LOCUS       NZ_CP084582            20951 bp    DNA     circular CON 11-FEB-2024
DEFINITION  Micromonospora aurantiaca strain G9 chromosome, complete genome.
ACCESSION   NZ_CP084582
VERSION     NZ_CP084582.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora aurantiaca
  ORGANISM  Micromonospora aurantiaca
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7149079)
  AUTHORS   Schneider,B., Pfeiffer,F., Dyall-Smith,M. and Kunte,H.J.
  TITLE     Genome Sequence of Micromonospora aurantiaca Strain G9, a Member of
            a Bacterial Consortium Capable of Polyethylene Degradation
  JOURNAL   Microbiol Resour Announc 11 (5), e0114821 (2022)
   PUBMED   35389268
REFERENCE   2  (bases 1 to 7149079)
  AUTHORS   Schneider,B., Dyall-Smith,M., Pfeiffer,F. and Kunte,H.-J.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-OCT-2021) 4.1, BAM Bundesanstalt fuer
            Materialforschung und -pruefung, 12205 Berlin, Unter den Eichen 87,
            Berlin, Berlin 12205, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. SEPT-2021
            Assembly Name                     :: BAM_Maura_1.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 427.0x
            Sequencing Technology             :: PacBio Sequel
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/11/2024 09:59:34
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,512
            CDSs (total)                      :: 6,447
            Genes (coding)                    :: 6,372
            CDSs (with protein)               :: 6,372
            Genes (RNA)                       :: 65
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 25 of 75
            Pseudo Genes (incomplete)         :: 59 of 75
            Pseudo Genes (internal stop)      :: 6 of 75
            Pseudo Genes (multiple problems)  :: 15 of 75
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:21:19
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5266656
            Orig. end                         :: 5287607
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084582.1.
            Bacteria and source DNA available from BAM, FB 4.1, Hans Joerg
            Kunte, Unter den Eichen 87, 12205 Berlin, Germany.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20951
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20951
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20951
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10951](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10951
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(<513..1163)
                     /locus_tag="LF814_RS23620"
                     /old_locus_tag="LF814_23645"
                     /pseudo=""
     CDS             complement(<513..1163)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037778.4"
                     /locus_tag="LF814_RS23620"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23645"
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRGSHARRAATEHSDVDVDVLVVADDGRTAGTGARQTASRRGMP
                     YAARRAYLTEFAGRLVHVSVAARDVRSWVRRLGQPADWAFGLPVTAPARLLWAVPEWRR
                     RIDLPVLCQPADEPRLEELIATLGKVAAARVADDPVGVRLAAADLARLCPSVLRPANPS
                     VRVVSRRAALTAALDLPVAPPGYRHDMLLCLGLRAGDPAEVGAAAGRLVTGILP"
     gene            complement(1326..1715)
                     /locus_tag="LF814_RS23625"
                     /old_locus_tag="LF814_23650"
     CDS             complement(1326..1715)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287558.1"
                     /locus_tag="LF814_RS23625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23650"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_013287558.1"
                     /transl_table=11
                     /translation="MDISTREMSLTVGEAAERVGLTTYTLRWYEQEGLVGRVGRDSSGR
                     RRYTESDVNWLFLLTRLRRTGMPVRDMRRYAELARHGDSTLGARRALFEAHRARVLARM
                     AELEEDLKVLEHKIDAYRRAEEESG"
     misc_feature    complement(1761..1779)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.27"
                     /tool="antismash"
     misc_feature    complement(1762..1778)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     gene            1826..2548
                     /locus_tag="LF814_RS23630"
                     /old_locus_tag="LF814_23655"
     CDS             1826..2548
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287559.1"
                     /locus_tag="LF814_RS23630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23655"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_013287559.1"
                     /transl_table=11
                     /translation="MDDAVSVRELVVDRGGRRVLHGISCEVPRGTVTGLLGPSGSGKTT
                     LMRAVVGVQTVGSGTVDVLGRPAGSADLRRRVGYLTQAPSVYADLTVRENARYFAVLQG
                     RGRAEADRAVADVGLAEAADQLVGTLSGGQRSRASLACALVGEPELVILDEPTVGQDPV
                     LRADLWARFHAMAANGTTLLVSSHVMDEAARCDRLLLIREGRLVADDTPAAVRAATGTD
                     DLEEAFLRLIRDAEGEAR"
     gene            2545..3300
                     /locus_tag="LF814_RS23635"
                     /old_locus_tag="LF814_23660"
     CDS             2545..3300
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014389.1"
                     /locus_tag="LF814_RS23635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23660"
                     /product="ABC transporter permease"
                     /protein_id="WP_013287560.1"
                     /transl_table=11
                     /translation="MNGRILAATTGRILRQLRHDRRTVALLVVVPSVLLTLVYFMYVDQ
                     PAPPGGPSTFDRVALIMLGFFPFIIMFLVTSIAMLRERTTGTLERLLTTPLGKLDLLFG
                     YGIAFGLAGVLQSTVASVVAYRVFGLETAGSAWLVVLIAGVNAVLAVALGLFCSAFART
                     EFQAVQFMPVVVAPQLLLCGLFVPRGEMAGWLQAVSDVLPLSYAVEALQEVGAHAEPTG
                     TMWRDLAIVAGAAVAALVLAAATLRRRSG"
     gene            3297..3893
                     /locus_tag="LF814_RS23640"
                     /old_locus_tag="LF814_23665"
     CDS             3297..3893
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287561.1"
                     /locus_tag="LF814_RS23640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23665"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_013475814.1"
                     /transl_table=11
                     /translation="MNARRTGRRPGTPDTREAILAAAREAFAERGFDAASIRAIAAAAG
                     VDPALVHHYFGGKEELFRAATAFPADPGRLLPAVLAGGPDALGERMVRVFLEVWDSPTG
                     TAAVALLRSAVSNDWTARLLREFLVTQVLRRVLDQLDVDPAQRALRGGLVATQLAGLAM
                     MRYVLRLDAVATAEPATLVAAIGPTVQRYLTGDIT"
     gene            complement(3958..4689)
                     /locus_tag="LF814_RS23645"
                     /old_locus_tag="LF814_23670"
