LOCUS       NZ_CP085300            28233 bp    DNA     linear   CON 18-JAN-2024
DEFINITION  Streptomyces sp. BSE6.1 chromosome, complete genome.
ACCESSION   NZ_CP085300
VERSION     NZ_CP085300.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. BSE6.1
  ORGANISM  Streptomyces sp. BSE6.1
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8024389)
  AUTHORS   Ramesh,C., Anwesh,M., Vinithkumar,N.V., Kirubagaran,R. and
            Dufosse,L.
  TITLE     Complete Genome Analysis of Undecylprodigiosin Pigment
            Biosynthesizing Marine Streptomyces Species Displaying Potential
            Bioactive Applications
  JOURNAL   Microorganisms 9 (11), 2249 (2021)
   PUBMED   34835376
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8024389)
  AUTHORS   Chatragadda,R. and Maile,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2021) Andaman and Nicobar Centre for Ocean Science
            and Technology, National Institute of Ocean Technology, Dollygunj,
            Port Blair, Andaman and Nicobar Islands 744103, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 10-OCT-2021
            Assembly Method                   :: Unicycler v. 0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/18/2024 07:10:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,273
            CDSs (total)                      :: 7,198
            Genes (coding)                    :: 7,094
            CDSs (with protein)               :: 7,094
            Genes (RNA)                       :: 75
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 47 of 104
            Pseudo Genes (incomplete)         :: 80 of 104
            Pseudo Genes (internal stop)      :: 9 of 104
            Pseudo Genes (multiple problems)  :: 30 of 104
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 01:03:07
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 804494
            Orig. end                         :: 832727
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP085300.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from National Institute of Ocean
            Technology.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28233
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..28233
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28233
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:18233]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18233
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            689..1420
                     /locus_tag="LJA35_RS03755"
     CDS             689..1420
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978691.1"
                     /locus_tag="LJA35_RS03755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_061441025.1"
                     /transl_table=11
                     /translation="MNTPSAVLTRADGTPVRVLVVDDEPDLAEVVTGALRYEGWDVRAA
                     ASADAAVREARAFRPDAVVLDIMLPDRDGLSVLRDLRAEQPHVCVLFLTARDAVEDRIT
                     GITAGGDDYVTKPFSLGELVARLRGLLRRAGMTRERATDSLLVVGDLELDEDAHEVTRG
                     GDLIDLSPTEFQLLRCLMRHARQVLSKTQLLDLVWSYDFGGGAHVVELYISYLRKKIDS
                     GRAPMIHTVRGAGYVLKPAPQ"
     gene            1417..2883
                     /locus_tag="LJA35_RS03760"
     CDS             1417..2883
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978690.1"
                     /locus_tag="LJA35_RS03760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_212731975.1"
                     /transl_table=11
                     /translation="MRWPRLHTLRARLTAGLLVLLAVACAAVGGAAVLELNGFLTDRLD
                     QQLADTGSAFAASLEHPDTDHDDHDGDERGDTRRQAAETLGVRIADGRVTNAAVVRQGD
                     ASADVVTLEVDAEDARALAAVPTDGQGHSVELTGLGDYRVRAWQGRDGDTLITGLPLEP
                     VEAAVHRLELVAGGVFGLALVGAGVAGALWVRWSLRSLSRIADTATRVSELPLASGTVA
                     LPARAPDTRPRSEEVDQVTTAFNRMLGHVEHALTQRQRSEERLRSFSADASHELRTPVA
                     SVRGHAELALLHPGPLPPEVGRALERIAAESARMGAMVDDLLLLARLDAGRPLEDEPVD
                     LTRLVLDVVDDARAAGPDHRWSLELPQEPIIVSGDRHRLHQLLANLTANARLHTPPGTA
                     VTVGVRRDDDGTACLTVTDDGPGVPPALRDHLFDRFVHGDGPRGADGGGTGLGLSIVAA
                     VAAAHGGTASVTGEPGTTTFTVRLPRRPPG"
     gene            3108..3518
                     /locus_tag="LJA35_RS03765"
     CDS             3108..3518
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.4"
                     /locus_tag="LJA35_RS03765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_233648202.1"
                     /sec_met_domain="PF07366 (E-value: 4.3e-14, bitscore: 51.1,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAGHLDHFTELLHEDVVFDVVPVGLRRGRQAVRRYFEEVRLAMP
                     DLVMTMEHAVGDDRYAAVEWRMTGTFDGAPYQGLAPTKRHTPCRVSTSSKWAPDASGVP
                     EPSSTAPNWAARSASCPPAVQPPTVPRPGRST"
     gene            complement(3620..4222)
                     /locus_tag="LJA35_RS03770"
     CDS             complement(3620..4222)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978688.1"
                     /locus_tag="LJA35_RS03770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4383 domain-containing protein"
                     /protein_id="WP_102932086.1"
                     /transl_table=11
                     /translation="MRLKDEMPVDHHLATVYRYGAGFCGLVLLVFACLGFADALSPFDT
                     AGDTIAGMTTDVALSVISAVVGLTLLAGAAVGGNFASVLNMTVGALFVLSGFFHVFVLD
                     RRANVLDFGMTNVIFSFVMGLVIATFGMYGRASSELSHDNPYWQRRHPEQAAREREAAA
                     ALPDAERRGHTLPAGQGPEHTEAPRSPARRPPGAGMR"
     misc_feature    4251..4266
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.13"
                     /tool="antismash"
     gene            4388..5326
                     /locus_tag="LJA35_RS03775"
     CDS             4388..5326
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016324999.1"
                     /locus_tag="LJA35_RS03775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_233644988.1"
                     /transl_table=11
                     /translation="MHEVATDQAFDARGRRHRDGVGDRPAREPVIRHVPLTWRGLGLDT
                     MASLLVESFARLGSRCFAARCQWPRLHPLNERALGAVTHHPLIMAESARQLALALEYGR
                     PPGTVRARLEPVSVRLGLRLRSWPVERGGATDVDVRMSVSDLVTVAGRPVSHRVTAEFL
                     HTGKSFGSCTMRFARPAGSAVPVEGAPLPGLLHPPAAAVGATADGDVMLARGPRGRLVT
                     APRDPGHPVLLAGRPARMPLLAVLEAGRQAVLLESGMTAAAVIGLRADVCAPVPSRGAL
                     IETSAEPGGSRFLVTASGRPAATGAVTLWSK"
     misc_feature    complement(4404..4419)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.03"
                     /tool="antismash"
     gene            5374..6945
                     /locus_tag="LJA35_RS03780"
     CDS             5374..6945
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978686.1"
                     /locus_tag="LJA35_RS03780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_210914327.1"
                     /transl_table=11
                     /translation="MAANGRQDQERLLCLVTGASGYVGGRLVPELLGAGHRVRCLARTP
                     AKLRDQPWASDVESVRGDVTDPRSVAEAMRGVDVAYYLVHALGAGAGFEDTDRRAARVF
                     AQQAYEAGVRRIVYLGGLTPRGVPERTLSPHLRSRAEVGRIFLDAPVPATVLRAAVVIG
                     SGSASFEMLRYLTERLPVMVTPSWVHTRTQPIAIRDVLHYLVGSATMPDNVDRAFDVGG
                     PDVLTYREMMRRYATVSGLRRRIIVPVPVLTPGLSSHWVGLVTPVPAALARPLTESLRH
                     EVVCQEHDIARYVPDAPGRPLPFDEALALALRRVREAQVATRWSSASVPGAPSDPLPTD
