LOCUS       NZ_CP084541            22607 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces marincola strain SCSIO 64649 chromosome, complete
            genome.
ACCESSION   NZ_CP084541
VERSION     NZ_CP084541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Strepomyces indimicinicus sp. nov., an antibiotic producing
            actinomycetes isolated from the marine environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Sciences, 164 Xingang West Road, guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. V6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 444.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020410765.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,763
            CDSs (total)                      :: 5,689
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 74
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 21 of 77
            Pseudo Genes (incomplete)         :: 60 of 77
            Pseudo Genes (internal stop)      :: 2 of 77
            Pseudo Genes (multiple problems)  :: 6 of 77
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:57:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5024347
            Orig. end                         :: 5046954
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22607
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="28"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22607
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22607
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12607](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12607)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(1962..1977)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
     misc_feature    complement(2806..2815)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    3093..3108
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            3433..5691
                     /locus_tag="LC193_RS22140"
                     /old_locus_tag="LC193_22140"
     CDS             3433..5691
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020557357.1"
                     /locus_tag="LC193_RS22140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22140"
                     /product="right-handed parallel beta-helix
                     repeat-containing protein"
                     /protein_id="WP_226076819.1"
                     /transl_table=11
                     /translation="MTDEPIRVAPRTRGAHRTIAEALAVAQAGAVISIAPGEYAETFRL
                     ARRVTLLPQAGDGSVTVALPPGVGPLTVAAPDCRMRGLVLRGADPAEALLWVEDASGLT
                     LEDCVVTHGRVEVLGSRNFVPRPEVPVGSIPLDNDLSAELADPTAGGVLVTRRTRLRAA
                     RHTALHLTGDALARLDDTAIEGVEGIGVAVSGQAVLRADQLRVHGGSGSALRARDSSRV
                     LLRGSGLFGAGRNGVLVQDTAEALLTDCRVENPARSGVRLDHTARAEINESTLAGARLS
                     GVEVRDQARVMARGARVTGGETGVRLRSSEESLIFHCTVTGQQGNGVELAAGAAPRLRG
                     VRVARSGKHGVFVGEGAQGTFDHCDVIASALPALHVARDAAPRFRGCRVFDSAHDLGVE
                     AGAQAVFENCVAINVGSPRLPGMDRGSGPEQPPTRGPGHDPRRKAPGPEQDRERGRGPA
                     AAAPTPKASADPGARSSEDEYEEGPTQESLPELLAELDELVGLDGVKRDVGGLVKLMQT
                     VRMRQEAGLPAPPLSRHLVFAGNPGTGKTTVARLYGRLLSALGLLSRGHLVEVDRSALV
                     GEYIGHTGPKTTEAFQQAMGGVLFIDEAYALTPPGVAQDFGSEAIATLVKLMEDHRDEV
                     VVIAAGYPGDMNRFIASNPGLASRFTRSLTFADYSTDELVRIVEHNARKHRYQLTDNAR
                     KALGGYIGAIPRGEGFGNGRTARQLFQQMTERQAMRVAELTDPEADALMSLTEEDLPG"
     misc_feature    5791..5806
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.87"
                     /tool="antismash"
     misc_feature    5795..5810
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     gene            5907..7088
                     /locus_tag="LC193_RS22145"
                     /old_locus_tag="LC193_22145"
     CDS             5907..7088
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018836777.1"
                     /locus_tag="LC193_RS22145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22145"
                     /product="S1 family peptidase"
                     /protein_id="WP_226076822.1"
                     /transl_table=11
                     /translation="MRRATALRLRVCTSALLVLGVLGATEASADPAPDSAPDATREAAA
                     AAPALVDALARDLGIGEDEARTRLAQEAEAAEAQPAARDAAGDAFAGAWFDPAAGSLVV
                     AVTDPAAAGEVRETGAETRLVAHSAAELDATAEAIADLAEGGAPPEGVVGWGVDTRANT
                     VTLDIVRGTAGDAEVAAFVADARRAGPVEVRERADAAPAPFAAGVVGGDPYRTGNVRCS
                     IGFSVHGGFVTAGHCGQPGAAVYGWDGSLMGRFEGSSWPGNDYGWVSVGHGWWTVPVVL
                     GWGTVSDALVRGSAEAPIGASVCRSGSTTGWHCGTVLGKNETVNYVGGEVVHGLTRTSV
                     CAQPGDSGGSYISGDQAQGVTSGGWGNCSSGGQTWHQPVNEILSAYGLRLHTA"
     misc_feature    complement(5953..5968)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            7198..7899
                     /locus_tag="LC193_RS22150"
                     /old_locus_tag="LC193_22150"
     CDS             7198..7899
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019885417.1"
                     /locus_tag="LC193_RS22150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22150"
                     /product="SIMPL domain-containing protein"
                     /protein_id="WP_226076824.1"
                     /transl_table=11
                     /translation="MTDNAPAPVPATPEAPRVSVRGSARLEVEPEIARLGVAVSARGAD
                     RAAALAALTRRNADALDLIKSYGDAIESMSTGSFVITPELTRRGRGEQVRAHHGRVHLS
                     VTVADFGVLGELTTRLADLDLTRVDGPWWALRPTSPVHREARVQAVREAVTRAREYAAA
                     LGSDLAALVELADVGADIEAPVAYGRGARAAAPAAAGAAEAPPPALDLEPRRQTVRAQV
                     NARFTIVPPVL"
     gene            complement(7986..9863)
                     /locus_tag="LC193_RS22155"
                     /old_locus_tag="LC193_22155"
     CDS             complement(7986..9863)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639734.1"
                     /locus_tag="LC193_RS22155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22155"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_226076826.1"
                     /transl_table=11
                     /translation="MTSSNNPPPPDVHHQRTLAMTGRAVTTELPTILGQATRLAWRTDR
                     PAVVAVALGQSVAAVAAATALIATTAVLEHLLADRPWRDSADAALPVITMLLIALVVRY
