LOCUS       NZ_CP085300            27785 bp    DNA     linear   CON 18-JAN-2024
DEFINITION  Streptomyces sp. BSE6.1 chromosome, complete genome.
ACCESSION   NZ_CP085300
VERSION     NZ_CP085300.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. BSE6.1
  ORGANISM  Streptomyces sp. BSE6.1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8024389)
  AUTHORS   Ramesh,C., Anwesh,M., Vinithkumar,N.V., Kirubagaran,R. and
            Dufosse,L.
  TITLE     Complete Genome Analysis of Undecylprodigiosin Pigment
            Biosynthesizing Marine Streptomyces Species Displaying Potential
            Bioactive Applications
  JOURNAL   Microorganisms 9 (11), 2249 (2021)
   PUBMED   34835376
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8024389)
  AUTHORS   Chatragadda,R. and Maile,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2021) Andaman and Nicobar Centre for Ocean Science
            and Technology, National Institute of Ocean Technology, Dollygunj,
            Port Blair, Andaman and Nicobar Islands 744103, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-OCT-2021
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/18/2024 07:10:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,273
            CDSs (total)                      :: 7,198
            Genes (coding)                    :: 7,094
            CDSs (with protein)               :: 7,094
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 47 of 104
            Pseudo Genes (incomplete)         :: 80 of 104
            Pseudo Genes (internal stop)      :: 9 of 104
            Pseudo Genes (multiple problems)  :: 30 of 104
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:03:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1702187
            Orig. end                         :: 1729972
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP085300.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of Ocean
            Technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27785
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="10"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..27785
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..27785
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:17785]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..17785
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     misc_feature    77..92
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.91"
                     /tool="antismash"
     gene            complement(332..1441)
                     /locus_tag="LJA35_RS07485"
     CDS             complement(332..1441)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326068.1"
                     /locus_tag="LJA35_RS07485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="WP_233645337.1"
                     /transl_table=11
                     /translation="MSRADDQPLPPAPPASPGRRLLLKGAAAAGALAAVPTVASAAPTV
                     PAAAPAKAAPYANPLVRNRADPHIRRHTDGFYYFTATVPEYDRIVLRRSRTLGGLATAG
                     ESVVWRKHATGDMGAHIWAPEMHRVDGKWYIYFAAAPAERVWDIRIWVLENAHADPFRG
                     TWVERGQVRTAWETFSLDATTFTHRGTRYLAWAQHEPGMDNNTALWLSEMANPWTLTGP
                     QVRLSTPEYDWECVGFKVNEGASVIARNGRLFMTYSAAATDANYCMGLLTVDADADLMN
                     PANWSKSPTPVFTSNDTTGQYGPGHNCFTVAQDGRTDVLVYHARQYKEIQGDPLDDPNR
                     HTRVQKLGWKADGTPDFGVPVPDSAGGRN"
     misc_feature    complement(1491..1505)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(1578..2237)
                     /locus_tag="LJA35_RS07490"
     CDS             complement(1578..2237)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972782.1"
                     /locus_tag="LJA35_RS07490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_102932068.1"
                     /transl_table=11
                     /translation="MSAPVRVVICDDQALIRTGLTTIVDAQPDLEVVGECGDGRTGVDL
                     ARELRPDVVVMDIRMPVLDGLEATRLLAGAGVEHPVKVLVVTTFNLDEYVYEALRAGAS
                     GFLLKDAPPDRLLHGIRTVAMGAALLDPDVTRRLVGRYAARIRPAEGTTRDIPLTPREM
                     EVLRLIADGLSNSEIAATLVISPETVKTFVSRILTKLDLRDRVQAVVFAYRHGLVT"
     gene            complement(2234..3391)
                     /locus_tag="LJA35_RS07495"
     CDS             complement(2234..3391)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972783.1"
                     /locus_tag="LJA35_RS07495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine kinase"
                     /protein_id="WP_165286483.1"
                     /transl_table=11
                     /translation="MIDRRRVLELWRRLDVTVRDLPLGVLLLVASLLPQLRGQGTEIGG
                     LPTRPADALAGVAAVLQSIPLAVRRRWTLVCLALVSLGFALDQLRGYHLFAGAALPIVL
                     ISAGSHQEKYRRATQVVATLAYVAMAVGLKARGGDETLVEYVTFYLVLALAWGIGAWMR
                     SGRAAEAERRARVAEDARNAERTRIARELHDVVTHHVTAMVVQSEAARYLTAAPDRLDE
                     TLAAVSDTGRRAITDLRHLLDLLNPDHGTAEPRTPPVGRVLTLVEQTRRAGQPVEFTEE
                     GTPAAATGSSDLVAYRVVQEALTNALKYDHGARTSVLVRHGEREITVEVGTDGSGTGAA
                     SPGGSGRGLAGLRERVDVLGGEFSTDRPADGGFVVRARIPGGSTA"
     gene            complement(3388..4230)
                     /locus_tag="LJA35_RS07500"
     CDS             complement(3388..4230)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0071586 - CAAX-box protein processing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972784.1"
                     /locus_tag="LJA35_RS07500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type II CAAX endopeptidase family protein"
                     /protein_id="WP_164412354.1"
                     /sec_met_domain="Abi (E-value: 3.6e-11, bitscore: 42.0,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFVWQFLAVLAAYAIGGAAIQAVKDNDWLTLVVGLTAAALVLFV
                     YGWVVRRTERRQALDVALEGAGAKFGWGTLIGAGMFSAVIVNLFTSGHYEVDGLGSVQG
                     AIGLVGFMAGAAATEEVVYRGVLFRIIEEHIGTYLALGLTGLVFGLSHLLNEDATLWGA
                     VAIAIEAGFMLAAAYAATRNLWLTIGVHFGWNFAAGGVFSTVVSGNGDSEGLLDATMSG
                     PKLLTGGDFGPEGSVYSVGFGVLLTLVFLWLAHRRGNVVPFGARRRAAGADSAVTLPR"
     gene            4395..5339
                     /gene="mmuM"
                     /locus_tag="LJA35_RS07505"
     CDS             4395..5339
                     /EC_number="2.1.1.10"
                     /GO_function="GO:0047150 - betaine-homocysteine
                     S-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mmuM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385562.1"
                     /locus_tag="LJA35_RS07505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="homocysteine S-methyltransferase"
                     /protein_id="WP_233645338.1"
                     /transl_table=11
                     /translation="MTSDFADDSPDGACVRSFADALAAGPLVLDGGLSNQLEAAGHDLG
                     DALWSARLLADDPEAITRAHLAYFEAGADVVITSSYQATFEGFARHGIGRERAGELLAL
                     SVESAKEAARRAHASRPLWVAASAGPYGAMLADGSEYRGRYGLDVAELERFHRPRLEVL
                     AAARPDVLALETVPDTDEAVALLRAVRGLGVPAWLSYTVDGDRTRAGQPLEEAFALAAE
                     AEEVVAVGVNCCAPGDVSGAVRTAARVTGKPVVAYPNSGEVWDARARAWRGRSLFAPRL
                     VREWRAAGARLVGGCCRVGPDAIRSIASGPSSS"
     gene            complement(5341..6210)
                     /locus_tag="LJA35_RS07510"
     CDS             complement(5341..6210)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445398.1"
                     /locus_tag="LJA35_RS07510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6282 family protein"
                     /protein_id="WP_233645339.1"
                     /transl_table=11
                     /translation="MTAADGGARTARFIDVHYHCGPDAYVRRRTATTAAAAYAEHGGWV
                     VLKNHLGSTAAQAWEARQQGLPVSGSVVLNDLAGGFDPRAVEQAVVQHGEDSGLRLIVH
                     LPTVTGRAHRSRLTRTPSHPLLADGQRPLTVTDDSGRLRPDVRELLRAARDLPVVVSTG
                     HADGHEVRLLIEEAVRLDLPRLMLNQPANPMTGLTCKDLADLVGAEQVFTEQTALTHLL
                     GYQPWNDLADVLTLLPRVVYSSDLGQPSQPDITDWLTRSAEWFDRAGLTPRRVREITRD
                     APLAMLSL"
     gene            complement(6197..6910)
                     /locus_tag="LJA35_RS07515"
     CDS             complement(6197..6910)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445397.1"
                     /locus_tag="LJA35_RS07515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RraA family protein"
                     /protein_id="WP_165286487.1"
                     /transl_table=11
                     /translation="MTTATAPSGDTGELRRRLARLDTAALSDAMDSLRTPPCVLPGIRP
                     RTPGTLACGPAFTVRYRPLDADARGFRNAADYIDEVPAGSVVVVDNGGSLTCTNWGSLL
                     SSVALHRGVSGTVVHGSVRDVAESRAAGYPLFSTGVTMVSGKNRVVLDRTGVSVDIGGT
                     TVDPGDWIVADDNGALRVPAALAAEVLRRAEAVDRTEARIRAAVLDGGRLDGARARFGY
                     ARPWEDEDGGRHDGR"
     gene            complement(6907..9120)
                     /locus_tag="LJA35_RS07520"
     CDS             complement(6907..9120)
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012407.4"
                     /locus_tag="LJA35_RS07520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isocitrate/isopropylmalate family dehydrogenase"
                     /protein_id="WP_165286488.1"
                     /transl_table=11
                     /translation="MNRKTVAVLPGDGIGPEVLDAALPVIDALDLPLDLEFGDIGWECW
                     RAEGNPVPDRTWNLIDRSDAVLLGATTTKPRGEALAELAPELRASAPRYISPIIQLRRR
                     LDLFANLRPVENYLGGTTPYRYCVVRENTEGLYAGLDFSPVPDALWPLVADHPNVRRST
                     RTGAAASVRLQTAHGLDRILRFAFETARTHGYERVTLADKPNVLRDSSAYVLDRLERVA
                     GDYPEIPYEVLNVDAVALWMTRRPERFGVIVAENMFGDILSDLGGGVMGGLGLAPSANI
                     GESGNYFEPVHGSAPALAGRQRANPTAAFLTIGLMLDHLGFTEEAGAVKDAVRHVTRRR
                     DRVTYDLGGSATTAEAAEAVVDACRALPQAPTAAVVTVGDELLRGDLEDSNAGHASRML
                     AERGIPVRARHTVGDDEAGIADAVRSCLGRDDVVVVMGGLGPTSDDVTRGAVARALGRP
                     LEHREEAWQAVVARLTRFGVAVHDDNRRQALFAEGAELLPNPGGTAWGCRVESRGSTVL
                     MLPGPPRECLPMLEESLRDGLPHIPRPPETTTLFRRTLGVIEADAAALVDALVKEYGGP
                     ARTAYRWHYPYVDIRVTCPPEDAGDLARRLDATLARHVVTDRDRTAVQELAAVLDEHDV
                     VLDVDDRLTGGLFAAELARARGTGDGSRPLRVTLSGRWEGGDRTTYTGTVALNCAVHEG
                     TDERTDTLTVPNRGAEVTAYAAQYAAWTLTRHLTGHPHPEDPA"
     gene            complement(9117..10004)
                     /locus_tag="LJA35_RS07525"
     CDS             complement(9117..10004)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LJA35_RS07525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_233645340.1"
                     /transl_table=11
                     /translation="MTPPGPPSEPTHDAAPVPAHAVLGPAGSPRHAIVLAPVLARWDHG
                     AFFRRIAGPFLDSGHRVTIHDTLSLLRDGDDLGSLVHRWARYLAPGKDPGPAPGAPGQS
                     RHAPPDVLVGNALGGAVVQGMLGEEWTHRAKVLLLSGPTVADHRLNTTLERIAATADAE
                     GLPAATRLLEDVVRGPDGPAGAAHRRPTAPDAPAPTASARPTAADEPAARRLAAGLRLL
                     HDADARHPVRDFPGPLLHVYGERSRLVGREHLATGPLPHHRLVAVPRAGMRPHADRPDL
                     VRHTLTRFLGAELT"