                     PDWAGGSLYQDERELRVDASPEALWKVVEGIGGDNGWYSFPLAWAVRGWLDRFVGGVGL
                     RRGRRDAQHLRVGDSLDFWRVEEIEPGRLLRLRAEMRLPGLAWLEMHVETDAEGRTRYR
                     QRALFHPRGLLGHAYWWSVFPFHAVVFGGMARNIGQAAVKGMTTRRSDDRSWRIRRRRA
                     PRSVEH"
     gene            6983..8356
                     /locus_tag="LJA35_RS03785"
     CDS             6983..8356
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524489.1"
                     /locus_tag="LJA35_RS03785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_233644989.1"
                     /transl_table=11
                     /translation="MTVAVVLFTSDLRLHDHPPLHAALEAADEVVPLFVLDAGIHAAGF
                     DAPNRRAFLADCLSDLDSSLRHRGGRLVVRNGPVVREVRAVAAQCGAAEVHVAAGVTAY
                     AQRREEGLREELGEDGVALRVHETVITAVAPGAVTPSGSDHFAVFTPYFRRWSQVSSRK
                     PLAAPRTVRVPDGVRGEPLPDRADVAGASPGLPAGGETAGRDRFARWSRSGLSRYEERH
                     DDLADDATSRLSPYLHFGALSPLELVHRARAHGGPGAEAFVRQVCWRDFHHQVLAARPE
                     ASVKDYRTRHDRWRDEEDAAEDIAAWRGGRTGYPVVDAAMRQLRHQGWMHNRARLLVAS
                     FLTKTLYVDWRIGARHFLDLLVDGDVVNNQLNWQWVAGTGTDTRPHRVLNPLVQAKRFD
                     PDGIYVRRWVPELRSVTGRKVHEPWRLAAAERGELDYPDPLVDLADGLARFKHARGRD"
     misc_feature    complement(7023..7036)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.32"
                     /tool="antismash"
     gene            8368..9864
                     /locus_tag="LJA35_RS03790"
     CDS             8368..9864
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018843427.1"
                     /locus_tag="LJA35_RS03790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cryptochrome/photolyase family protein"
                     /protein_id="WP_212731970.1"
                     /transl_table=11
                     /translation="MHWLFGDQLGPHFLTPGEGGPGPETPLLMIEARSVFRRRRFHRAK
                     AHLVLSAMRHRAAELGDRVTYVRADTYRQGLERAARGRPVGVHHPTSHAALRLVRTLPG
                     VTVGPARGFLVPMADFAAWADGHGGRRLRQEDFYRWVRRGHDLLMDGEQPAAGRWNLDH
                     DNREPPPREATSLQVGRPYRPREDDIDEEVRHDLDRWEREGDVSFVGRDGPRLFPATRA
                     EARRALRRFVERRLATFGPYEDAMLAADPAMSHSLLSSSLNLGLLDPAECVERAERAWR
                     AGLAPLNSVEGFVRQIAGWREYVWQVYWYFGEDYRRSNALGHTAPLPDWWSVLDADAVR
                     ANCLRTVLAQVRDTGWTHHIPRLMVLGSHALQRGWEPAAVTDWFHRCFVDGYDWVMLPN
                     VVGMSQYADGGRMTTKPYTSGGAYVNRMSDLCGPCVYRPGDRTGERACPYTAGYWAFLD
                     RHRELLAGNQRVARPVRQLDRLGDLPEVLEQEHARGDTPP"
     gene            10001..11143
                     /locus_tag="LJA35_RS03795"
     CDS             10001..11143
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837939.1"
                     /locus_tag="LJA35_RS03795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_212731969.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.7e-45, bitscore:
                     152.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGLPPMVAPPAERVDDPLTASGAAKAVGTVLEEVLDERLRHSRS
                     VDPVFARELADRLAALTARGGKRLRTAFAHCGWRAAGGSGDATAVLRTGAALELLQACA
                     LVHDDVMDGSVQRRGAPALHVDLARRHWAAGMHGSSESFGTSAAVLTGDLALAWADDLL
                     AETALGTPHGTRLHGEWRAMRTEMVAGQYRDLHAQAARSSGVDEALTIATLKSALYTVA
                     RPLALGAVLAGADGDALDALRAAGRCAGLAFQLRDDLLGAFGDPTLTGKPADDDLRSRK
                     LTYLLAVAVRLADAADDHLSAAALAPDADPKSDRAVRQVRSALVRTGARDLVEAKIGEL
                     TDMSLAHFDRCGARPAVRHEFAALVGRATGAVPRGDGEVA"
     gene            11140..12711
                     /locus_tag="LJA35_RS03800"
     CDS             11140..12711
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026910.1"
                     /locus_tag="LJA35_RS03800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene desaturase"
                     /protein_id="WP_212731968.1"
                     /sec_met_domain="DAO (E-value: 1.1e-17, bitscore: 63.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRVPGPTDHVVVVGAGLSGLACALHLLGAGRRVTVVERDAGPGG
                     RAGRVRRAGYAMDTGPTVLTMPHLADEAFAAVGDSLHRRVELTALDPAYRACFADGSSL
                     DVHTDGEAMEAEVRRFAGPAQAAGYRDLRQWLERLYRVQMRRFIDTNFDSPLQLLHPDL
                     ARLAALGGFGRLDGRIGRFLSDERLRRVFSFQALYAGVAPARALAAYAVIAYMDTVAGV
                     WFPKGGMHALPRAMADAAADAGADLRWRAEVDTLERSAGRVRSVRLASGERIACDAVVL
                     TCELPAAYGLLGRAPRRPVRLRHSPSAVILHAGTDRTWPHLAHHTISFGAAWERTFEEL
                     TRTGELMSDPSLLITRPTTHDPALAPPGRHLHYVLAPCPNTHVGPEAAAWRDLGPRYRD
                     SLVGVLEKRGLEGFADSVQEELLVTPLDWDAQGHAAGSPFSVSHTFAQTGPFRPRNLVR
                     GLDNVVLAGCGTNPGVGVPTVLVSGKLAAARVTGGARSRPARTRRSPAVPATYPAPAPA
                     GTDEPS"
     gene            12698..13693
                     /locus_tag="LJA35_RS03805"
     CDS             12698..13693
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026911.1"
                     /locus_tag="LJA35_RS03805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_165288117.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.6e-125,
                     bitscore: 415.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 6.9e-65,
                     bitscore: 217.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRRELDAAGITDPLLRAAYTRCRRLNARHGKTYFLATRLLPLER
                     RSAVHALYGFARWADDIVDDLDRHRTPEERDRLLRRLESDLADGLLTRAGREPVVRAVA
                     DTAGRYGIDHALFADFLSSMRADLTVTHYPTFADLQGYVHGSAAVIGLQMLPVLGTVTA
                     REEAAPHAAALGVAFQLTNFLRDVGEDLDRGRVYLPGDLLAAHGVDRPLLEWSRRTGRR
                     DRRIRAALMAAEAMTRRVYRTAEPGITMLDPRVRPCIRAAFTLYGGILDAIAEQDYSVL
                     HRRAVVSRRRRAATAAAGVLRVAGARLRARTEDRVARAGASAVERKGPVR"
     gene            13690..14700
                     /locus_tag="LJA35_RS03810"
     CDS             13690..14700
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026912.1"
                     /locus_tag="LJA35_RS03810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_142201471.1"
                     /transl_table=11
                     /translation="MSGRGNGKRWSPPLRRRASGPHWAAQTPTWRQARPALIADALKRA
                     SARPSGNWFVVGASRNVRAGDRPYGRTVGGVEVVLWRSEDGEPHAGEGSCPHLGAPLRD
                     SRVVCGTLVCHWHGLALDGSASAGWRPFPVHDDGVLVWVRLDEVGGEEPGERPVVPARP
                     VTGRGVDAVFTAVGRCEPQDVVANRLDPWHGSWFHPYSFVDLSVVREPQGDEDDAFVVD
                     VSFRVAGRLVVPVRAEFTAPEPRTVVMRITDGEGATSVVETHATPLTGPDHERPRTAVV
                     EAVVAASDRPGFAVARAAAPVLRPLMRRTAGRLWRDDLAYAERRWTLRSTGRFPG"
     gene            complement(14714..16282)
                     /locus_tag="LJA35_RS03815"
     CDS             complement(14714..16282)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978679.1"
                     /locus_tag="LJA35_RS03815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_165288116.1"
                     /sec_met_domain="DAO (E-value: 6.6e-14, bitscore: 51.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARRTTAARRGRDRKAEIVLPEPGADRFRRGDEPSVAVIGGGIA
                     GLAAATLMAERGARVTLYEKGDSLGGRLSGRRTTLADGSAVTMTRGFHAFFRQYYNLRG
                     LLRRTDPGLERLTPLPDYPLRHSGGLTDSFARVPRTPPFSALGFVALSPTFGWRDLAAM
                     DARAALPLLDVRVPEVYERFDTVTATGFLEGVRFPEAAHHLAFEVFSRSFFADPRRLSA
                     AELLLMFHIYFLGSAEGLLFDVPDEPFPQALWDPLGDYLRRLGVDVRTGTPVQGVLPRD
                     GGGADVITDTGADRHQAVVLALDTAGLRQTVAASPGLGTDAWRDGIAALRTAPPFLVSR
                     LWLDRPVDADRPGFLGTSGFDGLDNVSVLERYEGEAARWAARNGGSVVELHAYAVDPAA
