LOCUS       NZ_CP084541            24335 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces marincola strain SCSIO 64649 chromosome, complete
            genome.
ACCESSION   NZ_CP084541
VERSION     NZ_CP084541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Strepomyces indimicinicus sp. nov., an antibiotic producing
            actinomycetes isolated from the marine environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Sciences, 164 Xingang West Road, guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. V6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 444.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020410765.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,763
            CDSs (total)                      :: 5,689
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 74
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 21 of 77
            Pseudo Genes (incomplete)         :: 60 of 77
            Pseudo Genes (internal stop)      :: 2 of 77
            Pseudo Genes (multiple problems)  :: 6 of 77
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:57:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6125650
            Orig. end                         :: 6149985
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24335
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="30"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24335
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24335
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14335](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14335
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(480..1412)
                     /locus_tag="LC193_RS27080"
                     /old_locus_tag="LC193_27080"
     CDS             complement(480..1412)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133326.1"
                     /locus_tag="LC193_RS27080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27080"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_226077999.1"
                     /transl_table=11
                     /translation="MGAGHHHGGPPRGGTAGAAHRGRLTAALAIACVLLVAELVGAALT
                     GSLALLADAGHVATDAVGIGMALVAIHVANRPVRSDRRTFGFARVEILAALANCVLLLG
                     VGGYILIEAIGRLREPAEVPGGLTVVFGVAGLLLNCVSLALLMRGQRESLNVRGAFLEV
                     AADALGSVAVIAAALVIMFTGWQAADPVASLLIALLIVPRAVRLAREAIDVLLETAPKD
                     VRIAEVRDHVLGLPGVEGLHDLHVWTITSGMPALSAHVVVARETLDAVGHEEMLHALQG
                     CLGEHFDVAHCTFQLEPSGHAAHEPGLCH"
     misc_feature    1483..1497
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1576..2550)
                     /gene="galE"
                     /locus_tag="LC193_RS27085"
                     /old_locus_tag="LC193_27085"
     CDS             complement(1576..2550)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-205). E-value:
                     4.1e-11. Score: 34.4. Matches aSDomain:
                     nrpspksdomains_LC193_RS27085_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003958864.1"
                     /locus_tag="LC193_RS27085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27085"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_226078000.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.9e-17, bitscore:
                     60.1, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.2e-13,
                     bitscore: 47.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSWLITGGAGYIGAHVVETMRAAGERVVVLDDLSSGRAGRLPADV
                     PLVRGSILDRGLLDTTLAEHGVRGVVHLAAKKQVAESVAEPLAYYRSNVHGLTVLLDAV
                     VAAGVREFVFSSSAAVYGTPETGTVTEDTPCRPLSPYGETKLAGEWLVRAAGRAHGIAT
                     ACLRYFNVAGATRPELADAGAANVVPMFFERIAAGRPPEIFGADYPTPDGTCVRDYVHV
                     ADLADAHLLAARHLADAAPGADLTVNVGTGRGASVRELAALVADVTGFAGPPRVAGRRP
                     GDPARVVASVELARERLGFTARRGLPDMVSSAWEGWRRTHGGL"
     aSDomain        complement(1936..2355)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC193_RS27085_NAD_binding_4.1"
                     /evalue="4.10E-11"
                     /label="LC193_RS27085_NAD_binding_4.1"
                     /locus_tag="LC193_RS27085"
                     /protein_end="205"
                     /protein_start="65"
                     /score="34.4"
                     /tool="antismash"
                     /translation="GVRGVVHLAAKKQVAESVAEPLAYYRSNVHGLTVLLDAVVAAGVR
                     EFVFSSSAAVYGTPETGTVTEDTPCRPLSPYGETKLAGEWLVRAAGRAHGIATACLRYF
                     NVAGATRPELADAGAANVVPMFFERIAAGRPPEIFG"
     CDS_motif       complement(1987..2106)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LC193_RS27085_0002"
                     /evalue="2.00E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="LC193_RS27085"
                     /protein_end="188"
                     /protein_start="148"
                     /score="1.2"
                     /tool="antismash"
                     /translation="EWLVRAAGRAHGIATACLRYFNVAGATRPELADAGAANVV"
     CDS_motif       complement(2461..2547)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_LC193_RS27085_0001"
                     /evalue="2.00E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="LC193_RS27085"
                     /protein_end="30"
                     /protein_start="1"
                     /score="14.0"
                     /tool="antismash"
                     /translation="SWLITGGAGYIGAHVVETMRAAGERVVVL"
     misc_feature    2730..2746
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.32"
                     /tool="antismash"
     gene            2796..4634
                     /locus_tag="LC193_RS27090"
                     /old_locus_tag="LC193_27090"
     CDS             2796..4634
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676195.1"
                     /locus_tag="LC193_RS27090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27090"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_226078898.1"
                     /transl_table=11
                     /translation="MSTAILTGPPPPGSPLESDLRELGFSVLVLDTAAGLAAELAAVPP
                     GRRVAVVDPRFVGHLHSLRLGLTDPRFPVAALPGAVTALPEGRAALAAAVAEAAPAPGP
                     PTGTHGRAVAAPPAGTCLPEELAARLTAAGSPPHRPELGTLVAAVPETAEQRAGAEADV
                     AAVDEEAVRLRSAVKARDGFFTTHFVSPYSRHLARWCARRGLTPNQVTTASLVTALIAA
                     GCAATGTRGGFVAAGLLLLLSFVLDCADGQLARYALRYSTLGAWLDATFDRAKEYAYYA
                     GLALGAARGGDDVWALALGAMVLQTCRHIVDFAFNEAHPPAPGGAAGATALSGRLDRIG
                     WTVWLRRMIVLPIGERWALIALLTAFTTPRATFVVLLVAAGFAACYTTAGRLLRSRRLP
                     GGGPGTAAALGGLADNGPLAEAAARVRPRPAGSAFTAPLWAAAGTALLVGLLLVPGVAG
                     GWAAVAAALAYAVCAGRATAAPLVRPFDWVLPPLFRGGEYLAILVLAAESGVNGALPAA
                     FCLVAACAYHHYDTVYRLRGGAGAPPRRLVLVTGGHEGRVLVVSAAAALWAGGQGFTVA
                     LAVLGGATAFLVLGESIRFWISAQAPAVHDETGEPA"
     gene            4631..5401
                     /locus_tag="LC193_RS27095"
