LOCUS       NZ_CP109812            10846 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Stenotrophomonas sp. SBJS02 chromosome, complete genome.
ACCESSION   NZ_CP109812
VERSION     NZ_CP109812.1
KEYWORDS    RefSeq.
SOURCE      Stenotrophomonas sp. SBJS02
  ORGANISM  Stenotrophomonas sp. SBJS02
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Stenotrophomonas.
REFERENCE   1  (bases 1 to 4836070)
  AUTHORS   Sarkar,J., Bhattacharya,S., Mondal,N., Saran,N. and Ghosh,W.
  TITLE     Whole genome study of Stenotrophomonas sp. SBJS02
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4836070)
  AUTHORS   Sarkar,J., Bhattacharya,S., Mondal,N., Saran,N. and Ghosh,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2022) Microbiology, Bose Institute, Salt Lake, EN
            Block, Sector V, Kolkata 700091, India
REFERENCE   3  (bases 1 to 4836070)
  AUTHORS   Ghosh,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2019) Microbiology, Bose Institute, C. I. T. Road,
            Kolkata 700054, India
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: AUG-2022
            Assembly Method                   :: Unicycler v. 0.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 132.0x
            Sequencing Technology :: IonTorrent; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020428325.2-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 16:31:16
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,430
            CDSs (total)                      :: 4,342
            Genes (coding)                    :: 4,175
            CDSs (with protein)               :: 4,175
            Genes (RNA)                       :: 88
            rRNAs                             :: 5, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 167
            CDSs (without protein)            :: 167
            Pseudo Genes (ambiguous residues) :: 0 of 167
            Pseudo Genes (frameshifted)       :: 136 of 167
            Pseudo Genes (incomplete)         :: 34 of 167
            Pseudo Genes (internal stop)      :: 3 of 167
            Pseudo Genes (multiple problems)  :: 5 of 167
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 00:50:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1204564
            Orig. end                         :: 1215410
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP109812.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10846
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10846
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10846
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5846](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5846)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            460..684
                     /locus_tag="FQS62_RS05665"
                     /old_locus_tag="FQS62_005665"
     CDS             460..684
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479411.1"
                     /locus_tag="FQS62_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005665"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_057499736.1"
                     /transl_table=11
                     /translation="MAIVITLDRMLQERGMTLSELAGRIDITLANLSILKTGKARAIRF
