LOCUS       NZ_CP089924            10870 bp    DNA     circular CON 08-MAY-2024
DEFINITION  Lysobacter sp. 5GHs7-4 chromosome, complete genome.
ACCESSION   NZ_CP089924
VERSION     NZ_CP089924.1
KEYWORDS    RefSeq.
SOURCE      Lysobacter sp. 5GHs7-4
  ORGANISM  Lysobacter sp. 5GHs7-4
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Lysobacter.
REFERENCE   1  (bases 1 to 4709885)
  AUTHORS   Won,M., Kwon,S.-W. and Woen,H.-Y.
  TITLE     Lysobacter sp. isolated from greenhouse soil
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4709885)
  AUTHORS   Won,M., Kwon,S.-W. and Woen,H.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-DEC-2021) Agricultural Mircrobiology Division,
            National Institute of Agricultural Sciences, 166,
            Nongsaengmyeong-ro, Iseo-myeon, Wanju-gun, Jeollabuk-do 55365, South
            Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: OCT-2021
            Assembly Method                   :: SMRTlink v. 10.1.0.119588
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 128.5x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021284765.1-RS_2024_05_06
            Annotation Date                   :: 05/06/2024 13:59:51
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,243
            CDSs (total)                      :: 4,182
            Genes (coding)                    :: 4,145
            CDSs (with protein)               :: 4,145
            Genes (RNA)                       :: 61
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 37
            CDSs (without protein)            :: 37
            Pseudo Genes (ambiguous residues) :: 0 of 37
            Pseudo Genes (frameshifted)       :: 3 of 37
            Pseudo Genes (incomplete)         :: 34 of 37
            Pseudo Genes (internal stop)      :: 1 of 37
            Pseudo Genes (multiple problems)  :: 1 of 37
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 14:51:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2649715
            Orig. end                         :: 2660585
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089924.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Korean Agricultural Culture
            Collection (KACC).
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10870
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="6"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10870
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10870
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5870](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5870
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            845..1666
                     /locus_tag="LVB77_RS12025"
                     /old_locus_tag="LVB77_12025"
     CDS             845..1666
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011037311.1"
                     /locus_tag="LVB77_RS12025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12025"
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="WP_232906347.1"
                     /transl_table=11
                     /translation="MAGTRPVFYVSDGTGITAETIGHSLLTQFTETRFVTDRIPFVDSV
                     ERAREVGAKIREAAQAHGVRPIVINSCMDGDVGAALAESGALMLDVFAPFIEPLERELE
                     ESRQRRIGQAHGIADFDTYHRRINAMNFALTHDDGQNIDYAEADLILVAVSRAGKTPTC
                     VYLALHYGVRAANYPLTEEDLEHDRLPPRLRPYRNKLFGLTIDPVRLQQIRQERRPNSR
                     YAQFDTCKREVAAAETMFRAERIPTLSTTHTSIEEISSKVLTTLGIHREMF"
