LOCUS       NZ_CP084541            22292 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces marincola strain SCSIO 64649 chromosome, complete
            genome.
ACCESSION   NZ_CP084541
VERSION     NZ_CP084541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Strepomyces indimicinicus sp. nov., an antibiotic producing
            actinomycetes isolated from the marine environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Sciences, 164 Xingang West Road, guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. V6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 444.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020410765.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,763
            CDSs (total)                      :: 5,689
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 74
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 21 of 77
            Pseudo Genes (incomplete)         :: 60 of 77
            Pseudo Genes (internal stop)      :: 2 of 77
            Pseudo Genes (multiple problems)  :: 6 of 77
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:57:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3563521
            Orig. end                         :: 3585813
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22292
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22292
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22292
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12292](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12292
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            32..1606
                     /locus_tag="LC193_RS15445"
                     /old_locus_tag="LC193_15445"
     CDS             32..1606
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007459524.1"
                     /locus_tag="LC193_RS15445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15445"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_226074788.1"
                     /transl_table=11
                     /translation="MTLRCLVTGATGYLGGRLVPELLAAGHTVRCLARTPARLNDRPWA
                     DRVEAVRGDVTDPASVRSALEGIEVAYYLVHALGGRGAFEEIDREAAHVFAAAARDAGV
                     RRLVYAGALTPEGVPERELSPHLRSRAEVGHILLDSGVPTAVLRAAVVIGSGSASFEML
                     RQLGERLPVMVTPRWVRTRVQPVAVRDMLRVLAGSAELPADVNRAFDVGGPDVVTYETM
                     LRRYAVRAGLRRRLIVPVPVLTPGLSSLWVGLVTPLPGRLARPLVESLRHEVVCRERDI
                     ERYVPPPPGAPLGLDAALDAALDTTSGPTPDLSRDRARARARERPGERPGSRERERERE
                     VESVPGGSRDRAPADAAAGPLPSDPAWAGGSLYTDRRERAVDTSPEALWRVVEGIGGEN
                     GWYSSPVAWAVRGWLDSLVGGGGLRRGRRDAARLRVGDALDFWRVEALEPERLLRLRGE
                     MRVPGTAWLELCVDRDDEGRTVYRQRALFHPRGLAGHAYWWAVAPFHAWVFGGMVRTIT
                     STAQAEG"
     gene            1614..3041
                     /locus_tag="LC193_RS15450"
                     /old_locus_tag="LC193_15450"
     CDS             1614..3041
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016577341.1"
                     /locus_tag="LC193_RS15450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15450"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_226074789.1"
                     /transl_table=11
                     /translation="MSRDRERAQHEGAKGGRGGSGAKHDGVNGANGARAVSVALFTADL
                     RLRDNPVLHGALRDAPEVVPLFVVDDGVRAAGFRVPNRAAFLADCLADLDAALRERGGR
                     LVVARGDVVAETCRVAAAVGAATVHLAADVSGYAARREERLRAALAADGRRLTVHDATV
                     TAVPPGVIAPQGKDHFAVFSPYFRRWDAMSLRDVLRAPRTVRVPEVRSARLPAASDLAS
                     GTPSPGLPEGGESAARRRLRAWERGPLDAYADRHDDLAGDGTSRLSPYLHFGCVSANEL
                     VHRSRRHGGAGADAFVRQLAWRDFHHQVLAARPDAAHRDYRDRRSEPWRNADALADAVT
                     AWREGRTGFPIVDAAMRQLAHEGWMHNRGRLLVASFLTKTLNVHWRVGARHFLDLLVDG
                     DLANNQLNWQWVAGTGNDTRPNRVLNPLSQARRFDPRGDYVRRWVPELAGVEGRAVHRP
                     WRLDADLDYPDPIVEPW"
     gene            3197..3421
                     /locus_tag="LC193_RS15455"
                     /old_locus_tag="LC193_15455"
     CDS             3197..3421
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS15455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_15455"
                     /product="hypothetical protein"
                     /protein_id="WP_226074790.1"
                     /transl_table=11
                     /translation="MATGSIIFRSADGRTQVIDEPENGGRFPLGEAGLLENNTDRELRL
                     IPPAGQGDPAVLQPGGSAQIEAGSAVHVV"
     gene            complement(3468..3821)
                     /locus_tag="LC193_RS15460"
                     /old_locus_tag="LC193_15460"
     CDS             complement(3468..3821)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061599.1"
                     /locus_tag="LC193_RS15460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15460"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_226074791.1"
                     /transl_table=11
                     /translation="MRDVRHPSTGEMTLIAAMSALSDPVRIGLVRLLSDGAERAWGDLR
                     APVAKSTLSHHLRVLRDAGITRTRQEGTRCFVELRRADLDARFPGLLDAVLDAADREDV
                     GHDVLAASGAPGA"
     misc_feature    3827..3840
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.93"
                     /tool="antismash"
     gene            3878..4648
                     /locus_tag="LC193_RS15465"
                     /old_locus_tag="LC193_15465"
     CDS             3878..4648
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (14-172). E-value: 5.5e-11.
                     Score: 34.6. Matches aSDomain:
                     nrpspksdomains_LC193_RS15465_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430944.1"
                     /locus_tag="LC193_RS15465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15465"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_226074792.1"
                     /sec_met_domain="adh_short (E-value: 2.5e-32, bitscore:
                     110.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4.9e-35, bitscore:
                     120.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQHSPAPGRFHQRVTIVTGAGSGIGRAAALALAAEGAHVLGVGR
                     RPGPLEETARAHPGIVAFPADIRAPGAAEAVVGAAVDRWGRIDVLVNNAGGMDAMTLPE
                     VTAERVARMFDLNVIAPSLLARAALPHLRETRGSILNVSSIYGHRPGAGVSHYAASKSA
                     LEQLTRSWALELAGEGVRVNALAPGPTESEALHAAGLPEEVIAAVKAEEAARIPLGRRG