                     /old_locus_tag="LC193_27095"
     CDS             4631..5401
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640650.1"
                     /locus_tag="LC193_RS27095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27095"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_226078001.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 7e-11, bitscore:
                     41.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVIDAEGENGRTVLDLTLA
                     NFAEVGLTEAAIVVGYRKEAVYERKDALERSYGVRLTLIDNDRAEEWNNAYSLWCAREV
                     IEEGVILANGDTVHPPSVERTLLAAQAAGGPGAGTGRVILALDTVKKLADEEMKVVADP
                     EKGVRRITKLMDPAEATGEYIGVTLIEPGAAAPLADALRTTFERDPQLYYEDGYQELVH
                     RGFRIDTAAIGDVSWVEIDNHDDLARGREIACRY"
     gene            5389..6450
                     /locus_tag="LC193_RS27100"
                     /old_locus_tag="LC193_27100"
     CDS             5389..6450
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308910.1"
                     /locus_tag="LC193_RS27100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27100"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_226078002.1"
                     /sec_met_domain="Fe-ADH (E-value: 4.3e-20, bitscore: 70.2,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVSVDIMAGALDNLAGLLADQRISSSGRLAVAISN
                     GSGAALRDRLAPALPGADWYEVAGGTIDAAVQLADAMRPGHYDAVVGLGGGKIIDAAKY
                     AAARVGLPMVAVATNLSHDGICSPVSTLDNDAGRGSYGVPTPIALVIDLDVIRRAPVRY
                     VRSGIGDAVSNISAIADWELSHRETGEQIDGLAAAMARQAGEAVLRHPGDCGDDAFLTV
                     LSEALVLSGIAMSIAGHTRPSSGACHEISHALDVLHPRRSAPHGEQVGLGAAFAMHLRG
                     AVDQCGLIADTLRRHGLPVLPGHIGFSTDEFVAAVAFAPQTRPGRYTILEHLDLSTDQI
                     RDAYADYVKTIGS"
     gene            6428..7213
                     /locus_tag="LC193_RS27105"
                     /old_locus_tag="LC193_27105"
     CDS             6428..7213
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962488.1"
                     /locus_tag="LC193_RS27105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27105"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_226078003.1"
                     /transl_table=11
                     /translation="MSKPSVAELRPVVHPPGVKDRRSGEHWAGRLYMREISLRWTRHLV
                     NTRISPNQLTYLMVVAGVAAGAALLVPGLAGAVAAALLIQLYLLLDCVDGEVARWRGQT
                     SITGVYLDRVGHYLAEAALLVGFGVRAADVFAAEEAAPNWLWAFLGTLAALGAILIKAE
                     TDLVDVARTRGGLPAARDDAAIPRSSGLALARRAAAALKFHRLVGGVEASLLILLVAVL
                     DLARGDLFFTRLGVALLAAVALVQTLLHLVSVLASSRLR"
     gene            7261..8106
                     /locus_tag="LC193_RS27110"
                     /old_locus_tag="LC193_27110"
     CDS             7261..8106
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018888991.1"
                     /locus_tag="LC193_RS27110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27110"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_226078899.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-08,
                     bitscore: 33.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDRPEALRALLDSVAAQDGAAIDVVVVGNGARLPGLPPGVRSLE
                     LPQNLGIPGGRNVGIEAFGPGGSEVDVLLFLDDDGRLPDKNVAETVRAAFEADPQLGIV
                     SFRITDPESGTTQRRHVPRLRASDPLRSSRVTTFLGGANAVRTHVFQQVGGLPDNFFYA
                     HEETDLAWRALDAGWHIDYRADLVLHHPATAPSRHAVYHRMIARNRVWLARRNLPLPLV
                     PVYLMNWLLLTLLRRPSRPALAAWFGGFVEGWRTPCGPRRPMRWRTVWRLTRLGRPPVI
                     "
     gene            8187..9101
                     /locus_tag="LC193_RS27115"
                     /old_locus_tag="LC193_27115"
     CDS             8187..9101
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972239.1"
                     /locus_tag="LC193_RS27115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27115"
                     /product="ABC transporter permease"
                     /protein_id="WP_226078004.1"
                     /transl_table=11
                     /translation="MSETTHDSAPPRDVPLAELAARHGLSVSGARPSLPGYVRQLWGRR
                     QFIVAFSQAKLSAQYSQAKLGQIWQVLTPLLNALVYYLIFGLLLDGRGDMENDEYVPFL
                     VTGVFVFTFTQNSVMSGVKSISGNLGLVRALHFPRASLPISLSLQQLQQLLFSMVILFA
                     IVVAFGHFPEFNWLLVIPALLLQLVFNTGLALFFARLGSATPDLAQLMPFVLRTWMYAS
                     GVMFPLAYMVEKRAEWPLWVADVLAANPAAVYMDLVRYALIDGTYRDSIEPVTWLFGLG
                     WALVVGIGGFVYFWKAEERYGRG"
     gene            9094..9888
                     /locus_tag="LC193_RS27120"
                     /old_locus_tag="LC193_27120"
     CDS             9094..9888
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432678.1"
                     /locus_tag="LC193_RS27120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27120"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_086157215.1"
                     /transl_table=11
                     /translation="MAEQDISTGGPGGQRVPTVIADGLHIVYRVHGGGGRGTATAALRR
                     MVRRERGFKMREVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPPERGKVYT
                     DGQPSLLGVNAALMNDLTGERNVILGGLAMGMSRDEIKGRYQEIVDFSGINEKGDFISL
                     PMRTYSSGMQARLRFSIAVAKEHDVLMIDEALATGDKKFQRRSEAKVREMRAEAGTVFL
                     VSHNNKSIRDTCDRVLWLEKGELVMDGPTDQVLKAYEEETGK"
     misc_feature    complement(9938..9952)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.0"
                     /tool="antismash"
     misc_feature    complement(9944..9959)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.92"
                     /tool="antismash"
     gene            10001..10918
                     /gene="hpnC"
                     /locus_tag="LC193_RS27125"
                     /old_locus_tag="LC193_27125"
     CDS             10001..10918
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019527751.1"
                     /locus_tag="LC193_RS27125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27125"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_404819564.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-41,
                     bitscore: 140.8, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 3.3e-37, bitscore:
                     126.6, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEHSDAGPDGGRAVLAKAAHENFPVAPRFLPAAWREDLMALYG
                     FARLVDDIGDGDLAPGGADAAHLGVDPAGAADRLLLLDAVEADLRRVFASATGGTPPRH
                     PLLRELIPTVRRSGLAPGPFLDLIEANRVDQRVRRYATYADLLGYCELSANPVGRLVLA
                     VTGTATPERIRRSDAVCTALQLIEHLQDVAEDLARDRIYLPADVMDRFFVTEADLAAPT
                     ANASVRTLVAYLTDRARRLLEEGAPLMSGVSGRLRLLLAGFIGGGHAAARAIEDAGYDV
                     LAGPPRASKGGLLYAAATTLRRGT"
     gene            10930..11859
                     /gene="hpnD"
                     /locus_tag="LC193_RS27130"
                     /old_locus_tag="LC193_27130"
     CDS             10930..11859
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552437.1"
