LOCUS       NZ_JAJNDF010000004     22583 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Rhodococcus qingshengii strain IEGM 746
            NODE_4_length_562792_cov_213.546577, whole genome shotgun sequence.
ACCESSION   NZ_JAJNDF010000004
VERSION     NZ_JAJNDF010000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rhodococcus qingshengii
  ORGANISM  Rhodococcus qingshengii
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus; Rhodococcus erythropolis group.
REFERENCE   1  (bases 1 to 562792)
  AUTHORS   Elkin,A.
  TITLE     Development of a sustainable strategy for remediation of
            hydrocarbon-contaminated territories based on the waste exchange
            concept
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 562792)
  AUTHORS   Elkin,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-NOV-2021) LAM, Institute of Ecology and Genetics of
            Microorganisms, Ural Branch of the Russian Academy of Sciences,
            Golev Str., 13, Perm, Perm Kray 614081, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-NOV-2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021026075.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 04:42:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,393
            CDSs (total)                      :: 6,335
            Genes (coding)                    :: 6,273
            CDSs (with protein)               :: 6,273
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 21 of 62
            Pseudo Genes (incomplete)         :: 52 of 62
            Pseudo Genes (internal stop)      :: 5 of 62
            Pseudo Genes (multiple problems)  :: 14 of 62
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:48:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 343262
            Orig. end                         :: 365845
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAJNDF010000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22583
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22583
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22583
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12583](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12583)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(595..1785)
                     /locus_tag="LQ424_RS12750"
                     /old_locus_tag="LQ424_12745"
     CDS             complement(595..1785)
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730416.1"
                     /locus_tag="LQ424_RS12750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12745"
                     /product="lipid-transfer protein"
                     /protein_id="WP_030536146.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.8e-07, bitscore:
                     24.9, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKDVAVLGVGMHPWGKWGQSFVKYGVAAARAALADSGVNWQDVD
                     FIVGGETVRNGYGGYVAGATFAQALGWNGARVATSYAACATGAQALDTARARILAGLSE
                     VALVVGADTTPKGFLAPVAGERWDDPDWLRFRLMGMTNPAYFALNARRRIDLYGATAED
                     FANVKVKNARHGLSNPNARYRKEVTVENVLASPVVSNPLHLLDICATSDGGAAILLTSM
                     EYARKMGIAEPVRIKAISTVTPTFPQTIMDMPNFSTDSSSAVPAPERTFKESIGYAAYE
                     EAGISPEDVDVAEVYDLATSVELDWIEDLALCKRGEAEHLLRAGDTSIGGRIPVNPSGG
                     LACFGEAVPAQALAQVCELTWQLRGQAEGRQVEGARIGITANQGLFGHGSSVIVSA"
     gene            complement(1782..2258)
                     /locus_tag="LQ424_RS12755"
                     /old_locus_tag="LQ424_12750"
     CDS             complement(1782..2258)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943075.1"
                     /locus_tag="LQ424_RS12755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12750"
                     /product="Zn-ribbon domain-containing OB-fold protein"
                     /protein_id="WP_037126255.1"
                     /transl_table=11
                     /translation="MSETATPAPNGSVTPAVEGWFTTGDEPALIGTKCQSCGTISFPRE
                     ATFCKNPSCFSEEFDDVELSRSGTVWSYTDAQYQPPPPYIPRSDPYEPFALAAVELPEG
                     IVILGQVADGFGVDDLKVGNTVELVVEPLYTDETGVRTTWRWKPVAAADQELQS"
     gene            complement(2471..4198)
                     /locus_tag="LQ424_RS12760"
                     /old_locus_tag="LQ424_12755"
     CDS             complement(2471..4198)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745838.1"
                     /locus_tag="LQ424_RS12760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12755"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_042451589.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9e-09, bitscore:
                     30.0, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPHVVTQSCCSDASCVYACPVNCIHPTPDEPDFLTAEMLHIDPQA
                     CVDCGACVSACPVDAIVPESKLTDPQRVFLSINADFYKEERPRPLLAKVIPAAHVDKGR
                     PPLRVAIVGSGPSAMYAADELLTQPDVQVNVFDRLPVPYGLVRAGVAPDHQKTKQVTRL
                     FDKIAAQKGFEFYLNVEIGKHISHSELLENHHAVLYAVGASSDRGLGIPGADLPGTASA
                     TDFVAWYNGHPDHADDVFDLSHRRAVIIGNGNVALDVARILTADPEKLAGTDISAHALA
                     ALRKSRVEEVVIVGRRGIAQSAFTVPEFTGLMALPDIELSVGPDDMVLDSATEELAKRG
                     ELPHAVEQKLRLLEALKNRDHVDVGNKRITLRYLLTPTSITGDDQVSGIEFARNALVDA
                     NGTVQIEATGDTETIDTGLVLTSIGYRGVPIPGVPFDERASVIPNENGRVLEAPNGDPA
                     TGVYATGWIKRGPSGFIGTNKSCAQETIRMLVDDFNDGRLTNPVADDSAVDRLVRARQS
                     DIVDREGWHAIDKAELERGAAHDRVREKVLDQVEITSILDAAARVKPARRFGRPVRAR"
     gene            complement(4232..5239)
                     /locus_tag="LQ424_RS12765"
                     /old_locus_tag="LQ424_12760"
     CDS             complement(4232..5239)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943163.1"
                     /locus_tag="LQ424_RS12765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12760"
                     /product="diiron oxygenase"
                     /protein_id="WP_003943163.1"
                     /sec_met_domain="AurF (E-value: 9.1e-115, bitscore: 377.7,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTSPLDKRGEASDDSYNETLRLLSEGSVHKHFDPYLDIDWDSP
                     EFAVVPNDRRWILPAETDPLGAHPWYQSQSEARQIEIGMWRQANVAKVGLQFENILIRG
                     MMQYVFSLPNDSAEARYCTHESVEECNHTMMFQEMVNRIGADAPGMSRPMKMLAPFIPL
                     AAGPFPELFFVGVLAGEEPIDHIQKSILRAGGQIHPIMQSVMAIHVAEEARHISFAHKL
                     LSRRIPLMSRPNRFVLSLLFPIVMRILCDAIVIPPKSFWKQFDIPKSVKKDLFWDLPES
                     RQTLRNYFGDVRMLATDTGLMNRASRLVWKACKMDGRASRFRSEPHRSSHNAAA"
     misc_feature    5426..5440
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.78"
                     /tool="antismash"
     gene            5517..6359
                     /locus_tag="LQ424_RS12770"
                     /old_locus_tag="LQ424_12765"
     CDS             5517..6359
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007533550.1"
                     /locus_tag="LQ424_RS12770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12765"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_073512519.1"
                     /transl_table=11
                     /translation="MIRSILSNLALSPPTRLRSLVPSRGVTLSDKTIVLTGASSGIGEA
                     TAHLLARRGAEMILVARGEENLEHVRDEIHRRGGWAHIVPADLSRGEAVDELAETIADR
                     FGSVDILVNNAGRSIRRTALDSVDRFHDYERTMALNYFGPTRLTLRLLPAMLEAKSGHI
                     INVGTWGVTAGVMPRFSAYHASKSALSAFGRSLGAECHGTGVDVTTVQFPLIRTPMIAP
                     TADYVSQPALTADQAASWILRAINTRPVELYPRYAGLLRAIDVVSPSATDALVRRAGI"
     misc_feature    5519..5537
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.55"
                     /tool="antismash"
     gene            complement(6456..7694)
                     /locus_tag="LQ424_RS12775"
                     /old_locus_tag="LQ424_12770"
     CDS             complement(6456..7694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745836.1"
                     /locus_tag="LQ424_RS12775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12770"
                     /product="HNH endonuclease signature motif containing
                     protein"
                     /protein_id="WP_230793200.1"
                     /transl_table=11
                     /translation="MDSRDAWQLDGEGLKGEVLDLVRVRHELQSRMVLLIVEMFSREVL
                     GGKGFRAIAQWLHGSTNLEIGECSLLVGLARLLMLEPVVGDAFHRGDVDALKARQVASF
                     CQHPPKNMTPADVDKARGILLGLASQNIADCDAVRAAIRRIEKQYGKREDGVPVGEDSE
                     RNEFYASKGLYGRVTVKGDLDAINGARLITLLSSLSAPTPEKDGVKDTRTPALRRADGF
                     CELLRRYERAGLGPIEGGVKPHITVTASAKDMTDLQALKDLLPSTQELGFAWTDWVGPI
                     SIDTARMLACDCTVTRILLDENGVPLDCGKEARTATVPQRRALAVRDGGCAFPGCGTPS
                     GWCDAHHIVHWNDGGPTDLDNLVLLCGHHHRTMHHTEWRVEIGPDRKTVFYPPMSIDPY
                     QQPIGGNSPPTAA"
     misc_feature    complement(7708..7723)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.66"