                     TADGAARMAAARVGPRVVTEASYAVVASANRMEFTGYEQPGVRDALEAADDGAQSMADL
                     VTDAQAAVASLAQTIGALSVLVTLHPVLLPLIAMTALPGAAATLRVARIEHTVRHDTMS
                     DRRLRRYLYFHTTDRDSAAEIRAARMAPFLQGRFRAVSRRLDAAVLAGARRAERARVAG
                     DLGAALGQLVTWAALAALAATGRIDLAAAGAAVIAVRTITAALTGLGDSAGRLFRSALY
                     VGDWDRWNVLAAEHAARRGTVPIPARGPDVIEVDDVSYAYPGTERRALNGVSLSVRRGE
                     VVALVGENGAGKSTLVQLLTGLALPDSGAVRWDGVDLADADPDTVWAHVALVPQQYTRW
                     PLTARENIQLGTPRPEGDQAVHNAAATARADSVIAALPQRLDTSLARSWAGGHDLSGGQ
                     WQRIALARAFHRDAALLVLDEPTAALDSRAESALFRTMRDLAADRATVLVTHRLISTRH
                     ADRIVVMHQGRIAEQGTFAELSAMPGSVFAELLALQEGRQSAVPTLTAT"
     gene            complement(10001..10420)
                     /locus_tag="LC193_RS22160"
                     /old_locus_tag="LC193_22160"
     CDS             complement(10001..10420)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="LC193_RS22160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22160"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_226076828.1"
                     /sec_met_domain="PF13471 (E-value: 3.8e-13, bitscore: 47.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSIESYRTVRAGTPRQRAVAWLGLAAAVLLLRLPFRWTVRAART
                     ARFIGRRPLPAERAQVMVEAVRHAGRGWPVRVACLESSLGAVLACALCGRRLAWCVGAR
                     VAPPVEYHAWARIPGDEPVGEYVGDGWHYLPALEI"
     gene            complement(10417..10698)
                     /locus_tag="LC193_RS22165"
                     /old_locus_tag="LC193_22165"
     CDS             complement(10417..10698)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="LC193_RS22165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22165"
                     /product="PqqD family peptide modification chaperone"
                     /protein_id="WP_226076830.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.1e-11,
                     bitscore: 42.1, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.4e-07, bitscore: 30.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLRDGVHAILTDTAGALLDERSGRWTHLSGTAAVALRLLLSTEE
                     RRQAIEEFAGRFAVPREQAEQDLLAVERGLTDRGLLAAPRRRGRRWWR"
     aSDomain        complement(10453..10698)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_LC193_RS22165_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.00E-13"
                     /identifier="RREFam002.1"
                     /label="LC193_RS22165"
                     /locus_tag="LC193_RS22165"
                     /protein_end="82"
                     /protein_start="0"
                     /score="42.1"
                     /tool="antismash"
                     /translation="MRLRDGVHAILTDTAGALLDERSGRWTHLSGTAAVALRLLLSTEE
                     RRQAIEEFAGRFAVPREQAEQDLLAVERGLTDRGLLA"
     gene            complement(10685..12607)
                     /locus_tag="LC193_RS22170"
                     /old_locus_tag="LC193_22170"
     CDS             complement(10685..12607)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033561.1"
                     /locus_tag="LC193_RS22170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22170"
                     /product="albusnodin/ikarugamycin family macrolactam
                     cyclase"
                     /protein_id="WP_318842180.1"
                     /sec_met_domain="Asn_synthase (E-value: 2e-18, bitscore:
                     65.6, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRAPVPRVRCRRPPVPPTERVRGVAVQWCAGWHGQKPPARAPVN
                     SQEVPGCPGTWTCGWPAARVRTTGTAGVGLTVIGMCGARPGDLESGLADVRAGRWRALT
                     RWPGSYLAIATRGQVTAVIGDLAGQHSVYWRPFDAGVWWATAAMPLAGLDGARVDRIAL
                     AARLALGQPDISGSRSLFHRVSRVATGHLLLLEPGGAHSVPFEPSRPRPVSMAEGASAV
                     AGALSDAVSVRLDGRPVVADLAGLDSTTLVCLAAAQDVPVTALTHADPRMRDDDLAYAR
                     RTAAVVPGVRHHVFAGSADAVMYAGLQGPRSVPQTDEPTLYSATARIKRAQLELVAADH
                     GGSVYFTGEGGDVVLSASAGYLADLYRAGRRREAWRHTVAHARVRRMSPLALWQRVGPL
                     ARGGVAGGWRRAAEELRAAQPSVVVATPEAAARQVLSPCARWMSSEVRELLADRVDTVA
                     DTLGEEPGMSVWSDRQDLARIGGSLAGWHAITRSQGLTLAAPYLDNEVVRTCLSIDAAE
                     RGAADRYKPLLAAAFPTGPVPGFVLGRTTKGGLDGVAHAGLRRHARVISELLGPNSRLA
                     DLGLLPRSGVLDDVASAAGGRLTGAGAIHYAVAAELWLRQVESVSAWWSSVRHSPGEAQ
                     SHAAA"
     misc_feature    complement(11432..11434)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12628..12786)
                     /locus_tag="LC193_RS22175"
                     /old_locus_tag="LC193_22175"
     CDS             complement(12628..12786)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS22175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_22175"
                     /product="hypothetical protein"
                     /protein_id="WP_226076834.1"
                     /transl_table=11
                     /translation="MSTEPTTPTQAAYQPPTLSDGGPVADVTLGKNGFDVQDNTEYRQK
                     TPGVSAL"
     gene            13038..14378
                     /locus_tag="LC193_RS22180"
                     /old_locus_tag="LC193_22180"
     CDS             13038..14378
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015449438.1"
                     /locus_tag="LC193_RS22180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22180"
                     /product="M48 family metallopeptidase"
                     /protein_id="WP_226076836.1"
                     /transl_table=11
                     /translation="MHLDEHPLVYLLRVHGWSATDYLTRLSAVHVKLGYGPIAKDRKRI
                     TRWTRYNVTPDMPAQRAMAHLHRIPEDEITARPWPEWLKLACIRERQLLSAAWTPDTTL
                     HLLDRVAIGGPMDRRGFLLVTGITPVLAGAVTAQPATAHATGRRIGAAAPELFEQSLAV
                     LRRQDDQFGSGQVHTSARAQLRLITASLQNASYTEATGRRLHGAAAEAARICAWTAYDS
                     GRHALAEEFYLAALRAAATAADPVVTANTLAFWAIQRYSTGDPRGAADLIAHALTLTGR
                     IGSARMEAMLHARLARAHAKAGDEHASLHSQGHALAAYDRARDQSPNEDPDCVYWVSLG
                     ELRMLHGSCALNLGRPRRALAEFETAAGEYREDDFPRAAVIYLARGAEARIALEDLDGA
                     VDIAQRAVDHMGGVTSARGTSTLDDVRRQFHAHRTVPVVSEFLARTA"
     misc_feature    13356..13358
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14745..14942