                     /locus_tag="LC193_RS27130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27130"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_226078006.1"
                     /sec_met_domain="phytoene_synt (E-value: 5.9e-61, bitscore:
                     204.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.2e-67,
                     bitscore: 224.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTRSPLPPAVVAAYRYCESIAEQHARNFSYGARLVPAPKRRALT
                     AVYAFARRVDDIGDGDLAPEAKEERLAAGRAMLARVRDGAVPEDDTDPVAVALAHAGRR
                     FPIPLDALDELIDGVLMDVRGHTYETWEDLRLYCTRVAGTIGRLSLGVFGVRPGAPGTE
                     RAEEYADTLGLALQLTNILRDVREDAERGRVYLPAEDLRKFGCPEGPDVVAPGRDADFT
                     GLIRFEVRRARELFVRGSRLLPLLDRRSGACVTTMAGIYHRLLDRIEAEPRAVLRGRVT
                     LPAGHKALVAARGLTGLDARRAARREPL"
     gene            11856..13280
                     /gene="hpnE"
                     /locus_tag="LC193_RS27135"
                     /old_locus_tag="LC193_27135"
     CDS             11856..13280
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542866.1"
                     /locus_tag="LC193_RS27135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27135"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_226078007.1"
                     /transl_table=11
                     /translation="MTSTRRPGHTIVIGGGLAGTTAALALADAGRAVTLVESRPRLGGL
                     AFSFRRDSPAGPLTVDNGQHVYLRCCTAYRGFLQRVGAAALAPLQPRLDVPVLDAATGR
                     LGRIRRTGLPVPLHLAGSLARYPHLSPGERAAAARATLALRALDPDDPRLDRQDFAAWL
                     RRHGQTDRAVAALWDLIGVATLNARAGDVSLGLAAMVFRTGLLTAPGAADLGIPRAPLG
                     ELHDTRARAALDRAGVTTLLSTRARRLAPARGGGWHVTVAAPRGLPRAAHELTADSVVL
                     AAPHDVAARLLPAGAMTDPGGLRHIGTAPILNVHVVYDRQVLRRPFLAALGSPVQWIFD
                     RGGPAGLGAPGPGRPQYLALSQSAAGEEIQLPTDVLRKRYLPELARLLPRAARARVTDF
                     FVTRERAATFAPAPGVGRLRPGPRTRAAGLYLAGAWTATGWPATMEGAVRSGHAAARAV
                     LAGGPAPEHTTAEESA"
     gene            13277..14335
                     /locus_tag="LC193_RS27140"
                     /old_locus_tag="LC193_27140"
     CDS             13277..14335
                     /EC_number="2.5.1.-"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944202.1"
                     /locus_tag="LC193_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27140"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_226078008.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1e-54, bitscore:
                     184.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQPAHTDGAVPALLERGRALAAPALREAVGRLAPPMNTVAAYHF
                     GWIDADGRPAASDSGKAIRPALALLSAEAAGAAPETGVPGAVAVELVHNFSLLHDDLMD
                     GDEQRRHRDTVWKVHGPAQAILVGDALFALANEVILAPGTAGAARAARRLAAASRRLVD
                     GQAQDIAFEHREHVTVAECLEMEGNKTGALLACAASIGAILGGADDALAESLELYGQHL
                     GLAFQAVDDLLGIWGDPRSTGKRTWSDLRQRKKSLPVVAAQAARGPAAERLTALLTADA
                     KKTQEEFDDFDEAEFATRAALIEEAGGRVWTEGEARRQYDAAVAALHRVDVPAPVRERL
                     TALADFVVVRQK"
     misc_feature    complement(14359..14373)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            14626..15324
                     /locus_tag="LC193_RS27145"
                     /old_locus_tag="LC193_27145"
     CDS             14626..15324
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262554.1"
                     /locus_tag="LC193_RS27145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27145"
                     /product="alpha-ketoglutarate-dependent dioxygenase AlkB"
                     /protein_id="WP_226078009.1"
                     /transl_table=11
                     /translation="MDEDTLFPRERVEIAPGAVHLPGWLGRERSADLLAACRAWALPPA
                     GLRTVLMPNGGRMSVEQVSLGWHWYPYGYARTVVDGDGAPVKPFPAWLGAWAARAVADA
                     GPGVDAAAYAPAALPFDIALVNFYGPDARMGMHRDSDERVSAPVVSFSLGDTCVFRFGT
                     PEGRGRPWQDIELRSGDAFVFGGPSRLAYHGVPRTRPGSAPAGLGLSGRLNVTVRVSGF
                     GAPEDGVPQA"
     gene            15465..16853
                     /locus_tag="LC193_RS27150"
                     /old_locus_tag="LC193_27150"
     CDS             15465..16853
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="LC193_RS27150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27150"
                     /product="ATP-binding protein"
                     /protein_id="WP_318842193.1"
                     /transl_table=11
                     /translation="MPEQPRHGAGAPRHSRLAFGEPGGGEPGTRRRLLRLAVLPAVLVA
                     VIATAALVYVLARGGPGTGRGSCPVWTVLATALVLVCAVVAGAAIRAAGEARAHGARLT
                     GLRRQAARGRVELQALLVKVERGERIKPPEGPAPAEPAEDQLDQLRHEIEAAQHAAESA
                     VFQASSLVRGGEDERVEVFVSLARRLQSFVHRQIEYLEELEEEVEDPELLKGLFHVDHL
                     ATRVRRHAENLAVLGGAVPRRQWSRPVGMSEVLRSCVAEVEHYSRVKLVPPIEGSVRGH
                     AVADVIHLLAELVENATEFSAPQTQVLLRVQRVAAGIAIEVEDRGLGMTPAEQVRMNAV
                     LAGAERADVTDLLEDGRVGLFVVATLARRHDIVVQLQSNVYGGVQAVLMLPSDLLGDDS
                     DAGHVRGRAIRAIEAAPRDGLPRAPLTRRPSLVPGPGGDEEDPAPGLIAASPGPAGRPE
                     DAEA"
     gene            complement(16936..18672)
                     /gene="metG"
                     /locus_tag="LC193_RS27155"
                     /old_locus_tag="LC193_27155"
     CDS             complement(16936..18672)
                     /EC_number="6.1.1.10"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004825 - methionine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354743.1"
                     /locus_tag="LC193_RS27155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27155"
                     /product="methionine--tRNA ligase"
                     /protein_id="WP_226078010.1"
                     /transl_table=11
                     /translation="MARHLITSALPYINGIKHLGNMVGSMLPADVYARYLRGRGHDVLY
                     ICATDEHGTPAELAAKAAGLPVAEFCARQHEAQKAVYDGFGLRFDHFGRTSSAQNIEIT
                     QHFARRLHENGFIEERSTRQVYSLADGRFLPDRYIVGTCPYCGYEAARGDQCENCTRVL
                     DPTDLLEARSAVSGSTELEVRETTHLFLLQSKLEREVEAFVDAAGEEWPTLSSSIARKW
                     LTEGLHDRAITRDLEWGVPVPADVWPELAAEGKVFYVWFDAPIGYIGATKEWADAAGAG
                     EERDWRAWWYDADASVRYTEFMAKDNVPFHTVMFPATQLGTREPWKKVDVVKSFNWLTY
                     YGGKFSTSQNRGIFADAALDVLPADYWRYFLIAGAPESDDASFSWELFASVVNKDLADT
                     LGNFVNRVLTFSRKRFGDQVPAGHAAGEAEERLGAEIARLLAEYEEHLSALQFRKAAFA
                     LRALWSAGNSYLEEKAPWQQIKTDQDAAALTLRTAMNLIDLYAVVSAPVIPFTCETLRS
                     VFATGAGGDGERTDGWVTAEAARSLDSVPAGTDFTVPPVLFAKITDDDLEGFRQRFGGE
                     AG"
     gene            18836..19999
                     /locus_tag="LC193_RS27160"
                     /old_locus_tag="LC193_27160"
     CDS             18836..19999
                     /EC_number="2.7.1.170"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018381518.1"
