVPLLLAQLSYRRYAAVRATYRQTIASLARATEIAGYTPAGHARRVAGLGVAVGR
                     DLGLSGAELTVLEYAALMHDIGQLSLVDPVPAGATADLPVTEQRRIALLGGAVVRQTGV
                     DAAVAVVVERQADPCREQPVAARIVRVVNAYEEKARDAGPGGVLTALEELRLATAGDYA
                     PEVVEALARVLSRGSLTGPSAG"
     gene            complement(14506..15831)
                     /locus_tag="LJA35_RS12390"
     CDS             complement(14506..15831)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973754.1"
                     /locus_tag="LJA35_RS12390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_233645733.1"
                     /transl_table=11
                     /translation="MDAVPARARAYVVCVALVAVLCLRPLPSVHAPWWAVLLLAGVYAG
                     SELVARSRFVGTCYPVLLAGAFLLPPPAAALVALPGALLSPVPRRPFGLRRVWRAAQLT
                     LAVWAAACVHWRLGGRDAVVEPAFPYALVPAGAAVLAFCLVLTVLDGGILTLADRVPPS
                     RAWRGLFSRSLAPIAVHGLAGLMMAVLWRSPYGPVAALLVLLPMCVAWWAFAQYHRERA
                     AHQATIRALVQAVDIKDGYTRGHSERVGQASMMIARELGMDDERVETLRFAGILHDVGK
                     LGVPTRLLRKDGPLTPEERRVIELHPEYGHEMVRGIRFLGEARAAVLHHHERLDGSGYP
                     YGLAGDRIPESARVVAVADAFDAMTSTRSYSRARPVAVALQELQRCAGAQFDPRMVRAL
                     VRALGRHGWRPSVTADGTPTLPAAPSPGRGEGARDSVGRGAP"
     gene            complement(15970..16281)
                     /gene="rsrA"
                     /locus_tag="LJA35_RS12395"
     CDS             complement(15970..16281)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="LJA35_RS12395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_102928303.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDKEMPDSDCVKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGQDDVPGDLRSKVMGRLDLIRSGQSVPEHDVTATPSAPQES"
     gene            complement(16278..16961)
                     /gene="sigR"
                     /locus_tag="LJA35_RS12400"
     CDS             complement(16278..16961)
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="LJA35_RS12400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_102928304.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAEQPEGRGTGAESAAERSARFERDALEFLD
                     QMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKK
                     QREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKQALQAIPEEFRIAV
                     YLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGLVPAGAGESNEA
                     KGSGS"
     misc_feature    complement(16924..16939)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     misc_feature    17017..17031
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            complement(17219..17854)
                     /locus_tag="LJA35_RS12405"
     CDS             complement(17219..17854)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973757.1"
                     /locus_tag="LJA35_RS12405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_233648256.1"
                     /transl_table=11
                     /translation="MTEAVETDAGPARITWHWARRPRLVLAVSHGAGGGIEARDLRALA
                     GALPAHGVSVALVEQPWRVAGKKLAPAPKTLDTGWRGVWPALAAPGLPVISGGRSAGAR
                     VACRTAAELGAHAVLALSFPLHPPGKPEKSRAAELLGAGVPTLVVQGGNDPFGRPAEFP
                     AAPEGTYDLVEVPYGDHGFAVPKRAGISQERALELITDGVLKWTGSLG"
     gene            complement(17877..18692)
                     /locus_tag="LJA35_RS12410"
     CDS             complement(17877..18692)
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="LJA35_RS12410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_102928306.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGIFEIEKWEPKESLEPDYNVAPTKEVYAVL
                     DRPLKDVEDPKPVRQLRKLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFSTRR
                     CILPADGYYEWVTGKQERDLEVEGRKKRPRKQPYFVTPADGSVFAMAGLYEFWRDRTLP
                     DDHPQAWWVTCSVITTEAETAPLAVAPADGPHALADIHPRMPLMLTPDRWDDWLDPART
                     DPDELTSLLAPPPTGLMRAFPVSTAVSNVRNNGPELLKELEAPEEGTLF"
     gene            18743..19465
                     /locus_tag="LJA35_RS12415"
     CDS             18743..19465