                     /locus_tag="LC193_RS22185"
                     /old_locus_tag="LC193_22185"
     CDS             14745..14942
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435474.1"
                     /locus_tag="LC193_RS22185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22185"
                     /product="hypothetical protein"
                     /protein_id="WP_226076838.1"
                     /transl_table=11
                     /translation="MMPVQVSTRISPVQAGSAERSALTSLISEPEAPVSGAPVYSPEAA
                     GFLLLLILLSPKQPSEPRDK"
     gene            15027..15731
                     /locus_tag="LC193_RS22190"
                     /old_locus_tag="LC193_22190"
     CDS             15027..15731
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS22190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_22190"
                     /product="hypothetical protein"
                     /protein_id="WP_226076840.1"
                     /transl_table=11
                     /translation="MSFPDPSPRAVYAAEVESLAGRVRDALAGAPAPAGPARHVEEAED
                     PKAALAAVRVLGPDVFAPALLVGAPFGPADCEAVTEAFRVFPPGPDDTAEAVWRDHATA
                     ALLTRHGGDPVASGGPPVARPLERWRPWTSWLAGLSPLALPGVNGPLPRPDLRAAQALA
                     MGTTRALLRRDHPTAARLARWAAFAHGHGASPPLDLLAVLDHVDLHGGTARTALDTAVA
                     RRLAAGAERRTA"
     gene            15728..16684
                     /locus_tag="LC193_RS22195"
                     /old_locus_tag="LC193_22195"
     CDS             15728..16684
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643546.1"
                     /locus_tag="LC193_RS22195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22195"
                     /product="DUF6895 family protein"
                     /protein_id="WP_226076841.1"
                     /transl_table=11
                     /translation="MTAPSPQSPPPSSPAAVRRTAHALSTGAIGWLHANRERGAFAPDV
                     TGELTDPDSVYKPLGESVLAASLVLREGIASPTDRRAAESLMEFAWAQLREGDLLYERQ
                     LRYMMMTDPLELYTHFARAGFRHDRLHALFNHLGGLTSRGAAEQLPNRRLAVANASRVA
                     GLDRQADWSVLTDATWLGQTPEPWAIDWMTAYCVTHTVFHVTDWGGRPDALSPRIQDYL
                     GRWLPVWIDIWQEIQEWDLVAELLIVDACLPEPRSAPEVWERLAAVQRPDGLVPRNGEP
                     VTEDPDEAFREHQHTTVVAAVAGTLALSRHRGARALV"
     gene            16690..17709
                     /locus_tag="LC193_RS22200"
                     /old_locus_tag="LC193_22200"
     CDS             16690..17709
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643547.1"
                     /locus_tag="LC193_RS22200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22200"
                     /product="serine hydrolase"
                     /protein_id="WP_226076842.1"
                     /transl_table=11
                     /translation="MSGLDRRLSAVADAAGPPAGIAVAVRAPGGDATLCRGTTDRRGGA
                     PVTERTRFEVGSVSKTFTALLLAEMAERGDVALDDPAGTRGHRVTLEHLATHTSGLPRL
                     PPGLLRTAWRSWYTNPYGHYPPERLLPALARTRVRREPGTRVHYSNFGVGLLGRLLAEE
                     AGTDYGTLLTARVLDPLGLRDTTADRSLPQAVGHRHGRPLPPWDIPALPGAGAVRSSAA
                     DLLRYLAALTGPDAAVPGGGPLRAALREVVRPRVTGPGGPALPLAWSTRERPGHVLYHH
                     SGGTRGSTAFAGFCPEHGVHVVALAATGPTVRGRFIQSAYLLLRSLAAEAAERTGERG"
     gene            complement(17787..18413)
                     /locus_tag="LC193_RS22205"
                     /old_locus_tag="LC193_22205"
     CDS             complement(17787..18413)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS22205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_22205"
                     /product="hypothetical protein"
                     /protein_id="WP_226076843.1"
                     /transl_table=11
                     /translation="MGADSAMKDFAPGFIATKWAPGSLGGWYSDPPQAVRWAGDLVVVG
                     EVVRWTSPERENEGNGAFVHRVPDGTYPVYVNDGVPSGWEDEDPERYRVDTLFIPLAGP
                     ERLRTTRWSHGYDDVGQYLDGYACLRSEGARRGDEDGAIRRAKRALLSEDARTGASHGI
                     NEVVDPETGANMLSFPVCRYGEVHGFEALGEGDETLALLFLANHD"
     gene            18622..19452
                     /locus_tag="LC193_RS22210"
                     /old_locus_tag="LC193_22210"
     CDS             18622..19452
                     /GO_function="GO:0003906 - DNA-(apurinic or apyrimidinic
                     site) endonuclease activity [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0019104 - DNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006284 - base-excision repair [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520761.1"
                     /locus_tag="LC193_RS22210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22210"
                     /product="DNA-formamidopyrimidine glycosylase family
                     protein"
                     /protein_id="WP_226076844.1"
                     /transl_table=11
                     /translation="MPEGDTVAQAARRLREALAGHRLVRADLRVPRLATADLRGRLVLD
                     VVPRGKHLLTRVEGGLTLHSHLRMDGSWRVFPAGRRWTGGPAHQIRAVLDTGARVAVGY
                     RLPVLDLLRTADEPRVVGHLGPDLLGADWDADEALRRLLADPAREVGPALLDQRNLAGV
                     GNVFMAELCFIAGVTPWTPVGEVAAPDRLVAEARRLLVANRDRPDRTTTTRTHPRERGV
                     RGSPGPRLYVYGRAGRPCLLCGATVRTATESRDRAGQERPAFWCPRCQRGPAPA"
     misc_feature    complement(19485..19500)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.87"
                     /tool="antismash"
     gene            19581..19844
                     /locus_tag="LC193_RS22215"
                     /old_locus_tag="LC193_22215"
     CDS             19581..19844
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569422.1"
                     /locus_tag="LC193_RS22215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22215"
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="WP_226078849.1"
                     /transl_table=11
                     /translation="MEISGIISAIVIGLVIGALARLVLPGRQRIGVLWTIAVGIIAALI
                     GTALAAALGVADTDGVDWLELLLQLALAALGVTLLDRVKSRA"
     misc_feature    19913..19922
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            20176..20556
                     /locus_tag="LC193_RS22220"
                     /old_locus_tag="LC193_22220"
     CDS             20176..20556
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS22220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_22220"