                     STLDAICRELQCTPGELLGHDPTQAQDAD"
     gene            728..2266
                     /locus_tag="FQS62_RS05670"
                     /old_locus_tag="FQS62_005670"
     CDS             728..2266
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1273: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408495.1"
                     /locus_tag="FQS62_RS05670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005670"
                     /product="TerC family protein"
                     /protein_id="WP_154348667.1"
                     /transl_table=11
                     /translation="MEWLADPSIWMGLATLVVLEIVLGIDNLVFIAILADKLPPHQRDR
                     ARVIGLALALLMRLVLLAALAWIMKLTEPLLTLFDHSFSGRDLILLGGGLFLLFKGTME
                     LHERLEGREHHEDGKKVYASFAMVVVQIVVLDAVFSLDSVITAVGMVDNLGVMYAAVTI
                     AMALMLLASKPLTRFVNKHPTVVVLCLGFLLMIGFSLVAEGLGYKIPKGYLYAAIAFSI
                     LVEAFNQWVRFNRERNERRQPFRQRTADAVLRMLGARPANGHDDEAADEHVDAEERLQP
                     AEHEMIRSVLGLADRPVSSVMTVRADVQWIDLARGQEDVVARLVASPHTRLLVGDGDLD
                     SLRGVVQSRDLLADLLQGKPLQLEGNLREPQYVLSSASALQALELIRQHPVPLAVAVDE
                     YGSVEGLVTANDLLAAIAGDLVDTQDERYGVVAQGEDCWEADGALTLDDLQRLAGISLP
                     RSADYMTISGLVLERLGRLPDIGDAVEIAEVRITVLAMEKRRIARLRVERLGHL"
     gene            2401..3536
                     /locus_tag="FQS62_RS22245"
                     /pseudo=""
     CDS             2401..3536
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004147841.1"
                     /locus_tag="FQS62_RS22245"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVAVLSTIGLLMGLYVAWRLFWPLRMPIWMKVVLSLLLVGVAVQL
                     RIVATFWGTMASPEIPKLAIATLAAGSTAVLLLALLMLALDVGLLASRLLRWPRAVAAL
                     RTRSLRPAAALLALLVSGYGVSEGMVVPKPRQIEVSIAGLPAAFDGYRVCS"
     misc_feature    3505..3507
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(3549..4220)
                     /locus_tag="FQS62_RS05685"
                     /old_locus_tag="FQS62_005685"
     CDS             complement(3549..4220)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408497.1"
                     /locus_tag="FQS62_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005685"
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="WP_208043317.1"
                     /transl_table=11
                     /translation="MTVSNTYFLHGWRLFVAIAAVLIAFALGAFALHADVAEGSRAAIR
                     VTARTSFLLFLAAYTASSFASLLPGPFTRFLLRERRIVGLSFAFSHLLHAVAITTFGIL
                     NPAFWPARSVLANLPGTVGYVAILALAITSHRGIARRMGPTAWRRLHVIGMWIIAAVFT
                     YSYFKRVPGNFWYAVPSALLFTAFVVRWIAKRAQALRRSAHARPAQLGTESEPFAGGKG
                     I"
     gene            complement(4223..5008)
                     /locus_tag="FQS62_RS05690"
                     /old_locus_tag="FQS62_005690"
     CDS             complement(4223..5008)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659351.1"
                     /locus_tag="FQS62_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005690"
                     /product="putative DNA-binding domain-containing protein"
                     /protein_id="WP_208043318.1"
                     /transl_table=11