     CDS             complement(3958..4689)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785219.1"
                     /locus_tag="LF814_RS23645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23670"
                     /product="DUF2470 domain-containing protein"
                     /protein_id="WP_030271961.1"
                     /transl_table=11
                     /translation="MRPSPAEIVRTLVAGRLPALVHLARHPGPHQVRHAVDPDGRVLLL
                     VPVVSDLAAALVPPAGDTDVATVLDVLDLPPAAGAPSLGRAWVSGWAERLDGDEARDAA
                     VDFAATDPVGDLLDVGSRFHLHRFEVAEARWERAGRVRRVDPEAYAEAEPDPLHPVEAD
                     LLADLADHHAEQVGDYLRRRLDLPGDQTPQVVRIDRYGLLVAHGRPGATRRARLAFPRP
                     VADVAELSRLLHPMLCPRAAA"
     misc_feature    4704..4724
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.91"
                     /tool="antismash"
     misc_feature    4708..4726
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 32.19"
                     /tool="antismash"
     gene            4757..5365
                     /gene="rpsD"
                     /locus_tag="LF814_RS23650"
                     /old_locus_tag="LF814_23675"
     CDS             4757..5365
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015561.1"
                     /locus_tag="LF814_RS23650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23675"
                     /product="30S ribosomal protein S4"
                     /protein_id="WP_047892216.1"
                     /transl_table=11
                     /translation="MNHPRPKARLSRALGIPLTRKCVRYFERRPYPPGVHGRSRRTTSD
                     YQVRLLEKQRLRHQYNVSEAQLRRLFDEAARGAGKTGETLVALLERRLDAVVLRAGLAR
                     SIYQARQLVAHGHITVDGRKVDRPSYRLRPGQVVGVRERSRALPPFQLAAAGAHADAQP
                     RPYLSAQPAELRATLVREPARHEVPVVCDEQLVVEFYSR"
     gene            complement(5394..7184)
                     /locus_tag="LF814_RS23655"
                     /old_locus_tag="LF814_23680"
     CDS             complement(5394..7184)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475811.1"
                     /locus_tag="LF814_RS23655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23680"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_151012823.1"
                     /transl_table=11
                     /translation="MSATTAEADRNTEATESTWRTLRRGLALSPELRTGLAGTLALALV
                     YMVGRVAVPVAVQRGIDHGIVGGLDLNVISLTVAITAGVLVVTTACGYLMMRRLFTVSE
                     TALAGVRTRAFRHVHDLSMLHQQSERRGSLVSRVTSDVDQITQFLQWGGVILIVNLGQL
                     LVTTAVMLAYSWQLTLVVLVAFAPAVLVIRQLQRRLAGAYGLVRQRTGTLLGAIGESVV
                     GAPVIRAYGIAGRTARRLDTAIDGQRVAQQRAIRISIMGSSVGELAAGLALAGVVVVGV
                     SLGVDGTLTVGQLTAFLFLVTLFIQPVQIATEVLNEAQNAIAGWRRVLDVLDVSPDVAD
                     PGEQGRELPPGPLDARFAGVTFAYPGGPPVLHDVTLDIPAKSRVAVVGETGSGKTTFAK
                     LLTRLMDPTEGQVLLSGVDLRQVRFDSLRSRVVMVPQDGFLFDATVGENVRFARPDLTD
                     ERLTAAFAELGLSDWLDGLPSGLDTPVGERGEALSVGERQLVALARAYVADPDLLVLDE
                     ATSAVDPATEVRLQRTLDAVTRGRTTLAIAHRLSTAQAADEVIVVDRGRIVQRGPHEEL
                     VRDADSVYALLYASWLEQTR"
     gene            complement(7181..9049)
                     /locus_tag="LF814_RS23660"
                     /old_locus_tag="LF814_23685"
     CDS             complement(7181..9049)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020215714.1"
                     /locus_tag="LF814_RS23660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23685"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_225319626.1"
                     /transl_table=11
                     /translation="MASGTSRDVLGRGLRVLGRAIREQPRIFAVAVSGSVLFGLLVIAS
                     AYVVGGVVGDVVVPAVERGEVARGALALAATALFGISVLRVVGIFGRRLGAGYMQYRLQ
                     AAYRRRVTRRYLELPLAWHHRNSTGTLLSNANSDVEAAWYPIAPLPFAVGTLVMLVGAV
                     ASLFFTDWALALVGLAVFPALFALNVVYSRRMAPRQARAQRLRAEVSGIAHESFDGALV
                     VKTMGREAQETARFASRAGELRDALISVGRLRGVFDPMLETLPSLGTLAVLVVGALRLR
                     EGAITVTELVSVAFLFTVLAFPVRAIGWVLAELPRSVAGWDRVRRVLDATGEMPYGTTT
                     LDPATREPATLAFDDVHFAYEPAEAHLPGAQVLGEVTFTVPAGKTVALVGPTGAGKSTI
                     ASLAVRLVDPGAGRITLDGVDVRELTAASLAATAALVAQVPFVFDDTVRANIALDRAGI
                     GDDEVWAALRLAEADGFVAALPDGLDTMVGERGTSLSGGQRQRLTLARALAGRPRLLVL
                     DDATSAVDPRVEAAILAGLRAPADGGAPASILVVAYRRATIALADEVIYVEQGRVVARG
                     THTELLSTVPGYADLVTAYEQAEQEREQNRTYDEVTPLTSGLEVDR"
     gene            9243..9872
                     /locus_tag="LF814_RS23665"
                     /old_locus_tag="LF814_23690"
     CDS             9243..9872
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="LF814_RS23665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23690"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_047892214.1"
                     /transl_table=11
                     /translation="MPRYARAEREALADLMLEVGPDAPTVNEGWTTRDLAAHLLVRERR
                     PDAAGGILLPPLRGYGESVRRRIAAGPYADLIARVRRPPVWSPVSNPLTDELANGMEFF
                     IHHEDVRRARPGWHPRNLPAGQQAVLWKRVALLARMALRRFPAEVLVQAPGYGELRAGG
                     GGERLRLVGAPGELVLFLTGRQRVARVQVDGPADRAERLRTAELGL"
     misc_feature    complement(9928..9939)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.81"
                     /tool="antismash"
     gene            10001..10951
                     /locus_tag="LF814_RS23670"
                     /old_locus_tag="LF814_23695"
     CDS             10001..10951
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="LF814_RS23670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23695"
                     /product="terpene synthase"
                     /protein_id="WP_013475808.1"
                     /sec_met_domain="T1TS (E-value: 6.3e-73, bitscore: 245.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDFALSALHEPPFPSRRHPAVDQTAAESAAWVRDFGLVEDQAGR
                     RRLAGAHAAELAARACPEASPSGLRLLTDLVNWLFVVDDACDDDGLGATPTLLAPTLAA
                     LLAVLDRHGDPEAPAPADGGPIALALHDLCRRARDRGRPAHLLRLVSQLREYLLALLWE
                     AANRERRRVPGVAEYTQMRRHTGGVRPSFTVTDLARPSAPRADQRVAPALTVLDALATD
                     LICWCNDLFSYGKERGATPEAHNLVTTIAGETGQDESAALYAAADRFNKTLATYAERDA
                     ALSAVADKGMRAFLDTRRDWIRATYDWSRAASRYA"
     misc_feature    complement(11045..11060)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            11090..12916
                     /locus_tag="LF814_RS23675"
                     /old_locus_tag="LF814_23700"
     CDS             11090..12916
                     /NRPS_PKS="Domain: AMP-binding (14-471). E-value: 3.6e-88.
                     Score: 287.8. Matches aSDomain:
                     nrpspksdomains_LF814_RS23675_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="LF814_RS23675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23700"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_013475807.1"
                     /sec_met_domain="AMP-binding (E-value: 4.6e-86, bitscore:
                     287.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALDVPYRSVPDMFLKRVADSPDRHAFAHPAPDDSGPVWLTWEQV
                     GQRAKAIAAGLHGLGVGLENPVAILANTRLDWVLADFGIMCAGGATTTVYPTTEPEDAV
                     YIIADSGSKVLFAENQAQAAKIAGADLPALTHVVLFDGTPDPAAAVPQLTLAELEERGA
                     AALSAEPDLIDMLVAGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLR
                     VDDLQYLWLPLSHSFGKTLLCGATHVGLPTYVDGRVDKLVELLGVVQPTLMCGAPRVFE
                     KVYNKAVTTAQGAGGAKAKIFAWGVGVGKEKVALEQAGKPVPAGLRMKYALAEKLVFSK
                     LQARLGGRMRVLVSGAAPLSKEIATFFAAANLPISEGYGLTETSAGAFVNPPDGLKIGS
                     VGRAMGDLECRIDTDGEVLLRGKPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDADGY
                     LRITDRKKDLVKTSGGKYVAPSHIEGMFKAVCPYTSQAVVIGQARNYCTMLVTLDPDAI
                     KGWAAGTPLEGSDYTTIVTSPQAREMVEGYVAELNAKLNRWETIKKVTILPRDLTIEDG
                     EVTPSLKIKRRSVETNFASEIDKMYEGTLAEL"
     aSDomain        11132..12502
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LF814_RS23675_AMP-binding.1"
                     /evalue="3.60E-88"
                     /label="LF814_RS23675_AMP-binding.1"
                     /locus_tag="LF814_RS23675"
                     /protein_end="471"
                     /protein_start="14"
                     /score="287.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LKRVADSPDRHAFAHPAPDDSGPVWLTWEQVGQRAKAIAAGLHGL
                     GVGLENPVAILANTRLDWVLADFGIMCAGGATTTVYPTTEPEDAVYIIADSGSKVLFAE
                     NQAQAAKIAGADLPALTHVVLFDGTPDPAAAVPQLTLAELEERGAAALSAEPDLIDMLV
                     AGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLRVDDLQYLWLPLSHS
                     FGKTLLCGATHVGLPTYVDGRVDKLVELLGVVQPTLMCGAPRVFEKVYNKAVTTAQGAG
                     GAKAKIFAWGVGVGKEKVALEQAGKPVPAGLRMKYALAEKLVFSKLQARLGGRMRVLVS
                     GAAPLSKEIATFFAAANLPISEGYGLTETSAGAFVNPPDGLKIGSVGRAMGDLECRIDT
                     DGEVLLRGKPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDADGYLRITDRKKDLVKT"
     CDS_motif       11645..11704
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LF814_RS23675_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="LF814_RS23675"
                     /protein_end="205"
                     /protein_start="185"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     CDS_motif       12332..12406
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LF814_RS23675_0002"
                     /evalue="1.90E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="LF814_RS23675"
                     /protein_end="439"
                     /protein_start="414"
                     /score="23.4"
                     /tool="antismash"
                     /translation="GEVLLRGKPVMRGYHNLPEETAAAF"
     gene            complement(12980..14287)
                     /locus_tag="LF814_RS23680"
                     /old_locus_tag="LF814_23705"
     CDS             complement(12980..14287)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183503.1"
                     /locus_tag="LF814_RS23680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23705"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_191971135.1"
                     /transl_table=11
                     /translation="MGNGSGVRRSWTVRSAAPGSRTTRLELFYDLVFVFAFLNVTTLTA
                     SELTPANLYRFLLVLALLWWSWTGFARMGNFFRADQGVLPLVGFVTVAATFLLVLSEPS
                     AFEDLPGGLPGPLVFAGCYFVIRMAQLTVFGWVDRADPVRRRRLLLRAAFPAAATVLLV
                     IAGTVPTRLPQERFAIPLQLALWTLALLVEYVGGVTLARQWWVVVSAGHWAERHALIVL
                     VALGESIIALGFGPKHGLPLTGPVAVSALLGIVVVAALWWAYFDTLAFALEQALHHARD
                     EATRLRLARDVYTFMHLPMVAGIILYALGLKDLLAEAADPATPTWGLPLGDFWGAILFG
                     GVALHLLSLAGCWWIALREVHRPLLLAVVALVVVGPFVFRIPELIALGVLAVITGAGVT
                     WETRREDGLRRRVRRLALEEQIAAEAEQSRWRRGHL"
     gene            complement(14363..15814)
                     /locus_tag="LF814_RS23685"
                     /old_locus_tag="LF814_23710"
     CDS             complement(14363..15814)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (111-461). E-value:
                     4.1e-28. Score: 90.4. Matches aSDomain:
                     nrpspksdomains_LF814_RS23685_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014395.1"
                     /locus_tag="LF814_RS23685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23710"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_030271948.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.5e-26, bitscore:
                     90.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQVRGVQLARLLGQWHALPGRRRSPDYAALAGAVRGLLADGRL
                     PLGVRLPAERELAEALRISRTTVTAAYRELRESGHLASRRGAGSWTMLPGGHRVASTGL
                     WTPLDDRDMIDLGVAALSAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELREAVARAY
                     TERGLPTSPEQIMVTSGTQHALDLVLRLALSPGGAVLVESPTYPNALAALSARRARIAT
                     HGLSDEGWDAELLLGSLRQTRPKLAYVIPEFQNPTGHLMAADLRERLVGTAHAAGTDLV
                     VDESFVDLPLDDTTLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAPQVQRLAA
                     ARVGVDMASPVLDQLVAVHLLTEAPAIVAARRAQLVAQRDALVAALADRLPDWRVRVPS
                     GGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPADELVEAV
                     GRLAAVRYDLDRTSRPQWREPSVIA"
     aSDomain        complement(14432..15481)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LF814_RS23685_Aminotran_1_2.1"
                     /evalue="4.10E-28"
                     /label="LF814_RS23685_Aminotran_1_2.1"
                     /locus_tag="LF814_RS23685"
                     /protein_end="461"
                     /protein_start="111"
                     /score="90.4"
                     /tool="antismash"
                     /translation="DMIDLGVAALSAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELR
                     EAVARAYTERGLPTSPEQIMVTSGTQHALDLVLRLALSPGGAVLVESPTYPNALAALSA
                     RRARIATHGLSDEGWDAELLLGSLRQTRPKLAYVIPEFQNPTGHLMAADLRERLVGTAH
                     AAGTDLVVDESFVDLPLDDTTLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAP
                     QVQRLAAARVGVDMASPVLDQLVAVHLLTEAPAIVAARRAQLVAQRDALVAALADRLPD
                     WRVRVPSGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPA
                     DELVEAVGRL"
     gene            15874..16509
                     /locus_tag="LF814_RS23690"