                     /product="hypothetical protein"
                     /protein_id="WP_226076845.1"
                     /transl_table=11
                     /translation="MVDINPHVDPPPEHGRLRVARDTLAAIAELLEGPALALAQAEGPA
                     LGVRRLVERMDDFSGEWEHGVAQLGECAEAAVRALDMVLWSLPAPPEPARGDARDGGPG
                     GAAGRGACDTCDACGSDGVIAA"
     gene            20553..21143
                     /locus_tag="LC193_RS22225"
                     /old_locus_tag="LC193_22225"
     CDS             20553..21143
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS22225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_22225"
                     /product="hypothetical protein"
                     /protein_id="WP_226076846.1"
                     /transl_table=11
                     /translation="MSVVNGPGAPRGSHPRPLPPGGGQGPGQEADYPALGFVPCPGDQP
                     VAAQIARNVREAAATLGTVLGLLDSVVPPGEWRGRPAAALKGFERGFRPKVAAAREAFA
                     AVADVLEDWADHMREAQQDARALEAEARAARERPGLDAVRARARALAADYDTYGAFVAE
                     RLGEAGDAAPDKPGWLTGLARDIDGLTTMRPAP"
     gene            complement(21165..21596)
                     /locus_tag="LC193_RS22230"
                     /old_locus_tag="LC193_22230"
     CDS             complement(21165..21596)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972358.1"
                     /locus_tag="LC193_RS22230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22230"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_226076848.1"
                     /transl_table=11
                     /translation="MTRSSLEAAVVMSHELFMRTSDRVESVLAEHGLTHATAQALWAID
                     PAEAPPSMKELAGRLHCNAPNLSFVMNQLGGRGLVERSADPADRRSRVVTLTADGRRVR
                     SAVIEATLALSPLARLDADDLLTLVGLLGKVLEPAPRPA"
     gene            21917..22321
                     /locus_tag="LC193_RS22235"
                     /old_locus_tag="LC193_22235"
     CDS             21917..22321
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF019013.5"
                     /locus_tag="LC193_RS22235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_22235"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_226076850.1"
                     /sec_met_domain="PF07366 (E-value: 3e-08, bitscore: 31.9,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVEQNKEIARRLVQGFSVDGDIDETFALLHEDAVWTVMAHPASF
                     GASGDMSKAQFVEHMKGFRAVTPNGLRMTVTGVTAEGDRVAVEAESSGTLGNGKTFGQV
                     YHFLFEIRDGKVMVAREYLDTARGAAVFGS"
ORIGIN
        1 ggcggacggc ggcgccccga cgaacctgcg cgtcgtcgag ctgtcggacg gcgtcaactc
       61 ccgtttcgtc gacgtcaccc gcgcggacgc cccgcgcctg ctcgacggcg agatgagccg
      121 gatggacggc gtcgccgtca cgcgcctggc gaacgatgcc gggttcgagg tccgcccgca
      181 gggcggcgtc cgcgcgaacg agtggcagac gtacagcacc agcgggaaga tcaccgggca
      241 gcgcatcgac gtctacgtgg gcggccgggt cgtcgacggc cagtccttca ggatcaccta
      301 cccggagcag ggcacgccca cctggaccag gggggccgaa ggcgccgggg ggcaccgctc
      361 gtggcacgac ttcggcgagg tcgacatcaa gggcatgaag aacggccacg tggcgctgat
      421 ctcccacacg ggcgatgtgg tcttcgaccg ccgggtcctg cccagcggca ggatcgtcga
      481 cagccacgcc gccaaccccg gcctgaccgg cggcgggatc tcctacgggc gaggcagccg
      541 cgagcactgg tccgagatca ggacggacgg caccctcggc gacttcggcc gccgcaagtg
      601 gagcgtcagc gggcgcgcct gggtggacta cagccagaac ggcaaccccg tccggcactt
      661 ccgcgaggtt ccgcagggcg ggcacatcct ggccgacatg cggggcgtcc ccgcccactc
      721 gtggcacggc cgcaccagcg tctggcaccg gtacgacgcc gagtacacgc aggtcgccac
      781 cggcgacagg acgtggggcc tcggccgcgc gtggaccgac aacatgctgg acccggccac
      841 cggccagatg aagctggtgc accagaagat cagccgggtc gccggctggg gcaacctcga
      901 caacctccgc cgtttccacg cgcacgacat caacccgaac ggcagctgga gcagccactg
      961 gaagggcgta tcgccgcacg gcaaggaggt cggcggctcc gcgcccatga agaacggcga
     1021 cacgctgaac acccagcgga tcgccgagca gcggcccccg cactggtacc ggacgtggct
     1081 cagctccgag gtgcggcaca cggacttcgg ccccggctgg ttcggccggc acttcggcgg
     1141 cgctccgcgt ctcgacgccg acggcgtgcc ggtcgtgcag gcgccctggg cgcgcgacaa
     1201 cacgttgcag gtcggccgct gggagcaggt gcgcggcggc gagacgatcg accacggcgt
     1261 gtcgttcacc agccagcagg agtacctgaa gatccggatg agccacaccg gggcggtcac
     1321 ggacgagacc cgcaagctca tgaacggcaa cgaactgcgc gtgggcgacg tcgagatgcc
     1381 cgagggcgtc acgttgccca accactacca ggcgtggtcg gagggcgcgg acaacctgaa
     1441 gggccaccgc tcctacaacc cggcggactt caacaacatc aacctgccgg cccagagcgg
     1501 gctgcgcggc caggacgtgc tgttcgtcga ccgcttccac gtcaacccga acgccgccga
     1561 cgcgttcacg ccgaccgcca acgccgccga ctggaacatc accagggtcg gcttcaagga
     1621 cggcaccatg ctggagtacc gcccgcgccc gcaggccggc gtggacaacg cgctcgacgt
     1681 ccggcggacg gcccaccagg gcggcaacgc ggactggacg catctcgacc accacggcgc
     1741 ggtgatcgcc aggcaggaca cgttcggact gggcgccgac ggcttccagg tctgggccaa
     1801 gggcagcgac aacccgttca gcaactcctt caagtgggag gacagcaacg gcaacaccgg
     1861 catccgcaag gtctcggccg ccaacggcat ccactaccgg ggctgggacc gccactcctt
     1921 ccaggacttc cagggcggcc gactggtgca cgagcaccgg ctgttcgccg acggcgccac
     1981 cgttcagtcc tggaagctgc cgggcgccgc aggcgacgtg ggggagaact ggcgctggaa
     2041 caagatggac gcgaacggcg tggccaagga gttcggcaac cagggcgacc gggtgcgcgt
     2101 gtggtacaag ggcaacacgg agttcgactc gtggcagccg ggcgcccgct gggtcgactt
     2161 catgggcacg ggcgacgacg ccgtgcgcat ccaggagatc ccgaacttcg ccaagagcgg
     2221 caacccggtg cgcgacatgc tcaccaccaa cccgttccgc gtccgcgagt acgccgccac
     2281 gcccgacgac ctcggcgcgg tgcggggcgc cgacgcctac cgcgcgtgga aggagcacga
     2341 cgccggcatc gtgacgcgcg agatgaagcg gctgcccgac ggcacgttcc tggagaagga
     2401 cacctggcag aagcagtggc gccggtacgc cttcggcgcg gacggcacgc accacgtgat
     2461 caacgagcgc accatccacg gcaacgtctt cgagtacgac accttcgggc gggccacgct
     2521 cgtcggccgg gagacccact tcatcgactt ctccaacgag ttccgcgggt acaccaggga
     2581 atggcgcgaa ccgctgcgct ggagctgggg cccggccgtc accaacgcgc ccggcggggt
     2641 ccggggcgcc gagtccctgt acacgccgtt cctgttcaac tcgacggggg cgctgctggt
     2701 cgagggcgcc caggagttcg tgctcgactt cgtgatgaac ctcgcggtgt tcggcatcgt
     2761 ctcggcggcc accggcaccc cgttcaccat caccgacgtc cagcaggccg ccttcgcggc
     2821 ggccctcggc accggcgtca agaccctctc cggcggcctg cacaactggg cggcccaccg
     2881 cttcggctgg aagtccggct ggggcaacca cgaccagggc ctgccgtacc actaccggca
