LOCUS       NZ_CP084541            13188 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces marincola strain SCSIO 64649 chromosome, complete
            genome.
ACCESSION   NZ_CP084541
VERSION     NZ_CP084541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Strepomyces indimicinicus sp. nov., an antibiotic producing
            actinomycetes isolated from the marine environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Sciences, 164 Xingang West Road, guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. V6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 444.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020410765.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,763
            CDSs (total)                      :: 5,689
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 74
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 21 of 77
            Pseudo Genes (incomplete)         :: 60 of 77
            Pseudo Genes (internal stop)      :: 2 of 77
            Pseudo Genes (multiple problems)  :: 6 of 77
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:57:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4100549
            Orig. end                         :: 4113737
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..13188
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="24"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13188
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13188
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8188](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..8188)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    976..990
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            complement(1360..2124)
                     /locus_tag="LC193_RS18065"
                     /old_locus_tag="LC193_18065"
     CDS             complement(1360..2124)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014628241.1"
                     /locus_tag="LC193_RS18065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18065"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_226075504.1"
                     /transl_table=11
                     /translation="MRGRAEKTEVRRRTGGAAEGVGSAGAVVRAAGVVVEVPGRRLADG
                     LDLEVGAGEAVAVMGPSGSGKTTVLNALAGLVPLSGGGVAIAGEPISELSADRAAALRL
                     AHIGMVFQFGELIPELSVRENVALPALFAGRGDATGRADALLDLVGLAGYGARAPEELS
                     GGEAQRVAIARALVCGPRVVLADEPTGALDEDNARRVTDVLLRSCREQGTALLVATHDA
                     AVAAAMDRTLLLRGGRLHPRASTAASGAGEGR"
     misc_feature    complement(1843..1845)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(2229..3278)
                     /locus_tag="LC193_RS18070"
                     /old_locus_tag="LC193_18070"
     CDS             complement(2229..3278)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006027.1"
                     /locus_tag="LC193_RS18070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18070"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_404819540.1"
                     /transl_table=11
                     /translation="MASGAQEAPEADERNAGGDPRRPVTIAYIAESAGVSVPTVSKVIN
                     GRSGVSDDTRARVEELVNRHGYRKPPGSRNKVVELVFRELRSMWAVEIIRGVERVARER
                     RVGVMVSEFGLHDSNPMTMDDTVGRRPNCVLSVAQLSAAEREQLSAKGIPFVVFDPTTE
                     LPDDVPFVGATNWRGGHAATRHLIELGHRRIAMISGPDEVLCCRARLAGYGSALAEAGL
                     AADPGLVTRVPLTREDGHAAARALLTRPDRPTAVFTANDLQALGVYQAAREIGLSVPED
                     VSVVGFDDLPVVAWVDPPLTTVHQPLTEMAVAATELALALGRGEKAPQLGLEIATTLVV
                     RDSTAPPKG"
     gene            complement(3547..5004)