                     /old_locus_tag="LF814_23715"
     CDS             15874..16509
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785228.1"
                     /locus_tag="LF814_RS23690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23715"
                     /product="membrane protein"
                     /protein_id="WP_013475804.1"
                     /transl_table=11
                     /translation="MAQLGNLRHRPVRRLTQLYAGLVLYGVSMALMIRSELGLDPWDVF
                     HQGLARQTGLSFGTVTIAVGALVLLLWIPLRQRPGLGTVSNVVVIGLVVDATLTVLPPG
                     EGMPARVALLVAGIVANGAATGLYLGAGLGPGPRDGLMTGFVARHPRFSVRLVRTVIEI
                     TVLALGWLLGGTVGLGTVAYALTIGPLAQFFIPVFALPARPAAGAYAT"
     gene            16626..17087
                     /locus_tag="LF814_RS23695"
                     /old_locus_tag="LF814_23720"
     CDS             16626..17087
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018804515.1"
                     /locus_tag="LF814_RS23695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23720"
                     /product="hypothetical protein"
                     /protein_id="WP_151012024.1"
                     /transl_table=11
                     /translation="MGENGWRWSDAWIFVALVIASGAGRHRRAAATRRPEGVRLADVLS
                     TADHLNQAIPERHEVEGAVRRLVGAGLVSVADGWFRVTPDGERLWRTRPSAGLGTTVDT
                     VQGVLTRRHPPAESEWHLDEDDHAAAVQEYVVRSIPMPRRSPEEHSGRQ"
     gene            complement(17096..17863)
                     /gene="hisF"
                     /locus_tag="LF814_RS23700"
                     /old_locus_tag="LF814_23725"
     CDS             complement(17096..17863)
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="LF814_RS23700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23725"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_013287573.1"
                     /transl_table=11
                     /translation="MTVAVRVIPCLDVDAGRVVKGVNFLDLRDAGDPVELAAAYDRAGA
                     DELTFLDVTASSSDRGTMLDVVRRTAESVFIPLTVGGGVRRVADVDTLLRAGADKVGVN
                     TAAIARPELIAEIADRFGRQVLVLSLDVRRAPDGTTPSGFEVTTHGGRRGTGLDAVEWA
                     ARGAELGAGEILLNSMDADGTKAGFDLPLIQAVREVVDVPVIASGGAGEVAHFPPAVGA
                     GADAVLAASVFHFGELTVGEVKDALRGAGHPVR"
     gene            complement(17950..18957)
                     /locus_tag="LF814_RS23705"
                     /old_locus_tag="LF814_23730"
     CDS             complement(17950..18957)
                     /NRPS_PKS="Domain: PKS_ER (26-333). E-value: 7.6e-21.
                     Score: 66.5. Matches aSDomain:
                     nrpspksdomains_LF814_RS23705_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018813683.1"
                     /locus_tag="LF814_RS23705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23730"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_013475802.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.7e-22, bitscore:
                     77.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEARVNREIHLASRPDGWPTPENFRLVTTEVPTPGPGQVVVRNR
                     FMSVDPYMRGRMNDVKSYVPPFALDAPLDGGAIGEVVAGEAGGVKPGDTVLHGLGWREY
                     ALVDAKGVRKVDPGLAPVTAYLGVLGMTGLTAYAGLLDVAAMKPGETVFVSGAAGAVGS
                     MVGQIAKLRGAGRVIGSAGSAAKVERLTALGFDAAFDYHDGPVYKQLKAAAPDGVDVYF
                     DNVGGDHLEAAIGAMNLHGRAAICGMIAQYNATEPPAAPRNLALVIGKRLTLRGFLVGD
                     HGHLREQFVQEVAGWLREGRLSYDETIVDGIEQAPEAFLGLLRGENLGKMLVRL"
     aSDomain        complement(17959..18879)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LF814_RS23705_PKS_ER.1"
                     /evalue="7.60E-21"
                     /label="LF814_RS23705_PKS_ER.1"
                     /locus_tag="LF814_RS23705"
                     /protein_end="333"
                     /protein_start="26"
                     /score="66.5"
                     /tool="antismash"
                     /translation="LVTTEVPTPGPGQVVVRNRFMSVDPYMRGRMNDVKSYVPPFALDA
                     PLDGGAIGEVVAGEAGGVKPGDTVLHGLGWREYALVDAKGVRKVDPGLAPVTAYLGVLG
                     MTGLTAYAGLLDVAAMKPGETVFVSGAAGAVGSMVGQIAKLRGAGRVIGSAGSAAKVER
                     LTALGFDAAFDYHDGPVYKQLKAAAPDGVDVYFDNVGGDHLEAAIGAMNLHGRAAICGM
                     IAQYNATEPPAAPRNLALVIGKRLTLRGFLVGDHGHLREQFVQEVAGWLREGRLSYDET
                     IVDGIEQAPEAFLGLLRGENLGKMLV"
     CDS_motif       complement(18469..18513)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LF814_RS23705_0001"
                     /evalue="9.10E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="LF814_RS23705"
                     /protein_end="163"
                     /protein_start="148"
                     /score="8.9"
                     /tool="antismash"
                     /translation="GETVFVSGAAGAVGS"
     gene            complement(19010..19435)
                     /locus_tag="LF814_RS23710"
                     /old_locus_tag="LF814_23735"
     CDS             complement(19010..19435)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287575.1"
                     /locus_tag="LF814_RS23710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23735"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_013287575.1"
                     /transl_table=11
                     /translation="MQVLYTASARATGDGRDGHVRTSDGTVELDLAVPKEMGGAGGAAN
                     PEQLFAAGYAACFHSALRVVARQAKADVSGSVVEAEVGIGPNGSGGYGLAVTLVVDLPA
                     VERAAAEQLVDAAHQVCPYSNATRGNVEVTRTVREAL"
     gene            complement(19437..19883)
                     /locus_tag="LF814_RS23715"
                     /old_locus_tag="LF814_23740"
     CDS             complement(19437..19883)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018789360.1"
                     /locus_tag="LF814_RS23715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23740"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_013287576.1"
                     /transl_table=11
                     /translation="MTDDLVLRRQVCFALYAASRALTDVYRPILDEHGLTYPQYLVLLV
                     LWEHDDDAPTVSELGAALRLDSGTLSPLLKRLEAAGLVVRTRSAADERRVEVGLTDRGR
                     ALRERMGDVPRQVASATGLTEAELVFLHGILTRVTETIHRQKEQ"
     gene            complement(19965..20390)
                     /locus_tag="LF814_RS23720"
                     /old_locus_tag="LF814_23745"
     CDS             complement(19965..20390)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785234.1"
                     /locus_tag="LF814_RS23720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LF814_23745"
                     /product="Rid family hydrolase"
                     /protein_id="WP_013287577.1"
                     /transl_table=11
                     /translation="MTAEPAERPVDAGVVTRLGSGGPWEALYGYSRVVRAGTLAITAGC