     misc_feature    complement(1702..1713)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.48"
                     /tool="antismash"
     gene            1814..2347
                     /locus_tag="LVB77_RS12030"
                     /old_locus_tag="LVB77_12030"
     CDS             1814..2347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003466513.1"
                     /locus_tag="LVB77_RS12030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12030"
                     /product="DUF1249 domain-containing protein"
                     /protein_id="WP_232906348.1"
                     /transl_table=11
                     /translation="MTSLAARSARIPRLTRFGWLMGLYAENHRRLTRLFAPADLAAGTY
                     LSSIGDGLDLQLDVIEQHRYTTELRMTYALLDPLTGEPDPSAWLRLYNDAHQLEATNCY
                     VGRRWQDVIGLYPPPAELIGHRMRMNTFLGKWLEYLAERGHGMATLRPVEIRPPGTPLN
                     AVPGGAAKNLAMNA"
     misc_feature    2210..2212
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    2330..2332
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     tRNA            2393..2468
                     /anticodon=(pos:2652141..2652143,aa:Ala,seq:ggc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LVB77_RS12035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="LVB77_12035"
                     /product="tRNA-Ala"
     gene            2393..2468
                     /locus_tag="LVB77_RS12035"
                     /old_locus_tag="LVB77_12035"
     tRNA            2525..2600
                     /anticodon=(pos:2652274..2652276,aa:Glu,seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LVB77_RS12040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="LVB77_12040"
                     /product="tRNA-Glu"
     gene            2525..2600
                     /locus_tag="LVB77_RS12040"
                     /old_locus_tag="LVB77_12040"
     gene            complement(2725..3051)
                     /locus_tag="LVB77_RS12045"
                     /old_locus_tag="LVB77_12045"
     CDS             complement(2725..3051)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017915216.1"
                     /locus_tag="LVB77_RS12045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12045"
                     /product="hypothetical protein"
                     /protein_id="WP_232906349.1"
                     /transl_table=11
                     /translation="MRPFLRGHEIVDTAIRLDGIALPSNLLRDLAGKSFYFPVNPDDGY
                     IDGSVYLESAHHPVDVTSLNFSAARDGSLTLIVKGVYVFDFEGLDDLERVSFTLAATVS
                     SCAL"
     gene            complement(3177..3491)
                     /locus_tag="LVB77_RS12050"
                     /old_locus_tag="LVB77_12050"
     CDS             complement(3177..3491)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LVB77_RS12050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LVB77_12050"
                     /product="hypothetical protein"
                     /protein_id="WP_232906350.1"
                     /transl_table=11
                     /translation="MDLSQLELHDANLLGVTLDAGARTVEIRLAYYASERASSRTLGSL
                     RFSGVSQFNQVADLERLADHASAGNVIQWRQAERSGAACLHLVGGLIAVTATSVEFVAT
                     "
     gene            3720..4394
                     /locus_tag="LVB77_RS12055"
                     /old_locus_tag="LVB77_12055"
     CDS             3720..4394
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="LVB77_RS12055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12055"
                     /product="DoxX family protein"