                     EPKQVQDELVDRLHQVYPETREARVVDARHEWHSDCPLFEVGSHRLRPTVRTPHRWLTL
                     AGDGIRCDLPVALMERAATTGFLAANALLADRGVRGQTLWTVPRTGRSTVLRALGAAAG
                     RHSAP"
     gene            complement(16279..17019)
                     /locus_tag="LJA35_RS03820"
     CDS             complement(16279..17019)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524375.1"
                     /locus_tag="LJA35_RS03820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_165288115.1"
                     /transl_table=11
                     /translation="MTLLRDHDLARAFDHASHTYDHLTALNPGYRAGLLRSARRLALPD
                     DGAGLHLLDLGCGTGASTRALLRAAPRARITAVDASAGMLRRALAKPWPARVRFLHLTA
                     EEVGAAREDESPFDAVFAAYLFRNVTDPDAVLGSVRGLLRPGGRFAAHEYSLSGSPVHR
                     ALWSAVCSGLVVPAGTLTGDRTLYRHLRHSVVAFDTAPQFAARLRRAGLTSVRVAPVAG
                     WQTGIVHTFLARNGEPRTTEERAR"
     gene            complement(17016..18233)
                     /locus_tag="LJA35_RS03825"
     CDS             complement(17016..18233)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011026915.1"
                     /locus_tag="LJA35_RS03825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_233648203.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 6.6e-104,
                     bitscore: 346.7, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPRRTEDSGVLVLGGGAAGLSLAHRLTENGTDTAVTLVEPPDGP
                     LRPAERTWCYWGAGTDGLEEAVSASWSVLRLHGADGGSVTVDPAPFTDRMVRSADFERM
                     VHGRLARTEGARLLRGTAEAVRAVPAGAEVRCALPGGRPLTLHARRVFDSRPLPGLPPA
                     RTRLLQHFRGWFVHTDTDRFDPAVADLMDFRVPQPAHGLAFGYVLPLAPERALVEYTEF
                     SRDVLTTAAYESALGHYCRDILGLGRLTVERTEQGVIPMTDARFPRRAGHAVFRIGTAG
                     GATRPATGYTFAAVQRHSRAVAAALRDGHDRFPAPHGPRALAMDAILLRALDTGRIDGP
                     RFFTDLFRRVPAERLLRFLDGTTSLREEWGIGLRTPVRPMLRTAAEVPFLPRRSRPADR
                     TGGHTR"
     gene            complement(18475..19734)
                     /locus_tag="LJA35_RS03830"
     CDS             complement(18475..19734)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103062.1"
                     /locus_tag="LJA35_RS03830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_233644990.1"
                     /sec_met_domain="DAO (E-value: 6.6e-10, bitscore: 37.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDGHRRAADVVVVGAGLAGLACALDLCRAGWRVALLEASDGIGG
                     RMRTDRRDGFLLDRGFQVFNTSYPQVKRRVELKGLRLRPFTAGVVAHTPSGPVRLADPT
                     REPRAAGTLLPGRALSARDLTALAALTARDAVLPVSVTRRCRDRSTAAALSAAGLSDAA
                     ITGILRPFLSGVFLEDRLETSARFFHLVWRSMARGSLCLPAEGIGAVPAQLADGLPDGV
                     LRLGTPVAEITDAGVLLGDGGEMPARAVVVATDQATAAGLLADLSVPATRTVTTYYHAT
                     DSPPTAEPILMVDSTGGILNTCVLSQVAPTYAPPGTALVSTSVLGTDLPGRAQAVLRRL
                     AELYGTDTSGWEQVAARTVDGALPAMLPPWPLSRTTRLGPGRYVCGDHRATGSVQGALA
                     SGTRAAREVRADLERQGRRQ"
     gene            complement(19972..20976)
                     /locus_tag="LJA35_RS03835"
     CDS             complement(19972..20976)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978674.1"
                     /locus_tag="LJA35_RS03835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_233644991.1"
                     /transl_table=11
                     /translation="MNAHTGASDAPVGEGGTSRGGLTTGEVARRLGVAPTTVRTWDRRY
                     GLGPDAHKGGRHRRWTAEDVARLERMCALTATGLPPAEAARLARSEEGPTAPGPRSTDA
                     ARRVSGGHRSRAGSGLRLGDVRQECRGIARAALRLDAAVLDELLLAAIAEHGLVAAWTE
                     VIVPTLQAVGRKWETSGEKYVEVEHFLSWHVSGALRRATSRTVEDRPGATTVLACVPGE
                     NHTLPLEVLSAALTERGIPVRMFGGALPVESLVAAVRRTGPAAVALWSQSRTTASRPLA
                     QHVAAMEWGVRGARRRPFVLTLGPGWAGRPVAGLARPSGLAEAVAALETSVYP"
     gene            21140..21748
                     /locus_tag="LJA35_RS03840"
     CDS             21140..21748
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981393.1"
                     /locus_tag="LJA35_RS03840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_102932074.1"
                     /transl_table=11
                     /translation="MNTRTRPTTTLVPPVEETRYEEELAQGLVNADEEAFAAIYRRWGS
                     LVHTMATRSLGDTHEAEDVTQQVFVGAWRGRHGFRPERGPLGAWLVGITRRKIVDALAA
                     RTRRLSLIESAGQDVTPARLVRPAPDEVLDRVLLLEALSRLPRAQREVLCLAFYEDLTQ
                     AQIAEHTGAPLGTVKSHARRGLHRLRTAVDPGTAQEMCT"
     gene            21856..22650
                     /locus_tag="LJA35_RS03845"
     CDS             21856..22650
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325004.1"
                     /locus_tag="LJA35_RS03845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4397 domain-containing protein"
                     /protein_id="WP_102932073.1"
                     /transl_table=11
                     /translation="MTSRTTIAVAASAGACVLTLGLTGPAATAAPEQAQDTGLVSVFHG
                     IPGMTVDVYANGDELLSDFKPGTVTDPRSLDAGTYDIEVFKAGQDPDGTPALEKEVKVA
                     QGGNATVAAHLSTDGKPRLTTFTNDVSKTEAGKARLTVRHVAAAPAVDVRAGGQPLFTD
                     LTNPDEDTTSVDSGTVNADVVLAGTDTVAIGPAELTFKEGTANVVYAWGSTEDKTLSLA
                     DQTFSGLESTPHAVHAGGRGAAITPNPSDQWALWAATPERSR"
     gene            complement(23747..24457)
                     /locus_tag="LJA35_RS03850"
     CDS             complement(23747..24457)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972601.1"
                     /locus_tag="LJA35_RS03850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD family phosphatase"
                     /protein_id="WP_165288111.1"
                     /sec_met_domain="HAD_2 (E-value: 2.1e-21, bitscore: 75.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTLDHALLDWSLEAVVFDCDGTLMDSERHWQEARSRAFREHGLQ
                     PPPGFAEQALGLHYEDCGRLMAQAVHKPELAEDLTAALLDHFLALVTEEPVTMPGAARL
                     VRLLSGRLPLAVASNCPRVVVEGSLERAGLLAHFRHLVVPDAGDRVRPKPHPDVYAVAA
                     RLCGVPPRRALAVEDSLTGVEAARRASLRVLGVGPRPQGDGATRADAWLPSLDAPELLA
                     WAHALDSPQGPRTP"
     misc_feature    complement(23822..23824)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    24513..24533
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    24597..24610
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.25"
                     /tool="antismash"
     gene            complement(25123..25314)
                     /locus_tag="LJA35_RS03855"
     CDS             complement(25123..25314)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LJA35_RS03855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_146045883.1"
                     /transl_table=11
                     /translation="MTRRISSGSPPKNDTSGWSARGAITFVLTGLRMTGVPEQGLQRLI
                     VTPLSGDRAPAAAGRKNS"
     gene            25474..28140
                     /locus_tag="LJA35_RS03860"
     CDS             25474..28140
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327708.1"
                     /locus_tag="LJA35_RS03860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_233648204.1"
                     /transl_table=11
                     /translation="MGRTPGDTGTDPLGGPYLRTRFALPSRPATFLRRQRLVAHLNQAL
                     RTPLTVVNGAAGAGKTLLTADWAAGLRLPVAWLTVEAGDHLPGVFWAYVFESLRVHGAR
                     AGGTPGAPADSSGVGHGLLASLASELNALDRPVVLVLDEYDRMTSPEVAEQLEFVLHHA