                     /tool="antismash"
     gene            complement(7757..8743)
                     /locus_tag="LQ424_RS12780"
                     /old_locus_tag="LQ424_12775"
     CDS             complement(7757..8743)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LQ424_RS12780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LQ424_12775"
                     /product="hypothetical protein"
                     /protein_id="WP_144245891.1"
                     /transl_table=11
                     /translation="MIFLLILTAALSGWFVQRSGESWDFGDICSRWYDGGGSCRADTAL
                     TLTTLLVLLLPFASGMLVGVTTFARDFEQGPENLDFLESTSLVRWYFLRVLVVFVPITL
                     AMAVLGLVLGWTQTLGRGQAATNEATSFSLMEFPNFQTTGIVVGAYTFLAMTTGSAAAL
                     LIRNTVFAMVMTLLAFLIVPVALSATMREHYLAPDTEVQPIDGLARAAEYAPSPYENLD
                     SRWVIDAGFADTDGNMIDADYTMCWGSDNSDRKQQDLEVDNCLREQGIDHYAVIYHPQS
                     RYWQFQFIETAVMLSCSGLMVALAFVGARGLRRRPAYNRLSEMSKSI"
     misc_feature    8963..8976
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            9228..9362
                     /locus_tag="LQ424_RS31940"
     CDS             9228..9362
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LQ424_RS31940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_256082940.1"
                     /transl_table=11
                     /translation="MNSSDLGSVSALLPMMLTAFKSIITMPFALSVDFGLDVPFNPFK"
     CDS             complement(9750..9869)
                     /gene="allorf_353012_353131"
                     /locus_tag="allorf_353012_353131"
                     /protein_id="allorf_353012_353131"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MTMDAILSLQDLSVAAGNVGDAGQLEQNAAISSLSFFCL"
     CDS_motif       complement(9807..9869)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTMDAILSLQDLSVAAGNVGD"
                     /locus_tag="allorf_353012_353131_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9750..9806)
                     /prepeptide="core"
                     /locus_tag="allorf_353012_353131_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="0.20"
                     /molecular_weight="1845.1"
                     /monoisotopic_mass="1843.9"
                     /core_sequence="AGQLEQNAAISSLSFFCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTMDAILSLQDLSVAAGNVGD"
                     /leader_location="[9806:9869](-)"
                     /alternative_weights="1863.1"
                     /alternative_weights="1881.1"
     gene            complement(10001..12583)
                     /gene="lanKC"
                     /locus_tag="LQ424_RS12785"
                     /old_locus_tag="LQ424_12780"
     CDS             complement(10001..12583)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745831.1"
                     /locus_tag="LQ424_RS12785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12780"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_042451585.1"
                     /sec_met_domain="micKC (E-value: 1.5e-194, bitscore: 643.4,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.5e-14, bitscore: 49.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.1e-06, bitscore: 23.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6e-06, bitscore: 20.3,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYVAFTRADPHFYDRIRTVTRPDTSTDQHFIPAKSVDWSLWR
                     RGPQSGPWNYFQPPDGLLPEQGWKIHCSATQANAQELLDTVSVYCGHNHVPFKFLRTAA
                     DLMLSNSKQANRTSSGKFITIYPADGVATQRVITELDKLVTGADGPYILSDVRWNRGPL
                     YLRYGAYLPMQTYDSFGDRVPAIRRPDGSLEPDVRGTSFRTPDWVQIPDFVRAQQDKLK
                     SHDEFPYSINEALHFSNSGGIYSAFDDAGIDLVIKEGRPFTAPDANGRYAIDRIRNEYD
                     KLTHLADNPYAPSAIRLFEREGHHFLVTERAAGTPLNQEVALRHPLIRADQTLSSRTEY
                     RTWALDIAQQLTTAVESFHNAGIVHADLHPGNVMCSPSGIRIIDFEMAHNIDEHPPRST
                     GAPGYTAPRQLTGIAADRYSLGCIELGLFVPLTTLFPLDRNKIPELIDYAVSRFDLPRA
                     FGASLYSMLDVQAPAPKNRPHRWDTSSNETLQRTAALLRCGILASLDLARADRLFPGDI
                     AQFEVNGYGIAHGSCGNLLADVLPADTLESVLEWTEHQVDSDTQPKFGFFDGLAGAVHT
                     FRHHGRHSTADRWVETLRRAPLDDIDSSLFSGLSGIGCLLLEESVSRPTVSPTLAVVTE
                     TLRERISAARLHVRDAGGTPWAVAGRGGLMRGPSGQALFWTRHYELSGDPRSLEHARQL
                     VDIDLSVMSMCPDGSMQLREERRTMPYLGSGSVGVGLVLLQLLRHVDEPRYAAAVRAIS
                     RAATVEFTAQAGLLNGRAGLMLFLSELSKTPYAGADCEQTLAQQFQLLGLHSLNHAGGL
                     HFPGEQNLRLSTDWATGSAGILALLRYTGSATARQSFPLMCASNCHIA"
     gene            12952..14145
                     /locus_tag="LQ424_RS12790"
                     /old_locus_tag="LQ424_12785"
     CDS             12952..14145
                     /EC_number="2.3.1.16"
                     /GO_function="GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005264857.1"
                     /locus_tag="LQ424_RS12790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12785"
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="WP_030536138.1"
                     /transl_table=11
                     /translation="MTKAVIVDVVRIASGKGKPGGALSGTHPVELMAHVLRSITSRNGL
                     DPALVDDVIGGCVGQAGEQALNITRSAVLSAGFPESVPATTIDRQCGSSQQAAHFAAQG
                     VIAGAYDIVIAAGVESMSRVPMGTTTMGKDASGPGVAARYPEGLVNQGISAELIAAKWK
                     LDRDALDAFSAQSHQRAAEAAAKGLFDKEILPISVTNAAGETVSHIVDETVRASTTAEG
                     LAGLKPSFYSEKYAQRFPEAQWSITPGNSSPLTDGASAALIMSEEMASKLGLTPRARFH
                     SFSVAGDDPIFMLTAPIPATHKVLARAGLSIDDIDTYEVNEAFAPVPLAWAHEFGADPA
                     KLNPWGGAIALGHALGSSGTRLLTTMVNHLEATGGRYGLQTMCEGAGMANATIIERI"
     gene            14174..14935
                     /locus_tag="LQ424_RS12795"
                     /old_locus_tag="LQ424_12790"
     CDS             14174..14935
                     /NRPS_PKS="Domain: PKS_KR (6-163). E-value: 4.9e-13. Score:
                     41.3. Matches aSDomain:
                     nrpspksdomains_LQ424_RS12795_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003875437.1"
                     /locus_tag="LQ424_RS12795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12790"
                     /product="3-hydroxyacyl-CoA dehydrogenase"
                     /protein_id="WP_003942978.1"
                     /sec_met_domain="adh_short (E-value: 4.1e-31, bitscore:
                     103.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVNDSVAVVTGGASGLGLATTKALLADGASVVIIDLPSSNGEAI
                     AKELGDRVRFAAADVTDEAAVTAALDVAESLGPLRVAVNCAGIGNAVKTVSKKGAFPLD
                     AFKKVIDVNLIGTFNVLRLAAERISKTEPIDGERGVIINTASVAAYDGQIGQAAYSASK
                     GGVVGMTLPIARDLASLLIRVNTIAPGLFKTPLLAGLPEAAQASLGQQVPHPSRLGDPS
                     EYGALAAHIVSNPMLNGETIRLDGAIRMAPR"
     aSDomain        14192..14662
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LQ424_RS12795_PKS_KR.1"
                     /evalue="4.90E-13"
                     /label="LQ424_RS12795_PKS_KR.1"
                     /locus_tag="LQ424_RS12795"
                     /protein_end="163"
                     /protein_start="6"
                     /score="41.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGGASGLGLATTKALLADGASVVIIDLPSSNGEAIAKELGD
                     RVRFAAADVTDEAAVTAALDVAESLGPLRVAVNCAGIGNAVKTVSKKGAFPLDAFKKVI
                     DVNLIGTFNVLRLAAERISKTEPIDGERGVIINTASVAAYDGQIGQAAYSASK"
     CDS_motif       14198..14266
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LQ424_RS12795_0001"
                     /evalue="7.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="LQ424_RS12795"
                     /protein_end="31"
                     /protein_start="8"
                     /score="15.3"
                     /tool="antismash"
                     /translation="VVTGGASGLGLATTKALLADGAS"
     gene            14949..15575
                     /locus_tag="LQ424_RS12800"
                     /old_locus_tag="LQ424_12795"
     CDS             14949..15575
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730441.1"
                     /locus_tag="LQ424_RS12800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12795"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_042451583.1"
                     /transl_table=11
                     /translation="MTGEVESVSSVAVDWRSFPPLVMTDILTASLELFDENGYHGTTVR
                     QIANRVGVTVPALYYHHANKEAVLVALFEVSMSELNTRTEAAEAEAGENPVRRFALVVE
                     AIVLYMTHRSRHAALDTEIRHVSPESRSRYAASRKRLELLMRRIVDDGVASGDFAVTDT
                     EETVRAILGMAQSLPRWFQTGGPMSPSQLAQKYVDIAFHTVGYRP"
     gene            complement(15662..17284)
                     /locus_tag="LQ424_RS12805"
                     /old_locus_tag="LQ424_12800"
     CDS             complement(15662..17284)
                     /NRPS_PKS="Domain: AMP-binding (27-436). E-value: 8e-83.