                     TSTVDGRVAHAGDAAAQTAQAIRIGLDALAEVGAGPGDVVRTRMYVTDRIYADEVGRAH
                     NAVFGPVRPVATMVVVAGLIDPDLLVEVELEAYLPER"
ORIGIN
        1 tgctccacgc tgaccagcag cgcgtcgccg tcacagtcga gcgccaccga gcggacgtac
       61 tggtggttgc ccgaggtggc gcccttgacc cagtactcgc cgcggctgcg cgaccagtag
      121 gtggcccggc cggtggtgag cgtgcggtgc agcgcctcgt cgtccatcca ggcgaccatc
      181 agcacctcgc ccgagtcgtg ggcgcggacc acggcggcga ccaggccgtc cggggtgcgg
      241 cggagcttgg ccgcgacggc cgggtcgagc cgggacggac gggccggtcc gggagcgggg
      301 gcgccggtca gcggcgcgtc aggggcgggc acggttgacc attctcccgc acgcggcccg
      361 ggcaccgccg acgtgtcccg ggaggcgggc gtcaccgtcc ccagcgcccg gcccaaccgg
      421 ccgaggtagc ggtccacccg gccgtcgacc agcgcctcgg ccaggtccgc cccgtgggtg
      481 gcggcgatct cgtcggcgta cgggcggatc agcggcagga tgccggtgac cagccgtccg
      541 gcggcggcgc cgacctcggc cgggtcaccg gcgcgcagcc cgaggcagag cagcatgtcg
      601 tggcggtagc cgggcggggc gaccggtagg tccagcgcgg cggtcagggc ggcccggcgg
      661 gacaccacgc gcacgctcgg gtttgcgggc cgcagcaccg aggggcagag ccgtgccagg
      721 tcggccgcgg cgagccggac cccgaccggg tcgtcggcca cacgggccgc ggcgaccttg
      781 cccagcgtcg cgatcaactc ctccaggcgc ggctcgtcgg cgggctggca gagcaccggc
      841 aggtcgatcc ggcggcgcca ttccggtacg gcccacagca gccgggcggg cgcggtgacc
      901 gggaggccga acgcccagtc ggcgggctga cccagccgcc gcacccacga gcggacgtca
      961 cgggcggcga ccgacacgtg cacgaggcga ccggcgaact cggtcaggta cgcccgccgg
     1021 gccgcgtacg gcatgccgcg gcgggacgcg gtctgccggg cgcccgtgcc ggcggtccgt
     1081 ccgtcgtcgg cgaccacgag cacgtccacg tccacgtcgc tgtgctcggt ggcggcccgc
     1141 cgggcatggc tgccgcgcag catgatcccg acgaccggcc ggtcggcggc ctgccgcagg
     1201 cgggcggccc agtcgtcgag gaacgcggtg tcgggcaact gcgctggacc cacggcgcca
     1261 tggtgccgaa atccgatctt caccgcaatg accgttgccg gacccactgt ccgccactgg
     1321 ggcgttcagc ctgattcctc ctcggcccgg cggtacgcgt cgatcttgtg ttcgaggacc
     1381 ttcaggtcct cctccagctc ggccatccgg gccagcacgc gggcccggtg cgcctcgaac
     1441 agcgcccgcc gcgcgccgag cgtgctgtcc ccgtgccggg ccagttcggc gtagcggcgc
     1501 atgtcgcgaa ccggcatccc ggtgcgccgc agccgggtga gcaggaacag ccagttgacg
     1561 tcggactcgg tgtagcgccg gcggcccgac gagtcccgcc cgacgcggcc caccaggccc
     1621 tcctgctcgt accagcgcag cgtgtaggtg gtcaggccga cccgttccgc cgcctcaccc
     1681 acggtgaggc tcatctcccg cgtgctgatg tccacgccct ccaggcttcc agttcgagcg
     1741 cactcgaagt caagtccctc attgccaggc gcacgcaatt cacctaccgt tgagttcaac
     1801 gggtgatgaa ttgatggagg cgagcatgga cgacgcggtg tcggtccgcg agctggtggt
     1861 cgaccggggc gggcggcggg tgctgcacgg catcagctgc gaggtgcccc ggggcacggt
     1921 gaccgggctg ctcgggccca gcggcagcgg caagaccacg ctgatgcgcg cggtggtcgg
     1981 cgtgcagacg gtcggctccg gcaccgtcga cgtgctcggc cgcccggccg gctcggccga
     2041 cctgcgccgc cgggtgggct acctgaccca ggccccgagc gtctacgccg acctgacggt
     2101 gcgggagaac gcccgctact tcgcggtgct ccagggccgg ggccgcgccg aggccgaccg
     2161 cgcggtggcc gacgtaggcc tcgccgaggc ggccgaccag ctcgtcggca cgctctccgg
     2221 cggccagcgc agccgcgcct cgctcgcctg cgcgctcgtc ggcgaacccg agctggtgat
     2281 cctcgacgaa ccgacagtcg gccaggaccc ggtgctgcgg gccgacctgt gggcccggtt
     2341 ccacgccatg gccgcgaacg gcaccacgct gctggtctcc agccacgtga tggacgaggc
     2401 cgcccgctgc gaccggctgc tgctgatccg cgagggacgg ctggtcgccg acgacacccc
     2461 ggccgcggtc cgcgccgcca ccgggaccga cgacctggag gaggcgttcc tgcgcctgat
     2521 ccgcgacgcc gagggagagg cgcgatgaac ggacggatcc tggccgccac caccgggcgc
     2581 atcctgcgcc agctccggca cgaccggcgg accgtggcgc tgctcgtggt ggtgccgtcg
     2641 gtgctgctca cgctcgtcta cttcatgtac gtcgaccagc ccgccccgcc cggcgggccc
     2701 agtacgttcg accgggtggc cctgatcatg ctgggcttct tcccgttcat catcatgttc
     2761 ctggtgacca gcatcgccat gctccgcgag cgcaccacgg gcacgctgga gcgcctgctc
     2821 accacgccgc tgggcaagct cgacctgctg ttcggctacg gcatcgcgtt cggcctggcc
     2881 ggggtgctcc agtccacagt cgcctcggtc gtcgcgtacc gggtgttcgg gctggagacc
     2941 gcgggcagcg cgtggctggt cgtgctgatc gccggggtga acgcggtgct cgcggtggcg
     3001 ctcgggctgt tctgctcggc gttcgcccgc accgagttcc aggcggtcca gttcatgccg
     3061 gtggtggtgg cgccgcaact gctgctgtgc ggcctgttcg tgccgcgcgg cgagatggcc
     3121 ggctggctcc aggcggtcag cgacgtgctg ccgctgtcgt acgcggtcga ggcgttgcag
     3181 gaggtcggcg cgcacgccga accgaccggg acgatgtggc gggacctggc gatcgtggcc
     3241 ggggcggcgg tggcggcgct ggtgctggcc gccgcgacgc tgcgccggcg cagcgggtga
     3301 acgcgcggcg caccgggcgg cggcccggca ctccggacac ccgcgaggcc atcctcgccg
     3361 cggcgcggga ggcgttcgcc gaacgcggct tcgacgccgc gtcgatccgg gccatcgccg
     3421 ccgcggccgg cgtggacccg gcgctcgtgc accactactt cggcggcaag gaggagctgt
     3481 tccgggccgc gacggcgttc ccggccgacc cgggacggct gctgccggcg gtgctcgccg
     3541 gcggcccgga cgcgctcggc gagcggatgg tccgggtgtt cctggaggtc tgggactccc
     3601 ccaccggcac ggcggcggtg gcgctgctgc ggtcggcggt gagcaacgac tggaccgcgc
     3661 gcctgctgcg cgagttcctg gtcacgcagg tgctgcgccg ggtgctcgac cagctcgacg
     3721 tcgacccggc gcagcgcgcg ctgcgcggcg ggctggtcgc cacgcagctc gccgggctgg
     3781 ccatgatgcg gtacgtgctc cgcctcgacg cggtcgccac ggccgagccg gcgacgctgg
     3841 tggcagccat cggcccgacg gtccagcggt acctcaccgg cgacatcacc tgagccggcc
     3901 cggccgacgg ctccgacggc cgggaccgcg ctgctcgggc agccgggccg gctgtgctca
     3961 ggcggcggcc cgggggcaga gcatcgggtg cagcaggcgg gacagctccg ccacgtcggc
     4021 gacgggccgg gggaaggcca gccgggcccg ccgggtcgcg ccgggccgcc cgtgcgcgac
     4081 cagcagcccg tacctgtcga tccggaccac ctgcggcgtc tggtcgccgg gcaggtccag
     4141 ccgccgccgc aggtagtcgc cgacctgctc ggcgtggtgg tcggccaggt cggcgaggag
     4201 gtcggcctcg accgggtgca gcgggtccgg ctcggcctcc gcgtacgcct ccgggtcgac
     4261 ccggcgcacg cgcccggcgc gttcccagcg ggcctcggcc acctcgaagc ggtgcaggtg
     4321 gaagcggctg cccacgtcga gcaggtcgcc gacagggtcg gtggcggcga agtcgactgc
     4381 cgcgtcgcgc gcctcgtccc cgtccagccg ctcggcccag ccggacaccc aggcccggcc
     4441 gagcgagggc gccccggccg ccggtggcag gtcgagcacg tcgagcacgg tggccacgtc
     4501 ggtgtcgccc gccggcggca cgagcgccgc ggcgaggtca ctgaccacgg gtacgagcag
     4561 cagcacccgc ccgtcggggt cgacggcgtg ccggacctgg tgcgggccgg ggtgccgggc
     4621 caggtggacg agggcgggca accggcccgc gacaagggtt cgcacgatct ccgccgggct
     4681 gggccgcatg atcccgacct cctcaacata ggttaggctt acctaagaag caggctagac
     4741 gatcggagac gtcgacgtga accacccccg gcccaaggcc cggctctccc gcgccctcgg
     4801 tatcccgctc acccgcaagt gcgtgcggta cttcgagcgg cgcccctatc ccccgggtgt
     4861 gcacggccgg tcccgccgca ccacctccga ctaccaggtg cggctgctgg agaagcagcg
     4921 gctgcgccac cagtacaacg tcagcgaggc ccagctgcgc cgcctgttcg acgaggccgc
     4981 ccggggcgcc ggcaagaccg gcgagacgct cgtcgcgctg ctggagcgac gcctcgacgc
     5041 ggtggtgctg cgggccgggc tggcgcgcag catctaccag gcccgccagc tcgtcgcgca
     5101 cggccacatc accgtcgacg ggcgcaaggt cgaccggccg tcgtaccggc tgcggcccgg