                     /locus_tag="LC193_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27160"
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="WP_226078011.1"
                     /transl_table=11
                     /translation="MLSGTSLDAVDAAVAEFAFDGHDLVLRPAGLHTEPYPARLREELA
                     ACLPPAATTFEQVCRLDTRLGQFFGRVAARANDGLARGRADLVASHGQTVYHWVAGGRA
                     RGTLQLGAAAWIAEATGLPVVSDLRTRDIAGGGQGAPLAATLDALLLLTGTDGTGRGAL
                     NLGGIANITVGDAAGGIVAYDIGPANALIDAVAAEASGGAERMDTGGARAARGTADPGL
                     LALLLAEPYYRLPPPKSTGKELFHAGYLAGLLRRLGRRPADDDLAATVTELTARLVGAA
                     CRTHGLTELVVSGGGVRNPVLMDRVRALAAPARVVPVERFGLPGQAKEAYLFALLGFLT
                     AHGLAGSVPSATGAAAPALLGSLTPGAGPLVLPRPRAEPPRRLRVVP"
     gene            complement(20028..22202)
                     /locus_tag="LC193_RS27165"
                     /old_locus_tag="LC193_27165"
     CDS             complement(20028..22202)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656171.1"
                     /locus_tag="LC193_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27165"
                     /product="putative bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="WP_404819496.1"
                     /transl_table=11
                     /translation="MTSSPPGPTGHHRTGTGQEPSAGLRRFTALWARAVHPRALTSLPV
                     PEFEAVLLPLARRLADALGAARFDPAPGRAVGAALVDARCPADALPSVLGVIDSGLVAH
                     CGPPPGPDRPAPEELRARCTRLQHAVSAGFARALQERTRTEQEAVSRAALAARTEMTDA
                     LHESEARFRAVFKGAALGIGIADMDGTIIDVNDALGQMFGSTEEQVRSRNVLEWASPDD
                     RPEAWRMLEELMRGTRDHYQVEKSYHRSDGTMLWTNLTVSLLRDPAGGPRYLLAMMEDV
                     TERRLLTLRLRYQATHDALTDLPNRSLFFERLEQALDRGGQGTARIGLCYLDLDGFKAV
                     NDSLGHAVGDQLLIAVAERLQRCASGPGQLLARIGGDEFVALVIDPPDRRAVTDLAERA
                     LDALSSPVEVGGRELLVRASIGVVEGPARHLTSAEVLRSADITMYRAKAEGGNRYAVAD
                     PDSDARAISRHHLTHHLPAALKGCEFFIEYQPLVRMGDGSLEGAEALVRWSHPRHGVLG
                     PDRFIPLAEHTGLIVPLGQWVLKEAVRQACQWQVRGIGGTRPLKVNVNLSPRQLHHPDL
                     VDDTVTVLEESGLDPSALCLEVTETAMVSADESELRPLRELAEYGVGIALDDFGTGYSN
                     LANLRRLPASTLKLDRSFTQGLQRDPADPVDLKIVEGIVSLAHTLQLSVTVEGVETSVQ
                     AEQLRDLGCDSAQGWYYARPGPPERLPEAV"
     misc_feature    complement(22170..22184)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     misc_feature    22311..22324
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.58"
                     /tool="antismash"
     misc_feature    complement(22688..22705)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.77"
                     /tool="antismash"
     misc_feature    complement(22724..22742)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.26"
                     /tool="antismash"
     gene            complement(22800..24047)
                     /locus_tag="LC193_RS27170"
                     /old_locus_tag="LC193_27170"
     CDS             complement(22800..24047)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019432665.1"
                     /locus_tag="LC193_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_27170"
                     /product="transglycosylase family protein"
                     /protein_id="WP_226078012.1"
                     /transl_table=11
                     /translation="MTSRGRHRRYRPSAVSRASLTVTASGAGLAIPLLGAGVAAAAPVD
                     TWEEVAECESSGRWDINTGNGFFGGLQFQQSTWESYGGTAYAPRADLATRDQQIAVAEE
                     VLDGQGPRAWPACAAEAGLTRDGVRPDIAPADAPGPAPTAERAPAAEESATRTSTPTGR
                     GERAGDLYEVVRGDTLSGIASAKDVRGGWQSLYELNRRTVGSDPDLILPGQRLALRAPA
                     DGGTEEQEREAAEPREEPAAEEPREAPEPEPAPEPEPEPEPEPAEQPQGEREEQPAEAA
                     PAYTAPVSAGTGTAYRSSGGSWSLGYHTGVDFPVPTGTSVKSVAAGTVVSAGWAGSFGY
                     EVIVRHPDGHYSQYAHLSAISVSEGQSVTTGRQVGRAGSTGNSSGPHLHFEIRTGEGFG
                     SDVDPVAYLRGHGVSL"
ORIGIN
        1 gtggttgtac tcccgctcga ccagacccga ctgcggatcc ggatggtggt aggtgaccgt
       61 gccggcctcg cgcagcagcg cgggcgccac gcccaactcc tcgacggtgc gccgcgtggc
      121 ggccaggaac ggcggctcgc ccgggtacgg gtggccgcag cacgtgttcg accagacgcc
      181 gggggagtgg tacttcccca gcgcgcggcg ctggagcagc agccgccccg cggcgtcgaa
      241 caggaagacg gagaaggcac ggtgcagtct tcccggcgcc tggtgtgcgg acagcttctc
      301 cgcggtcccc accgtcctgc cgtcctcgtc gacgagttcg agcatgacct gatccgccat
      361 ggcgtcggtg ctctgcggca tgcgtacctc tcccggggcc tcgcggccgt cgttacccgg
      421 cctcgcggcc ctaccctctg cccgccaccg cgggcagagg accagtgtgc cgcaccgggt
      481 cagtggcaca gaccgggctc atgggcggcg tgccccgagg gttcgagctg gaacgtgcag
      541 tgcgcgacgt cgaagtgctc gcccaggcag ccctgcaacg cgtgcagcat ctcctcgtgg
      601 ccgaccgcgt ccagcgtctc gcgcgccacc acgacgtggg cggacagcgc gggcataccg
      661 gaggtgatgg tccacacgtg caggtcatgc agcccctcga cgcccggcag tcccagcacg
      721 tggtccctga cctcggcgat ccgcacgtcc ttcggcgcgg tttcgaggag cacgtcgatc
      781 gcctcgcgcg ccagcctgac cgcgcgcggc acgatcagga gggcgatcag cagggaggcg
      841 accgggtccg cggcctgcca gccggtgaac atgatcacga gggcggcggc gatcaccgcg
      901 accgacccca gggcgtccgc cgccacttcg aggaaggcgc cgcgcacatt caggctctcc
      961 cgctggccgc gcatcagcag cgcgagcgac acgcagttga gcagcaggcc ggcgacgccg
     1021 aacacgaccg tcagcccgcc gggcacctcg gccggctccc gcagccggcc gatggcctcg
     1081 atcaggatgt acccgcccac gcccagcagc agcacgcagt tcgccagggc cgccaggatc
     1141 tcgacgcggg cgaagccgaa cgtccgccgg tcgctgcgca ccggccggtt ggccacgtgg
     1201 atggcgacca gggccatgcc gatgccgacg gcgtccgtgg cgacgtggcc ggcgtcggcg
     1261 agcagggcga gcgagccggt cagcgcggcg cccaccagct cggccaccag cagaacgcag
     1321 gcgatggcga gggccgcggt gagccgcccg cggtgcgccg cgcccgcggt gccgccccgc
     1381 ggcggcccgc cgtggtggtg tccggctccc atcgaagcgc ccccttgttt cgtcggcact
     1441 ccacagtgaa ctacgggagg ggggtatctg gcaacgcggc actgaacacc gttgtcatgt
     1501 gctctgacct gctgattcct gtcccggccc gccgggtgcg cgccgggtgc tccgacgtgc
     1561 ggcaatggtg gagagctaca ggccgccgtg cgtgcggcgc cagccctccc aggccgagga
     1621 gaccatgtcg ggcagtccgc ggcgggccgt gaaccccagg cgctcgcgag ccagttcgac
     1681 cgaggccacc acccgtgccg ggtcccccgg ccgccgcccg gcgacgcgcg ggggtccggc
     1741 gaacccggtg acgtccgcga ccagggcggc cagctcccgc accgaggcgc cgcggcccgt
     1801 gccgacgttc accgtgaggt cggcgcccgg cgcggcgtcg gccaggtggc gggcggcgag
     1861 caggtgcgcg tcggcgaggt cggccacgtg cacgtagtcg cgcacgcagg tgccgtccgg
     1921 cgtggggtag tcggcgccga agatctccgg gggccgcccg gccgcgatcc gttcgaagaa
     1981 catggggacg acgttggccg ccccggcgtc cgccagctcg gggcgggtcg ccccggccac
     2041 gttgaagtag cgcaggcacg ccgtcgcgat gccgtgcgcc cgcccggcgg cccgcaccag
     2101 ccactcgccg gccagcttcg tctccccgta ggggctcagc gggcggcagg gcgtgtcctc
     2161 ggtgaccgtg ccggtctccg gcgtgccgta cacggcggcc gacgaggaga agacgaactc
     2221 ccgcaccccg gccgccacca ccgcgtcgag caggacggtc aggccgtgga cgttggaccg
     2281 gtagtacgcg agcggctcgg ccaccgactc ggccacctgc ttcttcgcgg ccaggtgcac
     2341 caccccgcgc accccgtgct cggccagcgt cgtgtcgagc agcccccggt cgaggattga