                     EPEEVAAWLLHLADPAATWFTGQVLAVDGGLNLT"
     aSDomain        3920..4393
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC193_RS15465_PKS_KR.1"
                     /evalue="5.50E-11"
                     /label="LC193_RS15465_PKS_KR.1"
                     /locus_tag="LC193_RS15465"
                     /protein_end="172"
                     /protein_start="14"
                     /score="34.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VTIVTGAGSGIGRAAALALAAEGAHVLGVGRRPGPLEETARAHPG
                     IVAFPADIRAPGAAEAVVGAAVDRWGRIDVLVNNAGGMDAMTLPEVTAERVARMFDLNV
                     IAPSLLARAALPHLRETRGSILNVSSIYGHRPGAGVSHYAASKSALEQLTRSWA"
     gene            complement(4698..5273)
                     /locus_tag="LC193_RS15470"
                     /old_locus_tag="LC193_15470"
     CDS             complement(4698..5273)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985704.1"
                     /locus_tag="LC193_RS15470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15470"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_226074794.1"
                     /transl_table=11
                     /translation="MVRRNDERRAALLDAAIEVLAQEGARGLTFRAVDAGAGVPKGTAS
                     NYFANRDELFTQVGERFYERLQPDEAAVARLRDAPRDRDTYVTLMRELVGRVSAFRTGY
                     LALLELRLEATRRPRLREVLTARVRADADANVAYHEASGLPGDATAVRLLMLTLNWLIL
                     EQLTLPDLYSEDERERLVQAAVERIVLP"
     misc_feature    5335..5348
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.11"
                     /tool="antismash"
     misc_feature    complement(5337..5350)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.08"
                     /tool="antismash"
     gene            5340..5930
                     /locus_tag="LC193_RS15475"
                     /old_locus_tag="LC193_15475"
     CDS             5340..5930
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009714948.1"
                     /locus_tag="LC193_RS15475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15475"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_226074795.1"
                     /transl_table=11
                     /translation="MRKLVYYIAVTLDGRIAGPGGEYDFFPLGNEEQAAGYAERMNARY
                     PEFLPTAGREMFGLADVPNRRCDTVVMGRGAYLPGLDAGMTSPYAHMRQYVVSRTLDVG
                     IDPDVTVVPSDPLGLVRRLKQEDGGLDIWLCGGGRLAGELLPEIDELIIKSYPVVAGAG
                     PSVFDGAFDPTLFTPTARETFDNGVLVTWCTAR"
     gene            complement(5994..6830)
                     /locus_tag="LC193_RS15480"
                     /old_locus_tag="LC193_15480"
     CDS             complement(5994..6830)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048071.1"
                     /locus_tag="LC193_RS15480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15480"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_226074798.1"
                     /transl_table=11
                     /translation="MRTASPGSPGNLMSPGIAATFDELVAEGEAVPTEGWDFSWFAGRA
                     TEERPAWGYSSLLADRMRAAEAALDMQTGGGEVLAAVPVLPPVLAATESWPPNVGIARR
                     NLAPFGATVVAMTDDAADLPFPDGHFDLVVSRHPVVTRWDEVRRVLRPGGTYLAQHVGA
                     GSVRELTEFMMGQNPFPPPPPARPFTTRSGATPTGAVAVAESAGLVVVDVRQQALRMEF
                     HDIAAVVHFLRKVIWTVPGFTADAYRERLVELHDFIERHGPFVAHAQRFLIEARRP"
     gene            complement(7022..9649)
                     /locus_tag="LC193_RS15485"
                     /old_locus_tag="LC193_15485"
     CDS             complement(7022..9649)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014181205.1"
                     /locus_tag="LC193_RS15485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15485"
                     /product="rhamnogalacturonan lyase"
                     /protein_id="WP_226074800.1"
                     /transl_table=11
                     /translation="MTPADRRRRARHRRLIAAPLAGLMTAGLLAAAGTAPARAAEPAAQ
                     PAARGTERPAPGGVQLEHLDRGLAAVATEEGVFLSWRLLATEVTGHSETGLTGADFHVY
                     RDGELLGTVTESTNYLDAEAPAGAEYRVAAVVDGVEVDLSEPVAPWSDGYYELPLDKPA
                     DGVTPAGEAYTYSANDVSVGDVDGDGQYEYVVKWYPSNAKDVSQVGYTGNVYLDTYRLD
                     GTLLHRVDLGVNIRAGAHYTQFLVHDFDGDGRSEIMFKTAPGTKVTRYHPDGRVASERH
                     ITMPREDIRAGYGHDDDYRMSAEDYYAHVVGMFEDWHEHPEVVAGNWPATLEEAFGIAP
                     AHDYPLSREDAEALADHFMDEYAPSRSARNNLRAFEGFILEGPEYLSVFDGATGRELDT
                     VRYEPGRHDDGLMWGDYAMARIEPGNRVDRFLSTVAYVDGQHPSAVFARGYYTRSTLVS
                     YRWDGHRLREDWNVDSGWTPMSNPFNDGPHGVDGTDPEFGTLTTQGFHSLSAADVDGDG
                     RQEVVYGSATIDDDGSLLYSSFAEMPPGSADPGAQARLGHGDAMHVTDIDPARPGLEIY
                     TVHEGGASAPLGYALRDAATGEVIYGEYTGVDTGRGMIGDVDPDEPGIETWANHPEGGT
                     DPDGVGLWSADGRRLGERTPGTNQSIRWAGDLTAQMVAGYGYLGEDTVVEDWRRGTLLT
                     AEGTRTNNHTKGNPSLVADVLGDWREELLVPTADSTGLRLYLSTELTGHKLYTLMHDPQ
                     YRAEVARQQTTYNQPSYTGFYLASDMDFSAVPVPDLWTPGGVAALADDLAGRVAGGEVS
                     FLSALLLKPWTVKAELHMARGDHASAARALERFTATLEHLRGVADPARAALTHRAETLI
                     RTLR"
     misc_feature    9779..9795
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.5"
                     /tool="antismash"
     misc_feature    complement(9785..9798)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(9910..9928)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(9913..9928)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.4"
                     /tool="antismash"
     misc_feature    9917..9931
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.4"
                     /tool="antismash"
     gene            10001..12292
                     /locus_tag="LC193_RS15490"
                     /old_locus_tag="LC193_15490"
     CDS             10001..12292
                     /EC_number="4.2.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515109.1"
                     /locus_tag="LC193_RS15490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15490"
                     /product="terpene synthase family protein"
                     /protein_id="WP_226074801.1"
                     /sec_met_domain="T1TS (E-value: 1.8e-81, bitscore: 273.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPAFYMPYPARLNPHLDAAREHSPRWAARMGMLEGSGIW
                     TGADLDAHDYPLLCAYTHPDASAEDLCLVTDWYVWVFFFDDHFLETFKRTQDRPGGKAY