                     GPGMHLVLVTRTEPLLPLHRYRASDELTEIRGSELSFTSQEARALLRLHGLQLPEHAAS
                     ALVDRTRGWAAGLRLCALAARESTDPEQYLKEFEADHSTVADFLLAEVLKRRTQEEQDL
                     LLRVSVLDRFCPDLADALTLRTDAEGLLAGLHRENAFIERLEHSWYRLHPLFREILQVH
                     LRERMPGVEAELHLRAARWLRRSGFLSETLAHGAAGGDFDLAAGALVDDLAIGQLFTGL
                     RSDALTQLFAGMGSEAESPASNLVRAAGALARRDLDHGLGRLRRAQEQLSGSDDSPGPV
                     AARLSCTLLEALAARLTGCPTRAEQAVARAEELRQDLPDHLLDEHPELTALLLTHVGSV
                     RLWEGRFDDARAALTQVTAAPPGPTTVLPRVESMGHLALLDYLNGWLGRAERKALAAVS
                     EAQRAGLPRPPGAGLGRLVLAAVAVDRQELGRARALLEETDRLPAREHDPVPTAGRALA
                     VSRLLLDDGGTHTHAAAEAAEPAVSTEASSPWAEGYAAVAHSAASLADGRPEEAVRLLH
                     GVSGDQPVCAVEAAAIQVAAGRPRAAAELLGTVRTEGRTGPAVSVGAALVRARAAQESG
                     EAAVARKLVARALLDARRERLRRPFLQAGDWIEPLLAAPPLHELAEGWLLHDRPGAHGE
                     PVRSGSSPTLLVPVELSGRERDVLRRLASMMSTEEIAADLYLSVNTVKTHLKSAYRKLA
                     VNRRGDAVRRARDLGLL"
     misc_feature    27640..27642
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 ccgcgtacgt gagcaggtgc aggtggtacc aggtctcgta gcgcatccgg cgacgtaccg
       61 cgcgcaccga ggtgtagccg acggcgagca gtatcagggc gcctgccgtg gctttgagca
      121 tctccggtag atcgaacacg atcgtgccga gttctctcaa cgcccccacc tgtgcctgtg
      181 ccgcgtagcc gaggacgatc agcaggatgt gtgccaggag caggccgatg gtccagcgcc
      241 ccgccgaggc gtgccagcgc gcggcacggt cgctgcccac ccggctctcc agccacggca
      301 cccgcgccat cagggcgacc agcagggcgc acatgtatcc gcacaggagc cccgtgatgc
      361 gccccgcacc ggtgagccag ccggccgcgc cgacgaccga gcccgtgtcc ctccaccaca
      421 gcgcgagtac ggcgatgcct ccggcccacg cggccgcctg gagcgccgcg gccggtgatg
      481 cccgccgcgg cgtggcgggg gcgcggtgcc gctccggggg cggtcggtcg gtcgcggtgg
      541 ccatggacgt ctcctcgggc aggggctgtc cactgtggcg ccgcaacctc tgagacggct
      601 ctgagccgca ccccgaccgt gacggtacga ggggcgcaga agatcttcag aggaaatcca
      661 gagggttacg ggggatgctg ggacggccat gaacacaccc agcgcagtac tgacccgtgc
      721 cgacggcacc cccgtgcgtg tcctcgtcgt cgacgacgaa cccgatctcg ccgaggtcgt
      781 caccggggcc ctgcgctacg agggctggga cgtccgcgcg gcggcctcgg cggacgccgc
      841 cgtccgcgaa gcccgcgcct tccggcccga cgccgtcgtc ctggacatca tgctgccgga
      901 ccgcgacgga ctgtcggtcc tgcgcgacct gcgcgccgag cagccgcacg tgtgcgtgct
      961 gttcctcacg gcgcgggatg ccgtcgagga ccgcatcacc gggatcaccg cgggcggcga
     1021 cgactacgtg accaagccgt tcagcctcgg ggagctcgtc gcgcgactgc gcggtctgct
     1081 gcgccgcgcc gggatgacac gcgagcgggc gaccgactcc ctgctcgtgg tcggggacct
     1141 cgaactggac gaggacgcgc acgaagtcac ccggggcggc gacctgatcg acctgtcgcc
     1201 gaccgagttc cagctgctgc gctgcctcat gcggcacgct cgtcaggtgt tgagcaagac
     1261 gcagcttctc gatctggtct ggtcctacga cttcggaggc ggtgcccacg tcgtcgagct
     1321 gtacatctcg taccttcgca agaagatcga ctcgggccgc gccccgatga tccacacggt
     1381 gcggggcgcc ggatacgtcc tgaagccggc gccccagtga ggtggccgcg ccttcatacg
     1441 ctgcgcgccc gcctgaccgc cgggctgctc gtgctgctcg ccgtcgcgtg tgccgcggtg
     1501 ggcggggcgg ccgtactgga actgaacggg ttcctcaccg accgcctcga ccagcagctg
     1561 gccgacacgg gcagcgcttt cgcggcgagt ctggagcacc cggacacgga ccacgacgac
     1621 cacgacggag acgaacgcgg cgacacccgc cgccaggccg ccgagacgct gggggtccgg
     1681 atcgcggacg gccgggtgac caacgccgcc gtggtccgac agggcgacgc atcggctgac
     1741 gtggtcaccc tcgaggtcga cgccgaggac gcccgggccc tcgcggccgt gcccacggac
     1801 ggacagggcc acagcgtcga gctgaccggc ctcggcgact accgggtgag ggcatggcag
     1861 gggcgggacg gcgacacgct gatcaccggc ctgccgctgg agccggtcga agcggcggtc
     1921 caccggctcg aactcgtcgc gggcggcgtc ttcggtctgg cgctcgtcgg tgccggcgtc
     1981 gcgggtgcgc tctgggtgcg ctggtccctg cgctccctca gccgcatcgc cgacaccgcg
     2041 acccgggtca gtgagcttcc cctcgcgagc gggacggtcg cgctgcccgc gcgcgccccg
     2101 gacacccggc cacgcagcga ggaggtcgac caggtcacca ccgcgttcaa ccggatgctg
     2161 ggccacgtgg agcatgccct gacccagcgc cagcgcagtg aggaacgtct gcgcagcttc
     2221 tccgccgacg ccagtcacga actgcgcacc cccgtggcct cggtgcgcgg tcacgccgag
     2281 ctggccctgc tccacccggg ccccctgcca cccgaggtgg gccgcgcgct ggagcggatc
     2341 gccgcggagt ccgcccggat gggcgccatg gtcgacgacc ttcttctgct cgcccgcctg
     2401 gacgccggcc gccccctgga ggacgaaccc gtcgacctga cgcggctcgt gctggacgtg
     2461 gtcgacgacg cgcgcgccgc cggtccggat caccggtggt ccctggagct gccgcaggag
     2521 ccgatcatcg tgtcgggcga ccggcaccgc cttcaccagc ttctcgcgaa cctcacggcc
     2581 aacgcccggc tgcacacacc tcccggtacc gcggtgaccg tgggtgtacg acgggacgac
     2641 gacggcacgg cctgcctcac ggtgaccgac gacgggccgg gtgtcccgcc cgccctgcgc
     2701 gaccacctct tcgaccgctt cgtccacgga gacggccccc gcggcgccga cgggggcggc
     2761 acggggctcg ggctgtccat cgtcgccgcg gtggccgccg cacacggcgg caccgcgtcc
     2821 gtcaccggcg aaccgggcac caccacgttc accgtgcgcc tgccgcgtcg accgcctggg
     2881 tagccccgcc cggcgtcgga ctgcggcgtc gcactggcca cggaccgtga ccgtcagggt
     2941 gcaccggacg tgctgaggat ccagtctgga agggaaccgg cagtgattcc gtcaggcact
     3001 ccgccgggct tccggcgcgt gccctccacc gacttcagga ggcggccgtg aatgcaacag
     3061 cgaacagcgt cgacccggtc gacgtggccc gagcggcgtt ccggtccgtg gccgccggac
     3121 atctggacca cttcacggaa ctcctccacg aggatgtcgt cttcgacgtc gtccctgtgg
     3181 gcctgcgccg gggccgacag gctgtgcggc ggtacttcga ggaggtccgc ctggccatgc
     3241 ccgatctggt gatgaccatg gaacacgccg tcggagacga ccggtacgca gcggtggaat
     3301 ggcgcatgac cggtaccttc gacggagcgc cctaccaggg gctcgccccc acgaaacggc
     3361 acacgccctg cagggtgtcg acttcgtcga agtgggcgcc ggacgcatca ggcgttcccg
     3421 aaccgtcttc gacggcgccg aactgggccg ccagatcggc ctcctgccct cccgcggttc
     3481 agccgccgac cgtgccgcga ccagggcgtt caacgtgaag acacagctca ccgaccgctg
     3541 gcgggagcgt cacgcacgtc aacgcagcca cgctccgtag ccctctgggg gtgtttccgt
     3601 cccgcgcgcg gaccggccgt cagcgcatcc cggccccggg aggccgccgg gcgggtgatc
     3661 gtggtgcttc tgtgtgctcg ggaccctgtc ctgcgggcag agtgtgcccg cgccgttccg
     3721 cgtccggcag ggcggcggcc gcctctcgtt ctcgggccgc ctgctcggga tgacgacgct
     3781 gccagtaggg gttgtcgtgc gacagctcgc tggacgcccg gccgtacatg ccgaacgtgg
     3841 cgatgaccag tcccatgacg aagctgaaga tcacgttggt catcccgaag tcgaggacat
     3901 tggcgcgacg gtccagtacg aagacgtgga agaacccgct caggacgaag agcgcgccga
     3961 ccgtcatgtt gaggaccgag gcgaagttgc cgccgaccgc cgcgccggcg agcagcgtca
     4021 gaccgacgac ggcggagatc acgctgagcg cgacgtcggt ggtcatgccg gcgatcgtgt
     4081 cgcccgcggt gtcgaacggg ctcagcgcgt ccgcgaagcc gagacatgcg aagaccagca
     4141 ggaccagccc gcagaagccc gcgccgtagc ggtagacggt ggccagatgg tgatcgactg
     4201 gcatttcgtc ttttagcctc atgatcgttg tttccgcgtg tgcgctcgct tcggatgtgt
     4261 gtccggcgac agggccccgg gccggtaccg aggcgtgcat ccaccgcggg ccccgcgtgc
     4321 gaagtacgca gtgacgatct ggtgcgcgca gcggccgcac cgcccggcct gccggcagga
     4381 gacgctcatg cacgaggtgg cgacggacca ggcgttcgac gcgcgcggcc ggcggcaccg
     4441 cgacggcgtc ggtgaccgtc cggcgcggga gcccgtgata cggcacgtac cgctcacctg
     4501 gcgcggtctg ggtctggaca cgatggcgtc gctgctggtg gagtccttcg cccgcctcgg
     4561 cagtcgctgc ttcgcggccc gttgccagtg gccccgcctg catccgctga acgaacgcgc
     4621 gctgggcgcg gtgacgcacc atccgctgat catggcggag tccgcccggc agctcgccct
     4681 cgcactggag tacggccgtc ctccgggaac ggttcgtgct cggctcgaac ccgtctcggt
     4741 ccgcctggga ctgcggctgc ggtcgtggcc cgtggagcgg ggcggcgcca ccgacgtgga
     4801 cgtgcggatg agcgtgagcg atctggtgac cgtggccggt cggcccgtgt cccatcgcgt
     4861 cacggccgag ttcctgcaca cggggaaatc cttcgggtcg tgcaccatgc ggttcgcccg
     4921 cccggcgggc tcggcggtac ccgtggaggg agcaccgctt ccgggtctgc tgcatccccc
