LOCUS       NZ_CP084541            21065 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces marincola strain SCSIO 64649 chromosome, complete
            genome.
ACCESSION   NZ_CP084541
VERSION     NZ_CP084541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Strepomyces indimicinicus sp. nov., an antibiotic producing
            actinomycetes isolated from the marine environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Sciences, 164 Xingang West Road, guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. V6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 444.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020410765.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,763
            CDSs (total)                      :: 5,689
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 74
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 21 of 77
            Pseudo Genes (incomplete)         :: 60 of 77
            Pseudo Genes (internal stop)      :: 2 of 77
            Pseudo Genes (multiple problems)  :: 6 of 77
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:57:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3790119
            Orig. end                         :: 3811184
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21065
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="23"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21065
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21065
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11065](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11065)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(37..1431)
                     /locus_tag="LC193_RS16500"
                     /old_locus_tag="LC193_16500"
     CDS             complement(37..1431)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009294477.1"
                     /locus_tag="LC193_RS16500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16500"
                     /product="hypothetical protein"
                     /protein_id="WP_226075061.1"
                     /transl_table=11
                     /translation="MDFLDVYHLWADAHAFFDSTLIPDPSDHTDPLAAQAAGWDRRLAE
                     DTPNGHLLRRNALFEALSGNGKLHLLHVTHALEKISRQGVLYPSGGCLVGSIYCAPLTA
                     TDQGFHMHNLGSYVLTKEAPTFLAKLGVTDRVPTPLIFEIDTPRQAYRGLAGVDYLRLG
                     LIHLNIYSHLEYLLSKNERHQLRETVVSRIKNSAAFLATAAAVAYQGTQVDAEPFLKLL
                     DETIPRLPILGYLYFEAVAEYLMLHSTSHHTRRLAELGELNNWLYKEMLFASFPAMAGK
                     FDLARFRPRPKQLAALIHRVDPTIDTTHASAYLVERISYLVAARLFAPGDTPEAWHHTR
                     WEFDSLATQLGPLLGHLIHRELRTFGRYPDFYFYFDQHKALQAWNYWNHMDIVAPFNGT
                     MPKGEIGINPAYPNLDYRVWRAEQDDAGHLHPAEQLSLTIAPRLVDIKYTLMRNNQWTP
                     PAPSVA"
     gene            complement(1434..2198)
                     /locus_tag="LC193_RS16505"
                     /old_locus_tag="LC193_16505"
     CDS             complement(1434..2198)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955014.1"
                     /locus_tag="LC193_RS16505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16505"
                     /product="hypothetical protein"
                     /protein_id="WP_226075063.1"
                     /transl_table=11
                     /translation="MSTTPLTASLIALAARGQLPLHQHMDHATIAWISDNRPDLPPAPQ
                     PALRPQSKELLAHGGLPTRWWADPRLYTSLHGVRHAMRTAALAAILADTNGLDDADAAT
                     AILAAAVHDCQRRHDQDDRGHGARAAIWLAANADTLWGHFGLAAAPRRIMQATTAVRLH
                     DIPYEAFTPDDKSDHARAERITDVVKAADALDRYRLPKLTWWPDSRYVREPAFNQLRGL
                     AFDLVLVSERAYLAGASGTAAVRYALAEKGLV"
     gene            complement(2238..2822)
                     /locus_tag="LC193_RS16510"
                     /old_locus_tag="LC193_16510"
     CDS             complement(2238..2822)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500624.1"
                     /locus_tag="LC193_RS16510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16510"
                     /product="hypothetical protein"
                     /protein_id="WP_226075064.1"
                     /transl_table=11
                     /translation="MAVEVEMRARFTKEVHDQLVTRLKADGEDLGPDDKHIYFYVLPDQ
                     LLKVTDNTVAGTAKITLKGSKIGQGAAFAETEFAIASADVPAAVKVFNALGFETTMHEA
                     FNFRHNFRLDDVEIAVKWSEAWGYHAEFEVLLEDGASDAARAEAEAKITDVATALGVTL
                     MTEQELADFTAAFEAAEQERKEREQQAAPIR"
     misc_feature    2957..2971
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(2981..3280)
                     /locus_tag="LC193_RS16515"
                     /old_locus_tag="LC193_16515"
     CDS             complement(2981..3280)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003955012.1"
                     /locus_tag="LC193_RS16515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16515"
                     /product="hypothetical protein"
                     /protein_id="WP_226075065.1"
                     /transl_table=11
                     /translation="MTNQTRLASTDELESIFQRELATDRWAAAETAYALAVRHRDAGDW
                     PASQEWAQQCLRLLEGFPSETEEQVATGRTSVGGVQLPTYLHSGVVEKRFGTLG"
     misc_feature    complement(3358..3371)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.74"
                     /tool="antismash"
     misc_feature    complement(3359..3374)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.15"
                     /tool="antismash"
     gene            complement(3360..3869)
                     /locus_tag="LC193_RS16520"
                     /old_locus_tag="LC193_16520"
     CDS             complement(3360..3869)
                     /EC_number="2.7.4.6"
                     /GO_function="GO:0004550 - nucleoside diphosphate kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006165 - obsolete nucleoside diphosphate
                     phosphorylation [Evidence IEA]"
                     /GO_process="GO:0006183 - GTP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006228 - UTP biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006241 - CTP biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605560.1"
                     /locus_tag="LC193_RS16520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16520"
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_226075066.1"
                     /transl_table=11
                     /translation="MAEVQAHTVERTLVLLKPDALARGLAGRIITRFEDAALKIVGTKM