                     Score: 270.2. Matches aSDomain:
                     nrpspksdomains_LQ424_RS12805_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003943212.1"
                     /locus_tag="LQ424_RS12805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12800"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_042451581.1"
                     /sec_met_domain="AMP-binding (E-value: 1e-95, bitscore:
                     315.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSTMQDAPLSIAQLLRHGASVHGASEVVTWTESGPRRVSYADVG
                     KRCAQLAHALRGLGVEGDERVATFMWNNSEHLEAYLAIPSMGAVLHTLNIRLFPEQLIH
                     VANHAEDRVIIVDPSLIPLLSPQLPSLTTVKHIVVTGSSTAGLEAPEGVQVHTYEGLIA
                     DQPTEFDWPEVDELSAAAMCYTSGTTGDPKGVVYSHRSIYLHSMQVCMSDGPNLAQGDR
                     ALAVVPQFHAMSWGLPYAAFMIGASLIMPDRFLQPAPLAAIIASEQPTFAAAVPTIWQG
                     LHLYLEQNPQDISSMREVLIGGSAVPPALMHAFEADHNVSVLHAWGMTETSPLGSVARP
                     PAGVTGDAMWKYRYSQGRFPASVEARLIDDDGKVVAHDGVSVGELEVRGPWITGSYYGV
                     DAEDKFNDGWLKTGDVGSITADGFLSLSDRSKDIIKSGGEWISSVDLENAVMGHPDVTE
                     AAVIGVPDEKWDERPLVAVVLRAGSETTMSELQQYLSDKVAKWQLPENWAVVQEVPKTS
                     VGKFDKKRLRADYHEGGLEVTRL"
     aSDomain        complement(15977..17203)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LQ424_RS12805_AMP-binding.1"
                     /evalue="8.00E-83"
                     /label="LQ424_RS12805_AMP-binding.1"
                     /locus_tag="LQ424_RS12805"
                     /protein_end="436"
                     /protein_start="27"
                     /score="270.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="VVTWTESGPRRVSYADVGKRCAQLAHALRGLGVEGDERVATFMWN
                     NSEHLEAYLAIPSMGAVLHTLNIRLFPEQLIHVANHAEDRVIIVDPSLIPLLSPQLPSL
                     TTVKHIVVTGSSTAGLEAPEGVQVHTYEGLIADQPTEFDWPEVDELSAAAMCYTSGTTG
                     DPKGVVYSHRSIYLHSMQVCMSDGPNLAQGDRALAVVPQFHAMSWGLPYAAFMIGASLI
                     MPDRFLQPAPLAAIIASEQPTFAAAVPTIWQGLHLYLEQNPQDISSMREVLIGGSAVPP
                     ALMHAFEADHNVSVLHAWGMTETSPLGSVARPPAGVTGDAMWKYRYSQGRFPASVEARL
                     IDDDGKVVAHDGVSVGELEVRGPWITGSYYGVDAEDKFNDGWLKTGDVGSITADGFLSL
                     SDRSKDIIKS"
     CDS_motif       complement(16688..16744)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LQ424_RS12805_0001"
                     /evalue="4.50E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="LQ424_RS12805"
                     /protein_end="199"
                     /protein_start="180"
                     /score="22.3"
                     /tool="antismash"
                     /translation="AMCYTSGTTGDPKGVVYSH"
     gene            complement(17386..19071)
                     /locus_tag="LQ424_RS12810"
                     /old_locus_tag="LQ424_12805"
     CDS             complement(17386..19071)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019745827.1"
                     /locus_tag="LQ424_RS12810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12805"
                     /product="dihydroxyacetone kinase family protein"
                     /protein_id="WP_042451577.1"
                     /transl_table=11
                     /translation="MFMRSAKTFVPDALRGLIASTDDIAWNPDPGYLTRARPLPRGRVA
                     LVSGGGSGHEPMHAGFIGEGMLTAVCPGLVFSSPNALQIHEGSKAADAGGGVLHIVKNY
                     TGDVMNFGIARELLREDKIDTDVVLVDDDVATERADGSGPGRRGTAATIVVEKVCGASA
                     ARGDDLAEVTRIGQHVAHSARSMAVALRPCTLPGADEPSFDLPAGQMELGIGIHGERGT
                     ERVDALPAPELVRRLTDPIIKSLSLAEGDRVIAVVNGLGATHPLELQLLFAELGDYLDE
                     QGIHIERTLIGAFVTALNMAGASITLVRTDKEILELWDAPTKAPAWPNAIAREYTGMGT
                     RESFGPTFTPDTSRTAESSFVGSWIADWAEKVLDQEPALTDLDRRAGDGDFGTNMVAAL
                     DQLDISAIRDTYSTATIFDAVSQAYLGHAGGTSGALFGIWFRHFFRVAADSADSELDLG
                     AIAAAARAGLDNITSLGGARVGDKTMVDAIVPAVESLEQSVSSEADRDAALASAAEAAA
                     AGAESTETMLANRGRASYVGEAARGVVDPGALLIAWFFASAVGH"
     gene            19126..19989
                     /locus_tag="LQ424_RS12815"
                     /old_locus_tag="LQ424_12810"
     CDS             19126..19989
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730450.1"
                     /locus_tag="LQ424_RS12815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12810"
                     /product="patatin-like phospholipase family protein"
                     /protein_id="WP_042451574.1"
                     /transl_table=11
                     /translation="MDGVKLGLVLAGGGVAGIAWETGFLLGLQDKSPDTAAALLTADVL
                     IGTSAGSTVSAQIASGVTLQELFDAQTAEATGEIDPKVDVEVLGQMFVDAIAGSQDRAE
                     QLRFLGEAAMRADTVEPAVRRAVIEARLPNRLWPDRELRIPAINAQTGELRVFGNADGV
                     ELIDAVGASCAVPGVWPVVVIEGERYMDGGMASGSNVHLAADCDVVVVLSPAADPAPNL
                     LGGSLREEIDVMTPLPVLPVFADYAVVEAIGTNSLSPTTRRPAAELGREQGRRTADEIA
                     AFLVTA"
     gene            19986..20840
                     /locus_tag="LQ424_RS12820"
                     /old_locus_tag="LQ424_12815"
     CDS             19986..20840
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730453.1"
                     /locus_tag="LQ424_RS12820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12815"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_042451573.1"
                     /transl_table=11
                     /translation="MSAARIAVVVRPEQSPEDLVRHARYADEVGIDEVWLWEDCFFGGG
                     IATAATVLAETDRVGVAIGVLPTPMRNTAITAMEISALARVHPDRLRVGFGHGVQSWMR
                     QIGAKAESPLTLLREQFGAVERLLGGESVTVSGRYVNLTDVTLAWPPETVPQLLVGATG
                     PKTLALSGELAQGTVLSGGTTPDGVRRAIAHIGASDHEVVVYVICAFGSGGRERALAEA
                     AASDSESPEDAIAVGNAAEVAAATRRWVAAGATTVVLQPTVDEPDVREFIRFVAQEVQP
                     LVA"
     gene            complement(20842..21852)
                     /locus_tag="LQ424_RS12825"
                     /old_locus_tag="LQ424_12820"
     CDS             complement(20842..21852)
                     /NRPS_PKS="Domain: Beta_elim_lyase (6-289). E-value:
                     8.8e-77. Score: 250.1. Matches aSDomain:
                     nrpspksdomains_LQ424_RS12825_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730456.1"
                     /locus_tag="LQ424_RS12825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_12820"
                     /product="low specificity L-threonine aldolase"
                     /protein_id="WP_003942934.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1e-07, bitscore:
                     26.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSYIDLRSDTVTKPDAEMRKAMADAEVGDDVLDHDPTMAALEE
                     EVAHTLGLPAALWVPSGSMGNLIALMLHLHRGDQFLAPEHSHVLGSELGTAAWLAQGMP
                     MALPHDGGPGRPTPETVVKAAGSPGPYFALNTTLLCLENTHNFAGGAVMNPTEWTKLVD
                     AARSRGLKIHLDGARLWNAAAALDVSPTELTSGADTVQVCLSKGLGAPVGSILAASPEL
                     ITEARRIRKMLGGGVRQGGVLAAAGIVALRSQARLSDDHDNAQRLASGLRERGWAVDEP
                     ATNIVLAATADPSVTVAQLAAVDVGAVTVAGKVRFVTHRDVSTADIDAVLSRVTF"
     aSDomain        complement(20986..21834)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LQ424_RS12825_Beta_elim_lyase.1"
                     /evalue="8.80E-77"
                     /label="LQ424_RS12825_Beta_elim_lyase.1"
                     /locus_tag="LQ424_RS12825"
                     /protein_end="289"
                     /protein_start="6"
                     /score="250.1"
                     /tool="antismash"
                     /translation="DLRSDTVTKPDAEMRKAMADAEVGDDVLDHDPTMAALEEEVAHTL
                     GLPAALWVPSGSMGNLIALMLHLHRGDQFLAPEHSHVLGSELGTAAWLAQGMPMALPHD
                     GGPGRPTPETVVKAAGSPGPYFALNTTLLCLENTHNFAGGAVMNPTEWTKLVDAARSRG
                     LKIHLDGARLWNAAAALDVSPTELTSGADTVQVCLSKGLGAPVGSILAASPELITEARR
                     IRKMLGGGVRQGGVLAAAGIVALRSQARLSDDHDNAQRLASGLRERGWAVDEPATNIVL
                     AA"
ORIGIN
        1 aagacggttg cggacatcga cggacctgtc gtgctcgtcg gtcactcgta cggcggcgcg
       61 gtgatcacca atgttcacga cccgaaggtg cagtcgttgg tgtacatcgc tgcgtttgct
      121 ccggttcagg gtgagccggt gcagatcacg atcgatccca tcaggtttcc tggcagccaa
      181 ttgcttcctc cggctctggg attgaagatc gtcgacgatc ctcacgcgat cggcgggaag
      241 aacgtcgacg gctacgtcac ggacgagtat ttccattccg tcttcgctca ggatgtttcc
      301 gacgagacag cggcaacgat gttggcgcat cagaagtctg cggctttgtg ggcgaacctc
      361 gagctcggcg ggccaccgtc gtgggcgaac acaccgagct ggtatctggt tgccggtgag
      421 gatcgcgtga tccccgcatc ggcgcagcgg ttcatggcaa accggatggg cgcgaacacc
      481 agcgaactcc cgacctccca tgcctcgctg gtctcacagc caggggcagt ggcagacgtg
      541 atcgtggcgg ccgctcacgg gtgagtgtgc gaccgccacg aaagtagaac agggtcaggc
      601 ggaaacgatt accgaggagc cgtgtccgaa cagaccttgg ttggcggtga taccgatgcg
      661 ggcgccttcg acctgacggc cttcggcctg tccacgaagc tgccaagtga gctcgcacac
      721 ctgcgcaagt gcctgtgcgg gaacggcttc gccgaagcac gcgagaccgc cggacggatt
      781 gaccgggatg cggcctccga tactggtgtc acccgcacgc aggaggtgct cggcctcgcc
      841 ccgcttgcag agggcaaggt cttcgatcca gtccagttcc acggaggtag cgaggtcgta
      901 gacctcggcg acgtcgacgt cctcgggaga gatcccggct tcttcgtatg cggcgtagcc
      961 gatggattcc ttgaacgtgc gctccggagc gggaacggcg gagctggaat cggtggagaa
     1021 gttcggcatg tccatgatcg tctgggggaa cgtcggcgtg accgtcgaaa tagccttgat
     1081 gcgaacaggt tccgcgatgc ccatcttgcg ggcgtattcc atcgacgtca gcaagattgc
     1141 ggcgccgccg tcggacgtcg cgcagatgtc gagcaggtga aggggattgg acaccacggg
     1201 ggaggccaac acgttctcga cggtgacttc cttgcggtag cgcgcattcg gattgctcag
     1261 cccgtgcctg gcgttcttga ccttcacgtt ggcgaaatcc tccgcggtgg cgccgtagag
     1321 gtcgatgcga cgacgcgcgt tgagcgcgaa gtacgccggg ttggtcatac ccatgaggcg
     1381 gaagcgcagc cagtccgggt cgtcccaacg ctcaccggcg acgggagcga ggaagccctt
     1441 cggcgtggtg tcggcgccga cgaccagggc aacttcgctg aggccggcca ggattcgtgc
     1501 gcgagcggtg tcgagtgcct gggctcccgt cgcacacgcg gcgtacgacg tggcgacgcg
     1561 agcgccgttc cagccgagtg cctgcgcgaa ggtggctccg gcgacgtatc cgccgtaccc
     1621 gttgcggacg gtctcgccgc cgacgatgaa gtcgacatcc tgccaattca cacccgaatc
     1681 ggcgagcgcg gcgcgagcgg ccgcaacgcc gtatttcacg aacgactgcc cccacttgcc
     1741 ccaggggtgc ataccgacac cgagtactgc gacgtccttg ctcatgactg caactcctga
     1801 tcagctgcgg cgacaggctt ccatcgccac gtcgtacgta ctccggtttc gtcggtgtac
     1861 agcggctcga caaccaattc gacggtattg ccgaccttga gatcgtcgac gccgaatccg
     1921 tcggccacct ggccgaggat gacgatgccc tcgggcagtt cgactgctgc gagagcaaaa
     1981 ggctcgtacg gatccgagcg cgggatgtac ggcggcgggg gctggtactg cgcgtcggtg
     2041 tacgaccaga cagtgccgct acgggagagt tccacgtcgt cgaactcctc gctgaagcag
     2101 ctcgggttct tgcagaacgt cgcctcacga gggaaggaaa tggtgccgca ggattggcac
     2161 ttcgtgccga tcagagcagg ttcgtcgccg gtggtgaacc aaccctctac tgcaggcgtc
     2221 acactcccgt tcggcgccgg cgttgcagtc tcgctcatgc aatcctcatc tggttggcga
     2281 gcctgatccg ggggatcgtg ggcccgctgt gccgcttact ggaacaggtt gcagtattac
     2341 acgatttcgg ccgctgacgg gcaaaaattt tcgctgagtg ggacgctgcc ggaacgcaga
     2401 cggccccgcc gggcagacga gtctgcaggc ggggccgtgt gcgtgaaagt agctgtttac
     2461 ctgtagcgga tcagcgagcg cgaacgggtc gaccgaatcg acgcgccggt ttcacccggg
     2521 ccgcagcgtc gaggatggag gtgatctcga cctgatccag aaccttttcg cggacacggt
     2581 cgtgcgcagc gccgcgttcc agttccgcct tgtcgatggc gtgccagccc tcgcggtcga
     2641 cgatgtcgga ctgtcgcgcc cggaccagac gatcgactgc ggagtcgtcg gcgaccgggt
     2701 tggtcaggcg tccgtcgttg aagtcgtcga cgagcatcct gatcgtttcc tgcgcgcagg
     2761 acttgttggt gccgatgaac ccactcggtc cgcgcttgat ccaaccggtc gcgtagaccc
     2821 cggtggcggg atcaccgttc ggagcttcga ggactcggcc gttctcgttc ggaatgaccg
     2881 acgcacgctc gtcgaacggg acgccgggga tgggcactcc gcggtagccg atcgaggtga
     2941 ggaccaagcc ggtatcgatg gtctcggtat cgccggttgc ttcgatctgc acggttccgt
     3001 tggcgtcgac aagagcgttg cgagcgaact cgattccgct cacctgatcg tcgccggtga
     3061 tcgaggtcgg cgtgagcagg tagcgcaacg tgatgcgctt gttgccgacg tcgacgtgat
     3121 cgcggttctt cagggcttcg aggagacgca acttctgctc gacggcatgc gggagttcgc
     3181 cgcgttttgc cagttcttcg gtggccgagt cgagaaccat gtcgtcgggt ccgacagaga
     3241 gttcgatgtc cggcagtgcc atcaggccgg tgaactcggg gaccgtgaac gcggactgcg
     3301 cgattccgcg tcgacccaca atgacaactt cttcgacgcg actcttccgc agagcggcga