     gene            complement(10001..10933)
                     /locus_tag="LJA35_RS07530"
     CDS             complement(10001..10933)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012885.4"
                     /locus_tag="LJA35_RS07530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_233645341.1"
                     /sec_met_domain="HMGL-like (E-value: 2e-33, bitscore:
                     114.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVINLDVTLRDGGYRNNFDFPLDYARHHVRESVAAGMEWIEIGYR
                     NGSFKPRPDIGRTGLGADDYIRALAEVVPPEHLCMIVHPKNITEDDLPRMYEAGARMVR
                     FCLPSGAPEAGLALLARAVDLGFATTVNITRVSQLDGRRLAELAAMSGDSGADVVYLAD
                     SNGSMLPREVSRLVTLVRSVTDAAIGLHAHNNLGLALANAIAAVEAGATWIDSSVLGMG
                     KGPGNLVTEQWLAYLGRRGSTEGHDLGRILALAHRMEGEFAEAAPSLPLPDLVLGHFDL
                     SVEERAKLPQGRISDAFSAARELTATGAR"
     misc_feature    complement(10919..10934)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.76"
                     /tool="antismash"
     misc_feature    10924..10938
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.28"
                     /tool="antismash"
     misc_feature    complement(11003..11018)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.54"
                     /tool="antismash"
     misc_feature    complement(11178..11187)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.02"
                     /tool="antismash"
     gene            complement(11185..12096)
                     /locus_tag="LJA35_RS07535"
     CDS             complement(11185..12096)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018531691.1"
                     /locus_tag="LJA35_RS07535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_165288647.1"
                     /transl_table=11
                     /translation="MELRQIQYFVAVAEDLHFGRAAERLHIGQPAVSQQVRRLERELSA
                     ELFDRSGRTVTLTPAGRALLPEGREVLRAMDSFAATARRLAAQGDATFRVGISSALGQR
                     LDDFLDALPDRGAGTRFEFQTLDAHTRLEEVRAGRLDAAFVRGLESAPGLLLLSLWQDP
                     LVVALPAAHELAGRDRLRLADLARLPLRIAPRAENPVLFDTVVLACRKAGFEPALGPPS
                     TGLQETLAEIGAGAAGWIPMYPAAAGTVSSRRVAVLPIDGEPVAIRMSLALRADADPER
                     LRLLTETSARVREKSAGKEPSA"
     gene            complement(12301..13668)
                     /locus_tag="LJA35_RS07540"
     CDS             complement(12301..13668)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387913.1"
                     /locus_tag="LJA35_RS07540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug effflux MFS transporter"
                     /protein_id="WP_233645342.1"
                     /transl_table=11
                     /translation="MRTASTPVPRPARTSYALLLAVLCSLNAGGLFASDINLPGVPDTA
                     QAFDAPVASVQWTFSAFMIGIAVSQAVYGPISDAYGRKPVIVFGLGLFVAASLVCAVAP
                     TIEVFGAGRLLQALGAGAGMVLGRAVISDLYEEKEAARTFATVMPIVGVSPSVAPLIGG
                     YLTSYVSWRAPFAVTALIGLTTLVVMVARIPESLPPQRRSKHLGATLKGYPGLLTRPRF
                     WAYTINLAVAYGGYFGYLAASPLVFQKMGLATETTSYCYITVSVAYVAGNLTSRSLVRR
                     RRIDELLWVGHGFFLAGALLMLGLGLSGAGGRWGLLVLVFMPVMTFGNGFLLPLSMSAG
                     VTAFRTTAGSASGLMGALQLLGASLGIYLTSRLPAGDLLALGWFVLAASAVGVVLFALF
                     LWLASRRRATGKPGSDAAATVAAAATAETAAPVATTATVATDAGGRPKEVQEAVAE"
     gene            complement(13751..13948)
                     /locus_tag="LJA35_RS07545"
     CDS             complement(13751..13948)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387912.1"
                     /locus_tag="LJA35_RS07545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4-oxalocrotonate tautomerase family protein"
                     /protein_id="WP_165288649.1"
                     /transl_table=11
                     /translation="MPLIHVQQTPGRTPEQKSELVRALTDAYVSATGSKPESVWVTVQE
                     IATDSWSIGGDTLAARAARS"
     misc_feature    complement(14082..14096)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     misc_feature    complement(14083..14096)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.07"
                     /tool="antismash"
     gene            complement(14147..15037)
                     /locus_tag="LJA35_RS07550"
     CDS             complement(14147..15037)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016645137.1"
                     /locus_tag="LJA35_RS07550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_125628243.1"
                     /transl_table=11
                     /translation="MTLPNHLYAQRMNVELRHLRCFLAVAEEGGFTAAAHRLHLAQPTL
                     TRNIRTLEESLGVRLFERTTRRTELTGKGEALREAVVPLLRQLDSALTDLRNGDRLRVG
                     FSWGLPEGLSRLAARFTEATGTGVEFIRCDTPRAGLDTGRADVALLRSTPLPKGLRGVL
                     LYEEPRSAAVPAGWKLAERSELDWAELAGLPLIVNIVSGTTFPDMWPAGSRPVVGSECR
                     NFDEWLEQVAVGLGVGTAPVSAARRYTHPSVRIMPLTGAPTVPAYLTYPSHGAHPQAAR
                     FADHAWRAAEELQPA"
     misc_feature    complement(15029..15031)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    15357..15372
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.69"
                     /tool="antismash"
     gene            15375..16193
                     /locus_tag="LJA35_RS07555"
     CDS             15375..16193
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (23-130). E-value:
                     3.4e-14. Score: 45.0. Matches aSDomain:
                     nrpspksdomains_LJA35_RS07555_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="LJA35_RS07555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_233645343.1"
                     /sec_met_domain="PF00561 (E-value: 3.2e-11, bitscore: 42.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.1e-12, bitscore:
                     46.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVITMRNGPLEHVVIDGDPDLSPLVFLHGGLGCLAAWGRFPARL
                     AAATGRRALVYSRHGHGGSGPDPLPRTVRYMHEHAHEVLPELLDALGMRRPVLVGHSDG
                     ASMALLHASAHPVRAVVGMGPHLYFEEENRRGIENARASYAAGPLARKLAMVHDDPRGV
                     FDRWSGVWLSPAFRDWSIEDELDVSAPVLAIQGDADEYGTLAQVDAVERAVHGPFVRLV
                     PEGCDHYPHLVRPGLVVDAVRAFLADPAAPSAHTGHTAHTDRIPSAGAGR"
     aSDomain        15444..15764
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LJA35_RS07555_Abhydrolase_1.1"
                     /evalue="3.40E-14"
                     /label="LJA35_RS07555_Abhydrolase_1.1"
                     /locus_tag="LJA35_RS07555"
                     /protein_end="130"
                     /protein_start="23"
                     /score="45.0"
                     /tool="antismash"
                     /translation="PLVFLHGGLGCLAAWGRFPARLAAATGRRALVYSRHGHGGSGPDP
                     LPRTVRYMHEHAHEVLPELLDALGMRRPVLVGHSDGASMALLHASAHPVRAVVGMGPHL
                     YFE"
     gene            16190..17785
                     /locus_tag="LJA35_RS07560"
     CDS             16190..17785
                     /NRPS_PKS="Domain: AMP-binding (13-427). E-value: 3.8e-90.
                     Score: 294.3. Matches aSDomain:
                     nrpspksdomains_LJA35_RS07560_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01733.1"
                     /locus_tag="LJA35_RS07560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_233645344.1"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-94, bitscore:
                     315.3, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTAPRLDALLARAARDHPGRTALEGAGESWTYARLERAVDAL
                     AARLSATGVAPGDRIGVHAPKSPATVVALYAVLRAGAVAAPLDTADPPERTARMIRNAG
                     LSALLTVDRTLTGARRAVARARDGRRRDDAPATAEALDHGLHLLRCLGPDERPAPLPPP
                     ADRGGYILFTSGSTGWPKGVLLSHENVAHYALWAAREFGLTPEDRIGSQAALTFDLTTF
                     DLFSAAAAGACTVLMPDPLRVFPRDVVAWLTEQRVTAFMAVPSLYHAMLQQGGVADAPP
                     ATLRIAAFGGEPFAPELLERYLRLFTGVPFYNLYGPTETNACTYYRVPADWTAGRELPI
                     GRGIGGVHVDVLDDEGRPTDGEGEIHIAGPVVFQGYLRGGAPEDPTVTAVFRDGVARRA
                     YASGDLGRMRPDGQVLLRGRRDHQVKRRGHRIDLMDVENAVLELAQVGTAAVVAREGAR
                     GPDGSRTVEIWAYAQTDATEHEVLAALRAVLPKRMLPDRVVPLTTLPTTTSGKVDRRAL
                     SGTAGPAHPEDVNV"
     aSDomain        16229..17470
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LJA35_RS07560_AMP-binding.1"
                     /evalue="3.80E-90"
                     /label="LJA35_RS07560_AMP-binding.1"
                     /locus_tag="LJA35_RS07560"
                     /protein_end="427"
                     /protein_start="13"
                     /score="294.3"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ARAARDHPGRTALEGAGESWTYARLERAVDALAARLSATGVAPGD
                     RIGVHAPKSPATVVALYAVLRAGAVAAPLDTADPPERTARMIRNAGLSALLTVDRTLTG
                     ARRAVARARDGRRRDDAPATAEALDHGLHLLRCLGPDERPAPLPPPADRGGYILFTSGS
                     TGWPKGVLLSHENVAHYALWAAREFGLTPEDRIGSQAALTFDLTTFDLFSAAAAGACTV
                     LMPDPLRVFPRDVVAWLTEQRVTAFMAVPSLYHAMLQQGGVADAPPATLRIAAFGGEPF
                     APELLERYLRLFTGVPFYNLYGPTETNACTYYRVPADWTAGRELPIGRGIGGVHVDVLD
                     DEGRPTDGEGEIHIAGPVVFQGYLRGGAPEDPTVTAVFRDGVARRAYASGDLGRMRPDG
                     QVLLRGRRDHQVKRR"
     CDS_motif       16415..16453
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LJA35_RS07560_0001"
                     /evalue="9.30E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="LJA35_RS07560"
                     /protein_end="88"
                     /protein_start="75"
                     /score="9.7"
                     /tool="antismash"
                     /translation="AVLRAGAVAAPLD"
     CDS_motif       16694..16750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LJA35_RS07560_0002"
                     /evalue="2.40E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="LJA35_RS07560"
                     /protein_end="187"
                     /protein_start="168"
                     /score="26.2"
                     /tool="antismash"
                     /translation="YILFTSGSTGWPKGVLLSH"
     CDS_motif       17276..17323
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LJA35_RS07560_0003"
                     /evalue="2.50E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="LJA35_RS07560"
                     /protein_end="378"
                     /protein_start="362"
                     /score="13.5"
                     /tool="antismash"
                     /translation="GEIHIAGPVVFQGYLR"
     CDS_motif       17441..17500
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LJA35_RS07560_0004"
                     /evalue="5.50E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="LJA35_RS07560"
                     /protein_end="437"
                     /protein_start="417"
                     /score="25.2"
                     /tool="antismash"
                     /translation="GRRDHQVKRRGHRIDLMDVE"
     gene            17782..18045
                     /locus_tag="LJA35_RS07565"
     CDS             17782..18045
                     /NRPS_PKS="Domain: PP-binding (19-74). E-value: 3.4e-11.