                     /translation="MSESLATLQRRWADHVRDPSMPAPDGVEARRMAVYRRLCIDSLDS
                     LLAGSLPRLKSQLGDACWRDTVEHYYASHACHTPLFPRIAGEFAGWLAVQDTLALPAWA
                     AELAHYESTQQSLHIEARAAGRSLHRVPVDSDVLAVSPLVRVLGYQWPVHEDGALEPVL
                     DTAPVLLMMRRMPEFSLQVDELSPLAYALLSVFSDDGTRVDDVLQTVAEAHGVAPDELR
                     AACIPVLSELCTAGVLVASTHLRECRPAAGTTPSPFFEA"
     gene            complement(5001..5846)
                     /locus_tag="FQS62_RS05695"
                     /old_locus_tag="FQS62_005695"
     CDS             complement(5001..5846)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646321.1"
                     /locus_tag="FQS62_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005695"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_099589052.1"
                     /sec_met_domain="DUF692 (E-value: 2.2e-118, bitscore:
                     392.4, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLPLPFNAAGLGLRRGLIDELLAMPAGAIDFLEVSPDNWIGVGG
                     AHGAALRQLSERHPLTCHGLSLSLGGPDPLDRTLLAQTRAFLDVHQVQLYSEHLSYCAA
                     GGHLYDLLPLPFTAEAVHHVAGRIAQVQDVLGRRIAVENISYYAVAGADLSEIDFINAV
                     LAEADCDLLLDVNNVFVNACNNGYDAFEFLARVPSHRVASLHVAGHFDEDDGFKIDTHG
                     APVKSVVWALLREAYARVGVRPTLLERDFNFPSLAELLGEVAQIRQAQAEACLPEVAHV
                     "
     misc_feature    5878..5887
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.07"
                     /tool="antismash"
     gene            complement(5903..6379)
                     /locus_tag="FQS62_RS05700"
                     /old_locus_tag="FQS62_005700"
     CDS             complement(5903..6379)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005412584.1"
                     /locus_tag="FQS62_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005700"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_099589053.1"
                     /transl_table=11
                     /translation="MSVSTKNTPSSRLPRIGAIGIALAGGLLLAGQAAAIQPLAISAVA
                     MSAAAEGKCGEGKCGANKATTGKPAGKAKVAEGQCGEGKCGDASFARTDRDRDGKVSRA
                     EFNAVAAKRAAEFDRIDTDHDGYISEQEAHDYLRSVYTANGKPMPKGLFSRVAD"
     gene            complement(6475..7119)
                     /locus_tag="FQS62_RS05705"
                     /old_locus_tag="FQS62_005705"
     CDS             complement(6475..7119)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012479418.1"
                     /locus_tag="FQS62_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005705"
                     /product="DoxX family protein"
                     /protein_id="WP_208043411.1"
                     /transl_table=11
                     /translation="MISTASSVYTPRLDAVGRWLSPLALRTLLAWEFFESGREKLGGQN
                     WFADLEGRFPFPFSTLPASLNWQLATWLELVGAVMLLLGLATRSVAYIFWVLTVVAIAA
                     VHWPDQWNGLGELWQGYAITDQGYGNFKLPLLFLAMLLPLILNGGGALSVDRLLAGTPH
                     APAGNDGLGWGVSLIALLLPVAALLPGIGFGGALLGGVLLLGHLLRRRRAA"
     misc_feature    complement(7223..7241)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.64"
                     /tool="antismash"
     gene            7460..8277
                     /locus_tag="FQS62_RS05710"