     5161 ccaggtggtc ggcgtacgcg agcgcagccg cgcgctgccg ccgttccagc tcgccgccgc
     5221 cggcgcgcac gccgacgcgc agccccggcc gtacctgtcg gcgcagccgg ccgagctgcg
     5281 cgccacgctg gtgcgcgaac cggcccggca cgaggtgccg gtggtgtgcg acgagcagct
     5341 ggtggtggag ttctactccc gctgaccgcc gctcccgagc agacccgcca aggtcagcgg
     5401 gtctgctcca gccaggacgc gtacagcagg gcgtacaccg agtcggcgtc gcggaccagt
     5461 tcctcgtgcg ggccgcgctg cacgatccgg ccccggtcca ccacgatcac ctcgtccgcc
     5521 gcctgcgcgg tggacagccg gtgcgcgatg gcgagcgtgg tccggccccg ggtcaccgcg
     5581 tcgagcgtcc gttgcaggcg gacctcggtg gccgggtcga cagcgctcgt cgcctcgtcc
     5641 agcaccagca ggtccgggtc cgcgacgtac gcccgggcca gcgccacgag ctgccgctcg
     5701 ccgacgctca acgcctcccc gcgctcaccg accggtgtgt ccagcccgga cggcaggccg
     5761 tccagccagt cggagaggcc cagctcggcg aaggcggcgg tgagtcgctc gtcggtcagg
     5821 tcggggcggg cgaagcggac gttctccccg accgtggcgt cgaacaggaa gccgtcctgc
     5881 ggcaccatca ccacccggga gcgcagcgag tcgaagcgca cctgccgcag gtcgaccccg
     5941 gagagcagga cctgcccctc ggtggggtcc atcagccggg tgagcagctt ggcgaaggtg
     6001 gtcttgccgc ttccggtctc gcccaccacc gccacccggc tcttggccgg gatgtccagc
     6061 gtcacgtcgt gcagcaccgg gggcccgccc ggataggcga acgtgacacc ggcgaagcgg
     6121 gcgtccagcg gcccgggtgg cagctcccgc ccctgctcgc ccgggtcggc gacgtccggg
     6181 gagacgtcca gcacgtccag cacccggcgc cagccggcga tcgcgttctg cgcctcgttg
     6241 agcacctcgg tggcgatctg caccggctgg atgaacagcg tgaccaggaa caggaacgcg
     6301 gtgagctggc cgaccgtcag cgtgccgtcg acgcccaggc tgaccccgac caccaccacg
     6361 cccgccagcg ccaggccggc ggccagctcc cccaccgagc tgcccatgat gctgatccgg
     6421 atcgcccgct gctgggccac ccgctgcccg tcgatggccg tgtccagccg ccgcgcggtg
     6481 cgcccggcga tgccgtacgc ccggatcacc ggcgcgccca ccacgctctc gccgatcgcg
     6541 ccgagcagcg tgccggtgcg ctgccgcacc agcccgtacg caccggcgag gcggcgctgc
     6601 aactgccgga tcaccagcac cgcgggcgcg aacgcgacga gcaccacgag cgtcagctgc
     6661 caggagtacg cgagcatcac ggcggtggtc accagcaact ggcccaggtt gacgatgagg
     6721 atcacgccgc cccactggag gaactgggtg atctggtcga cgtcgctggt gacccgggag
     6781 acgagcgacc cgcgccgctc ggactgctgg tgcagcatgg acaggtcgtg cacgtgccgg
     6841 aacgcccggg tgcgcacccc ggccagcgcg gtctcgctca ccgtgaacaa ccggcgcatc
     6901 atcaggtacc cgcaggcggt ggtgaccacc agcacgccgg cggtgatcgc cacggtcagc
     6961 gagatgacgt tcaggtcgag gccgccgacg atgccgtggt cgatgccgcg ctgcaccgcc
     7021 accggcacgg ccacccggcc gaccatgtag accagcgcca gcgccagcgt gccggcgagg
     7081 ccggtgcgca gctccgggga gagcgccagc ccgcgccgca gcgtccgcca ggtcgactcg
     7141 gtggcctcgg tgttccggtc cgcctccgcc gtggtcgcgc tcaccggtcc acctccaggc
     7201 ccgaggtcaa cggcgtgacc tcgtcgtacg tccgattctg ctcgcgttcc tgctcggcct
     7261 gctcgtacgc ggtgacgagg tcggcgtagc cgggcacggt ggacagcagc tcggtgtggg
     7321 tgccgcgggc gaccacccgg ccctgctcca cgtagatcac ctcgtcggcg agcgcgatgg
     7381 tggcccggcg gtacgccacc accaggatcg acgccggggc gccgccgtcc gcgggcgcgc
     7441 gcagcccggc caggatggcc gcctcgaccc gcgggtcgac agcgctcgtg gcgtcgtcga
     7501 gcaccagcag ccggggtcgc ccggcgagcg cccgggccag cgtcagccgc tggcgctgac
     7561 cgccggacag cgacgtgccc cgctcgccga ccatggtgtc cagcccgtcc ggcagcgcgg
     7621 ccacgaagcc gtccgcctcg gccagccgca gcgccgccca gacctcgtcg tcgccgatgc
     7681 cggcccggtc gagagcgatg ttggcccgga ccgtgtcgtc gaagacgaac ggcacctgcg
     7741 ccacgagcgc cgccgtggcc gccagcgagg cggcggtcag ctcccgcacg tccacgccgt
     7801 ccagcgtgat ccggccggcg cccgggtcca ccaggcgcac ggcgagcgac gcgatcgtcg
     7861 acttgcccgc gccggtgggg ccgaccaggg cgaccgtctt cccggccggg actgtgaacg
     7921 tcacctcgcc gagcacctgt gcgccgggca ggtgcgcctc ggccggctcg tacgcgaagt
     7981 gcacgtcgtc gaaggcgagc gtggccggct cgcgggtggc cgggtcgagc gtcgtcgtgc
     8041 cgtacggcat ctcgccggtc gcgtcgagca cccggcggac ccggtcccac ccggcgacgc
     8101 tgcgcggcag ctcggccagc acccagccga tggcgcgtac cgggaaggcc agcacggtga
     8161 acaggaacgc gacgctgacc agctcggtca cggtgatcgc gccctcccgc agccgcagcg
     8221 cgccgaccac cagcacggcg agcgtgccga ggctgggcag cgtctccagc atcgggtcga
     8281 acacgccacg cagccggccg accgagatca gcgcgtcgcg cagctcaccg gcgcgggagg
     8341 cgaagcgggc cgtctcctgg gcctcgcggc ccatcgtctt gaccacgagc gcgccgtcga
     8401 agctctcgtg cgcgatgccg ctgacctcgg cccgcagccg ctgcgcccgg gcctgccggg
     8461 gcgccatccg gcgggagtag accacgttga gcgcgaacag cgccgggaac acggcgaggc
     8521 cgaccagggc cagcgcccag tcggtgaaga acagtgaggc caccgcgccg acgagcatca
     8581 ccagcgtgcc gaccgcgaac ggcagcggcg cgatcgggta ccaggccgcc tccacgtcgg
     8641 agttggcgtt cgacagcagc gtgccggtgg agttgcggtg gtgccaggcc agcggcagtt
     8701 ccaggtagcg gcgggtgacc cggcggcggt aggcggcctg gagccggtac tgcatgtaac
     8761 cggcgccgag ccggcggccg aagatgccga cgacacgcag cacgctgatg ccgaacagcg
     8821 ccgtcgcggc gagcgccagc gccccgcggg ccacctcgcc gcgctccacg gccggcacga
     8881 cgacgtcgcc gaccaccccg ccgaccacgt acgcgctggc gatcaccagg aggccgaaca
     8941 gcacgctgcc gctgaccgcg accgcgaaga tccgtggctg ttcccggatg gcccggccga
     9001 gcacccgtag ccctctgccg agcacgtccc gacttgtccc gctcgccacg ctctcccccg
     9061 ccgtaagccg cagttttctc ccccatcctt accgctcgcc gcccgtcccg ccgacccggc
     9121 cgggatatgt ccgccgtcac gttcccgccg gagctgggcc gacggcgacc ggaggcggtc
     9181 cggcggcgtg gtcgcgccgg gcgtggcgcg ccgatcggcc gggaccggcc tacgatcggg
     9241 ccatgccgcg gtacgcccga gcggagcgcg aggcgctcgc cgacctgatg ctggaagtgg
     9301 gaccggacgc accgactgtg aacgaggggt ggaccactcg tgacctggcg gcgcacctgc
     9361 tggtgcggga gcgccggccg gacgcggcgg gcgggatcct gctgccgccg ctgcgcggct
     9421 acggcgagtc ggtccgtcgg cggatcgccg ccgggccgta cgccgacctg atcgcccggg
     9481 tacgccgtcc cccggtgtgg agcccggtga gcaacccgct caccgacgag ctggcgaacg
     9541 ggatggagtt cttcatccac cacgaggacg tgcggcgcgc ccgtccgggc tggcatccgc
     9601 gcaacctgcc ggccgggcag caggcggtgc tgtggaagcg ggtcgcgctg ctggcccgga
     9661 tggcgctgcg gcggttcccg gccgaggtgc tggtgcaggc gccgggctac ggcgagctgc
     9721 gggccggcgg cggcggcgaa cggctgcggc tggtcggtgc gccgggcgag ctggtcctgt
     9781 tcctcaccgg acggcagcgg gtggcccggg tccaggtgga cggtccggcc gaccgcgccg
     9841 agcgcctgcg caccgccgag ctgggactct gaccgagggt gtgtagccga tcgctcgctg
     9901 actgtggaaa gtggacggac cggcttcgat aacggttacg tcctcccgta cgctcctgcg
     9961 caccggcccg accccgcggg gcggcggaca ggggacgacg atgcgcgact tcgccctctc
    10021 ggcactgcac gagccaccct ttccctcccg gcgccacccc gccgtcgacc agacggccgc
    10081 ggagagcgcg gcctgggtac gcgacttcgg cctggtggag gaccaggccg ggcgccggcg
    10141 gctggccggg gcgcacgccg cggagctggc cgctcgcgcc tgccccgagg cgtcgccgtc
    10201 cggattgcgc ctgctcaccg acctggtcaa ctggctgttc gtggtggacg acgcctgcga
    10261 cgacgacggg ctcggcgcga cgcccacgct gctggcgccc acgctggccg cgctgctggc
    10321 ggtgctcgac cggcacggcg acccggaggc gcccgcaccg gccgacggcg ggccgatcgc
    10381 cctggcgctg cacgacctgt gccggcgggc ccgcgaccgg ggccggccgg cccacctgct
