LOCUS       NZ_CP089148            21699 bp    DNA     circular CON 12-FEB-2024
DEFINITION  Bacillus subtilis strain NIB353 chromosome, complete genome.
ACCESSION   NZ_CP089148
VERSION     NZ_CP089148.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4247447)
  AUTHORS   Yoon,J.-A. and Kim,M.-D.
  TITLE     Complete genome sequence of Bacillus subtilis NIB353 isolated from
            nuruk
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4247447)
  AUTHORS   Yoon,J.-A. and Kim,M.-D.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-DEC-2021) Division of Food Biotechnology and
            Biosystems Engineering, Kangwon National University,
            Kangwondaehackgil-1, Chuncheon, Gangwon-do 24341, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: NOV-2021
            Assembly Method                   :: Unicycler v. v0.4.8
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 147.33x
            Sequencing Technology :: Oxford Nanopore MinION; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/12/2024 03:57:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,839
            CDSs (total)                      :: 4,716
            Genes (coding)                    :: 4,578
            CDSs (with protein)               :: 4,578
            Genes (RNA)                       :: 123
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 88
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 138
            CDSs (without protein)            :: 138
            Pseudo Genes (ambiguous residues) :: 0 of 138
            Pseudo Genes (frameshifted)       :: 83 of 138
            Pseudo Genes (incomplete)         :: 63 of 138
            Pseudo Genes (internal stop)      :: 20 of 138
            Pseudo Genes (multiple problems)  :: 24 of 138
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:34:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4144820
            Orig. end                         :: 4166519
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP089148.1.
            Bacteria and source DNA available from Kangwon National University.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21699
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="epipeptide"
                     /region_number="11"
                     /rules="(TIGR04078 and yydH)"
                     /tool="antismash"
     cand_cluster    1..21699
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04078 and yydH)"
                     /kind="single"
                     /product="epipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21699
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11699](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04078 and yydH)"
                     /neighbourhood="10000"
                     /product="epipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11699)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04078 and yydH)"
                     /neighbourhood="10000"
                     /product="epipeptide"
                     /protocluster_number="1"
     misc_feature    complement(4..18)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 17.46"
                     /tool="antismash"
     gene            193..1539
                     /gene="gntP"
                     /locus_tag="LRO88_RS22415"
     CDS             193..1539
                     /codon_start=1
                     /gene="gntP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391887.1"
                     /locus_tag="LRO88_RS22415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gluconate permease GntP"
                     /protein_id="WP_003243139.1"
                     /transl_table=11
                     /translation="MPLIIVALGILALLFLIMGLKLNTFISLLVVSFGVALALGMPFDK
                     VVSSIEAGIGGTLGHIALIFGLGAMLGKLIADSGGAQRIAMTLVNKFGEKNIQWAVVIA
                     SFIIGIALFFEVGLVLLIPIVFAISRELKISILFLGIPMVAALSVTHGFLPPHPGPTAI
                     AGEYGANIGEVLLYGFIVAVPTVLIAGPLFTKFAKKIVPASFAKNGNIASLGTQKTFNL
                     EETPGFGISVFTAMLPIIIMSVATIIDLLQETIGFADNGVLAFIRLIGNASTAMIISLL
                     VAVYTMGIKRNIPVKTVMDSCSTAISQIGMMLLIIGGGGAFKQVLINGGVGDYVADLFK
                     GTALSPIILAWLIAAILRISLGSATVAALSTTGLVIPLLGHSDVNLALVVLATGAGSVI
                     ASHVNDAGFWMFKEYFGLSMKETFATWTLLETIISVAGLGFILLLSLVV"
     gene            1562..2968
                     /gene="gnd"
                     /locus_tag="LRO88_RS22420"
     CDS             1562..2968
                     /EC_number="1.1.1.44"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="gnd"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391888.1"
                     /locus_tag="LRO88_RS22420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="decarboxylating NADP(+)-dependent
                     phosphogluconate dehydrogenase"
                     /protein_id="WP_029318564.1"
                     /transl_table=11
                     /translation="MFNTIGVIGLGVMGSNIALNMANKGENVAVYNYTRDLTDQLIQKL
                     DGQSLSPYYELEDFVQSLEKPRKIFLMVTAGKPVDSVIQSLKPLLEEGDVIMDGGNSHY
                     EDTERRYDELKEKGIGYLGVGISGGEVGALTGPSIMPGGDRDVYEKAAPILTKIAAQVG
                     DDPCCVYIGPKGAGHFTKMVHNGIEYADMQLIAEAYTFLRETLRLPLDEIASIFETWNQ
                     GELKSYLIEITAEILRKKDEKTGQPLIDVILDKTGQKGTGKWTSMQAIDNGIPSTIITE
                     SLFARYLSSLKEERMAAQDVLAGPEAEEKHLDKDTWIEYVRQALYMGKVCAYAQGFAQY
                     KMSSELYGWNLPLKDIALIFRGGCIIRADFLNVISEAFSEQPNLANLLIAPYFTDKLHA
                     YQTGLRKVVCEGISTGISFPCLTTALSYYDGYRTGRSNANLLQAQRDYFGAHTYERTDM
                     DGVFHTNWSE"
     misc_feature    complement(3238..3252)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.04"
                     /tool="antismash"
     gene            3434..3997
                     /gene="ahpC"
                     /locus_tag="LRO88_RS22425"
     CDS             3434..3997
                     /EC_number="1.11.1.26"
                     /GO_function="GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ahpC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391889.1"
                     /locus_tag="LRO88_RS22425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="WP_003243686.1"
                     /transl_table=11
                     /translation="MSLIGKEVLPFEAKAFKNGEFIDVTNEDLKGQWSVFCFYPADFSF
