LOCUS       NZ_CP084541            21242 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces marincola strain SCSIO 64649 chromosome, complete
            genome.
ACCESSION   NZ_CP084541
VERSION     NZ_CP084541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Strepomyces indimicinicus sp. nov., an antibiotic producing
            actinomycetes isolated from the marine environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Sciences, 164 Xingang West Road, guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. V6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 444.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020410765.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,763
            CDSs (total)                      :: 5,689
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 74
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 21 of 77
            Pseudo Genes (incomplete)         :: 60 of 77
            Pseudo Genes (internal stop)      :: 2 of 77
            Pseudo Genes (multiple problems)  :: 6 of 77
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:57:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3081504
            Orig. end                         :: 3102746
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21242
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="18"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21242
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21242
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11242](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11242)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    1299..1314
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.19"
                     /tool="antismash"
     gene            complement(2025..2492)
                     /locus_tag="LC193_RS13140"
                     /old_locus_tag="LC193_13140"
     CDS             complement(2025..2492)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS13140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_13140"
                     /product="hypothetical protein"
                     /protein_id="WP_226074240.1"
                     /transl_table=11
                     /translation="MRRPHRLAPVAALVAVAALGGCLTVEPEERPGKPVAPAATDAPRT
                     VPPEGGDADEPPSGHAVPSAERPAAGTPGADPEPGAPTGEAPRSSPRAQPPAPPPAARP
                     PEPAPEPEPNPAPEPEPQPEPPPAPEPQPEPPPPSPTAEPAPSEPPPEDGS"
     gene            complement(2672..3034)
                     /locus_tag="LC193_RS13145"
                     /old_locus_tag="LC193_13145"
     CDS             complement(2672..3034)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018566395.1"
                     /locus_tag="LC193_RS13145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13145"
                     /product="metallopeptidase family protein"
                     /protein_id="WP_218027914.1"
                     /transl_table=11
                     /translation="MLEMTREEFEELVSEALDRVPPELTRLMDNVAVFVEDEPPPEDPE
                     LLGLYEGTPLTERGEWYAGVLPDRISIYMGPTLRLCRREGGDRELVVQEVEITVVHEIA
                     HHFGIDDERLHALGYG"
     misc_feature    3054..3065
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.1"
                     /tool="antismash"
     tRNA            3112..3184
                     /anticodon=(pos:3084650..3084652,aa:Glu,seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LC193_RS13150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="LC193_13150"
                     /product="tRNA-Glu"
     gene            3112..3184
                     /locus_tag="LC193_RS13150"
                     /old_locus_tag="LC193_13150"
     misc_feature    3169..3184
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.07"
                     /tool="antismash"
     gene            complement(3271..5010)
                     /locus_tag="LC193_RS13155"
                     /old_locus_tag="LC193_13155"
     CDS             complement(3271..5010)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138617.1"
                     /locus_tag="LC193_RS13155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13155"
                     /product="cholesterol oxidase substrate-binding
                     domain-containing protein"
                     /protein_id="WP_226074242.1"
                     /transl_table=11
                     /translation="MANTPELPSRRGVLRTAAAAGAFGLAAHTAIGRAVAATPAPDLPG
                     GLIPYRLPYLNWAGEIAHPGLWTCAPRDGQQVADLANWAHAAGWRLRARGKAHTWSPLT
                     ITPGTDADAPVLLVDTTKHLTAMALVPPPAGAPGAVRAQTGVTLEELLGYLAGHGLGVT
                     NTPAPGELTLGGTLAIDAHGTSVPAAGEAPRPGHTYGSLSNLVLELTAVVWDEANGRYA
                     LRTFTRGTDPECDALATHLGRAFVVEAVLQAGEETPLRCVSRVDVPADELFAAPGSPEA
                     AGGRTFADYLDAAGRVETIWFAFTDKPWLKVWSLSPERPATARPVLGPYNYPFSDLVPT
                     PVSRLVGRLTAEAAWYLAPQLGALQYTVAATGLTTSLATDLWGASHHLTFYLRPTTLRE
                     TANGYAILTRRADVQRVISEFAGFYRERLEAWADAGRYPVNGQVEIRVGGLDQPADVAV
                     AGARPPLLSVVRPHPDHPEFDCAVWVDVLTLPGTPGAAEFYRELERFCLDTYDGGHALV
                     RVEWSKGWGYTDAEAWADQEVIGEVVPASYGAGEWAEGTGLLRGLDPHGVFGNAFLDEL
                     LAP"