     2941 gaacaacgac gacgtcgcgg gcgagttcgc gggcaacgag aaggtgctgc gctggcgcgc
     3001 cggcacctac gacttcttca aggacacgtc cgtcggcgcc ctgaccggct tcgccgcggg
     3061 ggcggcgggc gcggcgatct tcggcgtcaa ggactccgag ggcgaacggc acctgctctc
     3121 gggcggcgac gcggcgctgt tcggcgcggc cggcgcgctc ggcggcgtca tcggcgggct
     3181 cagcgtcgcc gccgtgcgcg gcatgatcca gaacacggcg gccagccggt tctaccaccg
     3241 cgccggtgtg atcgacttcc tcgtgatgcc gatcatcggc aagctgatgg acaagaccct
     3301 ggcctacctc gtgttcgggc cgatcatccg gccggcgctc ggcatcaccc cgcccgagcc
     3361 cgcgccccag cccaccccga cccccgtgcc cacgcccgcg ccggggacca acccatagga
     3421 ggagtcgggt ccatgaccga cgagccgatc cgtgtcgcgc ccaggaccag gggcgcccac
     3481 cggaccatcg ccgaggccct ggcggtcgcc caggccggcg cggtgatcag catcgcgccc
     3541 ggcgagtacg cggagacgtt ccggctggcc cgccgcgtga cgctgctgcc gcaggcgggc
     3601 gacggctcgg tgaccgtcgc cctgccgccg ggcgtggggc ccctgacggt ggccgcgccc
     3661 gactgccgga tgcgcggcct ggtgctgcgc ggcgccgacc cggccgaggc cctgctgtgg
     3721 gtcgaggacg cctcgggcct gacgcttgag gactgcgtcg tcacccacgg ccgggtcgag
     3781 gtgctcgggt cgcggaactt cgttccccgg cccgaagtgc cggtcggcag catcccgttg
     3841 gacaacgacc tgtcggccga gctggccgac ccgacggcgg gcggcgtcct ggtgacccgc
     3901 cgcacccggc tgcgggccgc gcggcacacc gcgctgcacc tcacgggcga cgccctggcc
     3961 cgcctggacg acaccgcgat cgagggcgtg gagggcatcg gcgtggccgt ctcgggccag
     4021 gccgtgctgc gggccgacca gttgcgcgtg cacggcggtt cgggctcggc gctgcgcgcc
     4081 cgcgactcct cgcgcgtgct gctgcgcggc agcggcctgt tcggcgcggg ccgcaacggg
     4141 gtgctggtgc aggacacggc cgaggcgctg ctcaccgact gccgggtgga gaacccggcg
     4201 cgctccgggg tcaggctcga ccacacggcg cgcgccgaga tcaacgagtc cacgctcgcg
     4261 ggcgccaggc tgtcgggcgt cgaagtgcgc gaccaggcgc gggtgatggc gcgtggggcg
     4321 cgcgtgacgg gcggcgagac gggcgtgcgg ctgcgctcca gcgaggagtc gctgatcttc
     4381 cactgcaccg tgacggggca gcagggcaac ggcgtcgagc tggccgcggg cgcggcgccc
     4441 cggctgcgcg gggtgcgggt ggcgcgttcc ggcaagcacg gcgtgttcgt gggcgagggc
     4501 gcccagggca cgttcgacca ctgcgacgtg atcgcgagcg ccctgcccgc gctgcacgtg
     4561 gcgcgggacg cggcgccgcg cttccgcggc tgccgggtct tcgactcggc gcacgacctg
     4621 ggcgtggagg cgggcgcgca ggcggtgttc gagaactgcg tcgcgatcaa cgtcggctcg
     4681 ccccggctgc cgggcatgga ccgcggcagc ggtcccgagc agccgccgac gcgcggcccc
     4741 ggccacgacc cgcggcgcaa ggcgccgggg ccggaacagg accgggagcg gggccggggg
     4801 cccgccgccg cggcccccac gccgaaggcg tcggccgacc cgggcgcccg gtcgtccgag
     4861 gacgagtacg aggaggggcc cacgcaggag tcgctgccgg aactgctcgc ggagctggac
     4921 gagttggtgg gtcttgacgg cgtcaagcgg gacgtcggcg ggctggtcaa gctgatgcag
     4981 accgtcagga tgcggcagga ggcgggcctg ccggccccgc cgctcagccg ccacctggtc
     5041 ttcgcgggga accccggcac gggcaagacc acggtcgccc ggctctacgg ccggctgctg
     5101 agcgcgctcg ggctgctctc gcgcggccac ctggtcgagg tggaccgcag cgccctggtg
     5161 ggtgagtaca tcggccacac gggaccgaag accaccgagg cgttccagca ggccatgggc
     5221 ggcgtgctgt tcatcgacga ggcgtacgcg ctcaccccgc ccggggtggc gcaggacttc
     5281 ggcagcgagg ccatcgcgac cctggtgaag ctgatggagg accaccgcga cgaggtcgtc
     5341 gtcatcgcgg ccggctaccc gggggacatg aaccggttca tcgcctcgaa cccgggcctc
     5401 gcctcccgct tcacccgcag cctgacgttc gcggactact cgaccgacga gctggtccgc
     5461 atcgtcgagc acaacgcgcg caagcaccgc taccagttga ccgacaacgc gcggaaggcg
     5521 ctgggcggtt acatcggcgc gatcccgcgc ggcgagggct tcggcaacgg ccgcaccgcg
     5581 cgccagctgt tccagcagat gaccgagcgc caggcgatgc gcgtcgcgga actcaccgac
     5641 cccgaggcgg acgcgctgat gtcgctcacc gaggaggact tgccggggta ggggcgttcc
     5701 gaatgcggcg cgttccgggc gcatgcgggc ccgcccgggc ccggtcgtgc ccgcgccggg
     5761 cggtggtggg tcccggcgcg gcggcaggcc cttggtctag acatgtacat gtcgattctc
     5821 tacgctgcgt ccagtcgaca cgagcgcgct tccgtctgct ccgttccgcc cccaggcagg
     5881 tagaacgacc gaaggagacc cccaccatga gacgcgccac ggccctgcgc ctgcgtgtgt
     5941 gcacctccgc cctgctcgtc ctcggcgtcc tcggcgccac cgaggccagc gccgaccccg
     6001 cccccgattc cgcccccgac gcgacgcggg aggcggcagc cgccgcgccc gccctcgtcg
     6061 acgcactcgc ccgcgacctc ggcatcggcg aggacgaggc ccgcacccgg ctcgcccagg
     6121 aggccgaggc cgccgaggcg cagccggccg cgcgcgacgc ggcgggcgac gcgttcgccg
     6181 gcgcctggtt cgacccggcc gccggctccc tcgtcgtcgc cgtcaccgac ccggccgccg
     6241 cgggcgaggt ccgcgaaacc ggcgccgaga cccggctggt ggcgcacagc gccgccgaac
     6301 tcgacgccac cgccgaggcg atagccgacc tggccgaggg cggcgcgccg cccgagggcg
     6361 tcgtcggctg gggcgtggac acgcgcgcca acaccgtcac cctcgacatc gtccgcggca
     6421 ccgcgggcga cgcggaggtg gccgcgttcg tcgcggacgc gcgccgcgcc gggccggtcg
     6481 aggtccgcga gcgggccgac gcggcgcccg cgccgttcgc cgccggggtc gtcggcggcg
     6541 acccctaccg gacgggcaac gtccgctgct cgatcggctt ctccgtgcac ggcggcttcg
     6601 tcacggcggg gcactgcggg cagccgggcg cggccgtcta cggctgggac ggctccctga
     6661 tggggcggtt cgagggctcc tcctggcccg gcaacgacta cggctgggtg agcgtcggcc
     6721 acggctggtg gacggtcccc gtcgtgctcg gctggggcac ggtctccgac gccctcgtgc
     6781 gcggctcggc cgaggccccc atcggcgcct ccgtgtgccg ctcgggctcc accaccggct
     6841 ggcactgcgg caccgtgctc ggcaagaacg agacggtgaa ctacgtgggc ggcgaggtcg
     6901 tgcacggact gacgcgcacc agcgtgtgcg cccagcccgg tgactccggc ggctcgtaca
     6961 tcagcggcga ccaggcccag ggcgtgacct cgggcggctg gggcaactgc tcgtccggcg
     7021 gccagacctg gcaccagccg gtgaacgaga tcctgtcggc ctacgggctg cgcctgcaca
     7081 ccgcgtaacc cccggggggc cgggcccgcc gcgcggcccc ggcccccggt cccgcggggg
     7141 ccgcgccgcc gcgcggtccc cgcgaggact gtcacagggg tctgccaggg tgggggaatg
     7201 accgacaacg cccccgcccc cgtccccgcg accccggagg cgccgcgcgt ctccgtacgc
     7261 ggctcggccc gccttgaggt cgagcccgag atagcccgcc tcggcgtcgc cgtctccgcg
     7321 cgcggcgccg accgggccgc cgcgctcgcg gccctcaccc ggcgcaacgc cgacgccctc
     7381 gacctgatca agtcctacgg cgacgcgatc gagagcatga gcaccggcag cttcgtgatc
     7441 accccggagc tgaccaggcg cgggcgcggc gagcaggtgc gcgcccacca cgggcgcgtc
     7501 catctctccg tgaccgtggc cgacttcggc gtgctcggcg agctgaccac gcggctcgcc
     7561 gacctcgacc tgacccgcgt cgacggcccg tggtgggcgc tgcgcccgac ctcgcccgtg
     7621 caccgcgagg cccgcgtcca ggccgtgcgc gaggccgtga cgcgcgcccg cgagtacgcc
     7681 gccgcgctcg gctccgacct cgccgccctc gtcgaactgg ccgatgtcgg ggccgacatc
     7741 gaggcgccgg tcgcctacgg ccgcggcgcg cgggccgccg cccccgccgc ggcgggggcc
     7801 gccgaggcgc cgccgcccgc gctcgacctg gagccgcgcc gccagaccgt acgggcccag