                     Score: 35.3. Matches aSDomain:
                     nrpspksdomains_LJA35_RS07565_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="LJA35_RS07565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_233645345.1"
                     /sec_met_domain="PP-binding (E-value: 1.7e-09, bitscore:
                     36.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSVEELCALIGSRITWGPGEDASSLTADTPLLEMGLVDSLAIME
                     IVAALDKEAGVTLPDTEIVAANFRSPKALWAAIEGLAVEGRP"
     aSDomain        17839..18003
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LJA35_RS07565_PP-binding.1"
                     /evalue="3.40E-11"
                     /label="LJA35_RS07565_PP-binding.1"
                     /locus_tag="LJA35_RS07565"
                     /protein_end="74"
                     /protein_start="19"
                     /score="35.3"
                     /tool="antismash"
                     /translation="GEDASSLTADTPLLEMGLVDSLAIMEIVAALDKEAGVTLPDTEIV
                     AANFRSPKAL"
     gene            18042..19202
                     /locus_tag="LJA35_RS07570"
     CDS             18042..19202
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933757.1"
                     /locus_tag="LJA35_RS07570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_233645346.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.8e-19, bitscore:
                     67.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.5e-19, bitscore:
                     67.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATPTAALRSCAPETEEIVDAYRDLAAPVTERAGDADFTARWRA
                     MADLGVLRLAPPDATAPGPVTRALAMIEGIGLAGVDPGLCYALASQVFGMQFPLRAALP
                     AAARDAVADVQDGRTLLCHALTERGGGSDPFSMETRAVRDADGFVLDGAKTFITAAPVA
                     DRAIVFARTAPGRSPFALSAFLLPLDLPGVRRGETFAKTALPTVPMGELIFEGARLPAD
                     ALLGEEGSGLAVMASTTAWERSVILGYALGPMHRLLTRTVEWAAGRDHFGRRMGASHQV
                     AARVSDMALALHRSRVQLYAMAARLDAGTPARQLAAQAALTKISVSEDYVRMTEHATAL
                     SGVRAFLPGFDLAADLSSPMAALTYAGPNDLLRVAVARQLGLPVEN"
     gene            19352..20539
                     /locus_tag="LJA35_RS07575"
     CDS             19352..20539
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.4"
                     /locus_tag="LJA35_RS07575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_233645347.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.5e-08, bitscore:
                     32.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.8e-16, bitscore:
                     57.8, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.4e-13, bitscore:
                     49.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLPTHFDDLLKLAADTGSAIAPLAAATDAADDDGHEAYRVLRES
                     GLLALLVPREAGGAGLGFGDYWRVLAELGAHHGAAALGFNMHHVVIGALAEAAGTRLSP
                     AADAFRTWMLGEVVDGRKMFASATSEAGRGAKLRGMRTRYRRSGDGTHYVLNGRKDFVS
                     LAGAADYYVVAAADGDDEESAEISHFVVAADDPGVGFGPVRHLSAMYGTSTAPMTLDEV
                     VVPRSRLYLGVEGMSLFKVVREPHWMFAGYTGAYLGMAQALYRHTVDRVTAAPGRADSP
                     VVQQELGRMSARLRAARALVHEAGDLVTAERGSLEANAMVHAAKYVVGETGPLLAQDAL
                     RLCGSAAVSRGHTLERLIREVQFAHVMPAKPHECLEYLGKAATGVNLYDARTFSW"
     gene            20536..21126
                     /locus_tag="LJA35_RS07580"
     CDS             20536..21126
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013756.4"
                     /locus_tag="LJA35_RS07580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavin reductase family protein"
                     /protein_id="WP_212731608.1"
                     /transl_table=11
                     /translation="MTPASTTASMPPAPRAGDERAVPHDAFRALMGSHPSGVAVVTTAD
                     ARGTPYGFTCTALCSVSLDPPQLLVCAAAGGSTLPVLAARGAFTVNLLHGSGRRAAQAF
                     AGPAAERFTTVPWRPGHLTGLPVLPQDSHATAECRVARTVPAGDHTIVIGEVLHTETHV
                     PAAEAAPLLYGMRRYASWPVRPGRTVPSVSPAP"
     gene            21137..21559
                     /gene="panD"
                     /locus_tag="LJA35_RS07585"
     CDS             21137..21559
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0015940 - pantothenate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954456.1"
                     /locus_tag="LJA35_RS07585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_087789120.1"
                     /transl_table=11
                     /translation="MYRTLMKSKIHRATVTQADLHYVGSVTVDSDLMHAAGLLPGEKVD
                     IVDIDNGARLSTYVIEGPAGTGVLGINGAAARLISPGDLVILIAYAAMTDEEAASFVPD
                     VVFVDEHNAVAGLGSDPAEVPAGSGLKRGDLVAEVS"
     gene            21556..22290
                     /locus_tag="LJA35_RS07590"
     CDS             21556..22290
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (4-156). E-value: 2.4e-18. Score:
                     58.6. Matches aSDomain:
                     nrpspksdomains_LJA35_RS07590_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433623.1"
                     /locus_tag="LJA35_RS07590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_233645348.1"
                     /sec_met_domain="adh_short (E-value: 4.1e-35, bitscore:
                     120.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLAVVSGGTRGIGRALSLRLAALGHRVVALYRGDDDAARQTEKA
                     GDGRIEALRCDLVRPEEVRAVCASLTARHGAPSVLVNNAGVNRDRPFLSMTDRDWDTVL
                     ATNLSGPFHLTRALAPAMVEAGGGSIVNVASTTAIRPRADGANYCASKAGLLQLTKCLA
                     LELAPHVRVNALLPGFTDTEEVTERYRLDDPERLGAVLDTIPRGRLGTAEDMADALEFL
                     VGARSGYVSGQQLVVDGGHFMG"
     CDS_motif       21568..21648
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LJA35_RS07590_0001"
                     /evalue="2.40E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="LJA35_RS07590"
                     /protein_end="31"
                     /protein_start="4"
                     /score="13.8"
                     /tool="antismash"
                     /translation="VVSGGTRGIGRALSLRLAALGHRVVAL"
     aSDomain        21568..22023
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LJA35_RS07590_PKS_KR.1"
                     /evalue="2.40E-18"
                     /label="LJA35_RS07590_PKS_KR.1"
                     /locus_tag="LJA35_RS07590"
                     /protein_end="156"
                     /protein_start="4"
                     /score="58.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVSGGTRGIGRALSLRLAALGHRVVALYRGDDDAARQTEKAGDGR
                     IEALRCDLVRPEEVRAVCASLTARHGAPSVLVNNAGVNRDRPFLSMTDRDWDTVLATNL
                     SGPFHLTRALAPAMVEAGGGSIVNVASTTAIRPRADGANYCASKAGLL"
     CDS_motif       21895..21948
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LJA35_RS07590_0002"
                     /evalue="1.30E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="LJA35_RS07590"
                     /protein_end="131"
                     /protein_start="113"
                     /score="1.8"
                     /tool="antismash"
                     /translation="LTRALAPAMVEAGGGSIV"
     gene            22335..23147
                     /locus_tag="LJA35_RS07595"
     CDS             22335..23147
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017532.4"
                     /locus_tag="LJA35_RS07595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytanoyl-CoA dioxygenase family protein"
                     /protein_id="WP_233645349.1"
                     /sec_met_domain="PhyH (E-value: 5.2e-35, bitscore: 120.3,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTQQQAAEYHERGFLMLESLLDAQEVETLRAAFERDAKVPGPQ
                     VVTEDGGTEVRAVYSSHQRQQEYAGLVRDPRILAPVRQLLCDDVYVYQFKINAKPPFGG
                     DKWAWHQDFLAWRIADGLPAPRQVNIGVFLDDVTEFNGPVIFLPGSHRRGLVREGRSAS
                     ARSEQHLDPDDISLSPGQLAEYVDRHGMTSPKGPAGSVVLFSPEIVHGSSPNMSPFARR
                     LLIATYNDAGNLPRPQGEPRPDYVVCRDTAPLRPLAAPFSQVPCAVAS"
     gene            23144..24268
                     /locus_tag="LJA35_RS07600"
     CDS             23144..24268
                     /NRPS_PKS="Domain: PKS_ER (140-305). E-value: 1.4e-11.
