LOCUS       NZ_JAJNDF010000002     25366 bp    DNA     linear   CON 29-AUG-2024
DEFINITION  Rhodococcus qingshengii strain IEGM 746
            NODE_2_length_767368_cov_137.515908, whole genome shotgun sequence.
ACCESSION   NZ_JAJNDF010000002
VERSION     NZ_JAJNDF010000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Rhodococcus qingshengii
  ORGANISM  Rhodococcus qingshengii
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Rhodococcus; Rhodococcus erythropolis group.
REFERENCE   1  (bases 1 to 767368)
  AUTHORS   Elkin,A.
  TITLE     Development of a sustainable strategy for remediation of
            hydrocarbon-contaminated territories based on the waste exchange
            concept
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 767368)
  AUTHORS   Elkin,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-NOV-2021) LAM, Institute of Ecology and Genetics of
            Microorganisms, Ural Branch of the Russian Academy of Sciences,
            Golev Str., 13, Perm, Perm Kray 614081, Russia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 16-NOV-2021
            Assembly Method                   :: SPAdes v. 3.14.1
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 275x
            Sequencing Technology             :: Illumina NovaSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_021026075.1-RS_2024_08_29
            Annotation Date                   :: 08/29/2024 04:42:17
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,393
            CDSs (total)                      :: 6,335
            Genes (coding)                    :: 6,273
            CDSs (with protein)               :: 6,273
            Genes (RNA)                       :: 58
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 62
            CDSs (without protein)            :: 62
            Pseudo Genes (ambiguous residues) :: 0 of 62
            Pseudo Genes (frameshifted)       :: 21 of 62
            Pseudo Genes (incomplete)         :: 52 of 62
            Pseudo Genes (internal stop)      :: 5 of 62
            Pseudo Genes (multiple problems)  :: 14 of 62
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:48:56
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 294474
            Orig. end                         :: 319840
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            JAJNDF010000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25366
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..25366
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25366
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:15366](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15366
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    466..480
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.69"
                     /tool="antismash"
     gene            complement(1474..2118)
                     /locus_tag="LQ424_RS05910"
                     /old_locus_tag="LQ424_05905"
     CDS             complement(1474..2118)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748878.1"
                     /locus_tag="LQ424_RS05910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05905"
                     /product="hypothetical protein"
                     /protein_id="WP_003941715.1"
                     /transl_table=11
                     /translation="MSRQGKSGAAQRAYDKRTARAAGRTGTVAAAGPSISPRAMLKGRV
                     PFVASVIGLLSIGLAVTLLLTTRAAEDSYQLSDARAYNQSLVEQKAALERDFQSRNSAP
                     ELANQASALGMVPAKDPARLVVHPDGSVEVVGTPTPATAGAMPPLDAPTSVPAPTATPP
                     RTTTPVAPGATPSVPNNTRNLAQSEQLVPVIPTTTAPATTTAVPAPPEERR"
     gene            complement(2115..3128)
                     /gene="rsmH"
                     /locus_tag="LQ424_RS05915"
                     /old_locus_tag="LQ424_05910"
     CDS             complement(2115..3128)
                     /EC_number="2.1.1.199"
                     /GO_function="GO:0016434 - rRNA (cytosine)
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene="rsmH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730079.1"
                     /locus_tag="LQ424_RS05915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05910"
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="WP_007730079.1"
                     /transl_table=11
                     /translation="MVDHEVNEPSDADGFAHVPVLLHRADDLLGPAITAVGDGGAGAYM
                     IDATLGLGGHSEFFLGKYPGLHLIGLDRDTNALRIASERLAPFADRTTFVHTTYDGIED
                     ALEQAGLPSTESVHAILFDLGVSSMQLDEADRGFAYSIDAPLDMRMDQTVGLTAAEVLN
                     TYSHGDLARILSTYGEERFAGKIASEILRQREREPFTTSAALVELLYRTIPAATRRTGG
                     HPAKRTFQALRIEVNAELDSLRAAVPAGLDALAVGGRVVFMSYQSLEDRVVKAELVPRS
                     KSTSPEGLPVELPGMGPEFRILTRGAERASEQEIEENPRSAPVRLRAAERISRRRA"
     gene            complement(3319..3750)
                     /gene="mraZ"
                     /locus_tag="LQ424_RS05920"
                     /old_locus_tag="LQ424_05915"
     CDS             complement(3319..3750)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="mraZ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011560648.1"
                     /locus_tag="LQ424_RS05920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05915"
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="WP_003941779.1"
                     /transl_table=11
                     /translation="MFLGTFTPKLDDKGRLTLPAKFRDELAGGLMITKSQDHSLAIYPR
                     DEFVKLARKAAAAPRNDPAARAYVRALAAGTDEQHADAQGRITLSADHRRYANLSKECV
                     VTGSVDYLEIWDLAAWERYLGDNEEDYSQATGESLSEIV"
     misc_feature    complement(3878..3892)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.88"
                     /tool="antismash"
     gene            4154..4348
                     /locus_tag="LQ424_RS05925"
                     /old_locus_tag="LQ424_05920"
     CDS             4154..4348
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941749.1"
                     /locus_tag="LQ424_RS05925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05920"
                     /product="hypothetical protein"
                     /protein_id="WP_003941749.1"
                     /transl_table=11
                     /translation="MIRSHVTDSLDGLPAHTYNTHSNGVWRSATLVADRHTCGRPCPEE
                     GVTSELHHSRSTPEEGRES"
     gene            complement(4345..4791)
                     /locus_tag="LQ424_RS05930"
                     /old_locus_tag="LQ424_05925"
     CDS             complement(4345..4791)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941660.1"
                     /locus_tag="LQ424_RS05930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05925"
                     /product="DUF3040 domain-containing protein"
                     /protein_id="WP_003941660.1"
                     /transl_table=11
                     /translation="MPLSEHEQRMLDQIESALYAEDPKFASNVRGGRMRAPSSRRRFQA
                     AALFVLGLVLLIAGVALPLKPGGFPIISLFGFLFMFGAGVLFLWGGGRKSAPAADSASE
                     GGNHPSGPPGRGSAGGSGRGRGRKSGGGFSSRMEDRFKRRFEQD"
     gene            complement(5029..5580)
                     /locus_tag="LQ424_RS05935"
                     /old_locus_tag="LQ424_05930"
     CDS             complement(5029..5580)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748881.1"
                     /locus_tag="LQ424_RS05935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05930"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_223304500.1"
                     /transl_table=11
                     /translation="MSERVKPERVKCQRTLPAELSSPSDAAISRLPMSARRSFGARDAS