     7861 gtcaacgccc gcttcaccat cgtcccgccc gtcctctgac ccgtcaccct tcaccgcgcc
     7921 ggacgcgccg ggggctcgcc gggccgcgaa tgagccatga gccggcctgg agtcccatcc
     7981 ggccgctacg tcgcggtcag ggtcggaacg gcggactgcc ggccttcctg gagggcgagc
     8041 agctcggcga acaccgagcc gggcatggcg gacagctcgg cgaacgtgcc ctgctcggcg
     8101 atgcggccct ggtgcatgac aacgatgcgg tcggcatggc gggtgctgat caggcggtgg
     8161 gtcaccagta cggtggcgcg gtcggctgcc aggtctcgca tcgtgcggaa cagggcggat
     8221 tcggcgcggg aatcgagagc ggctgtcggt tcgtccagga ccagcagggc ggcgtcccgg
     8281 tggaaggcgc gggccagggc gatgcgctgc cattgcccgc ccgagagatc gtggccgccc
     8341 gcccaggagc gggcgagtga ggtgtccagt cgctggggca gggcggcgat gacgctgtcg
     8401 gcccgcgcgg tggccgcggc gttgtgcacc gcctggtcgc cctcggggcg tggtgtgccg
     8461 agctgaatgt tctcccgggc ggtgagcggc cagcgggtgt actgctgtgg aaccagggcg
     8521 acatgggccc acaccgtgtc cgggtcggcg tcggccaggt cgacgccgtc ccaccgcacc
     8581 gcgccggagt ccggcagcgc gagcccggtg aggagctgca cgagcgtgga tttgccggct
     8641 ccgttctctc cgaccagggc gacgacttca cctcggcgca cgctcaggga gacaccgttg
     8701 agcgcccgcc gctcggtgcc cggataggcg tagctgacgt catccacctc gatgacatcg
     8761 ggcccccggg cagggatggg gacggtgccg cgacgggcag cgtgctcggc ggccagaacg
     8821 ttccaccggt cccagtcccc gacatacagg gcactgcgga acagccgccc cgcgctgtcg
     8881 ccaagaccgg tgagcgcggc ggtgatcgta cgcaccgcga tcaccgccgc cccggccgcg
     8941 gcgaggtcga tgcggccggt ggcagccaac gcggcgagcg cggcccaggt gaccaactgc
     9001 ccgagggcgg cgccgaggtc ccctgcgacc cgagcgcgct ccgcccggcg ggcgccggcg
     9061 agcaccgcgg cgtccaagcg gcgggagacc gcacggaagc ggccctgaag gaaaggagcc
     9121 atgcgggcgg cgcggatctc ggcggcgctg tcgcggtcgg tcgtgtggaa gtagaggtag
     9181 cgccgaaggc gtcggtccga catggtgtcg tgccgcacgg tgtgctcgat ccgggcgaca
     9241 cgcagagttg ctgccgcgcc cggcagggcg gtcatggcga tcagcggcag caggacgggg
     9301 tgcagcgtca ccaggaccga caacgcgccg atcgtctgcg cgagggacgc gacggcggct
     9361 tgggcgtccg tcacgaggtc ggccatcgat tgggcgccgt cgtccgccgc ctccaacgcg
     9421 tcgcgaacgc ccggctgttc gtagccggtg aactccatcc ggttggcgct ggcgacgacg
     9481 gcatagctcg cctcggtgac gacgcgcggg ccgacccgcg ccgccgccat gcgcgcggcg
     9541 ccgtcggcgg tgtagcgcac caccagcgcg atcagcagca tcgtgatcac gggcaacgcc
     9601 gcgtccgcgg agtcgcgcca cggccggtcg gccagcagat gctccaggac ggcggtggtg
     9661 gcgatgaggg cggtggcggc ggccaccgcg gccaccgatt gcccgagggc gacggccacg
     9721 accgcgggcc ggtcggtccg ccatgccagc cgggtcgcct ggcccagaat ggtcggcagt
     9781 tcggtggtga cggcccggcc ggtcatcgcc agtgtccgct ggtggtgcac gtcgggcggg
     9841 ggcgggttgt tcgagctggt catgcggtcc atgtgtgccg cacgccgcgg cgtgcggcac
     9901 gaggtttccc atagcgatcc gggacccggc gcaggtcacg ccctatgagg cgtcaaactg
     9961 gcatccatcg atacacccct acgagtgagc cttcgaggcg tcagatctcc agggccggca
    10021 ggtagtgcca gccgtcgccg acgtactccc cgaccggttc gtccccgggt atccgggccc
    10081 aggcgtgata ctccaccggc ggtgccaccc gcgcacccac gcaccaggcc aggcgtcggc
    10141 cgcacagggc acacgccagg accgcgccga gcgaggactc caggcacgcg acccgcaccg
    10201 gccagccgcg gcccgcatgc cgcacggctt ccaccatcac ctgcgcccgc tcggcgggca
    10261 gaggacgccg gccgatgaag cgcgcggtcc gcgccgcgcg aacggtccac cggaacggca
    10321 accgcagcag caggacggcg gcggccaacc ccagccaggc aactgcccgc tgccggggag
    10381 taccggcccg cacggtccgg tacgactcga tcgaagtcac cgccaccacc tccgtccgcg
    10441 gcggcgcggc gcggcgagca ggccacggtc ggtcaagccg cgctcgactg ccagcaggtc
    10501 ctgttcggcc tgctcgcgcg gcacggcgaa ccggccggcg aactcctcga tcgcctgtcg
    10561 gcgttcctcg gtactcagca ggagtcggag cgcgacggcc gcggtaccgg acaggtgagt
    10621 ccaccgtccc gagcgttcgt cgagaagcgc cccggccgtg tcggtcagaa tggcgtgtac
    10681 tccgtcacgc agccgcatgg ctctgcgcct cccccggcga gtgcctgacc gacgaccacc
    10741 aagcggagac cgattcgacc tgccgcagcc acagctcggc ggcgaccgcg tagtgaatcg
    10801 cccccgcccc cgtgagccgc ccacccgcag cggaggccac atcgtcgagc acgccggagc
    10861 gcggcagcag ccccaggtcg gccaagcgag agttcgggcc caggagttca ctgatgaccc
    10921 gagcgtgccg ccgcagccct gcgtgtgcca ccccgtcgag gccgcctttg gtggtgcggc
    10981 ccagcacgaa gccgggcacc ggcccggtcg ggaacgcggc ggcgagcaag ggcttgtacc
    11041 ggtcggccgc gccccgctcg gccgcgtcga ttgagagaca ggtcctgacc acctcgttgt
    11101 ccagataggg ggcggccagg gtgaggccct ggctgcgggt gatggcgtgc catccagcca
    11161 ggctgccgcc gatccgggcc aggtcctggc gatcggacca gaccgacata cccggttcct
    11221 cgccgagcgt gtcagccacc gtgtccaccc ggtccgccag gagttcgcgg acctcagacg
    11281 acatccagcg cgcgcacggc gacagcacct ggcgcgcggc ggcttccgga gtggcaacca
    11341 cgacgctggg ctgcgcggca cgcaactcct cggccgcccg gcgccacccg ccggccacac
    11401 cgccgcgcgc cagcggcccg acgcgctgcc ataacgccag cgggctcatg cgccgtaccc
    11461 gggcgtgcgc caccgtgtgt cgccacgcct ctcgccgccg tccggctcgg tagaggtctg
    11521 cgagatagcc ggcggatgcg gagaggacga catcgccgcc ctcacccgtg aagtacacgc
    11581 ttccgccgtg gtcggcggcg accagctcca gttgggcgcg tttgatcctc gcggtcgcgc
    11641 tgtagagcgt cggctcgtcc gtctgcggca ccgatcgcgg gccctgtagg cccgcgtaca
    11701 tcaccgcgtc tgcgctgccc gcgaacacgt ggtgccgtac cccgggaacc acggccgcgg
    11761 tgcgccgggc gtacgccagg tcgtcgtcgc gcattcgcgg gtccgcatga gtcagcgcgg
    11821 tcaccggcac gtcttgagcg gcagcgaggc acaccagcgt ggtggagtcg agaccggcca
    11881 ggtcggcgac taccggtcgg ccgtccaggc gaacggagac cgcgtccgac agagccccgg
    11941 ccaccgccga cgccccctcc gccatgctca ccggccgagg acggctcggc tcgaagggaa
    12001 cggagtgtgc gcccccgggt tcgagcagga gcaggtgccc ggtggccact cggctgactc
    12061 ggtggaacag actccggctc cccgagatgt caggctgccc gagcgcgagc cgcgctgcca
    12121 gagcgatccg gtcgacccgg gcaccgtcca gacccgccag cggcatcgct gcggtcgccc
    12181 accacacacc ggcgtcgaac gggcgccagt acaccgagtg ctgcccggcc aggtcgccga
    12241 tcaccgcggt gacctggccc cgggtcgcga tcgccagata ggagccgggc caccgggtga
    12301 gggctcgcca ccggcccgcc cgcacatcgg ccaagccgga ctccagatcg cccggccggg
    12361 cgccgcacat gccgatgacc gtcagtccaa cgcccgccgt tccggtggtc cttacccgcg
    12421 cggccggcca cccgcacgtc cacgtgcccg ggcagccggg cacctcctgg ctgttcaccg
    12481 gcgctcgggc cggtggtttc tgtccgtgcc atcccgcaca ccactgcact gctactcccc
    12541 tcacacgctc ggtcggtgga acaggcgggc gccggcaccg cacgcgcggt accggcgccc
    12601 ggatcactca cgatgtggct ggctccgtca cagagcggag actcccgggg tcttctggcg
    12661 gtactcggtg ttgtcctgga cgtcgaagcc gttcttgccg agggtcacgt cggcgaccgg
    12721 gccgccgtcg gacaacgtcg gcggctggta ggcggcctga gtaggggtgg tgggctccgt