                     KWMDEEFTRKHYFDLEERLGSEVYSVTATFMQQGPVIALVLEGFDAIATVRKIVGSTYP
                     NQAPAGTVRGDFSHYSAAASTASGKAVANLVHASGNAEEAKQEVELWFDKDELQDYKTL
                     AEIYTY"
     misc_feature    3884..3897
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.45"
                     /tool="antismash"
     misc_feature    3885..3898
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.1"
                     /tool="antismash"
     misc_feature    3886..3899
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.43"
                     /tool="antismash"
     misc_feature    complement(3891..3900)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     misc_feature    complement(4193..4208)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            4276..4935
                     /locus_tag="LC193_RS16525"
                     /old_locus_tag="LC193_16525"
     CDS             4276..4935
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088332.1"
                     /locus_tag="LC193_RS16525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16525"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_226075067.1"
                     /transl_table=11
                     /translation="MDVIERWSGRYACLLQSALRLGNEQFAAHLGIAVRTVATWHSDAS
                     VVPRREMQQLLDTAHEQAPPAARQRFALLLAKERSPVDSMPPGAQALRVAIAVVVRGTD
                     VLLVCRRDDDAAGITWQFPAGVIKPGGKAETTTVRETLDETGVHCAVRQHLGNRLHPVT
                     GVLCEYFLCEYLAGEATNSDAAENIDVMWVPRNSVLRFISVDTIFSPILAVLEEQT"
     gene            4932..5345
                     /locus_tag="LC193_RS16530"
                     /old_locus_tag="LC193_16530"
     CDS             4932..5345
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500628.1"
                     /locus_tag="LC193_RS16530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16530"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_226075068.1"
                     /transl_table=11
                     /translation="MTNQNTDERPGIAAAIVVNKARVLMVRRRVSEGQLSWQFPAGEVE
                     PGEAREDAAVRETQEETGLTVAAVKLLGERVHPKTGRLMSYTACEVLGGSAHVADTEEL
                     AELAWVAHGEIPEYVPFGLFEPVQEYLDTVLSS"
     gene            5367..6119
                     /locus_tag="LC193_RS16535"
                     /old_locus_tag="LC193_16535"
     CDS             5367..6119
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100247.1"
                     /locus_tag="LC193_RS16535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16535"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_226075069.1"
                     /transl_table=11
                     /translation="MATDVLLAGARERWETWARAPVSFPGAGGVCVVASPDSGLSPPGW
                     VGLVALGGSAIVTAPRPDTAAVVRAAVGSLPGDAVTDAEAVRAVLPVTDVLGPAALAYA
                     SADGFRPVAADEANVRRLPQGAAGSGALDDLVDQVTDEEAAEAGIVGITSPAFVVRSGG
                     RVVAAAGYEVWPDRVAHVCVLTGARWRGRGLARAVGSAAVAHAFAAGLLPQWRARGPAS
                     RRVAAALGFRKLGAQLSIQLAADAGMVR"
     gene            complement(6253..6480)
                     /locus_tag="LC193_RS16540"
                     /old_locus_tag="LC193_16540"
     CDS             complement(6253..6480)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS16540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_16540"
                     /product="hypothetical protein"
                     /protein_id="WP_226075071.1"
                     /transl_table=11
                     /translation="MKGVLVSVEIDARTVAIGDQVMVGGQALTVHDMTAMSQGRKRLVF
                     ATGESFVMGRATVLWASRRVDPRIGRGRRW"
     gene            complement(6477..6632)
                     /locus_tag="LC193_RS16545"
                     /old_locus_tag="LC193_16545"
     CDS             complement(6477..6632)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS16545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_16545"
                     /product="hypothetical protein"
                     /protein_id="WP_159029815.1"
                     /transl_table=11
                     /translation="MSPFFCDHFCELTRRDDGAHCASCDALIYPADVLPPRSAEQEPVP
                     TVEADQ"
     misc_feature    complement(6929..6939)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: strong, score: 22.4"
                     /tool="antismash"
     gene            6964..7845
                     /locus_tag="LC193_RS16550"
                     /old_locus_tag="LC193_16550"
     CDS             6964..7845
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008747446.1"
                     /locus_tag="LC193_RS16550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16550"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_226075073.1"
                     /transl_table=11
                     /translation="MAETTGSTVPRRQLGRHLRELRNQAGYTIKGAAKAVEMSDTKIWR
                     IETGQTSLRSFDVEIMCRIYGAPADLTEALMGLAKETKARGWWHSFGEAIPEGFDLYIG
                     LEEASARIDWYEPLLIPGLLQTEEYAHAVMRAYNPEESDEEVERRVRLRMSRQHLLTRY
                     VSPPHLRMVVEEGVFRRPVGGAAAMAKQLRQVVELADLPTVDLRVAHFGSGLHLGMLSG
                     QFTILRFPVNGDGKNSEPTTVYSDGFTGNLYLDKPREVDRYDAVFSDMWDGALDEVASR
                     RLILGVAGEYEQ"
     gene            7835..8038
                     /locus_tag="LC193_RS16555"
                     /old_locus_tag="LC193_16555"
     CDS             7835..8038
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018105650.1"
                     /locus_tag="LC193_RS16555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16555"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_226075076.1"
                     /transl_table=11
                     /translation="MSSNAGPGWVKSSYSSNGNQCVEVNVGSATVVGVRDTKQEGAGPE
                     LWVPAASAAAFVAGVVNGTLSA"
     gene            8186..8683
                     /locus_tag="LC193_RS16560"
                     /old_locus_tag="LC193_16560"
     CDS             8186..8683
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005312515.1"
                     /locus_tag="LC193_RS16560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16560"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_404819425.1"
                     /transl_table=11
                     /translation="MDQQTDDQPKAARPALASMTLLVAAVIVHDRATDRVVLLQRGENA
                     TFAPGKWDLPVGKSEPGEPITETAVRELFEETGLTVRPEDLKAAHIIHKAWGVEAPNGF
                     LTVVFAAHAWTGEPENREPRKHSRVCWVDTDAIPENFVDTTSSALHGYIAGDTDISLGG