                     LDRLPAFMPLDPAAGTPEPTNPVEAGLADLWARTVPAMSAAWRRRFAESTANLLNESLW
                     ELSNINAGRVPNPVEYIEMRRKVGGAPWSAGLVEYAARAEVPAAVAASRPLRVLRDTFS
                     DGVHLRNDLFSYQREIEDEGEMSNGVLVLETFLACSTQEAAEAVNDLLTARLQQFEHTC
                     VTELGPLFAESGLDAASCAAVLAYAKGLQDWQSGGHEWHMRSSRYMNGAVGGGAAHAHA
                     PAPGLAALPTLPGLPPGLGTAALRAPGGARRGPGGVTTTRRAEAARARRFRHVPHRRVG
                     PSLLPDFPMPFDLRLNVHLDGARTRLAAWAHRVGILDGAPWTEAKLYDYDLPLCAAGLA
                     PDAPADALDVVSGWLAWGTYGDDLYPVLFGRTHDVAGARAVTERIAQFMPVEDPNAMPV
                     PVSGLERGLADLWPRTAGPMTLPARRRFRETIEVMTASWVWELDNQAQNRIPEPVDYVE
                     MRRQTFGSDLTMCLARLGHGPKVPQEVYRSGPISSLENAAADYACLMNDVFSYQKEIEF
                     EGEIHNGVLVVQDFFDCDYPAALRVIADLMAERMRQFQHVAAHELPVLYEDFGLDDEVR
                     GILDGYVRDLENWLAGILNWHRFCRRYRESDLRRHAQGALWPLGAPTGLGTSAARITRL
                     LGPPAARRAS"
     misc_feature    complement(10002..10017)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            complement(12431..13288)
                     /locus_tag="LC193_RS15495"
                     /old_locus_tag="LC193_15495"
     CDS             complement(12431..13288)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042199.1"
                     /locus_tag="LC193_RS15495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15495"
                     /product="maleylpyruvate isomerase family
                     mycothiol-dependent enzyme"
                     /protein_id="WP_226074802.1"
                     /transl_table=11
                     /translation="MDTSRGGGAGHAWLGAPIDARPLFAPEHAALMALLRDLAPVDWGR
                     EAVPGWTVRDLAAHILGDCYGRLARARDGHRGGPSPAPGEALEAFIHRANAEWVAAFAR
                     VSPAALTDTLDLVGGQTVRYFEATDPDSPSLGVSWAGADPAPMWLDSARELTEFWTHRQ
                     QIRHAAGRGTDPDPRLWSVVLDTFMRALPHTLRAVDAPVGTQLRVRIDGPAGGTWTATA
                     TGERWSLAPPAGEHPAATVELDPETAWRLCTRGIAPDDALTLARLHGDRELAAAACRIV
                     SIVH"
     misc_feature    13406..13420
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     gene            complement(13506..13901)
                     /locus_tag="LC193_RS15500"
                     /old_locus_tag="LC193_15500"
     CDS             complement(13506..13901)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986497.1"
                     /locus_tag="LC193_RS15500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15500"
                     /product="hypothetical protein"
                     /protein_id="WP_226074803.1"
                     /transl_table=11
                     /translation="MRTSVLRAVGVATTAYGVAVTVRPGLLAKPSGLAGPDGRTAAEVR
                     TSLRPLGLREAACGLALALAPRGAALRTAAAVRLAADFGDAVLLGATLPGPARRGGAVA
                     VSVGWGALTLAGLLLPESPNARRAAAR"
     gene            complement(13958..15220)
                     /locus_tag="LC193_RS15505"
                     /old_locus_tag="LC193_15505"
     CDS             complement(13958..15220)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010041661.1"
                     /locus_tag="LC193_RS15505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15505"
                     /product="S8 family peptidase"
                     /protein_id="WP_226074804.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 3.7e-20, bitscore:
                     70.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRRPRTLRRFRTVRRPGASPVPRGSGRSRTVAVLTAALLLPATA
                     AALPAPTGAAPEGHVLGAPGRDAVDGSYLVLLADGGEPAAEAGARLADRYGVRVVDAYD
                     AALTGLHVHATAPQARRLAADPAVRAVKQDSVIRALPAGTQPNPPNCGLDRIDQPDLPL
                     DGSFTYPDSAGAGATAYIVDTGIAYGHADFGGRAGPGYDATGGNGSDGNGHGTWAAGLV
                     GGTNHGVAKEADLVSVKVLNDAGSGTVAGVVAGINWLTADAQGEPAVALVTLGGVASQV
                     LDQAVRTSIASGVTYAIAAGGSGDDAGRYSPGRVTEAITAAASDCRDRVAGFTNHGPVV
                     DLFAPGVGIASTWPNGTAVLSGTSGSAAFTAGVAVLYLGDHPSASPAQVGQAIDQAAAV
                     GRLTGVPAGSPNKLLQVVPVD"
     gene            complement(15376..15771)
                     /locus_tag="LC193_RS15510"
                     /old_locus_tag="LC193_15510"
     CDS             complement(15376..15771)
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014906.5"
                     /locus_tag="LC193_RS15510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15510"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_226074805.1"
                     /transl_table=11
                     /translation="MLARSEHVHSLLLRAGLDGARLTVAVGALTYFVQGYTAAENVWRV
                     HRRDPQDEAELRAGAQQFIEQREDRYPTLAGHARLVDDDFDGSFLLGLETILDGIAAHA
                     GGRGTGAAGRAAGLAEREDARGHEGAV"
     gene            15751..15996
                     /locus_tag="LC193_RS15515"
                     /old_locus_tag="LC193_15515"
     CDS             15751..15996
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS15515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_15515"
                     /product="hypothetical protein"
                     /protein_id="WP_226074806.1"
                     /transl_table=11
                     /translation="MFGAREHSELAAHLSRWALLSDDETGAALGTLRATGMALYVLGYF
                     HGWRLLDSWLATADRDVRVRRLLTEQLLPADVRPAG"
     gene            16061..16669
                     /locus_tag="LC193_RS15520"
                     /old_locus_tag="LC193_15520"
     CDS             16061..16669
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324156.1"
                     /locus_tag="LC193_RS15520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15520"
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_226074807.1"
                     /sec_met_domain="Mac (E-value: 2.8e-08, bitscore: 32.3,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRDDERDVLDRIGRGLVYTESEAVFLDERRRADLIFAYNHTPPG
                     DTRKRRSLLRAILGSVGERPALHPPFSAAFGSNVHIGDDFFGNVNLAFVDDVEIRIGHG
                     VMTAPSVTLTTTGHPVHPARRVDFARFSEPIVIEDKVWIGSNVVVLPGVRIGYGSVIGA
                     GSVVAKDVPPMVVAVGTPCRVLRDITDDDLTTRTAAADR"
     misc_feature    complement(16108..16123)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.4"
                     /tool="antismash"
     gene            complement(16775..19132)
                     /locus_tag="LC193_RS15525"
                     /old_locus_tag="LC193_15525"
     CDS             complement(16775..19132)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019548366.1"