    10441 gcgcctggtc agccagttgc gggagtacct gctggcgctg ctctgggagg ccgccaaccg
    10501 ggaacgccgg cgggtgccgg gggtggccga gtacacgcag atgcgccgcc acaccggcgg
    10561 ggtgcgcccc agtttcactg tgaccgacct ggcccgcccg tccgcgcccc gcgccgacca
    10621 gcgggtcgcg ccggcgctca ccgtgctgga cgccctcgcc accgacctga tctgctggtg
    10681 caacgacctg ttctcctacg gcaaggagcg gggcgccacc ccggaggcgc acaacctggt
    10741 caccacgatc gcgggcgaga ccgggcagga cgagtcggcg gcgctgtacg cggcggccga
    10801 ccggttcaac aagaccctcg ccacgtacgc ggagcgggac gcggcgctga gcgccgtggc
    10861 cgataagggg atgcgggcgt tcctggacac ccgccgggac tggatccggg ccacctacga
    10921 ctggtcccgc gcggccagcc ggtacgcctg accggttcca gcaggcggga ccgctgacga
    10981 ctcggccgat cggggctagc cgctggccgg gtgcacgcaa tacccttcgg taaccgcaga
    11041 ccggcgtgac ccccgtcacg tccctccacc cctgaaggcg gctacagcga tggctctcga
    11101 tgtaccgtac cgttccgtac cggacatgtt cctcaagcgt gtggcggact cccccgaccg
    11161 gcacgccttc gcccaccccg cccccgacga ctcgggcccg gtctggctga cgtgggagca
    11221 ggtcgggcag cgcgccaagg cgatcgccgc cgggttgcac gggctcggtg tcggcctgga
    11281 gaacccggtc gcgatcctgg ccaacacgcg cctggactgg gtgctcgccg acttcggcat
    11341 catgtgcgcc ggtggtgcca ccaccaccgt ctaccccacc accgagcccg aggacgcggt
    11401 ctacatcatc gccgactccg gctcgaaggt gctgttcgcg gagaaccagg cccaggcggc
    11461 gaagatcgcc ggggcggacc tgcccgcgct gacccacgtg gtgctcttcg acggcacgcc
    11521 cgacccggcg gcggccgtcc cgcagctcac cctggccgag ctggaggagc ggggcgccgc
    11581 cgcgctgagc gcggagccgg acctgatcga catgctcgtc gccggcatcg gcccggacca
    11641 cctcgcaacg ctgatctaca cctcgggcac caccggccgc ccgaagggcg tggagctgct
    11701 gcacggcggc tggtgctggg agggcgtggc gcaggccgag ctgggcctgc tgcgcgtcga
    11761 cgacctgcaa tacctgtggc tgccgctgtc gcactcgttc ggcaagacgc tgctctgcgg
    11821 cgccacccac gtcggcctgc ccacgtacgt cgacggccgg gtggacaagc tcgtcgaact
    11881 gctcggcgtg gtgcagccga cgctcatgtg cggcgcgccc cgggtcttcg agaaggtcta
    11941 caacaaggcc gtcaccaccg cccagggcgc cggcggcgcc aaggccaaga tcttcgcctg
    12001 gggcgtcggg gtcggcaagg agaaggtcgc gctggagcag gccggcaagc cggtcccggc
    12061 cgggctgcgg atgaagtacg cgctggccga gaagctcgtg ttcagcaagc tccaggcccg
    12121 gctcggcggc cggatgcggg tgctggtctc cggcgcggcg ccgctgagca aggagatcgc
    12181 caccttcttc gccgccgcca acctgcccat ctccgagggc tacggcctga ccgagaccag
    12241 cgcgggcgcg ttcgtgaacc cgcccgacgg gctgaagatc ggcagcgtgg gccgggccat
    12301 gggcgacctg gagtgccgga tcgacaccga cggcgaggtc ctgttgcgcg gcaagccggt
    12361 catgcgcggc taccacaacc tgcccgagga gaccgccgcc gcgttcaccg aggacggctt
    12421 cttccgcacc ggtgacatcg gcacgctcga cgccgacggc tacctgcgca tcaccgaccg
    12481 gaagaaggac ctggtcaaga cgtccggcgg caagtacgtc gcgccgtcgc acatcgaggg
    12541 catgttcaag gcggtgtgcc cgtacacctc acaggccgtg gtgatcgggc aggcgcgcaa
    12601 ctactgcacg atgctcgtca cgctggaccc ggacgcgatc aagggctggg ccgccggcac
    12661 cccgctggag ggcagcgact acaccacgat cgtcacctcg ccgcaggcac gggagatggt
    12721 cgaggggtac gtggccgagc tgaacgccaa gctcaaccgc tgggagacga tcaagaaggt
    12781 gacgatcctc ccccgcgacc tgaccatcga ggacggcgag gtcacgccgt cgctgaagat
    12841 caagcgccgc agcgtggaga cgaacttcgc ctccgagatc gacaagatgt acgagggcac
    12901 gctcgccgag ctgtagcccg taccgccaca cggtcgcgcc ggccgtgccc caccgtcccg
    12961 gggcacggcc gcacgccgtt cacaggtgcc cccgccgcca ccggctctgt tcggcctcgg
    13021 cggcgatctg ctcctccagc gcgagccggc gtacgcggcg ccggaggccg tcctcgcggc
    13081 gcgtctccca ggtgacgccg gcgccggtga tcaccgcgag cacgccgagc gcgatcagct
    13141 ccgggatacg gaagacgaac gggccgacca ccaccagcgc caccaccgcg agcagcagcg
    13201 gccggtgcac ctcgcgcagc gcgatccacc agcacccggc gaggctgagc aggtgcaacg
    13261 ccaccccgcc gaacaggatc gcgccccaga agtcgcccag cggcagcccc caggtgggcg
    13321 tggccgggtc ggcggcctcg gccagcagat ccttgaggcc gagcgcgtag aggatgatcc
    13381 cggcgaccat cggcaggtgc atgaacgtgt agacgtccct ggccaaccgg agccgggtgg
    13441 cctcgtcccg ggcgtggtgc agcgcctgtt ccagcgcgaa cgcgagcgtg tcgaagtacg
    13501 cccaccacag cgccgcgacg accacgatgc cgagcagcgc cgacaccgcc accggcccgg
    13561 tcagcggcag cccgtgcttc gggccgaagc cgagggcgat gatcgactca ccgagcgcga
    13621 ccagcacgat cagcgcgtgc cgttcggccc agtgcccggc cgagaccacc acccaccact
    13681 gacgggcgag cgtcaccccg ccgacgtact cgacgagcag cgccagcgtc cagagcgcca
    13741 gttgcagcgg gatcgcgaac cgctcctgcg gcagccgcgt cggcacggtt ccggcgatga
    13801 ccagcagcac cgtggcggcg gccgggaacg cggcgcgcag cagcagccgg cgacgccgga
    13861 ccgggtcggc gcggtccacc cagccgaaga cggtgagctg ggccatccgg atcacgaagt
    13921 agcagccggc gaagaccagc gggccgggca gcccgccggg gaggtcctcg aacgcgctgg
    13981 gctcgctgag caccagcagg aatgtcgccg ccaccgtgac gaagccgacc agcggcagca
    14041 caccctggtc ggcgcggaag aagttgccca tccgggcgaa gccggtccac gaccaccaga
    14101 gcagcgccag caccagcagg aagcggtaga ggttggccgg cgtgagttcc gaggcggtga
    14161 gcgtggtgac gttcaggaac gcgaagacga agaccaggtc gtagaagagt tccagccggg
    14221 tggtgcggga acccggggcg gcggaccgca cggtccacga ccgccggaca ccgctcccgt
    14281 tccccactgg ggcagtgtgc gggcaccgtc cgtcccgcag ccgtcgttcg acgcattcac
    14341 caccggaacg ggcaccgcgc gctcaggcga tgacgctcgg ctcccgccac tgcgggcggc
    14401 tggtgcggtc caggtcgtag cggaccgccg cgaggcgccc gacagcctcc accagctcgt
    14461 cggcgggcag cgtgaagggc agccgcagga agcgctccag cgtcccgtcc aggccgaacc
    14521 gcggtccggg cgccagccgt acgccgacct cctcggccgc gcgggccagc gcgctggaga
    14581 tcgggccgtc cagctcggcc cagagcgtga caccgccgct cggcacgcgt acgcgccagt
    14641 cgggcagccg gtcggcgagc gcggcgacca gggcgtcccg ctgggcgacg agctgggccc
    14701 ggcgggccgc cacgatggcc ggcgcctcgg tgagcaggtg cacggcgacg agctggtcca
    14761 gcaccgggct ggccatgtcc accccgaccc gggccgcggc cagccgctgc acctggggcg
    14821 cggaggcgcg gacccagccg atccgcagcc cgccccagta gggcttgctc atgccgccga
    14881 tgctgatcac ccgggagtgc ctgtcgaaga cggccaccgg cggcggcagc gtggtgtcgt
    14941 ccagcggcag gtcgacgaag gactcgtcga ccaccaggtc ggtgccggcc gcgtgggccg
    15001 tgccgaccag ccgctcgcgc aggtcggcgg ccatgaggtg gccggtcggg ttctggaact
    15061 cggggatcac gtacgcgagc ttcggccggg tctgccggag gctgccgagc agaagttcgg
    15121 cgtcccagcc ctcgtcggac aggccgtgcg tggcgatccg ggcccgccgg gcggacagcg
    15181 cggccagcgc gttggggtag gtgggcgact cgacgagcac ggcgccgccg ggcgacaggg
    15241 ccagccgcag caccaggtcc agcgcgtgct gggtgccgct ggtgaccatg atctgctccg
    15301 ggctggtggg cagaccgcgt tcggtgtagg cgcgggccac cgcctcgcgc agctcgatga
    15361 tgccggtcgg gtggtagccg gcgccgccga ggtagcgggg caggtcctcg gccgcggccc
    15421 gggcggcggg gacgagctgc gggggcgcgg acagcgcggc cacgccgagg tcgatcatgt
    15481 cgcggtcgtc gagcggcgtc cacaggccgg tgctggccac ccggtgcccg ccgggcagca
    15541 tggtccagct ccccgcgccc cggcggctgg ccaggtggcc gctctcccgc agttcccggt
    15601 acgcggcggt gacagtggtc cggctgatcc gcagcgcctc ggccagctcc cgctcggccg