                     /locus_tag="LC193_RS18075"
                     /old_locus_tag="LC193_18075"
     CDS             complement(3547..5004)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468373.1"
                     /locus_tag="LC193_RS18075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18075"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_226075506.1"
                     /sec_met_domain="Aldedh (E-value: 1.6e-33, bitscore: 114.4,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHPTTTPDELQALLAGAAAAAPDWAARGPADRASALTAVADALD
                     EHAGALLPLAREESHLPDGRLAGELKRTTFQLRLFAALLRDGAYLDARVDHADPDWPMG
                     ARPDIRRVLVPLGPVLNFAAGNFPFAFSVAGGDTAAALAAGCPVLVKVHPGHPRLSART
                     GEVVALALRDAGAPEGVFGLVHGVDEGVTALRDPRVKAASFTGSVAGGRALFDIACSRP
                     EPIPFYGELGSVNPTFVTRAADAARAEEIAEGFVGSFALGAGQFCTKPGVLAVPEDSAV
                     LRRLRSAALPGPAPMLSARFAEGYARRLGELAGHEAVRPLAANESAQADAPAPALLTAG
                     IEDVLAGGGELLAECFGPAALVVTYAEESQLVALARALDGQLTATVVGEDDDAIVPELV
                     PLLAERAGRVLWNQWPTGVSVTYAQQHGGPYPATTAPTTTSVGTAAIARFLRPVAYQGF
                     PDHLLPEALREGNPQGLPRLVDGTPAR"
     gene            complement(5001..6638)
                     /locus_tag="LC193_RS18080"
                     /old_locus_tag="LC193_18080"
     CDS             complement(5001..6638)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014053689.1"
                     /locus_tag="LC193_RS18080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18080"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_226075508.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.7e-23, bitscore:
                     81.7, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 5.6e-06, bitscore:
                     25.1, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPAPRPAGPVFDTAVVGAGPAGLAAAVAAADAGLRVALIDAAAQ
                     TGGQFWRHRDERAAAERAGGASAASAASPAFPAFPAFPADESAGQHDWATFTRLRGRLA
                     RHVGAGRVHHLPLHQVWTVDRAGAAPFTLRLTPVLPGHPDGATREVAARALILCPGGYD
                     RQLPVPGWTLPGVMAAGGVQALLKGHGTLAGRRAVVAGTGPFLLPVATGLARAGARVLA
                     VCEAARPTRWLRRPLDAARTPGKALEGAGYAAALLRHRVPYLTRTAVTRVHGEDEVDGV
                     TLERIDGAGRIVPGRGRRLDADLVAFGWGFTPSLELVLAVGAGTRRGEDGSLVAAVDRV
                     RRTTVPGVYVAGEATGVGGAAKAVAEGELAGLTAAVDQGRPASRGRGRVLLGRIARAEA
                     FASAMHHAHPVPERWHEWLTRDTVVCRCEEVTTGELRDVQDDLGADDPRTAKMLARPGM
                     GWCQGRVCGFATACLLASRAGRPAEADDLRPLAKRPLAAPVPLGELAALAPLAPPEPAP
                     GPAAEQASGPPGGATDPPRPGTDPEEAP"
     gene            complement(6635..7021)
                     /locus_tag="LC193_RS18085"
                     /old_locus_tag="LC193_18085"
     CDS             complement(6635..7021)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038322.1"
                     /locus_tag="LC193_RS18085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18085"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_226075512.1"
                     /sec_met_domain="Fer2_4 (E-value: 2.4e-24, bitscore: 83.6,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPYAHDHEHDHDREAGRGSRRDPAADRLELTFDGTPLSARPGQSV
                     GAALTEHGIRAWRGTREKGAPRGLFCGIGVCWDCLITVDGVPNQRACLVPVREGMDLSS
                     TPPGLPLPPEPAPEGGAAAEGGRP"
     gene            complement(7028..8188)
                     /locus_tag="LC193_RS18090"
                     /old_locus_tag="LC193_18090"
     CDS             complement(7028..8188)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175745.1"
                     /locus_tag="LC193_RS18090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18090"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_226075514.1"