                     WR"
     gene            complement(8707..8907)
                     /locus_tag="LC193_RS16565"
                     /old_locus_tag="LC193_16565"
     CDS             complement(8707..8907)
                     /GO_component="GO:0032993 - protein-DNA complex [Evidence
                     IEA]"
                     /GO_process="GO:0006276 - plasmid maintenance [Evidence
                     IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134614.1"
                     /locus_tag="LC193_RS16565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16565"
                     /product="CopG family transcriptional regulator"
                     /protein_id="WP_404819426.1"
                     /transl_table=11
                     /translation="MPMKRTTVYADPEDLAIIKEAARRRGISEAEIIRQGIHLVAMANR
                     VWDEPLFSRTFEGSGRTRSCS"
     gene            complement(9027..10004)
                     /locus_tag="LC193_RS16570"
                     /old_locus_tag="LC193_16570"
     CDS             complement(9027..10004)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007496674.1"
                     /locus_tag="LC193_RS16570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16570"
                     /product="DUF5914 domain-containing protein"
                     /protein_id="WP_226075078.1"
                     /transl_table=11
                     /translation="MTARTRYPLRLGRRTAWEAQRPTWRDARPALIAEALAHALAQPTG
                     NWYVLGASTDVARGRPFGRTIGGTEVVAWRDRAGRLLAGQGACPHLGAPLAESRVRCGR
                     LVCHWHGLALDGRPFAGWQPFPAHDDGVLAWVRLDELGGEEPSTVPHVPQRPEAARALD
                     AVFTGTGRCEPQDVVANRLDPWHGAWFHPYSFVDLTVVAVAPERLTVDVSFRVAGRAVV
                     PVRAVFTAPGPRTVTMLIAEGEGRGSVVETHATPLGPGPDGAPRTAVIEAVVATSHRPG
                     FALARAAAPLARPLMRAAAGRLWRDDMAYAERRHTLRARNTFPG"
     gene            complement(10001..11065)
                     /locus_tag="LC193_RS16575"
                     /old_locus_tag="LC193_16575"
     CDS             complement(10001..11065)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134618.1"
                     /locus_tag="LC193_RS16575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16575"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_226075080.1"
                     /sec_met_domain="phytoene_synt (E-value: 2.7e-112,
                     bitscore: 372.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.1e-62,
                     bitscore: 208.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARELDAARITNPALRAAYTHCRRLNARHGRTYFLATRLLPADR
                     RPAVHALYGFARWADDIVDDLAPGTPAEERARALDALAARVAAVFERPAVPGPSASPGT
                     SASAGAFDGARGPDTAHAPVVRALAHTVARYRIDPDYFTAFLRSMRSDLVVTDYPTYQD
                     LRGYMYGSAAVIGLQMLPVLGTVVPRAEAAPHAAALGEAFQLTNFLRDVGEDLDRGRIY
                     LPGDLLAAHGVDRDLLCWSRRTGRRDRRVTAALMAAAALTRGVYRAAEPGVAMLDPVAR
                     PCIRAARTLYSGILDAVAADGWSVLHRRAVVPRHRRAAVALDGLARAVAARRRARPGGH
                     TPALVAAATERSPA"
     gene            complement(11062..12585)
                     /gene="crtI"
                     /locus_tag="LC193_RS16580"
                     /old_locus_tag="LC193_16580"
     CDS             complement(11062..12585)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946705.1"
                     /locus_tag="LC193_RS16580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16580"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_226075082.1"
                     /sec_met_domain="DAO (E-value: 2.5e-16, bitscore: 58.6,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRLTGPTGRVVVVGAGLSGLSAALHLLGAGREVTVVERAALPGG
                     RAGRVDLGGYLLDTGPTVVTMPELIDEAFAAVGTSLRERLDLVPLHPAYRARFADGGHL
                     DVHTDAAAMEAEVRRCAGPREAAGYRGLRQWLEALYRAQLHRFIDANFDSPLRLLNPDL
                     ARLAALGGFGRLDRQVGRFLSDERLRRVFTFQSLYAGVSPTRALAAYAVIAYMDTVSGV
                     YFPRGGVHALPRALAAAATDAGGTFHWGQTVTRLERRGDRVTAVHTADGLRLPCDAVVL
                     TPELPTAYRLLGRVPRRPLRLRHAPSAVVLHAGTTRTWPGLGHHTLSFGRAWERTFEEL
                     TRSGRLMTDPSLLITRPTAHDPSLAPPGRHLHYVLAPCPNTAIGPDADAWRTLGPRYRD
                     RLLAELERRGLAGLAAAIEAEHLVTPADWARQEHAAGTPFSAAHTFAQTGPFRPRNLVR
                     GTSNAVLAGCGTTPGVGVPPVLLSGKLAAARVTGLRGGDRSRTTITLAS"
     misc_feature    complement(12556..12570)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 24.85"
                     /tool="antismash"
     gene            complement(12877..14037)
                     /gene="nrfD"
                     /locus_tag="LC193_RS16585"
                     /old_locus_tag="LC193_16585"
     CDS             complement(12877..14037)
                     /codon_start=1
                     /gene="nrfD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014628693.1"
                     /locus_tag="LC193_RS16585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16585"
                     /product="NrfD/PsrC family molybdoenzyme membrane anchor
                     subunit"
                     /protein_id="WP_226075083.1"
                     /transl_table=11
                     /translation="MSDAEVTRAGLRNERPGSHALFGNGMPGGPGAVPDGAPPDGQRPY
                     GADAFSTGTGSGERRAAGPAGRRRSRGGPGGGPGDGEAFTSYYGRPVLKAPHWAATDIA
                     GYLFLGGLAGAGSVLAAGAELTGRRATARAMKLSSLGAVSLSVVALVHDLGRPARFLNM
                     LRVIKPTSPMSIGSWLLAGYGPLAGVAAVTDTTGLFPRTGRAATCGAAVFGPAVAAYTG
                     VLFADTAVPAWHEGHRELPYLFTGSAAAAAAGMALLAAPGRESGPARRAAVLGTAAEFA
                     AMRALHRRAGPVDETYRRGKAGRLLRAASVLGAAGAAGAAGLAGRSRAAAALSGAALLA
                     ASACTRFGLFHAGLASVRDPKYTVEPQRARLAAAEAHAAAEAAETP"
     gene            complement(14034..14930)
                     /locus_tag="LC193_RS16590"
                     /old_locus_tag="LC193_16590"
     CDS             complement(14034..14930)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146156.1"
                     /locus_tag="LC193_RS16590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16590"
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="WP_226075084.1"
                     /transl_table=11
                     /translation="MTTEPPDLTTQRPNLTTERPNLLYGPEPDVAADAGHTDPPERVGF
                     FTDTSVCIGCKACEVACKEWNAVPEDGLDLTGMSYDNTGALGASTWRHVAFIEQAKPLG
                     GQQSQPDMRWLMASDVCKHCTHAACLDVCPTGSLLRTEFGTVVVQEDICNGCGYCVPAC