                     Score: 36.0. Matches aSDomain:
                     nrpspksdomains_LJA35_RS07600_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012335.4"
                     /locus_tag="LJA35_RS07600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_233645350.1"
                     /sec_met_domain="ADH_N (E-value: 1.8e-21, bitscore: 74.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.5e-18, bitscore:
                     63.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARAATAAATGRAVVLEEFGKPLALRTFPLPGPPAGGMVVACGY
                     GGVCGTDLHLCQGHLDIPVPLVLGHEGLGVVRELGAGTDRDAAGTPLAAGDTVMWASSI
                     SCGVCPPCRLHREPTLCERRRTYGVNRALADGPELSGAWADHIVLQPGTAVIKVPDGTD
                     PLAAMSLACAGPTVAHALFERRPVRLGETVVVQGSGPVGLAAAAFARLAGAAKVVIVGG
                     PAGRLERAADAGIGDVHLDIAGAGDPAEVLRQARAAVGGDGADLVIECAGVPAAVGQGL
                     GLARRGGSYLVIGQYTDAGDTTLNPHQIVHRQLDVVGSWAFTGAHLVEYVRLLPALTGR
                     FGLAGLVTPFPLERHADALDAVADGSVIKAVLTS"
     aSDomain        23564..24058
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LJA35_RS07600_PKS_ER.1"
                     /evalue="1.40E-11"
                     /label="LJA35_RS07600_PKS_ER.1"
                     /locus_tag="LJA35_RS07600"
                     /protein_end="305"
                     /protein_start="140"
                     /score="36.0"
                     /tool="antismash"
                     /translation="GAWADHIVLQPGTAVIKVPDGTDPLAAMSLACAGPTVAHALFERR
                     PVRLGETVVVQGSGPVGLAAAAFARLAGAAKVVIVGGPAGRLERAADAGIGDVHLDIAG
                     AGDPAEVLRQARAAVGGDGADLVIECAGVPAAVGQGLGLARRGGSYLVIGQYTDAGDTT
                     LN"
     CDS_motif       23711..23758
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LJA35_RS07600_0001"
                     /evalue="8.50E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="LJA35_RS07600"
                     /protein_end="205"
                     /protein_start="189"
                     /score="8.9"
                     /tool="antismash"
                     /translation="GETVVVQGSGPVGLAA"
     gene            complement(24327..25154)
                     /locus_tag="LJA35_RS07605"
     CDS             complement(24327..25154)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037627.4"
                     /locus_tag="LJA35_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_233645351.1"
                     /transl_table=11
                     /translation="MNGGGAGDPRRELGAFLRSRRERLGPADVGLPGSPRRRTPGLRRE
                     EVAELAGVSASWYAWLEQGRVRTSEQVLRSLARALRLNADETAHVLSFVERAAPDGPPP
                     GWVSPNLLSLVESLAPHPAAVLDPHWDLLAWNSGYSGLLTDLARLAPKQRNLLWLVFRW
                     PPARTLLASWESEARSLLGQFRAKAARHPQDGRYAEITGELLHDPDAARWYGRRETAAF
                     HPAVRHFRHPVAGDLHLRYVKLAAVDEPGHHLLAYLPDDRATAQGLELLAGQR"
     gene            25327..26562
                     /locus_tag="LJA35_RS07610"
     CDS             25327..26562
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387910.1"
                     /locus_tag="LJA35_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_233645352.1"
                     /transl_table=11
                     /translation="MDPADSSPTTSAPPPAGPGDPADPASARLATPMPAATLRLLRTAG
                     FVSNFDRFCITPMLLVIGTRLGVPLTTVMLAASGYFLAYGLMQPVWGLASDRLGRVRVM
                     RISLAGAAVAELASVLAPGATVLIVARVVAGACFAASIAASITYVGDTVPAAVRQRPLS
                     ELMTAFALGTAVATVVAGVLAHYASWRVVFALPGLIAAYLVVALRRLPEPPRAEPGALL
                     APFAVVLRSRWQWYVMAVALFEGAVLLGFLTYIAPALEAQGASAALAGAVTALYGVGSM
                     AAAQLVKRLVGRWTPVRLIVAGGVQMTVAFGCAAADRSVPALVVCALLLGGGWSFMHST
                     IQSWATALSPAARATGVAMFGVALYVGSALASTVAAGPAERHAYHGLFLTAAVLTVPLT
                     VAAAVGRARYRG"
     misc_feature    complement(26669..26684)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.1"
                     /tool="antismash"
     misc_feature    26670..26683
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.0"
                     /tool="antismash"
     gene            26715..27683
                     /locus_tag="LJA35_RS07615"
     CDS             26715..27683
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387909.1"
                     /locus_tag="LJA35_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4129 domain-containing protein"
                     /protein_id="WP_233645353.1"
                     /transl_table=11
                     /translation="MDRGGRTGHRAVPGAAVAVGVVGALALAALALRPAEGLLHSGRGP
                     LGQWGIVAIGASAAWTIGAWTAVRRLRPRFGANRMDLPPVEERLREIAAPLLLSATAVI
                     GVLALVLHRFSTGDGTPGPPPPLATEPAPEPTFATPPPQERPRGSGDHSALPLHLVLLA
                     LAAVVAVLVVVAVVRRLRRFRLSLPYRPGPSGSTAPQDDDARLLLSAVHSGRRALAGTD
                     DDARAAVIACYAAMEDALAASGVRRQASDSPADLLTRAAAAGFAPGPAGPRLTALFREA
                     RYSSHPMDGSHRAAAAAALEEIASLLGDPEPAPATDGKVER"
ORIGIN
        1 ggtgaccgtg gaggcgtgcc agtggtcggg ctgcgtcgcc tcccccgcca accgggcctc
       61 cagctccgcg aggtggtcga ccatgtggtc ggccacccgg cggatcgcct tgtgcggggt
      121 gtagaggcgg ccgtcgacgt gtgcgggccg tccgtcccag cgggtccagg tggcggccag
      181 ggcgaggacg tggtcgacca tgccggtgac ggcggcggcg ggggtcacgg cgggcgccgt
      241 gtgcgtgtgg ctcatgtccc gcacgctacg ggccactccc ttcggcgccg gccgaactgt
      301 gcccaccggt cgggcctctc cccggccccg ctcagttgcg ccctcccgcc gagtccggga
      361 ccgggacgcc gaagtccggg gtgccgtccg ccttccagcc gagcttctgg acgcgggtgt
      421 gccggttggg gtcgtcgagg gggtctccct ggatctcctt gtactggcgg gcgtggtaga
      481 cgaggacgtc ggtgcggccg tcctgggcga cggtgaagca gttgtggccg gggccgtact
      541 gaccggtggt gtcgttgctg gtgaagaccg gggtgggcga cttcgaccag ttcgcggggt
      601 tcatgaggtc ggcgtccgcg tccacggtca gcaggcccat gcagtagttg gcgtcggtgg
      661 cggcggccga gtacgtcatg aacaggcggc cgttccgggc gatgaccgac gcgccctcgt
      721 tgaccttgaa gccgacgcac tcccagtcgt actcgggcgt ggagagccgc acctgggggc
      781 ccgtcagcgt ccaggggttc gccatctcgg acagccagag ggcggtgttg ttgtccatgc
      841 cgggctcgtg ctgggcccag gcgaggtagc gggtgccgcg gtgggtgaag gtggtggcgt
      901 cgagggagaa ggtctcccag gccgtccgca cctgcccccg ctccacccag gtgccccgga
      961 aggggtcggc gtgcgcgttc tccaggaccc agatgcggat gtcccagacg cgctcggcgg
     1021 gcgcggcggc gaagtagatg taccacttgc cgtcgacgcg gtgcatctcc ggcgcccaga
     1081 tgtgcgcgcc catgtcgccg gtggcgtgct tgcgccagac gaccgactcg ccggcggtcg
     1141 cgaggccgcc cagggtgcgg gaacgccgca ggacgatgcg gtcgtactcg gggacggtgg
     1201 cggtgaagta gtagaagccg tcggtgtggc ggcggatgtg cgggtcggcg cggttgcgca
     1261 cgagcgggtt cgcgtaggga gccgccttcg cgggcgcggc ggcgggtacg gtgggcgcgg
     1321 cggacgccac ggtgggcacg gccgccaggg ctcccgcggc cgcggcgccc ttcaacagca
     1381 ggcgtcggcc ggggctcgcg ggtggggcgg gcgggagggg ctgatcgtcg gcgcggctca
     1441 tgcgggctgc ctctcgacag ggcgcacgac acgacccgtt cgccatgtcg aacgccatct
     1501 gtgattacga acgtcgaaaa ggtaagggtg tgccgtggag aggtcaacgg gtccgacgcc
     1561 gccacccgtg cgccgcgtca ggtcaccagc ccgtggcggt aggcgaagac gaccgcctgg
     1621 acgcggtcgc ggaggtcgag cttggtgagg atgcgggaga cgaaggtctt gacggtctcg
     1681 gggctgatca cgagggtggc ggcgatctcg ctgttggaga gcccgtccgc gatcaggcgc
     1741 aggacctcca tctcccgggg ggtgagcggt atgtcccggg tggtgccctc ggcggggcgg
     1801 atccgggccg cgtaccggcc cacgaggcgg cgggtcacgt cggggtcgag cagcgccgcg
     1861 cccatggcca cggtgcggat gccgtgcagc agccggtccg ggggcgcgtc cttgagcagg
     1921 aagccgctcg cgcccgcgcg cagcgcctcg tagacgtact cgtcgaggtt gaacgtggtg
     1981 accacgagca ccttgacggg gtgctccacc ccggcgccgg ccagcaggcg ggtggcttcg
     2041 aggccgtcga gcaccggcat gcggatgtcc atcaccacga cgtccggccg cagttcgcgg
     2101 gccaggtcga ccccggtccg cccgtccccg cactcgccga ccacctccag gtcgggctgg
     2161 gcgtcgacga tggtcgtcag accggtgcgg atcagtgcct ggtcgtcgca gatcacgacc
     2221 cggaccggcg cgctcatgcc gtgctccccc cgggtatccg ggcccggacg acgaagccgc
     2281 cgtccgccgg gcggtccgtg ctgaactcgc cgcccaggac gtcgacgcgt tcccgcaggc
     2341 cggccaggcc ccgcccgctg ccgccggggg acgcggcccc cgtgccggag ccgtccgtgc
     2401 ccacttccac cgtgatctct ctttctccgt gccgcaccag gacggaggtc ctggcgccgt