     3361 gtgcgtgagc ggagatgtcg gtaccggcca acttctcggg atcggccgtc agaatgcgag
     3421 cgacgtcgag cgcgacattt ccgtttccga tgatgaccgc gcggcgatgt gagaggtcga
     3481 agacgtcgtc ggcgtgatcg gggtggccgt tgtaccaggc tacgaagtcg gtggccgagg
     3541 ccgtgccagg cagatcagcg cccggaatgc cgagaccacg gtcggacgaa gcgccgactg
     3601 cgtagagcac cgcatggtga ttttcgagca gttcgctgtg cgagatgtgc ttgccgatct
     3661 cgacgttgag gtagaactcg aaaccctttt gtgcggcgat cttgtcgaac aagcgagtga
     3721 cctgcttggt cttctgatgg tccggagcaa cgccggcgcg aaccaagccg taaggcacag
     3781 gaaggcgatc gaagacattg acctgcacgt caggctgagt cagcaactcg tccgcggcgt
     3841 acatcgccga cggtccggaa ccgacgatcg caacgcgcaa cggcggtcgg cccttgtcga
     3901 cgtgggctgc cgggatgacc ttggcgagaa gcggcctggg tcgctcttcc ttgtagaagt
     3961 ccgcattgat ggacaggaag actcgctgcg ggtcggtcag cttcgactcg gggacgatgg
     4021 cgtcgaccgg gcaggccgaa acgcatgcgc cacagtcgac gcaggcctgc ggatcgatgt
     4081 gcagcatctc ggcggtgagg aagtccggct cgtccggcgt cggatggatg cagttgaccg
     4141 ggcaggcgta gacgcacgag gcgtcgctgc aacaggactg cgtgactacg tgtggcatgg
     4201 cgctatgagt ccgatctcga ctgtccggga gctacgcggc ggcgttgtgc gagctgcggt
     4261 gaggttcgct acggaagcgt gatgcgcggc cgtccatctt gcaggccttc cacaccaggc
     4321 gcgaggcacg gttcatcagg ccggtgtcgg tggccagcat gcggacgtca ccgaagtagt
     4381 tgcgcagggt ctggcgcgac tcgggcagat cccagaacag gtcctttttc acggacttcg
     4441 ggatgtcgaa ctgcttccag aaggacttcg gcgggatgac gatggcgtca cagagaatgc
     4501 gcatgacgat cgggaacagc agcgagagga caaaccggtt cgggcgtgac atcagcggga
     4561 tgcggcggct cagaagcttg tgcgcgaacg agatatgacg cgcttcctcg gctacgtgga
     4621 tggccatgac cgactgcatg atcgggtgga tctggccgcc ggcgcgcagg atgctcttct
     4681 gaatgtggtc gatgggctct tcaccggcga ggacaccgac gaagaacagt tcggggaacg
     4741 gacccgcagc gagggggatg aagggtgcaa gcatcttcat cggacggctc atcccgggag
     4801 cgtcggcacc gatgcggttg accatctcct ggaacatcat cgtgtggttg cactcttcga
     4861 ccgactcgtg cgtgcagtag cgcgcctcgg ccgaatcgtt gggcagtgag aagacgtact
     4921 gcatcatgcc gcggatcagg atgttctcga attggagacc gaccttcgcg acattggcct
     4981 ggcgccacat gccgatttcg atctgcctgg cctcggactg cgactggtac cacgggtgtg
     5041 cgcccagcgg gtcagtctcg gccgggagga tccagcggcg atcgttcggg acgacggcaa
     5101 actcggggga gtcccagtcg atgtcgaggt acgggtcgaa gtgcttgtgc accgagccct
     5161 cggacaggag tcgaagcgtc tcgttgtacg agtcgtcgga tgcttctccg cgcttgtcga
     5221 gcggcgatgt gagcgtcatg gcgtctcctc ttcgtttcgg tcaccgctgg tatttctcgc
     5281 ggtgttcggt ggaatcgagg gccggttgtg tgatcgctgg cactcggtct ggatttaatg
     5341 taacccgagg tatcaggaaa agctagtggc agatactcct gaatcccgac gaattcttga
     5401 cacggccgaa acggcgccat aacttacttt tgagtaattt ccgcggtgcg tccgaagtgg
     5461 gctgttcagg gacgggttcg caccgaatcg cacgcgaaga tcgaaccgag gccgacgtga
     5521 tcagatcgat tctcagcaat cttgcattga gtccgccgac gcgtctgcgc tcccttgttc
     5581 cgtcacgcgg cgtcacgctc tccgacaaga cgatcgttct gacaggagct tcctcgggga
     5641 taggtgaggc gacagctcat ctcttggctc gtcggggagc cgagatgatc ctggtcgcgc
     5701 gcggtgagga aaacctcgaa cacgtacggg acgagattca ccgcagggga ggatgggcac
     5761 acatcgtgcc tgcggacctc tcccgcggtg aagccgtcga cgaactcgcg gagacgatcg
     5821 cggatcgatt cgggtcggtc gatatcctcg tcaacaatgc gggtcgctcg atccggcgta
     5881 ccgcgttgga ttcggtcgac cgattccacg actacgagcg caccatggcg ctgaactact
     5941 tcgggccgac aagactgacg ttgcggctac tgcccgcgat gctcgaggcg aagtccggac
     6001 acatcatcaa cgtcggaacc tggggagtca ctgcgggcgt gatgcccagg ttcagcgcct
     6061 atcacgcgtc gaagtctgct ctcagtgcat tcggccgaag cctcggcgcg gaatgtcacg
     6121 gcaccggtgt cgatgtcacc acagtgcaat tcccactcat acgaacaccg atgatcgcgc
     6181 cgacggcgga ttacgtgagc cagccggcgc tgacggccga tcaagctgca tcgtggatct
     6241 tgagggcgat caatacgcgt cccgtcgagc tgtatccgcg gtacgcgggg ctgttacgag
     6301 cgattgacgt tgtatcccct tctgccactg acgctctcgt gcgaagggcc gggatctgag
     6361 gggttgggat ttgaggggtt gggatctgac cagaaacgtg caccagcacc ggggcatggt
     6421 tcgtccccgg tgctgatgta ttcgattgtc gcggttcacg ccgctgtggg tgggctgttc
     6481 ccgccgatcg gctgttgata cggatcgatc gacatcggtg gatagaacac cgtcttccga
     6541 tccggtccga tctcgacacg ccactcggtg tggtgcatcg tccggtggtg atgaccacac
     6601 aacagaacca ggttgtcgag atccgttggg ccaccatcgt tccagtgaac aatatgatgg
     6661 gcatcgcacc accccgacgg agtcccgcac cccggaaacg cgcacccgcc atcccggacg
     6721 gccagtgctc gcctttgcgg aaccgtcgct gttctcgctt ccttgccgca gtcgagcgga
     6781 acaccgttct catccaacaa aattcgcgtc acggtgcagt cgcacgccaa catccgcgcg
     6841 gtatcgatac tgatggggcc cacccaatcc gtccacgcga aacccagttc ctgagtcgac
     6901 ggcaagaggt ctttcaacgc ttgcaggtcc gtcatgtctt tcgccgacgc agtcaccgtg
     6961 atgtgcggtt tcaccccgcc ctcgatcgga cccaaccccg cccgctcgta ccgccgcaac
     7021 aattcgcaga acccgtccgc ccgtcgtaat gccggcgtac gggtgtcctt cacgccgtcc
     7081 ttctccggcg tcggagccga cagactcgac aacaacgtga tcaaccgggc cccgttgatc
     7141 gcatccagat cacccttcac agtgacccgc ccgtacaagc ctttcgaggc gtagaactcg
     7201 ttacgttcgg aatcctcgcc gaccgggacg ccgtcctcgc gcttgccgta ctgcttctcg
     7261 attcggcgga tcgctgcccg cactgcatca caatcggcga tgttctgcga cgccaggcca
     7321 agcaggatcc cgcgggcctt gtccacatcg gccggggtca tgttcttcgg tggatgctga
     7381 cagaacgacg cgacctgccg ggctttcaac gcatccacgt caccacggtg aaacgcatcg
     7441 cccacaacgg gttcgagcat caacaaccgc gccaacccga ccagcagact gcactcaccg
     7501 atctccagat tcgtcgaacc atgcaaccac tgcgcgatcg cccgaaaacc cttcccgccg
     7561 agaacctcac gggaaaacat ctccacgatc agcaacacca tccgcgactg caactcgtgc
     7621 cggacacgca ccagatccag aacctccccc ttgaggccct cgccatccag ctgccacgca
     7681 tcccgactgt ccatgccgaa agcataatcg aacagagttt cgaacacaag agaatgtgga
     7741 tcgaaaattg ctgctatcaa atcgatttcg acatttcgga cagtcggtta taggcgggtc
     7801 gccgacgaag tccacgtgcg ccgacgaatg cgagcgccac catcaacccg gagcacgaca
     7861 gcatcacggc agtctcgatg aactgaaatt gccagtaccg gctctgtggg tgatagatca
     7921 cggcatagtg atcgattccc tgttctcgaa ggcagttgtc gacctcgagg tcttgctgct
     7981 tgcgatcgga attgtctgag ccccagcaca ttgtgtaatc ggcgtcgatc atgttgccat
     8041 ccgtatcggc gaagccggca tcgatgaccc acctcgagtc gagattttca tacggcgacg
     8101 gtgcatattc cgctgcacgt gccagtccgt cgatgggttg cacttcagtg tcgggggcca