                     /sec_met_domain="DAO (E-value: 7.4e-68, bitscore: 228.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARPDLVVVGAGVVGAASAYFATLAGLRVLVLDRGHVAGGTSSR
                     GEGNLLVSDKEAGPELDLALLSQRIWREELGEFGPLWEFDSKGGVIVAATPASAEALTG
                     LTEGQRAFGVTAVDLDAAELPDYEPFLSRAMVAGAYYPQDAQLQPMLAAAHLLRLARLR
                     GADVRTGTEVTGLLRDGERVTGVRTPRGDVAAGAVLNAAGPWGGAFAALAGVRLPVLPR
                     RGFVLVTEPLPPTVRHKVYAAEYVGDVASSDAALQTSPVVEGTESGTILIGASRERVGF
                     DSTLSPHVLGALAANALALFPSLAGVRALRAYCGFRPYCPDHLPVIGPDPRAPGLWHAC
                     GHEGAGIGLAAGTGWLLAQAMTGGNTDLDLGPFAPERFDSATTGEG"
     gene            complement(8185..8934)
                     /locus_tag="LC193_RS18095"
                     /old_locus_tag="LC193_18095"
     CDS             complement(8185..8934)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850115.1"
                     /locus_tag="LC193_RS18095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18095"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_226075517.1"
                     /transl_table=11
                     /translation="MTTPNSSSNFTVLKKRENLRESVAHALRAAIVSGEMEPGVVYSAP
                     TLSARFGVSATPVREAMLDLVREGMVASVPNKGFRVTKISEADLDHITELRLLIEPPTI
                     RRVSPLIPAADFPRLRRLADEIVDAAEQADLIRYTEADRRFHLTLLAYSGNPRLVDTIS
                     QLRSQTRLLGLASLAGSGELRDSAEEHLRLMDLIQAGDGAGAEELMRRHIGHVRGKWAG
                     DAGSGKDTGDERDAGGGDSAGSTGRGS"
     gene            complement(9041..10042)
                     /locus_tag="LC193_RS18100"
                     /old_locus_tag="LC193_18100"
     CDS             complement(9041..10042)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019763263.1"
                     /locus_tag="LC193_RS18100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18100"
                     /product="proline racemase family protein"
                     /protein_id="WP_226075520.1"
                     /transl_table=11
                     /translation="MRSKRVFHSVESHTEGMPTRVITGGVGTIPGSTMAERRQWFIDNS
                     DDVRTLLMYEPRGHAAMSGAILQPPTRPDADVGVLFIEVSGLLPMCGHGTIGVATVLVE
                     TGMVEVTEPVTTIRLDVPAGLVTADVEVVNGAARSVTIRNVPAFSAALDQRVEVPGLGS
                     VGYDLAFGGNFYALVRLAELGLPFERAAKDELLAAGLAVMRAINAQDPPRHPERPDIHG
                     CHHVYLEAPGSTAAHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGLLGLHQDFVNES
                     FIGSRFTGRLVAETEVAGLPAVVPTITGRAWVTGTSQFHLDPEDPFPAGFLL"
     misc_feature    complement(10021..10035)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 15.81"
                     /tool="antismash"
     gene            complement(10196..11101)
                     /locus_tag="LC193_RS18105"
                     /old_locus_tag="LC193_18105"
     CDS             complement(10196..11101)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175748.1"
                     /locus_tag="LC193_RS18105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18105"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_226075523.1"
                     /transl_table=11
                     /translation="MTAARQPWRGVHVATAFPFDDDLAADFDGFAEHVAWLAEQGCDGV
                     CPNGSLGEYQSLSDAERARVVETAVAAAPEGFTVMPGVAAYGVLQSRRWIEQAAEAGAH
                     SVLLLPPNAYRADERTVLAHYREAAKAGLPVVAYNNPFDTRVDLTPALLAELHAEGLIV
                     AVKEFTGDVRRAYEIRELAPELDLLIGADDVLLELGLAGAVGWIAGYPNALPSTSMELY
                     RLATSGDPADISRALTLYRELHPLLRWDSKPEFVQAIKLSMDVAGRKGGPCRPPRSPLV
                     PEAEAAVRATTEAVLAAGHR"
     misc_feature    11138..11154