     2401 gccgcgcacc agcggcacgt cagccggcag ccggccggcg cggcccgagg agaggtcgtc
     2461 gaggaccacc acgcgttcgc ccgcggcgcg catggtctcc acgacgtgtg ccccgatgta
     2521 cccggcaccc ccggtgatca gccagctcat gagggcaccc taaccccggg ggaacccgtc
     2581 ggacgccggg ggcgcgggcc cgccccggcc ccgcgctctc ctgtcgcccg ccgtgtcggt
     2641 ggcgtcacat agggtcgcgg tgaccgccgc gcggggcgcc ggacatgaac tcggggtttc
     2701 ttggggtcaa cgccattctt tccgtgtggt ggtcatcaga taatctctgc cgacgtgcag
     2761 ccgtgccgac ggttctgccc caaggagtga gtcacctgtc gaccgccatc ctcaccggtc
     2821 cgcccccgcc cgggtcgccc ctcgaaagcg acctgcgcga gctgggcttc tccgtcctgg
     2881 tcctggacac ggcggccggc ctggcggcgg aactcgcggc cgtcccgccc ggccgccgcg
     2941 tcgcggtcgt cgacccgcgc ttcgtcggcc acctgcacag cctccgcctc ggcctcaccg
     3001 atccccggtt cccggtcgcg gccctgccgg gcgccgtgac cgcgctcccc gaggggcggg
     3061 ccgccctggc cgccgcggtg gccgaggccg caccggcgcc cgggccgccg accggaacgc
     3121 acggccgcgc cgtggccgcg ccgccggccg gcacctgcct ccccgaagag ctggccgcac
     3181 gcctcaccgc cgcgggctcg ccgccgcacc ggcccgaact cggcaccctc gtcgccgccg
     3241 tgcccgagac ggcggagcag cgggccgggg ccgaggcgga cgtggccgcc gtcgacgagg
     3301 aggccgtgcg gctgcgctcc gcggtcaagg cgagggacgg cttcttcacc acccacttcg
     3361 tgagccccta ctcccgccac ctcgcacgct ggtgcgcccg ccgcggcctc acaccgaacc
     3421 aggtcacgac ggcctcgctc gtcaccgccc tgatcgccgc cggctgcgcc gccaccggga
     3481 ccaggggcgg cttcgtcgcc gcgggcctgc tcctgctgct ctcgttcgtc ctcgactgcg
     3541 ccgacggcca gctggcccgc tacgccctgc ggtactccac gctcggcgcg tggctcgacg
     3601 ccacgttcga ccgggccaag gagtacgcct actacgccgg cctggcgctc ggcgccgccc
     3661 gcgggggcga cgacgtgtgg gccctcgcgc tcggcgccat ggtcctccag acctgccggc
     3721 acatcgtgga cttcgcgttc aacgaggcgc acccgcccgc tcccggcggc gcggccggcg
     3781 ccaccgccct gtccgggcgc ctcgaccgga tcggctggac ggtctggctg cgccgcatga
     3841 tcgtgctgcc catcggtgaa cgctgggcgc tgatcgccct gctcaccgcg ttcaccacgc
     3901 cccgcgcgac cttcgtcgtc ctgctcgtgg cagccggctt cgccgcctgc tacaccaccg
     3961 cgggccgcct gctgcgctcg cgccgcctgc ccggcggcgg gcccggcacg gccgccgcgc
     4021 tcggcggcct cgcggacaac ggcccgctcg ccgaggccgc ggcccgcgtc cgcccgcgcc
     4081 ccgcgggcag cgcgttcacc gcgccgctgt gggccgcggc cggcaccgcg ctgctcgtcg
     4141 gcctgctgct ggtgccggga gtggccggcg gctgggcggc cgtcgcggcg gccctcgcct
     4201 acgccgtgtg cgccgggcgc gcgacggcgg cgccgctggt caggccgttc gactgggtgc
     4261 tgccgccgct gttccgcggc ggcgagtacc tcgcgatcct cgtgctcgcc gcggaatcgg
     4321 gggtaaacgg agcgttgccg gcggctttct gcctggtggc cgcctgcgcc taccatcact
     4381 acgacacggt gtaccgcctc aggggcggcg ccggggcacc cccccgccgg ctggtcctgg
     4441 tcaccggcgg gcacgagggg cgggtcctgg tggtctccgc cgccgccgcc ctgtgggccg
     4501 gcggacaggg cttcaccgtc gcgctcgcgg tccttggcgg ggccacggcg ttcctggtgc
     4561 ttggcgagag catccgcttc tggatctcgg cccaggcacc ggccgtacac gacgaaacag
     4621 gagaacccgc atgatcggcc tcgtgctggc cgccggcgcc ggacggcgtc ttcgccccta
     4681 caccgacacc ctgcccaagg cactggtgcc ggtcatcgac gcggaaggcg agaacggcag
     4741 aacggtcctc gacctcaccc tggcgaactt cgccgaggtc ggtctcaccg aggcggccat
     4801 cgtcgtcggc taccggaagg aggccgtgta cgagcgcaag gacgccctgg agcgcagcta
     4861 cggggtgcgg ctgaccctca tcgacaacga ccgggccgag gagtggaaca acgcctactc
     4921 cctgtggtgc gcccgcgagg tcatcgagga gggcgtgatc cttgccaacg gcgacaccgt
     4981 ccaccccccg tcggtggaac gcaccctgct ggccgcgcag gcggcgggcg gcccgggggc
     5041 ggggacgggg cgcgtcatcc tggcgctcga caccgtgaag aagctggccg acgaggagat
     5101 gaaggtcgtc gccgacccgg agaagggcgt acggcgcatc accaagctga tggaccccgc
     5161 cgaggcgacc ggcgagtaca tcggcgtcac gctcatcgag ccgggggccg cggccccgct
     5221 ggccgacgcg ctgcgcacca cgttcgaacg cgacccgcag ctgtactacg aggacggcta
     5281 ccaggagctg gtccaccgcg gcttccgcat cgacaccgcc gccatcgggg acgtcagctg
     5341 ggtcgagatc gacaaccacg acgacctcgc gcgagggcgg gagatcgcgt gccggtactg
     5401 acccgcctca tcccgtcccc cgtctcggtc gacatcatgg cgggggccct ggacaacctg
     5461 gcgggcctgc ttgccgacca gcggatctcc tcatcggggc ggctcgccgt cgcgatcagc
     5521 aacggctcgg gcgcggccct gcgcgaccgg ctggccccgg ccctgccggg cgccgactgg
     5581 tacgaggtcg ccgggggcac catcgacgcc gcggtgcagc tggccgacgc gatgcgccca
     5641 ggccactacg acgccgtggt ggggctgggc ggcggcaaga tcatcgacgc ggcgaaatac
     5701 gccgccgccc gggtcgggct gcccatggtg gccgtggcca ccaacctgtc gcacgacggc
     5761 atctgctccc cggtgtccac gctcgacaac gacgcgggac gcggctccta cggcgtgccc
     5821 acgccgatcg ccctggtcat cgacctcgac gtgatccgcc gcgcgcccgt gcgctacgtg
     5881 cgctccggca tcggggacgc cgtgtccaac atctcggcga tcgccgactg ggagctgtcc
     5941 caccgcgaga ccggggagca gatcgacggc ctggccgccg ccatggccag gcaggcgggc
     6001 gaggccgtgc tgcggcaccc gggcgactgc ggcgacgacg cgttcctgac cgtgctgtcc
     6061 gaggcgctcg tgctctccgg tatcgcgatg tccatcgccg gccacacccg gccgtcctcc
     6121 ggtgcctgcc acgagatctc gcacgccctc gacgtactcc acccgcggcg ttccgcgccg
     6181 cacggggagc aggtcgggct cggggccgcg ttcgcgatgc acctgcgcgg ggccgtcgac
     6241 cagtgcggcc tgatcgccga cacgctgcgc cgccacgggc tgcccgtgct gccgggccac
     6301 atcgggttca gcaccgacga attcgtggcc gcggtggcgt tcgccccgca gaccaggccc
     6361 ggccgctaca ccattctcga acacctcgac ctgtccaccg accagatcag ggacgcgtac
     6421 gcggactatg tcaaaaccat cggtagctga actccggccg gtcgtgcacc ccccgggggt
     6481 gaaggaccgg cgcagcggtg agcactgggc cgggcgcctg tacatgcggg agatctcgct
     6541 gcgctggacc cggcacctgg tgaacacccg gatcagcccg aaccagctca cctacctgat
     6601 ggtcgtcgcc ggcgtcgcgg ccggcgccgc gctgctggtc cccggcctcg ccggggcggt
     6661 ggccgcggcg ctgctcatcc agctctacct cctgctcgac tgcgtcgacg gcgaggtcgc
     6721 gcgctggcgc ggccagacct ccatcaccgg tgtctacctg gaccgggtcg gccactacct
     6781 ggccgaggcg gcgctcctgg tgggcttcgg ggtgcgtgcc gccgacgtgt tcgccgccga
     6841 ggaggccgcc ccgaactggc tctgggcgtt cctcggcacg ctcgccgcgc tcggcgccat
     6901 cctgatcaag gccgagaccg acctggtcga tgtcgcgcgg acccgcggcg ggctcccggc
     6961 ggcccgggac gacgcggcca taccccgctc ctcggggctc gcgctggcgc gcagagccgc
     7021 cgcggccctg aagttccacc ggctggtcgg cggcgtcgag gcgtcgctgc tgatcctcct
     7081 ggtggcggta ctcgacctgg ccaggggtga cctgttcttc acccgcctcg gcgtggccct
     7141 gctggccgcc gtcgcgctcg tgcagactct cctgcacctg gtgtccgtcc tggcgtcgag
     7201 caggctgagg tgagtgtggt gggtacggcg cagctcagac tcggcgcggt catcctgacc
     7261 atgggcgacc ggcccgaggc gttgcgggcg ctgctcgact cggtggccgc acaggacggc
     7321 gcggccatcg acgtggtcgt cgtcggcaac ggtgcccggc tgcccggcct gccacccggc
     7381 gtgcgcagtc tcgaactgcc gcagaacctc ggcatccccg gcgggcgcaa cgtcggcatc
     7441 gaggcgttcg gccccggggg cagcgaggtc gacgtgctgc tgtttctgga cgacgatggt
     7501 cgacttccag acaaaaacgt ggcagagacg gttcgggccg ccttcgaggc cgatccccag
     7561 ctcggcatcg tcagcttccg catcaccgat cccgagagcg gtaccacgca acgccggcac
     7621 gtgccgcggc tgcgcgcctc cgacccgttg cgctcctcgc gggtcaccac cttcctcggg
     7681 ggcgcgaacg ccgtgcgcac ccacgtcttc cagcaggtcg ggggcctgcc ggacaacttc
     7741 ttctacgcgc acgaggagac cgacctggcc tggcgggcgc tcgacgccgg ctggcacatc
     7801 gactaccgcg ccgacctcgt gctgcaccac cccgcgaccg cgccgtcccg gcacgccgtg
     7861 taccaccgca tgatcgccag gaaccgggtg tggctggccc gccgcaacct gcccctgccc