                     /old_locus_tag="FQS62_005710"
                     /pseudo=""
     CDS             7460..8277
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005408502.1"
                     /locus_tag="FQS62_RS05710"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005710"
                     /product="alpha/beta hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIRTSLLAAALAVAGAAAAAAPPPPAPSSLPGPIRLHRPPSSWCT
                     APSPMAPAGARSSAPCMTGSCRRWPYRIRSPRWPTTSPPPAARLPPRPARWCWSAIAGV
                     ARSSPKRAMTRKYRRWCTWPPSRRMPGNLRRNRAKVSRLVRAWPDCRKGMAT"
     gene            8281..8826
                     /locus_tag="FQS62_RS05715"
                     /old_locus_tag="FQS62_005715"
     CDS             8281..8826
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005415663.1"
                     /locus_tag="FQS62_RS05715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005715"
                     /product="redoxin family protein"
                     /protein_id="WP_208043409.1"
                     /transl_table=11
                     /translation="MAALRGYALPLLLGLLGGAALLLAWPGADAGAQPLDAVPMAGFNG
                     GGPWHNSPPLTLTQLRGQVVLVEFWTYTCSNCLNVAPYVHQWHARYAPQGLRVIGVHTP
                     EFAYEGLPGNVRKAIARLDITWPVVQDNQYRIWNAWGNRFWPALYLLDRQGRVVYRHYG
                     EGDYARTESEIQRLLANP"
     misc_feature    8344..8346
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8885..9625
                     /locus_tag="FQS62_RS05720"
                     /old_locus_tag="FQS62_005720"
     CDS             8885..9625
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019659345.1"
                     /locus_tag="FQS62_RS05720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FQS62_005720"
                     /product="response regulator"
                     /protein_id="WP_208043408.1"
                     /transl_table=11
                     /translation="MNHVPHILVVDDDSEIRQMLADYLQRNGLRVNQADGGRAMRALMD
                     THAVDLVVLDVMMPGEDGLSLCRNLRAGKHRAVPVVLLTARDDETDRIIGLEMGADDYV
                     TKPFSSRELLARINAVIRRTRMLPPNLQVSEAGRQLAFGEWRLDTTARHLLDAQDTAYP
                     LSGAEFRLLRVFLDHANRVLSRDQLLSLTQGRDAELFDRSIDLLVSRVRQRLGDDAREP
                     TYIKTVRSEGYVFSVPVQLLGPDE"
ORIGIN
        1 gctgggcatc ctggccgcac tgctggccgt gccactggtc gcccacgacc gccgctggct
       61 gctcgacagc gtgcacgata ccgctgccgc cgccgcgcat ggcaacgatc tgttcctgca
      121 tttctgcctt ggactgggtg cgatcgtcgc gctgctggtg ctgtgcctgg tgttcctggg
      181 ccatctgctg cggctgctga cgtcggcggc gcgcgagcgg ccgttcaccc acgccaatgc
      241 acagcgcctg caacgcatgg cgtggctgat gctgtcgatg gaggtgctgt cgatcctgat
      301 cggcgcttat gccgcctgga tggggccgga cttcacctgg atggaggtgg gcggcggcat
      361 gtcgattacc ggcctggtcg cggtgctgat gctgttcgtg ctggcacgcg tgttcgccgt
      421 gggtgcggcg atgcgcgatg acctcgatgg tgtcatctga tggcgatcgt catcaccctg
      481 gaccgcatgc tgcaggaacg gggcatgacc ctgtccgagc tggccgggcg catcgacatc
      541 actctggcca acctgtcgat cctgaaaacc ggcaaggcgc gcgccatccg cttttccaca
      601 ctcgatgcga tctgccgtga gctgcagtgc acgcccggtg agctgctcgg gcatgacccg
      661 acccaggcgc aggacgctga ctgagtgctt tcccttttcc cttacctact gacgaaacgg