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.14"
                     /tool="antismash"
     misc_feature    11142..11152
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    complement(11148..11158)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    11246..11262
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 14.74"
                     /tool="antismash"
     gene            11286..12308
                     /locus_tag="LC193_RS18110"
                     /old_locus_tag="LC193_18110"
     CDS             11286..12308
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024799.5"
                     /locus_tag="LC193_RS18110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_18110"
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_226075525.1"
                     /transl_table=11
                     /translation="MRQTPGKVLAVVAGVVVLAPGCAPDTSTAEGEYRVAVLAASAQNG
                     YNQAVYDGVVAGAEELGLTVDVKILDGGFDSTTQLSQLQTAATVGGYDGVIVVPHDGPS
                     LAGAFPLANSVPVITVLNPIGPDVDDMEPQVEGVVSTVAVPPSDAAARQAEGVVDHCAD
                     LDPCKVTLVVGDLSSPLDIARRDAYRGVLGEHANIEVVSTVEGNYDRYQSLTAVSNSLQ
                     SNRDVDVILASADQMTLGAELALENAGIAPESVYLTGGGGTTEAVRAVREGRWTANYLN
                     FPVSMGAAAMEQLANAMTGRPVETVVNADTVGPEGVEPYATRETLAGPEAEDFTGEWNG
                     "
     misc_feature    complement(13030..13048)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 24.28"
                     /tool="antismash"
ORIGIN
        1 cgtgctccac cgctccgcgc acttcgacgg cctcggcggt ggggtcgggc ggaacgggcg
       61 ggtcgagttg ccgcaccgtg gtggaccagg cggcgatgac gggactcagc accagcaggg
      121 cggcgatccc gtacaggggg cggacggccg agcgggggtc gtactggagg cgccgccccg
      181 cgagcatgcg ggcgggcgcg gtggcgccgc gcgcgatgcg ttccccggcc cggcgcgcga
      241 tcaccggcag ggccagggga acgccggccg ccagcaggat cgcgcccgcc agggtggtgg
      301 tggtcgatga ggtgccgtcg cggaagaagg cggcggccag cagggcgagg ccggcggcga
      361 cgggcgcggt gcgcgccagc gccaggcgcg gccgtccggc tcgcggccgg ggcgtcgcgg
      421 cgtgctcccc ggggcgccgc cgcctctcac ccgccaccgc caggagcgcg aacagcacgg
      481 cgagaacggc caggacggcg gtgaaggacc acaagggcgg gacgagcgcc ccgtcggcca
      541 ccggccggtc gaccaccggg agagcggtga cccgcgggcc tgccagggcc cagaccaggc
      601 cgcccagggc caggcccggc aggacgatga acgcggcctc cgcgacgacc aggcgtcggc
      661 ggcggcggcg cggaacgccc agggcgcgca gcagcgcgag ccggtgggcg cgcggcggcg
      721 ccgacacggc ggccgcggtc gcggccagca gcaccagggg aaggacgatc agggcgctga
      781 tggccagggt caggccggtg aggtccagtt cggtgtcctc gccgatcgtc atgaggccgc
      841 ggccgaaccc ggtgaccggg acggcgccca tggccccgtc ctcgggcatg agccggtagg
      901 ccagcagctc tcccggatgc cgtaccccct cgtcggtgag gacccgggcg ttcgggaaac
      961 gttccgccaa ctccgggtgc tgttcggcca gttcggcgag tcctggggag acggcccagc
     1021 cgccgggctc gggccaggag gccaggccgg ggggcagcgc ccgggggtcg gtttcgtcca
     1081 ccgggtcgaa ccacaccacc ggatagctcg tcgtgcccca gctgtcagtg tgtcggtcga
     1141 cgcgcagcac cgcctcctcg gcggaagtgg tcaactccat cgtcctggcc tcgaagcgct
     1201 gccgctcctc gcccagcatg tgcagcaggc cggcggtgaa cagcgcggtg accgcgacca
     1261 cggccgccgt cgtgcccagc aggaccacgc gcagccgctg ccgcggatgg ggggagcgga
     1321 ccagccgcag ggccagccgc cacgtcgtcg ccgtcgcgtt caccggcctt ctcccgcccc
     1381 cgacgcggcc gtcgaggccc gcgggtgcag gcgaccgccg cgcagcagca gggtgcggtc
     1441 catcgcggcg gccaccgccg cgtcgtgggt cgcgacgagc agcgccgtgc cctgttcgcg
     1501 gcaggaccgc agcagaacgt ccgtgacccg ccgggcgttg tcctcgtcca gcgcgccggt
     1561 cggctcgtcg gccagcacca cgcgcgggcc gcacaccagc gcccgcgcga tggccacccg
     1621 ctgcgcctcg ccaccggaca actcctcggg cgcccgggcg ccgtacccgg caaggccgac