    12781 gctcacgggt acctccgtcg cataggcact gcggctcgtg gtccggcgct cgggccggtg
    12841 aaccgcggtg gggatgcctc acaccatggc cgtgcccggg cacccggagg aagcgccgcg
    12901 atgtgcccag gtgtgcccac cgtgtgccca ggtgttacca gcttccgcgc atggagcggt
    12961 cgccttctgc cgggcgggcg cgaatgcggg caccatggca tcgggcccac cggtaacggg
    13021 caggggggtg gagggaattg catctcgacg aacacccgct ggtgtatctg ctgcgtgtcc
    13081 acggctggtc agccaccgac tacctcaccc gcctcagtgc cgtccacgtc aagcttggct
    13141 acgggccgat cgccaaggac cgcaagcgga tcacccgatg gacccgttac aacgtcaccc
    13201 cggacatgcc ggcgcaacgg gcgatggccc atctccaccg catcccggaa gatgagatca
    13261 ccgcccgccc ctggccggaa tggctcaagc tcgcctgcat ccgcgaacgg caactgctca
    13321 gcgctgcctg gaccccggac acaaccctgc acctgttaga ccgcgtcgcg attggaggcc
    13381 cgatggaccg cagaggattc ctgctcgtca cggggatcac ccccgtcctg gccggggccg
    13441 tcaccgctca gccggccacc gctcacgcca ccggccgccg catcggcgcg gcagctcccg
    13501 agctgttcga gcagtccttg gcggtcctgc ggcgccagga tgaccagttc ggctccggcc
    13561 aggtccacac ctccgcccga gcccagctcc gcttgatcac cgcgagtttg cagaacgctt
    13621 cctacaccga ggccaccgga agacggctcc acggcgcggc agccgaggcc gcccgcatct
    13681 gtgcctggac cgcctatgac tccggccgcc acgcactggc cgaggagttc tacctggccg
    13741 cgctgcgggc cgccgccaca gcagccgatc ccgtcgtcac cgcgaacacg ctggcgttct
    13801 gggccatcca gcggtattcg acgggggacc cgcgcggtgc tgccgacctg atcgcccacg
    13861 ccctgaccct gaccggccgg atcggctcgg cccggatgga ggcgatgctt cacgcccggc
    13921 tcgcccgcgc ccacgccaag gccggagacg agcatgccag ccttcactcc caaggccacg
    13981 cactcgccgc ctacgaccgt gcccgggacc agtcaccaaa cgaggacccg gactgcgtgt
    14041 actgggtgag tctcggcgag ctgcggatgc tgcacggctc ctgcgccctc aacctcggcc
    14101 gaccccggcg ggcgctggcc gaattcgaga ccgctgccgg cgagtaccgc gaggacgact
    14161 tcccgcgcgc cgccgtcatc taccttgccc gcggtgccga agcacgcatc gccctggaag
    14221 atcttgacgg cgccgtggat atcgcccagc gcgccgtcga ccacatgggg ggcgtcacct
    14281 cggcccgcgg cacctccacc ttggacgacg tgcgccggca attccacgcc cacaggaccg
    14341 tgcccgtcgt cagcgagttc ctcgcccgaa ccgcctgacc ccgggcgccg gggagcccgt
    14401 tccctgcggt gtcccgcgcc ggacgcgccg ggcacacacg gccgttcacg ccgggcgggc
    14461 cgctggcgtg cgcgcccggg ctcggccgcc ggttccgcgg cggccgtcgg cgtcccgtgg
    14521 cggcccggtg ccgaccgggg cggggccaaa gcggggggcg gtggctctac cgaagatgcc
    14581 cgctgtcggt caaccctctt aggagtgagg gtagttgcgg acgtattgac gttattcatc
    14641 cttccgtgtg gcacttcaag ctctttgtct tatccgcgtc gtggaggggg cacctcacga
    14701 tcgacacggc gcgtccagtg cgcgtcagag agtcacttgg aggcatgatg cccgttcagg
    14761 tcagcactcg catctctccc gtccaggcgg ggtcggcgga gcgttccgcc ctcacctcgc
    14821 tgatctccga gcccgaggcc cccgtcagcg gtgcccccgt ctactcgccc gaggcggccg
    14881 gcttcctgct gctcctgatt ctgctttccc cgaagcagcc gtcggagccg cgcgacaagt
    14941 aacgccggtc gcggggccgc gcgttgcccc gccggttgcc agcgctcgtc acgaacggac
    15001 agaagctgac ggaaggtgag tcacctatgt cgtttccgga cccatcgccc cgcgcggtct
    15061 acgccgccga ggtggagagt ctggccgggc gcgtccggga cgccctcgcg ggcgccccgg
    15121 caccggcggg gcccgcgcgc cacgtcgaag aagccgagga cccgaaggcg gccctggccg
    15181 ccgtccgggt cctcggcccc gacgtgttcg ccccggccct gctggtcggc gcgcccttcg
    15241 gcccggccga ctgcgaggcc gtcaccgagg cgttccgcgt cttccctccc ggcccggacg
    15301 acaccgccga ggcggtgtgg cgcgaccacg ccacggccgc actcctgacc cggcacggcg
    15361 gcgacccggt ggcctcgggg ggcccgcccg tcgcccgacc cctggagcgc tggcggccct
    15421 ggacatcctg gctggccggg ctctccccgc tggcgctgcc gggagtgaac gggccgctgc
    15481 cccggcccga cctccgcgcg gcgcaggccc tggccatggg caccacgcgc gcgctgctgc
    15541 gccgcgacca tccgacggcg gcccgcctcg cccgctgggc cgcgttcgcg cacggccacg
    15601 gcgcctcgcc acctctcgac ctgctcgccg tgctcgacca cgtggacctg cacggcggca
    15661 cggcacggac cgcgctcgac accgcagtcg cccgccggct cgcggcggga gcagaaaggc
    15721 ggaccgcatg accgccccgt ccccccagtc accgccgccg tcctcgcccg ccgccgtgcg
    15781 caggacggcg cacgccctgt ccaccggggc gatcggctgg ctgcacgcga accgggagcg
    15841 cggtgcgttc gccccggatg tcaccgggga gttgaccgac ccggacagcg tgtacaagcc
    15901 gctgggcgag tccgtactcg ccgcgtccct ggtcctgcgc gagggcatcg cgtccccgac
    15961 cgaccggcgg gcggccgaga gcctgatgga gttcgcgtgg gcccagctgc gcgagggcga
    16021 tctgctgtac gagcggcagt tgcgctacat gatgatgacc gacccgcttg agctgtacac
    16081 gcacttcgcg cgggcggggt tccggcacga ccggctgcac gccctgttca accacctcgg
    16141 cggcctcacc tcgcgcggcg cggcggagca gctgcccaac cgccgcctcg cggtggccaa
    16201 cgcgtcgcgc gtcgcgggtc tcgaccggca ggccgactgg tccgtgctca cggacgcgac
    16261 ctggctcggc cagacgcccg agccgtgggc gatcgactgg atgacggcct actgcgtgac
    16321 ccacaccgtc ttccacgtca ccgactgggg cgggcggccc gacgccctct cgccccgcat
    16381 ccaggactac ctgggccggt ggctgccggt gtggatcgac atctggcagg agatccagga
    16441 gtgggacctg gtcgccgagc tgctgatcgt cgacgcctgc ctgcccgagc cgcgctccgc
    16501 ccccgaggtg tgggagcggc tggccgcggt gcagcgcccc gacggcctcg tgccgcgcaa
    16561 cggcgagcct gtcacggagg accccgacga ggcgttccgc gagcaccagc acaccacggt
    16621 ggtcgcggcc gtcgcgggca ccctggccct gtccaggcac cgcggcgccc gcgccctcgt
    16681 gtgacgcgcg tgtccgggct ggaccggcgg ctgtccgccg tcgcggacgc cgccggcccc
    16741 ccggccggga tcgcggtcgc cgtccgggcc ccgggcggcg acgcgacgct gtgccgcggg
    16801 accaccgacc gcaggggcgg cgcgcccgtg accgagcgca cccgtttcga ggtcgggtcg
    16861 gtcagcaaga cgttcaccgc gctgctgctg gccgagatgg cggagcgcgg ggatgtcgcg
    16921 ctcgacgacc cggccggcac gcgcggccac cgcgtcaccc tcgaacacct ggccacccac
    16981 acctccgggc tgccgcgcct gccgcccggc ctgctgcgca cagcgtggcg ctcctggtac
    17041 accaacccct acggccacta cccgcccgaa cggctgctgc ccgcgctggc ccgcacccgc
    17101 gtccgccggg agccgggcac gcgcgtgcac tactcgaact tcggggtcgg cctcctcggc
    17161 cgcctcctcg cggaggaggc gggcaccgac tacggaacgc tgctcaccgc ccgcgtgctc
    17221 gacccgctcg ggctgcgcga caccacggcg gaccgctccc tgccgcaggc cgtcgggcac
    17281 cggcacggcc gtccgctgcc gccctgggac atcccggccc tgccgggcgc gggcgcggtg
    17341 cgttccagcg ccgccgacct gctgcgctac ctcgccgcgc tgacaggccc cgacgccgcc
    17401 gtgcccggcg gcggcccgct gcgcgccgcg ctgcgcgagg tcgtgcggcc ccgcgtcaca
    17461 ggacctggcg gcccggcgct gccgctggcg tggagcacgc gggagcgccc ggggcacgtg
    17521 ctgtaccacc actcgggcgg cacgcggggc agcaccgcgt tcgccggctt ctgccccgag
    17581 cacggcgtgc acgtcgtggc cctggccgcc accgggccga cggtgcgcgg ccggttcatc
    17641 cagagcgcct acctcctgct gcgctccctg gcggccgagg cggcggagcg caccggcgaa