                     DRTARVGKSGVAWGLLRKADALLEEAIGAGDPADRFRCAYLAALRGAGAVLAAAPAGAG
                     SKRKRSGNAWVLMDAAAPAFGAWSKFFAGWSSTRAAVETGVSIVITDSDSDAFFAEVGR
                     FLTAVEDFIGQDASEHLRAS"
     misc_feature    5666..5681
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.27"
                     /tool="antismash"
     misc_feature    complement(5667..5680)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.07"
                     /tool="antismash"
     gene            5728..6333
                     /locus_tag="LQ424_RS05940"
                     /old_locus_tag="LQ424_05935"
     CDS             5728..6333
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748882.1"
                     /locus_tag="LQ424_RS05940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05935"
                     /product="N-acetyltransferase"
                     /protein_id="WP_042452829.1"
                     /transl_table=11
                     /translation="MRPVDPQIAWTPHTVDLDRAEFASRLHEALAVYVTAMDYPRGTEF
                     HRAPMWQEHANRPGWKAVGALAVPQQPSHENLPLVGIAYGYRGSPDQWWHQQVLHGLRR
                     SGRPQSEIDAILSDYFELTELHVHPNGQGHRLGESLLRHLLVDRPERSVLLSTPEVYDE
                     DNRAWRLYRRLGFCDVLRRFRFAGDNRPFAVLGRGLPL"
     gene            6330..7928
                     /locus_tag="LQ424_RS05945"
                     /old_locus_tag="LQ424_05940"
     CDS             6330..7928
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748883.1"
                     /locus_tag="LQ424_RS05945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05940"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_042452826.1"
                     /transl_table=11
                     /translation="MSALLDAVVVGSGHNALVSAAYLAREGWSVEVLEKDTVLGGAVST
                     VERFPGYKVDRGSSAHLMIRHSGIIEELGLGAHGLRYIDCDPWAFAPPAPGTDGPGIVF
                     HRDLDATCWSIERACGTKDADSYRRFVAVWSERSRHVMKAFSAPPTGSNLIGAFGGLAT
                     ARGNSELSRQFLAPGDALLDEYFDSEALKAALAWFGAQSGPAMSEPGTAPMVGFAALMH
                     VLPPGRAVGGSGALSAALASRMAVDGATVALGDGVTSIRRNSSHWTATTESGREVHARK
                     VIAGCHILTTLDLLGRGGFDRTTLDHWRRKIRVGPGIGAVLRLATSALPSYRGDATTRE
                     STSGLQLLVSDRAHLRTAHGAALAGELPPRPAVLGMSFSGIDPTIAPAGRHQVTLWSQW
                     QPYRLSGHRDWASVAEAEADRIVGEMEAFAPGFADSVLDRFIQTPRDIESELGMIGGNV
                     MHVEMSLDQMMLWRPLPELSGHRVPGADGLYLTGASTHPGGGVSGASGRSAARIALSDS
                     RRGATRRWMRRSSRS"
     gene            7999..8793
                     /locus_tag="LQ424_RS05950"
                     /old_locus_tag="LQ424_05945"
     CDS             7999..8793
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941798.1"
                     /locus_tag="LQ424_RS05950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05945"
                     /product="hypothetical protein"
                     /protein_id="WP_063892119.1"
                     /transl_table=11
                     /translation="MTTVQQSTDPAAKPTSRKRFLTVAALALMLVPLLAGCIRVQVSMG
                     VSANDRVTGQVVAAAIPANEADKGPQLTPPSSLEDKIRVQEYKKDGYVGSQAFFSDLSF
                     GDVAQLGSMYAEGSGSFQITLKRSGDTVTLDGKADLKTVPTQGADVQVSIAFPARVGTT
                     NGTRDGDSRVSWTLPAGEVSTMRAEVNYADPSTRSFAGWAGIMAGLALGVAIVVGAMAW
                     MARNRAPIKRAPAAKAPVMKTPVTKSPASKQADNRNPKNTTK"
     misc_feature    complement(8048..8059)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.3"
                     /tool="antismash"
     gene            complement(8841..9830)
                     /locus_tag="LQ424_RS05955"
                     /old_locus_tag="LQ424_05950"
     CDS             complement(8841..9830)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941803.1"
                     /locus_tag="LQ424_RS05955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05950"
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="WP_003941803.1"
                     /transl_table=11
                     /translation="MTFDPVRGRSSEGWATRTPSIVDRIASSTGSRIPFSVEFSPPRDA
                     DAEARLWRAVRTFERLGPAFVSMTYGAGGSTRDRTVRVTGELAEETTLLPVAHLTAVSH
                     STEELRAMVGAYADRGISNILVLRGDPPGDPLGEWKKHPEGVEYAEELVRMVRDLGDFH
                     VGVASFPEGHYRAPDLAYDTKYLVSKLRAGAEYSITQMFFDVEDYLRLRDRVSAYDAEQ
                     GAKPIIPEIMPVTSLRSVRRMLELSGSSLPPALERRFDAAAGSGPDENRAAVRELGIDL
                     ATEMGERLIAEGAPCLHFITLNFARATSEVLERLGLTPDTSVGTAQAV"
     gene            10001..11140
                     /locus_tag="LQ424_RS05960"
                     /old_locus_tag="LQ424_05955"
     CDS             10001..11140
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748885.1"
                     /locus_tag="LQ424_RS05960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05955"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_080726734.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.6e-49, bitscore:
                     162.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEATLSAGTARVGQSSTNTAPHPTSLELPGLFEAALRDFFASRRE
                     LVSNIGGGYEEAVSTLEAFVLRGGKRVRPSFAWTGWLGAGGDPNGKGADAVIRACAALE
                     LVQACALVHDDIIDASTTRRGFPTVHVEFEDQHRDEEWSGDSAHFGEAVAILLGDLALA
                     WADDMIRESGISPEAAARVSPVWSAMRTEVLGGQFLDISNEARGDETVEAAMRVNRYKT
                     AAYTIERPLHLGAALFGADAELVDAYRTFGTDIGIAFQLRDDLLGVFGDPSVTGKPSGD
                     DLIAGKRTVLFAMALARADAADPAAAELLRNGIGTQLTDTEVDTLRQVITDLGAVTDVE
                     TQIDTLVEAAANALDSSTATAESKARLTDMAIAATKRSY"
     gene            11143..12735
                     /gene="crtI"
                     /locus_tag="LQ424_RS05965"
                     /old_locus_tag="LQ424_05960"
     CDS             11143..12735
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941668.1"
                     /locus_tag="LQ424_RS05965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05960"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_230793119.1"
                     /sec_met_domain="DAO (E-value: 3.6e-12, bitscore: 41.8,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHVHRTRTVSSPTDRVVIVGAGLAGLSAGLYLRGAGRDVTILES
                     NSSVGGRVGVYQGNDYSIDNGATVLTMPELVEDALAAVGADPASTNPKFVVHKLDPTYH
                     ARFADGTALDVHADPEDMAAEVSRVCGPEEAQRYRALRRWLNRIFDAEFDRFMDADFDS
                     PLGLVNSRDAVKDLSRLVALGGFGKLGGQVDRKIRDPRLRRIFTFQALYAGVAPSRALA
                     VYGAIAHMDTSLGVYFPEGGMRTIAESMADAFTEAGGILHLGRTVERLEVSDRRVHTVH
                     TRDGERFDCDAAVLTPDMAVTDSLLRPHTRLRPRPVRTSPSAVVIHGTVSSAVADEWPA
                     QRHHMIDFGEAWKRTFAEITARRGPGRLMSDPSLLVTRPAQTDPSLAFSRDGRIREPLS
                     VLAPCPNLDSASLDWSTLGPPYVREIILTLQERGYTGLVEGFEIDHVDTPQTWLEKGMA
                     AGSPFAAAHTFTQTGPFRRKNLARGFDNVVLAGSGTVPGVGVPTVLLSGRLAAERITGT
                     RERASAVGTRASN"
     gene            12834..14411
                     /locus_tag="LQ424_RS05970"
                     /old_locus_tag="LQ424_05965"
     CDS             12834..14411
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941737.1"
                     /locus_tag="LQ424_RS05970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05965"
                     /product="alpha-(1->6)-mannopyranosyltransferase A"
                     /protein_id="WP_042452824.1"
                     /transl_table=11
                     /translation="MTSSAAATERPWHLRAANFLRTPEGHSALLGFFGAVMITFGGFGA
                     GSVRRQDPLLESMYLSWLRFGHGSILSAAIVWIGVLCMIAAWVRLGRSTLRGDVSLRGL
                     RYVVPVWTFPLLFAVPMFSRDAYSYLAQGALLRNGFDPYAVGPVVNPGILLDNVSNVWT
                     TTTTPYGPVHLLLADAIVRLTGENVIAGTMLLRITMLPGLALMMWAVPHLATKLGGNTS
                     IALWLAVLNPLVLIHLIGGVHNEMLMVGLMAAGIALALERKHLFGIGLIALAVAIKATA