      721 acctgaaatg gaatggttgg ctgacccctc gatatggatg ggccttgcaa ccctggtcgt
      781 gctggagatc gttctcggca tcgacaacct tgtgttcatc gcgatccttg ccgacaaact
      841 gccgccgcac cagcgtgacc gcgcgcgggt gatcggcctg gcgctggccc tgctgatgcg
      901 gctggtgctg ctggccgcgc tggcctggat catgaaactg accgagccac tgctgacgct
      961 gttcgaccac agcttctccg ggcgtgacct gatcctgctg ggcggtggcc tgttcctgct
     1021 gttcaagggc accatggagc tgcacgaacg gctggaaggc cgcgagcacc acgaggatgg
     1081 caagaaggtc tatgccagct tcgcgatggt cgtggtgcag atcgtggtgc tcgatgcggt
     1141 gttctcgctg gactcggtga tcaccgcggt gggcatggtc gacaacctgg gcgtgatgta
     1201 tgccgcagtg accattgcga tggcgctcat gctgttggcc agcaagccgc tgacccgctt
     1261 cgtcaacaag catcccacgg tggtggtgct gtgcctgggc ttcctgctga tgatcggttt
     1321 cagcctggtg gccgaaggcc tgggctacaa gattccgaag ggctacctgt acgcggcgat
     1381 cgccttctcg atcctggtcg aagcattcaa ccagtgggtg cgcttcaacc gtgagcgcaa
     1441 cgagcgccgc cagccgttcc ggcagcgcac ggccgatgct gtgctgcgca tgctgggtgc
     1501 gcgcccggcc aatggccacg acgacgaagc cgcagacgaa cacgtcgatg ccgaagagcg
     1561 cctgcagccg gcggagcacg agatgatccg cagcgtgctg ggcctggccg atcgcccggt
     1621 gtcgagcgtg atgaccgtgc gtgccgacgt gcagtggatc gacctggcgc gtgggcagga
     1681 ggatgtggtg gcccgcctgg tggcgtcgcc gcatacccgc ctgctggtgg gcgacggtga
     1741 tctggacagc ctgcgtggcg tggtgcagag ccgcgacctg ctggccgatc tgctgcaggg
     1801 caagccgctg cagctggaag gcaacctgcg cgagccgcag tacgtgctgt ccagcgccag
     1861 tgcgctgcag gcgctggagc tgatccgcca gcatccggtg ccgttggcgg tggcggtgga
     1921 cgagtacggc agcgtggaag gcctggtgac cgccaacgac ctgctggcgg ccattgccgg
     1981 tgacctggtc gacacccagg acgagcgcta tggcgtggtc gcccagggtg aagattgctg
     2041 ggaggccgat ggcgcgctga ccctggacga cctgcagcgc ctggcaggta tatcgctgcc
     2101 gcgcagtgcc gactacatga ccatctccgg tctggtgctc gagcgcctgg ggcgcctgcc
     2161 ggacattggt gacgcggtgg agattgcgga agtacgcatc accgtactgg cgatggagaa
     2221 gcggcgcatc gcccgcctgc gggttgaacg cctgggccat ctgtagcgtc gagccctgcg
     2281 cgactggggt tctgtagcgt cgagccatgc tcgactgctt cctgagcagc cgagcacggg
     2341 ctcggctcta cacaacatct tccgcaaccg tcaccatggc gggcccgctt tctttcccgg
     2401 atggttgcag tgctgagtac gatcggtttg ttgatgggcc tctatgtggc ctggcgcctg
     2461 ttctggccac tgcgcatgcc catctggatg aaggtcgtgc tgtcgctgct gctggtgggc
     2521 gttgccgtgc agttgcgcat cgtcgccaca ttctggggca cgatggcctc gccggagata
     2581 ccgaagctgg ccatcgccac gctggccgcc ggctccacgg cggtgttgtt gttggcgttg
     2641 ctgatgctgg cgctggatgt gggtctgctc gcctcccgcc tcctgcgctg gccacgcgcg
     2701 gtagccgcgt tgcgcacgcg gagtctgcgg ccggcggccg ccctgctggc cctgttggtc
     2761 agtggctacg gcgtcagcga gggaatggtg gtacccaaac cccggcagat cgaggtgagc
     2821 attgccggct tgcctgccgc gttcgatggc tatcgcgtct gcagttgacc gacatccacg
     2881 ccagccgcct gctgaccggc gactgggtgc gcagggtagt ggatgagagc aacgcactga
     2941 cgccggacct gatcgtgatc accggcgacc tgatcgacgg cagtgtcgag gcccgccgtg
     3001 acgacgcgcg cccactcgcg gacctgcggg cgccggacgg tgtcgtcgcc atcaccggca
     3061 accacgagta ctacgcgcag tatcgggcgt ggatgcaggc gttccgcgcg ctgcacatgc
     3121 aggtgctgga gaacagtcat ctgcaggtgc ggcgcggcga tgcggcgctg accatcgccg
     3181 gtgtcaccga tccggtggcc gcgcgctacg gcctgccgct gccggatctg gaggccgcgt