     4981 ggcggccgcg gtcggtgcca cggccgacgg tgacgtgatg ctggcacggg gccctcgggg
     5041 acgactggtg accgccccgc gcgaccccgg gcacccggtg ctcctggccg gccggccggc
     5101 gcgcatgccc ctgttggcgg tcctggaggc ggggcggcag gcggttctgc tggagagtgg
     5161 gatgacggct gccgcggtga tcgggttgcg ggcggacgtg tgcgcaccgg tgccgtcgcg
     5221 cggtgccctg atcgagacct cggcggaacc gggcggatcc cggttcctgg tcacggcctc
     5281 gggccgcccc gccgcgacgg gcgcggtgac gttgtggagc aagtgatcgg cagtcccggc
     5341 atggtgtggt ggacggaccg gaaggaaaga gccgtggcgg cgaacggacg gcaggaccag
     5401 gaacgactgc tctgtctggt gaccggcgcc tccgggtacg tcggcggacg cctcgtgccg
     5461 gagttgctgg gggccggtca ccgggtgcgg tgtctggccc gcaccccggc caaactccgt
     5521 gaccagccct gggcgtccga tgtcgagagc gtgcggggag acgtcaccga cccgcgttcc
     5581 gtcgccgagg ccatgcgcgg cgtcgatgtc gcctactacc tggtgcatgc cctcggggcg
     5641 ggcgccggct tcgaggacac cgaccgtcgc gcggcgcgcg tcttcgctca gcaggcgtac
     5701 gaggcgggcg tgcggaggat cgtctacctg ggtggtctga ctccgcgagg cgttcccgag
     5761 cgcacgctct cccctcatct gcggtcacgc gcggaggtcg gccgcatctt cctcgacgcc
     5821 cccgtgcccg ccaccgtgct gcgggccgcg gtggtcatcg gatcggggtc ggcgtccttc
     5881 gagatgctgc gctacctgac cgagcggctt cccgtcatgg tgacgcccag ctgggtgcac
     5941 acccgcaccc agcccatcgc gatccgcgac gtgttgcact acctggtcgg gtcggccacc
     6001 atgccggaca acgtcgaccg cgccttcgac gtcggagggc cggacgtgct cacctaccgc
     6061 gagatgatgc gccgctacgc caccgtgagc gggctccggc ggcggatcat cgtgcccgtt
     6121 ccggtgctca ctcccgggct gtccagccac tgggtcggcc tcgtcacgcc ggtaccggcc
     6181 gccctcgccc ggcccctgac ggagtccctg cgtcatgagg tggtgtgcca ggagcacgac
     6241 atcgcccggt acgtccccga cgctcccggc cggcccctgc cgttcgacga agccctggcg
     6301 ctggccctgc gtcgggtccg ggaggcccag gtggccacgc gctggtcgtc cgcctcggtc
     6361 cccggagcgc ctagtgatcc gctgcccacc gaccccgact gggccggcgg cagtctgtac
     6421 caggacgagc gggaactgcg ggtcgacgcg tctccggaag ctctgtggaa agtggtggag
     6481 ggcatcggcg gggacaacgg ctggtactcc ttcccgctgg cctgggccgt ccgcggctgg
     6541 ctggaccggt tcgtcggcgg tgtcgggctg cgccgcggcc ggcgggacgc ccagcacctg
     6601 cgggtcggcg actcgctgga cttctggcgg gtcgaggaga tcgaaccggg acggctgctg
     6661 cggctgcgtg cggagatgcg gctgccggga ctggcgtggc tggagatgca cgtcgagacg
     6721 gacgcggaag gccgtacccg ctatcggcag cgtgccctgt tccatccgcg cgggctgctc
     6781 ggccacgcct actggtggtc cgtgttcccc ttccatgccg ttgtcttcgg cggcatggca
     6841 cgcaacatcg gtcaggccgc cgtcaagggt atgaccaccc gcaggagtga tgaccgatcg
     6901 tggcgcatcc ggcgtcgacg cgccccgcga agtgtggagc actgagcctt cgtccaagca
     6961 ccactgcgcc aggagtgacg ccatgaccgt cgcggtcgtc ctgttcacct cggacctgcg
     7021 tctgcacgat catccgcctc tgcacgccgc gctcgaggcg gcggacgagg tggtgccgct
     7081 gttcgtcctc gacgccggca tccacgcggc ggggttcgac gcccccaacc gcagggcctt
     7141 cctcgccgac tgtctcagcg acctcgactc ctcgctgcgc caccgcggtg gccggctcgt
     7201 ggtccgcaac ggaccggtcg tccgggaggt ccgcgcggtc gccgcccagt gcggggccgc
     7261 cgaggtgcac gtggccgcag gtgtcaccgc gtacgcccag cgccgggagg aagggctgcg
     7321 cgaggagctg ggcgaggacg gcgtcgcact gcgcgtgcac gagacggtga tcaccgccgt
     7381 cgccccgggg gcggtgacgc cctccggctc ggaccacttc gcggtgttca ctccctactt
     7441 ccgccgctgg tcgcaggtct cgtcgagaaa gcccctggcc gctccgcgca ccgtgcgggt
     7501 accggacgga gtccgcggcg agccgctgcc cgaccgcgcg gacgtggccg gtgcctcgcc
     7561 cggtcttccg gccggagggg agacggccgg gcgcgaccgg ttcgcacggt ggtcgcgctc
     7621 cggactgtcc cgctacgagg agcggcacga cgacctcgcg gacgatgcca catcccggct
     7681 gtcgccgtac ctccacttcg gtgcgctctc cccgctggaa ctcgtccacc gggcccgcgc
     7741 gcacggcggg cccggcgcgg aggcgttcgt ccgccaggtg tgctggcggg acttccacca
     7801 ccaggtgctg gcggcccggc ccgaggcgtc ggtgaaggac taccgcaccc ggcacgaccg
     7861 ctggcgtgac gaggaggacg ccgccgagga catcgccgcc tggcggggcg gacggacggg
     7921 ttacccggtc gtcgacgcgg ccatgcgcca gttgcgtcac cagggctgga tgcacaaccg
     7981 ggcacggttg ctggtggcga gtttcctgac caagacgctg tacgtcgact ggcggatcgg
     8041 cgcccggcac ttcctggacc tcctcgtgga cggcgatgtc gtcaacaacc agctcaactg
     8101 gcagtgggtc gccggcaccg gcaccgacac ccgcccccac cgcgtcctca atccgctcgt
     8161 ccaggccaag cggttcgacc cggacggcat ctacgtacgg cgctgggtcc ccgaactcag
     8221 gagcgtgacc ggcaggaagg tgcacgaacc ctggcgcctg gcggcagcgg aacgaggaga
     8281 actcgactac ccggacccgc tcgtcgacct cgccgacgga ctcgcgcgct tcaagcacgc
     8341 ccgcggccgg gactgagggg acgcgtcgtg cactggctct tcggtgacca actgggtccg
     8401 cacttcctca cgccgggcga agggggaccc ggaccggaaa ccccgttgct catgatcgag
     8461 gcgcgctccg tcttccggcg gcgccgattc caccgggcca aggcccactt ggtgctgtcc
     8521 gcgatgcgcc accgcgcggc cgaactgggc gaccgcgtca cgtacgtgcg tgccgacacc
     8581 taccgtcagg gcctggaacg ggcggcgcgc gggcgcccgg tcggcgtcca ccaccccacc
     8641 tcgcacgcgg ccctgcgcct ggtgcgtacc ctgcccggag tgacggtggg acccgcccgc
     8701 ggcttcctcg tgccgatggc cgacttcgcc gcctgggccg acggccacgg cggcaggcgc
     8761 ctgcggcagg aggacttcta ccgctgggta cgccgcgggc acgatctgct catggacggc
     8821 gagcagcccg cggcaggacg gtggaacctc gatcacgaca accgggaacc cccgccccgc
     8881 gaggccacct cactccaggt cggccgcccg taccggcccc gcgaggacga catcgacgaa
     8941 gaggtccgcc acgacctcga ccgctgggag cgcgagggcg acgtctcctt cgtcggacgg
     9001 gacgggcccc gcctgttccc cgccacccgg gcggaggcgc gacgtgcact gcggcgtttc
     9061 gtcgaacgcc ggctcgccac gttcgggccc tacgaggacg ccatgctcgc cgccgacccc
     9121 gccatgagcc acagcctcct ctcgtcctcc ctgaacctcg gcctgctcga cccggccgag
     9181 tgcgtcgaac gggcggagcg cgcctggcgc gcaggtctgg cgccgctgaa cagcgtggaa
     9241 ggcttcgtgc ggcagatcgc cggctggcgc gagtacgtct ggcaggtgta ctggtacttc
     9301 ggcgaggact accgacgctc caacgcgctc gggcacaccg caccgctgcc ggactggtgg
     9361 agcgtcctgg acgcggacgc cgtgcgggcg aactgcctgc gcacggtctt ggcccaggtg
     9421 cgggacacgg gctggacgca ccacatcccc cggctgatgg tgctcggcag tcacgcactc
     9481 cagcggggct gggaacccgc cgccgtcacg gactggttcc accgctgctt cgtggacggc
     9541 tacgactggg tcatgctgcc caacgtcgtc ggcatgtccc agtacgccga cggcggccgg
     9601 atgaccacca agccctacac gtcgggcggc gcgtacgtga accgcatgag cgacctctgc
     9661 ggcccgtgcg tctaccggcc cggcgaccgc accggcgagc gcgcgtgtcc gtacaccgcc
     9721 ggctactggg cgttcctcga ccggcaccgg gaactgctgg ccggcaatca gcgcgtggcc
     9781 cggccggtac ggcagttgga ccggctcggc gaccttccgg aggtgctcga acaggagcat
     9841 gcgcggggtg acacaccgcc gtgaacctct cactgatgcg ccggctgggt gaagtcggac
     9901 cggacccggc tccgcagcgg gcagaagtca gtgcatccgc aacagggcat ccggtggaag
     9961 cagtggcgtg cggacaacca agagtgagaa ggggctgcgc atgcctggac tgccgccgat
    10021 ggtggcccca ccggccgaac gggtcgacga ccccctcacc gcgtccggcg cggcgaaagc
    10081 ggtcggcacc gtcctcgagg aggtactgga cgaacgactg cgccattccc gttccgtcga
    10141 ccccgtcttc gcccgggagc tggccgaccg tctcgcggcg ctgaccgccc ggggcggcaa
    10201 gcggctgcgt accgcgttcg cccactgcgg ctggcgcgcc gcgggcggct cgggagacgc
    10261 cacggccgtc ctgcgaacgg gagccgcact cgagctgctc caggcgtgcg ctctcgtcca
    10321 cgacgacgtg atggacggct cggtgcagcg acgcggcgca ccggccctgc acgtcgacct
    10381 ggcccgcagg cactgggcag cgggcatgca cggctcgtcg gagtccttcg gcacctccgc
    10441 cgccgtcctg accggtgacc tggccctcgc ctgggcggac gacctgctgg ccgagacggc
    10501 actcggtacg ccgcacggca cgcgcctgca cggcgagtgg cgggcgatgc gcaccgagat
    10561 ggtcgccggg cagtaccgcg acctgcacgc ccaggccgcc cggtcctccg gcgtcgacga
    10621 ggcgctgacc atcgccacct tgaagagcgc cctgtacacc gtcgcgcggc ccctcgcgct
    10681 gggagctgtg ctggccggag ccgacgggga cgcactggac gcgctgcggg cggccggccg
    10741 gtgcgccggg ctggccttcc aactgcgcga cgacctcctg ggcgccttcg gcgaccccac