     8161 agtaatgctc gcgcatcgtc gcgctcagtg cgacgggcac gatcaagaac gcgagaagag
     8221 tcatgaccat cgcgaagacg gtgttgcgga tgagcaatgc ggctgcgctg ccggtagtca
     8281 ttgctaaaaa ggtgtaggcg ccgacgacga ttcccgtcgt ctgaaaattg gggaactcca
     8341 tcaaggaaaa cgaggtggcc tcatttgttg ccgcctgtcc ccggccaagc gtctgagtcc
     8401 agccgagcac caggcccagg actgccatcg caagggtgat gggaacgaag accaccagga
     8461 cccgcaagaa ataccatcga acaaggctgg tggactcgag aaaatcgagg ttttcgggac
     8521 cctgctcgaa gtctcgggcg aatgtggtga cgccgaccag cattcctgag gcgaacggta
     8581 gtaggagtac gagaagcgtc gtcaaggtga gagcggtgtc ggcacggcaa ctgccacctc
     8641 cgtcgtacca gcgtgagcag atgtcgccga agtcccaact ctcgcccgaa cgctgaacga
     8701 accagcctga aagtgcggct gtcaggatca ggaggaatat catcgccagt gaccatacga
     8761 tctgccctcg gcattgccgc caggtcgcgt agatcatcgg cgaatgcagc tcggtgaagt
     8821 gtggatgcgt tccatgatga aacgataccg ttcattctgt aatgggcctg ccacgcggaa
     8881 ccgccagatt tcgacatttt gtgtaggact taagtacgag ttcacctatg agtaaatcgt
     8941 ctaatatcct acttaaggtg ggatctttga aataaagcgc aaaaactggc acatgttcta
     9001 ggattttgtc tacggttaca tccacatcgt gatcgctcgg ccccagatcc cgcaatacgg
     9061 gcgacggata atagtaccga cgacatgcga atgtccgttg cgaaggagtg ggaaatgtta
     9121 gttccgttct tgcaggcgat tctgaatttc gcctacgggt caatcgatgc cggtggagtc
     9181 gtcatcgacg gactcgtcgg aatctcgagc gaataggagg atgtgagatg aattcatctg
     9241 atctgggttc ggtttcggcg ctcttgccca tgatgctgac tgctttcaag tccatcatca
     9301 caatgccttt cgcgctctcc gtggacttcg gcctcgacgt cccgttcaat ccgttcaaat
     9361 agattaggga gggcgaaaat gggttccttg gaagatgttt ttggtctttt caccgggtca
     9421 ctgtcagcga tccacgtcag cttcttcgag atgctgactg cattgtcgag cgacgggtgg
     9481 gtgcagggat gaccttccga tccggcaact cgcagcttaa ggaggtgagt atctgatgct
     9541 tttttctttc ttgagtaatg ctctgggttc gcttcgagat gtcagcggct tggcagtgat
     9601 gggaagcatg atgattccct cgttcagcgc ggaatgacat tgcaatacgg gtcgcttcgt
     9661 cgatagtcga cgcggcgacc cgtattttct tttcgatatg gattgtaaaa gccgataccc
     9721 cggacttgct ccgaggtatc ggcctgaggt cagaggcaga agaaactgag ggaactgatt
     9781 gccgcgttct gctcgagttg gccggcatct ccgacgttgc cggcggcgac tgacagatct
     9841 tgaagggaga gaatagcgtc cattgtcatt tcctttgttg atcggcgttc ttgccgatgg
     9901 atttgatcga tcgagtttgc ttgcggtgtt gatttaattc caggtttttc gcctggtact
     9961 tctgtgctcc aatctgccgt ggttgataac ttccgaacaa ttaggcgatg tggcagttcg
    10021 acgcgcacat cagtggaaac gactgtcggg cagttgccga tccggtatat cggagcaacg
    10081 ccagtattcc tgcagatccg gttgcccagt ctgttgagag tctcaggttc tgttcacctg
    10141 gaaagtgcag gcctcctgcg tgattgaggc tgtgcaagcc cagaagctga aactgctgtg
    10201 caagcgtctg ttcacaatcg gcgccggcgt atggagtctt ggagagttcg ctgagaaaca
    10261 gcatcagccc ggctcgcccg ttgagtagtc cggcttgggc agtgaattcg actgtggcgg
    10321 cccgggatat cgcacgcacc gcagctgcgt aacgcggttc gtcgacatgg cgcagaagtt
    10381 gtagaagtac caggcccaca ccgacagacc cggatccgag atacggcatc gtccggcgct
    10441 cctctctcag ctgcatcgac ccgtcagggc acatcgacat cacagacaga tcgatgtcga
    10501 cgagctggcg tgcgtgttcc agcgatcgag gatcaccact cagttcgtag tggcgagtcc
    10561 agaacagtgc ttgtccgctc ggtccccgca tcagcccacc tcggccggcc actgcccaag
    10621 gtgttccgcc ggcgtcgcgg acatgcaagc gagcagctga aattcgttcg cgcagagtct
    10681 cggtcacgac agcgagagtg ggtgacacag tcggtcgtga aaccgattcc tcgagtagga
    10741 ggcaaccgat tccggaaagg ccgctgaaaa ggctggagtc gatgtcgtcg agtggggctc
    10801 gacgcaaagt ctcgacccac ctgtcggctg tcgaatgtcg cccgtgatgc cgaaaggtat
    10861 gcaccgcacc cgcgagcccg tcgaagaagc cgaactttgg ttgagtatcc gaatcaactt
    10921 gatgttcagt ccattccaga actgactcca aggtgtctgc gggaagtaca tcggcgagca
    10981 ggtttccgca cgagccgtga gcaatgccgt agccgttcac ctcgaactgg gcgatgtcgc
    11041 cgggaaagag tcgatcagcg cgggcgagat caagcgaggc gaggatgccg cagcgcaata
    11101 gagcggccgt gcgttgcaag gtttcgttcg acgacgtgtc ccaacgatgc gggcgattct
    11161 tcggcgccgg cgcctgtacg tcgagcatcg aatagagcga ggcaccgaag gcgcggggaa
    11221 gatcgaatcg agacaccgca tagtcgatga gttcgggaat cttgttgcga tcgagaggga
    11281 acaatgtagt aagtggaaca aagagtccca gctcgatgca gcccaacgag tatcgatccg
    11341 ccgcgattcc tgtcaactgt cgaggtgctg tgtatccggg ggctccggtg gaccggggcg
    11401 gatgctcgtc gatgttgtgg gccatctcga agtcgatgat ccgaataccg gacggtgagc
    11461 acatgacgtt gccagggtga agatcggcat gaacgattcc ggcgttgtgg aagctctcga
    11521 ctgcggtagt caactgttgt gcaatgtcga gtgcccaggt tctgtattcc gttcgggaac
    11581 tgagtgtctg gtccgcgcgt atcagtgggt ggcggagcgc aacttcctga ttcaggggag
    11641 tgccggcagc gcgctcggtg acaaggaagt ggtgtccctc gcgctcgaac aacctgatcg
    11701 cagaaggtgc gtacgggttg tcggcaaggt gggtcaactt gtcgtactcg ttacggatgc
    11761 ggtcgattgc gtaccggccg ttggcgtccg gggcggtaaa gggacggcct tctttgatga
    11821 ccagatcgat gccggcgtcg tcgaacgcgg agtagatccc cccgctgttg ctgaagtgca
    11881 gggcttcatt gatcgaatag gggaattcgt catgtgattt cagcttgtct tgctgcgcgc
    11941 gaacgaagtc cgggatttgt acccagtccg gagttctgaa ggaagtgccg cgcacatcgg
    12001 gttcgagcga tccgtcagga cgccgaattg cggggacgcg atcgccgaat gaatcgtagg
    12061 tctgcatggg cagatacgcg ccgtaccgta agtagagcgg tccccggttc catcgcacat
    12121 cgctgaggat gtacggcccg tcggcaccgg tgacaagctt gtccagttcg gtgatgacac
    12181 gttgtgtggc aacaccatcc gccggataga tcgtgatgaa ttttccgctg gaagttcgat
    12241 tggcctgctt gctgttggac aacatcaggt ctgctgccgt ccgaagaaat ttgaacggca
    12301 catgattgtg accgcaatac acggaaacgg tatcgagcag ctcctgcgcg ttggcttggg
    12361 tagcggagca gtgaatcttc catccttgtt ctggcagcag accgtcgggc ggttggaagt
    12421 agttccacgg tccactttgg ggaccgcgcc gccagagcga ccaatccacc gacttcgcgg
    12481 ggataaagtg ctggtcagtt gatgtatctg gtcgggtgac cgttctgatt cggtcgtaga
    12541 aatgcgggtc ggcacgcgtg aaggcaacgt atcgcaggtc cacgccaaac ctcccggtca
    12601 gtccccctgc ggttgtcatc gattggtgcc acgccccgaa tcccctgtgg cttggattgc
    12661 ttgtggcgga aggttatccg attccggaca tttcgggcga agattgaaaa cctatcattc
    12721 gaaagtacta atgaagggtg tgggccaggc gaggtcactg atcgcttagc ttttagtcgg
    12781 ccgcatttgt ttcgagttcg gaggccccct cttgacgaga ggatcaagtc ggtggtagtt
    12841 ctttagcgag cgctaagtca gggtgctccc tcgatctcgg tccggtaccc ggcgccacga
    12901 aacacgggtg ccggaccgcc ccagcaatgc acgtcctcga agggaacgaa gatgaccaag