     2461 ggtcgtactt gagggcgttg gtcagggcct cctgcacgac gcggtaggcc acgaggtcgg
     2521 agctgccggt ggccgccgcc ggggtgccct cctcggtgaa ctccaccggc tgcccggccc
     2581 ggcgcgtctg ctcgaccagg gtgagcaccc ggccgacggg cggtgtcctg ggctcggcgg
     2641 tgccgtggtc gggattgagg aggtcgagca ggtgccgcag gtcggtgatg gcgcggcggc
     2701 cggtgtcgct gacggcggcc agggtctcgt cgagccggtc cggcgcggcg gtcaggtaac
     2761 gggccgcctc ggactggacg accatcgccg tcacgtgatg ggtcacgacg tcgtgcaact
     2821 cgcgggcaat acgggtgcgt tcggcgttgc gggcgtcctc ggcgacccgg gcgcggcgtt
     2881 cggcctccgc ggcgcgtccg gagcgcatcc aggcgccgat gccccaggcc agggcgagga
     2941 ccaggtagaa cgtcacgtac tcgaccagcg tttcgtcgcc gccgcgcgcc ttcagtccga
     3001 cggccatggc cacgtacgcc agggtggcga cgacctgcgt ggcacgccgg tacttctcct
     3061 ggtgggaccc cgcgctgatc agcacgatgg ggagcgcggc gcccgcgaac aggtggtagc
     3121 cgcgcagttg gtcgagggcg aagccgagcg agaccagggc gaggcagacg agggtccacc
     3181 gccggcgcac ggccagggga atggactgca ggacggccgc caccccggcc agcgcgtcgg
     3241 cgggacgggt cggcaggccg ccgatctccg tgccctgacc gcgcagctgg ggcaggagcg
     3301 aggcgacgag gagcagcacc ccgagcggga ggtcccggac cgtgacgtcc agccggcgcc
     3361 acagctccag gacccgtcgg cgatcgatca ccggggaagt gtaacggcgg agtcggcacc
     3421 cgcggcacgg cgccgggcac cgaacggcac gacgttcccg cgccggtgcg cgagccacag
     3481 gaacaccagc gtgagcagca ccccgaagcc caccgagtac acgctgccct ccgggccgaa
     3541 gtcgccgccg gtgagcagct tgggacccga catggtggcg tccagcaggc cctcgctgtc
     3601 gccgttgccg gagacgacgg tgctgaagac gccgcccgcg gcgaagttcc agccgaagtg
     3661 cacgccgatc gtcagccaca ggttgcgggt ggcggcgtag gcggcggcga gcatgaaccc
     3721 ggcctcgatg gcgatggcga cggcgcccca cagggtggcg tcctcgttga gcaggtgcga
     3781 gagcccgaac acgaggccgg tcaggcccag cgcgagatag gtgccgatgt gctcctcgat
     3841 gatccggaac agcaccccgc ggtagacgac ctcctccgtc gcggcggctc cggccatgaa
     3901 gccgaccagg ccgatcgcgc cctgcaccga gcccagtccg tcgacctcgt agtgcccgga
     3961 ggtgaagagg ttcacgatga ccgccgagaa catcccggca ccgatcagcg tcccccagcc
     4021 gaacttggcg ccggcgccct ccagggccac gtccagggcc tgccggcgct cggtccgccg
     4081 caccacccac ccgtacacga acagcaccag cgcggccgcc gtgagtccga cgaccagggt
     4141 gagccagtcg ttgtccttca ccgcctggat ggcggcgccg ccgatggcgt aggccgccag
     4201 tacggccagg aactgccaga caaacctcac gggaactcct tggtcgggcc cgtgacttgc
     4261 gcgcctcggg ctgtgacacg ggacgctacg gatccggcgg ccggagatcg tcacctcacg
     4321 gtggacacct ggctgtagct cgcacggggg acaaggcccc ggagcccggg cggccacgtc
     4381 gtagcctcgg acacatgacc agcgacttcg ccgacgactc ccccgacggc gcttgcgtcc
     4441 gctccttcgc cgacgccctc gccgcgggcc cgctcgtgct cgacggcggc ctgtccaacc
     4501 agttggaggc ggccgggcac gacctgggcg acgccctgtg gtcggcccgg ctgctcgccg
     4561 acgaccccga ggcgatcacg cgggcccatc tcgcctactt cgaggccggc gcggacgtgg
     4621 tgatcacgtc cagctaccag gccaccttcg agggcttcgc ccggcacggc atcgggcggg
     4681 agcgggccgg cgaactactc gcgctcagcg tggagtcggc gaaggaggcg gcccgtcggg
     4741 cgcacgcctc ccgtccgctg tgggtggcgg cgtcggcggg cccgtacggg gcgatgctcg
     4801 cggacggttc cgagtaccgg gggcggtacg gcctcgacgt ggccgagctg gagcgcttcc
     4861 accggccccg tctggaggtg ctggccgccg ctcggccgga cgtcctcgcg ctggagacgg
     4921 tcccggacac cgacgaggcg gtcgcgctgc tgcgggcggt gcgcggtctg ggcgtgcccg
     4981 cctggctgtc gtacaccgtc gacggggacc ggacgcgtgc gggccagccg ctggaggagg
     5041 ccttcgccct ggccgccgag gcggaggagg tggtcgcggt cggcgtcaac tgctgcgccc
     5101 ccggggacgt gtccggcgcg gtccggaccg ccgcccgggt caccgggaaa ccggtcgtcg
     5161 cctaccccaa cagcggggag gtctgggacg cgcgggcgcg ggcctggcgg gggcgttcgc
     5221 tgttcgcgcc ccggctggtg cgggagtggc gggcggccgg ggcccggctg gtcggggggt
     5281 gctgccgggt ggggcccgac gcgatcaggt cgatcgcgtc gggcccctcg tcgtcctgac
     5341 tcacagcgag agcatcgcca ggggcgcgtc ccgggtgatc tcccggacgc gtcgcggggt
     5401 caggccggcc cggtcgaacc actcggcgct ccgggtcagc cagtcggtga tgtccggctg
     5461 ggacggctgg ccgaggtcgg agctgtagac gaccctcggc agcagggtca ggacgtcggc
     5521 gagatcgttc cagggctggt agccgaggag gtgggtcagg gcggtctgtt cggtgaagac
     5581 ctgttccgcg ccgacgaggt cggcgaggtc cttgcaggtc agcccggtca tggggttggc
     5641 gggctggttg agcatcaggc ggggcaggtc gagcctcacc gcctcctcga tcagcagccg
     5701 cacctcgtgg ccgtcggcgt gtccggtgga gacgaccacg ggcaggtccc gggcggcgcg
     5761 caggagttca cggacgtcgg ggcggagcct gccgctgtcg tcggtgacgg tgagcggacg
     5821 ctggccgtcg gcgagcaggg ggtgggaggg cgtgcgggtc aggcggctgc ggtgcgcccg
     5881 gccggtgacg gtgggcaggt ggacgatcag ccgcaggccg ctgtcctcgc cgtgctggac
     5941 gacggcctgt tccaccgccc gcgggtcgaa gccgccggcc aggtcgttga ggacgaccga
     6001 acccgagacc ggcaggccct gctgccgggc ctcccacgcc tgggcggcgg tggagcccag
     6061 gtggttcttg aggaccaccc agccgccgtg ctcggcgtag gccgcggccg cggtcgtcgc
     6121 ggtgcggcgg cgcacatacg cgtcggggcc gcagtggtag tggacgtcga tgaagcgggc
     6181 ggtccgcgcg ccgccgtcag cggccgtcat ggcggccccc gtcctcgtcc tcccacgggc
     6241 gcgcgtagcc gaagcgggcg cgtgccccgt cgagccggcc gccgtcgagc acggcggcgc
     6301 ggatgcgtgc ctcggtgcgg tcgaccgcct cggcgcggcg caggacttcc gcggccagcg
     6361 cggcgggcac gcgcagcgcg ccgttgtcgt cggcgacgat ccagtccccg gggtcgaccg
     6421 tggtgccccc gatgtccacg ctcaccccgg tccggtccag gacgacccgg ttcttgccgc
     6481 tgaccatggt gacgccggtg ctgaacaggg ggtagccggc ggcgcggctc tccgccacgt
     6541 cgcgcaccga gccgtggacg acggtgcccg agacgccgcg gtgcagggcg acggagctga
     6601 gcagggagcc ccagttggtg caggtgaggc tgccgccgtt gtccacgacg acgacggagc
     6661 cggccggcac ctcgtcgatg tagtcggccg cgttgcgaaa gccccgggcg tcggcgtcca
     6721 gcgggcggta gcggacggtg aaggccggac cgcaggcgag ggtgcccggc gtgcgcgggc
     6781 ggatgcccgg caggacgcac ggcggggtgc gcaggctgtc catggcgtcg gagagggcgg
     6841 cggtgtccag ccgcgcgagt ctccggcgca gctcgccggt gtcgccggaa ggggccgtgg
     6901 cggtggtcat gcggggtcct ccgggtgggg gtggccggtg aggtgccggg tgagggtcca
     6961 ggcggcgtac tgggcggcgt aggccgtgac ttcggcgccc cggttgggga cggtcagggt
     7021 gtccgtccgc tcgtccgtcc cctcgtgcac cgcgcagttc agggcgacgg tgccggtgta
     7081 ggtggtccgg tccccgccct cccaccggcc ggacagggtg acccgcaggg ggcgcgagcc
     7141 gtcgccggtg ccgcgggcgc gggccagttc ggcggcgaag aggcctccgg tgagccggtc
     7201 gtccacgtcc aggacgacgt cgtgctcgtc cagcacggcc gccagttcct ggacggcggt
     7261 gcggtcgcgg tcggtgacga cgtgacgggc cagggtggcg tcgaggcgcc gcgcgaggtc
     7321 cccggcgtcc tcgggcgggc aggtgacgcg gatgtcgacg taggggtagt gccagcggta
     7381 ggccgtcctg gccgggccgc cgtactcctt gaccagggcg tcgaccaggg cggccgcgtc
     7441 cgcctcgatg acgccgaggg tgcggcggaa gagggtggtg gtctcgggcg gacgggggat
     7501 gtggggcagg ccgtcgcgca gcgactcctc cagcatgggc aggcattcgc gcggcgggcc
     7561 ggggagcatg aggacggtgc tgcctcggga ctcgacgcgg cagccccacg cggtgccgcc
     7621 gggattgggc agcagttcgg cgccctcggc gaacagcgcc tggcggcggt tgtcgtcgtg
     7681 cacggcgacg ccgaagcggg tcaggcgggc cacgacggcc tgccaggcct cctcccggtg
     7741 ttccagcggc cggccgagcg cccgggccac ggcgccgcgg gtcacgtcgt cggaggtggg
     7801 gccgagtccg cccatgacca cgacgacgtc gtcccggccc aggcaggagc ggaccgcgtc
     7861 ggcgatgccg gcctcgtcgt cgcccacggt gtgccgggcg cggaccggga tgccgcgttc
     7921 ggccagcatg cgggaggcgt ggcccgcgtt ggagtcctcc aggtcgccgc gcagcagttc
     7981 gtcgccgacg gtgacgacgg ctgcggtggg ggcctgcggg agggcgcggc aggcgtcgac
     8041 gaccgcctcg gccgcctcgg cggtggtggc cgagccgccc aggtcgtagg tgacccggtc
     8101 gcgccggcgg gtgacgtgcc gtacggcgtc cttgaccgcg cccgcctcct cggtgaaccc
     8161 gaggtggtcg agcatcagcc cgatggtgag gaacgcggcc gtggggttgg cgcgctgccg
     8221 gcccgccagg gcgggggcgc tgccgtgcac cggttcgaag tagttgccgc tctcgccgat
     8281 gttggcgctg ggcgccaggc cgagtccgcc catgacgccg ccgccgaggt cggagaggat
     8341 gtcgccgaac atgttctcgg cgacgatcac gccgaaccgc tccgggcgcc gggtcatcca
     8401 cagggcgacc gcgtccacgt tgagcacctc gtacgggatc tccgggtagt cgccggcgac
     8461 gcgttcgagg cggtccagga cgtacgcgct ggagtcgcgc aggacgttgg gcttgtcggc
     8521 gagggtgacc cgctcgtagc cgtgggtccg ggcggtctcg aaggcgaagc gcaggatgcg
     8581 gtccaggccg tgcgcggtct ggaggcggac ggaggcggcc gccccggtgc gggtggagcg
     8641 gcggacgttg gggtggtcgg cgaccagcgg ccacagcgcg tcgggcacgg ggctgaagtc
     8701 cagtcccgcg tacaggccct cggtgttctc gcgcaccacg cagtagcggt acggggtggt
     8761 gccgccgagg tagttctcca ccggtcgcag gttggcgaac aggtccaggc ggcggcggag