                     /locus_tag="LC193_RS15525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15525"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_226074808.1"
                     /transl_table=11
                     /translation="MPADPFQQPAAPPRGQAAHPPEAAAGPVAADSHDVIKVRGARENN
                     LRDVSLDIPKRRLTVFTGVSGSGKSSLVFGTIAAESQRLINETYSAFVQGFMPSLGRPD
                     VDALHNLSAAIVVDQERMGANSRSTVGTVTDAYTMLRIVYSRLGTPHIGTSTAFSFNSP
                     EGACQDCEGMGQVSRIDIDQLVDRELSLNEGAITVPGFGVGTWYWQVMAASGLFDNDMK
                     LKDYPAELWEDFLHKPATKIKAGTNTITYEGLVTKVNRVYLSKDRETMQTTLRAFVDRA
                     VVFAACPTCRGTRLSAAALSSTINGVNIAECSAMQISDLAEFVRGLDAPSVAPMLGALR
                     DLLGSLVEIGLGYLSLDRPSGTLSGGESQRVKMVRHLGSSLTDVTYVFDEPTTGLHPHD
                     IQRMNDLLLRLRDKGNTVLVVEHKPEVVAIADHVVDLGPGAGTSGGEICYAGDVAGLRA
                     SGTRTGRHLAHRAALRETVRTPRGHLSITGAATHNLRNVDVDIPVGVLTVVTGVAGSGK
                     SSLIHGALPGRAGVVVADQSAIRGSRRSNPATYTGLLDPIRKAFAKANGVKPALFSANS
                     AGACANCNGIGLVYTDLAMMAGVASVCEECEGKRFTPEVLTYTLDGKDISEVLEMPVAE
                     AHKFFRTGQAQAILSRLMDVGLGYVRLGQPLTTLSGGERQRLKLAIHMAEKAATYVLDE
                     PTTGLHLADVDQLLALLDRLVDAGNTVIVIEHHQAVMAHADWLIDMGPGAGHDGGQVVF
                     TGTPAELVARGDTLTARHLREYVTGTAPATGR"
     misc_feature    19172..19187
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.64"
                     /tool="antismash"
     gene            complement(19373..20086)
                     /locus_tag="LC193_RS15530"
                     /old_locus_tag="LC193_15530"
     CDS             complement(19373..20086)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010057609.1"
                     /locus_tag="LC193_RS15530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15530"
                     /product="hypothetical protein"
                     /protein_id="WP_226074809.1"
                     /transl_table=11
                     /translation="MNAGRARRVAARLLRHELALVAGLSRAVGRRGPHGVGPGDVAVGY
                     AAAQSALMWVALLVSVVETVVLALVVPWPAVHAVLLVIGLWGIWFVAAHQAACAVRPHV
                     VGADGSLRIRYGAFVDIRVPAGRVAAARAELRWAGAGLLRTEGAEDGQGDGQGDGQGDG
                     QGDGQGGGFGAEGGTADLAVAGQTCVTVELTEPVAFSRPLGRPARARVLRFWADDARAA
                     VAALHRARADREGSG"
     gene            complement(20083..20898)
                     /locus_tag="LC193_RS15535"
                     /old_locus_tag="LC193_15535"
     CDS             complement(20083..20898)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018840916.1"
                     /locus_tag="LC193_RS15535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_15535"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_226074811.1"
                     /transl_table=11
                     /translation="MRIGELAALAGVTPRTVRHYHHIGLLPESAREANGYRSYGLRDAV
                     RLGRVRRLTELGLSLDEIRDILTDDTGRELHEVLAELDAELAARQEALGRRRARLAELL
                     REVGTAGDLPAEAPVSPEVAALFASMARTAADLPGPEPHTAVRERELLALLDGSADPAT
                     ADWLAGLLRTADREPDAMRRVYEVYARMDELADADASDPRIPRVAEAIVAVLPEEFADA
                     LAGPSRQALDAAGAGGGGFAEAFFAELPPAQAAAVRQAVLLLAQRDGGR"
     misc_feature    20908..20919
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.29"
                     /tool="antismash"
     misc_feature    21913..21928
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.15"
                     /tool="antismash"
ORIGIN
        1 ccggccgggc aacggaccac gggaggaccg catgaccctg cgctgcctgg tgaccggcgc
       61 cacgggctat ctcggcggcc ggctcgtgcc cgagctgctc gcggccgggc acaccgtccg
      121 ctgcctggcc cgcacgcccg cgcggctgaa cgaccgcccg tgggccgacc gggtcgaggc
      181 cgtgcgcggc gacgtcaccg acccggcctc ggtgcgttcc gcgctcgaag gcatcgaggt
      241 cgcctactac ctggtgcacg cgctcggggg gcgcggcgcg ttcgaggaga tcgaccgcga
      301 ggcggcgcac gtgttcgccg ccgcggcgcg cgacgcgggc gtccgccgcc tggtctacgc
      361 cggggcgctc acgcccgagg gcgttccgga gcgggagctg tcgccgcacc tgaggtcccg
      421 cgccgaggtc gggcacatcc tgctggactc gggcgtgccg acggcggtgc tccgcgccgc
      481 cgtcgtcatc ggctcgggct ccgcgtcgtt cgagatgctg cgccagctcg gggaacgcct
      541 tcccgtcatg gtcaccccgc gctgggtccg cacccgcgtg cagccggtcg ccgtccgcga
      601 catgctgcgg gtcctggccg gcagcgccga gctgcccgcc gacgtcaacc gcgcgttcga
      661 cgtcggcggc cccgacgtgg tgacgtacga gacgatgctg cgccgctacg cggtcagggc
      721 cgggctgcgc aggcggctga tcgttccggt gccggtgctc acgcccggtc tttccagcct
      781 gtgggtcggt ctcgtcaccc cgctgcccgg ccggctggcc cgtccgctgg tggagtcgct
      841 gcgccacgaa gtggtgtgcc gcgaacggga catcgaacgg tacgttcccc cgccgcccgg
      901 cgcaccgctc ggcctggacg ccgcactcga cgcggccctc gacaccacct cgggccccac
      961 ccccgacctc tcccgcgacc gggccagggc gcgggcgcgg gagaggccgg gggagaggcc
     1021 ggggagcagg gaacgcgagc gggagcggga ggtggagtcc gttcccggcg ggtcccggga
     1081 ccgcgccccg gccgacgcgg cggcggggcc gttgccgagc gacccggcgt gggcgggcgg
     1141 cagcctgtac accgaccggc gcgagcgcgc cgtcgacacc tcgcccgagg cgctgtggcg
     1201 cgtcgtcgag gggatcggcg gcgagaacgg ctggtactcc tcgccggtgg cctgggccgt
     1261 gcgcggctgg ctcgacagcc tcgtgggcgg cggcggcctg cgacgcggca ggcgcgacgc
     1321 ggcgcgcctg cgggtcgggg acgcgctcga cttctggcgc gtggaggcgc tcgaacccga
     1381 acgcctgctg cggctgcgcg gcgagatgcg cgtgccgggc accgcgtggc ttgagctgtg
     1441 tgtcgaccgg gacgacgagg gccgcacggt gtaccgtcag cgggccctgt tccacccgcg
     1501 cggcctggcg gggcacgcct actggtgggc ggtggccccg ttccacgcct gggtcttcgg
     1561 gggcatggtc cgcaccatca cgagcaccgc gcaggcggag gggtgagtcc gcgatgagcc
     1621 gggaccgcga acgtgcgcag cacgagggcg ccaagggcgg caggggcggc agtggtgcga
     1681 aacacgacgg cgtgaacggc gcgaacggcg cgcgggccgt gtccgtcgcg ctgttcaccg
     1741 ccgacctgcg cctgcgcgac aacccggtgc tgcacggcgc gctgcgggac gcccccgagg
     1801 tggtgccgct gttcgtcgtc gacgacgggg tgcgcgcggc cgggttccgc gtgcccaacc
     1861 gggcggcgtt cctcgccgac tgcctggccg acctcgacgc cgcgctgcgc gagcgcggcg
     1921 ggcggctcgt cgtcgcgcgc ggcgacgtcg tcgccgagac gtgccgcgtc gcggctgccg
     1981 tcggcgcggc gacggtgcac ctcgccgccg acgtcagcgg ctacgcggcg cgccgcgagg
     2041 agcggctgcg tgccgcgctc gccgccgacg ggcggcggct gaccgtgcac gacgcgacgg
     2101 tcacggccgt gccgcccggc gtgatcgcgc cgcagggcaa ggaccacttc gcggtgttct
     2161 cgccgtactt caggcgctgg gacgccatgt cgctgcgcga cgtgctgcgc gcgccgcgca
     2221 cggtgcgcgt gcccgaggtg cggtccgcgc gcctgcccgc ggcctcggac ctggcgtcgg