     1681 caggtcgagc aacgcgtcgg cacgcccggt ggcatcgccc cggccggcga acagcgccgg
     1741 cagggcgacg ttctcccgca cactcaactc cggtatcagc tccccgaact ggaacaccat
     1801 gccgatgtgc gccagccgca gcgccgccgc acggtccgcg gataactcgc tgatcggctc
     1861 gcccgctatc gccacgccgc cgccgctcag gggcacaagg ccggccaacg cgttcagcac
     1921 cgtcgtcttg cccgagcccg acggccccat cacggcgacg gcctcacccg cgcccacctc
     1981 caggtcgagc ccgtccgcga ggcgccgccc cggcacctcg acgaccaccc cggccgccct
     2041 gacgaccgcc ccggcggaac ccaccccctc ggcagccccg ccggtccggc gccgaacctc
     2101 tgtcttctcc gcacgcccgc gcatcgcgcc cctccccttg tgtgtccatc aggacacggc
     2161 acgctaccgt cccgccgccg gcgacgcgcc cgcgggcgtt catcgtccgg ggcgtccgcg
     2221 aggcccgttc accccttggg cggggccgtg ctgtcgcgga cgaccagggt cgtcgcgatt
     2281 tcgagcccga gctgcggcgc cttctcgccg cgaccgaggg cgagcgccaa ctcggtggcc
     2341 gccacggcca tttcggtcag cggctggtgg accgtcgtca gcggcggatc gacccaggcc
     2401 acgaccggca ggtcgtcgaa gccgaccacg ctcacgtcct cgggcacgct cagcccgatc
     2461 tcccgcgcgg cctggtagac gcccagggcc tggaggtcgt tcgcggtgaa gacggcggtg
     2521 ggccggtcgg ggcgggtcag cagcgcgcgg gcggcggcgt ggccgtcctc gcgggtcagc
     2581 ggaacgcggg tcaccaggcc ggggtccgcc gcgaggccgg cctcggccag ggccgagccg
     2641 tagccggcca gccgcgcgcg gcagcacagc acctcgtccg ggccgctgat catggcgatg
     2701 cgccggtggc ccaactcgat caggtgccgc gtggccgcgt ggccgccgcg ccagttggtc
     2761 gcgcccacga acgggacgtc gtcgggcagc tcggtggtcg ggtcgaagac gacgaacggg
     2821 atgcccttcg cgctcagttg ctcgcgttcg gcggccgaga gctgcgccac cgacagcacg
     2881 cagttcgggc ggcgtccgac cgtgtcgtcc atggtcatgg ggttcgagtc gtggagaccg
     2941 aactcggaga ccatgacgcc gacccggcgt tcgcgcgcca cccgctcgac accgcggatg
     3001 atctccaccg cccacatgct ccgcagctcg cggaagacga gctccacgac cttgttgcgg
     3061 gagccgggcg gcttgcggta cccgtgccgg ttgaccagct cctcgacgcg agccctggtg
     3121 tcgtcggaca ccccggacct gccgttgatc accttcgaca cggtgggaac cgacacgccc
     3181 gccgactccg cgatgtacgc gatggtgacc ggccgccgcg ggtccccgcc cgcgttccgt
     3241 tcgtccgctt ccggcgcttc ctgtgccccc gatgccagcg gctgctcgtc cgtcacgatc
     3301 gccttcctcc gtccggcgga ggcgccattg tggcactcgg gcagcccgcg ggccagatac
     3361 tttctccgct gagcggcgga aagtttctcc cgaagccgtc gacaggcggc ggccccgcac
     3421 cagcctcgcc gcggcgggaa gggccgctgt gcggcgcggg ccacacctac gacgccgagt
     3481 tggcgtccat ggacacccgg tccccggcgg gccggaccac cgaggccgtc cgtgcgccgc
     3541 gcggggtcac cgcgcgggcg tgccgtccac taggcgcggc aggccctggg ggttcccctc
     3601 cctcagcgcc tcgggcagca ggtggtcggg gaagccctgg taggcgacgg ggcgcaggaa
     3661 gcgggcgatg gcggcggtgc caaccgaggt ggtggtcggc gcggtggtgg ccgggtaggg
     3721 cccgccgtgc tgctgggcgt aggtcacgga aacgccggtg ggccactggt tccacagcac
     3781 ccgcccggcc cgttcggcga gcagcggcac cagctcgggg acgatcgcgt cgtcgtcctc
     3841 gccgacgacg gtggcggtga gctgcccgtc gagcgcgcgc gccagggcca cgagttggga
     3901 ttcctcggcg taggtcacca cgagggcggc ggggccgaag cactcggcca gcagctcacc
     3961 gccgccggcg agcacgtcct cgatgcccgc cgtgagcagc gcgggcgcgg gcgcgtcggc
     4021 ctgggcgctt tcgttcgcgg ccagcgggcg gaccgcctcg tgcccggcca gctcgccgag
     4081 cctgcgcgcg tacccctccg cgaaccgcgc ggagagcatg ggtgcggggc cgggcagggc
     4141 ggccgaacgc agccgccgca gcaccgccga gtcctcgggc accgcgagca cgcccggctt
     4201 ggtgcagaac tggcccgcgc ccagcgcgaa ggagccgacg aagccctcgg cgatctcctc
     4261 ggccctggcg gcgtcggccg cgcgcgtcac gaaggtcggg ttgacgctgc ccagttcgcc
     4321 gtagaacggg atgggctcgg ggcgggagca ggcgatgtcg aacagggcgc gcccgccggc
     4381 gaccgagccc gtgaaggagg ccgccttcac gcgcgggtcg cgcagcgcgg tgacgccctc
     4441 gtccacgccg tggaccaggc cgaacacgcc ctcgggcgcc ccggcgtccc gcagggccag
     4501 ggcgacgacc tcgccggtgc gggcggacag ccgcgggtgt cccgggtgga ccttgaccag