     8821 ttggatgatc ggcgagatgt accgcggggc gctcgcgcgc agttcggggg cgagttccgc
     8881 cagtgcctcg ccgcgcggtt tggtggtggt ggcgccgagc agtacggcgt cgctgcggtc
     8941 gatcaggttc caggtgcggt ccgggacggg gttgccctcg gcgcgccagc actcccagcc
     9001 gatgtcgccg aattcgaggt cgagggggag gtcgagggcg tcgatcaccg gcaacgcggc
     9061 gtccagcacc tccggtccga ttccgtcgcc ggggaggacg gcgacggtct tgcggttcat
     9121 gtgagttcag ctcccaggaa gcgggtgagg gtgtgccgga cgaggtccgg ccggtcggcg
     9181 tgcgggcgca ttccggcccg cggtacggcg acgagacggt ggtgcggcag cggtcccgtc
     9241 gccaggtgtt cgcgcccgac gaggcgggac cgttcgccgt acacgtgcag cagcggcccg
     9301 gggaagtccc gtaccgggtg ccgggcgtcg gcgtcgtgca gcaggcgcag tccggcggcc
     9361 agccggcggg ccgccggttc gtcggccgcg gtggggcggg cggaggccgt cggggcgggg
     9421 gcgtccggcg cggtggggcg ccggtgtgcg gcgccggccg gcccgtcggg gccgcgcact
     9481 acgtcctcca gcaggcgggt ggccgccggc aggccctcgg cgtcggccgt cgcggcgatg
     9541 cgttcgagtg tggtgttcag ccggtggtcg gcgaccgtgg gcccggagag cagcagcact
     9601 ttggcccggt gggtccactc ctcgccgagc atgccctgga cgacggcgcc gcccagggcg
     9661 ttgccgacca ggacgtccgg gggcgcgtgc cgcgactgac cgggcgcgcc gggtgccggg
     9721 cccgggtcct tgcccggtgc gaggtaccgg gcccagcggt gcacgaggct ccccaggtcg
     9781 tcgccgtcgc gcagcaggga cagggtgtcg tggatcgtga cccggtggcc cgagtcgagg
     9841 aacgggccgg cgatccgccg gaagaacgca ccgtggtccc accgggcgag gacgggggcg
     9901 aggacgatcg cgtggcgcgg ggagccggcc gggcccagca cggcgtgagc cgggaccggc
     9961 gccgcgtcgt gcgtgggctc ggacggtggg cctggcgggg tcaccgggcg cctgtggcgg
    10021 tgagttcgcg ggccgccgag aaggcgtcgg agatacggcc ctgggggagc ttggcgcgct
    10081 cctcgacgga caggtcgaag tggcccagga ccaggtcggg caggggcagg gagggtgcgg
    10141 cttcggcgaa ctcgccctcc atgcggtggg cgagggcgag gatccggccc aggtcgtggc
    10201 cctcggtgct cccgcgcctg ccgaggtagg ccagccactg ttcggtgacg aggttgcccg
    10261 gccccttgcc catgcccagg acggaggagt cgatccacgt cgcccccgct tccacggcgg
    10321 cgatggcgtt ggccagggcc agtccgagat tgttgtgggc gtgcaggccg atggccgcgt
    10381 cggtcaccga gcggaccagg gtcaccagcc gggagacctc gcgcggcagc atgctgccgt
    10441 tggagtcggc caggtagacg acgtcggcgc ccgagtcgcc cgacatggcc gccagttcgg
    10501 ccaggcggcg gccgtcgagc tggctgacgc gggtgatgtt gacggtggtg gcgaacccga
    10561 ggtccacggc ccgggcgagc agggcgagtc cggcctcggg cgcaccggag ggcaggcaga
    10621 agcgcaccat gcgcgcgccc gcctcgtaca tgcgcggcag gtcgtcctcg gtgatgttct
    10681 tcgggtgcac gatcatgcac aggtgctccg gcgggacgac ctcggcgagg gcgcgtatgt
    10741 agtcgtccgc gcccagtccg gtccggccga tgtccggccg cggcttgaac gagccgttgc
    10801 ggtagccgat ctcgatccac tccatgccgg ccgcgacgct ctcccggacg tggtggcgtg
    10861 cgtagtcgag cgggaagtcg aagttgttgc ggtagccgcc gtcgcgcaac gtcacatcaa
    10921 gattgatgac catttctacc cctccatgaa tggtgcatgc aggcaggcgg ggcgacggtc
    10981 cgcgcggctt tccgcgcgga ccgacaaaga attgggaaac tgttcattct gttgcggggg
    11041 atcccgatgg acccgctccg catcaccccg ttgataaacc gcgaagaact tcggtattca
    11101 accagcttcg tactgaagga agttcttcga cacgggacac gctatcccac gatgcgagca
    11161 ggactttaat gcacaggtaa agaatcaggc ggagggttct ttacccgcgg acttctcacg
    11221 cacgcgggca ctggtttcgg tcagcagtct cagccgttcg ggatccgcgt ccgcccgcag
    11281 ggccagcgac atgcgaatgg cgacgggctc gccgtcgatg ggcagcaccg cgacgcggcg
    11341 cgaggagacg gtgccggccg ccgccgggta catcggaatc cagccggccg cccccgcgcc
    11401 gatctcggcg agggtctcct gaagaccggt cgagggcgga ccgagggcgg gctcgaaacc
    11461 cgccttgcgg caggcgagga ccaccgtgtc gaagagcacg gggttctcgg cccggggggc
    11521 gatgcgcagc ggcaggcggg ccaggtccgc caggcgcagc cggtcgcggc cggccaactc
    11581 gtgcgcggcc ggcagcgcca ccacgagcgg gtcctgccag aggctgagaa gcagcaggcc
    11641 aggggcgctt tcgaggccgc ggacgaaggc cgcgtcgagg cgtccggcac gcacctcttc
    11701 cagccgggtg tgggcgtcca gggtctggaa ctcgaaacgg gtcccggcgc cccggtcggg
    11761 cagcgcgtcc aggaagtcgt cgagccgctg cccgagggcg gagctgatgc cgacgcggaa
    11821 ggtggcgtcg ccctgggcgg ccaggcgtcg ggccgtcgcc gcgaaggagt ccatcgccct
    11881 gagcacctca cggccctcgg gcagcagcgc ccggccggcg ggtgtgaggg tgacggtgcg
    11941 gccggaacgg tcgaagagct cggcgctcag ctcgcgctcc aggcggcgga cctgctgact
    12001 gaccgccggc tggccgatat gcagacgttc ggccgcgcgg ccgaaatgca ggtcttcggc
    12061 gaccgccacg aagtattgaa tctgacgcag ttccacggtg tccccctcgg cggccggcga
    12121 cccctttacg gaatatgccg aacacaggcg ggtgggggcg ccgcgaggga aatcctcgca
    12181 taccgcggag cggcacctcc cccaggaggg ccgctcacgg cggagcgcga cacgacgggt
    12241 tcttcggtga cggttcggtg aggatttcgc cgaggccgcg gcggaaccgg tccggtcctt
    12301 ttactcggcg acggcctcct gaacctcctt gggacgcccg cccgcgtcgg tcgccacggt
    12361 cgcggtggtc gcgacgggcg cggcggtctc ggcggtcgcg gcggccgcga cggtcgcggc
    12421 ggcgtcggac ccgggtttcc cggtcgcgcg tcgccgggac gcgagccaca ggaacagggc
    12481 gaacaggacg acgcccaccg ccgacgcggc cagcacgaac cagcccagcg cgaggaggtc
    12541 accggcgggc agcctgctgg tcaggtagat gccgagcgag gcgccgagca gttgcagcgc
    12601 gcccatcagc ccggacgccg agccggccgt cgtacggaag gccgtcaccc cggcgctcat
    12661 cgacagcggc agcaggaagc cgttgccgaa ggtcatcacc ggcatgaaga ccagcaccag
    12721 caggccccac cgcccgcccg cgccgctcag tcccagcccg agcatcagca gcgcgccggc
    12781 gaggaagaac ccgtggccga cccacagcag ttcgtcgatg cgccgcctgc ggaccaggga
    12841 gcgcgaggtc aggttccccg ccacgtaggc gacggagacg gtgatgtagc agtaactggt
    12901 cgtctcggtc gccaggccca tcttctggaa gaccagcggc gaggcggcca ggtagccgaa
    12961 gtaaccgccg taggcgacgg cgaggttgat ggtgtaggcc cagaaccgcg ggcgggtcag
    13021 caggccggga tagcccttga gcgtggcccc caggtgcttg ctgcgccgct gcggcggcag
    13081 gctctccggg atgcgcgcga ccatcacgac cagcgtcgtc agcccgatca gcgcggtcac
    13141 cgcgaacggc gcccgccagg agacgtacga ggtcagatag ccgccgatca acggcgcgac
    13201 ggacggggag acgcccacga tcggcatgac ggtggcgaag gtcctggcgg cctccttctc
    13261 ctcgtacagg tcgctgatca cggcccgtcc gagcaccatg ccggccccgg cgccgagcgc
    13321 ctggagcagt cgtcccgcac cgaagacctc gatggtgggg gccaccgcgc agaccaggga
    13381 ggcggcgacg aacaggccga gcccgaagac gatgaccggt ttgcgcccgt acgcgtccga
    13441 gatgggaccg tagaccgcct gcgagacggc gatgccgatc atgaacgcgc tgaacgtcca
    13501 ctgcacggac gcgaccgggg cgtcgaaggc ctgcgcggtg tcgggcacgc cgggcaggtt
    13561 gatgtcggag gcgaacagac caccggcgtt cagcgagcac agcacggcca gcagcagcgc
    13621 gtaggacgtc cgcgcgggtc tcggtaccgg tgtcgatgcg gttctcatgg cgactctctg
    13681 cgaatgagga tgccgttccc ggccgggaac gagggggacg gttcccggcg ggaacggcgg
    13741 ctgcgggccg tcaactcctg gcggcgcggg cggcgagggt gtccccgccg atcgaccagc
    13801 tgtcggtggc gatctcctgc accgtcaccc acacgctctc cggcttgctg ccggtggcgc
    13861 tcacgtaggc gtcggtcagg gcgcgcacca gctcgctctt ctgctcgggg gtcctgccgg
    13921 gggtctgctg cacgtggatc aggggcatga cgtgctccgg ggctcgttct ggactgcgga
    13981 cacaacggcg tacgccccgg cgccgtgggc cggggagtcg ctgtgttccc agtccagcac
    14041 cgggcgcggg gccgtccaag acgcagtccg ctctggccac gatcacgaat cgtgatgaga
    14101 cacccccccg ggccggcgga cgcggccccc gtgttccggc cgccggtcag gccggctgca
    14161 actcctcggc ggcgcgccag gcgtggtcgg cgaagcgggc ggcctggggg tgggcgccgt
    14221 gcgagggata ggtgaggtag gcgggcacgg tgggcgcgcc ggtcagcggc atgatgcgca
    14281 cggaggggtg cgtgtagcgg cgggcggcgg agacgggtgc ggtgcccacg cccaggccca
    14341 cggcgacctg ctccagccat tcgtcgaagt tgcggcactc ggagccgacc acgggccggc
    14401 tgccggcggg ccacatgtcg gggaaggtgg tgccgctgac gatgttgacg atcagcggca
    14461 gcccggccag ctccgcccag tcgagttcgc tgcgctcggc cagcttccag cctgccggga
    14521 cggccgcgct gcgcggctcc tcgtagagga ggacaccccg cagccccttc ggcaggggcg
    14581 tgctgcgcag cagggccacg tccgcccggc cggtgtcgag tccggcccgg ggggtgtcgc
    14641 agcggatgaa ctcgaccccg gtgccggtcg cttccgtgaa ccgggcggcg agccgcgaca
    14701 ggccctcggg cagtccccag ctgaacccga cgcgcagtct gtccccgttg cgcaggtcgg
    14761 tcagcgcgga gtcgagttgg cgcaggagcg ggacgacggc ttcccgcaaa gcctctcctt
    14821 tgccggtgag ttccgttctg cgggtggtgc gctcgaaaag ccgcacgccc aaagactcct
    14881 caagtgtcct gatattgcgt gtcagggtcg gctgggcgag atgcaaccgg tgtgcggcgg
    14941 ccgtgaaacc cccctcctcg gcaacggcca ggaagcaacg gaggtggcgc agttcgacat
    15001 tcattcgttg agcgtatagg tggttcggta acgtcatttc tcccacacct tgcgcggcgt
    15061 ctagtcttcg tggtgccgcc gggcggaccg tgcgcccgac ggcaacgggg ttactgtgca