    10801 gctgaccggg aaaccggccg acgacgacct gcgctcccgc aagctcacct acctgctcgc
    10861 cgtcgccgtc cggctcgccg atgccgccga tgaccacttg tcggccgcgg cgctggctcc
    10921 ggacgcggac ccgaagtccg acagggccgt ccggcaggtg cggtccgcgc tggtgcgcac
    10981 cggtgcccgg gacctggtcg aggcgaagat cggggagctg acggacatga gcctcgcgca
    11041 cttcgaccgc tgcggcgcgc gcccggccgt gcggcacgag ttcgccgcgc tggtcgggcg
    11101 ggcaacgggc gcggtcccgc gtggtgacgg ggaggtcgcg tgaagcgggt accggggccg
    11161 accgaccacg tcgtcgtggt cggggccggg ctgtccgggc tggcgtgcgc cctgcacctg
    11221 ctgggtgcgg gccgcagggt caccgtcgtc gaacgggacg ccggccccgg cggccgggcc
    11281 ggccgggtgc ggcgggccgg ctacgcgatg gacaccggtc ccacggtgct gaccatgccg
    11341 cacctggccg acgaggcgtt cgccgccgtc ggggacagcc tccaccgccg cgtcgagctg
    11401 acggctctgg atccggccta ccgggcctgt ttcgcggacg ggtcctcact cgacgtgcac
    11461 accgacggcg aggcgatgga ggccgaggtg cgccgcttcg ccggacctgc gcaggcggcc
    11521 ggttaccgcg acctgcggca gtggctcgaa cggctgtacc gggtgcagat gcgccgtttc
    11581 atcgacacca acttcgactc ccccctccag ttgctgcacc cggacctggc ccggttggcg
    11641 gcgctggggg gattcggacg cctggacggc cgcatcggcc gcttcctgtc cgacgagcgc
    11701 ctgcgccgcg tcttctcctt ccaggcgctg tacgccgggg tggcccccgc ccgcgcactc
    11761 gctgcctacg cggtgatcgc ctacatggac acggtggccg gcgtctggtt ccccaagggc
    11821 ggcatgcacg cactgccccg agccatggcc gacgcggcgg cggacgcggg tgccgatctg
    11881 cgctggaggg ccgaagtgga cacgctggag cggtccgcgg gccgggtacg gtccgtccgc
    11941 ctggcctccg gcgagcgcat cgcctgcgac gccgtggtgc tgacgtgcga actgcccgcc
    12001 gcctacgggc tgctgggacg ggcaccccgg cgtccggtac ggctgcggca ctcaccgtcc
    12061 gccgtgatcc tgcacgcggg caccgaccgc acctggccgc acctcgccca ccacaccatc
    12121 tccttcggcg ccgcgtggga gcgcaccttc gaggagctga cccgtaccgg agaactgatg
    12181 agcgacccct ccctgctgat cacccgaccc accacccacg acccggccct ggcaccgccc
    12241 gggcgccacc tccactacgt cctggcgccc tgtcccaaca cccacgtcgg tccggaggca
    12301 gccgcgtggc gtgacctcgg cccgcgctac cgcgacagcc tggtcggcgt actggaaaag
    12361 cgggggctgg aggggttcgc ggacagtgtc caggaggagc tcctggtgac gccgctcgac
    12421 tgggacgcgc agggccatgc ggcgggcagc cccttctcgg tctcccacac cttcgcccag
    12481 accggcccct tccgcccgcg caacctcgta cgagggctgg acaacgtggt gctcgcgggc
    12541 tgcgggacaa acccgggagt cggcgttccg accgtactgg tcagcggcaa actcgccgcc
    12601 gcgcgtgtca ccggcggcgc ccgctcccgg cccgcccgaa cgcgtcggtc cccggccgtt
    12661 cccgccacgt atcccgcccc cgccccggca ggtaccgatg agccgtcgtg aactggacgc
    12721 ggcggggatc accgatcccc tgctgcgcgc cgcctacacc cggtgtcgcc ggctcaacgc
    12781 ccgccacggc aagacctact tcctggccac ccgcctgctg ccactcgaac gccgctccgc
    12841 cgtgcacgcc ctgtacggct tcgcccgctg ggcggacgac atcgtggacg acctcgaccg
    12901 gcaccgcacg cccgaggaac gcgaccggtt gctgcggcgt ctggagagcg acctggccga
    12961 cgggctgctc acccgggcgg gccgcgaacc cgtggtcagg gccgtggcgg acaccgccgg
    13021 ccggtacggc atcgatcatg cgctcttcgc cgacttcctg tcctcgatgc gggccgacct
    13081 gaccgtcacc cactacccga ccttcgccga tctgcaggga tacgtgcacg gttcggcggc
    13141 ggtcatcggc ctgcagatgc tgccggtcct cggcacggtc acggcccggg aggaggcagc
    13201 gccgcacgcg gcggcgctcg gcgtggcgtt ccagctcacc aacttcctgc gcgacgtcgg
    13261 cgaggatctc gaccgcggcc gcgtctacct gcccggtgat ctgctggccg cgcacggcgt
    13321 ggaccggccc ctgctggagt ggagcaggcg taccgggcgc cgcgaccgcc gcatccgggc
    13381 cgctctcatg gcggcggagg ccatgacgcg gcgcgtgtac cggacggccg agccgggcat
    13441 caccatgctc gatccgcggg tgcgtccctg catccgtgcc gcgttcaccc tctacggcgg
    13501 gattctcgac gcgatcgccg agcaggatta cagcgtgctg caccgtcgtg cggtggtgtc
    13561 gcgtcggcgt cgggcggcaa cggccgctgc cggggtgctg cgcgtagccg gtgcccggtt
    13621 gcgtgctcgt acggaggacc gcgtggcacg ggcaggagcg tcggcagtcg aacggaaggg
    13681 tccggtgcgg tgagtggtcg agggaacggc aagcggtggt cgccaccctt gcgccgacgt
    13741 gcttccggtc cccactgggc ggctcagact ccgacctggc gccaggcacg tcccgcgctc
    13801 atcgccgacg cgctcaagag ggcgtccgcc cgtccgtccg gcaactggtt cgtggtcggc
    13861 gcctcccgga acgtgcgcgc gggcgaccgg ccctacggcc ggacggtcgg tggtgtggag
    13921 gtcgtgctgt ggcggtcgga ggacggcgag ccccatgccg gtgagggcag ctgtccgcac
    13981 ctgggcgctc cgctgcgcga cagccgggtg gtgtgcggca cgctggtctg ccactggcac
    14041 gggctcgccc tggacggttc cgcgtccgcc ggctggcggc cgttccccgt gcacgacgat
    14101 ggcgtactcg tctgggtgcg gctggacgag gtgggcggcg aggagcccgg cgagcggccc
    14161 gtcgtgcccg cccggcccgt gacgggccgt ggggtggacg cggtgttcac ggcggtgggg
    14221 cggtgcgaac cgcaggacgt ggtggccaac cggctcgatc cgtggcacgg ctcgtggttc
    14281 catccgtact cgttcgtcga cctctcggtg gtgcgtgagc cgcaggggga cgaggacgac
    14341 gccttcgtcg tcgacgtctc cttccgggtg gccgggcggc tcgtggtccc ggtgcgggcc
    14401 gagttcaccg cgccggagcc gcgcacggtc gtcatgcgca tcaccgacgg ggagggcgcc
    14461 acgtccgtgg tggagacgca cgcgacgccg ctgaccgggc cggaccacga gcgtccgcgc
    14521 accgccgtgg tcgaggcggt cgtcgccgcc tcggaccggc ccggcttcgc cgtggcccgg
    14581 gccgcggccc ccgtgctgcg cccgctgatg cgccgtacgg ccggacggct gtggcgcgac
    14641 gacctggcct acgccgaacg gcgctggacg ctgcgcagca ccggtcggtt tcccggctga
    14701 ggtcggccgc cggtcagggc gccgagtggc gccctgcggc ggccccgagc gctcgcagca
    14761 cggtcgaacg cccggtccgg ggaaccgtcc acagggtctg gccgcgcact ccacggtcgg
    14821 cgagcagggc gttcgcggcc aggaagccgg tggtggcggc ccgttccatg agggcgacgg
    14881 gcaggtcgca gcggattccg tcgccggcca gggtcagcca ccggtggggg gtgcgcacgg
    14941 tggggcgcag ccggtgggag ccgacttcga acagcgggca gtccgagtgc cactcgtgcc
    15001 gggcgtcgac gacgcgcgcc tcacgggttt ccgggtacac ctggtgcagc cggtcgacga
    15061 gttcgtcctg cacctgcttc ggttcggccg ccgggtccac ggcgtaggcg tgcagttcca
    15121 cgaccgatcc cccgttccgc gcggcccagc gggcggcctc gccctcgtac cgctccagga
    15181 cgctgacgtt gtccagtccg tcgaagccgc tggtgccgag gaagccgggc cggtcggcgt
    15241 cgaccggccg gtcgagccag agccgcgaga cgaggaacgg cggcgcggtg cgcagggccg
    15301 cgatgccgtc ccgccaggcg tcggtgccca ggccgggtga cgctgcgacg gtctgccgca
    15361 gccctgcggt gtcgagggcc agcaccaccg cttggtggcg gtcggcaccg gtgtccgtga
    15421 tcacgtccgc tcccccgccg tcgcgcggaa ggaccccttg cacgggggtt ccggtgcgca
    15481 cgtccactcc gaggcgccgg aggtagtcgc ccagtgggtc ccacagtgcc tgggggaagg
    15541 gttcgtccgg tacgtcgaag agcaggccct cggccgatcc gaggaagtag atgtggaaca
    15601 tcagcagcag ttccgcggcg gacagccgcc gcggatcggc gaagaagctg cgggagaaca
    15661 cttcgaaggc caggtggtgc gccgcttcgg ggaagcgcac gccttccagg aagccggtgg
    15721 cggtgacggt gtcgaagcgt tcgtagacct cgggcacgcg cacgtcgagg agcggcagtg
    15781 cggcccgcgc gtccattgcg gcgaggtccc gccacccgaa ggtgggactg agcgcgacga
    15841 aaccgagcgc gctgaacggc ggggtccgcg ggacgcgggc gaagctgtcg gtcagaccgc
    15901 cgctgtgccg cagcgggtag tcgggcagcg gggtgaggcg ctccaggccg gggtccgtgc
    15961 ggcggagcag tccgcggagg ttgtagtact ggcggaagaa ggcatggaac cctcgggtca
    16021 tggtcacggc gctgccgtcc gccagcgtgg tgcgccggcc ggagagccgg ccacccagtg
    16081 agtccccttt ctcgtacagg gtcacgcggg cgccgcgttc ggccatgagc gtggccgcgg
    16141 ccagaccggc gatcccgccg ccgatcaccg ccacggacgg ctcgtcaccg cgtcggaatc
    16201 ggtccgcacc gggttcgggg aggacgatct cggccttgcg gtcgcggccc cgtcgggcgg
    16261 cggtggtacg gcgggcggtc accgggcgcg ctcctctgtc gtcctgggct cgccgttgcg
    16321 ggcgaggaag gtgtgcacga tgcccgtctg ccatccggcg acgggggcga cgcgcaccga
    16381 ggtcaggccc gcccgcctca gccgggcggc gaactggggt gcggtgtcga aggcgacgac
    16441 gctgtgccgg agatggcggt agagggtgcg gtcgccggtg agcgtgcccg cggggacgac
    16501 gagcccgctg cacaccgccg accacagggc ccggtgcacc ggtgagccgc tgaggctgta
    16561 ctcgtgtgcg gcgaagcgtc cgcccggccg caggagtccg cggacgctcc cgaggaccgc