                     VCPTELEDLQEQYAALKELGVEVYSVSTDTHFVHKGWHDSSEKISKITYAMIGDPSQTI
                     SRNFDVLDEETGLADRGTFIIDPDGVIQTVEINAGGIGRDASNLVNKVKAAQYVRQNPG
                     EVCPAKWEEGGETLTPSLDLVGKI"
     gene            4011..5540
                     /gene="ahpF"
                     /locus_tag="LRO88_RS22430"
     CDS             4011..5540
                     /GO_function="GO:0016668 - oxidoreductase activity, acting
                     on a sulfur group of donors, NAD(P) as acceptor [Evidence
                     IEA]"
                     /GO_process="GO:0006805 - xenobiotic metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0009398 - FMN biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ahpF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391890.1"
                     /locus_tag="LRO88_RS22430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="WP_003226996.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.8e-45, bitscore:
                     151.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLDANIKAQLNQYMQLIENDIVLKVSAGEDDTSKDMLALVDELA
                     SMSSKISVEKAELNRTPSFSVNRVGEDTGVTFAGIPLGHEFTSLVLALLQVSGRPPKVD
                     QKVIDQVKKISGEYHFESYISLTCHNCPDVVQALNMMSVLNPNITHTMIDGAAYKAEVE
                     SKNIMAVPTVYLNGESFGSGRMTLEEILAKMGSGADASEFADKEPFDVLVVGGGPAGAS
                     AAIYTARKGIRTGVVAERFGGQVLDTMSIENFISVKATEGPKLAASLEEHVKEYDIDVM
                     NLQRAKRLEKKDLFELELENGAVLKSKTVILSTGARWRNVNVPGEQEFKNKGVAYCPHC
                     DGPLFEGKDVAVIGGGNSGIEAAIDLAGIVNHVTVLEFAPELKADEVLQKRLYSLPNVT
                     VVKNAQTKEITGDQSVNGITYVDRETGEEKHVELQGVFVQIGLVPNTEWLEGTVERNRM
                     GEIIVDKHGATSVPGLFAAGDCTDSAYNQIIISMGSGATAALGAFDYLIRN"
     gene            complement(5650..7089)
                     /gene="bglA"
                     /locus_tag="LRO88_RS22435"
     CDS             complement(5650..7089)
                     /EC_number="3.2.1.86"
                     /codon_start=1
                     /gene="bglA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391891.1"
                     /locus_tag="LRO88_RS22435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="WP_014481445.1"
                     /transl_table=11
                     /translation="MGNMPKDFLWGGALAAHQFEGGWNQGGKGPSVVDVMTAGAHGVPR
                     KITDTIEENEFYPNHEAIDFYHRYKEDIALFAEMGLKCLRTSIGWSRIFPKGDEAEPNE
                     AGLQFYDDVFDELLKHGIEPVITLSHFEMPLHLAREYGGFRNRKVVDFFVNFADACFTR
                     YKEKVKYWMTFNEINNQMDVNNPLFLWTNSGVVVGENENAKEVMYQTAHHELVASALAV
                     AKGKDINPEFQIGAMVSHVPIYPFSSNPKDVMLAEEEMRQRYFFPDVQVRGYYPSYALK
                     EFEREGYNITFEDGDDEILRNGTVDYLGFSYYMSTTVKSDVKNDNTDDIVNGGLPNGVE
                     NPYITSSDWGWAIDPTGLRYTLNRFYDRYQIPLFIVENGFGAVDTLEEDGKVHDPERIQ
                     YLKSHIEALKKAVTYDGVDLIGYTPWGIIDIVSFTTGEMKKRYGMIYVDRDNEGNGSMK
                     RYKKDSFEWYKNVIQTNGEEL"
     gene            complement(7103..7520)
                     /locus_tag="LRO88_RS22440"
                     /pseudo=""
     CDS             complement(7103..7520)
                     /GO_process="GO:0009401 - phosphoenolpyruvate-dependent
                     sugar phosphotransferase system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017813308.1"
                     /locus_tag="LRO88_RS22440"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="PTS glucose transporter subunit IIA"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSGKVRDYTRLAKDILEAVGGEENVIGASRCATRLRLVLKRSTPK
                     AKDIVKSMLPSRRHYGCHGYAYKACDWPAFSVQRRIACAHRAGYGDIRRQAFFLEGKRR
                     RYRQKRRSAC"
     gene            7678..8388
                     /gene="yydK"
                     /locus_tag="LRO88_RS22445"
     CDS             7678..8388
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="yydK"
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391893.1"
                     /locus_tag="LRO88_RS22445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_017697259.1"
                     /transl_table=11
                     /translation="MLKYQQIATEIETYIEEHQLQQGDKLPVLETLMAQFEVSKSTITK
                     SLELLEQKGAIFQVRGSGIFVRKHKRKGYISLLSNQGFKKDLEDFNVTSKVIELDVRKP
                     TPEAAENLNIGMDEDIYYVKRVRYINGQTLCYEESYYTKSIVTYLNNEIVSHSTFHYIR
                     EGLGLKIGFSDLFLHVGQLNEEEAEYLGLEAGLPKLYIESIFHLTNGQPFDYSKISYNY
                     EQSQFVVQANSFLL"
     gene            complement(8479..9201)
                     /gene="liaM"
                     /locus_tag="LRO88_RS22450"
     CDS             complement(8479..9201)
                     /codon_start=1
                     /gene="liaM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391894.1"
                     /locus_tag="LRO88_RS22450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptide ABC transporter permease"
                     /protein_id="WP_032725004.1"
                     /transl_table=11
                     /translation="MKLEFKKSISNKVIIILGAMFVFLFLLGYFLLVGIDKVSNVTPEM
                     FFFSSYTVATQFGLMLFSFVIAFFINREYSNKNILFYKLIGENIYTFFYKKIAVLFLEC
                     FAFITLGLLIISLMYHDFSHFALLLFLFSAVILQYILIIGTISVLCPNILISIGVSIVY
                     WMTSVILVAISNKTFGFIAPFEAGNTMYPRIERVLQSDNMTLGSNDVLFIILYLVSIII
                     INAIILRFSKTRWIKMGI"
     gene            complement(9222..9851)
                     /gene="liaL"
                     /locus_tag="LRO88_RS22455"
     CDS             complement(9222..9851)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="liaL"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391895.1"
                     /locus_tag="LRO88_RS22455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_014481448.1"
                     /transl_table=11
                     /translation="MNIANYTLKVKGKTLLQDTDLHFSSGKINHVVGKNGVGKSQLAKD
                     FLLNNSKRIGRDIRQNVSLISSSSNIPNDVSKDFLLHFLSKKFDAEMIDKIAHLLNLDN
                     IDGKVLIKNLSDGQKQKLKLLSFLLEDKNIIVLDEITNSLDKKTVIEIHGFLNKYIQEN
                     PEKIIINITHDLSDLKAIEGDYYIFNHQEIQQYHSVDKLIEVYINE"
     gene            complement(10001..10759)
                     /gene="liaK"
                     /gene_synonym="yydH"
                     /locus_tag="LRO88_RS22460"
     CDS             complement(10001..10759)
                     /codon_start=1