     misc_feature    complement(4990..4992)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(5032..5046)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.24"
                     /tool="antismash"
     gene            5131..6333
                     /locus_tag="LC193_RS13160"
                     /old_locus_tag="LC193_13160"
     CDS             5131..6333
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522002.1"
                     /locus_tag="LC193_RS13160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13160"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_226074243.1"
                     /transl_table=11
                     /translation="MSLGADLRRLRRLAGLTQETLADRAGVSVDVVKKLEQGRKTSARL
                     PTLHALAAGLGVELTALLGEPPAVASGSLVDSPRLVALRRSIAPPLLALPPEPSTPHPS
                     PTAVKHRIASGWTQYHKANFPALMSALPGIIDDSRFAASVGTEQQRARGAALLAKSLQL
                     GGHVAIRLGKTDLALSALERAMHAAEQSADVLLPGMISTSVAWSYQRQARLEDALHLAI
                     HAADRVEQGRTDTAEGVRVRGGLLMSAATSYARSGDYERADEMMTSAENAAKRLAHLPP
                     PEDGRLVSVFSRSSVRIERVRLAVQHKRPQEALDLARGMRLSKDVPPSWRAWLLLDIAR
                     AHTDLGNAEKAVATLERLHRVAPAWLGHHTLAVAIVRDLWSLPQRPTGLRRLAGRLGVA
                     D"
     gene            complement(6981..7172)
                     /locus_tag="LC193_RS13165"
                     /old_locus_tag="LC193_13165"
     CDS             complement(6981..7172)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.5"
                     /locus_tag="LC193_RS13165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13165"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_226078577.1"
                     /transl_table=11
                     /translation="MGRAQWFTSSHSSGNGECVEVADAEDGVLTRDSKQRSGPVLVSRS
                     EGWQAFVAGVVRGDFGKG"
     gene            complement(7374..7643)
                     /locus_tag="LC193_RS13170"
                     /old_locus_tag="LC193_13170"
     CDS             complement(7374..7643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957774.1"
                     /locus_tag="LC193_RS13170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13170"
                     /product="hypothetical protein"
                     /protein_id="WP_226074244.1"
                     /transl_table=11
                     /translation="MTTKWEADPAASFARRLGKSSHALGQTSGNASCPDVWELDNGDIA
                     VIGTDLTPDYAGRLPTGVSVDPGERLVIIPRATLVAAKTDIPDA"
     gene            complement(7724..9277)
                     /locus_tag="LC193_RS13175"
                     /old_locus_tag="LC193_13175"
     CDS             complement(7724..9277)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018487775.1"
                     /locus_tag="LC193_RS13175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13175"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_226074245.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 6.4e-07, bitscore:
                     27.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 5.7e-10, bitscore: 37.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGRRPGRDRRARVLPPAGNRDRVTGTPPSAAVVGGGIAGLAAAT
                     ALAERGVRVTLVERGDALGGRLAGHRVTLADGSAATMTRGFHAFFRQYYNLRQLLRRAD
                     PDLRMLTGLPDYPLLHREGARDSFARVPRTPPFNALGFVALSPSFGARDLLRMRPAAAL
                     PLLDVRVPEVYRRLDGTSAHAFLSAIRFPTAARHLAFEVFSRSFFADPAELSAAEMALM
                     FHIYFLGSAEGLLFDVPAEPFPQALWEPLTDHIARLGARVRPGTAAERLAPADGDALHL
                     TTADGARERFDAVVLALDTDGLRDLVARSPALGDAEWRARIDKLRAAPPFLVSRYWLDR
                     PVARHRPGFLGTSGYGALDNITVLNAFEGEAARWAHRTGGCVLELHAYARPPGADRAAE
                     QRLLLARAREVYPELREARVIDERHAWHADCPLFPVGGWTDRPPVRTPHPAVMLAGDLV
                     RTTLPVALMERAATTGFLAANALLARWGVRGQTLWTVPDRGRSAAFRTLATLARPTHRP
                     "
     gene            complement(9274..10011)
                     /locus_tag="LC193_RS13180"
                     /old_locus_tag="LC193_13180"
     CDS             complement(9274..10011)
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677064.1"
                     /locus_tag="LC193_RS13180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13180"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_226074246.1"
                     /transl_table=11
                     /translation="MAIDDNRAPAALLRDGDLAAAFDRAAAGYDRLVACNPGYHAHLRR
                     SARRLGPRPGGAAPPRLLDLGCGTGASTAALLAAHPGARVTAVDASAGMLARATAKRWP
                     PGVTFVHAPAERLADAGVTGPFDGVLAAYLFRNVADPDRLLRDVRQLLAPGGRLAVHEY
                     TLSGRPSHRAVWAAVCGGLVRPVGALTGDRQLYRHLWHSVIAFDTAAQFTGRVRRAGFH
                     AVRAAPMPGWQRGIVHTVVGTAA"
     gene            complement(10001..11242)
                     /locus_tag="LC193_RS13185"
                     /old_locus_tag="LC193_13185"
     CDS             complement(10001..11242)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Lycopene_cycl"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849732.1"
                     /locus_tag="LC193_RS13185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13185"
                     /product="lycopene cyclase family protein"
                     /protein_id="WP_226074247.1"
                     /sec_met_domain="Lycopene_cycl (E-value: 5.1e-85, bitscore:
                     284.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDAVVIGAGAAGLTLAHRLVETAGAEVLLVTAPPGPLRPAERTW
                     CWWEAPGGPYDDALVTSFHRLRVHGRAGDVADRAPRRLRYKMLRSGALETLVRDRLAGR
                     AAFREVIATVTDMRDAPGGGAEVRGTDPEGRPVLLRARWAFDSRPPRRLPPARTTLFQH
                     FRGWFVRTPHAAFEPGVADLMDFRVPQPPRGVAFCYMLPLGTHEALVEYTEFSPEPLPR
                     EAYERALRHYTRHHLALPDPTIAATEAGVIPMTDGVFPRRVGTALFRVGIAGGAARPAT
                     GYAFAAAQRQSRAVAAALRAGLPPVPPHPHSTRSRAMDAVLLAALDTGRVCGADLLARL
                     FHEVPTERLLRFLDGDTRWWEDIAVGLRTPARPMLRTALTLPLRPRRPTPAPATLDEHP
                     DHGHPRKASVNDGD"
     gene            11324..12109
                     /locus_tag="LC193_RS13190"
                     /old_locus_tag="LC193_13190"
     CDS             11324..12109
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003985859.1"
                     /locus_tag="LC193_RS13190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13190"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_226074248.1"
                     /transl_table=11
                     /translation="MTEGEETRRGVAGSVQSVERAVSVLEALARSGGAGVTEIADEIGV
                     HKSTASRLIGVLESRGLVDQEKERGKYYLGAGILRLAGAAAIRLDISQESAPVCRRLAE
                     ATGETANVAVLDGDAAVNIMQARGPAEVAAYNWLGRRTPLHATASGKVLLAAMPTAVRE
                     SLLAREQQRFTARTVTAPAALRAAADEVAAEGFAVTREELEAGLNAVAAPVRRYDGTVI
                     GAIGVSGPVYRMGEERLSELAESCTSAAGELSRRLGFGS"
     gene            12242..14662
                     /locus_tag="LC193_RS13195"
                     /old_locus_tag="LC193_13195"
     CDS             12242..14662
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058717.1"
                     /locus_tag="LC193_RS13195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13195"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_226074249.1"
                     /sec_met_domain="DAO (E-value: 2.3e-49, bitscore: 167.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAARADTRVVIIGAGIVGCALADELTARGLREVTVLDRGPLFAGP
                     GSSYHAPGLVFATSPAKVLSDFARYTIDKYRSLGCFSPVGGLEVATTPERLADLARRAG
                     LAASWGIEAERVSARRCAELWPLLGADRVLGGLHTPRDGLADAALACRLQAERAMARGA
                     TFHGGHTVTGIERGPDGAVVAVRTDRGDFPADAVVSAAGFWGPVVGAMAGVPVPLLPLA
                     HQYARTGPVPGLDPDARLPILRHQDRDLYVRQHGDALGIGSYGHRPMPVDPFTLTASEL
                     PFSAEEFAPAWRDAAELLPALGGPGPASGFDGVFSFTPDGMPLLGQVREVPGLWLAEAV
                     WVTHSAGAARAVAQWLAEGRPATDTHLCDVHRFTGAQLSPAYVADRGAQSFVEVYDIIH
                     PLDPPARPRPLRVGPFHVKHRELGAHQLEYAGWERPQWFEANAPLAEALPPGAVPPRDA
                     WAARHWSPIAAAEALATRERVALFDMTPLTRLEVTGPGALAFLRRMTTGRVDRGPGSVG
                     YALLLDHAGGVRSDITVARLARDHWQIGCNGPLDLDWLLRHAPTDGSVAVRDITPGTCC
                     LGVWGPLARELVAPLADADVSHEAFGYFTARRLHIGHVPVTAMRLSYVGELGWELYTTA
                     DLGPLLWDTLWRAGQRLGVLAAGRAAFTSLRLEKGYRAWGVDMTTEHDPYEAGIGFALR
                     PGDRDFIGGAALAGRSEATARRRLACLTLDDPAAIVLGGEPVYAADEPARPAGYVTSAG
                     YGHTVGRAIAYAWLPAALAVPGTGTHVAYFGERLAATVRAEPLLDPELSRIRR"
     misc_feature    13136..13138
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14739..15896
                     /gene="solA"
                     /locus_tag="LC193_RS13200"
                     /old_locus_tag="LC193_13200"
     CDS             14739..15896
                     /EC_number="1.5.3.2"
                     /GO_function="GO:0050131 - N-methyl-L-amino-acid oxidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="solA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324993.1"
                     /locus_tag="LC193_RS13200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13200"
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="WP_226074251.1"
                     /sec_met_domain="DAO (E-value: 1.1e-45, bitscore: 155.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASGYDVIVLGLGGMGSAAADHLAARGARVLGLEQFGPVHDRGSS
                     HGGSRITRQSYFEGPAYVPLLLRAYELYERLARDADREIALLCGGLMIGRPDSRTVAGS
                     VRSATAWDLPHEMLDAREIRARFPTLAPADDEVALFERRAGLLRPEATVAAQLELAAAA
                     GAELRFEEPVTAWEALPGGRGVRVTTPDGVYTAGHLVVCPGAWAPRQLADLGVPFTVER
                     QIMYWFEPEGGTAPFEPDRHPVYVWEAPEGTQIYGFPALDGPGGGAKVAFFRQGIPCTP
                     ETIDRTVHPEEVAEMAAFAGARLPALPGRLLRAVTCMYTTTPDEHFVIAPHPAHAAVTV
                     ACGFSGHGFKFVPVVGEILADLALTGSTPHPIELFSPGRLGGRQT"
     gene            15893..17014
                     /locus_tag="LC193_RS13205"
                     /old_locus_tag="LC193_13205"
     CDS             15893..17014
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541030.1"
                     /locus_tag="LC193_RS13205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13205"
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_226074253.1"
                     /transl_table=11
                     /translation="MTTTPITATGLLPTLPGPAYTDPETFRREQERIFEARWFCAVRAG
                     DLLTPGSFRTVTVGRENVLVTRGRDGALRAFLNVCRHRGARLCTEESGQVRRTFRCPYH
                     AWTYAPDGRLVAAPNLKDLPGLDRSAHGLIGVALREWLGYAWVCLADEPPSFDETVIGS
                     VSARLGDDRAVERYRPADLVLGRRVTYDVRANWKLIVENFMECYHCATIHPELVQVLPE
                     FAGGWAAQAAVGHGAAFAPDVEGFTVDGSGGFGRLPGLADEQDRRYFATTIRPQVFVNL