     2281 gcacgccgtc accgggcctg cccgagggcg gcgagtccgc ggcgcggcgg cggctgcgcg
     2341 cgtgggagcg cggaccgctg gacgcgtacg ctgaccggca cgacgacctg gcgggggacg
     2401 gcacctcgcg cctctcgccc tacctgcact tcggctgcgt ctccgcgaac gaactcgtgc
     2461 accgctcccg gcggcacggc ggcgcgggcg cggacgcgtt cgtccggcaa ctggcctggc
     2521 gcgacttcca ccaccaggtg ctcgccgccc gcccggacgc cgcgcaccgc gactaccgcg
     2581 accggcggag cgagccgtgg cggaacgccg acgccctcgc ggacgccgtc acggcgtggc
     2641 gcgagggcag gaccggtttc cccatcgtgg acgcggcgat gcggcaactc gcgcacgagg
     2701 gctggatgca caaccgcggc cggctgctcg tggcgagctt cctgaccaag acgctgaacg
     2761 tgcactggcg ggtgggggcg cggcacttcc tcgacctgct cgtggacggc gacctggcga
     2821 acaaccagct caactggcag tgggtggcgg gcacaggcaa cgacacgcgc cccaaccggg
     2881 tgctgaaccc gttgagccag gcccgccgtt tcgacccgcg cggggactac gtgcgccggt
     2941 gggtgccgga gctggccggg gtcgagggcc gggccgtgca ccgcccgtgg cggctggacg
     3001 cggacctcga ctacccggac ccgatcgtcg agccctggtg aggacgcggc tcgggcgagg
     3061 ccgcgacccc ggtgggcccg ggcggcgccg tcgcgctgct ccccccgggt ggtgtcctgg
     3121 cccggcgggc ctcgcggggg gcgtggcggg gcatgtctgc ggttcccgct ttccccacgc
     3181 accgccggag gtacccatgg cgacgggttc gatcatcttc aggtcggccg acggccgaac
     3241 gcaggtcatc gacgagccgg agaacggcgg ccggttcccg ctcggggagg ccgggctgct
     3301 ggagaacaac acggaccgcg aactgcggct catcccgccg gccgggcagg gggaccccgc
     3361 cgtgctccag cccggcggca gcgcgcagat cgaggcgggc tcggccgtcc acgtggtctg
     3421 aggcccggcc gccgaacgcc tgccgcccgc cgccgaacgc ccgccggcta cgccccgggc
     3481 gcgcccgagg ccgcgagcac gtcgtgcccg acgtcctccc ggtcggccgc gtcgagcacc
     3541 gcgtcgagca gcccggggaa ccgggcgtcg aggtcggcgc ggcgcagttc gacgaagcac
     3601 cgcgtgccct cctgcctggt ccgcgtgatg cccgcgtcgc gcagcacccg caggtggtgg
     3661 ctgagcgtgg acttggcgac gggcgcgcgc aggtcgcccc aggcccgttc cgcgccgtcg
     3721 gacagcaggc ggacgagccc gatcctgacc gggtcgctca gcgcggacat cgccgcgatc
     3781 agcgtcatct cgccggtgct cgggtgccgc acatctcgca tggacacgat gatacgttcg
     3841 ttctatgttc gtcgaacatc gaacgaaggg tgacgccttg tcccagcact ccccggcccc
     3901 cggccggttc caccagcgcg tcacgatcgt cacgggcgcg gggtccggca tcggccgggc
     3961 cgccgccctc gccctcgcgg ccgagggggc ccacgtgctc ggcgtcggcc gccggccggg
     4021 accgctggag gagaccgccc gcgcccaccc gggcatcgtc gccttcccgg cggacatccg
     4081 cgcccccggc gccgctgagg cggtcgtcgg cgcggcggtg gaccgctggg gccggatcga
     4141 cgtcctggtc aacaacgcgg gcggcatgga cgccatgacc ctgcccgagg tgacggccga
     4201 gcgggtggcg cggatgttcg acctgaacgt gatcgccccc agcctcctcg cccgcgccgc
     4261 cctgccgcac ctgcgggaga cgcgcggctc gatactcaac gtctccagca tctacggtca
     4321 ccggccgggt gccggggtgt cccactacgc ggcctccaag agcgcgctcg aacagctcac
     4381 gcgctcctgg gcgctcgaac tggccggaga gggcgtccgc gtcaacgccc tggcgccggg
     4441 gccgaccgag agcgaggcgc tgcacgccgc cgggctgccc gaggaggtca tcgcggcggt
     4501 caaggccgag gaggccgccc gcatcccgct cggccggcgc ggcgagccgg aggaggtcgc
     4561 cgcgtggctg ctccacctcg ccgatccggc cgccacgtgg ttcaccggcc aggtcctcgc
     4621 cgtcgacggc gggctcaacc tgacctgacg aacgcccgac ccggcctgaa gaaacgcccg
     4681 acccggcgca cgccgggtca gggcagcacg atgcgctcga cggcggcctg caccaggcgt
     4741 tcgcgctcgt cctcggagta caggtccggc agcgtgagct gttcgaggat gagccagttc
     4801 agcgtcagca tcaggagccg gacggcggtc gcgtcccccg gcagcccgga tgcctcgtgg
     4861 tacgcgacgt tggcgtcggc gtccgcgcgg acgcgcgcgg tgaggacctc gcgcaggcgc
     4921 gggcgccggg tcgcctccag gcgcagttcg agcagggcca ggtagccggt gcggaacgcg
     4981 ctgacgcggc cgaccagttc gcgcatcagc gtcacgtacg tgtcccggtc gcgcggcgcg
     5041 tcccgcaggc gggccaccgc ggcctcgtcc ggctggaggc gttcgtagaa gcgctcgccc
     5101 acctgcgtga acagctcgtc gcggttggcg aagtagttcg aggccgtgcc cttcggcacc
     5161 ccggcgccgg cgtcgacggc gcggaaggtg aggccgcgcg ccccttcctg cgccagtacc
     5221 tcgatcgcgg cgtccagcag cgccgcccgc cgttcgtcgt tccgccgcac cattgacacc
     5281 actccagttg tagtactacg ttctcaccgg tcacagacta ctatgcttgg agtggtttta
     5341 tgcgaaagct cgtctactac atcgccgtca ccctcgacgg ccgcatcgcc ggacccggcg
     5401 gcgagtacga cttcttcccg ctcgggaacg aggagcaggc cgccggctac gcggagcgga
     5461 tgaacgcgcg ctatcccgag ttcctgccga ccgccgggcg ggagatgttc ggcctggccg
     5521 acgtccccaa ccgccgctgc gacacggtcg tgatgggccg cggcgcctac ctgcccgggc
     5581 tggacgcggg catgaccagt ccctacgccc acatgcggca gtacgtcgtc tcccgcaccc
     5641 tcgacgtcgg catcgacccg gacgtcaccg tggtcccctc cgatccgctc ggcctcgtcc
     5701 gccggctcaa acaggaggac ggcggcctgg acatctggct ctgcggcggc ggccggctcg
     5761 ccggggaact gctcccggag atcgacgagt tgatcatcaa gagctacccg gtcgtcgccg
     5821 gggccgggcc ctcggtgttc gacggggcgt tcgatcccac gctgttcacg cccaccgcac
     5881 gcgagacgtt cgacaacggc gtgctggtca cctggtgcac ggcccgctga cgcccggcgc
     5941 ccgccggacg cgcggcgtcc ggcaggcgcc gggcgggtgc ggcgggcgcc ccgtcagggc
     6001 ctgcgcgcct cgatgaggaa gcgctgcgcg tgcgcgacga acgggccgtg ccgttcgatg
     6061 aagtcgtgca gctccacgag gcgttcccgg taggcgtccg cggtgaagcc cggcacggtc
     6121 cagatcacct tgcgcaggaa gtgcacgacg gccgcgatgt cgtggaactc catgcgcaac
     6181 gcctgctgcc gcacgtccac gacgacgagc cccgccgact ccgcgacggc cacggcgccc
     6241 gtcggcgtcg cgcccgacct ggtcgtgaac ggccgggccg gcgggggcgg cgggaagggg
     6301 ttctgcccca tcatgaactc cgtcaactcc cgcacgctgc ccgcccccac gtgctgcgcc
     6361 aggtaggtgc cgcccggccg cagcacccgg cgcacctcgt cccaccgcgt caccaccggg
     6421 tgccggctga ccaccaggtc gaagtgcccg tcggggaacg gcagatccgc cgcgtcgtcc
     6481 gtcatggcga cgacggtcgc cccgaagggg gccaggttcc ggcgggcgat ccccacgttc
     6541 ggcggccacg actccgtggc cgcgagcacg ggcggcagca cgggaacggc ggccagtacc
     6601 tcgccgccgc ccgtctgcat gtcgagcgcc gcctccgccg cccgcatccg gtccgcgagc
     6661 agcgacgagt acccccaggc cgggcgttcc tccgtggccc gcccggcgaa ccacgagaag
     6721 tcccagccct ccgtcggaac ggcctcgccc tcggcgacga gttcatcgaa cgtggctgct
     6781 atcccgggag acatgaggtt cccggggctc ccggggcttg cggtgcgcat gcggcgagga
     6841 tcgcagaccg ccggcggcca cgcaccagaa ttcgccgcct tcccgagggg ccgtgacgac
     6901 gcccggcgcc ccggggcgga cccgaacgaa cccgaacgaa cccgaacggg ccgaacggac
     6961 gcggcgcgcg gcccgttcgg cccgggggcg cggcggggcc gttcaccgcg cgccgcgcgg
     7021 atcagcgcag cgtgcggatc agcgtctcgg cccggtgggt gagcgccgcg cgggccgggt
     7081 ccgcaacgcc gcgcaggtgt tcgagcgtcg cggtgaaccg ttcaagcgcc ctcgccgccg
     7141 aggcgtggtc gccgcgcgcc atgtgcagct cggccttcac cgtccacggc ttcagcagca
     7201 gcgcggagag gaacgacacc tcgccgcccg ccacgcgccc ggccaggtcg tcggccagcg