                     /protein_id="WP_232906351.1"
                     /transl_table=11
                     /translation="MNRSLAAAVQLPLMSRVDAVGQSLAPLGLRVLLAWEFFEAGREKL
                     LGQNWFAELGDKFPQPFALLGPNLNWTMATWVELLGAIALLLGLGTRYVAAALWVLTVV
                     AIYTVHWPEQWSSLGELWQGYAISNDGYGNYKLPLLYLAMLLPLALNGAGRLSLDRYIA
                     TRRSGVSATAAGKTAWGVVLIAIGLPTSLLLPWVGGALAIAGMGLLLKPRSDAALTGTA
                     TA"
     gene            4487..4942
                     /locus_tag="LVB77_RS12060"
                     /old_locus_tag="LVB77_12060"
     CDS             4487..4942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659349.1"
                     /locus_tag="LVB77_RS12060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12060"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_232906352.1"
                     /transl_table=11
                     /translation="MSSNHTRNTVAGALGIALTGLVLSGSAFAMQPLAQGYMLATGHAA
                     AEGKCGEGKCGAGAGKTAAGKKTAEGKCGEGQCGDARFAATDTDDDGRVSRAEFLKVVP
                     KGEAAFKSKDSDRNGYISEHEAYYSVKAAFKANGKDVPRGLFSGIDE"
     gene            5001..5870
                     /locus_tag="LVB77_RS12065"
                     /old_locus_tag="LVB77_12065"
     CDS             5001..5870
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659081.1"
                     /locus_tag="LVB77_RS12065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12065"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_232906353.1"
                     /sec_met_domain="DUF692 (E-value: 1.6e-116, bitscore:
                     386.2, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKLSPTDARSTSAGLGLRRGLLPELLNLSADAVDFLEVAPDNWI
                     GVGGRFGESLSQLSARFPISAHGLSLSLGGTQPLDTELLRRTREFNDRHQVMLYSEHLS
                     YTNDDGQLYDLMPIPFTDEAIGHVASRIRQVQDALGRRIAVENVSYYAAPYQALAEIDF
                     INAVLAEADTDLLLDVNNLYVNSINHGYDAEAFLARLPGERIASYHIAGHYDEDIDLKV
                     DTHGAPVKSDVWSLLASAYRRFGVRPTLLERDFNFPPMAELLSETDRIRSMQHAYADRA
                     RLLEQAHV"
     gene            5863..6627
                     /locus_tag="LVB77_RS12070"
                     /old_locus_tag="LVB77_12070"
     CDS             5863..6627
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010343982.1"
                     /locus_tag="LVB77_RS12070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12070"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_232906354.1"
                     /transl_table=11
                     /translation="MSERLREQQYTLARHLRDPVAHAPPPGLEPRRLRVYRELFFNNIR
                     GLLGNGFPVIAQTLGEARWTELVHGFYAEHRAQTPLFARIAAEFVAYVEARGGDGLPPW
                     LPELAHYEWVEQALYVSDAQPPAHDPQGDLLNGIPVLSPLALPLAYRWPVAEIGPDRMP
                     DTAPAEPTLLLVHRGIDHQVRFARIAPLVYRLLVGMQSASQTGRQHLAALAAETGDEPA
                     QFIQFGLPLLQQLHAQGVVLGTHIPTEQNHAV"
     gene            6617..7279
                     /locus_tag="LVB77_RS12075"
                     /old_locus_tag="LVB77_12075"
     CDS             6617..7279
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415657.1"
                     /locus_tag="LVB77_RS12075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12075"
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_232906355.1"
                     /transl_table=11
                     /translation="MPSKTASLTGWKLFALLAALVLAMSALILALNADPAEAMRSVIRA
                     TARSSFVLFLAAFVASSLATLVPNGFTRGLVRERRYIGLSFAFSHLVHLGAIFSYGALN