                     VPDHVIVHRMFPLAPDRTRVECDWLYAADVIDGGADVSASVELFHRVNEQDFAACERTQ
                     PAMHSRAYAAGGVLVPTEHHITEFHHWVTSLLA"
     gene            17092..17793
                     /locus_tag="LC193_RS13210"
                     /old_locus_tag="LC193_13210"
     CDS             17092..17793
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020893.5"
                     /locus_tag="LC193_RS13210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13210"
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="WP_226074255.1"
                     /transl_table=11
                     /translation="MEAPVAVNAEERAEERAERRARAAPRAGRRAAWPRLALLALLLAL
                     AAGAAFAAGGDAVPGTGSWPLFVAGYALGTLAFVPKPALTAAAGAAFGAVSGIAVAAAG
                     TALGALLAFGAARLLGRDAVGPLLTRHRATAALEERLARRPFTGVLVLRLVPVMPFAAV
                     NLGAGVCRVGWLPFTAATLIGTLPGNAAYALAGAAATAPASPALWSAAAVALALTACAA
                     LWRRRRLRAAG"
     gene            complement(18114..20030)
                     /locus_tag="LC193_RS13215"
                     /old_locus_tag="LC193_13215"
     CDS             complement(18114..20030)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018486855.1"
                     /locus_tag="LC193_RS13215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_13215"
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_226074257.1"
                     /transl_table=11
                     /translation="MLQSALLGPMEIRVNGQLRTPSAPMARRVLAVLLTHVDRVAPTEL
                     LIDELWGEHPPMRARKTVQTYIYQLRKLLSDDGGSARDPGPVERHAHGYRLSLGGGRLD
                     LSEFQESLRQGREALGRGQASDGAEALRRGLELWRGAALEDVEMGPVLAAQAAKLENLR
                     LRALEQRIAADLARGLHHSLLEEIRDLTYAHPLHEEFCAQLMMAAERCGQRGEALAAYA
                     RLHRAMVEQLGLEPSERLQRLQRGALTGEERRAEAPAGPRARPARPAAAPFQLPPALRD
                     FVGRRGEIDRVERAVRGVGSSSGVRIVTVTGGPGVGKTEVALQVAHRLQGDFPDGQLGV
                     RLHGEDGAARHPAETLEGLLTAAGFDRRSLPHRADDLAAMFRGWAAARRFLLLLDDAAG
                     SDQVLPLLPAGADNVVIVTSRCRFAELPGAVTPVELGPMPQPEALRLLTRVVGAERAGR
                     EPEAAAAVAARCEGMPAAIRAVGSRIAAWPSRGLADFAARLDDERQRLEELSSPHLNVR
                     RYLIQSAARLPRGAREVLTELSRTEETDVTVAYLARRLHRSAGSIERSVELLADCHMLT
                     PLPRDGRHVLRVAPLFRLALALGAPEQRSEPAPAGRDMMLRYSARARPVRRLAPLRSAL
                     RGA"
     misc_feature    complement(19821..19823)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    19987..20000
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 17.7"
                     /tool="antismash"
ORIGIN
        1 cgtaggacgc ccggtcgtca cggcgctcgt acgacggccg gtcgtcgcgc cggaacccgc
       61 cgccgctgcc gcgccggttg tcgtccccgc cgcgcgggcg gaagccctcg ccgccgcccc
      121 ggggcctgaa accctcgccg cggtcgtcgc ggcgcgggaa cggccgccgc tcgtcacggc
      181 ggaacccgcc gccgccaccg cgccggttgt cgtccccgcc gcgcctgaag ccctcgcctc
      241 ggtcgtcgcg gcgcgggaac ggccgccggt cgtcgcgccg gaacccgccg ccacccggcc
      301 tgcggttgcc gtgctcctcc tggcgcccgg tctcggcccg cgcggccttc tcggcacggc
      361 gcgcctcgcg cgccgcctcc cgctcggctt cgcgctcggc ctcggcgagc gcctgcttgc
      421 gctgctccgc ggcctgggcg atggcctcgg ccgggtcgtc cccgcgttcc cgcgcggcgc
      481 ggccggtgag gcgttcggcc tcgtcccgca gctccgtggc gcggccctgc gccttctcca
      541 gctcgcgggc gaggcgggcc acctcaagct cggcgtgccg gacggcgccc atggccgaat
      601 ccgcctgcac ctcggtgagg gaacgcgcgc cgatgatgcc ggccacgtcc tcgtcgaaca
      661 gctccccgcg cccgatgacg tgccgcgcgg cgtgcacgcc cgcgtcctcc atcagccgga
      721 agatcgtccg ccgctggtgc ggcagcgcga gcgacacgac cgtgccggaa cgccccgcgc
      781 gcgcggtgcg gccggaacgg tgcaggtagt ccttgtggtc ggccgccggg tcgacgttca
      841 gcacgacatc gatgtcgtcg acgtggatgc cgcgcgcggc gacgtccgtg gcgaccagga
      901 cggccacgcg gccgtccttg aagtcggcca gggtgcgggt gcgggcgccc tgcgtcatgc
      961 cgccgtgcag cgcgtccgcg cgcacgccgg cctcgcgcag ctggcccgcg acgcggtcgg
     1021 cgccgagctg ggtgcgcacg aacacgatcg tgcgcccctc gcgcgccgcg atggccgcgg
     1081 tcagcggggc cttgtcgcgc ggcttcacga ccagcacgtg gtgcgacatg gtggtgaccg
     1141 cgccctgcgc cgcgtccacc tcgtggctga cggggtcgac gaggtagcgc ttcaccagcg
     1201 tgtcgatctc gtgctcaagc gtggccgaga acagcatgcg ctggccgccc gcgggcacct
     1261 ggtcgagcag ttcggtgacc tcgggcagga agccgaggtc ggccatctgg tcggcctcgt
     1321 cgagcacggc gacctcgacg tcgtcgagcg agcacgcgcc gcggccgatc acgtcgcgga
     1381 gtcggcccgg cgtggcgacg aggacgtcca cgccgcgttc gagggcgtag atctggttgc
     1441 ccatggaggt gccgccgcac acgaccttca ggcgcagccc gagcacgtcg ccgtacggct
     1501 caagggcgtc ggagacctgc atggccagtt cgcgggtggg cgtgaggatc acggcgcgcg
     1561 ggcgcttggg cgccgtgcgc ctgccggcca ggcgggccag cgtgggcagg ccgaagctca
     1621 gcgtcttgcc ggagccggtg cgcccccggc cgaggatgtc gtggccggcc agcgcgtcgg
     1681 gaatggtggc cgcctggatg gggaacgggg tggtcacccc gttctcggcg agcttgcgca
     1741 caacgttctg cggcaggccc aggtcggcga aggtggtggt gggctcgtcc aggggaagaa
     1801 gtgcctctgg cgtcgagacg gacatgcgaa gtgagtacct tccggagtct gaggtggtcg
     1861 gcacgcgcct tagctccgta ggtgctgttg accgcctgga tgcgatcagc cacggctaga
     1921 cgaggaacgc gccacacggc gcgctgctgc tgggcgccgg gcaagtttga tgggatcaaa
     1981 cgatctacaa gcatacgcac cgtgtggggt cccgtgcaaa cggctcatga gccatcctcg
     2041 gggggcggtt ccgagggcgc gggttccgcg gtcggggagg gcggcggcgg ctccggctgc