     7261 cggccacccc gcccggggtc cacaggtcgg gcaccggcac ggcggagaag tccatgtccg
     7321 aggccaggta gaagccggtg taggacggct ggttgtacgt cgtctgctgc cgcgccacct
     7381 cggcccggta ctgcgggtcg tgcatcaggg tgtacagctt gtggccggtg agttcggtgc
     7441 tgaggtacag ccgcaggccg gtgctgtccg ccgtgggcac gagcagctcc tcgcgccagt
     7501 cgcccaggac gtcggcgacc agggacggat tgcccttggt gtggttgttc gtcctggtgc
     7561 cctcggccgt gagcagcgtg ccgcgccgcc agtcctcgac gaccgtgtcc tcgccgagat
     7621 acccgtaccc ggccaccatc tgggccgtca ggtcgcccgc ccagcggatg ctctggttcg
     7681 tgccgggcgt ccgctccccg agccgccggc cgtccgcgct ccacaggccg acgccgtcgg
     7741 ggtcggtgcc gccctcgggg tggttggccc acgtctcgat cccgggctcg tccgggtcga
     7801 cgtccccgat catgccgcgt ccggtgtcga cgccggtgta ctcgccgtag atgacctcgc
     7861 cggtcgcggc gtcgcgcagc gcgtagccga gcggcgcgct cgcgccgccc tcgtgcacgg
     7921 tgtagatctc cagtccagga cgcgccgggt cgatgtcggt gacgtgcatc gcgtcgccgt
     7981 ggccgaggcg ggcctgcgcg ccggggtcgg cgctgccggg cggcatctcg gcgaacgagc
     8041 tgtacagcag gctgccgtcg tcgtcgatgg tcgcggaccc gtagacgacc tcctgccggc
     8101 cgtcgccgtc gacgtcggcc gcgctcagcg agtggaagcc ctgcgtggtc agcgtgccga
     8161 actcggggtc ggtgccgtcg acgccgtgcg ggccgtcgtt gaacgggttg gacatcgggg
     8221 tccagccgct gtcgacgttc cagtcctcgc gcagcctgtg cccgtcccag cggtaggaca
     8281 ccagcgtgga gcgcgtgtag tagccgcgcg cgaacacggc cgaggggtgc tgcccgtcga
     8341 cgtaggcgac ggtggacagg aagcggtcca cgcggttgcc cggctcgatg cgggccatgg
     8401 cgtagtcgcc ccacatcagg ccgtcgtcgt ggcggcccgg ctcgtagcgg accgtgtcga
     8461 gctcgcggcc ggtcgcgccg tcgaacacgc tgaggtattc gggcccttcg aggatgaagc
     8521 cctcgaacgc gcgcaggttg ttgcgcgcgc tgcgggaggg cgcgtactcg tccatgaagt
     8581 ggtcggccag cgcctcggcg tcctcgcggg acagggggta gtcgtgggcg ggcgcgatgc
     8641 cgaacgcctc ctcaagcgtc gcgggccagt tgcccgccac gacctcgggg tgctcgtgcc
     8701 agtcctcgaa catgccgacg acgtgcgcgt agtagtcctc ggcactcatc cggtagtcgt
     8761 cgtcgtgccc gtatcccgcg cggatgtcct cgcgcggcat ggtgatgtgg cgctccgagg
     8821 cgacacggcc gtccgggtgg tagcgggtga ccttggtgcc cggcgcggtc ttgaacatga
     8881 tctccgagcg gccgtcgccg tcgaagtcgt gcacgaggaa ctgggtgtag tgggctccgg
     8941 cgcggatgtt cacgccgagg tcgacgcggt gcagcagggt gccgtcgagg cggtaggtgt
     9001 cgaggtagac gttgccggtg tagccgacct gggagacgtc cttggcgttc gacgggtacc
     9061 acttgacgac gtactcgtac tggccgtcgc cgtccacgtc gccgacgctg acgtcgttcg
     9121 ccgagtaggt gtacgcctcg ccggccgggg tgacgccgtc ggccggcttg tccagcggca
     9181 gttcgtagta gccgtcggac cagggggcga cgggctcgct gaggtcgacc tcgacgccgt
     9241 cgacgacggc ggccacgcgg tactcggcgc ccgcgggcgc ttcggcgtcg aggtagttgg
     9301 tcgattctgt gacggtgccg agcagttcgc cgtcgcggta cacgtggaag tcggcgccgg
     9361 tcaggccggt ttccgagtgc ccggtgacct cggtggccag cagccgccag ctgaggaaca
     9421 cgccctcctc ggtggcgacg gcggccagac cgcggtcgag gtgttcgagc tggacgccgc
     9481 cgggcgcggg gcgctcggtg ccgcgcgcgg ccggttgcgc ggccggttcc gccgcccgcg
     9541 cgggggcggt gcccgccgcg gcgagcaggc ccgcggtcat caggccggcg agcggggcgg
     9601 cgatcaaccg ccggtgcctg gccctacgtc gtctgtccgc tggtgtcatc gggtgacgcc
     9661 cttcttgcct gtcgcgcgtt gagccttcgg cctgccgcgc gaggccggtc gtgaggtgct
     9721 tgatgggtgc ggtggcgcgc tggacgggcg cgtggaaagg ggacgagagc ggattgagtc
     9781 gtttcaatga gacgtttcaa aacgggtcgg cgcgacagta tgagggggcg ggtccgccgt
     9841 caagagttcg cgtcggtacg cagcgcgacc gcgcacgcgt cgcatggttc actcgaaccg
     9901 gcgaattgag gtgcgaattg ttctgattgt cctgcggtgg gccggagcac gggcaatgct
     9961 gtgggccatt cgggtgccac gcgatgccgg gagacgcgcc atgacacagc ccttcgaact
    10021 gcccgcgttc tacatgccgt atcccgcgcg gctcaacccc cacctcgacg cggccaggga
    10081 gcactcgccg cgctgggccg cacgcatggg gatgctggag ggctccggga tctggaccgg
    10141 cgccgacctc gacgcgcacg actacccgct gctgtgcgcg tacacgcacc cggacgcctc
    10201 ggccgaggac ctgtgcctgg tcaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttccttgag accttcaagc gcacccagga ccggccgggc ggcaaggcgt acctcgaccg
    10321 gctgcccgcg ttcatgccgc tcgacccggc cgcgggcacc cccgagccga cgaacccggt
    10381 ggaggccggg ctcgccgatc tgtgggccag gacggtgcct gccatgtcgg ccgcgtggcg
    10441 gcgcaggttc gccgagagca ccgccaacct gctgaacgag tcgctgtggg agctgtccaa
    10501 catcaacgcc ggccgcgtgc ccaaccccgt cgagtacatc gagatgcgcc gcaaggtcgg
    10561 cggcgcgccc tggtcggcgg gtctcgtcga gtacgcggcg cgcgccgagg tgccggcggc
    10621 cgtcgcggcg agccggccgc tgcgcgtgct gcgcgacacc ttctccgacg gcgtccacct
    10681 gcgcaacgac ctgttctcct accagcggga gatcgaggac gagggcgaga tgagcaacgg
    10741 cgtcctcgtg ctggagacgt tcctcgcgtg ctcgacgcag gaggccgccg aggccgtcaa
    10801 cgacctgctg accgcgcgcc tccagcagtt cgagcacacc tgcgtgaccg aactgggccc
    10861 gctgttcgcg gagtccgggc tcgacgccgc gtcctgcgcc gcggtcctcg cctatgccaa
    10921 gggacttcag gactggcagt cgggcggcca cgagtggcac atgcgctcca gccggtacat
    10981 gaacggagcg gtcggcggtg gcgcggcgca cgcgcacgcg cccgcgcccg gcctcgctgc
    11041 gctgccgacg ctgcccgggc tgccgccagg actcggcacc gcggccctcc gcgcgccggg
    11101 cggcgcgcgg cgcggccccg gcggcgtgac gaccacccgc agggcggagg cggccagggc
    11161 caggcggttc cggcacgtgc cgcaccggcg cgtcgggccc tcgctgctgc cggacttccc
    11221 catgccgttc gacctgcggc tcaacgtgca cctcgacggc gcgcggacgc gcctggccgc
    11281 gtgggcgcac cgggtcggca tcctcgacgg tgcgccgtgg accgaggcca agctgtacga
    11341 ctacgacctg ccgctgtgcg ccgcggggct tgcccccgac gcaccggccg acgcgctcga
    11401 cgtggtctcc ggctggctgg catggggcac ctacggcgac gacctgtacc cggtcctctt
    11461 cggccgcacc cacgacgtgg cgggcgcgcg ggccgtgacc gagcggatcg cgcagttcat
    11521 gcccgtcgag gacccgaacg cgatgccggt cccggtgtca gggctggaac gcggcctcgc
    11581 ggacctgtgg ccgcgcaccg cggggccgat gacgctgccc gcgcggcgca ggttccgcga
    11641 gacgatcgag gtgatgacgg cgagctgggt ctgggagctg gacaaccagg cgcagaaccg
    11701 cattcccgag cccgtcgact acgtcgagat gcgccggcag acgttcggct ccgacctgac
    11761 gatgtgcctg gccaggctcg ggcacggccc gaaggtgccg caggaggtct accgcagcgg
    11821 tccgatcagc tcactggaga acgcggcggc cgactacgcc tgcctgatga acgacgtgtt
    11881 ctcgtaccag aaggagatcg agttcgaggg ggagatccac aatggtgtgc tggtggtgca
    11941 ggacttcttc gactgcgact acccggcggc gctgcgcgtg atcgcggacc tgatggccga
    12001 gcgcatgcgg cagttccagc acgtcgcggc gcatgagcta ccggtcttgt acgaggactt
    12061 cgggctcgac gacgaggtgc ggggcatcct cgacgggtac gtccgcgacc tggagaactg
    12121 gctggccggc atcctgaact ggcaccggtt ctgccgccgg taccgcgaga gcgacctgcg
    12181 caggcacgcg cagggcgcgt tgtggccgct gggcgcgccg acgggcctcg gcacctcggc
    12241 ggccaggatc acccggctgc tcggcccgcc cgcggcgcgc cgggcgtcgt aggcgggatc