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973759.1"
                     /locus_tag="LJA35_RS12415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_102928307.1"
                     /transl_table=11
                     /translation="MDHLATASLTSLWDEVSGTQPDPDLWVVIATLVAALAVVLTRGSW
                     RIARNAITIAHEGGHGLVALLTGRTLTGITLHSDTSGLTVSRGKPHGLGMILTAVAGYT
                     APPLLGLGGAALLAAGRITLLLWLATALLVALLVMVRNAYGVLTVVVTGGTFVLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRARGGAGDSDADQLARLTHAPAGVWFFLF
                     HAVSLCSLIGGGRWLLEL"
     gene            19631..20947
                     /gene="aroA"
                     /locus_tag="LJA35_RS12420"
     CDS             19631..20947
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016824681.1"
                     /locus_tag="LJA35_RS12420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_102928308.1"
                     /transl_table=11
                     /translation="MTVNPAHTALWPAPHASGAVDATVHVPGSKSVTNRALVLAALASE
                     PGWLRRPLRSRDTVLMAEALRAMGVEIEEGVGPDGTGEFWRVIPAGLRGPATVDVGNAG
                     TVMRFLPPVATLVDGPVRFDGDPRSYERPLHGVIDALRVLGARIDDDGRGSLPLTVQGG
                     GALEGGPVEIDASSSSQFVSALLLSGPRFNQGVEVRHTGSALPSMPHIRMTVDMLRAVG
                     AQVDTPESGGEPNVWRVTSGALLGRDLTIEPDLSNAQPFLAAALVTGGKVLIPDWPSRT
                     TQPGDRLREIFTEMGGSCELTDFGLVFTGSGTIHGIDVDLGEVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRRLHGGVFHTYEDHRM
                     ATAGAVIGLAVEGVQIENVATTAKTLPDFPDLWTGMLGA"
ORIGIN
        1 ccgaatggcg cgccggccgg cccccgaacg cgcgtaccag cggcgtccga ccccgctgtg
       61 gactagacca agggtgttcc cgcgggtata cagaagggat cacggagcgt gcgggggcca
      121 tcccggcacg aagccgtgcc acgatgtgag ccgtggccga cagggaagcg gtcgcttcgg
      181 cacccggagc cgggaaggca gagcatgagc accgacgtca gcagtgcgga gaacgagggt
      241 ggggcgaccg tccgtaccgc gcgcgtgccc aagtactacc gtctgaagaa gcatctgctc
      301 gacatgaccc ggacccagac gccgggcaca ccggtcccgc ccgagcgcac gctggccgcc
      361 gagttcgaca cctcgcgcac gacggtgcgc caggccctgc aggagctggt cgtcgagggc
      421 cgcctggagc gcatccaggg caagggcacc ttcgtcgcca agcccaaggt gtcgcaggcg
      481 ctgcaactca cctcctacac cgaggacatg cgggcccagg gcctcgaacc cacctcgcag
      541 ctgctggaca tcggctacat caccgccgac gaccggctcg ccgggctgct ggacatcacg
      601 gccggcggcc gggtgctgcg catcgagcgg ctgcgcatgg ccaacggcga gccgatggcg
      661 atcgagacca cccacctcag cgcgaagcgc ttcccggcgc tgcggcgttc cctggtgaag
      721 tacacgtccc tctacaccgc gctcgccgag gtgtacgacg tccacctcgc cgaggccgag
      781 gagaccatcg agacctccct ggccaccccg cgcgaggccg gcctgctcgg caccgacgtc
      841 ggcctgccca tgctgatgct ctcccggcac tcgcaggacc gcaccggtca gccggtggaa
      901 tgggtccgct cggtgtaccg gggcgaccgc tacaagttcg tggcccgcct caagcgcccc
      961 caggactagg accggcccgg cacatacccg gtatgtcccc ccacgcgcgg gcgcgaagtt
     1021 gcggttgagg accgatatac ggacgaggtc ttccgctgtc ttgacgccgt cacctacatt
     1081 tcgtgcgcac tgcacgaggt gatcagcgag gggacggagc cgcgcatgtc agaagacaca
     1141 gaagtgagca gagagccggt ggtgacgccg gtgcgcgtcg tcatcgggct ctgtctcgtc
     1201 gcaccgttcg tggccatgct ctgggtcggt tcgtacacga agacggaccc gaccttcatc
     1261 ggcatcccgt tcttctactg gtaccagatg gcctgggtgc tgatctccac cctgctcacg
     1321 gtcaccgcgt acaagctgtg gcagcgcgac cagcgcggac gcgccgccgc ccactccgcc
     1381 cccgctgcct cgaagggcgg tgagtcgcga tgaacgacgg cgtgaacggc gtcgcactcg
     1441 ccgtcttcat cttcttcttc gtcctcgtca ccgccatggg cttcatggcc gcccgctggc
     1501 gccgggccga gaacgagcac agcctcgacg agtggggcct gggaggccgc tcgttcggca
     1561 cctgggtcac ctggttcctg ctgggcggcg acctgtacac cgcgtacacc ttcgtggccg
     1621 tcccggcggc gatctacgcg gcgggcgcgt ccggcttctt cgcggtgccg tacacgatcc
     1681 tggtctaccc gctgatcttc accttcctgc cccgcctgtg gtcggtctcg cacaagcacg
     1741 ggtacgtgac gacctcggac ttcgtgcgcg gccggttcgg ctccaagggc ctgtcgctgg
     1801 cggtggccgt gaccggcatc ctggcgacca tgccgtacat cgcgctccag ctggtcggca
     1861 tccaggccgt cctcgacgtg atgggcgtcg gcggcggcga ggacaccaac tggttcatca
     1921 aggacctgcc gctgctgatc gccttcggtg tgctggcggc gtacacctac tcgtcgggac