                     PYGVIEQREGDGRAWKCTLCYDRLGAGSEPACAKACPTDSIQFGPLETLRERAAERVAQ
                     LHATGVPDARLYGEDPADGVGGAGAFFLLLDEPEVYGLPPDPQVTTRDLPAMWRHAGVA
                     AAALLTGLAAMFAGGRR"
     gene            complement(14934..18191)
                     /gene="fdh"
                     /locus_tag="LC193_RS16595"
                     /old_locus_tag="LC193_16595"
     CDS             complement(14934..18191)
                     /EC_number="1.17.-.-"
                     /codon_start=1
                     /gene="fdh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134: flavodoxin"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227547.1"
                     /locus_tag="LC193_RS16595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16595"
                     /product="formate dehydrogenase"
                     /protein_id="WP_226075085.1"
                     /transl_table=11
                     /translation="MGVRTWIQDWPVYRQLTGTDPLGRGAAARSARTARLRPRTDTADR
                     VVDSICPYCAVGCGQQIYVKDERIVQIEGDPASPVSRGRLCPKGSATLQLVTGDARRHQ
                     VLYRRPHGTAWEPIGLDEAMDMVADRVIKTRRETWQWEVEGSRVARTLGIASLGGAVLD
                     NEENYLLKKLFTGLGIIQIENQARVCHSSTVAGLGTSFGRGGATTFMQDLQNADCIVIQ
                     GSNYAEAHPVGFQWVMEAKARGATIVHVDPRFTRTSALADLHVGIRAGSDIAFLGGIIN
                     HVLSEGKEFRDYVLAYTNAATIVSEDFRDTEDLAGVFSGLDEEGRHYDPESWQYEGAAV
                     RSLAGEPDPHRNLRLDDAAIEHAAGGSESHGSGGQDVTPRPRRDETLTHPRCVFQILKR
                     HYARYTPEMVERVCGVSPERFAQVCDILTRNSGPERTGAFVYAVGWTQHTVGSQYIRAA
                     SVLQLLLGNIGRPGGGIQALRGHASIQGSSDIPTLFNLLPGYLPMPHAQAHQDLDSFVR
                     AVRARKGYWADMNAYMVSLLKAYYGDAATAENDFCFDHLPRLTGSHSTYDTVMAQLDGV
                     CKGYFLLGENPAVGSANARLQRLGMARLDWLVVRDFSLIESATWWLDGPEIETGELRTE
                     DIGTEVFFFPAASHAEKSGSFTNTNRWLQWHHAAVEPAGDARSELWFAHHLHRRIREKL
                     AGSDDPADRLFLDLAWDYPVTGAHDEPIADAVLAEINGRGPDGAPLSAYTELRDDGSTS
                     CGCWIYCGVYADGVNRAARRKPHTEQDWVAAEWAWAWPANRRVLYNRASAAPDGTPWSE
                     RKAYVWWDADAGRWTGHDEPDFPLTCPPDHVPDENAFGVAALRGDDAFIMQGDGKGWLY
                     APAGLVDGPMPTHYEPQDSPFGNALHPHHPRSPVRLAFPREGNEYHPANGAPGSHVYPY
                     VVTTYRLTEHFTAGGMTRWSPYLAELQPELFCEVSPELAAERGLAHAGWATIITARSAI
                     EARVLVTERMAPLRADGRTVHHIGLPYHWGPNGYSTGDAANELSAIVLDPNVHIQEVKA
                     LTADIRPGRRPRGPALRALVEDYRRRAGADERTGLEV"
     gene            18513..18842
                     /locus_tag="LC193_RS16600"
                     /old_locus_tag="LC193_16600"
     CDS             18513..18842
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS16600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_16600"
                     /product="hypothetical protein"
                     /protein_id="WP_226075086.1"
                     /transl_table=11
                     /translation="MADIEWAVQECRECGHPRADHDPLVRVEGRCRGTTAVPAGGRAPR
                     PCACREFWPKPQDVGGPGTWPCASCGHRRHLPAACRARAVGGGDGLRNCRCGYEPPRPW
                     LDPIG"
     gene            complement(18903..19346)
                     /locus_tag="LC193_RS16605"
                     /old_locus_tag="LC193_16605"
     CDS             complement(18903..19346)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS16605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_16605"
                     /product="hypothetical protein"
                     /protein_id="WP_226075087.1"
                     /transl_table=11
                     /translation="MSTPGGGDQHPEAIERLLAAALRARAETVTADDLRAPRPPSAHAP
                     RRLRVLSGRATAAALLGLAAAVVAALLALGGRAPEPPPTRPAGVPSDLPLPHQEATPAP
                     VPAPSPQPLDPREFPSDGGEDAGSHPNVPVEAVEPVRPDDGMP"
     gene            complement(19343..19945)
                     /locus_tag="LC193_RS16610"
                     /old_locus_tag="LC193_16610"
     CDS             complement(19343..19945)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565382.1"
                     /locus_tag="LC193_RS16610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16610"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_226075088.1"
                     /transl_table=11
                     /translation="MTGLPVVRGGTGRRGTRPAPEPSGGPPPSPPGGGAGDARRPDIDD
                     LYHHSRLDLVRLALFLVDDVPTAEDVVQDAFAALLRRHGPELDAVDAPEAYLRTSVVNA
                     ARSVLRRRRTVRAHVPERPGHGPSADEYVLLREEHRTVLHALRRLTRRQREVLVLRYWS
                     GLSEIQIADTLGLSPGTVKSTASRALTALRRHLETSP"
     gene            complement(20053..20472)
                     /locus_tag="LC193_RS16615"
                     /old_locus_tag="LC193_16615"
     CDS             complement(20053..20472)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949098.1"
                     /locus_tag="LC193_RS16615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_16615"
                     /product="hypothetical protein"
                     /protein_id="WP_226078922.1"
                     /transl_table=11
                     /translation="MPTPQAGPPRSGARRLRVALVTAAAGLAVTVGGVLTAHATNASPA
                     SSGAEPAPVPAEEAPAEEAPAEEAPAPVPAPDEAGPEDSGAEPVPVPAEEAPAEEPVPV
                     PAEDCPEESGAEPAPVPVPREAPPVDEDPPARSGR"
     misc_feature    complement(20601..20616)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
ORIGIN
        1 gctcggggtg gggtgtgccg cggatagccg cgatggtcag gcgacgctgg gcgcgggagg
       61 ggtccactgg ttgttgcgca tgagggtgta cttgatgtcc accagccgcg gggcgatggt
      121 cagcgaaagc tgttcggccg ggtggaggtg gccggcatcg tcctgctcgg cgcgccagac
      181 gcggtagtcg aggttggggt aggccgggtt gatgccgatc tcgcccttgg gcatcgtgcc
      241 gttgaacggt gcgacgatgt ccatgtggtt ccagtagttc caagcttgca gcgccttgtg
      301 ctggtcgaag tagaagtaga agtcggggta gcggccgaag gtgcgcagtt cccggtggat
      361 gaggtggccg aggagcggtc cgagctgcgt ggccagggag tcgaactccc agcgcgtgtg
      421 gtgccaggct tccggggtgt cgccgggcgc gaagaggcgg gcggcgacga ggtagctgat
      481 ccgctcgacc aggtacgcgc tcgcgtgggt ggtgtcgatg gtcgggtcga ctcggtggat
      541 gagcgcggcc agctgcttcg gacggggacg gaacctcgcg aggtcgaact tgccggccat
      601 ggcggggaag gaggcgaaca gcatctcctt gtacagccag ttgttcagct cgccgagctc
      661 ggccaggcgc cgggtgtggt gcgaagtcga gtggagcatc aggtactcgg cgaccgcttc
      721 gaagtacagg tagccgagga tcggcagtcg ggggatcgtc tcgtcgagca gcttgaggaa
      781 cggctcggcg tcgacctggg tgccctggta ggcgacagcg gcagcggtgg cgaggaatgc