    12301 ggtcgggctg ggcgcgttgg acgggttgga cgggttggtc gtatcgctcg tgtcgggcgc
    12361 gttggtcatg ccggtcgtat cggccgtgcc ggtcctttcc gccacgggtc ggcggtgatg
    12421 ccgcggccgg tcaatggacg atggacacga tccggcaggc agccgccgcc agttcgcggt
    12481 cgccgtgcag gcgggccagg gtgagggcgt cgtccggtgc gatgccgcgg gtgcacaggc
    12541 gccaggcggt ctccgggtcc aactcgacgg tcgcggcggg gtgttcgccc gcgggcgggg
    12601 cgagcgacca gcgctcgccc gtcgcggtgg cggtccacgt gccgccggcc gggccgtcga
    12661 tccgcacgcg gagctgggtg ccgaccggcg cgtcgaccgc gcgcagcgtg tgcggaaggg
    12721 cgcgcatgaa ggtgtcgagg accacggacc acagccgtgg gtcggggtcg gtgccccgcc
    12781 cggcggcgtg ccggatctgc tggcggtgcg tccagaactc ggtgagttca cgggcgctgt
    12841 ccagccacat cggtgccggg tcggctcccg cccaggacac gccgagcgac ggggagtcgg
    12901 ggtcggtggc ctcgaagtac cggacggtct gcccgcccac caggtccagg gtgtcggtga
    12961 gcgcggccgg gctcacccgg gcgaacgcgg ccacccactc cgcgttggcg cggtggatga
    13021 acgcctcaag cgcctcgccc ggcgcgggtg acggccctcc ccggtgtccg tcgcgggcgc
    13081 gggcgagtcg cccgtagcag tcgcccagaa tgtgggcggc gagatcccgc acggtccagc
    13141 ccggcaccgc ttccctgccc cagtcgaccg gcgcgaggtc gcgcagcagc gccatcaacg
    13201 cggcgtgctc gggggcgaac agcggccggg cgtcgatcgg ggcaccgagc caggcgtgac
    13261 cggctccgcc gcctcgcgag gtgtccatga ccgcagtctg ccgccccgcg cacccggcgg
    13321 ccaccgctta tgcggtccgg gcaccggaac ccggcaccgc aggcatcgcg gcggccgtcc
    13381 ggccgttgag gcgccgggcc gtgtcgggcc gtccggccgt tgaggcgccg accgttgcgc
    13441 tgccgggccg gtccatccga ccgttgcgct gccgggccgt cgcgctgccg ggccgggccg
    13501 aggcgtcagc gggccgcggc ccggcgggcg ttcggactct cgggcagcag cagaccggcg
    13561 agcgtgagcg cgccccaccc cacggacacc gcgaccgcgc cgccgcgccg cgccgggccc
    13621 ggcagcgtcg cgcccagcag gacggcgtcg ccgaagtccg cggccagccg caccgccgcg
    13681 gccgtgcgca gcgccgcgcc ccggggcgcg agcgccagcg cgagcccgca cgcggcctcg
    13741 cgcagcccca ggggccgcag cgacgtgcgc acctcggcgg cggtccgccc gtcgggaccc
    13801 gcgagcccgg acggtttcgc gagcaggccg ggccggaccg tcaccgccac cccgtacgcc
    13861 gtcgtcgcca cacccacggc tcgcagcaca ctcgtacgca tgggtcaact gtgccgcacg
    13921 cccgccccgg cggcaccacg ggaggcgggc ggcccgttca gtccacgggg accacttgga
    13981 gcagcttgtt cgggctgcct gccggtacgc cggtcagcct gccgacggcc gccgcctggt
    14041 cgatggcctg ccccacctgg gcgggcgacg cactcgggtg gtcgcccagg tacagcaccg
    14101 cgacgcccgc ggtgaacgcg gcggaccccg acgttcccga gagcacggcc gtgccgttcg
    14161 gccaggtcga ggcgatgccg acgcccggcg cgaacaggtc cacgaccggg ccgtggttgg
    14221 tgaaccccgc cacccggtcc cggcagtcgg acgccgccgc ggtgatggcc tcggtgacgc
    14281 ggccggggga gtagcggccg gcgtcgtcac cgctgccgcc cgcggcgatc gcgtaggtga
    14341 cgcccgaggc gatggacgtg cgcaccgcct ggtcgagcac ctggctggcc acgccgccga
    14401 gggtcacgag cgcgacggcg ggttcgccct gcgcgtccgc ggtgagccag ttgatgcccg
    14461 cgaccacacc ggcgacggtg cccgagcccg cgtcgttgag caccttgacg gacacgaggt
    14521 cggcctcctt ggcgacgccg tggttcgtgc cgccgacgag gccggccgcc caggtgccgt
    14581 ggccgttgcc gtccgagccg ttgcccccgg tggcgtcgta ccccggaccg gcccggccgc
    14641 cgaagtcggc gtggccgtag gcgatgccgg tgtcgacgat gtaggcggtg gcaccggcgc
    14701 cggccgagtc cggataggtg aaggagccgt cgagcggcag gtccggctgg tcgatgcggt
    14761 cgagtccgca gttgggcggg ttcggctgcg tgccggccgg cagggcgcgg atcacgctgt
    14821 cctgcttgac agcgcggacg gccgggtcgg cggccagccg ccgggcctgc ggcgcggtgg
    14881 cgtggacgtg gaggccggtg agcgcggcgt cgtaggcgtc gacgacgcgc acgccgtagc
    14941 ggtcggccag ccgggcgccc gcctcggcgg ccggttcgcc gccgtcggcg agcaggacca
    15001 ggtagctgcc gtcgaccgcg tcccgtccgg gcgcgccgag gacgtgtccc tcgggggcgg
    15061 ccccggtcgg ggcgggcagg gcggcggcgg tggccgggag cagcagggcg gcggtgagaa
    15121 cggctaccgt gcgggacctg ccggatccgc gcggcacggg ggacgcgccg ggtctgcgga
    15181 ccgtgcgaaa tctgcggagg gtgcggggtc tgcggggcaa gagggctcct cggaacgggc
    15241 ccgggcgacc gggggacggc gtcggatggt tgtgcccatg acaatcacaa ggctgcccgg
    15301 cgtcccttcg ggcggcaaga ccgccggggg cggcccgggg cgcgccccgg gccgccccgg
    15361 accggcgacc gcgcatcaca cggcgccctc gtgcccgcga gcgtcctccc gctccgcgag
    15421 gccggcggca cggccggccg caccggtgcc gcggcctccg gcgtgggcgg cgatgccgtc
    15481 gaggatggtt tcgagcccga gcaggaacga cccgtcgaag tcgtcgtcga cgagccgcgc
    15541 gtgcccggcg agcgtgggat agcggtcctc ccgctgctcg atgaactgct gggcaccggc
    15601 tcgaagttcg gcctcgtcct gcggatcgcg ccggtggacg cgccagacgt tctccgccgc
    15661 ggtgtacccc tggacgaagt acgtcagggc cccgacggcg acggtgagcc gcgccccgtc
    15721 gagcccggcc cgcagcagta gggagtggac gtgttcggag cgcgcgagca cagcgagctg
    15781 gccgcccacc tctcccgttg ggccctgctg tccgatgacg agaccggcgc ggcgctcggc
    15841 accctgcggg ccacgggcat ggccctgtat gttctgggct acttccacgg ctggcggctg
    15901 ctcgactcct ggctcgccac cgcggaccgc gacgttcgcg tacgccgcct gctcaccgag
    15961 caactgcttc cggcggacgt gcggccggcc ggctgaccgg ccgggccgcc gggcgatcgc
    16021 gcggtggcac gggacgggcg agtgaaggga agggacggac gtggggcgcg acgacgagcg
    16081 ggacgtgctg gaccgcatcg ggcgcgggct ggtctacacc gagtccgagg cggtgttcct
    16141 ggacgagcgg cgcagggccg acctcatctt cgcgtacaac cacaccccgc cgggcgacac
    16201 ccgcaagcgg cgctcactgc tccgcgcgat cctcggatcc gtcggtgaac gccccgcgct
    16261 gcacccgccg ttcagcgcgg ccttcggcag caacgtccac atcggcgacg acttcttcgg
    16321 caacgtcaat ctcgccttcg tggacgacgt cgagattcgc atcggccacg gggtcatgac
    16381 cgcccccagc gtgacgctca ccacgaccgg gcaccccgtc cacccggcgc gccgggtcga
    16441 cttcgcgcgg ttctccgaac cgatcgtcat cgaggacaag gtgtggatcg gcagcaacgt
    16501 cgtggtcctg cccggcgtcc gcatcggata cggctcggtc atcggcgccg gcagtgtcgt
    16561 cgccaaggac gtgccgccca tggtggtcgc ggtcggtacg ccgtgccggg tcctccgcga
    16621 catcacggac gacgacctga cgacgcgaac ggcagccgcc gatcggtgac cgccgggccg
    16681 gcccgaacgt ccgttccccc cgcggggctt tccgggccgc gcccggccgg cccgccccgg
    16741 gcgccccggc gcgcccgggc cgggccgcag ccgctcaccg gccggtcgcg ggcgccgttc
    16801 ccgtgacgta ctcgcgcagg tgccgcgcgg tgagcgtgtc gccccgcgcc accagctcgg
    16861 ccggcgtgcc ggtgaacacc acctgcccgc cgtcgtgccc cgcgcccggg cccatgtcga
    16921 tcagccagtc ggcgtgcgcc atgaccgcct ggtggtgctc gatgacgatc actgtgttcc
    16981 ctgcgtccac cagccggtcg agcagcgcga gcagctggtc gacgtcggcc aggtgcaagc
    17041 cggtggtcgg ctcgtccagc acgtacgtcg ccgccttctc cgccatgtgg atggccagct
    17101 tcagccgctg ccgctcgccg cccgacaggg tcgtcagcgg ctggccgagc cgcacgtagc
    17161 cgagccccac gtccatcagg cggctcagga tggcctgcgc ctgcccggtg cggaagaact
    17221 tgtgcgcctc cgccacgggc atctcaagca cctcgctgat gtccttgccg tcgagcgtgt