    15121 gcgatattga cgcgcaccgt caatcgactt ggcgcaaaga tcgaccaaag ggcgagcaaa
    15181 ggcgtcggct cccggccgtc ccgcggacgc gatgtccgcc gcccccgatg gttattccct
    15241 caactatttc cgttcggctt cccggcacat tgccggggcc tcggccgcgc caccgggttc
    15301 cggcacggcg ccccgtccgt tcgccctgcc cgaatgcccg ctccgccacc gtaaacactg
    15361 agaaggattg tgctgtgccg gtcatcacca tgcgcaacgg tcccttggaa cacgtcgtca
    15421 tcgacggcga tcccgacctc tcccccctgg tctttctgca cggcggactc ggctgcctcg
    15481 cggcctgggg acgattcccc gcccggctcg ccgccgccac cggacgccgc gccctcgtct
    15541 actcccgcca cggccacggc ggcagcggac ccgacccgct gccccgcacc gtccgctaca
    15601 tgcacgagca cgcccacgag gtgctgccgg aactgctcga cgcgctgggc atgcgccgcc
    15661 ccgtcctggt cggccacagc gacggcgcct ccatggcgct gctgcacgcg tcggcgcacc
    15721 cggtccgggc ggtcgtcggg atgggcccgc acctgtactt cgaggaggag aaccgccggg
    15781 gcatcgagaa cgcccgcgcc tcctacgcgg cgggtccgct cgcccgaaag ctggccatgg
    15841 tgcacgacga cccccgaggg gtgttcgacc gctggagcgg ggtctggctc tcgcccgcct
    15901 tccgcgactg gtccatcgag gacgaactcg acgtcagcgc accggtgctg gcgatccagg
    15961 gcgacgcgga cgagtacggc accctggccc aggtcgacgc ggtcgaacgc gcggtgcacg
    16021 gcccgttcgt gcgcctggtc cccgaaggct gcgaccacta cccccatctg gtccggcccg
    16081 gactcgtcgt cgacgccgtc cgcgcgttcc tcgccgaccc cgccgccccc tcggcgcaca
    16141 ccgggcacac cgcgcacacc gaccggatac cgtccgccgg agccggccgg tgaccgcgac
    16201 gaccgcaccc cgcctcgacg ccctgctggc ccgcgccgcg cgcgaccacc ccgggcgcac
    16261 cgccctggag ggcgccggcg agagctggac gtacgcccgg ctggagcggg ccgtcgacgc
    16321 gctggccgcc cggctgtccg ccaccggcgt cgcccccggc gaccggatcg gcgtccacgc
    16381 gcccaagtcc cccgccaccg tcgtcgccct gtacgcggtg ctgcgggccg gggcggtggc
    16441 cgcaccgctg gacaccgcgg acccgccgga gcggaccgcc cggatgatcc gcaacgcggg
    16501 tctgtcggcg ctgctgaccg tcgaccgcac cctgaccggg gcccgccggg ccgtcgcccg
    16561 cgcccgcgac ggccgccgcc gcgacgacgc gccggccacc gcggaggccc tcgaccacgg
    16621 cctgcacctg ctgcgttgcc tcggccccga cgagcggccc gcgccactgc ccccgccggc
    16681 cgaccggggc ggctacatcc tgttcacctc cggcagcacc ggctggccca agggcgtcct
    16741 gctctcgcac gagaacgtcg cgcactacgc gctgtgggcc gcgcgggagt tcgggctcac
    16801 cccggaggac cggatcggct cgcaggccgc cctcaccttc gacctgacca ccttcgacct
    16861 gttcagcgcc gccgccgcgg gagcctgtac ggtcctgatg ccggacccgc tgcgggtctt
    16921 cccgcgcgac gtcgtcgcgt ggctgaccga acagcgcgtt accgccttca tggccgtgcc
    16981 gtccctctac cacgccatgc tccagcaagg cggtgtcgcg gacgccccgc cggccaccct
    17041 gcggatcgcg gccttcggcg gggagccgtt cgcccccgaa ctgctcgaac ggtacctgag
    17101 gttgttcacc ggggtgccgt tctacaacct gtacgggccc accgagacca acgcctgcac
    17161 ctactaccgg gtgccggccg actggacggc cggccgggaa ctgcccatcg gccggggcat
    17221 cggcggcgtc cacgtcgacg tgctcgacga cgagggccgg cccacggacg gtgagggcga
    17281 gatccacatc gcgggacccg tcgtcttcca gggctacctg cgcggcgggg cgcccgagga
    17341 ccccaccgtc accgccgtct tccgcgacgg cgtcgcccgc cgcgcctatg ccagcggtga
    17401 cctcggccgg atgcggcccg acggacaggt gctgttgcgc ggccggcgcg accaccaggt
    17461 caagcggcgc ggccaccgca tcgatctgat ggacgtggaa aacgccgtcc tggagcttgc
    17521 gcaggtgggc accgccgccg tcgtcgcccg ggagggcgcc cgcggcccgg acggctcccg
    17581 caccgtcgag atctgggcct acgcgcagac ggacgccacc gagcacgagg tcctggccgc
    17641 gctgcgcgcc gtactgccca agcggatgct gcccgaccgc gtcgtaccgc tcaccaccct
    17701 gcccaccacc accagcggaa aggtcgaccg ccgcgccctg agcggcacgg ccggccccgc
    17761 gcacccggag gacgtcaacg tatgaacagc gtcgaagaac tctgcgccct gatcggcagc
    17821 cgcatcacct ggggccccgg cgaggacgcg agctccctga ccgccgacac cccgctcctc
    17881 gaaatgggcc tggtcgactc gctggcgatc atggagatcg tcgcggcgct cgacaaggag
    17941 gccggcgtca ccctgcccga caccgagatc gtcgccgcca acttccgcag ccccaaggcg
    18001 ttgtgggccg cgatcgaggg cctcgccgtc gagggccgcc catgagcgcg acgcccaccg
    18061 cggcactgcg ctcgtgcgca ccggagaccg aagagatcgt cgacgcctac cgggacctgg
    18121 ccgcgccggt gacggagcgg gccggggacg cggacttcac cgcccggtgg cgggcgatgg
    18181 ccgacctcgg tgtgctccgc ctcgccccgc ccgacgccac ggcgcccggg ccggtcaccc
    18241 gcgccctcgc gatgatcgag ggcatcgggc tggcgggcgt cgaccccggc ctgtgctacg
    18301 cgctggcctc ccaggtcttc gggatgcagt tcccgctgcg ggccgcgctc ccggcggcgg
    18361 cccgggacgc ggtcgccgac gtccaggacg gccggaccct gctctgccac gcgctgaccg
    18421 aacgcggggg cggcagtgac ccgttctcca tggagacccg ggccgtgcgc gacgccgacg
    18481 gcttcgtgct cgacggcgcg aagacgttca tcaccgcggc gccggtggcc gaccgggcga
    18541 tcgtcttcgc ccgcaccgcc ccggggcgct caccgttcgc gctgtccgcg ttcctcctcc
    18601 ccctcgacct cccgggggtc cggcgcggcg agaccttcgc caagaccgcg ctgccgaccg
    18661 tgccgatggg ggagctgatc ttcgagggcg cccggctgcc cgcggacgcg ctgctcggcg
    18721 aggagggctc cgggctggcg gtgatggcct cgaccaccgc ctgggagcgc tccgtcatcc
    18781 tcgggtacgc cctcggtccg atgcaccgtc tgctgacgcg caccgtcgag tgggccgccg
    18841 gacgggacca cttcggccgg cgcatgggcg ccagtcacca ggtcgccgct cgcgtcagtg
    18901 acatggccct ggcgctgcac cgctcccgcg tccagctcta cgcgatggcc gcccggctcg
    18961 acgccggcac acccgcccgg cagctggccg cccaggccgc cctcaccaag atctccgtgt
    19021 ccgaggacta cgtgcggatg accgagcacg ccaccgcgtt gtccggagtc cgggccttcc
    19081 tgcccggctt cgacctcgcc gcggacctgt cgagccccat ggcggccctc acctacgccg
    19141 gtccgaacga cctgctgcgg gtggccgtgg cacggcaact cggcctgccc gtcgagaact
    19201 gacgggacga cggccgacgg cccctcaccc gtcaaccggc cgatcgacac cccgacaacg
    19261 gccggtctcc gaccggccgg gcaccgaccg atcgagaccc ggccggccga cgacccaccc
    19321 accggcccgg caccgacccc caaggacacc tatgacgctg ccgacccact tcgacgacct
    19381 cctcaaactc gccgccgaca ccggctccgc gatcgccccg ctcgccgccg ccaccgacgc
    19441 cgcggacgac gacggccacg aggcctaccg cgtcctgcgc gagtccgggc tgctcgccct
    19501 gctcgtgccc cgggaggccg gcggcgccgg tctcggcttc ggcgactact ggcgggtgct
    19561 ggccgaactc ggtgcgcacc acggcgccgc ggccctcggc ttcaacatgc accacgtcgt
    19621 gatcggcgcg ctcgccgaag ccgccgggac ccggctgtcc ccggccgccg acgccttccg
    19681 gacctggatg ctgggcgagg tggtggacgg gcgcaagatg ttcgcctccg ccacctccga
    19741 ggcgggccgc ggcgcgaagc tgcgcggcat gcggacccgc taccgccgct ccggcgacgg
    19801 cacgcactac gtcctgaacg gcaggaagga cttcgtgtcc ctggccggcg ccgccgacta
    19861 ctacgtcgtg gccgccgccg acggggacga cgaggagagc gccgagatct cgcacttcgt
    19921 cgtcgccgcc gacgacccgg gcgtcggctt cggcccggtg cggcacctgt cggcgatgta
    19981 cggcaccagc accgcgccga tgacgctgga cgaggtggtg gtgccccgct cccgcctcta
    20041 cctcggcgtc gagggcatgt ccctgttcaa ggtggtgcgc gagccgcact ggatgttcgc
    20101 cggctacacc ggcgcctacc tgggcatggc tcaggccctc taccggcaca ccgtggaccg
    20161 tgtcaccgcg gcccccggcc gcgccgactc ccccgtcgtg cagcaggaac tgggccggat
    20221 gtccgcccgt ctgcgggccg cccgcgccct ggtccacgag gccggcgacc tggtcaccgc
    20281 ggaacgcggc agcctggagg ccaacgccat ggtgcacgcc gccaagtacg tcgtgggcga
    20341 gaccggaccg ctactcgccc aggacgcgct gcggctgtgc ggctcggccg ccgtcagccg
    20401 cggtcacacg ctggaacggc tgatccgcga ggtccagttc gcgcacgtga tgccggccaa
    20461 gccgcacgag tgcctggagt acctcggcaa ggccgcgacc ggcgtcaacc tctacgacgc
    20521 ccggaccttc tcgtggtgac ccccgcgagc acgaccgcct cgatgccccc cgcgccccgt
    20581 gccggggacg aacgcgccgt gccgcacgac gccttccggg ccctgatggg ttcgcacccc
    20641 agcggtgtcg ccgtcgtcac cacggccgac gcgcggggca caccgtacgg cttcacctgc
    20701 accgcgctgt gctccgtctc cctcgatccg ccgcaattgc tggtgtgcgc ggcagccggc
    20761 ggaagcaccc tgcccgtcct cgcggcccgc ggggccttca ccgtgaacct gctgcacggc
    20821 agcgggcggc gcgccgccca ggcgttcgcc ggtccggccg ccgagcggtt caccaccgtg
    20881 ccctggcggc ccgggcacct caccgggctg ccggtactgc cgcaggactc ccacgccacc
    20941 gccgagtgcc gcgtcgcccg gacggtcccg gccggcgacc acaccatcgt gatcggcgag
    21001 gtcctgcaca ccgagaccca tgtcccggcc gccgaggccg cgcccctgct gtacggcatg
    21061 cgccgctacg cgtcctggcc ggtccgaccc ggccgcaccg tcccgtccgt gtcccccgcc
    21121 ccgtgaagga gccctcatgt accgcaccct gatgaagtcg aagatccacc gcgccaccgt
    21181 cacccaggcc gacctgcact acgtcggatc ggtcaccgtc gactccgacc tcatgcacgc
    21241 cgccggcctg ctccccggtg agaaggtcga catcgtcgac atcgacaacg gcgcccggct
    21301 gtccacgtat gtcatcgagg gcccggccgg caccggcgtc ctcggcatca acggagccgc
    21361 ggcccggctc atcagccccg gcgacctcgt catcctcatc gcctacgccg ccatgaccga
    21421 cgaggaggcc gcctccttcg tccccgacgt cgtgttcgtc gacgagcaca acgccgtcgc