    17701 cgcggctgaa cgcccgcccc cgaagcgccg gttcgcgccg cctcgggcct gtggcagatc
    17761 tcgcgcccct cgcggcggcg cgcgggtcag tcgtggttgg cgaggaagag gagagcgagc
    17821 gtttcgtcgc cctcgcccag ggcctcgaag ccgtgcacct cgccgtagcg gcacaccggg
    17881 aaggagagca tgttggcgcc ggtctccgga tcgacgacct cgttgatccc atggctcgcc
    17941 ccggtgcggg cgtcttcgga cagcaacgcc cgcttcgccc tgcgtatcgc gccgtcctcg
    18001 tcaccgcgcc tggcgccctc gctccgcagg cacgcgtagc cgtcgaggta ctggcccacg
    18061 tcgtcgtagc cgtggctcca ccgcgtcgtg cgcaaccgct cgggccccgc gagggggatg
    18121 aacagcgtgt ccacgcgata ccgctccggg tcctcgtcct cccacccgct gggcacgccg
    18181 tcgttcacgt acacgggata ggtgccgtcc ggtacgcgat ggacgaacgc cccgttcccc
    18241 tcgttctcgc gttccgggct ggtccagcgc accacctcgc cgaccaccac gagatccccg
    18301 gcccaacgga cggcttgcgg cggatcgctg taccacccgc cgagcgagcc gggagcccac
    18361 ttggtcgcga tgaaacccgg cgcgaagtcc ttcatggcgc tgtcggcgcc catgcccgca
    18421 cacctcgcct cgtgttcgat tcttgttcgt tttcacgtgc gcggtgcact cttccacacg
    18481 ggcgaggttg cctcaactgc cgcacgatca gcagcgctcg gccgtgcccc gcggcgtcac
    18541 cctccgccgc cgcgcaccgg tccgagccgg ccgtgccccg ccgagacgcc gccgtccggg
    18601 ggctcggcgc atcatggagg catgcccgag ggagacacgg tcgcgcaggc cgcgcgccgc
    18661 ctgcgcgagg cgctggccgg gcaccggctg gtgcgcgccg acctgcgcgt gccgaggctg
    18721 gcgaccgcgg acctgcgggg ccgcctcgtg ctcgacgtgg tcccgcgcgg caagcacctg
    18781 ctgacgcgcg tcgagggcgg cctcaccctg cactcgcacc tgcggatgga cggctcctgg
    18841 cgggtcttcc cggccgggcg gcgctggacc ggcggcccgg cccaccagat ccgcgcggtg
    18901 ctcgacaccg gggcgcgcgt ggccgtcggc taccggctgc cggtgctcga cctgctgcgc
    18961 acggccgacg agccgcgcgt ggtcggccac ctcgggcccg acctgctcgg cgcggactgg
    19021 gacgcggacg aggcgctgcg gcgcctgctg gcggacccgg cccgcgaggt cggcccggcc
    19081 ctgctcgacc agcggaacct ggccggggtg ggcaacgtgt tcatggccga gctgtgcttc
    19141 atcgccgggg tcacgccgtg gacgccggtg ggcgaggtgg cggctcccga ccggctcgtg
    19201 gccgaggcca ggcggctgct cgtcgccaac cgcgaccggc ccgaccgcac caccacgacc
    19261 cgcacgcacc cgcgcgaacg cggtgtgcgc ggctcgccgg gaccgcgcct gtacgtgtac
    19321 gggcgggccg ggcggccctg cctgctgtgc ggcgcgaccg tgcgcaccgc caccgagtcc
    19381 cgcgaccggg ccgggcagga acgccccgcg ttctggtgcc cgcgctgcca gcggggcccg
    19441 gcgcccgcct gatctcccgc gccccgccac ccctgaacgc gaacgcgaac gcgcgtgcga
    19501 atatcgacgg cccggcaaca ggactgcacc gccgcgagct gggcacccgg agagcacaca
    19561 agcacggaaa gggcgagaaa gtggagatct ccggaattat cagcgcgatt gtgatcgggc
    19621 tcgtgatcgg agcgctggcc cggctggtcc tgcccgggcg tcagcgcatc ggcgtcctgt
    19681 ggacgatcgc cgtgggcatc atcgccgcgc tcatcggcac ggccctggca gccgcgctcg
    19741 gggtggccga caccgacggc gtggactggc tcgaactgct gctccagctc gcactcgccg
    19801 cgctcggcgt gacgctcctc gaccgcgtca aatcacgggc ctgacaccgc ctgacgccac
    19861 ggcccaccgc ggcccgccgc gaccgaccgg tcgcggcggg cccgcgcgtg cggaaggcgg
    19921 ccggagggcc acggattgcc ccagaagggc gtccaggcgg gcaccgccga tccactgctc
    19981 gaacgtggtt cccgggaaaa cggcgctcgc gagcggccca tcggccgtca cgttccgcga
    20041 catcccccgg cgaaagcacc ggccgccccc atacgccccc gtttgtatgt gaattgtgta
    20101 gccgtcccgc tacgatcggc agcatcgcgg aacgtgggcc gcggcctcgg cgcggccagg
    20161 ggggaggatc tcggcatggt cgacatcaat ccgcacgtcg acccgccgcc ggagcacggc
    20221 cgattgcgcg tggcccgtga cacgttggcg gccatcgcgg aactgcttga gggcccggcg
    20281 ctcgcgctgg cccaggcgga gggaccggcc ctgggggtgc ggaggctcgt ggaacgcatg
    20341 gacgacttca gtggtgaatg ggaacacggc gtcgcgcagc tcggcgagtg cgccgaggcc
    20401 gcggtacgcg cgctcgacat ggtcctgtgg tcgctgcccg cgcccccgga gccggcgcgc
    20461 ggcgacgcgc gggacggcgg cccgggcggc gcggcgggcc gcggcgcgtg cgacacgtgc
    20521 gacgcgtgcg gctcggacgg ggtgatcgcg gcatgagcgt ggtcaacggg cccggcgcgc
    20581 cgcgtggttc gcacccccgg ccgctgccac ccggcggcgg ccaggggccg gggcaggagg
    20641 cggactaccc ggccctcggc ttcgtgccct gcccggggga ccagccggtg gccgcgcaga
    20701 tcgcgcgcaa tgtgcgggag gccgccgcca ccctcggcac cgtcctcggc ctgctcgact
    20761 cggtcgtgcc gccgggggag tggcgcgggc ggcccgccgc cgccctcaag ggcttcgaac
    20821 gcggtttccg gcccaaggtg gccgcggcgc gcgaggcgtt cgccgccgtg gcggacgtgc
    20881 tggaggactg ggccgaccac atgcgcgagg cccagcagga cgcccgcgcg ctggaggccg
    20941 aggcgcgggc cgcgcgcgaa cgcccggggc tcgacgccgt ccgcgcccgc gcccgcgcgc
    21001 tcgcggccga ctacgacacc tacggcgcgt tcgtggccga acggctcggt gaggccgggg
    21061 acgccgcccc cgacaagccg ggctggctca ccggccttgc gcgggacatc gacggcctga
    21121 ccacgatgcg cccggcgccg tgaccgctcc ggcgccgccg ggcctcaggc cgggcgcggc
    21181 gccggttcga gcacctttcc cagcagcccc accagggtga gcaggtcgtc ggcgtccaac
    21241 cgggcgagcg ggctcagggc cagcgtcgcc tcgatcaccg cggaccgcac ccgccggccg
    21301 tccgccgtca gcgtgacgac gcgcgaccgg cggtcggcgg ggtcggcgga acgctcgacg
    21361 agcccccggc cgccgagctg gttcatgacg aagctgaggt tgggcgcgtt gcagtgcagc
    21421 cgaccggcca actccttcat cgagggcggc gcttcggccg ggtcgatcgc ccacagggcc
    21481 tgggcggtcg cgtgtgtcaa gccgtgttcc gccagcacgc tctcgacccg gtcgctggtc
    21541 cgcatgaaga gttcgtggct catcaccacc gccgcttcaa gggagcttcg cgtcatggcc
    21601 tcaccctagt actggggcgg tgcacggccg ggctgtcggc caggtgggcc gttggagcgg
    21661 tcatgggtgg ggacctcgct gatgtcaggt cgcggggaga tcaactggat gctgtgcgtg
    21721 agcggttcgt gcaccggtgc accaggtcgg agccgaggga gtcggtgtcg gcccgtacgc
    21781 ggggtactga gcgagaggtg tccgggcggg cgcacgttcc cgagaagagg tccaggagcg
    21841 gaacagcggg ccccgtcaag gggatgggta gcatcgcggg gtaccgcgtg ccgctctgag
    21901 aacagcagga gacctcgtga gtgtcgagca gaacaaggag atcgcccgca ggctggtgca
    21961 gggcttctcc gtggatggcg acatcgacga aaccttcgct ctcctccacg aggacgcggt
    22021 gtggacggtg atggcgcatc ccgcgtcctt cggcgcttcg ggcgacatgt cgaaggcgca
    22081 gttcgtggag cacatgaagg gcttccgtgc cgtcactccg aacggactcc gcatgactgt
    22141 gaccggagtg acggcagagg gtgatcgcgt cgccgtggag gccgagtcgt cgggcacgct
    22201 gggcaacggg aagacgttcg gccaggtcta ccacttcctc ttcgagatca gggacggcaa
    22261 ggtcatggtg gccagggagt acctcgacac ggcgcgtgga gcagctgtct tcggcagctg
    22321 agccgattcc tgccctgcac gcgccgacgt ccgggcggag ccgctgtcgg gcggactgcg
    22381 gcttcagtac ggcagcggtg cttgccgtgg ctgccggcca gttcaggggt ggtgtcccgc
    22441 aggacctagc cccgtccctt cgagcctcga accgtcccgt ccccgcgcgg cccgccgtcc
    22501 ccgcgcggct cggcgcccgc ccccgcgcgc accggccggt agtggtcgtg ggcggattcg
    22561 agcaggccct cgccgtgcgc cgcgccgtgc aaccccgccc gcaccgc
//