     1981 tgcgggcgcc cgcgctgatc gcgttcgtga aggacacgct gatctacatc gtcatcgcgg
     2041 tggcgatcat ctacatcccg atcaagctgg gcggcttcga cgacatcttc gcgtcggcga
     2101 gcgacaagtt caccgagtcg ggcaagggtg gagtggtgcc cgactcgggg ggccagtgga
     2161 cgtacgcgac gctggcgctc ggttcggcac tggcactgtt catgtacccg cactcgatca
     2221 ccgccacgct gtcctcgcgc agccgtgagg tgatccgccg caacaccacg atcctgccgc
     2281 tgtactcgct gatgctgggc ctgctggcgc tgctgggctt catggcgatc gcggccgggg
     2341 tcaaggtgga gaacggccag ctggcgatcc cgcagctgtt cgagaacatg ttcccggact
     2401 ggttcgcggg cgtggccttc gcggcgatcg gcatcggcgc cctggtcccg gcggcgatca
     2461 tgtccatcgc ggccgcgaac ctcttcaccc gcaacatcta caaggacttc atcaagccgg
     2521 acgccacgcc gcagcaggag accaaggtct ccaagctggt gtcgctgctg gtgaaggtgg
     2581 gcgcgctgat cttcgtcctg ggcatggaca agaccgtcgc gatcaacttc cagctgctgg
     2641 gcggcatctg gatcctgcag accttcccgg ccctggtcgg cggcctgttc acccgctggt
     2701 tccaccgctg ggcgctgctc ggcggctggg cggtcggcat ggtctacggc acggtcgccg
     2761 cctacggtgt ggcctcgccg acgcagaagc acttcggcgg ctcctccgac gagatccccg
     2821 gcatcggcga gatcggctac atcggcctca ccgccttcgt gctgaacgtg ctggtcaccg
     2881 tggtcctgac cttcgtcctg aaggcggtca aggcgcccga cggcgtcgac gagacccggc
     2941 cgagcgacta cacggcggac gccggcgacc ccggcgtcca ggtggaactg ccgccggcca
     3001 cggcgggcag ctcgcactag cggcgctctc ttcagcgggc cgtcggagaa atccggcggc
     3061 ccgtcgtcgt gcccgtgggg cacactcggc ggcatggact tcgtgattcg gcgggcggcg
     3121 gccgaggagt acgacaccct cggcgagatc accgcgcagg cctacctgcg cgacgggctc
     3181 ctcgacttcg gggagagcga ctcgtacctg gacgagctgc ggaacgtggc caagcgcgcc
     3241 gcggccgcgg aggtgctggt cgcggcggcg gacggccggg tgctcggcgg cgtgaccttc
     3301 gtgccgtccg gcggccccat ggcggacatc gcgcgtcccg gcgaggccga gatacgcatg
     3361 ctcgccgtcg cccgcgaggc gcgcggccgc ggggcgggcg aggccctggt gcgggcctgc
     3421 gtggaccgcg cccggacggt ggccggttgc acgggcgtcg tgctgtcgac gcaggccgcc
     3481 atgcacaccg cgcaccgcct ctacgagcgt ctgggcttcg tccgcacgcc cggccgcgac
     3541 tggaatcccc tgccggagct ggacgacatc atgctgctcg cctacgaact gacgctgtga
     3601 acccgaagcg gtgaactgac gcgctgacac aacatctggg ggtgctggcg aagtccggca
     3661 caagatgtat gctcatgctc gctgtcgccg caggggaatc cggtgcgaat ccggaactgt
     3721 cccgcaacgg tgtacttgcg tgcatccgta cgtcttcgca cgtgcgcgca cgcctgttca
     3781 gtccaaggac ctgccgacag tgcgcccggc cgccccggcc cgggtgccat acgtccgggc
     3841 ctcgtggagt gggccggtgg acgcgacgcc gtgcgcgctc gtgagctgcc ccctgccctc
     3901 tcccaggccc cgtgccgagc gagggagtgc tccacgtgac catcgcgcca gcggacccgg
     3961 cttcagcgaa accggtgacg gctccggccg cccctggatc cgccgacccc accaccgggg
     4021 aacccgacgg acccggtgcc gccctgctgc ggaccctgac cgggctgacc gccgacctcc
     4081 aggacgccga ccccggccgg gtggccgccg ccgcgctgcg gggccggtcc gcccacgccg
     4141 acgaggcgga gttgcgcgag ctggccaccg aggcggccgc cggtctgatc tccgaggacc
     4201 cggtctactc ccggctggcc gcccgcctgc tgaccctcgg catccgcgcc gaggccgcct
     4261 cgcagggcgt cgtgacgttc accgactcgg tcgccaccgg ccatcgcgag ggcctgatcg
     4321 ccgaccgcac ggccgccttc gtacggcagc acgcggaccg cctggacgcg ctgatcgacc
     4381 cggacgccga cgaccgcttc ggctacttcg gactgcgcac cctgtacagc cgctatctgc
     4441 tccgccaccc gatcacccgc aaggccgtcg agacgcccca gcacttcctg ctccgggtcg
     4501 ccgccggact cgccgaggac gacaccgcgc ggtccgtgga cgaggtcgcc gccctgtacg
     4561 gcctgatgag ccgcctggac tacctcccgt cctcccccac cctcttcaac tccggcaccc
     4621 ggcacgccca gatgtcgtcc tgctacctcc tggactcccc cagggacgag ttggactccc
     4681 tctacgaccg cctccaccag gtggcccgcc tgtccaagca cgcgggcggc atcggcatcg
     4741 cctactcccg tgtccgcgcc cggggttcac tgatccgcgg caccaacggg cactccaacg
     4801 gcatcgtccc gttcctgaag acgctggacg cctcggtggc ggccgtgaac cagggcggcc
     4861 ggcgcaaggg cgcggcggcg gtctacctgg agacctggca cgcggacgtc gaggagttcc
     4921 tggagctgcg ggacaacacc ggcgaggacg cccgccgcac gcacaacctg aacctggcgc
     4981 actggatccc ggacgagttc atgcgccgcg tggacgccga cgggacctgg tcgctgttct
     5041 cccccgccga cgtgccggag ctgaccgacc tgtggggcga ggagttcgac gcggcctacc
     5101 gcagggcgga ggaggcgggg ctcgcccgca ggacgctgcc cgcccgtgag ctgtacggcc