                     GVALPFIVWIWMIHEREDAAAAGREPASPIRSFVKTAGAGFAVFVAVLGSTSLIAGVGL
                     GWTTALSGSAKIINWLSLPTIVAHIGTMATSWFAGDHFNDILEVSRTISAVVLIAIIAV
                     VWWRYRKTERDAVMGIVIVMVAIVVLSPAALPWYYSWPLAVAAGFAMSPTTLAVLTGLS
                     TWLMLVFQPDGSIGLYTFPHVALAIVAAVIAAMSLQTEDPLRLRGRKHEKPIDMTSAAS
                     APSTSGSA"
     gene            14422..15366
                     /locus_tag="LQ424_RS05975"
                     /old_locus_tag="LQ424_05970"
     CDS             14422..15366
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730072.1"
                     /locus_tag="LQ424_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05970"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_042452823.1"
                     /sec_met_domain="phytoene_synt (E-value: 7.7e-91, bitscore:
                     299.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.2e-59,
                     bitscore: 195.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALPASYEFCEDVTREHGRTYFLATRLLPEPRRRAVHALYAFAR
                     VVDDIVDEPSGPHERGTVLADVERAAVNALDNPTATGGFPSTVPLDLTRVLPAFADAVK
                     TFDIPRAYFDAFFESMRMDAPDTAKFRPVYNTMDELSEYMYGSAVVIGLQMLPILGVSV
                     PQQEAVVPASNLGEAFQLTNFIRDVGEDLDRGRLYLPAGEFAAFGVDIEMLEHGRRTET
                     VDVRVKRALAHFIAVTRGRYRTAESGIPMLDRRVQPSIRTAFVLYGAILDQVERADFRI
                     LHRRVSVPGRTRLRVAAPGLVRSATYAAKNRMR"
     gene            complement(15387..15755)
                     /locus_tag="LQ424_RS05980"
                     /old_locus_tag="LQ424_05975"
     CDS             complement(15387..15755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007297456.1"
                     /locus_tag="LQ424_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05975"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_042452820.1"
                     /transl_table=11
                     /translation="MSAIPYCDDVLDSSVSLFQLVDVAKNVGLPVSKVHQLLRDHKIIA
                     VKRHGVLGVPEVFFGEDGQTVKWLPGLLAVLHDGGYTDIEILRWLFLADDSLPGRPVDA
                     LHGDLAREVIRRAQAMAF"
     gene            16075..18138
                     /gene="pknB"
                     /locus_tag="LQ424_RS05985"
                     /old_locus_tag="LQ424_05980"
     CDS             16075..18138
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730071.1"
                     /locus_tag="LQ424_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05980"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_080726733.1"
                     /sec_met_domain="Pkinase (E-value: 7.5e-50, bitscore:
                     165.0, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGEMLERRYRVDAPIARGGMSTVYRGLDTRLDRPVAIKVMDPQF
                     AGDPAFLTRFEFEARAVARLKHPALVAVYDQGSDRNHVFLVMELVDGGTLRELLRERGP
                     MPPHAVAAVVAPVLDALAVAHRAGLVHRDVKPENILISDTGEVKIADFGLVRAAAAATT
                     TSNSVILGTAAYLSPEQVTSGIADTRSDVYSTGVLMFELLTGTTPFTGDTSLSIAYQRI
                     HDDVPRPGSRIPGVPAQFDRLVAEATHREPAHRFADAGEMAAALRSVSEQLELPSYRVP
                     APRRSAQHQSAQVAPARPQPAPAPPTEVHPNSAARPNPAATTVLASGVAPAVAATTALG
                     TGSPPPGGIQHTRAVTAQTARPATVDGDSDFDDGSDFGDDHPGHDDPHAHFVEARRKSR
                     RATLIWLLVIAVLALALGFGGWWMGSGRYTAVPSIDGLTKDTAVTALQDAGLSPDVQGQ
                     YSDAQPIDTVIGTDPASGSRVTKGSTVALVTSLGRPTVPPIPAGGDVSALGAQLADRTL
                     VAVDGGDTFSSKIPIGGVAALDPAPGTEVAVGSSVKVITSKGSPPVDIPDVKGMSENAA
                     RAALDKVGISVSTTRTTFDDAVEGGSVIGTDPAVGSSVNAGTSVVLLISDSVKVPSLIG
                     RSVSSAREELGRLGLEITVRQLTQNDSSVIISQSVKNDLVAKGTDISVVAIP"
     gene            18166..18594
                     /locus_tag="LQ424_RS05990"
                     /old_locus_tag="LQ424_05985"
     CDS             18166..18594
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941706.1"
                     /locus_tag="LQ424_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05985"
                     /product="protein-tyrosine phosphatase family protein"
                     /protein_id="WP_003941706.1"
                     /transl_table=11
                     /translation="MATWEPESIGILDLPSGRSIRGRGLRNPLPSGPLPTFGVYLTGKE
                     PPDTEWESEWVRWRDFWLPSDPDALRRALHEVWVRSETERVEIACGGGYGRTGTALAAL
                     AVMDGVPSKDATAYVRARYSPRAVEMPWQRRFVTRFTQ"
     gene            complement(18678..20063)
                     /locus_tag="LQ424_RS05995"
                     /old_locus_tag="LQ424_05990"
     CDS             complement(18678..20063)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016933765.1"
                     /locus_tag="LQ424_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05990"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_007730070.1"
                     /transl_table=11
                     /translation="MNWTVDVPIDRLPELPPLPAGLRKQLDEALAKPAAQQPSWPADQA
                     AAMRTVLESVPPITVASEVEALQERLAQVARGEAFLLQGGDCAETFADNTEPHIKGNIR
                     TLLQMAVVLTYGSSMPVVKVARIAGQYAKPRSADIDSLGLKSYRGDMINSLVADEAVRA
                     HDPSRLVRAYANASAAMNLVRALTGAGMADLHKVHDWNREFVAASPAGARYEQLAAEID
                     RGLQFMNACGVTDPSLHQAQIFASHEALVLDYERAMLRLDNDSDHPKLYDLSAHFLWIG
                     DRTRQLDGAHIAFAELVSNPIGLKIGPSTTPEMAVEYVERLDPTNKPGRLTLISRMGNG
                     KVRDLLPAIIEKVQATGHQVIWQCDPMHGNTHEASTGYKTRHFDRIVDEVQGFFEVHNG
                     LGTHPGGIHVELTGENVTECLGGAQDISDLDLGGRYETACDPRLNTQQSLELAFLVAEM
                     LRG"
     misc_feature    complement(20096..20111)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            complement(20154..20645)
                     /locus_tag="LQ424_RS06000"
                     /old_locus_tag="LQ424_05995"
     CDS             complement(20154..20645)
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008408 - 3'-5' exonuclease activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012688083.1"
                     /locus_tag="LQ424_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_05995"
                     /product="polyadenylate-specific 3'-exoribonuclease AS"
                     /protein_id="WP_003941683.1"
                     /transl_table=11
                     /translation="MRYFYDCEFIEDGRTIDLVSIGVVCEDGREYYAVSTEFDPARAGS
                     WVRKNVLPKLPQPSSPLWKSREKIRDDLLKFFVPRPMVVPELWAWVAAYDHVALCQLWG
                     DMTELPQSMPRYTRELRQFWEDNGSPALPSAPADAHDALADARHNLVKFDAISAARSLR
                     "
     gene            complement(20712..21518)
                     /locus_tag="LQ424_RS06005"
                     /old_locus_tag="LQ424_06000"
     CDS             complement(20712..21518)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003941692.1"
                     /locus_tag="LQ424_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_06000"
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_042452815.1"
                     /transl_table=11
                     /translation="MWYWLFKYVLLGPILWLLGRPTVKGHENIPTDGAAILASNHQAVL
                     DSFYLPLRVNRRITFLAKSEYFTGSGLKGAFQKWFFTAVGQVPIDRTGADAAQDALNAG
                     LKVLGSGSLLGIYPEGTRSPDGRLYKGKTGMARLALESGVKVIPVAMVGTDKMNPIGSR
                     MWRPAKVTVIVGEPIDFSRFEGMGGNRFVERAVTDEVMYKLMKLSGQEYVDIYAASLKN
                     QAPTKPEAAVDVPAEGVESVVDLVASAESKESAKSDKDSLPDAQAS"
     gene            complement(21613..22653)
                     /locus_tag="LQ424_RS06010"
                     /old_locus_tag="LQ424_06005"
     CDS             complement(21613..22653)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748895.1"