     2101 ggctcgggcg cggggggcgg ttccggctgg ggttccggct cgggcgccgg gttcggttcc
     2161 ggctcaggcg cgggctccgg cgggcgcgcg gcgggtggcg gggcgggcgg ctgggcgcgc
     2221 ggggagctgc ggggcgcctc gcccgtgggc gcgccgggct cggggtccgc gcccggtgtg
     2281 ccggcggcgg gccgttccgc gctgggaacg gcgtgccccg acggcggctc gtccgcgtcg
     2341 ccgccctcgg gcgggacggt ccgcggggcg tccgtggcgg caggcgccac gggcttgccc
     2401 ggccgttcct cgggctcgac ggtcaggcag ccgccgaggg cggccaccgc gacgagggcg
     2461 gcgaccggcg cgaggcggtg ggggcggcgc acgggcggac acctccgggg gcgggggcaa
     2521 gcacttacgc gtgactcaac tctcaccccc ggacggagga cacggacccg agccaaccga
     2581 aacggaccag tcatcgacga ccaggaacgg acagccgcaa acggttgtgc acaccctcgt
     2641 cgaccggctc gatcgtcgac cggctcgcgg ctcacccgta accgagcgcg tgcagccgtt
     2701 cgtcgtcaat cccgaagtgg tgcgcgatct cgtgcaccac ggtgatctcc acctcctgca
     2761 ccaccagctc gcggtcgccg ccctcacggc ggcacagccg cagcgtcggc cccatgtaga
     2821 tggagatccg gtccggcagc accccggcgt accactcgcc ccgctcggtg agcggcgtcc
     2881 cctcgtacag gccgagcagc tcagggtcct cagggggcgg ctcgtcctcc acgaacacgg
     2941 cgacgttgtc catcagccgg gtcagctccg gcgggacccg gtccagcgcc tcactgacca
     3001 gttcctcgaa ctcctcgcgc gtcatctcca gcaccccgcc attgtccttc ggcggaaaag
     3061 ttttggtgat cccccgcgcg atcgcctatg ctgctcgcgc gtcccatact ggcccccatc
     3121 gtctagcggc ctaggacgcc gccctttcaa ggcggtagcg cgggttcgaa tcccgttggg
     3181 ggtacacgcc gaggtgaggt gccggccgac cggcctcact ccccggtcga ccggttcccg
     3241 gccccgccga ggcaggaccg ggacagcggg tcagggcgcg agcagttcat cgaggaacgc
     3301 gttgccgaac accccgtgcg gatcgagacc gcgcagcagc ccggtgccct ccgcccactc
     3361 ccccgccccg taggacgcgg gcacgacctc gccgatgacc tcctggtcgg cccacgcctc
     3421 ggcgtccgtg tagccccagc ccttggacca ctcgacgcgg accagcgcgt gcccgccgtc
     3481 gtaggtgtcc aggcagaacc gttccagctc acggtagaac tcggccgccc ccggcgtgcc
     3541 cggcagcgtg agcacgtcca cccacaccgc gcagtcgaac tccgggtggt ccggatgcgg
     3601 gcgcaccacg gacagcagcg gcggtcgcgc cccggcgacg gcgacatctg ccggctggtc
     3661 gaggcccccg acgcggatct ccacctgccc gttcacgggg tacctgcccg cgtcggccca
     3721 cgcttcgagc cgttcccggt agaacccggc gaactccgag atcacccgct gcacgtccgc
     3781 cctgcgggtc aggatggcgt agccgttggc cgtctcccgc agcgtggtcg gccgcaggta
     3841 gaacgtgagg tggtgcgagg cgccccacag atccgtcgcg agcgacgtcg tcagcccggt
     3901 cgccgccacc gtgtactgca acgcgcccag ttgcggtgcc agataccagg cggcctcggc
     3961 ggtcagccgc cccacgagcc gtgaaacggg cgtggggacc aggtcgctga acgggtagtt
     4021 gtacggcccc agcaccggtc gcgccgtcgc gggacgctca gggctgaggc tccagacctt
     4081 cagccacggc ttgtccgtga acgcgaacca gatcgtctcc acgcgcccgg ccgcgtcgag
     4141 gtagtcggcg aacgtccgcc cgcccgccgc ctcggggctg cccggcgcgg cgaacagctc
     4201 gtccgccggc acgtccacgc ggctgacgca gcgcaacggc gtctcctcgc ccgcctggag
     4261 caccgcctcc acgacgaacg cccgcccgag gtgcgtggcc agcgcgtcgc actcggggtc
     4321 cgtgccgcgc gtgaacgtcc gcagcgcgta ccggccgttc gcctcgtccc agaccacggc
     4381 ggtcagttcg agcacgaggt tgctgaggct gccgtaggtg tggccggggc gaggggcctc
     4441 cccggcggcg ggaacgctcg ttccgtgcgc gtcgatggcg agcgtgccgc ccagcgtcag
     4501 ttcgccgggg gcgggggtgt tggtcacgcc gaggccgtgt cccgcgaggt agccgagcag
     4561 ttcctcaagc gtcacgccgg tctgcgcccg gaccgcgccc ggcgccccgg cgggcggcgg
     4621 caccagggcc atcgccgtca ggtgcttcgt ggtgtcgacc agcagcaccg gcgcgtccgc
     4681 gtcggtgccc ggcgtgatcg tcagcggcga ccaggtgtgc gccttgccgc gcgcccgcag
     4741 ccgccagccg gcggcgtggg cccagttggc gaggtcggcg acctgctgcc cgtcgcgcgg
     4801 cgcgcaggtc cacaggcccg ggtgggcgat ctcgcccgcc cagttcaggt agggaaggcg
     4861 gtaggggatg aggccaccgg gcaggtcggg cgccggggtc gcggcgacgg cgcgcccgat
     4921 cgcggtgtgg gccgcgagcc cgaaggcccc ggccgcggcg gccgtgcgca ggacaccgcg
     4981 ccgggaaggt aactcaggtg tgttcgccat acggcggacg gtagtgagcc cagcgcacgt
     5041 tgagaaagac cgcgcgcacg gcccagccgc gcgcctgcgg actgtcgcca ccgcgcctgc
     5101 ccgggctcgt gcccgcctac tctggggagc atgagccttg gtgctgatct ccgtcggctg
     5161 cgccgcctcg cgggactcac acaggagacc ttggccgacc gggccggcgt gtccgttgat
     5221 gtcgtcaaga agctcgaaca aggccggaag acgtcagccc ggctgccaac cctgcacgct
     5281 cttgccgccg gtctgggcgt cgagctgacg gcgttgctgg gcgagccgcc cgcggtggcc
     5341 agcgggtcgc tcgtcgactc cccccggctt gtggcgctgc gccggtccat cgctccaccg
     5401 ctgctcgcgc tcccgccgga acccagcacg ccgcacccct cgccgacagc cgtcaagcac
     5461 cgcatcgcgt cgggctggac gcagtaccac aaggcgaact tccccgccct gatgtcggct
     5521 ctccccggaa tcatcgacga cagccgcttc gccgcttccg tcggcaccga gcagcagcgg
     5581 gcgcgcggag cggcgctcct ggcgaagtcg ctgcaactgg gcgggcatgt ggcgattcgg
     5641 ctgggcaaga cggacctggc gctctccgcc cttgagcgcg cgatgcacgc ggcggagcag
     5701 tcggcggatg tgctgctgcc cggaatgatc tccacctccg tggcgtggtc ctaccagcgc
     5761 caggcccggc tggaggacgc gcttcacctg gccatccacg ctgccgaccg cgtcgagcag
     5821 ggccgcacgg acacagccga aggcgttcgg gtccggggcg gcctgctgat gtccgccgcc
     5881 acgtcgtacg cacggagcgg cgactacgaa cgcgccgacg agatgatgac gtccgccgag
     5941 aacgccgcga aacgactcgc gcacctgccc ccgccggaag acggacggct ggtgagcgtt
     6001 ttcagccgct cctccgtacg catcgagcgc gtccgactcg ccgtccagca caaacgtccg
     6061 caggaggcac tggacctggc acgcggcatg cgtctgagca aggacgtccc accgtcctgg
     6121 cgcgcgtggc tcctgctcga catcgcgcgg gcgcatacgg acctgggcaa cgcggagaag
     6181 gccgtggcga ctctggaacg actccaccgc gtcgcacccg cgtggctcgg ccaccacaca