      841 ggccgagttc ttgatccggc tgacgacggt ctcgcgtagc tggtgccgtt cgttcttgct
      901 cagcaggtat tcgaggtggc tgtagatgtt caggtggatg aggccgaggc gcaggtagtc
      961 cacgccggcg agacctcgat acgcctgccg cggggtgtcg atctcgaaga tgagcggggt
     1021 ggggactcga tcggtgacgc cgagcttggc caggaaggtc ggcgcttcct tggtcaggac
     1081 gtaggagccg aggttgtgca tgtggaagcc ctggtcggtc gcggtgagcg gcgcgcagta
     1141 gatgcttccg acgaggcagc cgcccgacgg gtaaagcact ccctgccggc tgatcttctc
     1201 cagggcgtgg gtgacgtgca gcaggtgcag tttgccgttt ccgctcaggg cctcgaagag
     1261 ggcgttccgc cgcagcaggt ggccgttcgg ggtgtcctcg gcgagacgcc ggtcccagcc
     1321 cgccgcctgg gcggcgagcg ggtcggtgtg gtcggagggg tcggggatga gagtggagtc
     1381 gaagaaggca tgggcgtcag cccacaggtg gtagacgtcg aggaagtcca tggtcagacc
     1441 aggcccttct cggcgagcgc atagcggacg gccgcggtgc cgctggcccc ggcgaggtag
     1501 gcccgctccg agaccagaac caggtcgaag gcgaggccgc gcagctggtt gaaggcgggc
     1561 tcgcggacgt accgggaatc cggccaccac gtcagtttcg gcaggcggta gcggtccagg
     1621 gcgtcggcgg ccttgaccac gtcggtgatg cgctcggcgc gggcatggtc ggacttgtcg
     1681 tctggggtga acgcctcgta cggaatgtcg tgcagccgga cggcggtggt cgcctgcatg
     1741 atgcgtcggg gtgcggcggc gaggccgaag tggccccaga gggtgtcggc gttcgcggcg
     1801 agccagatgg ccgcgcgggc gccatgcccg cggtcgtcct ggtcgtggcg ccgctggcag
     1861 tcgtgtacgg cggcggcgag gatcgccgtg gcggcgtcgg catcgtcgag gccgttcgtg
     1921 tcggcgagga tggcggcgag cgccgccgtc cgcatggcgt ggcggacgcc gtggagcgac
     1981 gtgtacaggc gggggtcggc ccaccaccgg gtgggcagtc cgccgtgcgc gagtagctcc
     2041 ttcgactgcg ggcgcaaggc cggctgcggt gccggtggga ggtcgggcct gttgtcgctg
     2101 atccacgcga tggtggcgtg gtccatgtgc tggtggagcg ggagctgccc tcgggcagcc
     2161 agggcgatca gacttgcggt caacggggtc gtgctcactc gtgcccaccc ccttggtggt
     2221 ctccgcggtg atgttctcta ccggatcggc gcggcctgct gctcgcgctc cttgcgctcc
     2281 tgctcggcgg cctcgaaggc tgcggtgaag tcggccagct cctgctccgt catcagggtc
     2341 acgccgagcg ccgtggcgac gtccgtgatc ttggcctcgg cctcggcgcg ggcggcgtcg
     2401 gaggcgccgt cctccagcag gacctcgaac tcggcgtggt agccccacgc ctcactccac
     2461 ttgaccgcga tctcgacgtc gtcgagacgg aagttgtgac ggaagttgaa cgcctcgtgc
     2521 atcgtcgtct cgaacccgag ggcgttgaac accttcaccg cggcgggaac gtcggcggag
     2581 gcgatggcga actcggtctc cgcgaaggcc gcgccctgcc cgatcttgct ccccttgagg
     2641 gtgatcttgg cggtgccggc gacggtgttg tcggtgacct tcaagagttg gtcggggagt
     2701 acgtagaagt agatgtgctt gtcgtcgggg cccaggtcct ccccgtccgc cttcaggcgg
     2761 gtgacgagct ggtcgtggac ctccttggtg aagcgggcgc gcatttcgac ctcgacggcc
     2821 acggggctgc tgcctcctcg tttcaggcat ggcgaagcca gccggaccct gccgtgcggg
     2881 ggctgtccgg tcgggcgatc gctatgggct tggtggttga gcgcggggtg atgcggccga
     2941 tgcgggtgct ggccgcatca ccccggtgga tcggtgggtg tcagccgagg gtgccgaagc
     3001 gcttctcgac cacacccgag tgcaggtagg tcggcagctg gacgcctccc accgacgtgc
     3061 ggccggtggc gacctgctcc tccgtctcgc tggggaagcc ctccagcaga cgcaggcact
     3121 gctgggccca ttcctgcgac gcgggccagt cgcccgcatc gcggtggcgc acggccaggg
     3181 cgtacgcggt ctcggcggca gcccaccggt cggtcgccag ctcacgctgg aagatcgact
     3241 ccagctcgtc ggtggaagcc aggcgggtct ggttggtcat ggtgacctct cggttcaacg
     3301 gtcgtgcccc agtggtgatc aacgccccgg cgtccccacc gtcacgccgt gccccgctgc
     3361 taatacgtgt agatctcggc cagcgtcttg tagtcctgta gctcgtcctt gtcgaaccac
     3421 agctcaacct cctgcttggc ctcctccgcg ttgccggacg cgtgcacgag gttcgcgacc
     3481 gccttgcccg atgcggtgct ggccgccgcg ctgtagtgcg agaagtcgcc ccgcaccgtg
     3541 ccggccggag cctggttcgg gtatgtgctg ccgacgatct tgcggaccgt agcgatggcg
     3601 tcgaagccct ccagcaccag agcgatgacc ggcccctgct gcatgaacgt cgccgtgacg
     3661 ctgtagacct ccgaccccag ccgctcttcc agatcgaagt agtgcttgcg ggtgaactcc
     3721 tcgtccatcc acttcatctt cgtgccgacg atcttcagcg cggcgtcctc gaatcgagtg
     3781 atgatccttc ctgccaggcc acgcgccagc gcatcgggct tgagcaggac gagcgtacgc
     3841 tcgacagtgt gtgcctgaac ctcggccatt gactcccttt cgccttgctt acaaaaaaca
     3901 tgacggacac ccagccgtca gctgctgagg ttaccggcgc tggcagggcg gttcgggcgc
     3961 gcgggcaatg ccccggacgg gcgaatgctg gccaaggtgc ggccgatcag accgtcgaga
     4021 gactcgatcc ggccaacttc tctgtctccg ctatccgctg ggggcgggca tctagaatct
     4081 ccctgtggtc gttcggcgct ctcgcgcctc ttatgcgcct cccagggact gagcctttgg
     4141 cgggtgattc cttggcccct ggtgactccg attcttccgg ggcccttccc gcgtgaccat
     4201 gaagtgccag tgcagtggga gtgcactttc agcacgcggg ttcctgcacc ggggcggcga
     4261 cgaaggggca gtcttgtgga cgtgatcgag cgctggagcg gccggtacgc ctgcctgctc
     4321 cagtccgccc tacgcctcgg aaacgaacag ttcgcggctc acctcggcat cgccgtgagg
     4381 actgtggcca cctggcactc cgacgcgtcc gtcgtgcctc gcagggagat gcagcagctc
     4441 ctcgacacgg cccatgagca ggctcctccg gctgcgcgac agcgcttcgc gctcctgctg
     4501 gcgaaggagc gatccccggt ggactcgatg ccgcccggcg cgcaggcgct gcgggtggcc
     4561 atcgcagtgg tcgtccgtgg caccgacgtc ctcctggtat gccggcggga tgacgacgcc
     4621 gctgggatca cgtggcagtt cccggctggc gtcatcaagc caggcggcaa ggcggagacc
     4681 accaccgtgc gggagacctt ggacgagacg ggtgtccact gcgcggtccg gcagcacctc
     4741 gggaaccgcc ttcaccccgt gaccggcgtg ctgtgcgaat acttcctctg cgagtacctg
     4801 gccggcgagg ccacgaacag cgacgcggcc gagaacatcg acgtcatgtg ggtccccaga
     4861 aactcggtgc tccgcttcat ttccgtcgat acgatctttt cacccattct ggccgtcctg
     4921 gaggagcaga cgtgacgaac cagaacacgg acgagcgccc gggcatcgcc gccgccatcg
     4981 tcgtgaacaa ggcacgcgtg ctgatggtgc gccgccgggt cagcgaggga cagctctcct
     5041 ggcagttccc ggcgggagag gtcgagcccg gcgaggcccg cgaggacgcc gctgtgcggg
     5101 agacccagga ggagaccggg ctgaccgtgg cggctgtgaa gctgctcggc gagcgcgtcc
     5161 acccgaagac gggccggctg atgtcataca ccgcgtgcga ggtgctgggc ggtagcgccc
     5221 acgtggcgga caccgaggag ctggccgaac tggcctgggt cgcccatggc gagatcccgg
     5281 agtacgtgcc gttcggactg ttcgagccgg tgcaggagta cctcgacacc gtcctgtctt
     5341 cctaagtggc tgccaggaat tcccgtatgg cgaccgacgt gttgctcgct ggggctcgcg
     5401 agcgctggga gacctgggca cgggcgcccg tgtcgtttcc tggcgccggg ggcgtgtgcg
     5461 tggtcgcctc tcctgactcg ggcctgagcc cgcccggctg ggtcggtctg gtggcgctcg
     5521 gcggatcagc gatcgtgacc gcgccacgcc cggacacggc cgccgtggta cgggccgctg
     5581 tgggttcgct gcccggcgac gcggtcacgg acgcggaggc ggtccgcgcg gtgctcccgg
     5641 tgaccgatgt gctcggcccg gcggcgctcg cctacgcgtc cgccgacggc ttccggccgg
     5701 tggccgccga cgaagcgaac gttcggcggc taccgcaggg cgcagccgga tcgggcgcgc
     5761 tcgacgacct ggtggaccag gtgaccgacg aggaggccgc cgaggccggc atcgtcggaa
     5821 ttacctcacc ggcgttcgtg gtcaggtccg gcggccgggt ggtcgccgcc gccgggtacg
     5881 aggtgtggcc ggaccgggtg gcccacgtct gcgtgctcac cggcgcgcga tggcgagggc