                     /locus_tag="LQ424_RS06010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_06005"
                     /product="ROK family protein"
                     /protein_id="WP_020969875.1"
                     /transl_table=11
                     /translation="MSARRLKAVSDSTMDDILTVGIDVGGTSIRASVVDVDGQVLEMIQ
                     APTPQSARALEDGLDRVVRELVTRHEVSAVGLAVAGFITSDRSSVRFAPHLPWVDAPVG
                     SDLSKRLGLPVVLEHDANAAAFAEHRFGAAAGGRNVVMVAIGTGIGGALLINGELYRGS
                     HGVAPELGHIQVVPGGRQCACGKRGCWERYCSGTALVDTAIELLAADPAASTVLAREVA
                     VDPGSLTGRRIANAAQDGDPLALATIAEFTRWLAVGLAMVGDVYDPDLVVIAGGVASSA
                     PLFLDDAREQYATLLTGAKHRPLARIRSAQLGEAAGMVGAAALARSVVPQDLGGVDGAG
                     TTSAGL"
     gene            complement(22778..23173)
                     /locus_tag="LQ424_RS06015"
                     /old_locus_tag="LQ424_06010"
     CDS             complement(22778..23173)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748896.1"
                     /locus_tag="LQ424_RS06015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_06010"
                     /product="hypothetical protein"
                     /protein_id="WP_042453569.1"
                     /transl_table=11
                     /translation="MSEEHERLVAEFRALAETVLTRLEPVLQKAAAATADVASDSASTD
                     TQPVFTGCSWCPVCALAALVRGEHHELLAFLAGQAAAFLALLREILDEFLGGPSGPDRG
                     PDGGPTTPGAERTRTAAFVPINVTVKD"
     gene            complement(23170..24420)
                     /locus_tag="LQ424_RS06020"
                     /old_locus_tag="LQ424_06015"
     CDS             complement(23170..24420)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1157: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007730068.1"
                     /locus_tag="LQ424_RS06020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_06015"
                     /product="ArsA family ATPase"
                     /protein_id="WP_042452813.1"
                     /transl_table=11
                     /translation="MPEQRSRVQLFVGKGGVGTTTLAAATAVSAATDGARVLLVSIDQA
                     GSLADVLGVPNPRTTTSLTEGLDVRQLDTSALLEDKFRGLSGLIDAAGTFGAGDHEHGS
                     SFEGLEPEELTGSLGIQDMLGLAEIVDFSDSGDYDLVIVDCPAAAEALRILGSPSMVSE
                     YLERLWPRHRRMVAVTGTDMRLLLLVSVVERVLASVDRIAVHLSDRENTGVRVVTSADG
                     VSVAATRRTLSGLALAGLRVDGIVVNNLVPQFNSSAGKGVDDSPAAQWLASIRAAQALV
                     VAELRGSTDGMSVTTVERACAEPVGLAALGEIAATFEGGTGTDSGTVGTADNIVVSLES
                     GTGVDSVYVMRMYLPLVDPSSLSLGRVEDDVLVGADGVRRRVRLASVLRRCVVNGAELD
                     GSYLIIRFSPDPAVWPV"
     gene            complement(24421..24858)
                     /locus_tag="LQ424_RS06025"
                     /old_locus_tag="LQ424_06020"
     CDS             complement(24421..24858)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (8-144). E-value:
                     4.3e-18. Score: 58.0. Matches aSDomain:
                     nrpspksdomains_LQ424_RS06025_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005247694.1"
                     /locus_tag="LQ424_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_06020"
                     /product="SRPBCC family protein"
                     /protein_id="WP_003941701.1"
                     /transl_table=11
                     /translation="MAEKTKGLISIDAPADAVMDVIADFERYPEWVAAAKSVEVTAPGQ
                     GGRADRVRFVLDAGMVKDTYELQYSWAPDGMAVSWELISGEIQKSQFGSYTLEPGPNGT
                     TSVTYELTVDLTIPMIGLFKRKAEKIITDTALKELKKRVEG"
     aSDomain        complement(24427..24834)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LQ424_RS06025_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.30E-18"
                     /label="LQ424_RS06025_Polyketide_cyc2.1"
                     /locus_tag="LQ424_RS06025"
                     /protein_end="144"
                     /protein_start="8"
                     /score="58.0"
                     /tool="antismash"
                     /translation="ISIDAPADAVMDVIADFERYPEWVAAAKSVEVTAPGQGGRADRVR
                     FVLDAGMVKDTYELQYSWAPDGMAVSWELISGEIQKSQFGSYTLEPGPNGTTSVTYELT
                     VDLTIPMIGLFKRKAEKIITDTALKELKKRVE"
     misc_feature    24824..24837
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.45"
                     /tool="antismash"
     gene            complement(24922..25308)
                     /locus_tag="LQ424_RS06030"
                     /old_locus_tag="LQ424_06025"
     CDS             complement(24922..25308)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (4-55). E-value:
                     4.3e-08. Score: 25.6. Matches aSDomain:
                     nrpspksdomains_LQ424_RS06030_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019748899.1"
                     /locus_tag="LQ424_RS06030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LQ424_06025"
                     /product="polyketide cyclase / dehydrase and lipid
                     transport"
                     /protein_id="WP_042452811.1"
                     /transl_table=11
                     /translation="MSSIQVADQTFIAAPPERVAELLSSRAQWRRWFSDLELEVREDRG
                     PAGFRWGVSGQLVGTMEVWLEPVMDGTIAHYFLHCEPVGVSPSDLATLDLAGMNRNRRV
                     DGKLMSFQLKRELEAGRAAGVAPD"
     aSDomain        complement(25144..25296)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LQ424_RS06030_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.30E-08"
                     /label="LQ424_RS06030_Polyketide_cyc2.1"
                     /locus_tag="LQ424_RS06030"
                     /protein_end="55"
                     /protein_start="4"
                     /score="25.6"
                     /tool="antismash"
                     /translation="QVADQTFIAAPPERVAELLSSRAQWRRWFSDLELEVREDRGPAGF
                     RWGVSG"
ORIGIN
        1 cctcgggctg cggcgtctcg gtccgcgtgc cggaagaatc gacagtcgac ttcacgatcc
       61 gcggaggaat tcgcacgccg tcgttggcaa tggcctggta catcccggtc atctgcaggg
      121 ttgtcatcga gagaccctgc ccgatcggca ggttcgcgaa ggttccgccc gaccactggt
      181 cgcgactcgg aacgctgccc gcgctctcgc cgggaagtcc gacgtcggtg cgttgtccga
      241 ggccgaacct gttcagcatg tctgcgtagc gatcctcgcc cactcgctga gcgagcatca
      301 aggtgccgac gttcgaggac tttccgaaca caccggtaga ggtgtacggg gccacaccgt
      361 gatcccacgc gtccttgact gtggcaccgg acatcgtgat gctgcccggg acctgcagaa
      421 cttcgtccgg agttgtctta ccgtcctcga tggccgctgc tgcggtgacg atcttgttca
      481 ccgatccggg ctcgaacggc gtactgaccg acggattgcc catttcggct gtcggcgcgt
      541 tcttgtcgat gccgattgcg gggttgaagg tgctgtcgtt ggacatggcc aacacctgtc
      601 ccgtcttgga gtccatgacc acaaccgaag cgttcttcgc gcccgacttg tccttggcga
      661 tctggacctg ctgctgaacg tagaactgga ggtccgaatc gatggtcagc tcgacacccg
      721 aaccgttgac tgccggttgc ttgtcacgcc agctaccggg gatcacagcg ccgtcggaac
      781 cgcggtcata cgtttcggat ccatcggttc cggcgagcgt ggagtccatc gaatcttcga
      841 gaccgagcaa accgtgcccg tcccagccgg tcgcgccgac gagattcgcg gccagagagc
      901 caccggggta ctcgcggatg tcctgacgct cgaggccgac ctcccggaac ttgtccgaga
      961 tctcggcagc aaccgccgga tccacgctgc gcgcgaggta cgtgaaagtc tcgttgctgt
     1021 tcatcttctg aagcagatct ttttccggaa cggtatcgcc gagcttggcg tggattccgg
     1081 cggcgatctc ggcgaggcga tcgctcactt ccggcgcctg cttgtcaccc tcggcgccct
     1141 gctcgatgct cttggcgcgc gcttcctcga gttccttgcg tacccgcacc ggctggaaag
     1201 tcagcgcctt ggcttccatg gtgaaggcga gggggtttcc gttgcgatcg gttatcgagc
     1261 cacgtacagc cggatcgacc tgggtcgtgg ttcgttgatt ggcagattcc gcagccagac
     1321 tcggcgcgtc gattccctga atccacaaga gctgcaatgc cgcaacggcg agcgcaccac
     1381 acatggtgat acgaccgact cgctgacgaa acggaaatga ggcggtggcc gagcggcgcg