     6241 ctcgcggtcg ccatagtccg agacctctgg tcacttcccc agcggcccac cggacttcgc
     6301 cgcctggcgg gacggctggg agtggctgac tagcgcgcga aacggggacg ttccatccct
     6361 gcagacgccg caccaatccc gccacgctga gtgcccgaag gcctctgtcg gcgccaggaa
     6421 taccgttcgg cgcaccctcc gtggcgcacc cgaacctgaa ggggccgcta ccgagccggg
     6481 cgcacggtcg cggagtccgc gcccaggtgc cgcgatcctc agccgccccg aaggacagcc
     6541 gccacccagc ggcggtgtcg acgtcaagca gatgtccggc aagttgcaat tttcagccgc
     6601 cccaaagaac ggccgccacg acctcccggc cccgccggag cgggtccggc tgcgggttgc
     6661 gaccctcagc cgccccgaag gacggccgcc acctcctgcg ttgcccggcg cacggccaga
     6721 ttgcggggtt gcgatcctca gccgttccgg gggacggccg ccacccagcc gtaccggtcc
     6781 agctgctcca cgaacaggcg gttgcgatcc tcggccgttc cgggggacgg ccgccacggt
     6841 gtttgaccag tggtttcggc atgcggctgg ggcaccaacc cgagtcaaca cggggcaaag
     6901 acgagcaatg cgggcattct ccttcggtgc ggcccgcgcg tcgtgtgcgc acttggggtt
     6961 ccgaacctcc gtgtcagtcc tcaccccttg ccgaagtcac ctcgcacgac gcccgcgacg
     7021 aatgcctgcc agccttcaga gcgactgaca agcacaggcc ccgaacgctg tttgctgtcc
     7081 cgggtgagga ctccgtcctc cgcgtccgcg acctcaacac actcaccgtt gccgctgctg
     7141 tgactcgacg tgaaccactg tgccctgccc aggtgatcag ttctgtttca tagcctcctg
     7201 ccacttccgc gatcaacaac tgctgcttcc cggacaccgg cggacgccgc ttcggaccgt
     7261 cgactccgcg cggcagtgcg gcggtgcggc ggtgcagtgc ggcgggcgtc cgtgaagcgg
     7321 ctgggggcct gaaggacttc ggccgtgcct cgcccatggc gtcggccagc aggtcaggca
     7381 tccgggatgt ctgtcttggc cgcgacgagc gtcgcccggg ggatgatcac cagccgctcg
     7441 ccggggtcga cgctcacccc cgtggggagc cgtcccgcgt agtcgggggt caggtcggtg
     7501 ccgatgacgg cgatgtcccc gttgtccagc tcccacacgt cggggcagct ggcgttgccc
     7561 gaggtctggc ccagcgcgtg cgacgacttg cccagtcgcc gtgcgaacga cgccgccgga
     7621 tcggcctccc acttcgtggt catgtcccct ccccttgagg ccagttcgtc ccagcgctcc
     7681 gtggcgagac tatcactcaa cgcgttcatc cggccatagt gcgtcacggc cggtgcgtgg
     7741 ggcgggccag ggtcgccagg gtgcggaacg cggccgagcg gccccggtcg ggaaccgtcc
     7801 acagggtctg gccgcgcacg ccccagcggg cgagcagggc gttggcggcc aggaagccgg
     7861 tggtggcggc ccgttccatc agcgcgaccg gcagcgtcgt gcgcaccagg tcgcccgcga
     7921 gcatcaccgc cgggtgcggg gtgcgcacgg ggggccggtc ggtccagccg ccgacgggga
     7981 acagcgggca gtcggcgtgc cacgcgtgcc gctcgtcgat cacgcgcgcc tcgcgcagtt
     8041 cggggtagac ctcgcgcgcg cgtgccagca gcagccgctg ctcggccgcc cggtcggcgc
     8101 ccggcggccg ggcgtaggcg tggagttcga gcacgcagcc gccggtgcgg tgggcccacc
     8161 tggcggcctc gccctcgaac gcgttcagca ccgtgatgtt gtccagtgcc ccgtagccgc
     8221 tggtgccgag gaagccgggc cggtgccgcg ccacgggccg gtccagccag tagcgcgaca
     8281 cgaggaacgg gggcgcggcg cgtagtttgt cgatgcgcgc gcgccactcg gcgtcgccga
     8341 gcgcgggtga acgcgccacc aggtcgcgca gcccgtccgt gtcgagcgcg agcacgacgg
     8401 cgtcgaagcg ttcgcgcgcc ccgtcggcgg tcgtcaggtg gagcgcgtcg ccgtcggcgg
     8461 gtgcgagccg ttccgcggcg gtgccggggc gcacccgcgc gcccaggcgc gcgatgtggt
     8521 cggtcagtgg ttcccacagg gcctggggga acggctcggc gggcacgtcg aacagcaggc
     8581 cctcggccga gccgaggaag tagatgtgga acatcaacgc catctcggcg gcggacagtt
     8641 cggccgggtc ggcgaagaag ctgcgcgaga acacctcgaa cgccaggtgc ctggccgccg
     8701 tggggaagcg gatggcggag aggaacgcgt gggcgctggt cccgtcgagg cgccggtaga
     8761 cctcgggcac ccggacgtcc agcagcggca gcgcggcggc gggccgcatg cgcagcaggt
     8821 cgcgggcgcc gaacgagggg ctgagcgcga cgaacccgag ggcgttgaac ggcggggtgc
     8881 gcggcacgcg cgcgaagctg tcgcgcgccc cctcccggtg cagcagcggg tagtcgggca
     8941 gcccggtcag catccgcagg tccgggtcgg cgcgccgcag cagttgccgc aggttgtagt
     9001 actgacggaa gaacgcgtgg aagccgcgcg tcatcgtggc ggccgagccg tccgcgagcg
     9061 tcacgcggtg gcccgcgagc cgcccgccga gcgcgtcgcc gcgttcgacg agggtgacgc
     9121 gtacgccgcg ttccgcgagc gccgtggccg cggcgagtcc cgcgatgccg ccgcccacga
     9181 cggcggcgct gggcggggtg ccggtgacgc ggtcgcggtt ccccgccggg ggcagcaccc
     9241 gggcgcgccg gtcgcggccc ggccgccggc cggtcacgcc gcggtcccga cgacggtgtg
     9301 cacgatgccg cgctgccagc cgggcatggg cgcggcgcgc acggcgtgga acccggcgcg
     9361 gcgcacgcgg ccggtgaact gcgcggcggt gtcgaacgcg atgacgctgt gccacaggtg
     9421 ccggtacagc tgccggtcgc cggtcagcgc gcccaccggg cgcaccaggc cgccgcacac
     9481 ggcggcccac accgcgcggt gcgacggccg gccgctgagc gtgtactcgt ggacggcgag
     9541 ccgcccgccg ggggcgagga gttgacgcac gtcgcgcagg aggcggtcgg ggtcggcgac
     9601 gttgcggaag aggtaggcgg ccaggacgcc gtcgaacggc ccggtgacac ccgcgtccgc
     9661 gaggcgttcc gcgggggcgt ggacgaacgt gacgccgggt ggccagcgtt tggccgtggc
     9721 gcgggcgagc atgcctgccg aggcgtcgac ggccgtgacg cgcgcgcccg ggtgggcggc
     9781 gagcagcgcg gccgtcgagg cgccggtgcc gcagccgagg tcgagcagcc ggggcggggc
     9841 ggcgccgccg gggcgcgggc cgaggcggcg ggccgagcgc cgcaggtgcg cgtggtagcc
     9901 ggggttgcag gccacgagcc ggtcgtagcc cgcggcggcc cggtcgaacg ccgccgccag
     9961 gtcgccgtcg cgcagcagcg cggcgggcgc ccggttgtcg tcaatcgcca tcgttcacgc
    10021 tcgccttccg tgggtgtccg tggtcggggt gctcgtcgag ggtggcgggc gcgggggtgg
    10081 gccgccgggg gcgcagcggc agggtgagcg ccgtgcgcag catcgggcgc gccggggtgc
    10141 gcagcccgac cgcgatgtcc tcccaccagc gggtgtcgcc gtcgaggaac cgcagcagcc
    10201 gttcggtcgg cacctcgtgg aacagccgcg ccagcaggtc ggcgccgcac acccggccgg
    10261 tgtcgagcgc ggcgagcagc accgcgtcca tggcgcgcga gcgcgtcgag tggggatgcg
    10321 gcggcacggg cggcaggccg gcgcgcagcg cggcggcgac ggcgcggctc tggcgctgcg