     5161 gcatgatgcg caccctcgcg cagaccggca acggctggat gaccttcaag gacaccgcca
     5221 accgcacggc caaccagacc gcgacccccg gccacgtcgt ccactcctcc aacctctgca
     5281 cggagatcct ggaggtcacc gacgacgggg agacggcggt ctgcaacctg ggctcggtca
     5341 acctcggcgc cttcgtcgac cccgcgaacg gcgacatgga ctgggagcgc ctggacgcca
     5401 ccgtccgcac cgcggtcacc ttcctggacc gggtggtcga catcaactac tacccgaccg
     5461 agcaggcggg ccgctccaac gcccgctggc gcccggtcgg cctcggcgcg atgggtctcc
     5521 aggacgtctt cttccagctc cggctgccct tcgactcccc cgaggccagg gccctgtcca
     5581 cccgcatcgc cgagcggatc atgctcgccg cgtacgagac ctccgccgac ctcgccgagc
     5641 ggagcggccc gctgccggcc tgggagaaga cccgcacggc caagggtgtg ctgcacccgg
     5701 accactacgg cgtcgagccc gcctggccgg agcgctgggc cgcgctgcgc gagcgcatgg
     5761 cgacgaccgg gctgcgcaac tccctgctcc tggccatcgc gccgaccgcg accatcgcct
     5821 ccatcgccgg tgtctacgag tgcatcgagc cgcaggtctc caacctgttc aagcgcgaga
     5881 cgctgtcggg cgagttcctc caggtcaact cctacctggt ggacgacctc aagcggctcg
     5941 gcgtgtggga cgcccgcacc cgtgaggcgc tgcgcgaggc caacggctcg gtgcagggct
     6001 tcggctggat ccccgaggac gtgcgcgcgc tgtaccgcac cgcctgggag atcccgcagc
     6061 gcggcctgat cgacatggcc gccgcccgca ccccgtacct cgaccaggcc cagtcgctga
     6121 acctgttcct ggagacgccg accatcggca agctctcctc gatgtacgcc tacgcctgga
     6181 agcagggtct gaagaccacg tactacctgc gttcccgccc ggcgacccgg atcgcccgcg
     6241 ccgcggcccg agccaccgcc cccgtccccg tgcaggccgg cccggacccc gaagcggtcg
     6301 cctgctccct ggaaaacccc gagtcctgcg aggcctgcca gtaatgacca ccgagacccc
     6361 cgcgaacccc accaccaaga acctgctcga cccgggcttc gaactgaccc tgcgccccat
     6421 gcgctacccc gacttctacg agcgctaccg ggacgccatc aagaacacct ggcacgtcga
     6481 ggaggtcgac ctccactcgg acgtcgccga cctggccaag ctcagccccg aggagcagca
     6541 cctgatcggc cgactggtgg ccttcttcgc caccggcgac tcgatcgtcg cgaacaacct
     6601 ggtgctgacg ctgtacaagc acatcaactc ccccgaggcg cggctgtacc tgtcccgcca
     6661 gctcttcgag gaggccgtcc acgtccagtt ctatctgacg ctcctcgaca cctacctgcc
     6721 cgacccggac gaccgggccg ccgccttcgc ggccgtggag aacatcccgt ccatccggga
     6781 gaaggccggg ttctgcttca agtggatgga ctcggtcgag tcgatcgacc gcctggagac
     6841 caaggccgac cggcgccgct tcctgctgaa cctgatctgc ttcgccgcgt gcatcgaggg
     6901 cctgttcttc tacggcgcct tcgcctacgt ctactggttc cgcagccgcg gtctgctgca
     6961 cggtctggcc accggcacca actgggtgtt ccgggacgag accatgcaca tgtccttcgc
     7021 gttcgacgtg gtcgacaccg tgcgcaagga ggagccggag ctgttcgacg acgcgctccg
     7081 gcaggaggtc accgacatgc tgagggaggc cgtcgaggcc gagctgcagt tcgcgcgcga
     7141 cctgtgcggt gacggcctcc cggggatgaa caccgactcg atgcggcagt acctggagtg
     7201 cgtggccgac cagcgtctga cgcggctcgg cttcgccccg gtgtacggct ccgagaaccc
     7261 cttctccttc atggaactgc agggtgttca ggagttgacc aacttcttcg agcggcgccc
     7321 ctcggcgtac caggtggcgg tggagggcac cgtcgacctg gacgaggact tctgagtctt
     7381 ctgggtttcc tttccccgac ccctcccctc ctgggcctcc ctgatccggc ggtcgatgcg
     7441 cctgtcgcgc acgatgccga tcacggaggg gaggaccatg aggacgagga gtccgaaggt
     7501 cgcgagcatt ccgacgaggc cttctatctg gtttccggtc atgacaccac tgtcgcgccg
     7561 gagactcctt accgtcagtg gcaggactgc cgtaagacct cgatttcctg ccaccggcga
     7621 ggcacactgg cggcatgctg cggaacgtgg cggccgtcct gctggacggt gcgcatccct
     7681 tcgaactcgg cgtgatctgc gaggtcttcg gcatcgaccg gagcgacgag ggcctgccgg
     7741 ggtacgactt cgcggtggtc tccgcggagg gacccacgct gggcacccac gtcggcgggc
     7801 tgaccgtctc cacgccgtac ggtctggagc ggctggagga ggccgacctg atcgcggtcc
     7861 cggcgggcag cgacttcgtc cgccgggagt acccgcccga gctgctggac gccctgcgca
     7921 gggcgacgga ccggggcacc cgcgtgctga gcgtgtgctc cggcgtcttc gtgctggccg
     7981 ccgccggtct gctggacggg cggcggtgcg cggtgcactg gcaccacgcg gccgagctgg
     8041 cccggcagta cccgcgggcg cgggtcgcgc cggacgtgct ctacgtcgac gaggacccgg
     8101 tgatcacctc cgccggaacg gccgccggca tcgacgcctg cctgcacatc gtgcgcaagg
     8161 agcaggggcc ggaggtcgcc aaccgcatcg cccggcgcat ggtggtgccg ccgcaccggg
     8221 acggcggaca ggcgcagtac atcgaacggc cgctgccgcg ctcctcctgc gacaccgtcg
     8281 gcgaggtgct ggcctggatg gaacagcacc tcgacgagga ggtcaccgtc gagcagctcg