     4561 cacggggcag ccggcggcga gcgcggcggc ggtgtccccg ccggccacgc tgaaggcgaa
     4621 cgggaagttg ccggcggcga agttgagcac aggaccaagc ggcaccagca cgcggcggat
     4681 gtcggggcgg gcgcccatgg gccagtcggg gtcggcgtgg tcgacgcggg cgtcgaggta
     4741 ggcgccgtcg cgcaggagcg cggcgaacag ccggagttgg aacgtggtgc gcttcagctc
     4801 gcccgcgagc cggccgtccg gcaggtggga ctcctcccgg gcgagcggca gcagtgcgcc
     4861 ggcgtgctcg tcgagggcgt cggccaccgc ggtcagggcg ctggcccggt cggccgggcc
     4921 gcgcgcggcc cagtcagggg ccgccgcggc ggccccggcg agcagcgcct ggagttcgtc
     4981 gggggtggtg gtcgggtgcg tcatggtgct tcctcggggt cggttccggg gcgcgggggg
     5041 tccgttgcgc cgccgggcgg tcctgacgcc tgctccgcgg cggggcccgg cgcgggttcc
     5101 ggcggcgcga gcggcgcgag cgcggcgagt tcgccgagcg gaacgggcgc ggccaggggc
     5161 cgcttggcga gcggacgcag gtcgtccgcc tcggcggggc gccccgcgcg ggacgcgagc
     5221 aggcacgcgg tcgcgaaccc gcacacccgg ccctggcacc agcccatgcc cggcctcgcc
     5281 agcatcttgg ccgtgcgcgg gtcgtcggcg ccgaggtcgt cctggacgtc ccgcaattcg
     5341 cccgtagtga cctcctcgca gcggcagacg acggtgtccc gggtgagcca ctcgtgccag
     5401 cgctcgggca ccgggtgggc gtggtgcatc gccgaggcga acgcctccgc cctggcgatc
     5461 cgcccgagca ggacgcgtcc ccggccgcgg gaggcggggc gcccctggtc gacggcggcg
     5521 gtcagcccgg cgagttcgcc ctcggccacg gccttggccg cgccgcccac gcccgtcgcc
     5581 tcgcccgcga cgtacacgcc gggcacggtg gtgcgcctga cccggtcgac ggcggcgacc
     5641 agcgagccgt cctcgccccg cctggtcccg gcgccgacgg cgaggacgag ttcgagcgag
     5701 ggcgtgaagc cccagccgaa cgcgacgagg tcggcgtcga gccgccggcc gcggccgggg
     5761 acgatccggc ccgcgccgtc gatccgctcc agggtgacgc cgtcgacctc gtcctcgccg
     5821 tgcacgcggg tgacggcggt gcgcgtcagg tacggaacgc ggtggcgcag cagggccgcg
     5881 gcgtagcccg cgccctccag ggccttgccc ggcgtgcggg cggcgtcgag cggtcggcgc
     5941 agccagcggg tggggcgcgc cgcctcgcag accgcgagga cccgggcccc ggcccgggcg
     6001 agcccggtgg cgacgggcag caggaagggg cccgtgccgg ccaccaccgc gcggcgcccg
     6061 gcgagcgttc cgtggccctt gagcagggcc tgcacgcccc cggccgccat cacgccgggc
     6121 agcgtccagc cggggacggg gagttggcgg tcgtagccgc cggggcacag gatcagcgcg
     6181 cgggcggcga cctcacgcgt cgcgccgtcc gggtgtccgg gcagcacggg ggtgagccgg
     6241 agcgtgaacg gcgcggcacc cgcgcggtcg accgtccaga cctggtggag cggcaggtgg
     6301 tggacgcggc cggcgcccac gtgccgggcg agccgcccgc gcagccgggt gaacgtggcc
     6361 cagtcgtgct gccccgcgct ctcgtccgcc gggaacgccg ggaacgccgg gaacgccggg
     6421 gaggcagcgg acgccgcgga cgcaccgccc gcgcgctcgg cggcggcgcg ttcgtcccgg
     6481 tgccgccaga actggccgcc ggtctgcgcc gccgcgtcga tcagggcgac gcggagaccc
     6541 gcgtccgccg cggcgacggc cgcggcgagc ccggcgggcc ccgcgccgac gaccgcggtg
     6601 tcgaagacgg gaccggcggg ccggggggcg ggggtcacgg cctgccccct tccgccgccg
     6661 ccccgccctc gggagccggc tccggcggga gcggcagccc cggcggggtg ctcgacaggt
     6721 ccatgccctc gcggacgggc accaggcagg cgcgctggtt cggcacgccg tccacggtga
     6781 tcaggcagtc ccagcagaca ccgatgccgc agaagaggcc gcgcggcgcg cccttctcgc
     6841 gggtgccgcg ccaggccctg atgccgtgct cggtgagcgc ggcgcccacg ctctgccccg
     6901 ggcgcgcgct caggggcgtt ccgtcgaagg tcagctcaag gcggtcggcg gccgggtccc
     6961 ggcggctgcc gcgaccggct tcccggtcgt ggtcgtgctc gtggtcatgc gcgtacggca
     7021 tgggagttca cccctctcct gtggtcgcgg agtcgaaccg ctccggcgcg aagggcccga
     7081 ggtcgagatc ggtgttcccg ccggtcatgg cctgggcgag cagccagccc gtgccggcgg
     7141 ccaggccgat ccccgcgccc tcgtgcccgc acgcgtgcca cagcccgggc gccctggggt
     7201 cgggcccgat caccggcagg tgatcggggc agtacggccg gaacccgcag taggcgcgca
     7261 gcgcccgcac cccggccagg gacgggaaca gggcgagcgc gttggccgcc agggcgccca
     7321 gcacgtgcgg tgagagcgtg ctgtcgaagc ccacccgctc cctgctggcc ccgatcagga
     7381 tggtgcccga ctcggtgccc tccacgacgg gcgaggtctg gagcgccgcg tcggaactcg