                     /gene="liaK"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     epipeptide: yydH"
                     /gene_kind="biosynthetic"
                     /gene_synonym="yydH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391896.2"
                     /locus_tag="LRO88_RS22460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc metalloprotease LiaK"
                     /protein_id="WP_017697257.1"
                     /sec_met_domain="yydH (E-value: 3.6e-153, bitscore: 508.1,
                     seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILKYEDEKYEVLVQNNVFIKDKKSGEYYKNSLNSLSDEQLLRF
                     KMYKEKVSPKFFYLFLSFTALMFILNYIHLIKLQNGLSSVFYGWKMWIIIVIYFIMNIV
                     LHELGHIYSLKFFGKNFDKVGFKLNFYVFPAFYVQLNETYMLSRNEKIIVHLFGLFINY
                     FLINTLELINQFTFSSEALTMAFMLFSSTLLWNLIPILNSDGYKILLAFLSLDEYSRFK
                     TNHWLVLTIQIIGIGLAVNSVVHWILYIVN"
     gene            complement(10740..11699)
                     /gene="liaE"
                     /locus_tag="LRO88_RS22465"
     CDS             complement(10740..11699)
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="liaE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     epipeptide: TIGR04078"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391897.1"
                     /locus_tag="LRO88_RS22465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YydG family radical SAM peptide epimerase"
                     /protein_id="WP_159377167.1"
                     /sec_met_domain="TIGR04078 (E-value: 1.2e-172, bitscore:
                     571.4, seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 6.8e-08, bitscore: 30.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8.5e-06, bitscore: 23.4,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 9.5e-11, bitscore: 40.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYNKTVSINLDSRCNASCDHCCFSSSPTSTTRMEKEYIRELVTEF
                     AKNKTIQVISFTGGEVFLDYKFLKELMEIIKPYEKQITLISNGFWGLSKKKVQEYFHDM
                     NSLNVIALTISYDEYHAPFVKSSSIKNILEHSRKYPDIDISLNMAVTKDKMSNHILEEL
                     GDSILGVKITKFPMVSVGAAKTRIKQENIHKFYSLEDEDSLHCPGYDIVYHHDGEIYPC
                     CSPAIFETKITLREEYNQSFERTVEKLNSNLLLFILRKEGFKWFLNILKENNKIEEFDI
                     PYEFSSICGVCGSLFNSAEKINYFYPYMEKYYNENFKV"
     misc_feature    complement(11683..11701)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 25.45"
                     /tool="antismash"
     gene            complement(11757..11906)
                     /gene="liaD"
                     /locus_tag="LRO88_RS22470"
     CDS             complement(11757..11906)
                     /codon_start=1
                     /gene="liaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614717.1"
                     /locus_tag="LRO88_RS22470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="epipeptide YydF family RiPP"
                     /protein_id="WP_014478520.1"
                     /transl_table=11
                     /translation="MKKENTNNETVKNLEFKGLLDESQKLAKVNDLWYFVKSKENRWIL
                     GSGH"
     gene            12397..14322
                     /gene="fbp"
                     /locus_tag="LRO88_RS22475"
     CDS             12397..14322
                     /codon_start=1
                     /gene="fbp"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391899.2"
                     /locus_tag="LRO88_RS22475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="WP_159377168.1"
                     /transl_table=11
                     /translation="MESKYLDLLAQKYDCEEKVVTEIINLKAILNLPKGTEHFVSDLHG
                     EYQAFQHVLRNGSGRVKEKIRDIFSGVIYDREIDELAALVYYPEDKLKLIKHDFDAKPA
                     LNEWYKETIHRMIKLVSYCSSKYTRSKLRKALPAQFAYITEELLYKTEQAGNKEQYYSE
                     IIDQIIELGQADKLITGLAYSVQRLVVDHLHVVGDIYDRGPQPDRIMEELINYHSVDIQ
                     WGNHDVLWIGAYSGSKVCLANIIRICARYDNLDIIEDVYGINLRPLLNLAEKYYDDNPA
                     FRPKADDNRPEDEIKQITKIHQAIAMIQFKLESPIIKRRPNFNMEERLLLEKIDYDKNE
                     ITLNGKTYQLENTCFATINPEQPDQLLEEEAEVIDKLLFSVQHSEKLGRHMNFMMKKGS
                     LYLKYNGNLLIHGCIPVDENGNMETMMIEDKPYAGRELLDVFERFLREAFAHPEETDDL
                     ATDMAWYLWTGEYSSLFGKRAMTTFERYFIKEKETHKEKKNPYYYLREDEATCRNILAE
                     FGLNPDHGHIINGHTPVKEIEGEDPIKANGKMIVIDGGFSRAYQSTTGIAGYTLLYNSY
                     GMQLVAHKHFNSKAEVLSTGTDVLTVKRLVDKELERKKVKETNVGEELLQEVAILESLR
                     EYRYMK"
     gene            complement(15573..16490)
                     /locus_tag="LRO88_RS22480"
     CDS             complement(15573..16490)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LRO88_RS22480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159377169.1"
                     /transl_table=11
                     /translation="MAICMLRYLFHIKLALPEDIGFFVQYKGNKSLVRVKTINGANISS
                     YTNKDLSWLFQEDGNQNNNLSVLKISTNDPLEQIPLRYIHYYNNKDHFSAGVVEPTNFS
                     IFEVSFNIPNKDFLDKEDNIRLLDNSAFDIINDFTNKYRLVSQENDIYLPRSNESPVIE
                     IWYSDLVEQKGELISANLKPYKETVNFNGLKKLNKPILTKEKIEKLNNLLKTGSRIPLY
                     QQLLLEAKEQGHINNNYELSVVKIGTSFEVFLKELLVNACQNIGIQKLPVGRGRDLEKL
                     PTKNYKEAIQEGNIKEDLLKNILK"
     gene            complement(16617..18092)
                     /locus_tag="LRO88_RS22485"
     CDS             complement(16617..18092)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LRO88_RS22485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116315657.1"
                     /transl_table=11
                     /translation="MGYKLELLKSIHFGERVAEDDSNLADYFVETNIWKQLINDRIDVV
                     YGAKGSGKSALYRHLLHKESFFTERDILLIPAENIRGATVFKQVLGNQELNEESFRHLW
                     FMYILTLIGDKIKSYKDDYKKVRLFISKLEDEGLLNGSGLRHILINVRDYVSSIFRRFE
                     SVEGGVSVDPTTATPKLSGKITMSEPTPELRQTGTISVYDLIEMAEEALYEIGTKVWIT
                     FDRLDVAFSENPQLETLAIKTLFRVYNDIKDYDKISLKIFIRDDIWKRISMGGFREASH
                     ITKQVTIRWTEQDLLHLLVSRAVDNDDLIKYMGISKSIVLTNTDSQREFFYNIFPEKVD
                     TGRNPETFKWMISRVKDGLGIIAPRELIHLLNESRDEQIKALETGTTEDSFPNLISRKA
                     LKEALIIVSRVRLEQTIYPEYPHLKPFIESLEEQKTEQDINTLSKILELNLEETRKIVS
                     ELVNIGIFEDRKGTYWTPFLYRGGLRLSQGRED"
     gene            complement(18236..18994)
                     /locus_tag="LRO88_RS22490"