    12961 gcagtgatcg tcgatgtagt ccggatcgcg tccggcaagg gaaagccggg cggagcactg
    13021 tccgggacgc accctgtcga actgatggcc cacgttctgc gttccatcac ctcgcgaaac
    13081 ggcctcgacc ccgccctggt ggacgacgtg atcggcggtt gcgtcggcca ggccggtgag
    13141 caggcgctca acatcacccg cagcgcggtc ctgtcggcag ggttccccga gtcggtaccc
    13201 gccaccacga ttgatcgcca gtgcggatca agtcagcaag ctgcgcactt tgcggcgcag
    13261 ggcgtgatcg ccggggccta cgacatcgtg atcgcggcag gcgtcgaatc catgagtcgt
    13321 gtcccgatgg gtaccacgac gatggggaag gacgcttccg gtccgggcgt cgcggctcgc
    13381 taccccgaag gcctggtcaa ccagggaatc tctgcagaat tgatcgccgc caagtggaag
    13441 cttgaccgcg acgctctcga cgcattctcc gcgcagtccc accagcgggc agcagaggca
    13501 gcggcgaagg ggctcttcga caaggagatt ctgccgatct cggtgaccaa cgccgccggt
    13561 gagaccgtct cgcatatcgt cgacgagacg gttcgcgcgt ctactaccgc cgagggactc
    13621 gccggtttga agccgtcgtt ctactcggag aagtacgcgc agcgcttccc cgaggcgcag
    13681 tggtcgatca ctcccggtaa ctcgtcgccg ctcaccgacg gcgcgtccgc agcactgatc
    13741 atgagcgaag aaatggcgtc gaagctaggg ctgacgccgc gagctcgttt ccattccttc
    13801 tccgttgcgg gcgatgaccc gatcttcatg ctcaccgcac ccatcccagc cacccacaag
    13861 gtgctcgctc gcgcgggtct gagcatcgac gacatcgaca cctacgaggt caacgaggca
    13921 tttgctcccg ttccactcgc ctgggctcac gagttcggcg ccgacccggc aaagctcaac
    13981 ccgtggggcg gcgcgattgc actcggccat gccctggggt cctcgggtac tcgtctgctg
    14041 accacgatgg tcaaccacct cgaggccacc ggcggacgct acggattgca gaccatgtgc
    14101 gagggcgccg gcatggccaa cgccacaatc atcgaacgca tctgaaacac ataacctttc
    14161 gaaaggaact ctcatgatcg tcaacgacag cgtcgccgtc gtcaccggtg gagcatccgg
    14221 cctcggcctg gctacgacca aagcccttct tgccgacggt gccagcgtcg tcattatcga
    14281 ccttccgtcg tccaacggtg aagccatcgc caaggaactt ggcgaccggg tccgcttcgc
    14341 ggctgcagac gtcaccgacg aggctgcggt caccgcggca ctcgacgtgg ccgagtccct
    14401 cggacccctg cgcgtggcag tcaactgcgc cggaatcggc aacgcagtca agacggtcag
    14461 caagaagggc gctttcccgc tcgacgcgtt caagaaggtc atcgacgtca atctgatcgg
    14521 caccttcaac gtccttcgtc ttgctgcgga acgtatttcg aagaccgagc cgatcgacgg
    14581 tgaacgcggc gtcatcatca acaccgcttc ggtcgcagcg tatgacggcc agatcgggca
    14641 ggctgcgtac tccgcgtcga agggcggcgt cgtcggtatg acgcttccca tcgcccgtga
    14701 cctcgcgtcg ctgctgatcc gcgtcaacac cattgcaccc ggcttgttca agaccccgtt
    14761 gctggctgga ctgcccgaag cagcccaggc gtcgttgggt cagcaggtgc ctcacccctc
    14821 tcgcctgggt gatcccagcg agtacggcgc gcttgctgcg cacatcgttt ccaaccccat
    14881 gctcaatggt gagacgatcc gcctcgacgg tgcaatccgt atggcaccgc ggtaatttcg
    14941 gctatcacat gactggcgag gtggagtcgg tgagctcggt ggcagtggac tggaggtcct
    15001 tcccgccgct ggtgatgacc gacatcctga cggcttcgct cgaactgttc gacgagaacg
    15061 gttaccacgg cacgacggtg cgccagattg ccaatcgtgt cggggtaacc gttcccgcgc
    15121 tctactatca ccacgcgaac aaagaggcag ttctcgtcgc tttgttcgag gtctcgatga
    15181 gtgagctgaa taccagaacc gaagcggcag aagcggaggc cggcgaaaat ccggtacgac
    15241 gcttcgcctt ggtggtggag gcgattgttc tctatatgac ccaccggtcg cggcatgctg
    15301 cgttggacac cgagatccgg catgtctcac cggaaagtcg aagtcggtac gccgccagtc
    15361 gtaagcggct cgagttgctg atgcgcagga tcgtcgacga cggtgtggca tcgggagatt
    15421 tcgcggtcac cgataccgaa gagaccgtcc gggcaatact cggtatggcg cagtcactgc
    15481 cgcgttggtt ccagaccggc ggtccgatgt cgccgtcgca gttggcgcag aagtacgtcg
    15541 acatcgcttt tcacacggtc ggctatcggc cgtaaagtgc ctcgctcgtg aacgaaggtg
    15601 ggcaacaggt cgaaaacctg ttgcccacct tgagtattca gacttcgaca ttcactccgt
    15661 gtcagagtcg cgtaacttcg agtccgccct cgtggtagtc ggcgcgaagg cgtttcttgt
    15721 cgaacttgcc gacgctcgtc ttcgggactt cctgaaccac ggcccagttc tcgggcagct
    15781 gccacttggc aaccttgtcc gaaaggtact gttgcagttc ggacatggtg gtttcggaac
    15841 cggcgcgaag gacaaccgca accaacgggc gctcgtccca cttctcgtcc ggcacgccga
    15901 tgacggcagc ttcggtgacg tcggggtgac ccatgacggc gttctcgagg tcgaccgagg
    15961 agatccattc gccgccggac ttgatgatgt ccttggagcg gtcggacagg ctcaggaagc
    16021 cgtcggccgt gatggatccg acgtcgccgg tcttgagcca gccgtcgttg aacttgtctt
    16081 ccgcgtcgac gccgtagtac gacccggtga tccaagggcc gcgcacttcg agttcgccga
    16141 cggaaactcc gtcgtgtgca acaactttgc cgtcgtcgtc gatgagacga gcctcgacgg
    16201 atgccgggaa tcgaccctgc gagtagcggt acttccacat cgcgtcgccg gtgacaccgg
    16261 ccggcggacg ggcaacggat ccgagcgggg aggtttcggt catgccccag gcgtgcagga
    16321 cggagacgtt gtgatcggct tcgaatgcgt gcatgagggc gggcggtacc gcggagccgc
    16381 cgatcagaac ctcacgcatc gaggagatgt cctgcgggtt ctgctcgagg tagaggtgca
    16441 ggccctgcca gatggtgggt acggccgcgg cgaacgtcgg ctgctcgctg gcgatgatcg
    16501 cagccaacgg ggcaggctgg aggaagcggt cgggcatgat cagcgaggcg ccgatcatga
    16561 acgcggcgta gggaagtccc cacgacatgg cgtggaactg aggcaccacg gcgagcgcac
    16621 gatcgccctg ggcgaggttg gggccgtcgc tcatgcagac ctgcatggag tgcaggtaga
    16681 tcgaacggtg ggagtagacg acgcccttgg ggtcacccgt ggtgccggac gtgtaacaca
    16741 ttgcggcagc gctcagttcg tcgacctcgg gccagtcgaa ctcggtgggc tgatcggcga
    16801 tcaagccctc gtaggtgtga acctgcactc cctcgggagc ttcgagtcct gcagtggagg
    16861 agccggtgac gacgatgtgt ttgacggtgg tcagcgacgg aagctgcgga gagagaagcg
    16921 gaatcaggga cgggtcgacg atgatcacgc ggtcctcggc gtgattggcg acatggatca
    16981 actgctcggg gaacagacga atgttcaggg tgtggagcac agcgcccatc gaggggatcg
    17041 ccaggtacgc ctcgaggtgc tcggagttgt tccacatgaa cgtggcgact cgctcgtcgc
    17101 cctcgacgcc gagcccgcgc agggcgtgcg cgagctgagc acagcgcttg ccgacgtcag
    17161 cgtaggacac acggcgcggg ccggactcgg tccacgtgac aacctcggag gcgccgtgaa
    17221 cggaggcacc gtggcggaga agttgagcaa tggagagggg ggcgtcttgc atggtgctca
    17281 gcatgggctg ctcctgtgtg gtgtgtgaga ccggtgcttt tgcccacggg tcgtcacaaa
    17341 cgatgtgctg tggctgccag attagtcaca gccccgaagt gctcgctagt gacccactgc
    17401 actggcgaag aaccacgcta tgagtagcgc tcccggatcg actactccgc gagcggcttc
    17461 gcccacataa cttgcacgtc cgcggttcgc gagcatggtt tcggtcgact ccgccccggc
    17521 cgctgcggct tccgctgcgc tcgccagcgc agcatctcga tcggcttccg agctcacgga
    17581 ttgctccaac gactcgaccg ccggaactat cgcgtcgacc atcgtcttgt cgccgacgcg
    17641 tgcgccgccg agcgaggtga tgttgtcgag tcccgctcgc gctgcagccg cgatcgcgcc
    17701 gaggtcgagt tcggagtccg ccgagtctgc ggcaacgcgg aagaaatgcc ggaaccagat