     5941 gcggactggc ccgggcggtg ggctcggcgg ccgtcgcgca cgcgttcgcg gcggggctgc
     6001 tcccgcagtg gcgggcccga ggccccgcct ctcgccgggt ggcggcggcc ctggggtttc
     6061 ggaagctggg cgcccagctc agcatccaac tcgcggcgga cgcggggatg gtgcggtaga
     6121 ccgcatggtc gttgcggccg ggcggcgagg cgggtcacgg gtctgcggcg agggcgcgaa
     6181 cgagggacag gcagaacagg cagcccgccg cgaagtgcgc ggtggccgcc gcgagcagcg
     6241 cgacggccac cgtcaccagc gccgcccccg cccaatgcgc gggtccacgc ggcggcttgc
     6301 ccacaacacg gtggcgcggc ccatgacgaa gctctcgcca gtcgcgaaca ccaaccgctt
     6361 acgcccctga ctcatcgcgg tcatgtcgtg cacggtgagc gcctggccgc ccaccatgac
     6421 ctgatcaccg atcgccaccg tcctggcgtc gatctcgacg gagacgagta cacctttcac
     6481 tggtcagcct ccacggtcgg caccggctcc tgctcggcgg agcgcggcgg aaggacatcg
     6541 gcgggataga tcaacgcgtc gcaggacgca cagtgcgccc cgtcgtcccg gcgcgtgagt
     6601 tcgcagaagt ggtcacagaa gaacggggac acgcgcactc ctcagcgggc tcggcatacg
     6661 cgaacgacga cgaggcagcg gcaccgcccc cgcgacccgc cccggcgggg gcgacgcacg
     6721 gacttcgggt tgaggcatag gggtctccca ggtcatgagg atgcctgcct gtgcgtgctg
     6781 gttgggacac acacagtggc actgaacgag agactgcctg cgcaacgcgg gagttgcaat
     6841 acttcagatc cagttttcac catgctcttt cgcgccggtt gacgcgcatt gcaaaccggc
     6901 aagcccggtg cttgcattac gggacgacgt gacattgcag agtggggaag aaaggggagg
     6961 aacatggcgg agaccacggg atcgacggtc ccgcgccgcc agctcggaag gcaccttcgc
     7021 gagctgcgta atcaggcggg atacacgatc aagggcgcgg ccaaagcggt ggagatgtca
     7081 gacaccaaga tctggcgcat cgagacaggc cagacgtcgc tgcgatcgtt cgatgtggag
     7141 atcatgtgcc gcatctacgg tgcaccggcc gacctgaccg aagccctgat ggggctggcg
     7201 aaggagacga aggcgcgcgg ctggtggcac tcgttcggcg aggcgatccc cgagggattc
     7261 gacctctaca ttgggctaga ggaagcctcc gcccgcatcg actggtacga gccccttctg
     7321 atccccggac tcttgcagac ggaggaatac gcgcacgccg tcatgcgtgc ctacaacccc
     7381 gaggagtcgg acgaggaagt tgagcggcga gtgcgtctgc ggatgagtcg gcagcacttg
     7441 ctcacacggt acgtatcgcc cccacacctg cgtatggtcg tcgaggaagg tgtgttccgg
     7501 cgcccggtcg ggggcgcggc ggcgatggcc aagcaacttc gccaagtcgt tgagctggcc
     7561 gacttgccaa ctgtggacct gcgtgtggct catttcggta gcggcctgca cctcggcatg
     7621 ctgagcgggc agttcaccat cctgcgcttc ccggtcaacg gagatggcaa gaacagcgag
     7681 cccactacgg tgtactcgga tggcttcact ggcaacttgt acttggacaa gccccgggag
     7741 gtcgaccggt acgacgcggt gttcagcgac atgtgggacg gggcgcttga tgaagtggcg
     7801 tcccggcgcc tcatcttggg agtggcggga gagtatgagc agtaacgcgg gcccgggctg
     7861 ggtcaaaagc agctacagca gtaacggcaa ccagtgcgtc gaagtgaacg ttggttccgc
     7921 gactgtggtg ggggtgcggg acacgaagca ggagggggcg gggcccgagt tgtgggtgcc
     7981 cgctgccagt gcggcggcgt tcgtggcggg tgtggtcaac ggcaccttga gcgcgtagcc
     8041 cccggaacac aagtccccca tcggcaccgg ccggtggggg actcagccgg ggaacgcttc
     8101 gcgggccagg gtgaagtccg gggcccgatg tggcgacgac ggtggtgcgc gggcctcctc
     8161 ttgcacgtcc gacggaggaa tcgctgtgga tcagcagacc gacgaccagc cgaaggccgc
     8221 caggccagcg ctcgcatcga tgaccctgct ggtcgccgcc gtcatcgttc acgacagggc
     8281 caccgaccgc gtcgtcctcc tccaacgcgg cgagaacgcc acgttcgcgc caggcaagtg
     8341 ggacctgccc gtcggcaaga gcgaacctgg cgagccgatc accgagacgg ccgtccgcga
     8401 gttgttcgaa gagacgggcc tgaccgtgag gccggaggat ctaaaggccg cccacatcat
     8461 ccacaaagcc tggggcgtcg aagcgcccaa cggcttcctc accgtcgtct tcgcagccca
     8521 cgcatggacc ggcgaacccg agaaccgcga accccgcaag cactcccggg tctgctgggt
     8581 cgacaccgac gccatccccg aaaacttcgt ggacaccaca tcaagtgccc ttcacggata
     8641 catcgcgggc gacaccgaca tctccttggg cggctggcgg taaagagccc acgtccccgt
     8701 gctgggtcaa gagcagctac gtgtgcggcc cgacccctcg aaggtgcgcg agaacagcgg
     8761 ctcgtcccag acgcggttgg ccatggcaac aaggtggata ccctggcgga tgatctcggc
     8821 ctcgctgatg ccccggcgcc tggctgcctc cttgatgatg gccaagtcct ccgggtcggc
     8881 gtagacggtc gtgcgcttca tcggcatgta ccaaaggtag tcaaggtgtc ggtcaggtgt
     8941 accttcggcg ctgcgagccg gtgcggggcg ggcaagggcg agtttccgga gtgccaccga
     9001 ccagccctcc gggccggtgg gggtgctcag ccggggaagg tgttgcgggc gcggagggtg
     9061 tggcggcgtt ccgcgtaggc catgtcgtcg cgccacaggc ggccggccgc ggcccgcatc
     9121 agggggcgcg ccagcggggc ggcggcgcgg gccagggcga agccggggcg atgggaggtc
     9181 gcgacgacgg cctcgatcac ggcggtgcgc ggcgcgccgt cgggcccggg cccgagcggg
     9241 gtggcgtggg tttcgacgac cgagccccgg ccctcgccct cggcgatcag catggtgacg
     9301 gtgcgcggcc ccggcgcggt gaagacggcg cgcaccggga cgacggcgcg gcccgcgacg
     9361 cggaacgaca cgtcgacggt gagccgttcc ggcgcgacgg ccaccacggt caggtcgacg
     9421 aacgagtagg ggtggaacca cgcgccgtgc cacgggtcga ggcggttggc gaccacgtcc
     9481 tgcggttcgc accggccggt gccggtgaac accgcgtcca acgcccgtgc cgcttccggt
     9541 cgttgcggca cgtgcgggac ggtggagggt tcttcgccgc ccagttcgtc gagccgtacc
     9601 caggccagga cgccgtcgtc gtgcgcgggg aacggctgcc acccggcgaa cggcctcccg
     9661 tccagggcca gcccgtgcca gtggcacacg agccggccgc agcggacgcg gctctcggcc
     9721 aggggggcgc ccaggtgcgg gcacgcgccc tgcccggcca gcagccgccc cgcccggtcc
     9781 cgccaggcga ccacctcggt gccgccgatc gtgcgcccga acggccgccc gcgcgccacg
     9841 tcggtggacg cgccgagcac gtaccagttg ccggtcggct gtgcgagggc gtgcgccagg
     9901 gcttccgcga tcagggcggg gcgcgcgtcg cgccaggtcg ggcgctgcgc ctcccacgcg
     9961 gtgcggcgcc cgaggcgcag cgggtagcgg gtgcgtgcgg tcatgcggga ctccgttccg
    10021 tggcggcggc gaccagcgcg ggggtgtggc cgcccggccg cgcgcgccgt cgcgcggcga
    10081 cagcgcgcgc caggccgtcg agcgcgaccg ccgcgcgccg gtgcctcggc acgaccgcgc
    10141 ggcggtgcag cacggaccag ccgtcggccg cgaccgcgtc gaggatgccg ctgtacagcg
    10201 tgcgagcggc gcggatgcag gggcgcgcca ccgggtcgag catcgccacg cccggctcgg
    10261 ccgcgcggta gacgccgcgc gtgagcgcgg cggcggccat cagcgcggcc gtcacgcgcc
    10321 ggtcgcgccg cccggtgcgg cggctccagc acagcaggtc gcggtcgacg ccgtgcgcgg
    10381 cgagcaggtc gcccggcagg tagatccggc cccggtcgag gtcttccccg acgtcgcgca
    10441 ggaagttggt cagctggaac gcctcgccga gcgcggcggc gtgcggcgcg gcctcggcgc
    10501 gcggcacgac ggtgccgagg acgggcagca tctggaggcc gatgacggcg gccgagccgt
    10561 acatgtagcc gcgcaggtcc tggtaggtgg ggtagtcggt gaccacgagg tcgctgcgca
    10621 tcgagcgcag gaacgccgtg aagtagtccg ggtcgatgcg gtagcgggcg acggtgtgcg
    10681 ccagggcgcg cacgacgggg gcgtgcgccg tgtcgggccc ccgggcgccg tcgaacgccc
    10741 cggcagaggc ggaagtcccg ggggaggcgg acggtccggg aacggcgggg cgttcgaaca
    10801 ccgccgccac gcgcgccgcg agcgcgtcga gggcgcgggc gcgttcctcg gccggcgtgc
    10861 cgggcgcgag gtcgtcgacg atgtcgtcgg cccaccgcgc gaacccgtac agcgcgtgga
    10921 cggcgggccg ccggtcggcc gggagcaggc gggtggccag gaagtaggtg cggccgtggc