     CDS             complement(18236..18994)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042699.2"
                     /locus_tag="LRO88_RS22490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6602 domain-containing protein"
                     /protein_id="WP_159377170.1"
                     /transl_table=11
                     /translation="MDRESNKRLYVELLRGNFEKILSELDLVYKLTHNGEKGKEAEEIL
                     KNFLKKYLPNKYNVTTGFVHTDMGISNQSDILLYDANNYPPLYSGYANQIIHMGSLRAV
                     IECTMRLNKKKIEEDNKKVSNLKNLYRNDVEIRQSLSKEPLAVLFAYKSEGSILEHLNR
                     LEEKNFDIVFCADGQLYNLIADANEYSNNVVDNLLSGQTVHGYTFTKEQHAFSLFYSYL
                     IDYLNTITSDINKYRMVYEYSKSSIYVDYR"
     gene            complement(19096..19575)
                     /gene="rlmH"
                     /locus_tag="LRO88_RS22495"
     CDS             complement(19096..19575)
                     /EC_number="2.1.1.177"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006364 - rRNA processing [Evidence IEA]"
                     /codon_start=1
                     /gene="rlmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391903.1"
                     /locus_tag="LRO88_RS22495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="WP_003243164.1"
                     /transl_table=11
                     /translation="MNINIVTIGKLKEKYLKQGIEEYTKRLSAYAKIDIIELPDEKAPE
                     NLSDQDMKIIKDKEGDRILSKISPDAHVIALAIEGKMKTSEELADTIDKLATYGKSKVT
                     FVIGGSLGLSDTVMKRADEKLSFSKMTFPHQLMRLILVEQIYRAFRINRGEPYHK"
     gene            complement(19656..19826)
                     /gene="yyzF"
                     /locus_tag="LRO88_RS22500"
     CDS             complement(19656..19826)
                     /codon_start=1
                     /gene="yyzF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003097800.1"
                     /locus_tag="LRO88_RS22500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CxxH/CxxC protein"
                     /protein_id="WP_003219122.1"
                     /transl_table=11
                     /translation="MKQAYYSCEEHIETVLDMYIDDHELPPEIRKIEHTNSLSTACELC
                     GDPAVYIVGNE"
     gene            20010..20423
                     /locus_tag="LRO88_RS22505"
     CDS             20010..20423
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391904.1"
                     /locus_tag="LRO88_RS22505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_046161069.1"
                     /transl_table=11
                     /translation="MRFRWVWLFVIMLLLAGCQPSYWVLEKDRIGEGSPDLEIYANYLQ
                     MHDDVKGYQVFTILEGRKMVIVSLGSSEKDKKLEVSDVKFSPKETIVTVKRKPAPTANE
                     KNPYILIGLDKIEGDLIVQDESGDRFEETDYQQ"
     gene            complement(20457..21683)
                     /gene="fdhA"
                     /locus_tag="LRO88_RS22510"
     CDS             complement(20457..21683)
                     /EC_number="1.2.1.46"
                     /GO_function="GO:0018467 - formaldehyde dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046292 - formaldehyde metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fdhA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391905.1"
                     /locus_tag="LRO88_RS22510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="formaldehyde dehydrogenase,
                     glutathione-independent"
                     /protein_id="WP_014481458.1"
                     /sec_met_domain="ADH_N (E-value: 6.3e-25, bitscore: 85.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.1e-10, bitscore:
                     39.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGMALTGNKAVVYKGKGTVAVEDIGYPELILRDGPGVPKANVNR
                     KCEHGVILKVITTNICGSDQHMVRGRTTAPEGLVLGHEITGEVIETGRDVEFIKKGDIV
                     SVPFNIACGRCVMCKTQKTHVCLNVNPDRPGSAYGYVDMGGWIGGQSEYVMVPYADFQL
                     LVFPDKEQALEKILDLTMLSDIFPTGFHGAYTAGVQTGSTVYIAGAGPVGLAAAHSAQL
                     LGASTVIVGDLNEDRLAQARSFGCETVNVQKHDRLGEQIEQILGEPTVDAAVDCVGFEA
                     SGHGNQGEAPAAVLNSIMDVTQVGGSLGIPGLYVTEDPGAKDADAKTGSLKIRFGLGWA
                     KAHTFVTGQTPAMTYNRNLMKAILSGRAQIAKAVNATVISLDDAPKGYSDFDKGAAKKF
                     VIDPHGTLK"
ORIGIN
        1 ccgtgtccga tatgatcggc agcacataca gacatacgcc gatcgaagac tcagccaagg
       61 aatacagaac attaatgccg attttcatca atctatcaag attattagaa aatcaatata
      121 cacaaattgc agattatcag aggggcttaa tcacacacaa atagtacatg acatgaaggg
      181 gagggcatta ccatgccgtt aatcatcgtt gcacttggga tcttagcatt actatttctg
      241 attatgggct taaaattaaa cacatttatt tccctgctgg tcgtatcgtt cggcgtggca
      301 ctggcactcg ggatgccgtt cgataaagtt gtcagctcca tcgaagcagg aatagggggg
      361 actcttggcc acatcgcgct catcttcgga ctcggtgcga tgctgggcaa gctgatcgcg
      421 gattcaggag gcgcacagcg cattgcgatg acgctcgtca acaaattcgg tgagaaaaat
      481 attcaatggg ccgttgtcat tgcctcattt attattggga ttgcgttatt ttttgaagta
      541 ggactggttc tattaattcc gattgtcttt gcgatttcaa gagaattgaa gatttctatt
      601 ttatttctcg gaatcccgat ggtcgcggca ctatccgtta cacacggttt cctgccgccg
      661 cacccgggac ctacggcgat cgccggtgag tatggcgcta atattggaga agtgctgctg
      721 tacggcttta ttgttgctgt tccgacagtg ctcatcgcag ggccgttatt tacaaagttc
      781 gcgaaaaaaa tcgttcctgc atcatttgcg aaaaacggca atattgcatc actcggcaca
      841 caaaaaacgt ttaaccttga agaaacaccc ggctttggaa tcagtgtctt tactgcaatg
      901 ctcccgatta tcatcatgtc ggtcgcgacc attatcgacc tgcttcaaga aacaatcggg
      961 tttgcagata acggagtttt agcttttatc agattgattg gaaacgcatc gactgctatg
     1021 attatttcgt tattggtcgc agtctataca atgggcatca agcgcaacat tccagtcaaa
     1081 accgtgatgg attcttgttc aactgccatt tcacaaatcg gcatgatgct tttgatcatc
     1141 ggaggaggcg gcgccttcaa acaagtgctg atcaacggcg gtgtcggcga ttacgtagca
     1201 gacttattca aaggaacggc attatcgcca atcattctgg catggctcat cgcggcgatc
     1261 ctgcgcattt ctctaggatc agcgactgtt gccgcactaa gcacaacagg tctggtcatc
     1321 ccgttattgg gccattctga tgttaacctg gcgttagtcg tgctcgcaac aggtgccgga
     1381 agtgtcatcg cttcacacgt caatgatgcc ggcttctgga tgttcaagga atacttcgga
     1441 ttaagcatga aagaaacatt cgccacatgg acattgctgg aaaccattat ttccgttgct
     1501 ggactgggat tcattttatt gttaagttta gttgtatgaa attaagaagg agctgtaaca
     1561 catgttcaat acgattggtg tcataggctt aggcgtaatg ggaagcaaca tcgccttaaa
     1621 catggcaaat aaaggtgaaa acgtcgctgt ctataattac accagagatt taacagacca
     1681 gcttatccaa aagctggatg gacaatctct cagcccgtat tacgagcttg aggactttgt