                     PQFWPSRGGLTNLPGTIGYVVIALLTVTSFHAVSKRLSATAWKRLHTAGMWTIALIFGL
                     SFYKRIPTMSTLYAIPFAILCAAVAVRWVGKWAQASKRTQAQRRNVPQHTFPPALES"
     gene            7282..7704
                     /locus_tag="LVB77_RS12080"
                     /old_locus_tag="LVB77_12080"
     CDS             7282..7704
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018973275.1"
                     /locus_tag="LVB77_RS12080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12080"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_232906356.1"
                     /transl_table=11
                     /translation="MSSTLETVVYTAHTHVTGGRVGRGQSSDGAVDVQLSSPGSGRPGT
                     NPEQLFGIGYSACFIGALQFAAAARKIKLPEDASVDAEVALGKTAAGAYQLAVTLHVNL
                     PGLDAGLKRELVDAAHQTCPYSRMTRGNVDVALAIA"
     gene            7733..8260
                     /locus_tag="LVB77_RS12085"
                     /old_locus_tag="LVB77_12085"
     CDS             7733..8260
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460992.1"
                     /locus_tag="LVB77_RS12085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12085"
                     /product="thioredoxin family protein"
                     /protein_id="WP_232906357.1"
                     /transl_table=11
                     /translation="MWKTIIAALCLCLAGAACSPGANATQAQAQTVSAPEFVGIDRWFN
                     SAPLTMAGLKGQVVLVEFWTYSCINCIHVLPHVKQWHQRYRDQGLVVVGVHTPEYDEEH
                     GAAGVQAAMKRYGIEYPVAQDNGYATWNAYGNRFWPALYLIDREGRVVYRHYGEGAYEA
                     TEARIRQLLAAR"
     gene            8357..9097
                     /locus_tag="LVB77_RS12090"
                     /old_locus_tag="LVB77_12090"
     CDS             8357..9097
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017338028.1"
                     /locus_tag="LVB77_RS12090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12090"
                     /product="response regulator transcription factor"
                     /protein_id="WP_232906358.1"
                     /transl_table=11
                     /translation="MEPLDHILVVDDDREIRQMVADYLQKNGLRATAVADGREMRAVLD
                     TNAVDLIVLDLMMPGEDGLTLARNLRAGKHRAIPIVMLTARDDQTDRIVGLEMGADDYV
                     TKPFAARELLARIKAVIRRTRMLPPNLQVTEASQFLAFGRWRLDTTARHLLDPDGTAVA
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAEPFDRSIDLLVSRLRQRLQDDAREQ
                     SYIKTVRSEGYVFSATVTVVGEGA"
     gene            9094..10428
                     /locus_tag="LVB77_RS12095"
                     /old_locus_tag="LVB77_12095"
     CDS             9094..10428
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646327.1"
                     /locus_tag="LVB77_RS12095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LVB77_12095"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_232906359.1"
                     /transl_table=11
                     /translation="MNVARPSRWLPRTIASRLYLILVSGLLIAHGLSFGLLFYERYEAA
                     RSMLAANLEQDVVVAVKLLDRLPAQERADWLPMLRRRTFHYQLGPGQSGGPLASDTARD
                     MSRRIGVALGVRYPIQANAVSAQPERFQVHLRLSDGAPMFIEVQPSVMPLAKWLPYVLL
                     AQLGLLLLCTWIAVRLATRPLERLAAAAETLSPGGEGERLQEGGPTEVAKAVSAFNAMQ
                     DRIADYTKERLQILAAISHDLQTPITRMQLRVESMDESVARDKSLEDLRQMQHLVREGI
                     AYARSAHGASEPALRIDLNAFLDSLVYDYRDTGQDVALSGRVDAPVSTRPHALRRVVAN
                     LIDNALKYTGAAELDVAQDANGEVRISVRDRGPGIPEAELDKVLQPFYRLEASRNRDTG
                     GTGLGLAIAQQLAASIGASLTLRNREGGGLEATVRIRNESRDTVN"