     8341 cggcccgggc gcacatgtcc ccgcgcacct tcgcccgccg cttccagcag gagacgggta
     8401 cgactcccta ccgctggatc ctgcgccagc gggtgctgct ggcccagcgg ctgctggagg
     8461 cgacggacga gacgatggac acgatcgcct ggcgcgccgg tttcggcacg gcggcggccc
     8521 tgaggcacca gttcgtccgg accctgggca ccaccccgca cgcctaccgg cgcaccttcc
     8581 ggggcccgga ggccgccgcc tgatccgtca cggtcgcgtc atcgcgccac gggcctgacc
     8641 agcaggtcgt gcgggcgcag cgtgatgccg acgcgtaccg cgtcgttgga gcccgccacc
     8701 tgctcgaagc ggtacttcgt ggcgagcgcg gccgtgatca gcgtgagctg ggccatcgag
     8761 aagtggtcac tggggcactt ccgcttgccc gcactgaaag gcttcatggc gtatttcggc
     8821 acattcttcg cgcgttccgg gagccagcgg tccgggtcga actccaggtt gcggtcgtac
     8881 gacttcggat cgcgttggat tgcgtacgga ctgtagatga tgtccgcacc ggccggaatg
     8941 cgatagccac cgagttcgct ctcggccacc gcgcgccgcg tcaataccca tacggcgggg
     9001 cgcaaacgca tggcctccag gatgacattg ccggtgtgcg cgagcttgcg gacgtcctcg
     9061 aatgccacgg ggcgccctcc ggtcaccgct tcgacttcgt cgcgtatgcg gtcggcatgt
     9121 tccggatggt cggcaagtgc ctggagcaac cacatgatcg tggacgcgat ggtttcactg
     9181 cccggggtga gtatcgcgac cacctggtcg tggatctcct gttccccgat cgggtcgcca
     9241 ttgtcgtcct tcgcctccag caatgccgtg agcaaatcgt ccggcttttg accggatgca
     9301 cggcgctcgg cgatgatctc gtcgaccagc agatgcagat cggccaacgc gtcgttgaat
     9361 cggcggttgg ccggaatcgg cagccggtac agcggtccga gcgggaccac catgcgccgg
     9421 tacatgcccc ggaagacggt ggcgagcgcg acgcacagcc gctcggcccg ctcgtccatg
     9481 tactgcccgc gcagcagaca gcgggccgcg acgcgcacgg cgacccggaa ggactcggag
     9541 gtcgcgtcga cggtcttccc cggctgccag cgctcggtga gcgcgtgcgc ctcctcctcc
     9601 atgatcggcc cgtaggcggg gatggcgtcg agccggaagg ccggctggat ggtgcgccgc
     9661 tggcggcggt ggagcggccc gttggcggtg gccacgccct ccttgccgag caggccctcc
     9721 agcgactccc acagcgggcc ggctatgtgg tagtcggggt tcagggcgag ggcgccggtc
     9781 agctccgggt tggtgaccgc gtagacggtc ttcgggccga gcttgatgcg cacgatgtcg
     9841 ccgtggtcgc gcagctggga catgaaggcc agcgggtcgc gggccagtcg ccagccgtgg
     9901 ccgagcagcg gcacgccgcc gcccgcgacg ggcggttcac gcagctccgg tgctccgggg
     9961 gccgcgggtg cgcgggtttc ggggttgacg gactcgacgg tcatttctca cctgccgctt
    10021 cgttgttgac gtacgggggc gtggaccggt cgtcccagct gtcgaccatg taccggccgg
    10081 actcgtggtg gaaccagtag acggaactga accagttccg catattgccg acgttggccc
    10141 gcacggcgcc gctcagttcc tttccgcgta cggttccgtc ggcgagcgag tcggcgaacc
    10201 gtaaggcttc ctgctccgcg gcgatgaatt cggtgatgca ttcctcgacg cgtcgccgga
    10261 cttctccgat ggcttcttcg agcgtgagtg aatgatgggt gatgagactg atgccgagat
    10321 tgtggacctc gtctcccgct atttccttcg gcagtgagca gaggtcgttg taccaggcgg
    10381 cgaattcctg actcagcagc gccgcccggc gatatgccgg gtctttccgt acggcgtcgg
    10441 ggagttcgca gcccgagctc ggctccagca ggtcggtcca gatccagtgc gcgaaggtga
    10501 gccggcgcag ttcgaggtac tcctcgacgc cgggcacgat tccgcgggtg cggttgtgga
    10561 attcacggtc gtacgcctcg atcaccgcgt ggaagtgccg ggcgaaccgg gcgttccagg
    10621 tggcgggcag gaaggcgtag agccgccgca cactgtcggc gaacccggcc accagggtgt
    10681 cctcgtggtg caggtggtca ccgggtgagt cgagtgccgt gtgcagccgg gcgcgcagcc
    10741 gccgccaggc gccgggacga ccgtggacga tgtcacggtc gtgccggtcg tcccagacga
    10801 agaaccacgc gctgtagtcc gctatcgcct gcatgacctc gtcgggggcg cccaggtagt
    10861 agcccgccat gaggtccgtg tagcacaggc cgtcggcata ttcctcgacc ttgtccgccg
    10921 gcatgagccg cttttcgagc agccaggcgc gggtggcctc ctggagcctg ggccaatacg
    10981 gatgcagttg ccggggaaat gccgcctcga tcaccggaag acgaagcgat gacggtactg
    11041 cgatcgcggt cggtgtcgct gtggtgccgt gtgagaaagc atgcacgaac aaacccctct
    11101 cagccgccgg tggcgcaccc ctctccctga gcggggcgtg cgccgttgcg tatccccgca
    11161 cttcccattc agcaccacaa ctgaccgttc tgggaacgga tttgcttcat tcactacccc
    11221 ccggtgccgg aattctcctg ttgtgtggcg gctttccatg cgcgtgcaca gacgaacggc
    11281 gcccgctcgg ggaagacccg aacaggcgcc gtacgcaagg gagatgtggg gcgggtgggg
    11341 cggtgtcagc cgttcgcgac cacggggtag cggggctcgt tctcggccat ctgccgcagc
    11401 gcgtccttgc gttcgcgctt ggagagccgg tcgatgtaca ggtacccgta caggtggtcc
    11461 gtctcgtgct gcaaacaccg ggcgaagtac ccggtgccgc gcaccttgac ggggttgccc