    17761 gccgaacaat gcgccggagg tgccaccggc gtggccgagg tacgcctgtg agactgcatc
    17821 gaatatcgtt gcggtggagt acgtgtcacg gatcgccgag atgtcgagtt gatccagtgc
    17881 ggccaccatg ttggtcccga aatcgccgtc gcccgctcgt cggtcgagat cggtcagtgc
    17941 cggttcctga tccagtacct tctcggccca gtccgcaatc cagcttccga cgaagctgct
    18001 ttcggcggtg cgtgaggtgt cgggtgtgaa tgtgggaccg aaagattcgc gcgtgcccat
    18061 gccggtgtac tcacgcgcta tagcattcgg ccaggcgggc gcttttgttg gtgcgtccca
    18121 taattcgagg atttctttgt ctgtgcgaac aagggtgatg gacgcgcctg ccatgttcaa
    18181 tgcagtgacg aaggctccga tcagtgtccg ctcgatgtga attccctgtt cgtccagata
    18241 atctccgagt tcggcgaaca gaagttgcaa ctccagcggg tgggtggcgc cgagaccgtt
    18301 gacgacggcg atgacgcggt cgccttcggc gagactcagg gacttgatga tcgggtccgt
    18361 cagccgccgc accaattccg gtgcgggcag ggcgtccacg cgttctgtgc cgcgttcgcc
    18421 gtggatgccg ataccgagtt ccatctgacc cgccggcaag tcgaacgacg gctcgtcagc
    18481 ccccggcaaa gtgcatgggc gaagggcgac ggccatgctc cgagcggagt gcgcgacgtg
    18541 ttgtccgatc cgggtcacct cggccaggtc gtcgccgcgg gcggcggatg cgccgcagac
    18601 cttctccacc acgatggttg ccgcagtacc gcgtcgtccc ggaccgctgc cgtctgcgcg
    18661 ttcggtcgcg acgtcgtcgt cgaccaggac gacgtccgta tcgatcttgt cctcgcgtag
    18721 caactctcgg gcgataccga agttcatcac gtcgccggtg tagttcttca cgatgtgaag
    18781 gacgccgccg ccggcgtcgg cagccttgga tccctcgtgg atctgaagtg cattgggtga
    18841 gctgaagacc aatccggggc agacggctgt gagcattcct tcgccgatga atccggcgtg
    18901 catgggttcg tggcctgaac cgccgccgga gacgagcgcg acccgtccgc ggggaagtgg
    18961 ccttgcgcgt gtgaggtacc cagggtcggg attccacgcg atgtcgtcgg tggatgcgat
    19021 caacccacgg agtgcgtcgg gaacaaatgt ctttgcgctg cgcatgaaca tcacttcaga
    19081 gtaggtctaa cgtcgacttc gggcacggat cacgatcgac gagaggtgga cggcgtgaaa
    19141 ttggggttgg tacttgccgg tggcggcgtt gcgggaatcg cctgggaaac aggttttctg
    19201 ttgggccttc aggacaaatc accggacact gccgctgcgc tgctgacggc ggacgtgttg
    19261 atcggcactt ccgcaggttc cacggtgagc gctcagatag cgagcggcgt gacactgcaa
    19321 gaacttttcg acgcacaaac agcggaggcg accggcgaaa tcgacccgaa ggtcgatgtc
    19381 gaggtactcg gtcagatgtt cgtcgacgcg atcgcaggat cgcaggaccg ggccgagcag
    19441 ctccgttttc tcggcgaagc agcgatgaga gccgataccg tcgaacctgc cgtgcgtcgc
    19501 gcggtcatcg aggcgaggct gcccaatcgg ttgtggcccg accgggagtt gcgcatcccg
    19561 gcgatcaacg cacagaccgg tgagttgagg gtgttcggca acgctgacgg cgtagaactg
    19621 atcgacgcag tcggagcaag ttgcgccgta ccaggggtgt ggccggtagt cgtgatcgag
    19681 ggcgagcggt acatggacgg cggaatggcg agtggctcga atgttcatct ggctgccgac
    19741 tgcgatgtgg tcgtggttct ttcacccgca gccgaccccg ccccgaatct tctgggcggc
    19801 agtctacgag aggaaatcga cgtgatgacg cccttgcccg tgctgcctgt cttcgccgat
    19861 tacgccgtcg tcgaagcgat cggaacgaac tcgctttcac cgacaaccag gcgccccgca
    19921 gccgaactcg gccgcgaaca gggccgtcga accgccgacg agatcgccgc gtttctggtg
    19981 acggcatgag cgccgcacgg attgccgtcg tcgtgcgccc ggagcaatct ccggaagatc
    20041 tggttcgaca tgccaggtat gcagacgaag tcggtatcga cgaggtctgg ttgtgggaag
    20101 actgcttctt cggcggagga atagccactg ctgcaactgt attggctgag accgatcgcg
    20161 tgggtgtggc gatcggtgtg ctgccgaccc cgatgcgcaa caccgcgatc acggcgatgg
    20221 agatttcagc gctggccaga gttcatccgg atcgactacg ggttggcttc ggtcacggcg
    20281 ttcagagttg gatgcggcag atcggggcca aagccgaatc gccgttgacc ctcctgcggg
    20341 agcagttcgg agcagtcgag cggctactgg gcggtgagtc ggtgacggtg tccggtcgat
    20401 acgtgaatct cacggacgtc acgctggcgt ggccaccgga gacggtgccg cagttgctcg
    20461 tcggcgccac ggggccaaag actttggcgc tcagtggcga gttggcgcag ggcaccgtgc
    20521 tctcgggtgg gacgaccccg gacggcgtgc gtcgggcgat cgctcacatc ggggcgtcgg
    20581 atcacgaggt cgtcgtctac gtcatctgtg ctttcggttc cggcggtcgt gagcgcgccc
    20641 ttgccgaggc cgcagcgtcc gatagcgagt cgccggagga tgcgattgcc gtgggcaacg
    20701 cggccgaagt cgcggcagca acacggcgat gggttgcagc aggtgcaacc accgtggtac
    20761 tccaaccgac tgttgacgag ccggatgtcc gcgagttcat tcgctttgtc gcgcaggagg
    20821 ttcaacccct ggtggcgtag ttcagaaggt tactctggac agaaccgcgt cgatgtcggc
    20881 agtgctcacg tcgcgatgtg tcacgaaccg aaccttcccg gcaacggtga ccgccccgac
    20941 atcgacagcg gcgagctgag caacggtgac cgacggatcg gctgtcgcgg ccagaacgat
    21001 gttggtggca ggttcgtcga cggcccaacc gcgttcacga agccccgacg cgaggcgctg
    21061 cgcgttgtcg tgatcgtcgg agaggcgagc ttgtgagcgc aacgcgacga tgccggctgc
    21121 ggccagcact ccgccctgac gaacgccgcc gccgagcatc ttgcggatcc ttcgggcttc
    21181 ggtgatcaat tcgggtgatg cggcgagtat cgagccgacc ggcgcaccga gtcccttact
    21241 caggcacacc tgaacggtat cggcgccgga agtcaattcg gtgggcgaaa catcgagtgc
    21301 agcagcggca ttccagagac gggcgccgtc gaggtgaatc ttcaagccgc gtgatcgcgc
    21361 tgcgtcgacc agcttcgtcc attcggtcgg attcatgacg gcaccgccgg cgaagttatg
    21421 agtgttctcg agacagagca gcgtggtgtt caacgcgaag tacgggccgg gggagcccgc
    21481 cgccttcacg acagtctcgg gggtgggacg tccgggtccg ccgtcgtgcg gcaacgccat
    21541 cggcattccc tgggcgagcc aggcagcggt gcccaattcg gagcccaaga cgtgagagtg
    21601 ttccggtgcc agaaactgat cgccgcggtg aaggtgcagc atcagcgcaa tcaggttgcc
    21661 catcgatccg ctcggcaccc acagtgccgc cggtaaaccc agagtgtgcg ccacctcttc
    21721 ctcgagcgcc gccatggtcg ggtcgtgatc gaggacgtcg tcaccgacct cggcgtcggc
    21781 catcgccttc cgcatctccg catcaggctt ggtgacggtg tccgagcgta ggtcgatgta
    21841 cgacgaagtc atggctcatt cgatcaagcc gcgtgttccg gcgtcaaacc gcggtatttc
    21901 caggacggct cttccggcct gataaatcga tatcgctgag gatgccttcc gtgtgatgat
    21961 gagcgccggc aatcgccggt gacgagaaca agaagtggaa ggggacaggc atgcgcgact
    22021 ggaagcaagc gttgcacctg cgcgggcact caccccgcgg tatttcccat cccgcattcg
    22081 gggaacagag cggcgctgga tatatgccgt tccccatttc ttgcatttgc tcctgacccg
    22141 tcttcgtgtc caggagtttc actcctcgac acgaactgag aactctcatg cggaacccga
    22201 accgcgcact tgctcacagt tggatgaacc gccccgtccg ggtactcaac gccacgtacg
    22261 agtacctcgg tgaagtgagc gccgatcgtg cggtcgtcct gatcgccacc ggctccgcgc
    22321 agtccaccga ggacgtgacc ccgatatttc cggtgcgctc caagcacgtc gaaatcccac
    22381 tgccgaggac gatcctgctc gccgagtacg tgtacgttgc tcaccgggtg acggtcaccg
    22441 attccagtcg ggccactttt gccggtgtct tcgaccggga cggtcgtcaa tgtgcgtact
    22501 gcgccgcccg ggcaacgacc atcgaccacg tccagccgcg gagccgtaac gggcccaaca
    22561 cgtggggaaa tctggtggcg tgc
//