     7441 ccacgtcgcc gacgtactcg gccgcgtaga ccttgtgcct gacggtcggc ggcagcggct
     7501 cggtgacgag cacgaacccg cggcgcggca gcaccggcag ccgcaccccg gccagtgccg
     7561 cgaacgcgcc gccccagggg ccggccgcgt tcaggacggc gcccgcggcc acgtcccccc
     7621 gcggggtgcg caccccggtg acccgctcgc cgtcccgcag caggccggtg acctcggtgc
     7681 ccgtgcgcac gtccgcgccc cgcagccggg ccaggcgcag caggtgggcc gcggcgagca
     7741 tgggctggag ctgcgcgtcc tgcgggtagt aggcgccggc gaccatggcc cgggagagga
     7801 acggctcgta gtcgggcagc tcggcggcgt ccaggtcgac cgcggtcacg ccaaaggcgc
     7861 gctgcccctc ggtgagtccg gtgagcgcct cggcgctcgc gggcgtggcg gcgacgatga
     7921 cgccgccctt gctgtcgaac tcccacagcg ggccgaactc gcccagttcc tcgcgccaga
     7981 tccgctggga cagcagcgcg agatcgagtt ctggacccgc ctccttgtcg gagaccagca
     8041 ggttgccctc gccccggctt gaggtgccgc cggcgacgtg gccgcggtcg agcaccagga
     8101 cccgcagccc cgccagggtc gcgaagtagg cgctggccgc gccgaccacg ccggcgccga
     8161 ccacgaccag gtcggggcgg gccgtcacga gcccctcccc gtgctccccg cgctgtcccc
     8221 gcccccggcg tccctctcgt ccccggtgtc cttgcccgag ccggcgtcgc ccgcccactt
     8281 gccgcggacg tgcccgatgt ggcggcgcat cagctcctcg gcgccggccc cgtcgccggc
     8341 ctggatcagg tccatcagcc gcaggtgctc ctcggccgag tcccgcagct ccccgctccc
     8401 ggccagcgag gccagcccga gcagcctggt ctgcgaccgc agttgggaga tcgtgtccac
     8461 cagccgcggg ttgccgctgt aggcgagcag cgtcaggtgg aaccgccggt cggcctccgt
     8521 gtaccggatc aggtcggcct gctccgcggc gtcgacgatc tcgtcggcca gccgccgcag
     8581 gcgggggaag tcggccgcgg ggatcagcgg gctcacccgc cggatggtgg gcggctcgat
     8641 gagcagccgc agttcggtga tgtggtcgag gtccgcctcg gagatcttgg tgacgcggaa
     8701 gcccttgttc ggtacggagg cgaccatgcc ctccctgacc aggtcgagca tggcctcgcg
     8761 cacgggcgtg gccgagacgc cgaaacgggc gctgagcgtc ggcgccgagt agaccacgcc
     8821 aggctccatc tccccggaga cgatcgccgc gcgcagggcg tgcgcgacgg actcgcgcag
     8881 gttctcccgc ttcttgagca cggtgaagtt cgatgacgag ttgggagtgg tcatggcacc
     8941 ttttcgggcg ttctctcggc gtgcttctgg cggatgtcgg ccgctcgcgc ggtcacgtgc
     9001 ggcggttcgc ggcggccggg caacggcccg gccccgcggg ctacagcagg aatcctgcgg
     9061 gaaacgggtc ctccgggtcg aggtggaact gcgacgtgcc ggtgacccag gcccgcccgg
     9121 tgatggtggg gaccacggcg ggcagcccgg cgacctcggt ctccgccacc agccggccgg
     9181 tgaaccggct gccgatgaac gactcgttca cgaagtcctg gtggagtccg agcaggccgc
     9241 gggcgtgcag ctgggccatt ctggcgctgg tccccgtccc gcatggcgag cggtcgaacc
     9301 atccggggtg gatggccatg gcgtgccggg agtgcgcggc ggtcgagccc ggcgcctcca
     9361 ggtagacgtg gtggcagccg tggatgtcgg gccgctccgg gtgccgcggc gggtcctgcg
     9421 cgttgatggc gcgcatgacg gccagcccgg cggcgagcag ttcgtccttc gccgcccgtt
     9481 cgaacggcag gccgagttcg gccaggcgca cgagagcgta gaagttcccg ccgaacgcga
     9541 ggtcgtagcc gacgctgccc aggccgggca cctcgacgcg ctggtcgagg gcggcggaga
     9601 acgccggcac gttgcggatg gtcaccgagc gggcggcgcc gttcaccacc tcgacgtcgg
     9661 cggtgaccag gccggccggc acgtcgagcc ggatggtggt gaccggctcg gtgacctcca
     9721 ccatgccggt ctccaccagc acggtggcca ccccgatggt gccgtggccg cacatcggca
     9781 gcagtcccga gacctcgatg aacagcacgc cgacgtccgc gtcggggcgc gtgggcggct
     9841 ggaggatggc gccgctcatc gcggcgtgcc cgcgcggctc gtacatcagc agcgtgcgca
     9901 cgtcgtcgct gttgtcgatg aaccactgcc gccgttcggc catggtgctg cccgggatgg
     9961 tcccgacgcc accggtgatg acgcgggtgg gcatgccctc ggtgtggctc tcgaccgagt
    10021 ggaaaacgcg tttcgatcgc atgtcctgtc cttcagcgtg ccgtgtgcgt tcgtgccgtg
    10081 tgcgtgccgc gtgcgtcttc gcgccgcggc cccccgtgcg ggcgtcccgg tgtgccatgg
    10141 tgcccgacgg cgccgccggg ccggcgccgt cgcccgcccc ggcggcgcgg ccggatcagc
    10201 ggtggcccgc ggcgagcacg gcctcggtgg tggcgcgcac ggcggcctcg gcctcgggga
    10261 ccagcggcga gcgcggcggc cggcaggggc cgcccttgcg gccggccacg tccatggaca