     3241 tggccggtgc cgatccgtcc gcgccggtga tcctgcttga tcatcgcccg cgcaatgcgc
     3301 gcgaggcggc ggcgcgtggg gtgaagctgc agctgtccgg gcatacccac ggcgggcaga
     3361 tcatcggcat ggaccagttg gtgaagcggg ccaacggtgg ctatgtctcc gggcgttatg
     3421 aagtggacgg catgaccctg tacgtgagca acggtgcagg gctgtgggcc ggtttcccgg
     3481 cgcgcatcgg cgttccatcg gagattaccc tggtgacgtt gcgcggcgcg ccgtgatctc
     3541 tactggggtc agatcccttt gccaccggcg aagggctctg actctgtgcc caactgcgcg
     3601 gggcgcgcat gcgcacttcg gcgcagcgcc tgcgcccgct tggcgatcca gcgcaccacg
     3661 aaggcggtga acagcagcgc cgacggcacc gcataccaga agttgcccgg cacgcgcttg
     3721 aagtacgagt aagtaaacac cgccgcgatg atccacatgc cgatcacgtg caggcgacgc
     3781 cacgcggtgg ggcccatgcg gcgggcgatg ccacggtgcg aagtgatggc caaggcgagg
     3841 atggcgacgt agcccactgt gcccggcagg ttggccagga ccgagcgcgc tggccagaac
     3901 gcagggttga ggatgccgaa ggtggtgatc gccactgcat gcagcaggtg cgagaacgcg
     3961 aacgacagcc cgacaatgcg acgctcgcgc aacaggaaac gggtgaacgg gcccggcaga
     4021 aggctggcga acgacgatgc cgtgtatgcc gccaggaaca gtaggaacga tgtgcgtgca
     4081 gtgacccgga tcgcagctcg gctgccctcg gccacatcgg catgcagggc gaacgcgccc
     4141 agcgcgaagg cgatcagtac cgccgcgatg gccacgaaca ggcgccagcc gtgcaggaag
     4201 tacgtgttgg aaacagtcat ggtcaggcct cgaagaatgg agaaggggta gtgccggccg
     4261 ctggccggca ttcccggaga tgagtcgacg caaccagaac gccggccgtg cagagttcgc
     4321 tcagcactgg aatgcaggcc gcacgcagct catccggcgc aacaccatgt gcttcagcca
     4381 cggtctgcaa tacgtcatcc acacgcgtgc cgtcatcgct gaagaccgac agcagcgcgt
     4441 aggccagcgg tgacagttcg tcgacctgca ggctgaattc aggcatgcgg cgcatcatca
     4501 gcagcacagg agctgtatcc agcaccggct ccagcgcccc gtcctcatgt accggccact
     4561 ggtagcccag cacccgcacc aacggcgaaa ccgccagcac atcactgtcc accggaacgc
     4621 ggtgtagcga acgcccggcg gcgcgcgctt caatgtgcag cgactgctgc gtgctctcgt
     4681 agtgcgcaag ttccgctgcc caggccggca gcgccagcgt gtcctgcacc gccagccagc
     4741 ccgcgaactc gccggcgatc cgtgggaaca gcggggtgtg acaggcgtgg ctggcgtagt
     4801 agtgctccac tgtgtcgcgc cagcaggcat cgcccagctg cgacttcaac cgcggcaggc
     4861 tgcccgccag caggctgtcc agactgtcga tgcacaggcg gcggtagacc gccatccgcc
     4921 gtgcctcgac gccatcgggc gcaggcatcg acgggtcccg cacatgatcg gcccagcgcc
     4981 gttgcagcgt agccagcgac tcagacatgg gccacctcgg gcaaacatgc ctcggcctgc
     5041 gcttggcgga tctgcgcaac ctcgcccagc agttctgcaa gcgacgggaa gttgaagtcg
     5101 cgttcgagca gcgtggggcg tacgcccacc cgcgcatagg cctcgcgcaa tagcgcccag
     5161 accacacttt tcaccggcgc gccgtgggtg tcgatcttga agccatcgtc ttcatcgaag
     5221 tggcccgcca cgtgcagcga ggcgacacgg tgggacggca cgcgggccag gaattcgaag
     5281 gcgtcgtaac cgttgttgca ggcgttgacg aagacgttgt tgacgtccag cagcaggtcg
     5341 cagtcggctt cggcgagcac ggcgttgatg aagtcgatct cgctcaagtc cgcgccggca
     5401 acggcgtagt aggagatgtt ctccaccgcg atgcgccggc ccagcacgtc ctgtacctgg
     5461 gcgatgcggc cggccacatg gtgtacggcc tcggcggtga acggcagtgg cagcagatcg
     5521 tagagatggc caccggcggc gcagtagctc aggtgttcgc tgtacagctg cacctggtgc
     5581 acgtcgagga aggcacgggt ctgtgccagc agggtgcggt ccagtggatc aggaccgccc
     5641 agcgacagtg acagtccgtg gcaggtcaag gggtggcgct cgctgagttg gcgcagcgcg
     5701 gcgccgtgtg caccgccgac gccgatccag ttgtcggggg agacttcgag gaagtcgatg
     5761 gcaccggccg gcattgccag cagttcgtcg atcaggccac ggcgcaggcc aagaccggcg