     misc_feature    9589..9591
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10354..10356
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 tcgtccggat tgaccgcgcc ctggaccacc atctcgccca ggccgtagct ggaggtgatg
       61 aagaccacgt cgcggaaacc ggattcggtg tccagggtga acagcacgcc ggaggaaccg
      121 acgttggagc gcaccatcag ctgcacgccg gcggacagga acacgtcctc gtgcttgaag
      181 ccgtggtgta cgcggtaggc gatggcgcgg tcgttgtaga ggctggcgaa gacctccttg
      241 accttgcgca ccacgtcgtc ctcgccggtc acgttcagga aggtttcctg ctggccggca
      301 aaggaggcgt cgggcaggtc ttcggcggta gccgaggagc gcaccgccac cgcgacatcg
      361 ctgccgccgt tgtcggcgca cagctggcgg taggcggcgc ggatgtcctg gtccagggcc
      421 ggctgcagcg gcgcgtcgat gacccagccg cggatctgtc cgccagccgc ggtcagggcc
      481 ggcacgtcct ccacgtccag cgtcgccaga cggtcgaaaa tgcgctggtg caggtcgtta
      541 tgggcgatga agtccttgaa ggcctcggcc gtggtggcgt aaccgcccgg caccgagacc
      601 ccgaggttgg cgaggttgcc gatcatctcg cctagcgagg agttcttgcc gcctacgcgg
      661 gccagatcgt tgaggcgcag cgcgtgcagc cagaggatgt tctcgttcaa ggcacactgt
      721 ctccaagggg ggcgggacgc gtccggtcgc ggccaagcgg atatgatcgc cgctgcgtcg
      781 ggtgcataca agcttgatcc gacgggcttt ttcgtattgg aacgcggttt tggaggggta
      841 agcgatggca ggcacgcggc cggttttcta cgtttcggac ggtaccggca tcaccgccga
      901 gaccataggc cacagcctgc tgacccagtt caccgaaacc cggttcgtga ccgaccgcat
      961 cccgttcgtg gacagcgtcg agcgcgcccg cgaggtcgga gccaagatcc gcgaggccgc
     1021 ccaggcccac ggcgtgcgcc cgatcgtgat caattcctgc atggacggcg acgtgggcgc
     1081 ggccctggcc gagagcgggg cgctgatgct ggacgtgttc gcgccgttca tcgagccgct
     1141 ggagcgcgaa ctggaagaga gccgtcagcg ccgcatcggc caggcccacg gcatcgccga
     1201 tttcgatacc taccaccgcc gcatcaacgc gatgaacttc gccctgaccc acgacgacgg
     1261 ccagaacatc gattacgccg aggccgacct gatcctggta gcggtttcac gcgcgggcaa
     1321 aacccccact tgcgtttacc tggcgttgca ctacggcgta cgcgcggcca actatccgct
     1381 gaccgaggaa gacctggaac acgaccgcct gccgccgcgc ctgcgcccgt accgcaacaa
     1441 gctgttcggc ctgaccatcg acccggtgcg tctgcagcag atccgtcagg agcgccggcc
     1501 caactcgcgc tacgcccagt tcgacacctg caaacgcgag gtcgccgcgg ccgagaccat
     1561 gttccgcgcc gagcgcattc ccacgctgag caccacgcat acctcgatcg aggagatctc
     1621 gagcaaggtg ctgacgacgt tggggatcca ccgcgagatg ttctgagggc cgccttgtgc
     1681 ggccccggcg cacgtcggcg cgaaagcggt ttcgatgtgc ggcctatgat acggcccgaa
     1741 cccttaactt aggcctctgc ggcaggtccg tcaacgctgc cgcaaagcgt ttcgcgcgtg
     1801 tagcatcgcc tgcatgacat cgctcgcagc ccgctccgcg cgcatcccgc gactgacccg
     1861 tttcggttgg ttgatggggc tgtacgcgga gaaccaccgc cgcctcacgc gcctgttcgc
     1921 gcccgccgat ctggccgccg gcacctacct gtcctcgatc ggggacggcc tggacctgca
     1981 gctggacgtg atcgagcagc accgctacac caccgagctg cgcatgacct atgcgctgct
     2041 ggacccgctc accggcgaac ccgatccctc cgcctggctg cgcctgtaca acgacgccca
     2101 ccagctggaa gcgaccaatt gctacgtcgg ccgccgctgg caggacgtga tcggcctgta
     2161 cccgccgccg gcggagctga tcggccaccg catgcgcatg aacacttttt taggaaagtg
     2221 gctcgagtat ctagccgaac gtggtcatgg catggcaaca ttgcgcccgg tcgagattcg
     2281 accgccggga acacccctca acgcagtgcc tggcggggcg gcaaaaaatt tagcgatgaa
     2341 cgcttgacga catcgctgaa cgccagctag aattttcgtc tttccagcac gtggggccat
     2401 agctcagctg ggagagcgct acaatggcat tgtagaggtc gccggttcga tcccggctgg
     2461 ctccaccact cttcgaacac agtgaaaggg tttcgacgag ttagctgcaa gaacaatcag
     2521 ttttgtcccc atcgtctaga ggcctaggac attacccttt cacggtagcg accggggttc
     2581 gaatccccgt ggggacgcca gcaagaacgc aaaagccccg actcgtcggg gcttttgctt