     7921 ctggtgcccg tctacctcat gaactggctg ctgctgaccc tgctgcgcag gccgtcgcgg
     7981 ccggcgctcg ccgcgtggtt cggcggcttc gtggaaggct ggcggacgcc ctgcgggccc
     8041 cgcaggccga tgcgttggcg tacggtatgg cgcctgaccc ggctcggacg acctcctgtc
     8101 atctgacaag ctcgggtctg agaacatcca gtagccgccg caccgcggca tcttccagct
     8161 tgtgccctgc gaggacgaga gttcaagtga gtgagaccac gcacgacagt gcgccccccc
     8221 gtgatgtacc actggccgaa ctcgcggccc gtcacggcct gtccgtcagt ggtgcccggc
     8281 cctccctgcc ggggtacgtg cggcagctgt gggggcggcg gcagttcata gtcgccttct
     8341 cccaggcgaa gctgtccgcc cagtacagcc aggccaagct cggccagatc tggcaggtgc
     8401 tcaccccgct gctcaacgcg ctggtgtact acctgatctt cgggctgctg ctcgacgggc
     8461 gcggcgacat ggagaacgac gagtacgtcc cgttcctggt gaccggggtc ttcgtcttca
     8521 ccttcacgca gaactccgtg atgtcgggag tgaagtccat ctcgggcaac ctgggcctgg
     8581 tgcgggccct gcacttcccg cgcgcctcgc tgccgatctc gctgtccctc cagcagctcc
     8641 agcagctgct gttctcgatg gtgatcctgt tcgccatcgt ggtcgcgttc gggcacttcc
     8701 ccgagttcaa ctggctgctg gtcatccccg cgctgctgct gcaactggtc ttcaacaccg
     8761 gtctcgccct gttcttcgcc cggctgggca gcgcgacccc cgacctggcc cagctgatgc
     8821 cgttcgtgct gcgcacctgg atgtacgcct ccggagtgat gttccccctg gcctacatgg
     8881 tggagaagcg cgccgagtgg ccgctctggg tcgcggacgt cctcgcggcc aacccggcgg
     8941 ccgtgtacat ggacctggtg cgctacgcgc tcatcgacgg gacctaccgg gacagcatcg
     9001 agccggtcac ctggctcttc gggctcggct gggcgctcgt cgtcggcatc ggcggcttcg
     9061 tgtacttctg gaaggcggag gagcggtacg gtcgtggctg aacaggacat ctccaccgga
     9121 ggaccgggcg ggcagcgcgt gcccacggtc atcgccgacg ggctccacat cgtctaccgc
     9181 gtccacggcg gcggcggccg gggcaccgcc accgccgcgc tgcgccggat ggtgcgccgc
     9241 gagcgcggct tcaagatgcg cgaggtgcac gcggtgcgcg gggtcagctt cgtcgcctac
     9301 cgcggcgagg ccatcggcct catcggcagc aacggctcgg gcaagtcgac cctgctgcgc
     9361 gcgatcgcgg gcctgctgcc gcccgagcgc ggcaaggtct acaccgacgg gcagccctcg
     9421 ttgctcggcg tcaacgccgc cctgatgaac gacctcaccg gcgagcgcaa cgtcatcctc
     9481 ggtggcctgg ccatgggcat gtccagggac gagatcaagg gccgctacca ggagatcgtc
     9541 gacttctccg gcatcaacga gaagggcgac ttcatcagcc tgccgatgcg cacctactcc
     9601 tccggcatgc aggccaggct gcggttctcc atcgccgtgg ccaaggagca cgacgtgctc
     9661 atgatcgacg aggcgctggc caccggcgac aagaagttcc agcgccgctc ggaggccaag
     9721 gtgcgcgaga tgcgcgccga ggccggcacc gtcttcctcg tcagccacaa caacaagtcg
     9781 atcagggaca cctgcgaccg ggtgctgtgg ctggagaagg gtgaactggt catggacggg
     9841 cccaccgacc aggtgctcaa ggcgtacgag gaagagaccg gcaagtaggc cgggcacgcg
     9901 gtcaccgccc gtgccggaac gcgtgtccgg cacgggcgat tgtccgacca tagggtaaaa
     9961 gagtaggcat gagggcaatg gtgacgacgg accgcccgtg ctgacggccg agcacagcga
    10021 cgccgggccg gacggcggcc gagccgtcct ggccaaggcc gcgcacgaga acttccctgt
    10081 ggcgccccgc ttcctgccgg cggcctggcg cgaggacctg atggccctct acggcttcgc
    10141 ccgcctcgtc gacgacatcg gcgacggcga cctggccccg ggcggcgccg acgcggcgca
    10201 cctgggcgtc gacccggcgg gcgccgcgga ccgcctgctc ctgctcgacg ccgtcgaggc
    10261 cgacctccgc cgcgtcttcg ccagcgccac cggcggcacc ccgccccggc acccgctgct
    10321 gcgcgaactg atccccaccg tgcggcgctc cgggctcgcc cccgggccgt tcctcgacct
    10381 catcgaggcc aaccgcgtcg accagcgcgt ccgccgctac gccacgtacg cggacctcct
    10441 cggctactgc gaactctccg ccaaccccgt cggccgcctc gtgctggccg tcaccggcac
    10501 cgccacgccc gagcggatcc gccgctccga cgccgtgtgc accgcgctcc agctgatcga
    10561 gcacctccag gacgtcgcgg aggacctcgc gagggaccgg atctaccttc ccgccgatgt
    10621 catggaccgc ttctttgtga ccgaagccga cctcgccgcg cccaccgcga acgcttccgt
    10681 gcgcaccctg gtggcatacc tgaccgaccg ggcacgtagg ctgctcgaag agggcgcgcc
    10741 cctgatgtcc ggagtgtccg ggcggctgcg attgctgctc gccgggttca tcggcggcgg
    10801 ccacgccgcc gcgcgggcca tcgaggacgc cgggtacgac gtcctggccg ggccaccgcg
    10861 ggcgtccaag ggcggactgc tgtacgcggc ggccacgaca ctgcgaagag gaacgtgagc
    10921 ttcgaggccg tgaccacccg ttcacccctg cctcctgccg tcgtcgccgc ctaccggtac
    10981 tgcgagagca tcgccgagca gcacgcgcgg aacttcagct acggcgcccg cctcgtgccc
    11041 gcgcccaagc ggcgggccct cacggcggtg tacgccttcg cccgccgcgt cgacgacatc
    11101 ggcgacggcg acctggcacc cgaggccaag gaggaacggc tcgccgcggg ccgcgccatg
    11161 ctggcccggg tccgcgacgg cgcggtgccc gaggacgaca ccgaccccgt cgcggtcgcc
    11221 ctcgcgcacg cgggccgccg cttccccatc ccgctcgacg cgctcgacga gctgatcgac
    11281 ggcgtcctga tggacgtgcg cggccacacc tacgagacgt gggaggacct gcggctctac
    11341 tgcacccgcg tggccggcac catcggccgc ctctccctgg gcgtcttcgg cgtcaggccc
    11401 ggcgcgcccg gcacggaacg cgccgaggag tacgccgaca ccctgggcct ggccctccag
    11461 ctcacgaaca tccttcgcga cgtccgcgag gacgccgagc gcggtcgcgt ctacctgccc
    11521 gccgaggacc tgcggaagtt cggctgcccc gaggggcccg acgtggtcgc ccccggccgg
    11581 gacgccgact tcaccgggct gatccgcttc gaggtccgca gggcccgcga gctgttcgtc
    11641 cggggctccc ggctgctgcc cctgctcgac cgccgctccg gcgcctgcgt caccaccatg
    11701 gccggcatct accaccggct cctggaccgc atcgaggccg agccgcgcgc cgtgctgcgc
    11761 ggtcgcgtca ccctgcccgc gggccacaag gcactcgtcg ccgcccgcgg cctcaccggc
    11821 ctcgacgcac gccgcgccgc ccggcgggag ccgctgtgac cagcacgcgg cgccccgggc
    11881 acaccatcgt gatcgggggc ggcctcgccg gtaccaccgc ggcgctcgcg ctcgccgacg
    11941 ccgggcgggc cgtcacgctg gtcgagtcac ggccgcggct gggcgggctc gcgttctcct
    12001 tccgccgcga ctcgccggcc ggaccgctca ccgtcgacaa cggccagcac gtctacctgc
    12061 gctgctgcac cgcctaccgc ggcttcctcc agcgggtggg ggccgccgcg ctcgccccgc
    12121 tgcaaccgcg cctcgacgtg cccgtgctcg acgccgccac cggccgcctc ggccgcatcc
    12181 ggcgcaccgg gctgcccgtt ccgctgcacc tggccggcag cctcgcccgc tacccgcacc
    12241 tctccccggg ggaacgcgcc gccgcggccc gcgccacgct cgcgctgcgc gccctcgacc
    12301 cggacgaccc gcggctggac cggcaggact tcgcggcctg gctgcgccgg cacggccaga
    12361 ccgaccgcgc cgtggccgcg ctgtgggacc tcatcggcgt cgcgaccctc aacgcccgcg
    12421 ccggcgacgt ctcgctcggt cttgccgcga tggtcttccg caccggcctg ctcaccgcgc
    12481 cgggcgcggc cgacctcggc atcccgcggg caccgctcgg cgagctgcac gacaccaggg
    12541 ccagggccgc cctggaccgg gcgggcgtca cgaccctgct gagcacgcgc gcccgccgcc
    12601 tcgcccccgc ccgcggcggc ggctggcacg tcaccgtcgc cgcgccgcgc ggcctgccgc
    12661 gggccgcgca cgagctgacg gccgactccg tcgtgctggc cgcgccccac gacgtcgccg
    12721 cccgcctgct gcccgcgggc gccatgaccg acccgggcgg cctgcggcac atcggcaccg
    12781 cgccgatcct caacgtccat gtcgtctacg accggcaggt cctgcgccgc ccgttcctcg
    12841 ccgcgctcgg cagccccgtg cagtggatct tcgaccgcgg cggccccgcg gggctcggcg
    12901 cgccggggcc cgggcggccc cagtacctcg cgctgtcgca gtcggcggcg ggcgaggaga
    12961 tccagctgcc cacggacgtg ctgcgcaagc gctacctgcc ggaactggcc aggctgctgc
    13021 cgcgtgcggc gcgggcgcgg gtcaccgatt tcttcgtcac ccgggagcgc gccgccacct
    13081 tcgcgccggc ccccggggtc gggcggctgc ggcccgggcc gcggacccgg gccgccggcc
    13141 tctacctggc cggcgcgtgg acggccacgg ggtggcccgc gacgatggag ggcgccgtcc
    13201 gcagcggcca cgcggcggcc agggcggtgc tcgccggcgg cccggccccc gaacacacca
    13261 ctgctgagga gagcgcgtga accagccagc ccatacggac ggcgccgtac cggcgctgct
    13321 ggaacgcggg cgggccctgg ccgcgcccgc cctgcgggag gccgtcggcc ggctcgcccc