    16621 gtccgggtcg gtgacgttgc ggaacaggta ggcggcgaag accgcgtcga aagggctctc
    16681 gtcctctcgg gccgcaccga cttcctcggc ggtcaggtgg aggaagcgca cgcgtgcggg
    16741 ccacggtttg gcaagtgctc ggcgcagcat gccggcggag gcgtccacgg ccgtgatccg
    16801 ggcccgtggg gcggccctga gcagggcccg ggtggaggcg ccggtgccgc atccgagatc
    16861 gagcaggtgc agtccggcgc cgtcgtccgg gagcgcgagg cgtcgggccg agcgcaggag
    16921 gccggcgcgg tagccggggt tgagggccgt gaggtggtcg taggtgtggg aggcgtggtc
    16981 gaaggcgcgg gccaggtcgt ggtcgcgcag gagcgtcatc gggtgtgtcc tccggttcgg
    17041 tcggcgggcc gggagcggcg cgggagaaag ggcacttcgg ccgcggtgcg cagcatcggc
    17101 cgaacggggg tgcgcagccc gatgccccac tcctcccgga gcgaggtcgt gccgtcgagg
    17161 aacctcagca gacgctcggc cgggacccgg cggaacaggt cggtgaagaa gcgcggcccg
    17221 tcgatgcgac cggtgtccag ggcgcgcagc aggatcgcgt ccatggccag tgcccgtggc
    17281 ccgtgcggtg ccgggaagcg gtcgtgtccg tcacgcaggg cggcggcgac ggccctgctg
    17341 tggcgttgca ccgcggcgaa ggtgtagccg gtggcgggac gagtggcacc gcctgcggtc
    17401 ccgatgcgga acacggcgtg cccggcgcgc cgtggaaagc gggcgtcggt catggggatg
    17461 acgccctgct ccgtccgttc cacggtgagc cggccgagtc cgaggatgtc gcggcagtag
    17521 tgcccgagtg ccgactcgta cgccgcggtg gtcagcacgt cgcgggagaa ctcggtgtac
    17581 tccacgagcg cccgctccgg cgccagcggc agtacgtagc cgaaggcgag cccgtgggcc
    17641 ggctgcggaa cccggaagtc catcagatcc gcgaccgcgg gatcgaaccg gtcggtgtcg
    17701 gtgtgcacga accagccacg gaagtgctgg agcagccgcg tacgcgccgg cggcagaccg
    17761 ggcagcggcc gcgagtcgaa gaccctgcgg gcgtgcagcg tcaggggccg acctcccggc
    17821 agcgcgcacc ggacctccgc gcccgcgggt acggcgcgca ccgcttccgc cgtccctcgc
    17881 agaaggcgcg ctccctccgt acgggccagg cggccgtgga ccattcgctc gaagtccgcg
    17941 gagcgcacca tgcggtcggt gaacggggcc ggatcgacgg tgaccgaacc gccgtccgcg
    18001 ccgtgcagac gcagtacgga ccaggaggcg ctgaccgcct cttcgaggcc gtcggtgccc
    18061 gcgccccaat agcaccaggt gcgctccgcg gggcgcagcg ggccgtccgg cggctccacc
    18121 agggtcacgg cggtgtccgt gccgttctcc gtcagccggt gagcgaggct gagaccggcc
    18181 gcaccgccac cgaggacgag gacgcccgag tcctcggtgc ggcggggtgt caccacggtc
    18241 gccgttcgac gaccgggctt ccgtcggagc ccgggtgccg cggcccgccg tgcgcctcgg
    18301 agccggtggc cggcggtccc ggacgggctc ctgccgctcc tgccaccagg acacgcacgg
    18361 caagcacacc cctcagatcc acgtttcacc cctcagtacg gacagcgatt ccgtccggtc
    18421 gccatggctt cgggaccgag gccgtcggtg gatgcggccg ggcacaccac ttcatcactg
    18481 gcgtcgcccc tgccgttcca gatccgcccg tacctcccgc gccgcgcgcg tacccgatgc
    18541 cagggcaccc tgcacggagc cggtcgcccg gtggtccccg cacacgtacc tcccggggcc
    18601 gaggcgggtg gttcggctca gcggccacgg cggaagcatc gcgggcagcg cgccgtcgac
    18661 ggtgcgggcg gccacctgct cccagccgct cgtgtcggtc ccgtacagct cggccagccg
    18721 ccggaggacc gcctgtgccc tgccggggag gtccgtgccc agcacggagg tggagaccag
    18781 tgcggtgccg gggggcgcgt acgtgggagc gacttggctg aggacgcagg tgttcaggat
    18841 ccctccggtg ctgtccacca tgaggatcgg ttcggccgtc ggcggactgt cggtggcgtg
    18901 gtagtaggtg gtgacggtgc gcgtggccgg aacggacagg tccgcgagca ggccggcggc
    18961 ggtcgcctgg tccgtcgcca ccacgaccgc ccgggccggc atctcgccac cgtcgccgag
    19021 cagcactccg gcgtccgtga tctccgcgac gggcgtaccg aggcgcagga cgccgtcggg
    19081 caggccgtcg gcgagctggg ccggtacggc gccgatgccc tcagccggca ggcacaggga
    19141 cccgcgggcc atgctccgcc agacgaggtg gaagaaccgg gcagaggtct cgagccggtc
    19201 ctccaggaag acgccggaca ggaacggccg cagaatgccg gtgatcgcgg cgtccgacag
    19261 tcccgccgcg gacagtgctg ccgcggtgga gcggtcccgg caccggcggg tgacggagac
    19321 gggcagaacg gcgtcgcgtg cggtgagtgc cgccagcgcg gtcagatcgc gggccgacag
    19381 ggcccgcccc ggcagcagcg tcccagccgc tcggggctcc ctggtcgggt cggcgaggcg
    19441 gacgggcccg ctcggcgtgt gcgccacgac gcccgcggtg aacggcctca gtcgcaggcc
    19501 cttcagttcc acacgccgct tcacctgcgg ataggaggtg ttgaacacct ggaacccacg
    19561 gtccagcagg aagccgtccc gccggtccgt gcgcatccgg cccccgatac cgtcggacgc
    19621 ctccaggagt gccacccgcc atccggcacg gcacaggtcg agggcgcagg ccaggcctgc
    19681 cagccccgca ccgacgacga ccacgtccgc tgcccggcga tgtccgtcgc tcatctgtct
    19741 cctcactcga cgtcatgtcc gtgctgtcca ggcgctgcag gccgaccgtt cggcccctcc
    19801 gcctctgccg acgtcccaga ccgttcggca cgggccgggg accgaaaccc ggtgcgagtc
    19861 gcggcgaaac gcccgccggc cgacgaccgg gccacgacca ccaggtcagc ggaccacgtc
    19921 acccggccga tgcccagccg ccacgacgaa ggacagtcgg acgacaacac ctcacgggta
    19981 caccgacgtc tccagagcgg cgaccgcttc ggcaagcccc gacggacgcg ccagaccggc
    20041 caccggtcgg cccgcccatc cgggtcccag ggtgaggacg aagggccgcc gccgggcccc
    20101 gcgcacgccc cactccatgg cggccacgtg ctgggccagc ggccggctgg cggtggtacg
    20161 ggactgcgac cacagcgcca ccgcggccgg cccggtcctg cgcaccgctg cgacgagcga
    20221 ctcgacgggc agcgcacctc cgaacatccg caccgggatt cctcgctccg tgagtgccgc
    20281 cgacagtacc tccaacggca gcgtgtggtt ctccccgggc acgcaggcaa gcaccgtggt
    20341 ggcaccgggg cggtcctcga ccgtgcggga tgtggcgcgt cggagcgccc ccgacacgtg
    20401 ccaggacagg aagtgctcga cctcgacgta cttctcgccg gacgtctccc acttgcggcc
    20461 gacggcctgg agcgtgggca cgatcacctc ggtccaggcg gcgaccagcc cgtgttcggc
    20521 gattgcggcg agcagcagtt cgtccaggac ggcggcgtcc aggcgcaggg cggctctcgc
    20581 gatcccccgg cactcctgtc gcacgtcgcc cagtcgcaag ccgctccctg cccggcttcg
    20641 gtgcccgccg gaaacgcgtc gggccgcgtc cgtacttcgg ggccccggcg ctgtcgggcc
    20701 ctcctcgctg cgcgcgagcc gggccgcctc ggccggtggc agcccggtcg ccgtcagggc
    20761 gcacatccgt tccagcctcg ccacgtcctc cgccgtccag cgtcgatgcc gtccaccctt
    20821 gtgcgcgtcc ggccccagtc cgtaccggcg gtcccacgtg cggaccgtgg tgggcgccac
    20881 ccccagacgc cgggccacct cgccggtggt caacccgcct cgactcgtac cgccctcgcc
    20941 gaccggggcg tcactggctc ccgtgtgcgc gttcacaccc ccactatacg acgcacaaac
    21001 gacgcgtgtt gcctgcgtcg tttgttcgcc ccaacactgg gaccacgcac gaggcagcca
    21061 cgccgggcag accggcgacg tgccgctcgg cggacggccc ctcccgtccc ccgtacaacg
    21121 cacggcagga ggaacggcca tgaacacgcg cacacgaccg accaccacct tggtcccgcc
    21181 cgtggaggag acgcggtacg aggaggagct ggcgcagggc ctcgtgaacg ccgacgagga
    21241 agcgttcgcg gcgatctacc ggcgctgggg atcactcgtg cacaccatgg ccacccggtc
    21301 cctcggcgac actcacgagg ccgaggacgt gacccagcag gtcttcgtcg gcgcatggcg
    21361 cgggcggcac ggtttccggc ccgagcgggg cccactcggc gcctggctcg tcggcatcac
    21421 gcgccggaag atcgtcgacg cgctggccgc caggacacgg cgtctgtccc tgatcgagtc
    21481 ggccggacag gacgtcacgc ccgcccgtct cgtccggccg gcaccggacg aggtactcga
    21541 ccgcgtactg cttctggagg ccctgtcccg actgccccgg gcccagcgag aagtcttgtg
    21601 cctggccttc tacgaggacc tgacacaggc ccagatcgcg gaacacacgg gggcgcccct
    21661 gggcacggtc aagagccacg cccgccgcgg cctgcaccgg ctgcgcacgg cagtcgaccc
    21721 gggcaccgcg caggagatgt gcacctgacc ggaaaggagc ggagacggcc ggggcgcatc
    21781 catggcaccg gtcacccgcg aaacacctct gagactgccc agcaggcgga atctccccaa
    21841 ggagggctga tccacatgac ttcccgcacc accatcgccg tcgccgcctc ggccggggcc
    21901 tgcgtcctga ccctcggcct gaccggaccc gccgccacgg ctgctccgga acaggcgcag
    21961 gacacgggcc tggtgtccgt cttccacggc atccccggga tgacggtcga cgtctacgcc
    22021 aacggcgacg aactgctcag cgacttcaaa cccggcacgg tgaccgatcc ccggtccctc
    22081 gacgcgggga cctacgacat cgaggtcttc aaggccggtc aggatcccga cggcacaccg
    22141 gccctcgaga aggaggtgaa ggtggcccaa ggcggcaacg cgaccgtcgc cgcccatctc
    22201 tccacagacg gtaagccccg gctgacgacg ttcaccaacg acgtctcgaa gacggaggcc
    22261 ggcaaagcgc gcctcacggt acgccacgtc gcggccgcgc ccgccgtgga cgtacgggca
    22321 ggcgggcagc ccctgttcac cgacctgacg aacccggacg aggacaccac gtccgtcgac
    22381 tcgggcaccg tgaacgccga cgtggtgctc gccggcacgg acaccgtggc catcggaccg