     1441 gacgccgacc ggggttgtta cgggagttct gactcaccga cgttcctcag gcggagcagg
     1501 caccgccgtc gtggtggcgg gtgctgtcgt cgtggggatc acaggaacca attgttcact
     1561 ctgcgcgagg tttcgcgtgt tattcggaac gctcggcgtg gctccgggag caaccggcgt
     1621 tgtggtgcgc gggggtgtcg cagtcggtgc gggcaccgat gtgggcgcat cgagcggcgg
     1681 catagctccg gcagtcgcgg gagtcggcgt tccgacgacc tcgaccgaac cgtccggatg
     1741 aactaccagt cgtgcagggt ccttggcggg gaccatgccg agagcgcttg cctgatttgc
     1801 caactccgga gccgagttac gcgactggaa gtcacgttcg agcgctgctt tctgctcgac
     1861 caaagactgg ttgtatgcac gtgcatcact gagttggtac gaatcctcgg cagcgcgagt
     1921 ggtcagcagc agagtcaccg cgagaccgat ggacagaagt ccgatgacgg aggccacgaa
     1981 cggcactctc cccttgagca tcgcccgagg agagatagac gggccggcag cagcgacagt
     2041 tccggtccgg cctgccgccc gtgcggtgcg cttgtcgtat gcacgttgcg ctgcaccgga
     2101 tttgccctga cgactcatgc ccgcctcctg gaaatgcgtt ctgcggcacg caaacgcacc
     2161 ggagctgatc gtgggttctc ttcgatttcc tgctctgacg cacgttctgc gccacgggtg
     2221 agaatgcgga actccggtcc catacccggc aactcgaccg gtagtccttc aggactggtg
     2281 gacttcgagc ggggaaccaa ctccgccttc acaactcgat cctcgagcga ctggtaggac
     2341 atgaacacca ctcgcccacc gactgccagt gcgtcgagcc cggcaggaac ggctgcacga
     2401 agcgaatcca actcggcatt gacttcgatc cgcagcgctt ggaaggtgcg cttggccggg
     2461 tgtccccccg tacgccgcgt ggctgccggg attgttcggt acagcaattc gaccagagct
     2521 gcactggtgg tgaagggttc acgctcacgc tgccgaagga tctcggacgc aatctttccc
     2581 gcgaaccgtt cttcgccgta cgtgctcaga atgcgagcaa ggtcgccgtg actgtaggtg
     2641 ttcaggacct ctgccgcggt cagcccgacc gtctgatcca tccgcatgtc gagaggagcg
     2701 tcgatcgagt acgcaaaacc tcggtcggct tcgtccaact gcatcgacga cacacccaga
     2761 tcgaaaagga tcgcgtgaac cgactccgtc gacggcagac ctgcctgttc gagcgcgtcc
     2821 tcgatcccgt cgtacgtggt gtgcacgaac gtcgttcggt ccgcgaatgg cgccagacgc
     2881 tcggaagcga tccggagtgc gttggtgtcg cgatcgagac cgatgaggtg aaggcccggg
     2941 tacttgccca ggaagaattc ggagtggcca ccgagcccca acgtcgcatc gatcatgtat
     3001 gcgcccgctc caccgtcacc gacggcggtg atggcagggc cgagaagatc gtcggcgcgg
     3061 tgcagaagta cagggacgtg cgcgaagcca tcggcatccg agggttcgtt cacctcgtga
     3121 tccaccatga ttgctccggc tcctactttc atgatttccg atgacttttc gaaaaggtgc
     3181 tgactttccg agaaggcgat gactgttcga gaaggcgaat gcttcgaggt ccctgcccga
     3241 aggagaacct ggcgctgggg aagtgcgtca gggtctttcc gggcagaggc ctcgcggcat
     3301 tcgccggggg ctcttcgcct agacgatctc gctgagagat tcgcctgttg cctgcgaata
     3361 gtcctcttcg ttgtctccga gatacctctc ccaggctgct agatcccaga tctcgaggta
     3421 atcgacggag ccggtcacta cgcattcctt ggacaggttt gcgtaacgcc gatgatcagc
     3481 cgagagggtg attcgcccct gggcatcggc gtgctgttca tctgtgccgg cggccagagc
     3541 acggacatac gcccgagctg ccggatcatt gcgtggagct gccgctgcct ttcgagcaag
     3601 cttgacgaac tcgtcccggg ggtagatggc gaggctgtga tcctgactct tggtgatcat
     3661 caatcctcct gccagttcgt ctcggaactt tgccggcaac gtgagccgac ctttgtcgtc
     3721 gagcttcggc gtgaaggtac cgaggaacac tcgacacctc ctgcgagctt gcgctgaaac
     3781 cctccctatc gagcggatcg tgcttcagct ctccgcccga acccacagta ccccactttc
     3841 ccccacaaac aaggagcaca tggtccctat tcagcatcat ttgctgataa atagcaggtc
     3901 agcgcaggtg gggagacgtg ggggaaattt gtaaccgtgt cccggcccac accgccgtca
     3961 gatcgaccct ttacgccacg atctgttgct cccccacaca aaatcgcagt acaagcgcgg
     4021 ttttcgaata gacgtgagcg ggacgaggtc tggtcgtgtg ttgcagttcg accagggtgg
     4081 aggaaagtgg agggccgagt ggagcgaagt ggaggaagcc cgcgggcatg ccctgaggca
     4141 gcaggagtgg cgagtgattc gctcgcacgt cactgattca ctcgatggat tgccggcgca
     4201 cacgtacaac acccacagca acggcgtgtg gcggtcggca accttggttg ccgaccgcca
     4261 cacgtgtggt cgtccgtgcc ctgaagaggg cgtcacgtcc gaactgcatc actctcgaag
     4321 tacgcccgaa gaagggcggg agagctagtc ctgctcgaac ctgcgtttga atcgatcttc
     4381 catccgcgac gagaatccac cgccggactt ccggccgcgt ccccgcccgg atccgccggc
     4441 actaccccta cccggcggac cggagggatg attgccacct tcggaagcgg agtcggcggc
     4501 cggcgcagac ttacgtccac caccccagag gaacaacacc cctgcgccga acatgaacaa
     4561 gaaaccgaac aggctgatga tcggaaaacc gcccggcttg agcgggagtg caacccccgc
     4621 gatcagcagg accagaccca gcacgaatag agccgctgct tggaaccgcc gtctactcga
     4681 cggcgcccgc atacggccgc ccctcacatt ggaggcgaac ttggggtctt cggcatagag
     4741 agcgctctcg atctgatcga gcatgcgctg ctcgtgctcg gagagtggca cggtacctcc
     4801 cccggcactg gaagtttggc aaccacccca cggtgtgagg cggcgggtaa tcaagttgga
     4861 cgattacctg ttttcataat acgagcagtt taggtctcgg accaccaact ccgggtacga
     4921 gttccgccac aagcgtacgt attcgtgccg aagggccccg attcggctcc atttgcctgt
     4981 gcggaccagg aaattccccg gaaacaactg ccgacacgga ccatttgttc acgacgctcg
     5041 caaatgctcg gacgcgtcct gaccgatgaa atcttcgacc gccgtgagaa aacggccgac
     5101 ctcggcgaag aatgcgtcgg aatcggagtc cgtgatcacg atcgacacgc cggtttccac
     5161 ggccgcacgc gtagaggacc accctgcgaa gaacttcgac cacgctccga acgcgggcgc
     5221 tgcggcgtcc atcagaaccc acgcgtttcc gcttcgcttg cgcttcgagc cggcaccggc
     5281 aggagctgcg gccaacactg ccccggcacc acgtagggcc gccaggtagg cacaccggaa
     5341 ccggtcggca ggatcgcccg ccccaatcgc ttcctcgaga agcgcatccg ccttccggag
     5401 cagcccccac gccacaccgg actttcccac tcgagcagtg cggtcgctgg cgtccctcgc
     5461 gccgaaggac cgcctcgccg acatcggcaa tcgagaaatt gcggcatccg acggactcga
     5521 caactcggca ggaagagttc gctggcactt cacacgttca ggcttcacac gctcggacat
     5581 cggggcacct cctgcaccgt gaggatccaa gaccaggtgg gccggagatg cccgcttccc
     5641 ttcgggcatc tccggatcac ccacatcgaa catctgttcg acctattcaa tataactgca
     5701 cccaccgaca cgccgtcaag agaagaggtg agaccggtcg acccgcagat cgcctggaca
     5761 ccacatacgg tcgacctcga tcgcgcagaa ttcgcgagtc gactccacga ggcactggcc
     5821 gtgtacgtca ccgcgatgga ctatccgcga ggaaccgagt tccatcgcgc accgatgtgg
     5881 caggagcacg cgaaccggcc tggctggaag gcagtcggcg ctttggcggt tcctcagcaa
     5941 ccgtcacacg aaaatctgcc gctggtgggg atcgcttacg ggtatcgcgg gagcccggac
     6001 cagtggtggc atcaacaggt actgcacggg cttcggcgct cgggtcgtcc ccagagcgag
     6061 atcgacgcga ttctgagcga ctacttcgaa ctcaccgaac tccacgtgca tccgaacgga
     6121 caaggtcacc ggttgggcga atcgctcttg cgtcacctcc tcgtcgatcg acccgaacgc
     6181 agtgttctgt tgtcgacacc cgaggtgtac gacgaggaca accgagcctg gcggctgtac
     6241 cgtcgcctcg gcttttgtga cgtgctccgc agatttcgtt ttgccggcga caaccggccg
     6301 ttcgcagtcc tcggccgtgg actgccgctg tgagcgcgct tctcgacgcc gtcgtcgtcg
     6361 gctccggaca caacgcgctc gtatcggccg cctacctcgc acgcgagggt tggtcggtcg
     6421 aggttctgga gaaggacacg gttctcggcg gcgccgtctc gaccgtcgag cgatttcccg
     6481 gatacaaggt ggaccggggg tcgtcggcac acctcatgat ccgacacagc ggcatcatcg
     6541 aggaactcgg actcggcgcg cacggactgc gctacatcga ctgtgacccg tgggcgttcg
     6601 cgccgcccgc cccgggcacc gacgggccgg gcatcgtgtt tcaccgcgac ctcgacgcaa
     6661 cctgctggtc catcgaacga gcatgcggga caaaggacgc cgactcctac cggcgattcg
     6721 tcgcggtctg gtcggagcgc agtcgacatg tcatgaaagc gttttccgca ccgcccaccg
     6781 gatcgaacct gatcggtgcg ttcggaggtc tcgccaccgc acgcggcaac agcgaactgt
     6841 ctcggcagtt cctcgcgcct ggcgacgcac tgctcgacga gtatttcgac agtgaggcac
     6901 tcaaagcagc gcttgcgtgg ttcggcgccc agtccgggcc tgcgatgtcg gaaccgggaa
     6961 ccgctccgat ggtcggcttc gcggccctca tgcacgtctt gccgccaggg cgagcagtcg
     7021 gtggaagcgg cgcactgagt gctgcgctgg cctcccggat ggctgtcgac ggcgccaccg
     7081 tcgcgctcgg tgacggcgtg acgtctatcc gccgaaactc gagtcactgg accgccacaa
     7141 ccgagagcgg tcgagaagtt cacgctcgca aggtaatcgc cgggtgccac atcctgacca
     7201 cgctcgacct cctgggccga gggggcttcg accgaaccac gctcgatcac tggcggcgga
     7261 aaatcagggt cggccccggc atcggcgcgg tacttcgact ggcgacatcc gcgcttccgt
     7321 cgtaccgcgg cgacgccacg acacgggaaa gtacctcggg attgcaatta ctcgtctccg