     1741 tcaatcgtta gaaaaaccaa gaaaaatctt tttgatggtc acagcgggaa aacccgtaga
     1801 ttccgtcatc caatcattaa agcctttgct tgaagaaggc gacgtcatca tggacggagg
     1861 aaactcccac tatgaagaca cagaaagaag atatgacgag ctgaaggaaa aagggatcgg
     1921 ctacctggga gtcggcattt ccggcggtga agtcggcgca ttaacaggac cttctatcat
     1981 gccgggcgga gatcgcgacg tctatgagaa agccgctcct atcctgacaa aaatcgcagc
     2041 ccaagtcgga gatgaccctt gctgtgtcta tatcggacca aaaggggcag ggcactttac
     2101 aaaaatggtg cacaacggca ttgaatatgc cgacatgcag ctgattgcag aagcttatac
     2161 gtttctaaga gaaacgcttc gtctgccgct agatgaaatt gcatctattt ttgaaacatg
     2221 gaatcaaggt gagctgaaaa gctatttaat agagattaca gctgagattt tacgcaaaaa
     2281 agacgaaaaa acaggacagc ctctgatcga tgtcatcctt gataaaaccg gccaaaaagg
     2341 caccggaaaa tggacgagca tgcaggcgat tgataacggc atcccgtcca cgatcatcac
     2401 agagtccttg ttcgcccgct acttgtcatc tttaaaagaa gaacggatgg cagctcaaga
     2461 tgtattagca ggcccggaag ccgaagaaaa acacttggat aaagacactt ggattgaata
     2521 cgtcagacag gctctttaca tggggaaagt atgcgcctat gcacaaggct ttgcccaata
     2581 taagatgtca tctgagcttt acggctggaa tctgccgctc aaagacatcg ccttgatttt
     2641 ccgaggcggc tgcatcatcc gcgctgattt cctaaacgtg atcagcgaag cattcagtga
     2701 gcagccaaat ctggctaacc tgctgatcgc gccttatttc acagataagc tccatgccta
     2761 tcaaacaggc ctgcgaaaag tcgtttgcga gggcatcagc accggaatct ctttcccatg
     2821 cttaactacc gcgctctctt attacgacgg ctaccgcaca gggcgttcca atgcgaacct
     2881 cttgcaggcg cagcgcgatt actttggcgc tcacacgtac gaacggactg atatggacgg
     2941 cgttttccat acgaattggt ctgaataacc tgtcatcaaa aacacggtca gttttcaact
     3001 gaaccgtgtt tttttcttct atcccaaaca acagaagaca taagttatgt tttaaatatc
     3061 ataaacagtg atacaataat agctagaaac aatccccaag atcatcatgt gacagcagct
     3121 tgctgttccg ttctattctg cttttggcca ttgtcctttg cccttgacca tgatgtcata
     3181 aaatgttcaa atgccaaaac ggcctgtcat tctgatttac aaaagtccct gaaaaccttg
     3241 tctaattgag aatcagcctc tcatttgtta taaaagaaat gcataaatcc tacctgtcac
     3301 acctttagta agatgaaaaa aagtaggtta tggcttgaca aaaaatatat attaattaat
     3361 aattcatata taattagaat tattattgaa agcgattatg ctttctaata catttttagg
     3421 aggaatatac attatgtctt taatcggtaa agaagtactt ccattcgaag caaaagcatt
     3481 caaaaacggt gaattcatcg atgtaacaaa cgaagatttg aaaggccaat ggagcgtatt
     3541 ctgcttctac ccagcagatt tctctttcgt atgcccaact gagcttgaag atcttcaaga
     3601 acaatatgct gctcttaaag aattaggtgt tgaagtctac tctgtttcta cagatactca
     3661 cttcgtacac aaaggctggc atgacagctc tgaaaaaatc agcaaaatca cttacgcaat
     3721 gatcggcgac ccatctcaaa cgatctctcg caacttcgat gttcttgacg aagaaactgg
     3781 ccttgctgac cgcggaacat tcatcatcga tccagacggc gttatccaaa ctgttgaaat
     3841 caatgcaggc ggtatcggcc gtgacgcaag caaccttgta aacaaagtaa aagcagctca
     3901 atacgttcgt caaaacccag gtgaagtttg cccggctaaa tgggaagaag gcggcgaaac
     3961 tcttacacct agccttgatc tagtaggtaa aatctaagga gtgcattcaa ttggtacttg
     4021 atgcaaacat caaagcacaa ttaaatcaat atatgcagct aattgagaat gacattgttc
     4081 tcaaagttag cgcaggcgaa gatgacactt ctaaggacat gctggctctc gttgatgagc
     4141 tggcttccat gtcatcgaaa atttcagttg aaaaagctga attaaacaga acgccaagct
     4201 tcagtgtcaa tcgtgtcgga gaagacactg gcgtgacttt cgccggtatc cctctgggcc
     4261 acgaattcac atcattagtg ttggcgctgc tccaagtgag cggcagaccg cctaaggtgg
     4321 accaaaaagt cattgatcag gtgaagaaga tcagcggtga ataccacttc gaatcttata
     4381 tcagcctgac atgccacaac tgtcctgatg ttgtacaagc tttaaacatg atgagcgtgc
     4441 tgaacccgaa cattacgcac acgatgattg acggtgcagc atacaaggca gaagttgaaa
     4501 gcaaaaacat catggcagtg ccgaccgttt acctgaatgg cgaatccttc ggaagcggcc
     4561 gtatgacgct tgaagaaatc cttgcgaaaa tgggcagcgg cgcagatgca tctgagtttg
     4621 ctgacaaaga gccgtttgac gttcttgttg ttggaggcgg acctgctggt gcaagtgcag
     4681 cgatctacac tgcacgtaaa ggcatccgca ctggggttgt cgctgaacgc ttcggcggac
     4741 aggttctcga caccatgagc atcgaaaact tcatcagcgt caaagcgacg gaaggaccga
     4801 agcttgcggc aagtcttgaa gagcatgtga aggaatatga tattgatgtc atgaaccttc
     4861 agcgtgcgaa acgccttgag aagaaagatc tgttcgaact tgaactcgaa aacggcgctg
     4921 ttctgaaaag taaaacagtg atcctttcaa caggtgcacg ctggcgcaat gtcaacgtac
     4981 ctggtgaaca agagttcaaa aacaaaggtg tcgcatactg cccgcactgt gatgggccat
     5041 tgtttgaagg caaagacgta gcggttatcg gcggaggaaa ctctggtatc gaagcagcaa
     5101 ttgaccttgc aggtattgtc aatcacgtta ccgtgctaga atttgcgccg gaactgaaag
     5161 cagacgaagt cctgcaaaaa cgtctctaca gcctgcctaa cgttactgtc gtgaaaaacg
     5221 cacaaacaaa agaaatcaca ggtgatcaga gtgttaacgg catcacatac gtagaccgcg
     5281 aaacaggcga agaaaaacac gttgaacttc aaggtgtatt cgtccaaatc ggtctcgtgc
     5341 caaacacaga atggttagaa ggaacggttg aacgcaaccg catgggcgaa atcatcgtcg
     5401 acaaacacgg cgcaacaagc gtaccaggct tatttgctgc cggcgactgc acagacagtg
     5461 cgtacaatca gattattatt tctatgggat caggtgcaac tgccgctctc ggcgcgtttg
     5521 attacctaat ccgtaactaa tataagaaag ccgcaatatt gccagattgg cagcattgcg
     5581 gctttctttt tctacagaaa aaaaccgaac caggcactac ggtaaaagtg ctcgattcgg
     5641 gccagcttct tatagttcct cgccgttcgt ttgaatgaca tttttgtacc actcaaagga
     5701 atctttctta taccgcttca tggatccgtt tccttcattg tcacgatcaa catagatcat
     5761 gccgtagcgt tttttcattt cgccagttgt gaaggagaca atatcaataa tgccccacgg
     5821 cgtgtagcca attaaatcaa caccatcgta cgtgaccgct tttttcaatg cttcaatatg
     5881 cgattttaaa tattgaatgc gctccggatc atgaaccttg ccgtcctcct ccagcgtatc
     5941 cactgcgcca aagccatttt caacgatgaa taacgggatt tggtatcggt cataaaaacg
     6001 atttaacgta tatctcagcc cggttggatc aatcgcccat ccccagtcac tcgaagtgat
     6061 gtacggattt tcgacaccat tcggcaagcc gccatttaca atatcgtcag tgttatcatt
     6121 tttcacatcg cttttcacag ttgttgacat gtaatagctg aagcctaagt aatcgacggt
     6181 tccgtttctt aaaatctcat catcgccgtc ttcgaatgtg atgttgtagc cttcgcgttc
     6241 aaattccttc aacgcgtagc ttggataata accgcgcacc tgcacatcag ggaagaaata
     6301 gcgctgcctc atttcttctt cagccagcat cacatcttta ggattggagg agaaaggata
     6361 aatcggcacg tgtgatacca tggccccgat ctggaactct ggattgatgt cttttccttt
     6421 tgccactgct aatgcgctcg ccactagttc gtggtgtgcc gtttgataca tgacctcctt
     6481 ggcgttttcg ttttcgccaa ccacaacacc tgaattcgtc cataggaaca acggattgtt
     6541 cacatccatt tggttgttga tctcgttaaa tgtcatccag tacttcactt tctctttgta
     6601 acgggtaaag caagcatctg caaagttgac gaagaagtcc acgactttcc ggtttctgaa
     6661 gccgccatat tctcttgcca ggtgcagcgg catttcaaag tgagacaggg taatgaccgg