     2641 ttggggcgcc gcagaatcga atccgcgaga acaatggcgc tcggttctga gcgaatctgc
     2701 gccgcgatcg gcgcagtctc gcgattagag cgcgcacgaa ctcacggtcg cggccagcgt
     2761 gaacgacacg cgctcaagat cgtccaggcc ttcgaaatcg aacacgtaaa cccctttcac
     2821 gatgagggtg aggctgccgt cgcgcgctgc gctgaagttc agcgaggtga catcgaccgg
     2881 atgatgcgcg ctttccagat agaccgaccc gtcgatgtag ccgtcatcgg gattgaccgg
     2941 aaaatagaac gatttcccgg ccagatcgcg cagcaggttc gagggcaggg cgatgccgtc
     3001 caggcggatc gcggtgtcga cgatctcgtg cccgcgcagg aacgggcgca tcaggatcgt
     3061 gatcgatacg tcgcccggcg ttccggacag gatcgcgtga cgggacttta gatccttggg
     3121 cgagaaagtg gccatggccg tccgatatct gtgctgcgcc ggattcgata agcggatcag
     3181 gttgcgacga actccaccga cgtggcggtc accgcgatca gcccaccgac gagatggagg
     3241 caagccgcgc cggagcgctc cgcctgcctc cattggatca cgttgccggc cgacgcgtga
     3301 tccgccagcc gttccaggtc ggcgacttga ttgaactggc tgacgcctga aaagcgcagg
     3361 ctgcccagag ttcgtgagga tgcccgttcg ctcgcgtagt aggccagccg gatctcgacc
     3421 gtgcgcgcgc cagcgtcgag cgttacgccc aacaaattgg cgtcgtgcag ttcgagttgc
     3481 gaaagatcca tcggcgtcgc tctcctggat gcctggccgc gcctgcgatt ctgcacgaat
     3541 gcgcggtact ggatcgatgt cgccggcacg ccttcgccgc agcggtggcc cctggtttgt
     3601 atcgaactgt atccacggcc gggaacgcga cggttgcata caaaaccgcc cgtcgccgga
     3661 cacctcccgg ataccgcccg cgttcgaaat agcgccaccg aatcgccgag gccttcccca
     3721 tgaaccgctc gcttgccgcc gctgtgcaac tgcccctgat gtcccgcgtc gacgccgtcg
     3781 gccaatcgct ggcgccgttg ggcctgcgcg tcctgctggc ctgggagttc ttcgaggccg
     3841 gccgcgaaaa gctgctgggc cagaactggt tcgccgagtt gggcgacaag tttccgcagc
     3901 cgttcgcact gctcggcccc aacctcaact ggacgatggc gacctgggtg gagctgctcg
     3961 gcgcgatcgc gctgctgctg ggcctgggca cgcgctacgt cgccgccgcg ctgtgggtgc
     4021 tgacggtggt ggcgatctac accgtgcatt ggcccgaaca gtggtcgagc ctgggcgagc
     4081 tttggcaggg ctacgcgatc agcaacgacg gctacggcaa ctacaagctg ccattgctgt
     4141 acctggcgat gctgctgccg ctggcgctca acggcgcagg gcgcctcagc ctggaccgct
     4201 acatcgcaac ccgtcgctcc ggcgtaagcg ccactgcggc cggcaagacc gcctggggcg
     4261 tggtgctgat cgcgatcggc ctgccgacct cgctgctgct gccctgggtc ggcggcgcgc
     4321 tggccatcgc cggcatggga ttgctgctca agccgcgctc cgatgccgcc ttgactggca
     4381 cggctaccgc ctaagcgatc gcccgattcc cctccctttc caaattcgcg ccgcatccgc
     4441 gacgcatccc ccgcggcgtg gccgcaccga acctggagta accgcaatgt cttccaacca
     4501 cacccgcaac accgtcgccg gcgcgctcgg catcgccctg accggcctgg ttctgagcgg
     4561 ctcggccttc gccatgcagc cgctggcgca gggctacatg ctcgccaccg gccatgccgc
     4621 cgccgagggc aagtgcggcg aaggcaagtg cggcgccggt gccggcaaga ccgctgccgg
     4681 caagaagacc gccgaaggca agtgcggcga aggccaatgc ggcgatgcgc gcttcgccgc
     4741 gaccgacacc gacgacgacg gccgcgtttc gcgtgccgag ttcctgaagg tggtgcccaa
     4801 gggcgaggcc gcgttcaaga gcaaggacag cgaccgcaac ggctacatct ccgagcacga
     4861 ggcgtactac agcgtgaagg ccgccttcaa ggccaacggc aaggacgttc cgcgcggcct
     4921 gttctccggc atcgacgaat aaaccgccgc cctgacgcgt ccccacggat cccgtgggga
     4981 cgctactcga gagttccgtc atgtccaagc tcagccccac cgacgctcgc tccacttccg
     5041 ctggcctggg cctgcgccgc ggcctgctgc cggagctgct gaatctgtct gccgacgccg
     5101 tggacttcct ggaagtcgcg cccgacaact ggatcggcgt gggcggccgc ttcggcgagt
     5161 cgctgtcgca gctgtcggcg cgttttccga tcagcgccca cggcttgtcg ctgtcgctgg
     5221 gcggtacgca accgctggac accgagctgc tacgccgcac ccgcgagttc aacgaccgcc
     5281 atcaggtcat gctgtacagc gaacacctga gctacaccaa cgacgacggg cagctgtacg
     5341 acctcatgcc catcccgttc accgacgagg ccatcggcca cgtcgcctcg cgcatccgcc