    10321 gcttgatcgc ctggacgaac tcgggcttgg agtcccagcg cagcagcggg tgcagctcgc
    10381 ggtagagcgt cagggcgcgg gagatgtcgg ccgggtcgcc cgaggtggcg agccggtaca
    10441 gctccatgct ggtgctcggc agggcgttgg ggtagccggc gatccagccg acggcaccgg
    10501 ccaggccgag ttcgagcaga acgtcgtcgg cgccgatcaa caggtcgagc tcgggggcga
    10561 gttcgcggat ctcgtacgcg cggcggacgt cgccggtgaa ctccttgacg gcgactatca
    10621 ggccctcggc gtgcagttcg gccaggagcg cgggggtgag gtcgacgcgg gtgtcgaagg
    10681 ggttgttgta ggcgacgacg ggcaggccgg ccttggcggc ctcgcggtag tgggccagga
    10741 ccgtgcgctc gtcggcgcgg taggcgttgg gcgggagcag cagcaccgag tgggcgccgg
    10801 cctcggcggc ctgctcgatc cagcggcggg actggagcac gccgtaggcg gcgacgcccg
    10861 gcatcaccgt gaagccctcg ggcgccgcgg cgacggcggt ctcgaccacg cgggcgcgtt
    10921 cggcgtcgct gaggctctgg tactcgccga gggagccgtt cgggcacacg ccgtcgcagc
    10981 cttgctcggc cagccacgcg acgtgctcgg cgaagccgtc gaagtcggcc gcgaggtcgt
    11041 cgtcgaaggg gaacgcggtg gcgacgtgga cgccgcgcca gggctgccgt gcagcggtca
    11101 tggtgatctc ctcgtaggtg gggccgctct aggactacca ataaaatgtc acattgcata
    11161 gtccggcggc gcacattcgc ggtccggatg aacgggccgc aaaatcctcc cctcgcaccc
    11221 attgcccgcc cctgcggcat gtgacatgtt actgagccac atattcgagc cacggggagg
    11281 atggaatgag acagacgccg gggaaagtcc tcgccgtcgt cgccggtgtg gtcgttctgg
    11341 ccccggggtg cgcccccgac accagcacgg cggagggcga gtaccgcgtc gccgtgctcg
    11401 ccgcctcggc gcagaacggc tacaaccagg ccgtgtacga cggcgtcgtg gccggcgcgg
    11461 aggaactcgg cctcaccgtg gacgtcaaga tcctcgacgg cggcttcgac tccaccacgc
    11521 agctctccca gctccagacg gcggccaccg tgggcggcta cgacggcgtc atcgtcgttc
    11581 cgcacgacgg gcccagcctc gccggggcgt tccccctcgc gaactccgtc ccggtgatca
    11641 ccgtcctcaa ccccatcggc cccgacgtcg acgacatgga gccgcaggtc gagggcgtgg
    11701 tctccaccgt ggccgtgccg ccgagcgacg cggctgcccg gcaggcggag ggcgtggtgg
    11761 accactgcgc cgacctcgac ccctgcaagg tcaccctcgt cgtgggcgac ctctcctccc
    11821 cgctcgacat cgcccgccgc gacgcctacc ggggcgtgct cggcgagcac gcgaacatcg
    11881 aggtcgtcag caccgtcgag ggcaactacg accgctacca gtccctgacc gcggtctcca
    11941 acagcctcca gtccaaccgc gacgtcgacg tcatcctcgc cagcgccgac cagatgacgc
    12001 tgggcgcgga gctggccctg gagaacgcgg gcatcgcgcc cgagagcgtg tacctgaccg
    12061 gcggaggcgg caccaccgag gcggtccgag ccgtccgcga ggggcgctgg acggccaact
    12121 acctcaactt ccccgtgagc atgggcgccg ccgccatgga gcagctcgcg aacgccatga
    12181 ccggccggcc ggtcgagacc gtcgtgaacg ccgacaccgt cggccccgag ggcgtcgaac
    12241 cctacgccac ccgggagacg ctggccggcc cggaggccga ggacttcacg ggggagtgga
    12301 acggctgatg acgacgacga ccgaaacgtc cagcaccgcg aacgccgggc cggcccccgt
    12361 gctcaccgcc cgcgacctgt ccaagtggtt cggcggcacg cacgccgtgg acggggtgag
    12421 cctcgacctg ctgcccggcg aggtgcacgc gctggtgggg gagaacggcg ccggcaagtc
    12481 caccctgggc aagctgatcg ccggggtcta ccagcgggac gggggcgacc tcgtggtgga
    12541 cggcgccgcg atcggccgct gggacccggc acgggccggt cgccacggca tcgccatgat
    12601 cgcgcaggaa ctggccctcg tccccgagct gaccgtggcg cagaacgtct tcctcggccg
    12661 cgagcgttcc cgggccggcg tcctgcggcc gggcaccgcg gcggagttcg aacggatcga
    12721 cgcgatggcg cgcttcggcc tgccgcccca ccgcaaggtc cgcgacctgg gcatcgccga
    12781 ccagcagaag gtcgagatca tgcggtccct ggccagggac gccaaggtcg tcgtgatgga
    12841 cgagcccacc tcgtccctca ccgcccacga gacggagaag ctgcacgagc tgatccgcac
    12901 cctgcgcgcc cagggcagaa ccgtcgtcta cgtctcccac ttcctcgacg cggtcctcgg
    12961 gatcgcggac cgggtgacga tcatgcggga cggccgcctg gtgcgcaccg gccccgcggc
    13021 ccgggagacg aaggcgagcc tgatcgaggg catgctcggc cgctccctcg cggtcacctt
    13081 tcccgagcgg agcgcgcccg ttccccccgc gacgcccccg gtgctcgacg cgaagggcct
    13141 ggcgaccgcc gagggcgtcg tggacgcctc gctgaccgtg cgccccgg
//