     6721 ctcgatccca tgcttcagca attcatcaaa cacatcatca taaaactgca aaccagcttc
     6781 gttcggttca gcctcatcgc ctttcggaaa aatccggctc cagccgatgg acgtccgcag
     6841 gcattttaat cccatttccg caaacaaagc gatatcttcc ttgtatctgt gatagaaatc
     6901 aatggcttca tggtttggat aaaattcgtt ttcttcaatc gtatccgtga tttttctcgg
     6961 cacgccgtgc gcacccgctg tcatcacatc gacgacactc ggccctttac cgccttgatt
     7021 ccatccgcct tcaaattggt gggcagctaa agcaccgccc cataaaaaat ccttcggcat
     7081 gtttcccatg tttaattcct cctcagctta cgactgtaaa tattttttga tgtaatgcac
     7141 tttcctcaat ctcttcaatg aaagctttat caaactcaac aagcacttcg ccttttttga
     7201 cggtatcgcc ttcttttacc ttcaaggaaa aaggcctgcc gtctaatgtc accgtatcca
     7261 gcccgatgtg cgcaagcaat tcgacgctga acgctgaacg caggccaatc gcatgctttg
     7321 taggcgtaac catgacaacc gtaatgacgc cgggatggta gcatcgattt cacgatatcc
     7381 ttcgctttag gggtagaccg cttcagcacc aatcgaagtc tggtagcgca gcgagaagcc
     7441 ccaatcacat tctcttcccc gcctacggcc tctaaaatgt cttttgctag tctcgtataa
     7501 tctctcactt tccccgacat tttcacccac ccctttgttt tggttacgct ttcattataa
     7561 ttgtaccggt ataatttatc aatgccgaaa caaaatatta acgcactaac tatcattgta
     7621 agcggtttat gctataattt tgacaagtga aactaaacga ataaatgagg aatgcgtatg
     7681 ttaaaatacc agcaaatcgc aacggaaatt gaaacatata tagaagaaca ccagcttcag
     7741 cagggagaca aactgccagt cctagaaacc ctcatggccc agtttgaagt cagcaaaagc
     7801 accatcacaa agtccctcga gctattagag caaaaaggcg cgatctttca ggtcagagga
     7861 agcggcattt tcgtcagaaa acataaacga aaaggctata tcagccttct gtcgaatcag
     7921 ggatttaaaa aagatctcga ggatttcaac gtcacctcaa aagtcatcga actggacgtg
     7981 agaaagccaa caccggaagc ggcggaaaac ctgaacatcg gaatggacga ggacatctac
     8041 tatgtcaaaa gggtccgcta catcaacggc cagacccttt gctacgaaga atcctattac
     8101 accaaatcca tcgtgacgta tttaaacaac gaaatcgtct cccactccac cttccattac
     8161 atccgggaag gactggggtt gaagattggt ttttctgatt tgtttctgca cgtgggccag
     8221 cttaatgagg aagaagcgga atatttggga ttagaggctg gactgccgaa gctgtatata
     8281 gaaagtattt ttcacctgac aaatgggcag ccgtttgatt actcgaagat ttcgtataat
     8341 tatgagcagt cgcagtttgt ggtacaggct aatagttttt tattgtgaaa ttcggtatct
     8401 aataggattt cttttaataa ttctccacca aatattatgt tcaaaaaaag ctacttcact
     8461 gtgaagtagc ttcctttatt aaatgcccat tttgatccat ctagttttag aaaagcgaag
     8521 gataatcgca tttatgataa taattgaaac taaatacaaa ataataaata aaacatcatt
     8581 actcccaagt gtcatgttat cagattgcag cactctttct attcggggat acatagtgtt
     8641 acctgcctca aaaggagcaa tgaaaccaaa cgttttattg cttatagcta ctaagataac
     8701 agaagtcatc caataaacga tactgacacc tatactaatt aatatattag gacataacac
     8761 gcttatagtt ccgataatta gaatatactg cagtataact gcagaaaata aaaaaagtaa
     8821 taatgcaaaa tgcgaaaaat catggtacat caacgatatg attagcaggc ctagcgttat
     8881 aaatgcaaaa cattctaaaa ataaaacagc tatcttttta taaaagaaag tatagatgtt
     8941 ctctccaatt aacttgtaaa agagaatatt tttgtttgaa tactctctat taataaagaa
     9001 agctataaca aatgaaaata acatcaaacc aaactgggtc gcaacagtat aggagctaaa
     9061 gaaaaacatt tcaggcgtaa cattgctgac tttatcaatt ccaacaagta aaaaataacc
     9121 cagcaaaaat aaaaatacaa acattgctcc taaaataatg ataactttgt tgctaatact
     9181 ctttttaaac tctaatttca tctcaagccc ccactgtttt attactcatt tatatacact
     9241 tcaattaatt tatccactga atgatattgt tgaatttctt ggtgattaaa tatataataa
     9301 tccccttcta tcgcctttaa atcagacaaa tcatgtgtaa tgttgatgat aatcttctcg
     9361 gggttctcct gaatatactt gtttaagaag ccatgaatct ctataaccgt ttttttgtct
     9421 aatgaattcg ttatttcatc taaaacaata atatttttat cctctaataa gaaactgagc
     9481 aattttaatt tttgcttttg tccatcactc aaatttttga tcagaacttt tccatcaata
     9541 ttatccagat taagtaaatg tgcgatttta tctatcattt ctgcatcaaa ttttttactc
     9601 aaaaagtgta ataaaaagtc cttagaaaca tcattaggta tattcgaaga gctggatatt
     9661 aaagaaacat tttgacgaat atctctgccg attcttttgc tattattcaa caaaaagtct
     9721 ttagcaagct gtgatttacc gactccattt tttccgacaa cgtgattaat tttcccgctc
     9781 gaaaaatgca agtcggtgtc ctgaagtaac gttttgcctt tcacttttaa agtgtaattc
     9841 gctatattca tatacatact cctaggaaat atttgcataa taataaaatg ttctgccttg
     9901 tgatttgtta ctaatgtcta agcttttgag gtacctcttt cgtttccgat ctggaagcgc
     9961 aagaaatgtt tttagatggc taatttggag atcttttact ctagtttaca atatataata
    10021 tccaatgtac aactgaattc actgcaaggc caatccctat aatttgaatc gtaagaacta
    10081 accaatgatt tgtcttaaaa cggctatatt catctaagct cagaaaagct aaaagaattt
    10141 tgtaaccatc agaattcagt attggaatta agttccacaa taaagtagac gagaaaagca
    10201 taaatgccat agttaatgct tcactggaaa atgtaaattg atttattaat tctaatgtgt
    10261 ttattaaaaa ataattgata aacaagccaa ataaatgaac gattatcttt tcatttcttg
    10321 atagcatata ggtttcattc aattggacat aaaaagcagg aaatacataa aaattcagtt
    10381 tgaatcccac tttatcaaag tttttcccga aaaattttaa ggaataaata tgtcccagtt
    10441 catgaagcac tatattcatt ataaagtaaa taactataat tatccacatt ttccagccat
    10501 aaaatactga ggacaatcca ttttgcaatt ttattaaatg aatataattt aatatgaaca
    10561 tgagagccgt aaaggataag aacagataaa aaaactttgg tgatactttc tctttataca
    10621 ttttaaaacg taataattgt tcatctgaca gagaatttaa actattttta tagtattctc
    10681 cgcttttttt gtcttttata aatacgttgt tttgcacaag cacttcatat ttttcatctt
    10741 catactttaa aattttcatt atagtatttt tccatataag gatagaagta gtttattttt
    10801 tctgcagagt tgaataagga accacaaact ccacaaatag aggaaaattc ataaggaatg
    10861 tcaaattcct ctatcttgtt attctctttt aaaatattca aaaaccattt gaatccttct
    10921 tttctaagaa taaataatag caaattggaa tttaactttt ccacggttct ttcgaaactt
    10981 tggttatatt cttcccttag ggttattttc gtttcaaaaa tagcagggga acaacatgga
    11041 taaatttctc catcatgatg atatacaatg tcatatccgg gacaatgtaa ggaatcttca
    11101 tcttcaagac tgtaaaattt atgtatgttt tcttgcttaa ttctagtttt agcagcgcca
    11161 actgatacca ttggaaattt tgttatcttt acacctaaga ttgaatcccc caattcctct
    11221 aaaatatggt tggacatttt gtctttggta actgccatat taagagaaat atcgatatca
    11281 gggtatttcc tgctatgttc taatatgttt ttaatactgg aagacttgac aaatggagca
    11341 tggtactcat cataacttat agtcagtgct atcacattta aagaattcat atcatgaaag
    11401 tactcctgga cctttttctt gctcaaaccc caaaatccat tagagatcaa cgttatttgt
    11461 ttttcatatg gtttaatgat ttccattagt tcttttaaaa atttataatc taaaaaaact
    11521 tccccacctg taaaagaaat cacttgaatg gttttgtttt ttgcaaattc agttactaac
    11581 tctcttatgt attctttttc catcctggtt gttgaagttg gtgaactaga aaaacaacaa
    11641 tggtcacagg atgcattaca ccttgaatct aaattgattg atactgtttt attatacatg