    10981 gggcgttgag ccgccggcag tgcgtgtagg cggcgcgcag agctgggttg gtgatgcgcg
    11041 cggcgtccag ttcgcgggcg gtcatgaggc gagggtgatg gtcgtgcggg agcggtcgcc
    11101 gccgcgcagg cccgtgaccc tggccgccgc cagcttcccc gagagcagca cgggcggcac
    11161 cccgacgccg ggggtcgtgc cgcagccggc gagcacggcg ttcgaggtgc cgcgcacgag
    11221 gttgcgcggc cggaacgggc cggtctgcgc gaacgtgtgc gcggcggaga acggcgtgcc
    11281 cgccgcgtgt tcctgccggg cccagtcggc cggggtgacc aggtgttcgg cctcgatggc
    11341 ggcggccagg cccgcgagcc cccggcgttc cagctcggcg agcagccggt cgcggtagcg
    11401 ggggccgagc gtgcgccacg cgtcggcgtc gggcccgatg gcggtgttgg ggcagggcgc
    11461 gagcacgtag tgcaggtggc ggcccggggg cgcgagcgag ggatcgtgcg cggtggggcg
    11521 cgtgatgagc agcgaggggt cggtcatcag ccgcccggat cgggtgagtt cctcgaacgt
    11581 gcgttcccag gcgcggccga acgacagcgt gtggtggcca agacccggcc acgtgcgcgt
    11641 ggtgcccgcg tgcagcacga cggcggaggg cgcgtggcgc agccgcagcg ggcggcgcgg
    11701 cacgcggccg agaagccggt aggcggtggg cagttccggc gtgagcacga ccgcgtcgca
    11761 cggcagccgc aggccgtcgg cggtgtgcac ggcggtgacg cggtcgccgc ggcgttcgag
    11821 gcgggtcacc gtctgccccc agtggaacgt tcccccggcg tccgtggccg ccgccgcgag
    11881 ggcgcgcggc agcgcgtgca cgcccccgcg tgggaagtac acgccggaga ccgtgtccat
    11941 gtaggcgatg acggcgtacg cggcgagcgc gcgggtgggc gacacgcccg cgtagaggga
    12001 ctggaaggtg aagacgcggc gcagccgctc gtcggacagg aaccggccga cctgccggtc
    12061 gaggcggccg aacccgccga gcgccgcgag gcgcgcgagg tcggggttga gcagccggag
    12121 cggtgagtcg aagttcgcgt cgatgaaccg gtgcagctgc gcgcggtaca gcgcttcgag
    12181 ccactgccgc agcccgcggt agcccgccgc ctcgcgcggc ccggcgcacc ggcggacctc
    12241 ggcctccatg gccgccgcgt cggtgtgcac gtcgaggtgg ccgccgtcgg cgaacctcgc
    12301 ccggtacgcg gggtgcaggg gaacgaggtc gagccgttcg cgcagcgagg tgccgacggc
    12361 ggcgaacgcc tcgtcgatca gctccggcat cgtgacgacg gtcggcccgg tgtcgagcag
    12421 gtagccgccg aggtcgacgc gcccggcccg gccgcccggc agcgccgcgc gttcgaccac
    12481 ggtcacctcg cgcccggcgc cgagcaggtg cagcgccgcc gacaggccgg agagccctgc
    12541 gcccaccacg acgacgcggc cggtcggccc ggtcagccgc ttcatcgcgg caccccggtc
    12601 ccggcggtcg gggcggtcgg ggcggtcggg ggcgccgggg cggtccggga cgttcggcgg
    12661 gtccgcgagg aaagtaccgg catcgcgtgt ccttccgtgg ttccgtgcgg cggggccgcc
    12721 accgtcaggg cggcccgccg tgcaggcgtt ccccggtccg gggcggcacg gtcgcgcggc
    12781 ggccggattc agcccgttcg gcccacgggg tcgttcgctg ctctcggggc gcccggcgcg
    12841 cgcccgcgct cggacggcgc gcgcgccggg cggccgtcag ggcgtctcgg ccgcctccgc
    12901 cgccgcgtgg gcctcggccg ccgcgaggcg ggcgcgttgc ggctcgaccg tgtacttcgg
    12961 gtcgcgcacc gacgccagcc ccgcgtggaa caggccgaag cgcgtgcagg ccgaggcggc
    13021 cagcagcgcc gcgccgctga gcgccgccgc cgcgcggctg cgcccggcga gcccggccgc
    13081 gccggccgcg cccgcggcgc cgagcaccga ggcggcgcgc agcaggcgcc cggccttccc
    13141 ccgccggtag gtctcgtcga ccggcccggc gcggcggtgc agcgcccgca tggcggcgaa
    13201 ctcggcggcc gtgcccagca cggcggcgcg ccgcgccggg ccgctctcgc gccccggcgc
    13261 ggccagcagc gccatgccgg ccgcggcggc cgccgccgag ccggtgaaca ggtacggcag
    13321 ttccctgtgg ccctcgtgcc acgcgggcac cgccgtgtcc gcgaacagca cgcccgtgta
    13381 ggcggcgacc gccggcccga acaccgccgc gccgcaggtc gcggcccggc cggtgcgggg
    13441 gaacaggccg gtcgtgtcgg tgacggcggc gacgccggcc agcgggccgt aaccggcgag
    13501 cagccacgag ccgatgctca tgggggaggt cggcttgatc acgcgcagca tgttcaggaa
    13561 gcgcgccggg cggccgaggt cgtgcacgag cgccacgacg gacagcgaga ccgcgccgag
    13621 cgagctgagc ttcatcgccc gcgcggtggc gcgccgcccg gtcagctccg caccggcggc
    13681 gagcaccgag ccggccccgg cgagcccgcc gaggaacagg tagccggcga tgtccgtggc
    13741 cgcccagtgc ggggccttga gcaccggcct gccgtagtac gacgtgaacg cctcgccgtc
    13801 ccccgggccg ccgccgggtc cgcctcggga acgccgccgg cccgccgggc ccgccgcccg
    13861 ccgttcgcct gagccagtgc cggtgctgaa cgcgtcggcg ccgtacggcc gttggccgtc
    13921 cggcggggca ccgtccggga cggccccggg accgcccggc atgccgttgc cgaacagcgc
    13981 gtggctgccg ggccgttcgt tgcgcaggcc cgccctggtc acctcggcgt cgctcatcgc
    14041 ctgcctcccg cgaacatcgc ggcgagcccc gtcagcagcg ccgccgccgc gacgcccgcg
    14101 tgccgccaca tcgcgggcag gtcccgcgtg gtgacctgcg ggtccggcgg cagcccgtac
    14161 acctcgggct cgtcgagcag caggaagaac gcgcccgcgc cgcccacccc gtccgccggg
    14221 tcctcgccgt acaggcgcgc gtcgggcacg ccggtcgcgt gcagttgcgc gacgcgctcg
    14281 gccgcgcgct cccgcagcgt ctccagcggc ccgaactgga tcgagtcggt cgggcacgcc
    14341 ttggcgcagg cgggttcgct cccggcgccg agccggtcgt agcacagcgt gcacttccag
    14401 gcccgcccgt cgccctcgcg ctgctcgatc accccgtagg gacaggcggg cacgcagtag
    14461 ccgcacccgt tgcagatgtc ctcctgcacg acgaccgtgc cgaactcggt gcgcagcagc
    14521 gagcccgtcg ggcacacgtc gaggcacgcg gcgtgcgtgc agtgcttgca cacgtccgag
    14581 gccatcagcc agcgcatgtc gggctgcgac tgctggccgc ccagcggctt ggcctgctcg
    14641 atgaacgcca cgtgccgcca cgtcgaggcg ccgagcgcgc cggtgttgtc gtagctcatg
    14701 ccggtcaggt cgagcccgtc ctcaggcacg gcgttccact ccttgcaggc aacctcgcac
    14761 gccttgcagc cgatgcacac ggaggtgtcg gtgaagaacc cgacgcgctc gggcgggtcg
    14821 gtgtgccccg cgtcggccgc gacatcgggc tcgggcccgt acagcaggtt cggtcgttcc
    14881 gtcgtcagat tcggtcgttg cgtcgtcagg tccggtggtt ccgtcgtcat gggtcagacc
    14941 tccaggcccg ttcgctcgtc ggcgcccgcg cgcctgcggt agtcctcgac cagggcccgc
    15001 agcgcggggc cgcgcgggcg gcgcccaggc cggatgtcgg cggtgagcgc cttgacctcc
    15061 tggatgtgca cgttcgggtc gagcacgatg gcggacagct cgttcgccgc gtcgcccgtg
    15121 ctgtagccgt tgggtcccca gtggtagggc aggccgatgt ggtgcaccgt gcggccgtcc
    15181 gcgcgcagcg gcgccatccg ctcggtgacc agcacccgcg cctcgatggc gctgcgcgcg
    15241 gtgatgatcg tcgcccagcc cgcgtgggcg aggccgcgtt ccgccgcgag ctcgggggac
    15301 acctcgcaga acaactccgg ctggagttcc gccagatagg gcgaccaacg ggtcatgccg
    15361 cccgccgtga agtgctcggt gagccggtag gtcgtcacga cgtacggata gacgtgcgag
    15421 cccggggccc cgttcgccgg gtggtactcg ttgccctcgc gggggaacgc cagccgtacg
    15481 ggggagcgcg ggtggtgcgg gtgcagcgcg ttcccgaacg gcgagtcctg cggctcgtag
    15541 tgcgtcggca tcgggccgtc cacgagcccc gccggggcgt agagccagcc cttgccgtcg
    15601 ccctgcatga tgaacgcgtc gtcgccgcgc agcgcggcca cgccgaacgc gttctcgtcc
    15661 gggacgtggt caggcgggca cgtgaggggg aagtccggct cgtcgtggcc ggtccagcgg
    15721 cccgcgtccg cgtcccacca cacgtacgcc ttgcgttcgc tccacggggt gccgtcgggc
    15781 gcggcggagg cgcggttgta cagcacgcgg cggttcgcgg gccaggccca cgcccactcg
    15841 gcggccaccc agtcctgctc ggtgtgcggc ttgcggcgcg cggcgcggtt gacgccgtcc
    15901 gcgtacacgc cgcagtagat ccagcagccg caggacgtgg agccgtcgtc cctcaactcc
    15961 gtgtacgccg acagcggcgc gccgtcgggg ccgcgcccgt tgatctcggc gaggaccgcg