     5401 aggtgcagga cgcgctgggc cggcgcatcg cggtggagaa cgtgtcctat tacgccgcgc
     5461 cgtatcaggc gctggccgag atcgatttca tcaatgccgt cctggccgag gccgataccg
     5521 acctgctgtt ggacgtcaac aacctgtacg tgaactcgat caaccacggc tacgacgccg
     5581 aggccttcct ggcgcgtctg ccgggcgagc gtatcgcctc gtaccacatc gccggccact
     5641 acgacgaaga catcgacctg aaggtggaca cgcacggcgc gccggtgaaa tccgacgtgt
     5701 ggtcgttgct ggccagcgcc tatcgccgct tcggggtgcg tccgacgttg ctggagcgcg
     5761 acttcaattt tccgccgatg gccgaactgc tgtcggaaac cgatcgcatc cgctcgatgc
     5821 agcacgccta cgccgatcgc gcacgcttgc tggagcaggc ccatgtctga gcgcctgcgc
     5881 gaacagcagt acaccctggc gcggcacctg cgcgatcccg tcgcccacgc gccgccgccg
     5941 ggcctggaac cgcgccgcct gcgcgtgtac cgcgagctgt tcttcaacaa catccgcggt
     6001 ctgctgggca acggcttccc ggtgatcgcc cagaccctgg gcgaggcgcg ctggaccgag
     6061 ctggtgcacg gcttctacgc cgaacaccgg gcgcagacgc cgttgttcgc gcgtatcgcg
     6121 gcggagttcg tcgcctatgt ggaagcccgt ggcggcgacg gtctgccgcc gtggctgccc
     6181 gaactggcgc attacgaatg ggtggagcag gccttgtacg tcagcgatgc ccagccgccc
     6241 gcgcacgatc cgcaaggcga cctgctgaac ggcatacccg tgctgtcgcc actggcgctg
     6301 ccgctggcct atcgctggcc ggtcgcggag atcggtccgg atcgcatgcc cgacaccgcg
     6361 ccggccgagc cgacgctgct gctggtgcat cgcggcatcg atcaccaggt gcgcttcgcc
     6421 cgcatcgcgc cgctggtgta ccgactgctg gtgggcatgc agagcgcgtc gcagacggga
     6481 cggcaacatc tggccgcgct cgccgccgaa accggggacg agcctgcgca gttcatccag
     6541 ttcggcttgc cgctactgca acaactgcat gcacagggcg tggtcctggg cacccacata
     6601 ccaacggagc aaaaccatgc cgtctaagac cgcaagcctc accggatgga agctgttcgc
     6661 gctgctggcg gccctggtgc tggcgatgtc ggcgctgatc ctggcgctga acgccgaccc
     6721 ggccgaggcg atgcgctcgg tgatccgcgc caccgcgcgc agttcgttcg tactgttcct
     6781 ggcggcgttc gtggcctcgt cgctggcgac cctggtgccg aacggattca cccgcggcct
     6841 ggtgcgcgag cgccgctaca taggcctgtc gttcgcgttc tcgcacctgg tgcacctggg
     6901 cgcgatcttc agttacggcg cgctcaaccc acaattctgg cccagccgcg gcggactcac
     6961 caatctgccg ggcacgatcg gctacgtggt catcgcgctg ctgacggtca cctccttcca
     7021 tgcggtctcc aagcgtctgt cggcgacggc atggaagcga ctgcacacgg ccggcatgtg
     7081 gacgatcgcc ttgatcttcg gcctctcgtt ctacaagcgc attcccacca tgagcacgct
     7141 gtacgcgatt ccgttcgcca tcctgtgcgc cgccgtcgcg gtgcgctggg tcggcaagtg
     7201 ggcgcaggcc agcaaacgca cgcaagcgca acgccgcaac gtcccgcaac acacctttcc
     7261 cccagcattg gagtcatgat catgagcagc accctcgaaa ccgtcgttta caccgcccac
     7321 acccatgtca ccggcggccg cgtcggccgc ggccagtcca gcgatggcgc cgtcgatgtc
     7381 cagctgagtt cgcccggttc cggccgtccg ggcaccaatc cggagcaact gttcggcatc
     7441 ggctactcgg cctgcttcat cggcgcgctg cagttcgccg cggcggcgcg caaaatcaag
     7501 ttgcccgaag acgcctccgt cgacgccgag gtggccctgg gcaagaccgc cgccggcgcc
     7561 tatcagttgg cggtgactct gcacgtgaac ctgccgggct tggacgcggg tctcaagcgt
     7621 gaactggtcg atgccgcgca ccagacctgc ccgtactcgc gcatgacgcg cggcaacgtc
     7681 gacgtggcgc tggcgatcgc ctgacccgcg ccgccgccca ggagcgatca ccatgtggaa
     7741 aacgatcatc gccgcgctgt gcctgtgcct ggccggcgcg gcctgttcgc ccggcgcgaa
     7801 cgccacccag gcgcaagcgc aaacggtgtc ggcaccggag ttcgtcggca tcgaccgttg
     7861 gttcaacagc gcgccgctga ccatggccgg tttgaagggg caggtggtgc tggtggagtt
     7921 ctggacctat tcctgcatca actgcatcca tgtgctgccg cacgtgaagc agtggcatca
     7981 acgctatcgc gaccagggtc tggtggtggt gggcgtgcac acgccggagt acgacgagga
     8041 gcatggcgcg gccggcgtgc aggcggcgat gaaacgctac ggtatcgagt acccggtggc