    11701 aaatatcccc caacaaatgg taaaggagag ttagactctc ctttgtaccc ctctaattaa
    11761 tgaccacttc caagaatcca gcgattttct tttgatttta caaaatacca aagatcattc
    11821 acttttgcta acttttgtga ttcatctaat agacccttaa attctaagtt tttcacagtc
    11881 tcattgttag tgttttcctt tttcatatta tccctccttc ttttctaata taaaccaatt
    11941 attctatatg attcaataca tgtcaatata ttgtacctaa aaaatctgaa aaatgtcact
    12001 attcttggta tataaagcct atagtcctct agcccctcta agctataccg aatgaaaggc
    12061 catagtttga tttaaagctt cgtaatgaaa agtaaaacat caatattgac tacactagtt
    12121 aagggatata cagattttaa gtggaagaaa tgaggcaaac aatcttaccc caaaccaacc
    12181 tgcaagatcc tctatggata ctactgaaaa gctgttttaa gctcttgctt accccatttg
    12241 gcatctcttt ctctcgtttc aattgtcata aaaagcagtt atgcggtact atcatataaa
    12301 ggtccaataa tgaaaaccaa tgtcatactt ttaaattcac cttatcatgc acatgatcat
    12361 atataggggt ttattctaaa aaggggatgg acgattttgg aaagcaagta cctagatcta
    12421 ctcgcgcaaa aatacgattg tgaagaaaaa gtggtaacag aaatcattaa tttgaaagcg
    12481 atattgaacc tgccaaaggg caccgagcat tttgtcagtg atttgcacgg ggagtatcag
    12541 gcattccagc acgtgctgcg caatggttca ggacgagtca aagagaagat acgcgacatc
    12601 ttcagcggtg tcatttacga tagagaaatc gatgaattag cagcattggt ctactatccg
    12661 gaagacaaac tgaagttaat caaacatgac tttgatgcga aaccggcatt aaacgagtgg
    12721 tacaaagaaa cgattcatcg aatgattaag ctcgtttcat attgctcctc caagtatacc
    12781 cgctccaaat tacgcaaagc actgcctgcc cagtttgctt atataacgga ggagctgcta
    12841 tacaaaacag aacaagctgg caacaaggag caatattact ccgaaatcat tgatcagatc
    12901 attgaacttg gccaagccga taagctgatc accggccttg cttacagcgt tcagcgattg
    12961 gtggtcgacc atctgcatgt ggtcggcgat atttatgacc gcggaccgca gccggataga
    13021 attatggaag aactgatcaa ctatcattct gtcgatattc agtggggaaa tcacgatgtc
    13081 ctttggatcg gcgcctactc cggttccaaa gtgtgcctgg ccaatattat ccgcatctgt
    13141 gcccgatacg acaacttgga tattattgag gacgtgtacg gcatcaacct gagaccgctg
    13201 ctgaacctgg ccgaaaaata ttatgacgat aatccagcgt tccgtccaaa ggcagacgac
    13261 aacaggccag aggatgagat taagcaaatc acaaaaatcc atcaagcgat tgccatgatc
    13321 caattcaagc ttgagagccc gattatcaag agacggccga actttaatat ggaagagcgg
    13381 ctgttattag agaaaataga ctatgacaaa aacgaaatca cgctgaacgg aaaaacatat
    13441 caactggaaa acacctgctt tgcgacgata aatccggagc agccagacca gctattagaa
    13501 gaagaagcag aagtcataga caagctgcta ttctctgtac agcattccga aaagctgggc
    13561 cgccatatga attttatgat gaaaaaaggc agcctttatt taaaatataa cggcaacctg
    13621 ttgattcacg gctgtattcc tgtcgatgaa aacggcaata tggaaacgat gatgattgag
    13681 gataaaccgt atgcgggccg tgagctgctc gatgtatttg aacgattctt acgggaagcc
    13741 tttgcccacc cggaagaaac cgatgacctg gcgacagata tggcttggta tttatggaca
    13801 ggcgagtatt cctccctctt cggaaaacgc gccatgacaa catttgagcg ctatttcatt
    13861 aaagagaagg aaacgcataa agaaaagaaa aacccgtatt attatttacg cgaagacgag
    13921 gcaacctgcc gaaacatcct ggcagaattc ggcctcaatc cagatcacgg ccatatcatt
    13981 aacggccata cacccgtaaa agaaatcgaa ggagaagacc caatcaaagc aaacggaaaa
    14041 atgatcgtca tcgacggcgg cttctccaga gcctaccaat ccacaacagg catcgccggc
    14101 tacacgctgc tatacaactc ctacggcatg cagctcgtcg cccataaaca cttcaactcc
    14161 aaggcagaag tcctaagcac cggcaccgat gtcttaaccg tgaaacgctt agtggacaaa
    14221 gagcttgagc gaaagaaagt gaaggaaacg aatgttggtg aggaactgtt gcaggaagtt
    14281 gcgattttgg agagtttgcg ggagtatcgg tatatgaagt gagggatgtg gggttcaggg
    14341 aaaatgatat gctcccccaa ggtagacagt agaaataaaa taatctgtat gccctgggga
    14401 atttttttat ttctggaaaa tggtactcgg gaaataagta aataaccata cttttagaat
    14461 gtaatcaggg aaattcttcg gtgaaagagg ttgtgaaaaa atgtgacatt cacaccgact
    14521 caattcgtaa atggagaaca ttacacgaca tagcagtcgt taagagcctg aaacgtctga
    14581 acatcataag ttctactctg ggaaactgaa acgctaccgt gaaggacttc ttatactgaa
    14641 gctacccatt tccagtaaat ccgtgctgaa caaatgggct gagttttata atggtcgtaa
    14701 agcgttaaaa gataaaaaag agaggaagga atcggtttat tgctaaactg agaacgcttc
    14761 attagaagaa ccttacttct tatcaaaaaa aggagaccca cttccctcta ttgttactaa
    14821 ctatggaagg tgttcgaaat agaaaattat cattcctcaa tactcgccat ctttgttttc
    14881 taggtactat tacagatttt cacgtgagat gcttcttaac gagcccaata aattatttta
    14941 tcgtattcaa tatcttcttt ctcctcatta ggatggggac agaaaaacaa cattaattta
    15001 ctttgaacaa cagtgagtaa cagagttata ttagacaata cttccataca caacaaaatc
    15061 acatcataag cgactcaaac agttagacag ccttctcgta tggcagaggg ctttggcaga
    15121 ttaactaccg taaaagaagc ttttcataat tgtctactcg acagggaaaa ggttaatcac
    15181 ttgatttttt tgcatcctaa aattttaatc aaaattcctt ttaaattatt ttcactaatg
    15241 gatgccatgc cgaaaagatt ttaaactata aattagacaa ctaaggtaaa catttattaa
    15301 tggtatagga tattgtgtga atcattgatt aattccttcc ttaacttcat attattttaa
    15361 taagctttaa tcagttttta ttttatcaag tgattgacta accttacttg agattaatat
    15421 tatcagtgca tttgttgatt caaaagccat cctagcttca ttttctgaca cacttgtcct
    15481 tccactatga actatttcat ttcttaatgt atacgcccat ttatgccaat agttatattc
    15541 tttaacagtc aaaatactat tattacctat tattatttta agatattttt taacaaatct
    15601 tcctttatat ttccttcttg aatagcctct ttataatttt ttgtaggtaa tttttctaga
    15661 tctcttcctc ttccaacagg taatttttga atacctatat tctgacatgc attaactagc
    15721 aactctttaa gaaaaacttc aaaagaagta ccaattttca cgacactcag ttcataatta
    15781 ttgttgatat gtccctgttc tttagcttca agcaaaagtt gttgatatag aggaattcta
    15841 ctaccagttt tcaataaatt atttaacttt tctatctttt ctttagttaa gataggtttg
    15901 ttgagttttt ttaagccgtt aaaattaaca gtttctttat aaggtttcaa atttgcgcta
    15961 atcaactcac ctttttgttc cactaaatcg gagtaccaaa tttcaattac aggtgattca
    16021 tttgatcttg gtaaataaat atcattttct tgcgaaacca atctgtattt atttgtaaaa
    16081 tcgtttataa tatcaaatgc agaattatct aataatctaa tgttgtcttc tttatccaaa
    16141 aaatctttgt ttggtatatt aaaggatact tcaaatattg aaaaattagt tggttcaact
    16201 actcctgcac taaaatggtc tttattatta taataatgta tataccttaa tggtatttgt
    16261 tccaatggat cattagtaga tatcttaaga acacttaaat tattattctg attcccatct
    16321 tcttggaata accacgaaag atctttattt gtataagatg atatatttgc tccattaatc
    16381 gtctttactc ttaccaaact tttattccct ttatattgaa caaaaaatcc aatatcttct
    16441 ggaagtgcca atttgatatg aaatagatat cttaacatac aaattgccat tacttatcaa
    16501 ccctctttgt aaaaattagt attttcttaa ctgaattaaa taaaagagta ctaagatcca
    16561 tactcttagt accctattta taatgaatta actaaattta ttcgagtttc ctaaaatcaa
    16621 tcttctcttc cttgagataa ccttagtcca cctctgtata agaagggtgt ccagtatgta