    13381 gccgatgaac accgtcgccg cctaccactt cggctggatc gacgccgacg gcaggcccgc
    13441 cgcgagcgac agcggcaagg ccatcaggcc cgcgctcgcc ctgctgtccg cggaggccgc
    13501 gggcgccgcg cccgagaccg gcgtgcccgg cgccgtcgcg gtcgaactgg tgcacaactt
    13561 ctcgttgctg cacgacgacc tcatggacgg cgacgagcag cgcagacacc gcgacaccgt
    13621 gtggaaggtg cacggccccg cgcaggccat cctggtcggc gacgccctct tcgcgctggc
    13681 caacgaggtg atcctcgccc ccggcaccgc cggcgccgcc cgcgcggccc ggcggctcgc
    13741 cgcggccagc cgccggctcg tcgacggcca ggcccaggac atcgccttcg agcacaggga
    13801 gcacgtcacc gtcgccgagt gcctggagat ggagggcaac aagaccggcg cgctgctggc
    13861 ctgcgccgcc tccatcggcg ccatcctggg cggcgccgac gacgccctgg ccgagagcct
    13921 cgaactgtac ggccagcacc tcggcctggc cttccaggcc gtcgacgacc tgctcggcat
    13981 ctggggcgac ccgcgcagca cgggcaagcg cacctggagc gacctgcggc agcgcaagaa
    14041 gtcgctgccc gtggtggcgg cgcaggccgc gcggggcccg gcggccgaac ggctgacggc
    14101 gctgctcacg gccgacgcga agaagacgca ggaggagttc gacgacttcg acgaggcgga
    14161 gttcgccacc cgcgcggcgc tgatcgagga ggccggcggc cgggtctgga ccgagggcga
    14221 ggcgcgccgc cagtacgacg cggccgtcgc cgccctgcac cgcgtcgacg tgcccgcccc
    14281 cgtcagggag cggctgaccg cgctcgccga cttcgtcgtg gtccgccaga agtgacgcac
    14341 tccgcccgtt cggccgcgcg ggccggtcgg cccgggccct gagcggggcg ccgcacggcc
    14401 gcccccgttc cgccgcccgt gcggcggcag gtccacgtgc cgcacgccgg ccaggccgac
    14461 ggtcgtccct ccgcgttccc ggttcgcggc cttgccgaag ccgagtgccc gcacgcgccg
    14521 ggtgccccca gcggcaccgc gccccgggcg gcccgccgcc ggtgatcgag cccgccccca
    14581 tggcacggcc ggccggtacg cgggcccatg ggcgaggatg aacacatgga cgaagacacg
    14641 ctgttcccgc gggaacgggt cgagatcgcc ccgggcgccg tgcacctccc cggctggctc
    14701 ggccgggagc gctccgcgga cctgctcgcc gcctgccgcg cgtgggccct gccgcccgcc
    14761 gggctgcgca cggtcctcat gccgaacggc ggccggatgt ccgtcgagca ggtcagtctc
    14821 ggctggcact ggtaccccta cggctacgcc cgcaccgtcg tcgacggcga cggcgcgccg
    14881 gtcaagccgt tccccgcctg gctcggcgcc tgggccgcgc gggcggtcgc cgacgcgggc
    14941 ccgggcgtgg acgccgccgc gtacgccccc gccgccctcc cgttcgacat cgccctcgtc
    15001 aacttctacg gcccggacgc ccggatgggc atgcaccgcg acagcgacga acgggtgtcg
    15061 gcgcccgtgg tgtccttcag cctcggcgac acgtgcgtct tccggttcgg cacccccgag
    15121 gggcgcggcc gcccgtggca ggacatcgag ctgcgcagcg gcgacgcgtt cgtcttcggc
    15181 gggccgtccc ggctcgccta ccacggcgtg ccgcgcaccc ggccgggcag cgcgccggcc
    15241 ggcctcgggc tcagcggcag gctcaacgtc actgtgcgtg tctccggatt cggcgccccg
    15301 gaggacgggg tcccccaggc gtgaagccgg tcaaggccgg gcccggcgca ttcactcgtt
    15361 gggagctggc gtggggtggc gattgccgga actgtgcccg ttcgcctacc tgttgacgca
    15421 tagcgtggcc ttgcacccac ttgacccgcc cgataaggac acccatgcct gagcagccac
    15481 gccacggggc aggcgcgccc cgccacagtc ggctggcctt cggcgagccg ggcggcgggg
    15541 agccgggaac cagacgccgc ctgctgcgcc tggccgtgct ccccgccgtg ctggtcgccg
    15601 tgatcgcgac cgcggccctc gtctacgtgc tggcccgggg cggcccgggg accgggcggg
    15661 gcagctgccc cgtctggacg gtgctcgcca cggccctggt gctggtctgc gccgtcgtcg
    15721 ccggagcggc gatccgcgcc gccggcgagg cacgggccca cggcgcgcgg ctgaccggcc
    15781 tgcgccgcca ggcggcccgc ggacgtgtgg aactccaggc gctgctggtc aaggtggagc
    15841 gcggcgaacg catcaagccg ccggagggcc cggcccccgc ggagcccgcc gaggaccagc
    15901 tcgatcagct gcggcacgag atcgaggccg cgcagcacgc cgccgagtcc gccgtcttcc
    15961 aagcatcgtc cctggtcaga ggcggggagg acgagcgcgt cgaggtgttc gtcagcctgg
    16021 cgcggcggtt gcagtcgttc gtgcaccggc agatcgagta cctggaggag ctggaggagg
    16081 aggtcgagga cccggaactg ctgaaaggcc tcttccacgt cgaccacctg gccacccgcg
    16141 tgcgccggca cgccgagaat ctcgccgtgc tcggcggcgc ggtgccgcgc cgccagtgga
    16201 gccgcccggt cgggatgtcg gaggtgctgc gttcctgcgt cgccgaggtc gagcactact
    16261 cccgggtcaa gctggtgcca ccgatcgagg gcagtgtgcg cggtcacgcc gtcgccgacg
    16321 tcatccacct gctggccgaa ctggtcgaga acgccacgga gttctcggcc ccgcagaccc
    16381 aggtgctcct gcgcgtgcag cgcgtcgccg ccgggatcgc catcgaggtc gaggaccggg
    16441 gcctgggcat gaccccggcg gagcaggtgc ggatgaacgc ggtgctggcg ggcgccgagc
    16501 gggccgacgt gaccgacctg cttgaggacg gccgggtggg cctgttcgtc gtcgccaccc
    16561 tcgcgcggcg ccacgacatc gtcgtgcagc tccagagcaa cgtctacggc ggcgtgcagg
    16621 ccgttctcat gctgccgtcc gacctgctgg gcgacgactc cgatgccggc cacgtgcggg
    16681 ggcgtgccat ccgggcgatc gaggcggcac cgcgggacgg cctgccgcgc gcgcccctga
    16741 cgcgccgtcc ttcgctggtg ccggggccgg gcggggacga ggaggacccg gcccccgggc
    16801 tgatcgccgc gtcgcccggg cccgcgggac ggccggagga cgccgaggcc tgaccggccg
    16861 gcggcgtcct cgggccggtg ccgcggcggg acgccgggcc gcgcggagga ggcccggtgc
    16921 cccgtgggcg ccgtgtcagc cggcttcgcc gccgaagcgc tgcctgaagc cctcaaggtc
    16981 gtcatcggtg atcttggcga acagcaccgg gggcaccgtg aagtccgtcc cggccggcac
    17041 gctgtccagc gaacgcgcgg cctccgccgt cacccagccg tccgtgcgct ccccgtcccc
    17101 tcccgcgccc gtggcgaaca ccgagcgcag cgtctcgcag gtgaacggga tgaccggcgc
    17161 ggagaccacc gcgtagaggt cgatcaggtt catcgcggtg cgcagcgtga gcgcggcggc
    17221 gtcctggtcg gtcttgatct gctgccaggg cgccttctcc tccaggtagg agttgcccgc
    17281 gctccacagc gcgcgcagcg cgaacgccgc cttgcggaac tggagcgccg acaggtgctc
    17341 ctcgtactcg gcgagcagcc gggcgatctc cgcaccgagc cgctcctcgg cctcgccggc
    17401 cgcgtgcccc gcgggcacct ggtcgccgaa gcgcttgcgc gagaacgtca gcacccggtt
    17461 gacgaagttg cccagggtgt cggccaggtc cttgttgacg acggacgcga acagctccca
    17521 ggagaacgac gcgtcgtccg actcgggcgc ccccgcgatc aggaagtacc gccagtagtc
    17581 ggccggcagc acgtcgagcg ccgcgtcggc gaagatgccc cggttctgcg aggtggagaa
    17641 cttgccgccg tagtacgtca gccagttgaa cgacttgacg acgtcgacct tcttccacgg
    17701 ctcccgggtg cccagctggg tggcggggaa catcaccgtg tggaacggca cgttgtcctt
    17761 ggccatgaac tccgtgtacc gcacggacgc gtccgcgtcg taccaccacg cgcgccagtc
    17821 ccgctcctcg cccgcgccgg ccgcgtccgc ccactccttg gtggcgccga tgtagccgat
    17881 cggggcgtcg aaccacacgt agaacacctt gccctcggcc gcgagctcgg gccacacgtc
    17941 cgcggggacc ggcacgcccc actccaggtc gcgcgtgatc gcccggtcgt gcaggccctc
    18001 ggtcagccac ttgcgcgcga tcgaggagga cagcgtcggc cactcctcgc ccgcggcgtc
    18061 cacgaacgcc tccacctcgc gctccagctt cgactggagg aggaacaggt gcgtggtctc
    18121 ccgcacctca agctcggtgc tgccgctcac cgcggagcgc gcctccagca gatccgtcgg
    18181 gtcgagcacg cgggtgcagt tctcgcactg gtcgccgcgc gccgcctcgt agccgcagta
    18241 cgggcacgtg cccacgatgt agcggtcggg caggaagcgg ccgtcggcga gcgagtacac
    18301 ctggcgcgtg gagcgctcct cgatgaaccc gttctcgtgg agccggcgcg cgaagtgctg
    18361 cgtgatctcg atgttctgcg cggacgaggt ccggccgaag tggtcgaaac gcaggccgaa
    18421 cccgtcgtac acggccttct gcgcctcgtg ctgccgcgcg cagaactccg cgacgggcag
    18481 accggccgcc ttggcggcca gctcggcggg cgtgccgtgc tcgtccgtcg cgcagatgta
    18541 cagcacgtcg tgaccgcgcc cgcgcaggta gcgcgcgtac acgtcggcgg ggagcatcga
    18601 gcccaccatg ttccccaggt gcttgatccc gttgatgtag ggcagcgcac tggtgatgag
    18661 gtgtcgggcc atcctcggat gctccaatgg ggtgagaaga gacaatgagc cgtgagtgcc
    18721 gtgagaaggc cgcgaagggc gacggatcac gtttatgggc ttcactcatc ctaccgagcc
    18781 gccggacggc ggccccacca ggttttcccc tgaccggccg tggcgggtga tcggcatgct