    10381 cggcggcgaa cgcgtagccg gtggccgggc gggcggcgcc gcctgcgatg ccgacgcgga
    10441 acagggccgt tccgacgcgg cgcgggaaga cgccgtcggt catggggatg acgcccgcct
    10501 cggtcgcggc gatcgtgggg tccgggagcg cgaggtggtg gcgcgtgtag tgccgcagcg
    10561 cgcgttcgta cgcctcgcgg ggcagcggct cgggcgagaa ctcggtgtac tcgaccagcg
    10621 cttcgtgcgt cccgagcggc agcatgtagc agaacgcgac gccgcgcggc ggctgcggca
    10681 cgcggaagtc catcaggtcg gccacgccgg gctcgaacgc ggcgtgcggg gtgcgcacga
    10741 accagccgcg gaagtgctgg aacagcgtgg tgcgggcggg cggcagccgg cgcggcggcc
    10801 gggagtcgaa cgcccagcgc gcgcgcagca gcaccggccg cccctccggg tccgtgccgc
    10861 gcacctcggc gccgccgccc ggggcgtcgc gcatgtccgt gacggtcgcg atgacctcgc
    10921 ggaacgcggc ccggcccgcg agccggtcgc ggaccagcgt ttcgagggcg ccggagcgca
    10981 gcatcttgta gcgcaggcgg cgcggcgcgc ggtcggcgac gtcgccggcg cggccgtgca
    11041 cgcggaggcg gtggaaggac gtgacgaggg cgtcgtcgta ggggccgccg ggcgcctccc
    11101 accagcacca ggtgcgttct gccgggcgca gcggccccgg cggcgcggtc acgagcagaa
    11161 cctcggcccc ggccgtttcg acgagccggt gcgcgagggt gagtccggcc gctccggccc
    11221 cgatgacgac ggcatccacc acgtcccgat gctcacccag gccgccgcgt caccggccgc
    11281 ccgacacggg gccgcccggg tgacgcgcgc ctacgatgag gtcatgaccg agggtgagga
    11341 aacgcgtcgg ggcgtggccg gatcggtgca gtcggtggag cgggcggtga gcgttctcga
    11401 agcgctggcg aggagcggcg gggccggggt cacggagata gcggacgaga tcggggtgca
    11461 caagtccacg gcgtcgcggc tgatcggggt gctggagagc cggggcctgg tggaccagga
    11521 gaaggagcgc ggcaagtact acctgggggc gggcatcctg cggctggccg gggccgcggc
    11581 catcaggctc gacatctcgc aggagagcgc accggtgtgc cggcggctcg cggaggcgac
    11641 gggcgagacg gcgaacgtgg cggtgctcga cggcgacgcc gccgtcaaca tcatgcaggc
    11701 gcgcggcccg gccgaggtcg cggcgtacaa ctggctgggc cggcgcacgc cgctgcacgc
    11761 cacggccagc gggaaggtgc tgctcgcggc gatgccgacg gccgtgcggg agagcctgct
    11821 ggcgcgcgag cagcagcggt tcaccgcgcg cacggtgacg gcgcccgcgg cgctgcgggc
    11881 ggcggcggac gaggtggcgg ccgaggggtt cgcggtcacg cgcgaggagt tggaggccgg
    11941 cctgaacgcg gtcgcggcgc cggtccgcag gtacgacgga acggtcatcg gggcgatcgg
    12001 cgtgtcgggt cccgtgtacc ggatgggcga ggaacggctg tccgagctgg ccgaaagctg
    12061 cacctcggcg gcgggcgagt tgtcgcggcg cctcggcttc ggcagctgac acgcgaacgt
    12121 cccggcgctt ttacgccccg gtgatccgcc gcccttgaca ccgcgagtgg ccgttctcac
    12181 catgtcccac atggcgcaac ccagcgcgcc atgcgcaacg cgtcggtggg aggagcgggc
    12241 catggcagcg agggcggaca cgcgcgtcgt catcatcggc gcgggcatcg tcggctgcgc
    12301 gctcgccgac gagctgaccg cccgcggcct gcgggaggtc acggtgctcg accggggccc
    12361 gctgttcgcc gggccgggct ccagctacca cgcgccgggc ctggtgttcg ccaccagtcc
    12421 ggccaaggtg ctctccgact tcgcccgcta caccatcgac aagtaccggt cgctcggctg
    12481 cttctcgccg gtcggcggcc ttgaggtcgc caccacgccg gaacgcctcg cggacctcgc
    12541 gcgccgggcc gggctcgccg cgtcctgggg catcgaggcc gaacgggtca gcgcgcggcg
    12601 ctgcgccgaa ctgtggccgc tgctcggcgc ggaccgcgtg ctcggcgggc tgcacacgcc
    12661 gcgcgacggc ctggccgacg cggccctggc ctgccgcctc caggccgaac gcgcgatggc
    12721 gcgcggcgcg acgttccacg gcgggcacac ggtgaccggc atcgaacgcg gcccggacgg
    12781 cgcggtggtc gcggtgcgca ccgaccgggg ggactttccg gccgacgcgg tggtctcggc
    12841 cgccgggttc tgggggccgg tcgtcggtgc gatggccggg gtgccggtgc cgctgctgcc
    12901 gctggcccac cagtacgcca ggaccggccc ggtacccggg ctcgacccgg acgcgcggct
    12961 gccgatcctg cggcaccagg accgcgacct gtacgtgcgg cagcacggcg acgccctcgg
    13021 catcggctcc tacgggcacc ggcccatgcc ggtcgacccg ttcaccctga ccgcgtcgga
    13081 actgccattc agtgcggagg agttcgcgcc cgcctggcgg gacgcggccg agctgttacc
    13141 cgcgctcggc ggtcccgggc cggcgagcgg gttcgacggc gtgttctcgt tcacgcccga
    13201 cggcatgccg ctgctcgggc aggtccgcga ggtgccgggg ctctggctgg ccgaggcggt
    13261 gtgggtgacg cactcggcgg gcgccgcccg cgccgtcgcg cagtggctgg ccgagggcag
    13321 gccggccacc gatacgcacc tgtgcgacgt gcaccggttc accggcgccc agctctcgcc
    13381 cgcctacgtc gcggaccggg gggcgcagag cttcgtcgag gtgtacgaca tcatccaccc
    13441 gctcgacccg cccgcgcggc cgaggccgct gcgggtcggg ccgttccacg tgaaacatcg
    13501 cgaactgggc gctcaccagc tggaatacgc cggctgggag cgcccgcagt ggttcgaggc
    13561 gaacgcgccg ctggccgagg cgctgccgcc cggcgccgtc ccgccgcgcg acgcgtgggc
    13621 cgcgcggcac tggtcgccga tcgcggcggc cgaggcgctg gccacgcggg aacgggtcgc
    13681 gctgttcgac atgacgccgc tgacccggct tgaggtcacg ggcccgggcg cgctcgcgtt
    13741 cctgcgccgc atgaccacag ggcgcgtgga ccgcgggccg ggctcggtcg gctacgcgct
    13801 gctgctcgac cacgcgggcg gtgtgcggtc cgacatcacc gtcgcccggc tggcccggga
    13861 ccactggcag atcggctgca acgggcccct cgacctggac tggctcctgc ggcacgcgcc
    13921 gacggacggc tcggtcgccg tccgcgacat cacgccgggc acctgctgcc tgggcgtgtg
    13981 gggcccgctg gcccgcgagc tggtcgcgcc gctggccgac gcggacgtct cgcacgaggc
    14041 gttcggctac ttcaccgcgc gccggctgca catcgggcac gtcccggtga cggccatgcg
    14101 gctgagctac gtcggtgagc tgggctggga gctgtacacc acggccgacc tcgggccgct
    14161 gctgtgggac accctgtggc gggccgggca gcgcctcggc gtgctcgccg cgggccgcgc
    14221 cgcgttcacc agcctgcggc tggagaaggg ctaccgggcc tggggggtcg acatgaccac
    14281 ggagcacgac ccgtacgagg ccggcatcgg cttcgccctc cggcccggtg accgcgactt
    14341 catcggcggg gccgcgctcg cgggccgttc ggaggcgacg gcgcggcggc ggctggcgtg
    14401 cctcacgctc gacgacccgg cggcgatcgt cctgggcggc gaaccggtgt acgcggccga
    14461 cgagcccgcg cggcccgccg ggtacgtcac cagcgccggc tacgggcaca ccgtcggccg