    11521 ttctcgtcct gcccggtcac ctcggcgtag tcggggcggg cgagcggtgc gtaggcggtc
    11581 ggcacggaca ggcagccctc gttgctgtcg tccaggcgac ggcggtcggc gggcagttcg
    11641 accagcttgg ggttgcagac gacgccgacg tggcggacgc cctcgtcgtc ggggcagtcg
    11701 tagacgaaga ccttcttgga gacgccgatc tggttggcgg ccaggccgac gccctcggcg
    11761 gtgcgctggc tggcgaacat gtcggccacc agctgctgga actcctcgcc gaagtccgtg
    11821 acgtcctcgc actccttgtg cagcaccggg ttgccgacca ccgtgatcgg gcgcgaggtg
    11881 ccgcgcccgc gccagtcggc ctcacgctcc tcgcagtcct gggtgtcgac gacgaacccc
    11941 tcgtcgtcca cggggagcac gccggggtgc tgctgatcgg tgtcctgctg ggccatgacc
    12001 gacgtatgcc ttcctggatg aaacaggggt ggatgctgat acagggtacg gggagagcgc
    12061 ccctgaaagg ggcgcgggcc agtgccgata tgcggctccg ccgcgtgggc gcgaccagcc
    12121 acgacgtagc cgcagtcgag cagacgacct cagcagacct cttccaggtc ccgccagtca
    12181 cgcgagtccg gactgtcggc cacccacccg tccagcaacc ccttcaccag cccagccggc
    12241 gcagccactc cgcactcccg ctccggtacc cacagctgcc cgtcggtgcg gtgcccgagg
    12301 ggcccggggt gtccgggttc gctgtggtcg tgcgggtcga ggtgctcgcc ctcgccctcg
    12361 tcggacggca tccgggactc cgagcacatc cggcacagca gccggacgga ggaggaccag
    12421 tcctcggcgg cgaacccggc gtcggcggcc agctgctcca gggcgtcgcg gtcggcctcg
    12481 gtggcggcct ccaggaggac cacccaggtg ggcacgggcg acggcgccca cagctcgatc
    12541 tcgtcgaaga cggggtagga gtgcccggcg ctggtcgtcc gctccccgtg cggcacgccg
    12601 tcgtgcagga cgacctcgcc ccagcgccgg cccgaggagg gcagcgggat ggacagcacc
    12661 tcgacgcggg cggggtcgag ccgccgcccc cacaccacct cggcctcgcc ctccggggac
    12721 agccgtacgg ccgcgctgcc gaggtccatg ccgagcggct caccggcgtc cgtggcgtcc
    12781 cccggggtgc gcagcccgta ggcctgccag gcccggcggg ccagcggcca gtcctgcagg
    12841 gcggtcgcgg cgatgccgac gttccaccag tcgggcgcgc cggcgtcccg gtcgagcagc
    12901 gcgacggcgc gcagaccggc cgccctggcc tgctcccagt cgtgccggaa cttgtgcagc
    12961 agcgccaggt tgaaccagga ctccgacagc cagggctcca ggtccgccgc ccgcgtgagc
    13021 agcgcgcccg cgtcctcgta gcgaccgtcg ccgatcagcg tgaacgcgcg gtcggtggcc
    13081 tgccgccagg aggcggaggg ccggtgccgt gccttgccga agatcctcac gattcccgcc
    13141 tgccagttcc gttcagtggg ctggctgtgc ctttcgcgcc cccggacacc ctctcccggg
    13201 catcaaacca cgtacggctg cggaggcgct cattacccat gggttaccca gccgagggcc
    13261 cggtaaggct gccccgggaa aggacccggg ccagcgcttc caccacttcg ggagcgtagt
    13321 caccggcggt ggccagacgc agctcctcca gcgccgtcag cacacccccg gggcccgcgt
    13381 cccgcgcctt ctcctcgtag gcgttcacga cccggacgat gcgcgcggcg accggctgct
    13441 cccggcacgg gtcggcctgc cgctccacca ccaccgcgac cgccgcgtcg acgccggtct
    13501 ggcggacgac ggccccgccg agcagcgcga tccgccgctg ttcggtgacg ggcaggtccg
    13561 cggtggcgcc cgccgggacc gggtccacca ggctcagctg gccgatgtcg tgcatgaggg
    13621 ccgcgtactc cagcacggtc agctcggccc cggaaagccc caggtcccgc ccgacggcca
    13681 ccccgagtcc ggcgacgcgg cgggcgtgcc cggccggggt gtacccggcg atctcggtgg
    13741 cgcgggccag ggaggcgatg gtctgccggt aggtggcccg gacggccgcg taccggcggt
    13801 aggagagctg ggcgagcagc aggggcacac agaagacggg cagcgcccac agtcccgcga
    13861 cgctcaccgc gagcgccatc accgcgccgg tcgcgcacac cgcggaggtg atcccgacca
    13921 tgccgcgcag ctcttcgcgc aggaggggac cgaagggcca gccggtgcgc gcgtgcgcgg
    13981 gtgcggcggc gagcacggcg tcgcacagcg tggtcagggc gaggagcgcg atcaggagca
    14041 gcgcgtaggc gggaccgctc cagtagtcga agacgccctg gttggacagc ggccggaagc
    14101 acaccgcggc gaacgcgacg gtcagtacgc gccgcgccag gtggtcgagg acggggccgc
    14161 tgccgcgggc gacgtagggc acgctgccca gcagtgaggc ggcgagcacg acggtgacgg
    14221 tctgcgcgac accgtggtgc gcgggctgcc cggcgacgtc tccgagcagc gcgtacgcca
    14281 gcgcgcccgc ggccccgagc ggcgccgcct cccgggcctc ggtgccggtc cgccgggtca
    14341 gctcgccgag ggcgacgagg cccccgaaag cgagcgccac gggccgctgc acgggccccg
    14401 agaccagtac ggaggccaga cacccgagcg cgaggagccc ggcacagccg ggtacgagga
    14461 gcagcgccac cgacggcggg gactgggccg gtggcggcga gggcgtcatg gcgcgcccct
    14521 gccgacgctg tccctcgcgc cctcgccgcg gcccggggac ggggcggcgg ggagtgtggg
    14581 agtgccgtcc gccgtcaccg acgggcgcca gccgtggcgg ccgagggcac ggaccagcgc
    14641 ccgcaccatc cgcggatcga actgcgcccc ggcgcaccgc tggagctcct ggagcgccac