    17281 acgtcagcac ctcgggcgtg aaccgcttgc cctcgcactc ctcgcacacc gaggccaccc
    17341 cggccatcat cgccaggtcg gtgtagacga gcccgatccc gttgcagttg gcgcaggccc
    17401 ccgccgaatt ggcgctgaac agcgccggct tcacgccgtt ggccttggcg aacgccttgc
    17461 ggatcgggtc gaggagcccg gtgtacgtcg ccgggttgct gcgccgcgag ccccggatgg
    17521 cggactggtc ggccaccacg acgccggccc ggcccggcag ggcgccgtgg atgagggagc
    17581 tcttgccgga gcctgcgacg cccgtgacga ccgtcagcac gccgacgggt atgtcgacgt
    17641 ccacgttccg caggttgtgc gtggcggccc cggtgatcga caggtgcccg cgcggggtgc
    17701 gcaccgtctc gcgcagcgcc gcccggtgcg cgaggtgcct gccggtcctg gtgcccgacg
    17761 cgcgcagccc ggccacgtcc cccgcgtagc agatctcgcc gcccgaggtg ccggcgccgg
    17821 ggccgaggtc gacgacgtgg tcggcgatgg cgacgacctc gggcttgtgc tcgacgacca
    17881 gcaccgtgtt gcccttgtcg cgcagccgca gcagcaggtc gttcatccgc tggatgtcgt
    17941 gcgggtgcag accggtggtg ggctcgtcga acacgtaggt cacgtccgtg aggctggaac
    18001 cgaggtggcg gaccatcttc acgcgctgcg actcgccgcc cgacagcgtg ccggacggcc
    18061 ggtcgagcga gaggtagccg agcccgatct ccaccagcga gccgagcagg tcgcgcagcg
    18121 cgccgagcat gggcgcgacc gagggcgcgt cgaggccgcg gacgaactcg gccaggtcgc
    18181 tgatctgcat cgcggagcac tccgcgatgt tcaccccgtt gatcgtggag gacagcgcgg
    18241 cggcgctcag ccgcgtgccc cggcaggtcg ggcacgcggc gaagacgacc gcccggtcca
    18301 cgaacgcgcg cagcgtcgtc tgcatcgtct cccggtcctt ggacaggtag acgcggttca
    18361 ccttcgtgac caggccctcg taggtgatgg tgttcgtccc ggccttgatc ttcgtggccg
    18421 gcttgtgcag gaagtcctcc cacagctcgg ccgggtagtc cttcagcttc atgtcgttgt
    18481 cgaacaggcc cgaggcggcc atgacctgcc agtaccaggt gccgaccccg aagcccggca
    18541 cggtgatcgc gccctcgttg agcgacagtt cgcggtccac cagctgatcg atgtcaatgc
    18601 gcgagacctg gcccatgccc tcgcagtcct ggcacgcgcc ctcggggctg ttgaagctga
    18661 acgcggtcga ggtcccgatg tgcggcgtgc cgaggcggct gtagacgatc cgcagcatcg
    18721 tgtaggcgtc cgtgaccgtg cccacggtgg accgcgagtt ggcccccatc cgctcctggt
    18781 cgacgacgat ggcggcgctc aggttgtgca gcgcgtcgac gtcggggcgg ccgaggctgg
    18841 gcatgaagcc ctgcacgaag gcgctgtacg tctcgttgat cagccgctgc gactcggccg
    18901 cgatcgtgcc gaagaccagg gacgacttgc cggagcccga gacgcccgtg aagacggtca
    18961 gccgccgctt gggtatgtcg agggagacgt cccgcagatt gttctcccgg gcgccgcgca
    19021 ccttgatcac gtcgtggctg tccgccgcca ccgggccggc cgcggcctcc ggcgggtgcg
    19081 cggcctggcc gcgcggcggt gcggcgggct gctggaacgg gtcggcgggc atgcgtttct
    19141 ccctcgtgcg gaacggtgcg gaacggtgtc gaacggtgtg gaccagtgcg gacggccggg
    19201 ggcggcgaac gcggccgggc ccacgagccc ggaccgctcg atcatggcac ccgccactga
    19261 caacgccagg agcgccgatg cccccgggac ggacaccgtg cacgagtccc gcaccgttgt
    19321 cgaccgcgtt tcccgtccgg cgcccggcct gcggcgtgcg gcccggccgc cgtcagcccg
    19381 acccctcccg gtccgcccgc gcacggtgca gcgcggccac ggccgcgcgg gcgtcgtcgg
    19441 cccagaaccg cagcacccgg gcccgcgccg gccgccccag gggccgcgaa aaggcgaccg
    19501 gctcggtgag ttcgacggtc acgcaggtct gccccgcgac cgccaggtcc gccgttcccc
    19561 cctcggcgcc gaagccaccg ccctggccgt ctccctggcc gtctccctgg ccgtctccct
    19621 ggccgtctcc ctggccgtcc tccgcgccct cggtccgcag cagcccggcc ccggcccagc
    19681 ggagctcggc gcgcgccgcg gcgacgcggc ccgcgggcac ccggatgtcg acgaacgcgc
    19741 cgtaccgtat ccgcagcgag ccgtcggcgc cgaccacgtg cggccggacc gcgcacgcgg
    19801 cctggtgcgc cgcgacgaac cagatccccc acaggccgat caccagcagc acggcgtgca
    19861 ccgcgggcca cgggacgacg agcgcgagca ccaccgtttc gacgaccgag accagcagcg
    19921 ccacccacat cagcgccgac tgcgccgccg cgtaccccac ggcgacgtcg cccggcccca
    19981 cgccgtgcgg gccgcggcgg ccgaccgccc gcgacagccc ggccaccagc gccagttcgt
    20041 gccgcagcag ccgcgcggcc acccgccggg cgcggcccgc gttcaccggc cgccgtcccg
    20101 ctgtgcgagc agcaggaccg cctgccggac ggccgccgcc tgcgcgggcg gcaactcggc
    20161 gaagaacgcc tcggcgaacc cgccgccgcc cgcgcccgcc gcgtcgagcg cctgccgcga
    20221 cggcccggcg agcgcgtccg cgaactcctc gggcagcacg gccacgatgg cctcggccac
    20281 gcgcgggatg cgcgggtccg acgcgtcggc gtccgccagc tcgtccatgc gcgcgtacac
    20341 ctcgtagacg cgccgcatcg cgtccggctc gcggtcggcc gtcctcagca gcccggccag
    20401 ccagtcggcg gtcgcggggt cggccgaacc gtcgagcagc gcgagcagtt cgcgttcccg
    20461 cacggccgtg tgcggctcgg ggcccgggag gtcggccgcg gtgcgggcca tcgacgcgaa
    20521 gagcgcggcg acctcaggcg acaccggggc ctcggcgggc aggtcgcccg cggtcccgac
    20581 ctcgcgcagc agctcggcca ggcgggctcg gcggcgcccg agcgcttcct gccgcgcggc
    20641 cagttccgcg tccagctcgg ccaggacctc gtgcagttcg cgcccggtgt cgtcggtgag
    20701 gatgtcgcgg atctcatcga gggacagccc gagttccgtc agccgccgga cgcggccgag
    20761 gcggacggcg tcgcgcaggc cgtaggagcg gtagccgttc gcctcgcggg cggactcggg
    20821 cagcagcccg atgtggtggt agtgccgcac ggtgcggggg gtgacaccgg ccagcgcggc
    20881 gagttctccg atacgcatac ggccagtgaa aacgttgccg ccgcgacaag gtcaagcgaa
    20941 cggccccgcc gccctcggag ttccgccccc gccgccctcg gagatccggc gcccgcccgt
    21001 cacaggctgg gcccccgccg ccggcccagc agctcggcca ggccgagccg ggtggcggcc
    21061 accacgaccc ggtcctcggg ccgcagcacg tacccggggt gcgggtccca cagcaggccg
    21121 gccgcgtcgg cgttcgcctc gcgcgggcgc ggcgccgcca ggtcggggtg ccggtccgcg
    21181 ggctccgccg tgtcgagggc gacgatccgc caggcgcccg cccggtacgc ctcggccacc
    21241 gtccggcccg cgaaccgcgg cagcccggcc acgtcgaggg ccgcgaacag cagcacccgc
    21301 cgttccaccg gcaccgctcc gaggatctgc cggcccatca tcgcgccggc gaacgcgggc
    21361 gccgccagcg tcgacacgct gcggctgcgc gtcagcgcgc cggggtgcgc cgcgcgcagc
    21421 gtgcggtaca cggcggtcgc gaagtcgtcg tcgtagatgc gcaacgacac ccgcaggtcc
    21481 ggctgcacgc ttcgcgcgca cagcgccgcc tccaggttgg tcgcgtccga gctggtcacc
    21541 gcgagcagcg cggaggcgcg ttcgatcttc gcggattcga gcacgccttc ctgcgtgacg
    21601 tcgccgagca ccacgggcac cccgagccgc cgcgccagcg gcacgccgcg cgcctccggg
    21661 tcctcctcca cgcacaccac cgggatgtcc aggtcgcgca gttgggcgag cacccgtgtc
    21721 ccgatcttcc cgagcccgag cagcaccacg tgcccggaca ggccgcgcgg cgggcggcgc
    21781 agcgcggtcg cgccgcggaa cgtgccgagc gcctggagcg cgcccgccac caggatcggc
    21841 agcagcgcga gccccacgag gccggagacc aactggatcg tctgccgcgc caccggttcc
    21901 ccgatggccg gctccccgat ggcgaacagg tcgagcagcg tcaagtaccc ggcccgcaac
    21961 gggtggtcgt ccgtcgccgc ccacagcgcg acggccagcg cgcacaccgc cgcggccacc
    22021 gcggccagcg cccaccgcag ccgcaccgtg aacacctcgg cgagcggcgc gccccgccgc
    22081 gccaggcggc gcgggggcag cggcggcccg gtgtgcgcga tggtctcaag cacgacggtg
    22141 ccgcggcccg tggccgccgc caccgccgcg tcgtcgggca gcagcagcgg cgccgccgcg
    22201 ccgctgcggt cggagccctc ggtgcccgcc gggtcctgcg ccgtcgcaga gagcagcgcc
    22261 agcgtgcaca ggcccgggtc ggcgatctcg cc
//