    21481 gggcctgggc tcggacccgg ccgaggtgcc cgcgggctcg ggcctcaagc gcggcgacct
    21541 cgtcgccgag gtgtcatgag cctcgccgtg gtcagcggcg gcacccgcgg catcggacgg
    21601 gccctgagcc tccggctcgc cgccctcggc caccgggtgg tcgccctcta ccgcggtgac
    21661 gacgacgccg cgcggcagac cgagaaggcc ggtgacggcc ggatcgaggc gctgcgctgc
    21721 gacctggtcc ggccggagga ggtccgggcg gtctgcgcgt cgctcaccgc ccgccacggg
    21781 gcaccctccg tgctcgtcaa caacgccggt gtcaaccgcg accggccgtt cctgtcgatg
    21841 accgaccggg actgggacac ggtcctggcc accaacctct ccggcccctt ccacctgacc
    21901 cgcgccctgg cccccgcgat ggtggaggcc ggtgggggca gcatcgtcaa cgtcgcctcc
    21961 accacggcga tccggccccg cgccgacggc gccaactact gcgcgagcaa ggcgggcctg
    22021 ctccagctca ccaagtgcct ggccctcgaa ctcgccccgc acgtccgggt caacgccctg
    22081 ctgcccgggt tcaccgacac cgaggaggtg accgagcgct accgcctgga cgacccggaa
    22141 cggctcggcg ccgtcctgga caccattccg cgcggcaggc tcggcacggc cgaggacatg
    22201 gccgacgccc tggagttcct ggtgggcgcg cgcagcggct acgtcagcgg gcagcaactc
    22261 gtcgttgacg gcggccactt catgggatga cctccgcatc gtcccgtccc ccgaccgatc
    22321 aggagaacaa gcgcatgcga ctgacccagc aacaggccgc cgagtaccac gagcgcggct
    22381 tcctcatgct cgaatccctc ctcgacgccc aggaggtgga gacactgcgc gccgccttcg
    22441 aacgcgacgc gaaggtcccc gggccccagg tggtgaccga ggacggcggt acggaggtcc
    22501 gcgccgtcta ctcctcgcac cagcggcagc aggagtacgc cggactggtc cgcgacccgc
    22561 ggatcctggc accggtgcgg caactgctct gcgacgacgt ctacgtctac cagttcaaga
    22621 tcaatgccaa accgccgttc ggcggcgaca agtgggcctg gcaccaggac ttcctggcgt
    22681 ggcgcatcgc cgacggcctg cccgccccgc gccaggtcaa catcggcgtc ttcctggacg
    22741 acgtcaccga gttcaacggc ccggtcatct tcctgccggg ctcgcaccgg cgcggactgg
    22801 tccgcgaggg ccggtcggcg tccgccaggt ccgagcagca cctcgacccg gacgacatat
    22861 ctctgtcgcc ggggcagctc gcggagtacg tggaccgcca cggcatgacc agccccaagg
    22921 ggccggccgg ctccgtcgtg ctgttctccc cggagatcgt gcacggctcg tcccccaaca
    22981 tgtcgccgtt cgcgcgccgg ctgctgatcg ccacctacaa cgacgccggg aaccttccgc
    23041 ggccacaggg cgaaccccgt ccggactacg tggtgtgccg ggacaccgcg ccgctgcgcc
    23101 cgctggcggc cccgttctcc caggtgccgt gcgcggtggc gtcgtgaccg cccgcgccgc
    23161 tacggcagcc gccaccggac gcgccgtcgt cctggaggag ttcggcaagc cgctggcgct
    23221 gcggacgttc ccgctgcccg ggccgcccgc cggcggcatg gtcgtggcct gcggctacgg
    23281 cggtgtctgc gggaccgatc tgcacctgtg ccagggccac ctggacatcc cggtccccct
    23341 cgtcctgggc cacgaggggc tgggcgtcgt acgggagctg ggtgccggca ccgaccggga
    23401 cgccgccggg acaccgctgg cggccggtga cacggtgatg tgggcgtcct ccatctcctg
    23461 cggggtctgc ccgccctgcc ggctgcaccg tgagccgacc ctgtgcgagc ggcgccgcac
    23521 ctacggcgtc aaccgggccc tggccgacgg gccggagctg tccggggcgt gggccgacca
    23581 catcgtgctc cagccgggca ccgccgtgat caaggtgccc gacggcacgg acccgctcgc
    23641 cgccatgtcg ctggcctgcg ccgggcccac cgtggcgcac gcgctgttcg agaggcggcc
    23701 ggtgcggctc ggcgagaccg tggtggtgca gggcagcggt ccggtggggc tggcggccgc
    23761 cgccttcgcg cggctggccg gggccgcgaa ggtggtgatc gtcggcggcc cggccggccg
    23821 gctggagcgg gccgccgacg ccggtatagg tgacgtccac ctggacatcg ccggtgccgg
    23881 cgatcccgcg gaggtgctgc ggcaggcgcg ggccgcggtc ggcggggacg gcgccgacct
    23941 cgtgatcgag tgcgccggtg tgccggccgc cgtcggccag ggcctgggac tggcgcgccg
    24001 gggcggcagt tacctcgtca tcggccagta caccgacgcc ggggacacca cgctcaaccc
    24061 gcaccagatc gtccaccggc aactcgacgt ggtcggttcc tgggccttca ccggtgccca
    24121 tctcgtcgag tacgtgcggc tgctgcccgc cctcaccggc cggttcggcc tggcgggcct
    24181 ggtgacgccg ttcccgctgg aacggcatgc cgacgcgctc gacgcggtcg ccgacgggtc
    24241 ggtgatcaag gccgtcctca cctcctgaca ccgcccgtcc cggtgcaccc gacggcccgg
    24301 caggcgcccc gcgcgcggcc gggccgtcac cgctgcccgg cgagcagctc cagcccctgt
    24361 gccgtcgccc ggtcgtcggg caggtaggcc agcaggtggt ggccgggctc gtccacggcg
    24421 gcgagtttga cgtaccgcag gtggagatca ccggccaccg ggtgccggaa gtggcggacc
    24481 gcggggtgga acgccgccgt ctcccggcgg ccgtaccagc gggcggcgtc gggatcgtgc
    24541 agcagctccc cggtgatctc ggcgtaccgg ccgtcctgcg ggtgccgggc cgccttcgcc
    24601 cggaactggc cgagcagact ccgcgcctcg gactcccaac tggccagcag cgtacgggcg
    24661 ggcggccagc ggaacaccag ccacagcagg ttgcgctgct tgggcgccag ccgcgccaga
    24721 tcggtcagca gtcccgagta gcccgagttc caggccagca ggtcccagtg cgggtcgagc
    24781 accgcggccg gatgcggtgc cagcgactcc accagcgaca gcaggttcgg cgagacccat
    24841 ccaggcggcg gtccgtccgg cgcggcccgt tcgacgaagg acagcacgtg cgcggtttcg
    24901 tcggcgttca gccgcagggc ccgtgccaac gaccgcagca cctgctccga cgtacggacc
    24961 cggccctgct ccagccaggc gtaccaggac gcgctgacgc cggccagctc ggcgacctcc
    25021 tcgcgccgca ggccgggggt gcgccgtcgc ggtgagccgg gcagccccac gtcggccggc
    25081 ccgagccgct cccggcggga gcgcaggaag gctcccagct cgcgccgcgg gtcgccggct
    25141 cccccgccgt tcacgtcctc ggtcctcctc ggttctcccc gcgccaccgg cccggaccgg
    25201 cgcgacgcac cgcgccccag gctgtgagca agggtaatcg gctgcggggc cgggcgggcc
    25261 ggccgcggtg atgagctgga caggccggtc ggaccgtccg gcgaccaccg atcgaggagc
    25321 acttccatgg acccggccga ctcgtcaccg accacctccg caccgcctcc ggccggtccc
    25381 ggcgacccgg ccgacccggc ctccgcgcgc ctggcgaccc ccatgcccgc ggccaccctg
    25441 cgactgctgc gcacggccgg attcgtcagc aacttcgacc ggttctgcat cacccccatg
    25501 ctgctggtca tcggcacccg gctcggcgtc ccgctgacca cggtcatgct cgccgccagc
    25561 ggctacttcc tcgcctacgg cctgatgcag ccggtctggg gactggcgag cgaccggctg
    25621 ggccgggtgc gggtcatgcg gatctccctg gccggggccg ccgtcgccga gctcgcctcg
    25681 gtgctcgcgc ccggcgcgac ggtactgatc gtggcgcgcg tcgtggccgg ggcgtgcttc
    25741 gccgcgtcca tcgccgcgtc catcacctac gtcggtgaca cggtgcccgc cgcggtacgc
    25801 cagcggccgc tcagcgagct gatgaccgcc ttcgcgctgg gcaccgccgt ggccaccgtc
    25861 gtcgccgggg tactggccca ctacgccagc tggcgcgtgg tgttcgccct gccgggcctg
    25921 atcgccgcct acctggtcgt cgccctgcgc cggctgccgg aaccgccgcg cgcggaaccc
    25981 ggcgcgctgc tcgccccctt cgccgtcgtc ctgcgctccc gctggcagtg gtacgtcatg
    26041 gccgtcgcgc tgttcgaggg cgccgtgctg ctgggcttcc tcacgtacat cgcgccggcg
    26101 ctggaggccc agggtgcctc ggccgccctg gccggtgcgg tgaccgcgct gtacggcgtg
    26161 ggctcgatgg ccgcggcgca gctggtcaag cggctggtcg ggcggtggac gccggtccgg
    26221 ctgatcgtgg ccggcggggt gcagatgacg gtggcgttcg gctgtgccgc ggccgaccgg
    26281 tcggtgcccg cgctggtggt gtgcgccctg ctgctcggcg gcggctggtc gttcatgcac
    26341 tccacgatcc agtcctgggc caccgcgctg tccccggcgg cccgtgcgac cggggtcgcg
    26401 atgttcgggg tggccctcta cgtcggcagc gccctggcca gcaccgtcgc cgccggtccc
    26461 gcggaacgcc acgcctacca cggtctgttc ctcaccgcgg cggtgctcac cgtcccgctg
    26521 acggtggccg ccgcagtggg ccgcgcccgc taccggggct gaccggcacg ggccgccgcc
    26581 gggagcgccc gcaccggacc gccccggggc cgccccgggc gccgaggcgc ggccccgggg
    26641 cgccggtcgg gcatgtgcca agatggcgct gaacaggcgt tcgggggcga cgggttcgac
    26701 ggggggcgaa cggcatggat cggggcgggc ggaccggaca ccgcgcggtg ccgggggcgg
    26761 cggtggccgt cggagtcgtc ggcgccctgg cgctcgccgc gctcgcgctg cggcccgcgg
    26821 aagggctgct gcactccggc cgggggccgc tcggccagtg gggcatcgtg gcgatcgggg
    26881 cgtccgccgc ctggacgatc ggggcttgga cggccgtccg gcgtcttcgc ccgcgtttcg
    26941 gcgccaaccg catggacctg ccgccggtcg aggagcggct gcgggagatc gccgcgcccc
    27001 tgctgctctc cgcgacggcc gtcatcggcg tactggccct ggtcctgcac cggttctcca
    27061 ccggcgacgg cacgcccggt ccgccgccgc ccctcgccac cgaaccggcc cccgaaccga
    27121 cgttcgccac tcccccgccc caggagcgcc cgcgcggttc gggggaccat tccgccctgc
    27181 cgctgcatct cgtgctcctg gcgctggccg cggtcgtcgc cgtgctcgtc gtggtggccg
    27241 tcgtacggcg gctgcgccgg ttccggctga gcctgcccta ccgtccgggt ccgtcgggga
    27301 gcaccgcacc gcaggacgac gacgcgcgac tgctgctgtc cgccgtgcac tcgggccgcc
    27361 gcgccctggc cggcaccgac gacgacgccc gggccgccgt catcgcctgt tacgccgcga
    27421 tggaggacgc cctcgccgcg tccggtgtgc ggcggcaggc ctccgacagt ccggccgacc
    27481 tgctcacccg cgccgccgcc gcgggcttcg ccccgggccc ggccgggccg cgtctcaccg
    27541 ccctcttccg cgaggcccgt tactcctcgc acccgatgga cggctcgcac cgggcggccg
    27601 cggccgccgc cctggaggag atcgcgtccc tgctcgggga cccggaaccc gccccggcca
    27661 cggacgggaa ggtcgagcgg tgaaccggtc cctggaggac ggcccggggc aggacatgct
    27721 gtcactgccc cggctcgggc tgctgggcgg cgcggtcgcc ggctcgggcc tgctgctcgt
    27781 cctgc
//