     8101 gcaggacaac ggctacgcga cctggaacgc ctacggcaac cgcttctggc cggccttgta
     8161 cctgatcgac cgcgagggca gggtggtcta ccggcactac ggcgagggcg cgtacgaggc
     8221 caccgaggcg cgtatccggc aactgctggc ggcgcgctga cggcggtgcg ctgcccgccg
     8281 cgggctgcct aagtcctggc gtccaacggc ataatcgcgg gtggcgcccg ccaccagccc
     8341 tctctcggga atcgtaatgg aacccctcga tcacatcctg gtcgtcgacg acgatcgcga
     8401 gatccggcag atggtggcgg actacctgca aaagaacggc ctgcgcgcca ccgccgtggc
     8461 cgacggccgc gaaatgcgcg cggtgctgga tacgaacgcc gtggatctga tcgtgctgga
     8521 cctgatgatg ccgggcgaag acggcctgac tctggcgcgc aacctgcgcg cgggcaagca
     8581 ccgcgccatc ccgatcgtga tgctgaccgc ccgcgacgac cagaccgacc gcatcgtcgg
     8641 cctggaaatg ggcgccgacg actacgtcac caaacccttc gccgcgcgcg agctgctggc
     8701 gcggatcaag gcggtgatcc gacgcacgcg catgctgccg ccgaatctgc aggtgaccga
     8761 agccagtcag ttccttgcgt tcggacgctg gcgcctggac accacggcac gccacctgct
     8821 cgaccccgac ggcacggcgg tggccttgag cggcgccgag ttccggctgt tgcgcgtgtt
     8881 cctcgaccac gccaaccgcg tgctcagccg cgatcagttg ttgagcctga cccagggccg
     8941 cgatgccgag ccgttcgacc gctccatcga cctgctggtc agccgtctgc gccagcgcct
     9001 gcaggacgat gcccgcgagc agagctacat caagaccgtg cgcagcgaag gctacgtgtt
     9061 cagcgccacg gtgacggtgg tgggcgaggg cgcatgaacg tggcgcgccc ctcgcgctgg
     9121 ctgccgcgca ccatcgcctc gcgcctgtat ttgatcctgg tcagcggcct gctgatcgcg
     9181 cacgggctgt cgttcggcct gctgttttac gaacgctacg aggcagccag gtcgatgctg
     9241 gccgccaacc tcgaacagga cgtggtggtc gcggtcaaac tattggatcg cctgccggcg
     9301 caggagcgcg cggattggct gcctatgctg cgccgtcgca ccttccacta tcagcttggc
     9361 cctgggcaga gcggtggccc cttggccagc gataccgcgc gggacatgag ccgtcgcatc
     9421 ggcgtcgcgc tgggcgtgcg ttatcccatc caggccaacg ccgtatcggc gcagcccgag
     9481 cgcttccagg tccacttgcg actcagcgac ggcgcgccca tgttcatcga ggtacagccc
     9541 tcggtgatgc cgctggcgaa gtggctgcct tacgtactgc tcgcgcagtt aggcctgctg
     9601 ctgctgtgca cctggatcgc ggttcggctg gcgacgcgtc cgctggaacg gctggccgcc
     9661 gccgccgaaa ccctgagccc cggcggcgaa ggcgagcgcc tgcaagaagg cggtcccacc
     9721 gaagtggcca aggcggtgtc ggcattcaac gccatgcagg atcgcatcgc cgattacacc
     9781 aaggaacgat tgcagatcct cgcggcgatt tcgcacgacc tgcaaacgcc gatcacgcgc
     9841 atgcagctgc gcgtcgaatc catggacgaa tccgtcgcgc gcgacaaaag cctcgaagac
     9901 ttgcggcaga tgcagcacct ggtgcgcgaa ggcatcgcct atgcgcgcag cgcccacggc
     9961 gcctcggaac cggcattgcg catcgacctc aacgccttcc tcgacagcct ggtctacgac
    10021 taccgcgaca ccggccagga cgtcgccctg agcgggcgcg tggacgcgcc ggtaagcaca
    10081 cgaccgcatg cgctgcgacg cgtcgtggcg aacctgatcg acaacgcgct caaatacacc
    10141 ggcgccgccg aactcgatgt cgcgcaggac gcgaacggcg aagtgcgcat cagcgtgcgc
    10201 gaccgcggcc cgggcatccc ggaagccgaa ctggacaaag tgttgcaacc gttctatcgc
    10261 ctggaggcat cgcgcaatcg cgatacgggc ggcaccggcc tggggttggc catcgcgcag
    10321 cagttggccg cttcgatcgg tgccagcctg acgttacgca atcgcgaggg cggcggtctc
    10381 gaagccaccg tgcgcattcg caatgagagc cgcgacacgg tgaactgaga tgcgctcgcc
    10441 ggaggcgagg ctcaatgcac cgcttcgtta ccgccgctgg gcgcgtccag cgaggtgcgc
    10501 tggccgtcgg ccagttcctt ctcgaactcg gcctcgaact gctcgaagct caggccgcgg
    10561 tcggcggcct cctgggcggc ggcggcgctg agcgcgggcg agaacttcag ctgcacgctt
    10621 tcgccctcgc gctcgtgcag ggcggcggcg cgcttgagca tgatcagcac cttggcggcg
    10681 ctgtcggagc cgccgacgat gcggccgccc aggcccagcg tccattcgcc gtcgcggcgc
    10741 acgatgccgc ccaggagctg gccgttgcgg tcgcgcattt ccgcgtgcgg ctcgatcgcg
    10801 gccggggccg gcgctcgcac ggccttggcg gccttgcgct tcttggcgtc gcggcgggct
    10861 ttggaatgga
//