    14701 cgcgacggga cgggctctgc tgtaggagcg cgtggaggtc atcgcgtcga aggcgtcggc
    14761 cacggccacc acccgggccg actcggggat ccggtcgccg gccagtccgt aggggtagcc
    14821 gctgccgtcc agccgttcgt ggtggtggag gacggcggcg cgggcctctc cgaggaagcg
    14881 gatgccgcgc accatctcgt gcccgtactc ggggtgcagt tcgatcaccc gccgctcctc
    14941 gggcgtcagc ggcccgtcct tgcgcaacag ccgggtgggg acgccgagct tgcccacgtc
    15001 gtgcaggatc ccggcgaagc ggagggtctc gacgcgttcg tcgtccatgc ccagctcgcg
    15061 ggcgatcatc atggaggcct ggccgacgcg ttcactgtgg ccgcgggtgt agccgtcctt
    15121 gatgtcgacg gcctgcacca gcgcccggat ggtcgcctgg tgcgcggccc gctcgcggtg
    15181 gtactgggcg aaggcccacc acgccacgca catcggcagc agcacgagca gcgcggccac
    15241 cggaccgtac gggctgcgcc acaggacggc catcatcagc ccggcgagcc cgtgcacggc
    15301 gatcggcgcg agcgaccggg agaacagccc gcgccaggcc cggctcggcg gcacccggtc
    15361 ggccagggtg aggatcccgc cgtccaggac ggtgagcacc aggcagaacg cgaggacggc
    15421 ggccccggcc ggcacgaggg cgtacgggaa ggcgggctcc acgaccgcgt cccggccgcc
    15481 gagccgccag tggacgcagg cggcggccca cacggcgagg gtcagctgcg cggcccgcca
    15541 cacgcgccgc aggccgaacg gccgccgggg caccggggac agcagggccc cgggcagcgc
    15601 cacgagcgcg gcggcgggcg gcggcagcag gaaggcaccg gcgagcagga cggggtagca
    15661 ggttcctacg aagcgggacc gcgcgaccag ctcggagccc gcgtacaccc cggccagcag
    15721 cagcaccgcc caccagggcg cgtgcaccga cggcaggggc cgcaggcaga gcacggcgac
    15781 gagggcgacg caaacgacgt acgcacgcgc gcgtgcgggt accgcgtcca tgagcccctc
    15841 cccggccacg cctgtaaggc tcggagccta gggcggcgaa ggggaggccg cgggcagata
    15901 acccgcggat tagcacgtac gagtgacgta cgggtgatgt acgaaggact cgcgacggct
    15961 ggagacggct caggactcct gcggtgccga aggtgtggcc gtgacgtcgt gctcgggcac
    16021 ggactgcccg gaccggatca ggtccagccg tcccatgacc ttggagcgca ggtcacccgg
    16081 cacgtcgtcc tggccgcagc accgcttgac cagcttcttc acggcctgct ccagcccgta
    16141 cttctccaga cagggcgagc actcctcgaa gtggtgctcg aacttcacgc agtccgagtc
    16201 cggcatctct ttgtcgagga actcgtagag atgatcgagg atttcgctgc aatccgtctc
    16261 gtgcggctct ccgcagctca tgaccccgag cctttcgctt cgttcgactc tccggcgccg
    16321 gcggggacca gaccgcggtc gcgggcgtag tcctccagca tgccgcgcag ctgacggcgt
    16381 ccacggtgca gccgggacat caccgtaccg atgggtgtcc ccatgatgtc cgcgatctcc
    16441 ttgtaggcaa agccctcgac gtccgccaga tacacggcga tacggaattc ctcggggatc
    16501 gcctggagcg cctgcttcac gtccgagtcg ggcaggtggt cgagcgcctg cgactccgcg
    16561 gagcgcagac ccgtcgacat gtgcgactcg gcacgcgcga gctgccagtc ctcgatctcc
    16621 tcggccgcgc tgcgctgggg ttcgcgctgc ttcttgcggt acgagttgat gaaggtgttg
    16681 gtgaggatgc ggtacagcca tgccttgagg ttggtgccct cgcggaactg gtggaaggac
    16741 gcgtacgcct tggcgtaggt ctcctgcacc aggtcctcgg cgtcggccgg attacgcgtc
    16801 atgcgcagcg cggccgagta catctggtcg aggaactcca gcgcgtcccg ctcgaagcgc
    16861 gcactgcgct cggcggccga ctccgcgccc gtaccccggc cctcgggctg ctccgcctgg
    16921 ccgtgttcgg tccctgcgtc ggtcccagtg accggaccca cctcctccag tgttgtcgtg
    16981 aaaccgagag cggcctcact cgaatcggag gatagacgac gatccggtcc gcccgccgcc
    17041 cgaatagggg cggtcttggc agcgtgcagc acggtccagt ccaggtcggc gcggctgctg
    17101 cgactcgggc agaaggctga acccatgcgg cggacttcct ctcctacggc gtcggtgctg
    17161 attctcagca acgtatgcac cgcacaacag cggccgtgcg ccggtcattc ccgggcgttc
    17221 agccgagtga gccggtccac ttcaggacgc cgtcggtgat cagctccagc gcccgttcct
    17281 gactgatccc ggcccgcttc ggcacggcga agccgtggtc gccgtacggc acctcgacca
    17341 ggtcgtaggt gccctcgggc gccgccggga actccgccgg cctgccgaag gggtcgttgc
    17401 cgccctggac gacgagggtg ggcaccccgg ccccgagcag ctcggctgcg cgggacttct
    17461 ccggcttgcc cggcggatgc aggggaaagc tgagggcgag cacggcgtgg gcgcccagtt
    17521 cggccgcggt gcggcaggcg acccgggctc ctgcgctacg gccgcccgag atcaccggca
    17581 ggccgggcgc ggcgagcgcg ggccagacac cccgccagcc ggtgtccagg gtcttcggcg
    17641 cgggcgccag cttcttgccg gccacccgcc agggctgctc cacgagggcg acgctcactc
    17701 cgtgggcggg cagagcgccg gccagggctc gcaggtcgcg tgcctcgatg ccgccgccgg
    17761 cgccgtggct cacggcgagg acgagccggg gccgcctcgc ccagtgccag gtgatgcggg
    17821 cggggcccgc gtccgtctcg accgcctctg tcacaacctc tgtcgcatcc gtcacgtcag