    16021 tccgcgatcg gctcgtcgtg cgcgccggtc accgggtagt cccaggccag gtcgaggaac
    16081 aggcggtcgg ccgggtcgtc ggagccggcc agcttctcgc ggatgcggcg gtgcaggtgg
    16141 tgggcgaacc acagctcgct gcgcgcgtcg ccggccggct ccacggcggc gtggtgccac
    16201 tggagccagc ggttggtgtt ggtgaacgag cccgacttct cggcgtgcga ggcggcgggg
    16261 aagaagaaca cctcagttcc gatgtcctcc gtgcgcagct ccccggtctc gatctccggc
    16321 ccatcgagcc accaggtcgc ggactcgatg agcgagaagt cgcgcaccac gagccagtcg
    16381 agccgcgcca tgccgaggcg ctggaggcgg gcgttcgccg agccgacggc cgggttctcg
    16441 ccgagcagga agtagccctt gcagacgccg tcgagctgcg ccatgacggt gtcgtacgtg
    16501 ctgtgcgagc cggtgaggcg cggcaggtgg tcgaagcaga agtcgttctc cgcggtggcc
    16561 gcgtcgccgt agtacgcctt cagcaggctg accatgtagg cgttcatgtc ggcccagtag
    16621 cccttgcggg cgcgcaccgc gcgcacgaac gagtccaggt cctggtgggc ctgcgcgtgc
    16681 ggcatcggca ggtagccggg cagcaggttg aacagcgtcg ggatgtcgct cgacccctgg
    16741 atgctggcgt ggccgcgcag ggcctggatg ccgccgccgg ggcggccgat gttgccgagc
    16801 agcagctgga gcacggacgc ggccctgatg tactgcgagc cgacggtgtg ctgggtccag
    16861 ccgacggcgt acacgaacgc gccggtgcgt tccgggcccg agttgcgcgt caggatgtcg
    16921 cacacctgcg cgaaccgttc gggggaaacg ccgcacaccc gttcgaccat ctcgggtgtg
    16981 tagcgcgcgt agtgccgctt gagaatctgg aacacgcagc gcgggtgcgt cagcgtctcg
    17041 tcccgccggg ggcgcggcgt gacgtcctgc ccgccggagc cgtgcgactc cgagccgccc
    17101 gccgcgtgct cgatcgccgc gtcgtcgagc cgcaggttgc ggtgcgggtc gggctccccc
    17161 gccagcgaac gcaccgccgc gccctcgtac tgccagctct ccgggtcgta gtggcggccc
    17221 tcctcgtcga ggccggagaa gaccccggcc aggtcctcgg tgtcgcggaa gtcctccgag
    17281 acgatggtgg ccgcgttcgt gtaggccagc acgtagtcgc ggaactcctt gccctcgctc
    17341 aggacgtggt tgatgatccc gccgaggaac gcgatgtcgc tgccggccct gatgccgacg
    17401 tgcaggtcgg ccagcgcgct ggtgcgcgtg aaccgggggt cgacgtgcac gatcgtcgcc
    17461 ccgcgcgcct tggcctccat gacccactgg aagcccaccg ggtgcgcctc ggcgtagttg
    17521 gagccctgga tcacgatgca gtcggcgttc tggaggtcct gcatgaacgt cgtcgcgccg
    17581 ccgcgcccga acgacgtgcc gagcccggcg accgtcgaac tgtggcagac ccgggcctgg
    17641 ttctcgatct ggatgatgcc caggcccgtg aacagcttct tgagcaggta gttctcctcg
    17701 ttgtccagca ccgcgccgcc caggctcgcg atgccgagcg tgcgcgccac gcgcgagccc
    17761 tcgacctccc actgccacgt ctcgcggcgg gttttgatga cgcggtccgc gaccatgtcc
    17821 atggcctcgt cgaggccgat cggctcccag gcggtgccgt gcgggcggcg gtagagcacc
    17881 tggtggcgcc tggcgtcccc ggtgacgagc tggagcgtcg cggaaccctt cgggcacagc
    17941 cggccccggc tcaccggcga ggccggatcg ccctcgatct gcacgatccg ctcgtccttg
    18001 acgtagatct gctggccgca gccgaccgcg cagtacgggc agatcgagtc caccacccgg
    18061 tcggcggtgt ccgtcctcgg ccgcagccgc gcggtgcgcg cggagcgcgc ggcggcgccc
    18121 cggcccagcg ggtcggtgcc ggtcagctgc cggtacacgg gccagtcctg aatccacgtg
    18181 cgcacgccca tcgcccaccg cgcctttccc gagccgcccc acgggtggcc gccggtcctc
    18241 cgtgcccgcc gctcccggcg ccgccggcac ctggtgcgtc tccggcgatc atgcggcgcg
    18301 ttcggggcgg gcgcatccgg ggcgtgtccg aacgggcggc gggcgagcgg gccgaacggg
    18361 cggcggggcg ttcctccggc cgcggggcgg ggcgttcggg gtggggcgtt cctccggcgg
    18421 gggcgcgggg gcgctggacg aggggcaggg gcgcgcgcag aatcgggccg gggagcgcgc
    18481 gggccggcgc gcggtgccga cagggggcgc ggatggcgga catcgagtgg gcggtgcagg
    18541 agtgccggga gtgcgggcac ccgcgcgccg accacgatcc gctggtcagg gtcgagggca
    18601 ggtgccgggg aacgaccgct gtcccggccg gtggccgcgc cccccggccg tgcgcgtgcc
    18661 gtgagttctg gcccaagccg caggacgtgg gcggccccgg cacgtggccg tgcgcgtcgt
    18721 gcggccaccg gcggcacctg ccggccgcgt gccgcgcgcg tgcggtgggc ggcggcgacg
    18781 ggctcaggaa ctgccggtgc ggctacgagc cgccgcgccc ctggctcgac ccgatcggct
    18841 gacccgcacc tgctgcccgg ccgccgcccg gccgccatcg ggcggcgggg ccccggccgc
    18901 gctcagggca tcccgtcgtc cggccgcacc ggttcgaccg cttcgaccgg aacgttcggg
    18961 tggctgcccg cgtcctcgcc cccgtcgctc gggaactccc gcgggtcgag cggctgcggc
    19021 gacggggccg gaacgggggc gggcgtggcc tcctgatgag gcaggggaag gtcggaggga
    19081 acgcccgcgg gcctggtggg cggcggctcc ggcgccctgc cgccgagcgc gagcagggcc
    19141 gcgaccaccg cggcggccag gccgagcagc gcggcggccg tggcccgtcc ggacaggacc
    19201 cggaggcgcc ggggggcgtg cgcggagggc gggcgggggg cgcgcaggtc gtcggcggtg
    19261 acggtctcgg cacgggcccg cagggcggcg gccaggagcc gttcgatcgc ttccgggtgc
    19321 tgatcgcctc caccgggcgt gctcatgggc tggtctccag gtgtctgcgc agggccgtca
    19381 acgcccggct cgcggtggac ttcaccgtgc cgggcgacag gccgagggtg tcggcgatct
    19441 ggatctcgga gaggccggac cagtaccgca gcacgaggac ttcgcgctgc cgcctggtca
    19501 ggcggcgcag cgcgtgcagc accgtcctgt gctcctcgcg cagcagcacg tactcgtcgg
    19561 ccgaggggcc gtgccccggc cgttcgggca cgtgcgcgcg cacggtcctg cgccggcgca
    19621 gcacggaacg ggccgcgttc accacgctgg tgcgcaggta cgcctccggg gcgtccacgg
    19681 cgtcgagttc ggggccgtgg cggcgcagca gcgcggcgaa cgcgtcctgc acgacatcct
    19741 cggccgtggg cacgtcgtcc accaggaaca gcgcgagccg gaccaggtcg aggcggctgt
    19801 ggtggtagag gtcgtcgatg tccggccgcc gcgcgtcccc ggccccgccg ccgggcggcg
    19861 agggcggcgg cccgccggac ggctcgggcg cgggtcgcgt gccgcgccgg ccggttccgc
    19921 cgcgcaccac cgggagtccc gtcatcgtgt tcgtttcctc gggagggggc ggacggcgcg
    19981 cggggcgagg ccgccgggtg acgggctcac ggccgtcacc cggcggctcc ggcggcgccg
    20041 tccggtcagg cgtcagcggc cggaacgcgc gggcgggtcc tcgtccacgg gcggtgcctc
    20101 gcgcggcacg ggcacgggcg cgggttccgc gccggactcc tcggggcagt cctcggcggg
    20161 gacgggcacg ggctcctctg cgggtgcttc ctcggccgga acgggcacgg gctcggcacc
    20221 ggagtcctcg ggaccggcct cgtccggagc ggggacgggc gcgggcgcct cctccgccgg
    20281 tgcttcctcc gccggtgctt cctcagccgg aacgggcgcg ggctccgcgc cggacgacgc
    20341 cggggacgcg ttggtggcgt gggcggtcag gacgccgccg acggtgacgg cgagcccggc
    20401 ggcggccgtg acgagggcga cgcggaggcg ccgggcgccg gaacgcggcg gcccggcctg
    20461 gggtgtgggc atgctgctcc ttcggttctg tgggcggacg gctgcgcgaa cggtcgcgga
    20521 gccgtccgtg ggtggaggcg cctccactcc ccacagacgt gcggccgccg gtggcgttgc
    20581 gggtggccga gggattttcc tgtgaggggc gtcacaccgg cggccgggcg gatcggtggg
    20641 tccggccgtg cgtcagcgcc ccgcgacgcg ttcgcgcccg accgcgaacg cgtcgcggaa
    20701 caggaggagg acgagcaggg ccacgccgac gagcgcgccg ccggcccaca gcggcccgag
    20761 gccgccgccc tggccgcgca gcgtggccgc ggcgatgagc ggcccggccg cggcgccgac
    20821 gttgagggcg gcggtcgcgt aggagccggc catggtcggg gcgcccgccg cctcgtggag
    20881 cacccgggcg atcagggtgc tgcccacggc gaacgacagc gcgccctgga cgaacagcag
    20941 cgcgaacagc gcgagcggca cctcggccag cagcgccagg gccggccagc cgatgagcag
    21001 cggcgggccg ccggccgcca ggaccaggcc gggcagccgg tcggacagcc gccccgcgac
    21061 gttga
//