     7381 atcgcgcaca cttgcgcact gcacacggcg cagcactggc gggggaactt cctcctcgcc
     7441 ctgcggttct cggaatgagt ttcagcggaa tcgatcccac gatcgccccg gccggtcggc
     7501 atcaggtgac actgtggtcg cagtggcaac cgtatcgcct cagcggacat cgcgattggg
     7561 catcggtcgc cgaggcggag gccgaccgga tcgtcggcga gatggaggct ttcgcacccg
     7621 ggttcgccga ttccgtcctc gaccggttca ttcagactcc ccgggacatc gagtcggaat
     7681 tggggatgat cggcggaaat gtcatgcacg tcgagatgtc actcgatcag atgatgttgt
     7741 ggcgaccgct tccggaactg tccggccatc gtgttccggg agcagacggg ttgtatctga
     7801 ccggagcatc gactcatccc ggtggcggtg tgtccggagc cagcggtcgc agtgcggctc
     7861 gaatcgcact gtcggacagc cgccggggcg cgactcgtcg ttggatgcgt cgttcgagca
     7921 ggtcgtgaag gtcacccgcc gaacttcacc cgccgacacg cccccgcctc gatgactggc
     7981 tacgccacgg ctggcacgat gaccactgtg caacagtcca ccgatcccgc cgccaagccg
     8041 accagtcgga aacgtttcct gacggttgcc gcgctcgccc tcatgcttgt tcccttgctg
     8101 gccgggtgca tccgcgtgca ggtgtcgatg ggagtgtccg cgaacgatcg tgtgaccgga
     8161 caggtggtag ctgccgctat tccggcgaac gaggcggaca agggtccgca gctgacccca
     8221 ccttcgtcgc tggaggacaa gatacgggtt caggagtaca agaaggacgg gtacgtcggc
     8281 agccaagcgt tcttcagcga cttgtccttc ggtgacgtcg cccaactggg ctccatgtac
     8341 gccgaggggt ccgggtcgtt ccagatcacc ctcaagcgat ccggggacac cgtcacgctc
     8401 gacggcaagg cagacctgaa gacggttccg actcagggcg ccgacgtcca ggtcagcatc
     8461 gccttcccgg cacgggtcgg cacgaccaac ggaacacgag acggcgattc ccgggtgtcg
     8521 tggaccttgc ccgccggcga ggtgtccacg atgcgcgccg aggtcaacta cgcggaccca
     8581 agcacccgaa gcttcgccgg gtgggcagga atcatggccg ggctggcgct cggtgtcgcg
     8641 attgtcgtcg gtgcaatggc ctggatggcg cgcaatcgag caccgatcaa gcgcgcgccg
     8701 gccgcgaaag caccggtcat gaagacgcct gtcacgaaat cacctgccag caagcaagct
     8761 gacaacagga atccgaaaaa caccacgaag tagcgcctgg cgattgcccc cctcgattgg
     8821 tgtcgagcgg ggcaacggga tcagacggct tgtgctgtcc cgacagaggt gtcgggggtg
     8881 agaccgagtc gctcgaggac ctcactggtg gcgcgcgcaa agttcaaagt gatgaagtgc
     8941 aggcacggag cgccttcggc gatcaaccgc tcacccatct cggtggccag atcgatgccg
     9001 agttcgcgga ccgctgcacg gttctcgtcc ggaccgcttc cggccgcggc gtcgaatcga
     9061 cgctcgagag cggggggcaa tgacgagccc gagagctcga gcatgcgccg caccgagcgt
     9121 agcgacgtca ccggcatgat ctccgggatg atcggcttgg cgccctgttc tgcgtcgtac
     9181 gcactcaccc ggtcacgaag acgcaggtag tcctccacgt cgaagaacat ctgtgtgatc
     9241 gagtactcgg cgccggcacg caacttcgac accaggtact tcgtgtcgta ggccaagtcc
     9301 ggagcgcgat agtgcccctc ggggaacgac gcgacgccga cgtggaagtc gcccaggtca
     9361 cggaccatcc gtacgagttc ctcggcgtac tcgacgcctt cgggatgctt cttccattcg
     9421 ccgagcggat cgccgggcgg atcgccgcgc aatacgagga tgttgctgat cccacgatcg
     9481 gcgtaggcac cgaccatggc gcgaagctct tcggtgctgt gtgagacagc agtcaggtga
     9541 gcaaccggca gcagggtcgt ctcttcggca agttcgccgg tgacacgcac cgtacgatcg
     9601 cgcgtcgagc cacctgcgcc gtaggtcatc gagacgaacg ccggtccgag ccgctcgaag
     9661 gtacgcaccg cacgccacag gcgcgcttcg gcgtccgcgt cacgcggcgg cgaaaactcg
     9721 accgagaacg gaatacggct acctgtcgag gaagcgatcc gatcgacgat cgacggtgtt
     9781 cgggtggccc acccctcgct ggagcggccc ctgactggat cgaatgtcac cggtcaagca
     9841 tatgttttcc agctgcaaac aagctcatcg cccagtactg cgtatcccga atgtcaggat
     9901 cgcgcagttc acggcccgac ccgccgttga ttccaacccc tactaagctg ggccccaagc
     9961 tcgcttccgt gtaaccatcc ggcgcgagaa cataccgatc ttggaggcca ccctgtccgc
    10021 aggaaccgcg cgcgttggac agagttcgac caacaccgca ccgcatccga cctcactcga
    10081 actgccaggt ctgttcgaag cagcgctccg cgacttcttc gcttcacgcc gcgaactcgt
    10141 ctcgaacata ggcggtggat acgaggaggc cgtcagcacc ctcgaggcct tcgtcctgcg
    10201 cggaggaaag cgcgtccgac cgtcgttcgc ctggacggga tggctcggcg ccggaggcga
    10261 cccgaacggt aagggcgcag acgcggtgat tcgtgcgtgc gccgccctcg aactggtgca
    10321 ggcctgcgcg ctcgtccacg acgacatcat cgacgcatcc acgaccaggc gcggcttccc
    10381 gaccgttcat gtcgaattcg aggaccagca ccgagacgag gagtggagcg gcgattccgc
    10441 gcacttcggc gaggccgtcg ccattcttct cggcgacctg gccttggcct gggcggacga
    10501 catgatccga gaatccggga tcagccccga ggcggccgca cgtgtcagcc cggtctggtc
    10561 ggcaatgcgc accgaggtgc tcggtggcca attcctcgac atcagcaatg aagcccgagg
    10621 cgacgagacc gtcgaggcag ccatgcgggt caaccgctac aagaccgccg cgtacacgat
    10681 cgaacgccca ctgcacctcg gcgccgcgct gttcggtgcg gacgccgagt tggtcgacgc
    10741 ctaccggacc ttcggcacgg acatcggtat cgccttccaa cttcgcgacg acctgctcgg
    10801 tgtcttcgga gatccgtccg tcacgggcaa accgtcgggc gacgatctca tcgccggtaa
    10861 gcgaactgtc ctgttcgcga tggcgcttgc ccgcgccgac gccgcagatc cggcggcagc
    10921 agaactgctc cgcaacggaa tcggcacgca gctgaccgac accgaggtcg acactctgcg
    10981 ccaggtgatc accgatctgg gcgccgtcac cgacgtcgaa acgcagatcg acaccctcgt
    11041 cgaggcagct gcgaacgccc tcgactcgag cacggcaacg gcagagtcca aggctcgcct
    11101 gaccgacatg gcgatcgcgg ccacgaagcg aagctactga ccgtggcaca cgtgcaccgc
    11161 actcgaaccg tcagctcgcc gaccgatcga gtcgtgatcg tcggcgcggg acttgccgga
    11221 ctgtctgcgg ggttgtatct gcgtggcgcc ggccgcgacg tcacgattct cgagagcaac
    11281 agctcggtcg gtgggcgagt cggtgtctac cagggcaatg actacagcat cgacaacggc
    11341 gcaacggtgc tcacgatgcc cgaactcgtc gaagacgccc ttgcggccgt cggcgccgac
    11401 ccagcctcga caaaccccaa attcgttgtg cacaagctcg atccgacgta ccacgcgcga
    11461 ttcgcagacg gcaccgctct cgatgtccac gccgacccag aagacatggc tgccgaagtc
    11521 tcccgtgtct gcgggccgga agaagcgcag cgataccgtg cgttgcggcg atggctgaac
    11581 cggatcttcg acgcggaatt cgaccgcttc atggacgccg acttcgattc tcccctcgga
    11641 ctggtcaatt cgcgtgacgc agtcaaagat ctgagccggc tcgtcgcact gggaggattc
    11701 gggaaactgg gcgggcaggt ggatcgcaag atccgcgacc ctcgcctccg gcggatcttc
    11761 accttccaag cgctgtatgc gggcgttgct ccgtctcggg ccctcgcggt gtacggggcg
    11821 atcgctcaca tggacacctc actcggcgtc tacttccccg agggcgggat gcgcacgatc
    11881 gccgagtcga tggccgacgc cttcaccgag gccggcggaa ttctgcatct cggccgcact
    11941 gtcgaacgcc tcgaggtaag cgatcggcgc gtgcacaccg ttcacacacg cgacggcgag
    12001 cgcttcgact gtgacgccgc cgtcctcact cccgacatgg ccgtcacgga ctcgctgttg
    12061 cgcccgcata cgcgattgcg tccgcgcccg gtgcgtacat cgccgtccgc tgtcgtgatt
    12121 cacggcactg tttcctccgc ggtcgccgac gaatggcccg cgcagcgaca ccacatgatc
    12181 gacttcggcg aggcgtggaa gcgtaccttc gccgagatca cggcacgccg cggccccggg
    12241 cgactgatga gtgatccgtc actgctcgtc acccgaccgg cacagaccga tccgagcctg
    12301 gccttctcgc gagacggccg aatccgtgaa ccgctgtcag tcctcgcgcc gtgtccgaat
    12361 ctggacagtg caagtctcga ctggtcgact ctcggcccgc cctacgtgcg cgaaatcatc
    12421 ctcacgctgc aagaacgtgg ctacacggga ctggtcgaag ggttcgagat cgatcacgtc
    12481 gacaccccgc agacctggct cgagaagggc atggccgcgg gtagcccgtt cgcagcggca
    12541 cacaccttca cccagacggg gccgttccga cgcaagaacc tcgcccgcgg cttcgacaac
    12601 gtcgttctcg ccggatcggg aaccgttccg ggggtgggag taccgaccgt tctgctgtcc
    12661 ggacggctcg ccgccgaacg tattaccggt acacgcgagc gagccagcgc ggtgggcact
    12721 cgtgcgagca actaaactgg cccctcgtaa ccgaccattc atccacgatt caccgactcg
    12781 ggcgctgcac gcgccgatcg acaccgatct cctcggggga ggaacctgca ccgatgacgt
    12841 cctctgccgc agccactgaa agaccgtggc acctaagggc cgccaatttc cttcggactc
    12901 ccgaaggtca cagtgcactg ctcggtttct tcggcgcagt catgatcact ttcggcggat
    12961 tcggtgccgg tagcgtccgg cgccaagatc cgctgctcga gtcgatgtat ctgtcctggc
    13021 tccgtttcgg ccacggatcg attctgtcgg cggccatcgt ctggatcggt gtcctgtgca
    13081 tgatcgccgc ctgggttcga ctgggccgct cgactctgcg cggtgacgtc tcgttgcgcg
    13141 gattgcgcta cgtcgtcccg gtctggacgt ttccgctgct gttcgcggtg cccatgttca
    13201 gccgtgacgc ctactcctac ctggcgcaag gcgcgttgtt gcgcaacggc ttcgacccgt
    13261 atgccgtcgg ccccgtcgtc aatccgggaa tcctgctcga caacgtctcc aacgtgtgga
    13321 cgacgacaac taccccgtac ggtccggttc accttctcct tgccgacgcc atcgttcggc