    17881 aagagtgtgc cctcttccgg tgcctccagc tccttgagca gctccggccc gttgttgcgg
    17941 acgttgctca cggccgtcga gacggggaag gcccgcatca gaccggtggg cggcggcgcc
    18001 aggagggagg tcagctcgtc ggggtcggtg cgggccgggt cgagccagtc gtcccagcgg
    18061 tccggggtca gcatcagcgg catccggggg tggatgtcgg ccagggcgtg cgggccgtcg
    18121 gccggggcca cggcgagcgg cgcggtctcg gcctcggtgg tgatcaccga gcacgtcacc
    18181 caccaggcct gcgggtggtc gtcgggaagg gtccggtccc gccagaactc gtagagcccg
    18241 gccatggcga acacggagcc gtcggcgggc gtgacgaagt acggctgctt gcggggccgc
    18301 ttcttgcgcc cctcgacctc caggtcccgc tcctgcttgc cggtgaccca ctcgtagtag
    18361 ccgtcggcgg gcaggatgca gcgccgggtg ctgaaggcac ggcggtagga gggcttctcg
    18421 tggacggtct ccgcgcgggc gttgatcatc cgggcgccgc cctcgggcgt cttggaccag
    18481 gagggaacca ggccccactt cagcttccgc agctggcgaa ccggcttcgg gtcctcgacg
    18541 tctttcagag gacggtccag gaccgcgtag acctccttgg tgggggccac gttgtagtcg
    18601 ggctccaagc tctccttggg ctcccacttc tcgatctcga agattcccgc gagatcctcg
    18661 ggccggcgac tcgccgcata ccgtccgcac atacgtgcca cactgccaga ccccgcgttt
    18721 ctacgaggag ccctccccga acatggacca cctcgcaacg gcctcgctca cctccctgtg
    18781 ggacgaggtc tccggcaccc agcccgatcc cgacctgtgg gtggtgatcg cgaccctggt
    18841 ggccgcgctc gccgtcgtcc tgacgcgcgg gtcgtggcgg atagcgcgca acgcgatcac
    18901 catcgcccac gagggcggtc acggactggt ggccctgctg accgggcgca ccctgaccgg
    18961 gatcaccctg cactcggaca ccagcggcct gaccgtgagc cggggcaagc cgcacggcct
    19021 cgggatgatc ctcaccgccg tcgcgggcta caccgctccc ccgctcctcg ggctcggtgg
    19081 cgccgcgctg ctggcggcgg ggcgcatcac gctgctgctg tggctggcga cggcgctgct
    19141 cgtggccctg ctggtgatgg tccgcaacgc ctacggggtg ctgacggtgg tggtcaccgg
    19201 cggcacgttc gtcctggtgt cctggctggc cgggccgcag gtgcaggcgg cattcgcgta
    19261 cgcggtggtc tggttcctgc tgctcggcgg ggtgcgcccg gcgttcgagc tgcaggccaa
    19321 gcgggcgcgg ggcggagccg gggactcgga cgcggaccag ctggcgcgac tgacccacgc
    19381 gccggcgggg gtgtggttct tcctcttcca cgcggtgtcg ctgtgctcgc tgatcggcgg
    19441 cggacgctgg ttgctggaac tgtgaggtgc gcacctctga cggcgcccga ggggaaacct
    19501 ccccgcgacc gcagaggaaa cgtcccggcg accgcatata tgcacggcaa gtgcactgtc
    19561 gtggtttcgg tcaggtttcg ccgcttttga tcaagatctc cggccgtccc cagccattaa
    19621 agtggggccc atgaccgtga atcccgcgca caccgccctc tggcccgccc cgcacgcgag
    19681 cggagccgtc gacgcgaccg tccacgtgcc cgggtccaag tcggtcacca accgcgccct
    19741 ggtgctggcc gccctcgcct ccgagcccgg ctggctgcgc cgcccgctgc gctcccgcga
    19801 caccgtgctg atggccgagg cgctgcgcgc gatgggcgtc gagatcgagg agggcgtcgg
    19861 cccggacggc accggcgagt tctggcgggt catcccggcg ggcctgcgcg gcccggccac
    19921 ggtcgacgtc ggcaacgccg gcacggtgat gcgcttcctg ccgccggtcg ccacgctcgt
    19981 cgacggtccc gtccgcttcg acggcgaccc gcgttcgtac gagcgtccgc tgcacggcgt
    20041 gatcgacgcg ctgcgcgtgc tgggcgcccg gatcgacgac gacgggcggg gctccctgcc
    20101 gctgaccgtg cagggcggcg gcgccctgga gggcggtccg gtcgagatcg acgcgtcgtc
    20161 ctcctcgcag ttcgtcagcg ccctgctgct gtccgggccg cgcttcaacc agggcgtcga
    20221 ggtgcgccac accggctccg cgctgccgtc catgccgcac atccggatga ccgtcgacat
    20281 gctgcgcgcg gtcggcgccc aggtcgacac cccggagtcc ggcggcgagc cgaacgtgtg
    20341 gcgggtcacg tcgggcgccc tgctcggccg ggacctgacg atcgagccgg acctgtccaa
    20401 cgcccagccg ttcctggccg cggcgctggt gaccggcggc aaggtcctga tccccgactg
    20461 gccgtcccgc accacccagc ccggggaccg gctgcgcgag atcttcaccg agatgggcgg
    20521 ctcctgcgaa ctgacggact tcgggctcgt gttcacggga tcgggcacga tccacggcat
    20581 cgacgtcgac ctcggcgagg tcggcgagct gaccccgggc atcgcggccg tcgccgccct
    20641 ggcggactcc ccctcgacgc tgcggggcgt ggcccatctg cggctgcacg agacggaccg
    20701 gctggccgcg ctcaccaagg agatcaacga actcggcggt gacgtcaccg agaccgccga
    20761 cggcctgcac atccgcccgc gccggctgca cggcggcgtg ttccatacct acgaggacca
    20821 ccgcatggcc accgccggcg ccgtcatcgg cctcgcggtc gagggcgtgc agatcgagaa
    20881 cgtggcgacc accgccaaga ccctgcccga cttccccgac ctgtggaccg ggatgctcgg
    20941 ggcgtaggga cggttcgcca tgcgccgcta cggcaagcac accgacgagg acgacatccg
    21001 cacccgcccg aaccgcaagg gcaaccggcc gcgcacccac atccgaccca agcacgagga
    21061 cgccgcggcg ggcctggtcc tgacgg
//