     5821 gcattgaaag gcaggggcag ggacatggcg gatgctccag agggagggcg ccgcctcgaa
     5881 ggcggcgccg ggtgaacgtc gatcaatcgg cgactcggga gaacaggccc tttggcatcg
     5941 gcttgccgtt ggcggtgtaa acgctgcgca ggtagtcgtg cgcttcctgc tcgctgatgt
     6001 agccgtcgtg atcggtgtcg atgcggtcga actcggcggc acgcttggcg gccacagcgt
     6061 tgaactcggc gcgcgagacc ttgccgtcgc ggtcacggtc ggtgcgggca aacgaggcgt
     6121 cgccgcactt gccttcgcca cactggccct cggccacctt ggccttgcca gcgggcttgc
     6181 cggtggtggc cttgttggcc ccgcacttgc cttcaccgca cttgccttcg gcggcggcgc
     6241 tcatggccac cgcgctgatc gccagcggtt ggatcgcggc ggcctggccg gccagcagca
     6301 ggccaccggc cagggcgatg ccgatggcac cgatgcgcgg caggcgggag gagggggtgt
     6361 tcttggtcga gacggacatg gtggtgactc cttgggaaag cacgcggggc gtgcgggatg
     6421 gacgccgccg aagaggcgac ggaaagcgaa acgcgcgggt acaggggaat cagctcaggc
     6481 ggcgcggcgg cgacgcagca gatggcccag cagcagcaca ccgccgagca gggcaccgcc
     6541 gaagccgatg ccgggcagca gcgcggcaac cggcagcagc agggcgatca ggctgacgcc
     6601 ccagcccagg ccgtcattgc cggcgggggc atgcggcgtg ccggccagca gccggtccac
     6661 gctgagcgcg ccaccgccgt tgaggatcaa tggcagcagc atggccagga acagcagcgg
     6721 cagtttgaag ttgccgtagc cctggtcggt gatcgcatag ccctgccaga gttcacccag
     6781 gccgttccat tggtcgggcc agtgcacggc ggcgatggcg accacggtca acacccagaa
     6841 gatgtaggcc accgagcgcg tcgccaggcc aagcagcagc atcaccgcgc ccaccagttc
     6901 cagccaggtg gccagctgcc agttcagcga cgcgggcagg gtggagaacg ggaacggaaa
     6961 gcggccttcc agatcggcga accagttctg accgcccagc ttctcgcggc cggattcaaa
     7021 gaactcccag gccagcaggg tgcgcagcgc caggggtgac agccagcggc cgacggcatc
     7081 caggcggggg gtatacacgg aagaggcggt gctgatcatg gtggtgtcct gcgggccagt
     7141 ggtcgatgaa ggccattcca ggcggcgcag gtatcggcaa cgtgtgccgt tgcctggggt
     7201 tttgtcagcg actgtggtcg cggccggggt ttcgtacagt cagatacaaa gacgatgcgt
     7261 tgatgcacat cgggcgttgc gcgcccgcat gcggggagcg atatccaccc ggcagcgccc
     7321 agccaggacc ggcgcccgaa tgtatcccac tgtagaaacc gcccgcgctc tacagtccgg
     7381 tacaactccg cgctacggag aaacagcggc gatacaccgg caggcggaaa tggctactcc
     7441 caacaccgga gtgtcaccca tgatccgtac ctcgctgctt gccgccgcgc tcgccgttgc
     7501 cggcgccgcc gccgccgccg ccccgccccc ccccgccccg tcttcgctgc ccgggccgat
     7561 acggctgcac cgcccaccgt catcctggtg cacggcgcct tcgccgatgg ctccagctgg
     7621 agcaaggtca tcagcaccct gcatgactgg aagctgccgg cggtggccgt acagaatccg
     7681 ctcacctcgt tggccgacga cgtcgccgcc acccgccgcg cgattgccgc cgcgcccggc
     7741 aaggtggtgc tggtcggcca tagctggggt ggcacggtca tcaccgaagc gggcaatgac
     7801 ccgaaagtac aggcgctggt gtacgtggcc gccttcgcgc cggatgccgg gcaatcttcg
     7861 gcgcaacagg gcgaaggttt cccggttggt ccgggcctgg cccgactgca ggaaagggat
     7921 ggctacctga ccttgccggc ggatgccatc gcccaggact tcgcgccgga cgtgatgaaa
     7981 aagtcggccg cactgctgta cagcacgcag gtcccgttga aggccagcgc gctcggcgag
     8041 gtggtgaacg ttgcggcgtg gcgcagcaag ccgagctggt acgtactcag ccgcgatgac
     8101 cgcatgctgt cgccgcagct gcaggccgcg accgcacgtc gcattggtgc acaactgcaa
     8161 tcggtcggca gcagccatgt gtcgctgctt tcgcatccag cgcaggtggc cgacagcatc
     8221 ctggaagcag cgggggtgaa gccggcggaa ctgccgctgg ccgagcaggg tggctgagcg
     8281 atggccgcac tgcgagggta cgcattgccg ctgttgctgg gcctgctggg cggagcggcg