    22441 gccgaactca cgttcaagga gggcacggcc aacgtcgtct acgcgtgggg cagcaccgag
    22501 gacaagactc tgtctctggc cgaccagacc ttcagcggcc tggagtcgac accccacgcg
    22561 gtccacgcgg gcggcagggg cgcggcaata actccgaacc cgtccgacca gtgggcgctc
    22621 tgggccgcga cgccggagcg gtcgcggtga ccggagtcct ggtgtgccac cgagtcatcg
    22681 gcccgcgtgg cggacaccgt gcgaacgact gaccagaccg gcgaggtcgg ccgtcgcacc
    22741 ggcggccgac ctcgccgttt cgggccggcg gcgaaacccg cgccgggacc gcccgcttcc
    22801 gggcttgcac ccccgtagcg gggggcggct gccgagcctt tgcccgcgcc ggacagtcac
    22861 cgcccggcac cgccgtcgcg gccgcgtcgc ccaaccgcga tggcacccgt cgtcgaacgg
    22921 cttacgtgtg cgatgccgtt cgggttcgtg cgcgggtact acgccgccaa cctcgtcggc
    22981 ccggcggagt ctgcacgcaa gtgaccacac gccgcccaat gcgcgagcgg cgtgcacggg
    23041 caaggacgac gaagccccag agcaggaggg cgcagtgggt cacgtacatc cctcgcacct
    23101 agtggatctg gcactcggtc acgcggggag cgacgcggac gtcggcgccc tgcggcacgc
    23161 cgagtcgtgc ccgcgctgcc gcgaggaact gctgcggttg acccgcgtgg tgaccactgc
    23221 gcgcagcgtg gaagcatcgg acttgccagt ggctccgccc gagtgcgtgt ggcagcgcat
    23281 ctccctcgaa gtactccagg aaaccgccgg gctgccccga cccgggaaac accccgctca
    23341 ccggtccgcc ggcgggaagg ctagcgttgt gcggcaccgg tggacgaacc gcgcggacgg
    23401 gagccttctc ggacgcgctc tgaccactgc cgtccttctg ctccggcgga ggcggatcaa
    23461 ggccggtcgg gcgactgatc gatagtccga cgcggaggcg gtacgggcca tggactccaa
    23521 cgatgcggag tccggacgtc tcgtcgccgc ccgggcaggc atcgtggtcc ctcgcctctt
    23581 gggagttggg accgaacacg gttgcggctg ccctcgtctc tgagaggcta gttgtgcaga
    23641 ccggcggcgc ggcgggtgtc gtgggtgact cccccaccac cagcgtgccg ctgtctgtgc
    23701 ccaccggggg tgagcgcttg ggctcgccgg accgcggcgc ctgccgtcac ggcgttcgtg
    23761 gcccctgcgg gctgtcgagc gcgtgggccc aggccagcag ttcgggagcg tccagtgacg
    23821 gtaaccacgc gtcggcccgg gtggcaccgt cgccctgcgg ccggggaccg acgcccaaga
    23881 cccgcaggct tgcccggcgg gctgcctcca caccggtcag ggagtcctcc accgcgagcg
    23941 cccggcgtgg ggggacaccg cagagccggg ccgccacggc gtacacgtcg ggatggggct
    24001 tggggcgtac gcggtccccg gcgtcgggga cgacgaggtg ccggaagtgc gcgagcagcc
    24061 cggcccgttc caagctgcct tcgaccacca ctctcgggca gttgctggcc accgcgagcg
    24121 gcaggcggcc ggagagcagc cgtacgagcc gggcagcacc cggcatcgtc accggttctt
    24181 cggtgaccag tgccaggaag tggtcgagaa gcgcggctgt caggtcttcg gccagttcgg
    24241 gtttgtgcac ggcctgggcc atgagtcgac cgcagtcctc gtagtgcagg ccgagggcct
    24301 gctccgcgaa cccgggcggt ggctgaaggc cgtgctcccg gaaggcccgg ctgcgggcct
    24361 cctgccagtg gcgttcgctg tccatgaggg tgccgtcgca gtcgaagacg acggcttcga
    24421 gcgaccagtc gagcaaagcg tggtccaagg tggtcaccgg ggcctcccat gctttcgcat
    24481 gtatgcggca tttccgcctc cacaggaaac ggaaagatag tttccactac gttatttcca
    24541 cccgcacaaa acgggcaata acccttttca gtgactcgac gggcgccaag aacaggtgta
    24601 tggccgtgcg gcgccccgtc tggcgcggcc atcgatagcg acaacgccgc acgcccgctc
    24661 accgattgac acgcgcctga ccgggcaggg gccggagcag cgtattcccg ccgccactcg
    24721 acgcgttcgc gttcgaagga tctgtgtatg cgccgcccga aagagcccgt ttgggctccg
    24781 ggcgtacgct ggcgcactga attcgtgacc cggcatcaga gcccacagcc gctcgtcgat
    24841 ccccgttcgg accgcaggtg ccgagccggc aggccctgtg cggcgtcctc ttggtgaaac
    24901 tgcggtggac gacccagctg aaccaggaac ggacggtgat cgtctcctcg cgcgtgcggg
    24961 ctgccctacg gcacccgaga gcgggccgag cccggtcgac cgcgcacggc cgggcagcaa
    25021 gcaccacctc atgaggaccc accccgtccg catgcccggc tagctgcggg aagcgatact
    25081 ggtaccagcc gcaggacggc gcctgccacg cattcctgtg tctcaagagt tcttacggcc
    25141 ggccgccgcg ggcgcgcggt cgccggaaag gggcgtcacg atgagacgct ggagcccctg
    25201 ctcgggcaca cccgtcatcc tcagcccggt cagcacgaag gtgatcgccc cgcgggcgct
    25261 ccatcccgac gtgtcgttct tgggcgggct gcccgacgaa atccgtctcg tcatgtcgga
    25321 gcccttgagg gacctgccat gcgcggggaa cgaggcgccc gcaagcagtt gcggtgtcct
    25381 cctgccgagt gggggtgtgc tcccccgctt cagccccgac tacgccgacg gtccggggcc
    25441 gtgggggtga agggcgtggg ctcttccgac ggcatggggc ggacaccggg cgataccggc
    25501 accgatccgc tgggcggtcc gtacctgcgc acacgcttcg cccttccctc tcggcctgcc
    25561 acgttcctgc ggcggcaacg gctcgtcgcg cacctgaatc aggctctgcg tacgccgctg
    25621 acggtggtca acggtgcggc cggtgccggc aagacactcc tgacggccga ctgggccgcg
    25681 gggctgcggc tgccggtcgc ctggctgacc gtagaggccg gggatcactt gcccggcgtc
    25741 ttctgggctt acgtcttcga gtccctgcgc gtgcacgggg cccgggcggg cggcaccccc
    25801 ggggcgcccg cggactcgag cggtgtggga cacgggctgc tggcgtcgct cgcctccgag
    25861 ctgaacgccc tcgaccgtcc cgtggtcctc gtactcgacg agtacgaccg gatgaccagc
    25921 cccgaggtcg cagagcagct ggagttcgtc ctgcaccacg ccggaccggg aatgcacctt
    25981 gtcctcgtca cccgcaccga gccgctgctc ccgctgcacc gataccgggc ctccgacgaa
    26041 ctgaccgaga tccgcggctc cgagttgtcc ttcacctcgc aggaagcccg cgcactcctg
    26101 cgactgcacg gactgcaact tcccgagcac gccgcgtccg ccttggtcga ccgcacccga
    26161 ggctgggcgg ccgggctgcg cctgtgcgcc ctggcggccc gggagagcac cgaccccgag
    26221 cagtacttga aggagttcga ggcggaccac agtacggtcg cggacttcct gctggcagag
    26281 gtcctcaaga ggaggacgca ggaggaacag gacctgctgc tgcgggtcag tgtcctggac
    26341 cgtttctgcc cggacctggc cgacgccctc acgctgcgga ccgacgccga aggtctcctc
    26401 gccgggctgc accgggagaa cgcgttcatc gagcggctgg aacactcctg gtaccggctg
    26461 cacccgctgt ttcgggagat actccaagtt catctgcgcg aacgcatgcc cggagtggaa
    26521 gcggagctgc acctgcgagc cgcgcgatgg ctgcgccgtt ccggtttcct ctcggagacg
    26581 ctggcccatg gagccgcggg cggcgacttt gacctggccg ccggcgcact cgtcgacgac
    26641 ctcgcgatcg ggcagctctt caccggcctg cgctcggacg ccctgacgca gctcttcgcc
    26701 ggcatggggt ccgaagcgga gagcccggcg agcaacctcg tgcgggcggc cggcgcactg
    26761 gcacgacgcg acctcgatca cggtctgggg cgactgcgac gggcccaaga gcaactctcc
    26821 gggtccgacg actctcccgg cccggtggca gcccggctga gctgcacgct gctggaggcg
    26881 ctcgccgccc ggctcaccgg atgcccaaca agggccgagc aggccgtcgc gagggccgag
    26941 gaactgcgcc aggacctgcc cgaccatcta ctggacgagc atccggaact gaccgccctg
    27001 ctgctgacac acgtgggctc ggtccgtctg tgggaagggc gcttcgacga cgcacgtgcc
    27061 gcgctcaccc aggtgaccgc cgccccgccg ggacccacca ccgtcctgcc ccgagtggag
    27121 tcgatggggc acctggctct gctcgactac ctgaacggct ggctcggccg ggcggagcgc
    27181 aaagctttgg ccgctgtgtc cgaggcacag cgggcgggtc tgccacggcc ccccggcgcg
    27241 ggcctcggca ggctggtcct ggccgcggtc gccgtggacc gtcaggaact gggcagggcc
    27301 agggcccttc tcgaagagac ggaccggctc ccggcacggg agcacgatcc ggtgccgacg
    27361 gcagggcggg ccctcgccgt ctcacgcctt ctcctcgacg acggtggaac acacacgcac
    27421 gccgctgccg aggctgcgga gccggccgtg tccacggagg cgtcgtcccc gtgggctgag
    27481 ggttacgcgg ccgtcgccca ctctgccgcc tctctcgccg acggacggcc ggaggaggcc
    27541 gtgcggctgc tccacggtgt gtccggtgac caaccggtgt gcgccgtgga agcggcggcg
    27601 atccaggtcg ccgcgggacg accccgtgcg gcggccgaat tactcggcac cgttcggaca
    27661 gagggacgca ccggccccgc ggtgagcgtg ggggcggcgc tggtgcgagc ccgggcagcg
    27721 caggagtcgg gagaggccgc cgtcgcccgc aagctcgtcg cccgtgccct cctcgacgcc
    27781 cggcgcgagc gtctgcgacg ccccttcctc caggcaggag actggatcga gccgctgttg
    27841 gccgcacccc cgctgcacga gctcgccgag ggctggctcc tgcacgacag gccaggagca
    27901 cacggcgaac cggtgcggtc cggatcctcc cccacgcttc tggtgccggt ggagctgagc
    27961 gggcgcgaac gggacgtgct gcggcggctg gccagcatga tgtccacgga ggagatcgcc
    28021 gccgatctgt acctgtcagt caacacggtg aagacccatc tcaagagcgc ctaccggaag
    28081 ctggcggtca accggcgcgg cgacgcggta cgccgcgcgc gcgacctcgg ccttctgtga
    28141 cttcccccgg gaggggtgag gcgagcggcg ccaccgcaga gatgcgatgg gagcaacacg
    28201 tgccgcagca cactgtttcg acccgacgag gtg
//