    16681 ccttttctat cctcaaatat acctatatta accagttcac taactatctt tcttgtttct
    16741 tctaaattca actctagaat ttttgagagt gtattaatat cctgctctgt cttttgttcc
    16801 tctaaacttt caataaatgg ttttaagtgt gggtattctg gatatattgt ctgctctaac
    16861 cttactctcg agactattat gagggcttcc tttagtgctt tccggcttat taaattcgga
    16921 aaagagtctt ctgtagttcc tgtttctaat gcttttattt gttcatctct tgattcattt
    16981 agtaagtgaa tcaattctct cggagcgatg attccaagcc catccttaac ccgacttatc
    17041 atccatttaa atgtttcagg gtttctcccc gtgtcaacct tttcagggaa tatattataa
    17101 aaaaattcac gctgtgaatc agtatttgtc agcactatag atttacttat acccatatat
    17161 tttattaggt cgtcattatc tacagctcta ctaacaagta agtgtaacag atcctgttct
    17221 gtccaacgaa ttgtcacctg tttagttata tgacttgctt ctctaaaccc tcccattgat
    17281 attcgcttcc agatatcatc tcggataaaa atttttaaac taattttgtc ataatctttt
    17341 atatcattat atacccggaa taatgttttt atagcaagtg tttcaagttg agggttttct
    17401 gaaaaagcaa catctaatct gtcaaatgta atccaaactt tagttccaat ctcgtacaat
    17461 gcttcttcag ccatctcaat taagtcataa acagaaattg ttcctgtttg tcttagctca
    17521 ggagtaggct ccgacatagt aattttccca gaaagttttg gtgtagctgt agtggggtct
    17581 actgatactc cgccctcaac tgactcaaaa cgtctaaata tgcttgaaac ataatctctt
    17641 acattgatga gaatgtgacg aagacctgaa ccgttcagta atccctcatc ttctagtttc
    17701 gaaataaata aacgtacttt tttataatca tctttatagc tcttaatttt atcaccaatt
    17761 agtgtaagta tatacataaa ccagagatgt ctaaatgact cctcattcaa ttcctgattt
    17821 cctagaactt gcttaaaaac ggttgctcct ctaatatttt cagcaggaat taaaagaata
    17881 tctctttcag taaaaaaact ctccttatgt agtaaatgtc tataaagtgc acttttccca
    17941 gaaccttttg ctccatagac aacatctatc ctatcattta ttaattgttt ccaaatattt
    18001 gtttcaacaa agtaatcagc tagatttgaa tcatcttcag ctactctttc accaaaatgt
    18061 attgatttga gtaattctaa tttataaccc aattaaatct cccccatact taaaattcac
    18121 actagttata aactaatgct atgaaattta acctcaaaaa actataactt taaataatta
    18181 attttatagc cttaagccct tacatactta atgaaaatgt tgaggtgaaa agtatctatc
    18241 tataatcaac ataaattgat gattttgaat attcataaac cattctatat ttattaatat
    18301 cactagttat tgtgttcaga taatctatca aatatgaata aaatagagag aatgcatgtt
    18361 gctctttagt aaaagtatac ccgtgcactg tttgacctga aagcaaatta tcaactacat
    18421 tgtttgagta ttcattagca tcagcaataa ggttataaag ttgtccatcc gcacagaata
    18481 ctatatcaaa attcttttct tctaatcgat taagatgttc taatatactg ccctcagatt
    18541 tatatgcaaa tagtactgct aaaggctctt tacttaaaga ttgtctaatt tcaacatcat
    18601 ttctatacaa attttttaga ttgctcactt ttttattatc ttcttctatc ttcttcttat
    18661 ttagtctcat agtacattca attactgctc ttaaactacc catgtgaatt atttggtttg
    18721 cataccctga atatagagga ggataattat ttgcatcata taaaaggata tcactctggt
    18781 tacttatccc catatctgta tgaacaaatc cggttgttac attatattta ttaggtaaat
    18841 actttttcag aaagttcttt aatatctctt ctgcttcttt tcctttctca ccattatgag
    18901 ttaatttata tactaaatct aattcactta gtattttttc aaaattgcct ctgagaagtt
    18961 caacatataa tcttttatta ctctctctat ccacttgtgg taatttctcc tctcgacatt
    19021 caaataaata gttaataaat actctaaaac tgcacttgtc taaaaatgta gtctatttta
    19081 tattcaaatc ctcctctatt tatgataagg ctccccacga ttaatccgaa aagcccgata
    19141 aatctgctcg actagtatga gacgcatcaa ctgatgagga aatgtcatct tcgagaacga
    19201 tagcttctcg tccgctcgct tcatcaccgt gtcactcaat ccgagtgatc cgccgatgac
    19261 gaaggtgact ttgctttttc catatgtagc cagcttatct attgtatcgg ctagttcttc
    19321 ggatgttttc atttttcctt cgatggcgag ggcgatgaca tgggcgtcgg ggctgatttt
    19381 ggataggatg cggtcgcctt ctttgtcttt tatgattttc atgtcctggt cgcttaggtt
    19441 ttccggcgct ttttcgtccg ggagttcgat gatgtcgatt tttgcgtagg ccgaaagtcg
    19501 tttggtgtat tcttcaatgc cttgcttgag gtatttttct tttagttttc cgattgtcac
    19561 aatattgata ttcacaggtc atccccactt taaaaacaag ttattcatat atgttgtcca
    19621 caattgtgga tatcttttct gtattttgtg taagatcatt cgttccccac tatatatact
    19681 gcggggtctc cacataattc acaggctgtg gataaactgt tagtatgttc gatttttctg
    19741 atttcgggcg gcagctcgtg gtcgtctatg tacatatcca gcaccgtttc gatgtgttct
    19801 tcacaggaat aatacgcttg tttcatgttc aaatcctccg atgtttcttc catttttaca
    19861 attgttctct tctcaatata acctatttat tcacatgtta gtagtgcttc gggctgagtt
    19921 ttatccacaa ttcgacaaac aagctgttga tgactctatt tcgcccgtat gttagtttgg
    19981 atgtaaccga tgtgtgggga ggtttgcatt tgcgctttag atgggtttgg ctttttgtga
    20041 tcatgttgct gcttgctggg tgtcagccgt cttattgggt gttagagaag gatcgaatcg
    20101 gtgaaggcag tccagactta gaaatatacg ctaattatct ccaaatgcat gatgacgtga
    20161 aaggatatca agtcttcacc attttagaag ggagaaaaat ggttattgtg tctctcggaa
    20221 gcagcgagaa agataagaag cttgaagtgt cagacgtcaa attctcacct aaagaaacga
    20281 ttgtaactgt gaaacgaaaa cctgctccta cggcaaatga gaaaaaccct tatattttga
    20341 ttggactgga caaaatcgaa ggggatttaa ttgtccaaga cgaatcagga gatcgctttg
    20401 aagaaacaga ttaccagcaa taaagccggc gttctgagaa cgtccggctt tttcttttac
    20461 ttcaatgtcc catgcgggtc gatgacgaat tttttggctg cgcctttgtc aaagtcgctg
    20521 tagccttttg gcgcgtcgtc cagagaaatg acggtggcgt tgacggcttt tgcgatctgc
    20581 gctctgccgc tcaggatcgc tttcatcaaa ttgcggttgt atgtcatggc aggtgtttgt
    20641 ccggtgacga aggtgtgggc tttggcccag ccgagtccga atcggatttt tagtgagcct
    20701 gttttagcgt ccgcatcctt tgcgccggga tcttcggtca cgtataagcc tggaatgccg
    20761 aggctgcctc cgacctgggt gacgtccatg atcgagttca gcacggcggc aggcgcttcc
    20821 ccttgattgc cgtggccaga tgcttcaaag ccgacacagt ccactgcggc atcaacggtc
    20881 ggttcaccta gtatttgttc aatttgctcg ccgaggcggt cgtgtttttg cacgttgacc
    20941 gtttcacagc cgaagcttct tgcctgtgcc agtctgtctt cgttcagatc gccgacaatc
    21001 acggtggagg cgcctaggag ctgagcggag tgtgcagctg ccaagccgac aggccccgct
    21061 cccgcgatgt aaacggttga acctgtttgc acgcccgctg tgtaagctcc atggaagccg
    21121 gtcgggaaaa tgtcggacag catggtcaaa tcgagaatct tttctaacgc ctgttcttta
    21181 tcagggaata ccaaaagctg aaagtcagcg tatggcacca tgacgtattc agactggccg
    21241 ccgatccagc cgcccatatc gacgtagccg taagcagatc ccggccgatc cggattgaca
    21301 ttcaggcaca catgcgtttt ctgcgttttg cacatcacac agcgtccgca ggcaatattg
    21361 aaaggaacgg atacgatatc gccctttttg ataaattcga catcacgccc cgtttcaatg
    21421 acttctccgg tgatttcatg cccgagcacc aagccttcag gcgccgttgt gcggcctctg
    21481 accatatgct ggtcgcttcc gcaaatgttg gttgtaatga ctttgagaat aaccccatgc
    21541 tcacattttc gattcacatt cgccttcggg acgccgggcc cgtccctcaa gattaactcc
    21601 ggataaccga tatcctccac cgctacagtc cctttgcctt tgtacacaac cgctttgttt
    21661 cctgtcaacg ccattcctcc cattcatgtt tttggactc
//