    13381 tgaccggtga gaacgtcatc gccggcacga tgctgttgcg gatcacgatg ctccccggac
    13441 tcgccctgat gatgtgggcc gttccccatc tcgcgacgaa gctcggcgga aacacctcga
    13501 tcgccctgtg gctcgcagta ctcaatcccc tcgtcctgat ccacctgatc ggcggcgttc
    13561 acaacgagat gctcatggtc ggcctcatgg ccgcaggcat tgcgctcgct ctcgaacgca
    13621 agcacctctt cgggatcggg ctgatcgcgc tcgccgtcgc gatcaaggca accgcaggcg
    13681 tcgcacttcc cttcatagtc tggatctgga tgatccacga gcgggaggac gccgcagcgg
    13741 ccgggcgaga accggcgtca ccgatccgat cgttcgtcaa aacggccggc gcaggtttcg
    13801 cggtgttcgt ggcggtactc ggatccacct cactgatcgc cggagtcggc ctcggctgga
    13861 cgacggcact ctccggttcg gcaaagatca tcaactggct ctcgctgccc acgatcgtgg
    13921 cgcacatcgg aaccatggca acctcctggt tcgccggcga ccatttcaac gacatcctcg
    13981 aagtctcccg gaccatctcg gcggttgtgt tgatcgcgat catcgccgtc gtgtggtggc
    14041 gctaccgcaa gaccgagcgc gacgccgtca tgggcatcgt gatcgtgatg gtcgccatcg
    14101 tcgttctgtc ccccgcagca ctcccctggt actactcctg gccactggca gtagctgccg
    14161 gtttcgcaat gtcgccgacg actctcgccg tactgaccgg gctgtccacc tggctgatgc
    14221 tggtgttcca gccggacgga tcgatcggcc tctacacctt cccgcacgtg gctctggcca
    14281 tcgtcgctgc cgtgatcgcg gcgatgtcct tgcagacgga agatccactg cgacttcgtg
    14341 gacgcaaaca cgagaaaccg atcgacatga cgtcagccgc ctcggcgccc tcgacgtcag
    14401 gatctgcgtg atccgcgtgt catgaacgca ctgcctgcgt cctatgaatt ctgcgaggac
    14461 gtgacgaggg aacacggccg aacgtacttt ctggccaccc ggttgttgcc cgaacctcga
    14521 cgccgcgcag ttcacgcgct ctacgcattt gctcgcgtcg tcgacgacat cgtggacgaa
    14581 ccctcgggtc cgcatgaacg aggcacggtg ctcgccgacg tcgaacgtgc agccgtcaac
    14641 gcactcgaca accccactgc gacaggtggc ttcccgtcga cggttcccct cgacctgaca
    14701 cgcgtactcc cggccttcgc ggatgctgtg aagacgttcg acatcccgcg cgcatatttc
    14761 gatgccttct tcgagtccat gcggatggac gcccccgaca cggcgaagtt tcgacccgtt
    14821 tacaacacga tggacgaact cagcgagtac atgtacggct ctgccgtcgt catcggtttg
    14881 cagatgctcc cgattctcgg agtgagcgtt ccgcagcagg aagcggtagt gcccgcgtcg
    14941 aatctcggtg aggcgtttca gctgaccaac ttcatccgcg acgtcggtga agacctcgac
    15001 cggggacgtc tgtatctacc ggcgggcgag ttcgccgcat tcggggtcga catcgagatg
    15061 ctcgaacatg ggcgaagaac cgaaacggtg gacgttcggg tgaagcgcgc gctggcacac
    15121 ttcatcgccg tgacgcgggg gcggtatcgg accgccgaat ccggcatccc gatgctcgac
    15181 cgacgggtcc agccgtcgat ccgcacggct ttcgtgttgt atggagcaat tctcgatcag
    15241 gtcgagcgcg ccgacttccg gatactgcat cgacgtgtgt ccgttccagg acgcacgcga
    15301 cttcgagtcg ctgcgccggg tctggtccgg tcggcaacct acgcggcgaa aaaccgcatg
    15361 cggtgagttg tcagaaggcc ggcagctcag aaagccatgg cctgtgcgcg gcggatgacc
    15421 tcacgcgcga gatcaccatg cagtgcgtcc accgggcgcc ccggcaggga atcgtcggcc
    15481 aggaacaacc agcggaggat ttcgatgtcg gtgtaaccgc cgtcgtgcag caccgccagc
    15541 agaccgggca gccacttgac ggtctggccg tcctcgccga agaacacttc ggggacaccg
    15601 agaacgccat gccgcttgac tgcgatgatc ttgtgatcgc gaagcaactg gtgaaccttg
    15661 ctcaccggca acccgacgtt cttcgccaca tccaccagct ggaacaggga aaccgaagaa
    15721 tccaggacat catcacaata aggaatcgcg ctcaccgcga gaagtttatc cggtccggcg
    15781 agcccgctgt gtaccgcccg gtgcagtgct cgaaactgcc gctccgctca ggtcacagcg
    15841 ctctgtgacg ttctcgagac ttccgcgtcg gtatcgctgg ctacgatgga cgggatgcgg
    15901 cgtatcagta accgggattt cgcggtggat gtgaatcggt gccctcactg cgggaaccgg
    15961 tacgcggtat acaaccaccc acattgctga cagctaccac ccagaccgca agtagacaga
    16021 tcacaagcac gcagatcgca agcacggagg aacagtcatt acggaggtcg agggttgatc
    16081 ggcgaaatgc tcgagcgccg ctatcgagtg gacgcaccga tcgcgcgcgg cggtatgtcg
    16141 accgtgtatc gaggcctcga tacacggttg gatcgacctg tcgcgatcaa ggtgatggac
    16201 ccgcaattcg ccggcgatcc agcgttcctg actcgtttcg agttcgaggc ccgggccgtg
    16261 gcccgactca agcatccggc ccttgtggcc gtctacgacc aaggcagcga tcgcaatcac
    16321 gtgttcctcg tgatggaact cgtcgacggt ggaaccttgc gtgaactcct tcgtgagcgc
    16381 ggaccgatgc cgccacacgc agtcgctgca gtcgtggcac ctgtcctgga cgcgttggcg
    16441 gtggcgcatc gagcgggact ggttcaccgt gacgtcaaac ccgagaacat cttgatctcg
    16501 gacaccggcg aagtgaagat cgccgacttc ggattggtgc gtgcagctgc ggcagcaacc
    16561 accacctcca acagcgtgat cctcggcacc gcggcctatc tgtcgccgga acaggtgacg
    16621 tcaggaattg ccgacactcg aagcgacgtc tactcgaccg gtgtgttgat gttcgaactt
    16681 ctcaccggta caacaccgtt caccggcgat acgtcactct ccatcgccta ccaacgcatc
    16741 cacgacgatg tcccgcgccc aggttcacgt atccccggtg taccggcgca gttcgatcgt
    16801 ctggttgccg aagccactca ccgcgagccc gcacatcgtt tcgccgacgc cggtgagatg
    16861 gcagctgcac ttcgcagtgt gagcgagcaa ctggaacttc cgtcataccg cgttcccgct
    16921 ccgcgtcgaa gcgcccagca ccagagcgcg caagttgccc cggcccggcc acaaccggcg
    16981 cctgcgcctc ccacggaggt acacccgaac tctgctgcgc gcccgaaccc tgctgccacg
    17041 acggtattgg cgtccggcgt ggccccggct gtggcagcca ccacggcgct cggcacgggc
    17101 tctcctcccc ctggcggtat ccagcacact cgcgcggtca ccgcacaaac tgctcgtccg
    17161 gcgacggtcg acggcgactc ggatttcgac gacggttccg atttcggcga cgaccacccg
    17221 gggcacgacg atccgcatgc tcattttgtc gaggcacgac gcaaatcgcg acgagccacc
    17281 ctgatctggc tgctcgtcat cgcggtcctc gcgctcgcgt tgggcttcgg cggatggtgg
    17341 atgggatcgg gccgctatac agccgttccc tcgatcgacg ggctgacaaa ggacactgcg
    17401 gtcaccgctc tgcaggacgc cgggctctcc cccgacgtcc agggtcagta ctccgacgcc
    17461 caacccatcg acacggtgat cgggacagac ccggcctccg gctccagggt taccaaaggc
    17521 tcgaccgtcg cgctggtgac ttcgctcggg cgtccgactg tcccgcccat tccggccggc
    17581 ggcgacgtct cggccctggg cgcacaactc gccgatcgca ctctcgtcgc ggtcgacggc
    17641 ggggacacat tcagctccaa gatcccgatc ggcggcgtgg ccgcgctcga cccggcaccg
    17701 ggaaccgaag ttgccgtggg ctcctcggtc aaggtcatca catccaaagg gtcaccgccc
    17761 gtggacattc ccgatgtgaa gggcatgtcc gagaacgctg cgcgcgccgc cctcgacaag
    17821 gtaggcatct cagtcagcac caccagaaca acgttcgacg acgccgtcga gggcggtagc
    17881 gtgatcggca ccgatcccgc agtcgggtcc tccgtcaacg ccggcacctc cgtggttctc
    17941 ctcatctccg attccgtcaa ggttccctcg ctgatcggcc gctccgtctc ctcagcacgc
    18001 gaagaactcg gccgcctcgg cctcgagatc accgtgcgtc agctcaccca gaacgacagc
    18061 tcggtcatca tcagccagag cgtcaagaac gacctcgttg ccaagggcac cgacatcagc
    18121 gtcgtcgcaa ttccctgaca gtccgcttcg gcctaatctg aattcatggc cacgtgggaa
    18181 cccgagagca ttgggatact cgacttgccg tcggggagat cgattcgggg tcgaggactc
    18241 cgcaatccac ttccttccgg acctctcccc accttcggcg tctatctgac cggcaaagaa
    18301 cctcccgaca ccgaatggga gtcggagtgg gtccgctggc gagatttctg gttgccgagc
    18361 gatcccgatg cgctgcgcag ggccttgcac gaagtgtggg tgcgctcgga aaccgaaaga
    18421 gtcgagatcg cttgtggtgg tggatacggc cgcaccggaa cagcgttggc cgctcttgcc
    18481 gtcatggacg gagtgcccag taaggacgcc accgcgtacg ttcgcgcacg ttactcacct
    18541 cgcgccgtcg aaatgccctg gcagcgccga ttcgtcacac gattcacgca atagcgaacg
    18601 cccccacctg cgcgagcggg tgagggcgtt tgccgacaat ctatgccggc gcgaatcagc
    18661 ttcggcgaag caaggtttca gcctcgcagc atctcggcca cgaggaacgc gagctccaac
    18721 gactgttggg tgttcaatcg ggggtcgcac gccgtctcgt agcgaccgcc gagatcgagg
    18781 tcggagatgt cctgcgcgcc gccgaggcac tcggtgacgt tctcaccggt cagctcgacg
    18841 tggatgccac ccggatgcgt gccgagaccg ttgtggacct cgaagaatcc ctggacctcg
    18901 tcgacgatgc ggtcgaagtg gcgcgtcttg tacccggtgg aggcttcgtg ggtgttgccg
    18961 tgcatcggat cgcactgcca gatgacctgg tgaccggtgg cttggacctt ctcgatgatc
    19021 gccggcagca ggtcgcggac cttgccgttg cccatgcgcg agatcagagt cagacgacct
    19081 ggcttgttgg tggggtcgag acgctcgacg tattccaccg ccatttccgg cgtcgtgctc
    19141 gggccgatct tgaggccgat cgggttggac accaactcgg cgaaggcgat gtgcgcgccg
    19201 tcgagctgac gagtgcggtc accgatccag aggaagtgag ccgacaggtc gtagagcttg
    19261 gggtgatcgc tgtcgttgtc gagacgcagc atcgcgcgct cgtagtcgag aaccagggcc
    19321 tcgtggctgg caaagatctg tgcctggtgc aggctcggat cggtgacgcc acacgcgttc