    18841 cagcggcacg tcgctggacg ccgtggacgc cgccgtcgcg gagttcgcct tcgacggcca
    18901 tgacctcgtc ctgcggcccg cgggactgca caccgagccc tacccggcgc ggctgcggga
    18961 ggagctggcg gcctgcctgc cgcccgcggc gaccacgttc gaacaggtct gccgcctcga
    19021 cacccggctc ggccagttct tcggccgggt cgccgcccgc gccaacgacg ggctcgcgcg
    19081 cgggcgcgcc gatctcgtgg cctcgcacgg ccagaccgtc taccactggg tggccggcgg
    19141 ccgcgcccgc ggaacgctcc aactcggcgc ggcggcctgg atcgccgagg ccacaggact
    19201 gcccgtggtc tccgacctgc gcacccgcga catcgccggg ggcgggcagg gcgcgccgct
    19261 cgccgcgacg ctcgacgccc tgctcctgct gaccggcacg gacggcacgg ggcgcggtgc
    19321 gctgaacctc ggcggcatcg ccaacatcac ggtcggagac gccgcgggcg gcatcgtcgc
    19381 ctacgacatc ggcccggcga acgcgctgat cgacgcggtg gccgcggagg cgagcggggg
    19441 agccgaacgc atggacaccg gcggagcccg cgccgcgcgc ggcaccgccg accccggcct
    19501 gctcgccctg ctcctcgccg agccctacta ccggctgccg ccgccgaagt cgaccggcaa
    19561 ggagctgttc cacgccgggt acctcgcggg cctgctgcgc cgactcggcc ggcgcccggc
    19621 ggacgacgac ctggccgcca ccgtcaccga gctcaccgcg cgcctggtcg gggccgcctg
    19681 ccgcacgcac gggctcaccg aactggtcgt ctcgggcggc ggggtgcgca acccggtcct
    19741 gatggaccgc gtccgggcgc tcgcggcgcc cgcgcgggtc gttcccgtcg agcggttcgg
    19801 cctgccgggg caggcgaagg aggcgtacct gttcgcgctg ctcggcttcc tcaccgccca
    19861 cggcctggcc ggctccgtgc cctcggccac cggcgcggcg gcgcccgcgc tgctcggctc
    19921 cctcaccccg ggggccggac cgctggtgct gccccggccg cgcgccgagc cgccgcggcg
    19981 actgcgcgtg gtgccctgac ggctccggtc gcgcggcacg gccgggctca gacggcttcc
    20041 ggcaggcgtt ccggcggccc agggcgggcg tagtaccagc cctgggccga gtcgcagccg
    20101 aggtcgcgca gctgctccgc ctgcacggag gtctccacgc cctccacggt gacggacagc
    20161 tggagcgtgt gggccagcga gacgatgccc tccacgatct tcaggtcgac cgggtccgcg
    20221 gggtcccgtt gcaggccctg ggtgaaggag cggtccagct tgagcgtgct ggcgggcagg
    20281 cggcgcaggt tggccaggtt ggagtagccg gtgccgaagt cgtcgagcgc gatcccgacg
    20341 ccgtactcgg ccagctcgcg caacggccgc agctcgctct cgtcggcgct gaccatggcc
    20401 gtctcggtga cttcgaggca cagcgcgctc gggtcgagcc cggactcctc aagcaccgtg
    20461 accgtgtcgt cgaccaggtc ggggtggtgc agctggcgcg gcgagaggtt gacgttcacc
    20521 ttcagcggcc tggtgccccc gatgccgcgg acctgccact ggcacgcctg ccgcacggcc
    20581 tccttgagca cccactggcc cagcggcacg atcagccccg tgtgctccgc gagcgggatg
    20641 aaccggtcgg ggcccagcac gccgtgccgc gggtggctcc agcgcaccag ggcctcggcg
    20701 ccttcgaggc tgccgtcccc catcctgacc agcggctggt actcgatgaa gaactcgcag
    20761 cccttgagcg ccgcgggcag gtggtgcgtg aggtggtggc ggctgatcgc cctggcgtcg
    20821 gagtccgggt cggccacggc gtagcggttg ccgccctccg ccttcgcgcg gtacatcgtg
    20881 atgtcggcgc tgcgcagcac ctcggccgac gtcaggtggc gtgccgggcc ctcgacgacg
    20941 ccgatgctgg cccgcaccag cagctcccgg ccgccgacct cgacgggcga ggagagcgcg
    21001 tcgagcgccc gctccgcgag gtcggtgacg gcccgccggt ccggcgggtc gatcaccagc
    21061 gcgacgaact cgtccccgcc gatgcgcgcg agcagctgcc cgggccccga ggcgcagcgc
    21121 tggaggcgct ctgcgacggc gatcagcagc tggtcgccga cggcgtggcc gaggctgtcg
    21181 ttgacggcct tgaagccgtc gaggtccagg tagcacaggc cgatcctggc cgtgccctgc
    21241 ccgccgcggt ccagtgcctg ttccagccgt tcgaagaaca gggagcggtt gggcaggtcg
    21301 gtcagcgcgt cgtgggtcgc ctggtagcgc aggcggaggg tcagcaggcg ccgctcggtg
    21361 acgtcctcca tcatggccag caggtaacgg ggtccgccgg ccgggtcgcg cagcagcgag
    21421 accgtcaggt tcgtccacag catcgtgccg tcggaacggt ggtaggactt ctcgacctgg
    21481 tagtggtccc gggtgccgcg catcagctcc tccagcatgc gccacgcctc ggggcggtcg
    21541 tccgggctcg cccactccag cacgttgcgg ctgcgcacct gctcctctgt gctgccgaac
    21601 atctggccga gcgcgtcgtt gacgtcgatg atcgtgccgt ccatgtcggc gatgccgatg
    21661 ccgagcgcgg cgcccttgaa caccgcgcgg aaccgggcct cgctctcgtg cagcgcgtcg
    21721 gtcatctccg tccgcgcggc gagcgcggcg cgcgagaccg cctcctgctc ggtcctcgtg
    21781 cgctcctgga gggcccgggc gaagccggcg gacacggcgt gctggagccg tgtgcagcgg
    21841 gcgcgcagtt cttcgggcgc cggccggtcc ggccccggcg gcggcccgca gtgcgcgacc
    21901 agccccgagt cgatcacgcc gagaacgctc gggagcgcgt cggccgggca gcgggcgtcg
    21961 acgagcgcgg cgccgacggc ccggccgggc gcggggtcga agcgcgcggc gcccagcgcg
    22021 tcggccagtc ggcgggcgag cggcagcagc accgcctcga actccggtac cggcagcgac
    22081 gtgagggcgc ggggatggac ggcgcgggcc cagagggcgg tgaaacggcg caggccggcg
    22141 gacggctcct gacccgttcc ggtgcgatgg tggccggtcg gccccggtgg cgaggatgtc
    22201 accctgtgcg tcctacttcc gcgaaaccgc cgtgggccat gggaccctcc tcgtcgggcg
    22261 gcgcgtcggg ccgcccttcg ggcaacggga ccacgcccgg ggcgtcgtga tggaaacggt
    22321 cgaagaagcg cgcggaccgc gcgcgggagc gcgagcgcgg cgtcgcgtcg ctccggcggc
    22381 gttcaccgcc ggggcggtgc ggcacggcgg ccggcggcgg ggcgacctgc cgggcggcgc
    22441 ggtcctgccg gtgggcgggc gcgccgccca ccgggccggg gagcgcgggg gccgccgtgc
    22501 ggcgggccag ggagccgccg ggcccgcccg gggggagggc acgcgtgcgg ggcgggagga
    22561 ggccggacgg accgacgccg ggcggcgccc aggcggaacg ttccatcggc gtctccaatg
    22621 tcccctgcat atgctcgatg tggcctcagg cggtcgagac tactgacccg gcggcagatc
    22681 ggggaaggaa acagcggagc aacatcgttc tgcgggacgg ttacctgtcc atctgtccgg
    22741 taatgggtgc gcgcccgacc gccgtgatca cgccacgggt ggcgcgatgt gatcggtcgt
    22801 cagagcgaga cgccgtgtcc gcgcagatag gcgaccgggt cgacgtctga accgaagccc
    22861 tctcccgtcc ggatctcgaa gtgcaggtgc gggccactgg agttgcccgt ggaaccggcg
    22921 cgccccacct gccggcccgt ggtgacggac tggccctcgg acacggagat ggccgagagg
    22981 tgcgcgtact ggctgtagtg gccgtcgggg tgccggacga tgacctcgta gccgaacgag
    23041 ccggcccagc ccgccgagac gacggtgccg gccgccaccg acttcacgga tgtgcccgtc
    23101 ggcacgggga agtcgacgcc cgtgtggtag ccgagggacc aggagccgcc cgaggatcgg
    23161 tacgcggtgc cggtgcccgc gctgaccggc gcggtgtagg cgggggccgc ctcggcgggc
    23221 tgctcctcgc gctcgccctg cggctgctcg gccggctcgg gctcgggctc gggttccggc
    23281 tcgggcgccg gctcgggttc cggtgcttcg cgcggttcct cggcggccgg ctcctcgcgc
    23341 ggctccgcgg cctcccgctc ctgctcctcc gtgccgccgt cggccggtgc gcgcagcgcg
    23401 agccgctgcc ccggcaggat gaggtccggg tcgctgccga cggtcctgcg gttgagctcg
    23461 tagagcgact gccagccgcc gcgcacgtcc ttggcgctcg cgatgccgga cagggtgtcg
    23521 ccgcggacca cctcgtacag gtcgcccgcc cgctcgccgc gcccggtcgg ggtgctcgtc
    23581 cgcgtcgcgg actcctcggc cgcgggcgcc cgttccgcgg tgggggcggg ccctggagcg
    23641 tcggcgggcg cgatgtcggg gcgcacgccg tcacgggtga ggccggcctc ggccgcgcac
    23701 gcgggccacg cccgcgggcc ctgcccgtcg aggacttctt ccgcgacggc gatctgctgg
    23761 tcacgggtgg cgaggtcggc gcgcggcgcg tacgcggtgc cgccgtagga ctcccacgtg
    23821 ctctgctgga actggagccc gccgaagaag ccgttgcccg tgttgatgtc ccaccggccg
    23881 ctgctctcgc actcggcgac ctcctcccag gtgtcgacgg gggccgccgc cgcgacgccg
    23941 gcgcccagca gcgggatggc gagccccgcg cccgaggcgg tgacggtcag cgaggcgcgg
    24001 gacaccgcac tcggtcggta acgacggtga cgtccacgtg aggtcatggg cgggtcccct
    24061 ccctggccga gtgctgggac gccccgtcgg cccacgtgcg gatcgggcgc gtcgtgcggc
    24121 ggcaccacga tatgggcgcc gggtcgcgcg cggcaaggga gccgggagtc acgtgtgacg
    24181 gcgggtcagg gatccttctg cgccggagcg cccggggcgt cgcccgtgcc cgcggacacc
    24241 cgggtgccgc ccgagccggc cgcggtcccg tcccgcgcgc cgggggcggc gccgtcccgc
    24301 tccccggcct ccggcggctg cgcgggcccg ggcgc
//