    15661 gcaggcgtac cccgagaggc agccgcccgt cggcgagcaa gccgcggacg gcgccggcga
    15721 gcgcggcgta gtcggggctg cgccgacggc ccggcagggc atgccactgg ccgaggagtc
    15781 gcgccaattg gacgccgcgc acctggctgg tcatggccac acctccgaaa ttggcaccct
    15841 tgagagccgc gattggcccc tagggtggca tgcatggcac agcttggcaa tctccggcac
    15901 cgaccggtgc ggcggctcac ccagctctac gccgggctgg tcctctacgg cgtgagcatg
    15961 gcgctgatga tccggtcgga gctggggctg gacccgtggg acgtgttcca ccaggggctc
    16021 gcccggcaga ccggcctgtc cttcggcacc gtcaccatcg ccgtcggcgc cctcgtgctg
    16081 ctgctctgga tcccgctgcg gcagcggccc ggcctcggca cggtcagcaa cgtcgtggtg
    16141 atcggactgg tcgtcgacgc caccctaacc gtgctgccgc ccggagaggg catgccggca
    16201 cgcgtcgcgc tgctcgtcgc cgggatcgtc gccaacggcg ccgccaccgg cctctacctc
    16261 ggcgccgggc tcggccccgg cccgcgcgac gggctgatga ccggcttcgt cgcccgccac
    16321 ccccggttct cggtccggct ggtccgcacc gtcatcgaga tcaccgtgct ggcgctcggc
    16381 tggctgctcg gcggcaccgt cggcctcggc acggtggcgt acgcgctcac catcggcccg
    16441 ctggcccagt tcttcatccc ggtcttcgcg ctgcccgcac ggccggcggc cggtgcgtac
    16501 gctacgtgac cgcagccggg ccgaccgcca cggcccggta ccgaccgcaa cgcgctgagc
    16561 tgcgacgacg cacaaccggg aaaccaggtg tttcctccgc cgtcgcggcc gggcatcatt
    16621 cctgcatggg ggagaacgga tggcgttgga gcgacgcctg gatcttcgtc gcgcttgtca
    16681 tcgccagtgg cgccggccgg caccggcggg ccgccgcgac acgccgcccc gaaggcgtac
    16741 ggctggccga cgtcctctcc acagccgacc acctcaacca ggccatcccg gagcggcacg
    16801 aggtggaggg cgcggtccgg cggctcgtcg gcgcgggcct ggtcagcgtg gccgacggct
    16861 ggttccgggt caccccggac ggtgagcggc tctggcgcac ccggcccagc gccggtctcg
    16921 gcaccacagt ggacacggtg cagggcgtgc tgacccggcg gcacccgccc gccgagtccg
    16981 agtggcacct cgacgaggac gaccacgccg ccgccgtgca ggagtacgtg gtccggtcga
    17041 tcccgatgcc gcgccgctcc cccgaggagc actccggccg gcagtgaccg ccgcctcagc
    17101 gcaccgggtg gcccgcgccg cgcagcgcgt ccttgacctc gccgactgtg agttcgccga
    17161 agtggaagac gctcgccgcg agcaccgcgt ccgccccggc gccgacggcc ggcgggaagt
    17221 gggccacctc gcccgcgccg ccgctggcga tcaccggcac gtcgaccacc tcgcggaccg
    17281 cctggatcag cggcaggtcg aacccggcct tggtgccgtc ggcgtccatc gagttgagca
    17341 ggatctcgcc cgcgcccagc tcggcgccgc gcgccgccca ctcgaccgcg tccagcccgg
    17401 tgccccgccg gccgccgtgc gtggtcacct cgaaaccgct cggcgtcgtg ccgtccggtg
    17461 cgcggcgcac gtccagcgag agcaccagga cctgccggcc gaaccggtcg gcgatctcgg
    17521 cgatcagctc cggccgggcg atggccgcgg tgttcacgcc gaccttgtcc gcaccggcgc
    17581 gcagcaacgt gtcgacgtcg gcgacccggc ggacaccgcc gcccactgtc agcgggatga
    17641 agaccgactc ggcggtgcgc cgcaccacgt cgagcatggt gccccggtcg ctggacgagg
    17701 cggtgacgtc gaggaaggtc agctcgtccg cgccggcccg gtcgtacgcc gccgccagct
    17761 ccaccgggtc gccggcgtca cgcaggtcga ggaagttgac ccccttgacc acgcgcccgg
    17821 cgtccacgtc cagacacggg atgacccgta ccgccaccgt catgccccga gcctaacgaa
    17881 cgcgcgggcg gtggtgaccc gccggtgagg ccggtcacca ccgcccgcgg tggagtgcgt
    17941 tcgcgccggt cagagacgga ccagcatctt gccgaggttc tcgccgcgca gcaggccgag
    18001 gaacgcctcg ggggcctgct cgatgccgtc gacgatcgtc tcgtcgtacg acagccggcc
    18061 ctcccgcagc cagcccgcca cctcctgcac gaactgctcc cgcaggtgac cgtggtcacc
    18121 gacgaggaag ccgcgcagcg tcagccgctt gccgatcacc agcgccaggt tgcgcggcgc
    18181 ggcgggcggc tcggtggcgt tgtactgcgc gatcatgccg cagatggcgg cccggccgtg
    18241 caggttcatc gccccgatcg cggcctccag gtgatcgccg ccgacgttgt cgaagtacac
    18301 gtcgacgccg tccggggcgg ctgccttgag ctgcttgtac accgggccgt cgtggtagtc
    18361 gaaggcggcg tcgaagccga gcgcggtgag tcgttccacc ttcgccgcgg aaccggcgct
    18421 gccgatcacc cggccggcgc cgcgcagctt cgcgatctgg cccaccatgc tgcccaccgc
    18481 gccggccgcg ccggagacga acacggtctc ccccggcttc atcgccgcca cgtcgagcag
    18541 cccggcgtac gcggtcagcc cggtcatgcc gagcacgccc aggtacgcgg tgaccggcgc
    18601 gaggccggga tcgaccttgc gcacgccctt ggcgtccacc aacgcgtact cgcgccagcc
    18661 gagcccgtgc agcaccgtgt cgccgggctt gacgccaccg gcctcgccgg ccaccacctc
    18721 accgatggcg ccgccgtcca gcggggcgtc gagcgcgaac ggcggcacgt acgacttgac
    18781 gtcgttcatc cgcccgcgca tgtacgggtc gacggacatg aaccggttcc ggaccactac
    18841 ctgtcccggg cccggcgtcg gcacctcggt ggtgaccagc cggaagttct ccggcgtcgg
    18901 ccagccgtcc ggccgggacg ccagatggat ctcccggttg acgcgcgcct cactcatcgg
    18961 gcctcctcgg ttcgcactgc ggggctccgc tgcgctgcac tcctcgtgct cacagggcct
    19021 cgcggaccgt gcgggtcacc tcgacgttcc cacgggtcgc gttggagtag gggcagacct
    19081 ggtgggccgc gtcgacgagc tgctcggcgg ccgcgcgctc gacagcgggc aggtccacca
    19141 cgagcgtcac ggccaggccg taaccgccgc tgccgttcgg gccgatgccc acctcggcct
    19201 cgacgacgga gccggagacg tccgccttgg cctgacgggc caccacgcgc agcgcggagt
    19261 ggaagcaggc cgcgtagccg gccgcgaaga gctgctccgg gttggccgcg ccgccggcgc
    19321 cacccatctc cttcggtacg gcgaggtcca gctcgaccgt gccgtcggag gtccggacgt
    19381 gaccgtcgcg gccgtcgccg gtggcgcggg cggaggcggt gtagagcacc tgcatgtcac
    19441 tgctccttct gtcggtggat cgtctcggtg acccgggtga ggatgccgtg gaggaagacc
    19501 agctcggcct cggtgagccc ggtggcggat gccacctgcc gcggcacgtc acccatccgc
    19561 tcccgcagcg cccggccccg gtcggtgagg cccacctcga cccggcgctc atccgccgcc
    19621 gagcgggtac gcaccaccag accggccgcc tccagccgct tgagcagcgg ggagagcgtg
    19681 ccggagtcga gccggagcgc agcgccgagc tcggagaccg tgggggcgtc gtcgtcgtgc
    19741 tcccagagca ccagcagcac caggtactgc gggtaggtca gcccgtgctc gtcgaggatg
    19801 ggccggtaga cgtcggtcag ggcgcgcgac gccgcgtaga gcgcgaagca cacctgccgg
    19861 cgcagtacca gatcatcggt cacgccctga accgtagcgc gcaatcaagt tgtgcacaac
    19921 ttatcggggc gtggagcggt gcggcgccgg tcacccggca ccgctcagcg ctccggcagg
    19981 tacgcctcca gctcgacctc gaccaggaga tccgggtcga tcagcccggc caccaccacc
    20041 atcgtggcga ccgggcgcac cgggccgaac accgcgttgt gcgcccggcc cacctcgtcg
    20101 gcgtagatcc ggtccgtcac gtacatccgg gtccgcacca cgtcccccgg cccggcgccg
    20161 acctcggcca gcgcgtccag gccgatccgg atcgcctgcg cggtctgcgc cgccgcgtcg
    20221 ccggcgtgcg cgacccggcc gtccaccgtg gacgtgcagc cggccgtgat cgccagtgtg
    20281 ccggcccgga ccacccgcga gtagccgtag agcgcctccc acgggccgcc cgagccgagc
    20341 cgggtcacca ccccggcgtc caccggcctc tcggccggct cggccgtcac gcgccggccc
    20401 gcagcgccgc cagcgcctcg gcgactgtga acgcgcccgc gtagagcgcc ttaccggcga
    20461 tcacgccctc cacccccacc ggctccagcg tggccagcgc ccgcagatcg tccagcgtgg
    20521 acacaccacc ggaggcgatc accggggcgt cggtgcggac gcacacctcg cgcagcaggt
    20581 ccaggttcgg cccgcgcatg gtgccgtcct tggtgatgtc ggtgaccacg taccgcgccg
    20641 cgcccgcggc gtccagccgg gccagcacct cgtagaggtc accgccgtcg cgggtccagc
    20701 cgcgcgccga cagggtacgg ccgcgcacgt ccagcccgat cgccacccgg tcgccgtact
    20761 cgccgcagat ccggtcgcac cactgcggat cctccagcgc ggcggtgccg atgttgaccc
    20821 gggccgcccc ggtgccgagc gccgcccgca gcgactcgtc gtcacggatg ccgccggaca
    20881 gctccacctt cacgtccagc ttgccgacca cctcggcgag cagcgcggcg ttggagcccc
    20941 gcccgaacgc c
//