    19381 atgaactgca ggccgcggtc gatctcggct gccagttgct cgtagcgtgc tcccgcggga
    19441 gacgctgcga cgaattcgcg gttccaatcg tgcaccttgt gcaggtcggc catgccggcg
    19501 ccggtgagtg cgcgaaccag gttcatcgcg gcgctggcgt tggcgtatgc acgcaccagt
    19561 cgcgaaggat cgtgggcgcg gactgcctcg tcggcgacga gcgagttgat catgtcgccg
    19621 cggtaggact tcagacccaa cgagtcgatg tcggccgagc gcggtttggc gtactggccg
    19681 gcgatgcgag cgaccttgac gaccggcatc gaggaaccgt aggtgagcac gacggccatc
    19741 tgcagcaacg tgcggatgtt tcccttgatg tgcggctcgg tgttgtccgc gaaggtctcg
    19801 gcgcagtcac cgccctggag cagaaatgcc tcaccacgcg cgacctgcgc gagacgctct
    19861 tgcagcgcct cgacttcgct ggccaccgtg atgggaggca cgctctcgag cacagtccgc
    19921 atggcggccg cctggtcagc gggccacgag ggctgctgag cagcgggctt cgcgagcgcc
    19981 tcgtcgagct gcttacgcag tccggcaggc agcggcggga gttcgggcaa gcggtcgatc
    20041 ggcacgtcga cagtccagtt cacctctaca ggatattcgc tcgctcgtcg gcgcgtcaca
    20101 caggctctcg atcgcagccc aatcggaaca cttcccgcgc accgaaacct gggtcagcga
    20161 agtgaccgtg cagccgaaat ggcgtcgaac ttcacgaggt tgtgcctggc gtcggcaagt
    20221 gcgtcgtgtg cgtcggcggg cgccgacggg agggcaggac tgccgttgtc ttcccagaac
    20281 tgtcggagtt cgcgggtgta ccgcggcatc gactgcggta gttccgtcat gtcgccccac
    20341 aactggcaca gcgcgacgtg gtcgtaggcg gcgacccacg cccagagctc cggaaccacc
    20401 atcggccgcg gaacgaagaa tttcagaaga tcgtcgcgga tcttctcgcg tgatttccac
    20461 agcggcgacg aaggctgcgg caacttcggc agcacgttct tgcgcaccca actaccggca
    20521 cgggcgggat cgaactccgt cgagacagcg taatactctc ggccgtcctc acagacaacg
    20581 ccgatggaca cgagatcgat ggttcgaccg tcttcgatga attcacagtc gtagaagtag
    20641 cgcacgtccg aaaactatgc cgcacgcgca ggctctggag ccaatgcgcg tgcggccggt
    20701 gtgggaaatc tctagctggc ttgtgcgtcc gggagcgaat ccttgtcgga cttcgcggat
    20761 tccttcgact cggccgaggc cacgagatcg acaaccgact cgacgccttc cgccggaacg
    20821 tcgacggcag cttcgggttt cgtgggcgcc tggttcttga ggcttgccgc gtagatgtcc
    20881 acgtactcct ggccggagag tttcatcaac ttgtacatca cctcgtcggt cacagcgcgc
    20941 tcgacgaagc ggtttccgcc catgccttcg aagcgggaga aatcgatggg ttcgccgaca
    21001 atcacggtga ccttggcggg acgccacatc cgtgagccga tcggattcat cttgtcggtg
    21061 ccgaccatcg ctaccgggat caccttgacg cccgattcaa gtgcgaggcg cgccattccg
    21121 gtcttgccct tgtagaggcg accgtcaggc gagcgcgtcc cctcggggta gatacccagc
    21181 aggctgcccg aaccgaggac cttgagaccg gcgttgagtg catcctgcgc cgcgtctgca
    21241 ccggttcggt cgatggggac ctgaccgacc gcggtgaaga accacttctg gaaagcgccc
    21301 ttcagaccgg aaccggtgaa gtactcactc ttggcaagga acgtgatgcg gcggttgacg
    21361 cgaagcggaa ggtagaacga gtccagaacc gcctggtgat tgctggccag aatggccgcc
    21421 ccgtcagtcg gaatgttctc gtgacccttg accgtcggac gcccgagcag ccagagaatc
    21481 ggccccagca acacatactt gaagagccaa taccacacgg cgtccctccc attcacagct
    21541 gaatttcgct gagtacgacc ttactgccga ccggtaaccc ccgctacaca cgcccctgca
    21601 ggatcgaccc gatcacagtc cggcagacgt ggttccagcg ccgtcgaccc caccgagatc
    21661 ctgaggcact accgatcggg ccaatgcggc ggcgccgacc atgcccgcag cttcgcccag
    21721 ctgagcggaa cggatgcggg ccagtgggcg gtgcttcgcc ccggtcaaca atgtcgcgta
    21781 ttgctcgcgg gcgtcgtcga gaaacagtgg ggcagaactc gcgacgccgc cggcgatcac
    21841 gaccagatcg ggatcgtaga cgtcaccgac catggccaga cccacggcca gccaacgggt
    21901 gaactcggcg atcgttgcca gcgcgagtgg gtcaccgtcc tgcgcggcgt tggcgatccg
    21961 gcgaccggtg agcgaaccag gatccaccgc tacctcgcgc gccaggaccg tcgacgcggc
    22021 cgggtcggcg gcaagcagtt cgattgccgt gtcgacgagc gccgttccgc tgcaatagcg
    22081 ctcccaacac ccacgtttgc cacacgcgca ctgacgcccg cccggaacga cctggatgtg
    22141 gcccagttcg ggggcgacgc cgtgactccc ccggtacagc tcaccgttga tcagcagcgc
    22201 tccaccgatt ccggtcccga ttgccaccat cacgacattg cggccacctg cggccgcgcc
    22261 gaatcggtgc tccgcgaacg ccgctgcatt ggcgtcgtgt tcgagaacga ccggcaagcc
    22321 gagccgcttg ctcaagtcac ttccgaccgg cgcgtccacc catggcaagt gcggagcgaa
    22381 ccgaaccgag cttcgatcgg aggtgatgaa gccggcgacc gccaacccca cggccgatac
    22441 ctcgtgcctg gtgaccaatt cgcgcacgac gcgatcgaga ccgtcttcga gtgccctggc
    22501 cgactgcggg gtcggggctt gaatcatctc gagcacttgt ccgtcgacgt ccacgacgga
    22561 ggccctgata ctcgtcccgc cgacgtcgat gccgaccgtc aagatgtcgt ccatggtgga
    22621 gtcggagacc gctttcaagc ggcgcgcgct catcgcgacg attcccgcgc gagcggcgtc
    22681 cgctggagtg cgcaccctga atcggtgcct cgtgcgtcgg tgaccattgt gtcgattgtg
    22741 ctcatctcgg gccgttcgct ctacccgggg tactgagtca gtccttgacc gtcacgttga
    22801 tcgggacaaa tgccgccgtg cgagttcgct ccgcacctgg cgtcgtcgga ccgccgtccg
    22861 gtccacgatc gggacctgac ggccccccga gaaactcgtc gagaatctca cgaagcaacg
    22921 caaggaatgc tgctgcttga cccgcgagga atgccaacag ttcgtggtgc tcaccgcgaa
    22981 ccagtgcggc gagggcgcac accgggcacc agctgcagcc ggtgaacacc ggctgcgtgt
    23041 ccgtggacgc cgagtcactc gcaacgtctg ccgtcgctgc tgcggccttc tgcagcaccg
    23101 gttccaggcg cgtcagaacg gtttccgcca gcgcgcgaaa ctccgcgacg aggcgctcgt
    23161 gctcttcgct cataccggcc acaccgcggg atccgggctg aaccggatga tcaggtaact
    23221 gccgtccaac tccgccccgt tcacgacaca acgacgcagc accgacgcca aacgaactct
    23281 gcgtcgtacg ccgtctgctc ccaccagcac atcgtcctcc acccggccca acgacaacga
    23341 cgacggatcc acgagcggaa ggtacatccg catcacgtac accgaatcga ctccggtccc
    23401 ggactccaac gacaccacga tgttgtccgc ggtaccgacg gtgcccgaat ccgtgcccgt
    23461 tccaccctcg aacgtggccg cgatctcgcc cagagcggcc aaccctaccg gttcggcgca
    23521 agcgcgttcg accgttgtga cggacattcc atcggttgat ccacgcagtt cggccacgac
    23581 gagtgcctga gccgcccgga tcgacgcgag ccactgcgcc gccggtgaat cgtcgacacc
    23641 cttcccggcg gacgagttga actgcgggac aaggttgttg accacaatcc cgtcaactcg
    23701 caacccggcc agagccagcc cggacaacgt ccgacgagtc gccgcgaccg acacgccgtc
    23761 ggccgacgtc accacacgca cgccggtgtt ctcccgatcc gagaggtgaa ccgcgatccg
    23821 atccaccgac gcgagcacgc gttcgacgac ggacacgagc aggagcagcc gcatgtccgt
    23881 acctgtcaca gcgaccatcc gcctgtgccg cggccacaat cgctcgagat actccgacac
    23941 catcgacggc gagccgagta tccgcagcgc ttcggcggcg gccggacagt ccacgatcac
    24001 gaggtcgtag tcgccgctgt ccgagaagtc gacgatctcg gcgagcccga gcatgtcttg
    24061 gatgcccagg gatcccgtca actcttccgg ttccaagccc tcgaacgacg aaccgtgttc
    24121 gtgatctccc gctccgaaag ttcctgcagc gtcgatcaac cccgacaatc ctcggaactt
    24181 gtcctcgagg agcgctgacg tgtcgagttg ccggacgtcg agaccctcgg tgagagatgt
    24241 ggtcgttcgc ggattcggca cgcccaggac gtccgcaaga gaacctgcct gatcgatcga
    24301 cacgagcagc actctcgccc catcggtcgc agccgacaca gcagtcgctg cggcaagcgt
    24361 cgtcgtgcct actccgcctt taccgacgaa cagttggacg cgcgatcgtt gctccggcac
    24421 tcagccctcg actcgcttct tcagttcctt cagagctgtg tcggtgatga tcttctcggc
    24481 cttgcgcttg aacagtccga tcatcggaat cgtcaggtcg accgtcaact cgtaggtgac
    24541 cgacgtggtg ccgttcgggc cgggctcgag tgtgtacgaa ccgaattggg acttctgaat
    24601 ctcgcccgag atcagctccc aactcaccgc cataccgtcc ggtgcccacg aatactgcag
    24661 ttcgtaggtg tccttcacca tccccgcgtc gaggacgaaa cgtactcggt ccgcgcggcc
    24721 gccctgtccc ggcgccgtca cctcgacgga cttcgccgcg gccacccact cggggtaccg
    24781 ctcgaaatcg gcgatgacgt ccatcacggc gtcggcagga gcgtcgatgc tgatcaaccc
    24841 cttggtcttc tcggccatac gactgcgcta ccttccttcg tcaaaagtcc agaacctgca
    24901 caacgtgcag tgcttcgatt atcagtccgg tgctactccg gcggcacgtc ccgcttcgag
    24961 ttcgcgcttg agctggaacg acatgagctt gccatcgacc cgacgattgc ggttcatccc
    25021 ggcgaggtcg agggtcgcca gatcggacgg cgatacgccg accggctcac agtgcaggaa
    25081 gtagtgcgcg atcgtcccgt ccatgaccgg ttcgagccac acctccatgg tgccgaccag
    25141 ctgaccggac actccccaac ggaatcctgc gggaccgcga tcttcccgga cttcgagctc
    25201 gagatcactg aaccagcgac gccactgcgc gcgcgaggac aacagttcgg cgacccgctc
    25261 gggcggggcg gcgatgaaag tctggtctgc gacctgaatg ctgctcaccg aagtagcttc
    25321 acatatcgcg tccgcgaagc gtcgaggggt gtcgcaacac tacata
//