     8341 ttgttactgg catggcccgg tgcggatgcc ggcgcgcagc cgctcgatgc agtaccgatg
     8401 gcggggttca acggtggcgg gccctggcac aacagcccac cgctcacgct gacgcagttg
     8461 cgggggcagg tggtgctggt tgagttctgg acctacacct gcagcaactg cctcaacgtg
     8521 gcgccgtatg tccaccagtg gcatgcacgg tacgcgccgc agggcctgag ggtgatcggc
     8581 gtgcatacgc cggagttcgc ctatgaaggg ctgcctggca acgtgcgcaa ggccatcgca
     8641 cggttggata tcacctggcc ggtggtgcag gacaaccagt accggatctg gaacgcctgg
     8701 ggcaaccgct tctggcccgc gctgtacctg ctcgaccggc aggggcgtgt ggtctaccgc
     8761 cattacggcg agggcgacta cgcacgtacc gaaagcgaga tccagcgcct gctggccaac
     8821 ccctgagccg cgctaccatg gccgcgccgc gcggcgctgt ccccctgcct tcatcgagaa
     8881 cgcaatgaac cacgtaccgc atatcctggt cgtcgacgat gacagcgaga tccgccagat
     8941 gctggctgac tacctgcaac gcaacggcct gcgcgtgaac caggccgacg gtggccgggc
     9001 gatgcgcgcg ctgatggata cccatgccgt ggatctggtg gtgctggacg tgatgatgcc
     9061 gggcgaggat ggactgagcc tgtgccgcaa cctgcgcgcc ggcaagcatc gtgcggtgcc
     9121 ggtggtgctg ctgactgccc gcgacgacga gaccgatcgc atcatcggcc tggaaatggg
     9181 tgctgacgac tacgtgacca aacccttctc ttcgcgcgaa ctgctggcac gcatcaatgc
     9241 agtgatccgc cgcacccgga tgctgccgcc gaacctgcag gtgagcgaag caggtcgcca
     9301 gctggccttc ggcgagtggc gcctggacac cactgcacgc catctgctgg atgcgcagga
     9361 caccgcgtat ccgctcagtg gcgccgagtt ccgcctgttg cgcgtgttcc ttgatcacgc
     9421 caatcgggtg ctcagccgcg accagctgct cagcctcacc cagggccgcg atgccgaact
     9481 gttcgatcgc tcgatcgacc tgctggtcag ccgcgtgcgg cagcgcctgg gtgacgacgc
     9541 acgcgagccg acctacatca agaccgtgcg cagcgaaggc tatgtgttca gcgtgccggt
     9601 gcagttgctg gggccggacg aatgaacatc ggcgcacgcc gtccacgctg gccgcgcacg
     9661 ctgtcggcgc ggctgctgct ggtgctgctg ggcggactgg ccctggccca cgcactgtcc
     9721 ttcggcctgc tgttcttcga acgttaccag tccacccgca gcatgatgct gcgcaacctc
     9781 gatgaggatg tggcggtcag tgtcgcgctg ctggagcacc tgcctgcggc gcaacgcgat
     9841 gcctgggtgc ctcggctgga gcggcgcacc taccgttacc tgctgcgccc ggccgcggcc
     9901 ggaccagggc tgcagaccga tcgtgcacgc caggtcacgg cgatcatcga cgacagcctg
     9961 cagcaccgct atccgttgca ggcgcgtcag gtggctcgcc tgccggagcg gttcgaggtg
    10021 gaactgcgcc tgcacgacgg tacccccgtg accattgaag tcacctcgtc gggcctgccg
    10081 ctggcgcgtt ggctgcccgc cgtgctgctg ctgcagctgg cgctgctgct ggtctgcgcg
    10141 tggctggcgg tgcgcctggc catgcgcccg ctgcagcagc tgtcgcatgc ggtggagcat
    10201 ctgcagccgg gcaaggacgg gcccgcactg cctgaagatg gtcctgcgga agtaggcggt
    10261 gcggcggccg cactcaatgc actgcaggca cgcattcgtg gccatgtcag tgagcgcctg
    10321 cagatcctgg ccgcgatctc gcatgacctg cagactccca tcacgcgcat gaagcttcgg
    10381 gtggagaccc tgcctgaaga cagcacccag cagcggctgc tggccgacct cgatcacctg
    10441 ggtcaactgg tgcgtgaggg cgtgtcctat gcgcgcagca gccacgtcgc cagtggcgcg
    10501 ccggtggcga tggacctggg cgcattcctg gccagtgtgg tcggcgatta cgaggatatg
    10561 ggcaagccgg tcagtggtgg tgcgccggct ggactggtcg tgcagacctg gccgcagccg
    10621 ctgcgccggg tggtcggcaa tctggtcgac aacgcgttgc gttacgccgg tgccgccgag
    10681 atcgaggcgg gtcgcgatgg ggccggaagg gtgtggatca gcatttccga ccgtggcccg
    10741 ggcattcccg aggaccagct gcaggcagtg ctggcgccgt tccaccgact ggaaagctcg
    10801 cgcaatcgcg gtaccggcgg gactggcctg ggcctggcca tcgcgg
//