    14521 cgccatcgcc tacgcctggc tgccggccgc cctcgccgtg ccgggcaccg gcacgcacgt
    14581 cgcctacttc ggcgaacggc tcgccgcgac cgtgcgcgcc gagccgctgc tcgacccgga
    14641 gctgtcccgc atccggcgct gacgcccggc ccggccgtcc caccgcccgg ccgggcgcgg
    14701 gagggtgaag gaggaggaac acccgagaac ggagagacat ggcttccgga tacgacgtca
    14761 tcgtgctggg cctgggcggc atgggcagcg ccgccgccga ccacctggcc gcgcgcggcg
    14821 cccgcgtgct cggcctcgaa cagttcggcc cggtccacga ccggggttcc agccacggcg
    14881 gctcccgcat cacccggcag tcgtacttcg agggccccgc ctacgtgccg ctgctgctgc
    14941 gcgcctacga gctgtacgaa cggctcgcgc gggacgcgga ccgcgagatc gcgctgctgt
    15001 gcggtgggct gatgatcggg cgccccgaca gccgcaccgt ggccggcagc gtccgctcgg
    15061 ccaccgcgtg ggacctgccg cacgagatgc tggacgcgcg cgagatccgc gcccggttcc
    15121 ccacgctcgc gccggccgac gacgaggtcg cgctgttcga gcggcgggcc gggctgctgc
    15181 gccccgaggc gacggtcgcc gcacagcttg agctggccgc ggcggcgggc gccgagctgc
    15241 gcttcgagga gccggtcacc gcctgggagg cgctgcctgg cgggcgcggc gtccgcgtca
    15301 ccacgccgga cggcgtgtac accgcggggc acctggtggt ctgccccggc gcgtgggcgc
    15361 cgcgccagct ggccgacctc ggcgtgccgt tcaccgtcga gcggcagatc atgtactggt
    15421 tcgaacccga gggcggcacc gcgccgttcg agccggaccg gcaccccgtg tacgtgtggg
    15481 aggcccccga gggcacgcag atctacggct tccccgcgct cgacggtccc ggcggcggcg
    15541 ccaaggtggc gttcttccgc cagggcatcc cctgcacccc ggagacgatc gaccgcacgg
    15601 tgcacccgga ggaggtggcc gagatggccg cgttcgccgg ggcgcggctg cccgccctgc
    15661 cggggcggct gctgcgggcg gtcacctgca tgtacaccac gactcccgac gagcacttcg
    15721 tgatcgcccc gcacccggcg cacgcggcgg tcaccgtggc ctgcggcttc tccgggcacg
    15781 gtttcaagtt cgtccccgtc gtcggcgaga tcctcgccga cctggccctc acgggcagca
    15841 cgccccaccc catcgagctg ttcagcccgg gccggttggg aggccggcag acatgacgac
    15901 gacgccgatc accgcgaccg ggctgcttcc cacgctgccg ggtcccgcgt acaccgaccc
    15961 cgagacgttc cggcgcgagc aggaacggat cttcgaggcg cgctggttct gcgccgtgcg
    16021 cgccggcgac ctgctgacgc cgggctcgtt ccgcaccgtc accgtgggcc gcgagaacgt
    16081 gctggtcacg cgcgggcgcg acggcgcgct gcgcgcgttc ctcaacgtgt gcaggcaccg
    16141 gggcgcccgg ttgtgcaccg aggagtcggg gcaggtgcgg cgcaccttcc gctgccccta
    16201 ccacgcgtgg acctacgcgc cggacgggcg gctggtggcc gcgccgaacc tcaaggacct
    16261 gccgggcctc gaccggtccg cccacggcct gatcggtgtg gcgctgcggg agtggctcgg
    16321 ctacgcgtgg gtgtgcctcg cggacgagcc gccctcgttc gacgaaacgg tcatcggctc
    16381 ggtcagcgcg cgcctgggcg acgaccgggc cgtcgaacgc taccggcccg ccgacctcgt
    16441 gctcggccgc cgcgtcacct acgacgtgcg ggccaactgg aagctgatcg tcgagaactt
    16501 catggagtgc taccactgcg ccaccatcca ccccgaactg gtgcaggtgc tcccggagtt
    16561 cgccgggggc tgggcggcgc aggccgccgt gggccacggg gccgcgttcg cgccggacgt
    16621 ggagggcttc accgtggacg gcagcggcgg cttcggccgg ctgcccgggc tcgccgatga
    16681 gcaggaccgg cgctacttcg cgaccacgat caggccgcag gtgttcgtca acctcgtgcc
    16741 cgaccacgtg atcgtgcacc gcatgttccc gctggcaccc gaccggacgc gggtggagtg
    16801 cgactggctg tacgcggccg acgtgatcga cggcggcgcg gacgtgtcgg cgtccgtcga
    16861 gctgttccac cgggtgaacg agcaggactt cgcggcgtgc gaacgcaccc agcccgcgat
    16921 gcactcgcgc gcctacgcgg cgggcggcgt gctggtgccg accgagcacc acatcaccga
    16981 gttccaccac tgggtgacct ctctgctggc ctgaccgggt gccggtccga ccgggcgcga
    17041 ggccgcgggg ccgggcggtg gcctctggtc gtgtgatggt gtgatgtccc ggtggaggcc
    17101 cccgtagccg tgaacgccga ggagcgcgcc gaggagcgcg cggaacgccg ggcccgcgcg
    17161 gcgccgcgcg ccggccgccg cgcggcgtgg ccgcgcctcg ccctgctggc gctgctgctc
    17221 gcgctcgcgg ccggcgcggc gttcgcggcc ggcggcgacg cggtgccggg cacgggctcc
    17281 tggccgctgt tcgtcgccgg gtacgcgctc ggcacgctgg cgttcgtgcc caaacccgcg
    17341 ctcacggcgg cggcgggcgc cgcgttcggc gcggtgtccg gcatcgcggt cgccgccgcg
    17401 ggcaccgcgc tcggcgcgct gctcgccttc ggcgcggcgc gcctgctcgg ccgggacgcg
    17461 gtgggcccgc tgctgacccg gcaccgggcc acggccgcgc tcgaagaacg gctggcgcgg
    17521 cggccgttca ccggcgtgct cgtgctgcgg ctggtgccgg tcatgccgtt cgccgcggtc
    17581 aacctcggcg cgggggtgtg ccgggtgggc tggctgccgt tcaccgcggc gaccctcatc
    17641 ggcacgctgc cggggaacgc ggcctacgcg ctcgcgggcg ccgccgcgac cgccccggcc
    17701 tcgcccgccc tgtggtcggc cgccgcggtg gcgctcgcgc tgaccgcctg cgccgccctg
    17761 tggcggcgca ggcggctgcg cgcggccggc tgaccgcgcg ccgtgcggca gtcggccggt
    17821 cgggtcgccg gccgccaggc cggacccggt gaccccggcg accggacgca ccggccggac
    17881 ctggcggacc tggccggacc cggccaaccg gccacccggg cgcgtccgtt gaagccggcc
    17941 aatccggccg ggacgcgctc cgggcgatcc agccgacacc ggccaaccgg ccgcccgggc
    18001 cgtcccaacc aaccgaaccc ggcgccccgg cccaagcggg cccgcccggc caaccggccg
    18061 cccgaccccg gcgcccaacc agccgcccgc ccgggtcagg cgcccgagcg gggtcaggcg
    18121 ccccgcaggg cgctgcgcag cggcgcgagc cggcgcaccg gccgggcgcg cgcgctgtag
    18181 cgcagcatca tgtcccggcc cgcgggggcg ggttccgacc gctgctccgg cgcgccgagg
    18241 gcgagcgcga ggcggaacag cggcgcgaca cgcagcacgt ggcggccgtc ccggggaagc
    18301 ggcgtgagca tgtggcagtc ggccagcagc tcgaccgagc gttcgatcga gccggccgag
    18361 cggtgcaggc ggcgggccag gtaggccacg gtgacgtccg tctcctccgt cctgctcagc
    18421 tccgtcagca cctcgcgcgc gccgcgcggc agccgggcgg ccgactggat caggtagcgg
    18481 cggacgttca ggtgcgggct gctcagctcc tcaagccgct gccgctcgtc gtcgagccgc
    18541 gcggcgaagt ccgcgaggcc gcggctcggc caggcggcga tccggctgcc gacggcccgg
    18601 atcgcggccg gcatcccctc gcaccgggcc gcgacggccg ccgcggcctc gggttcgcgg
    18661 cccgcgcgct cggcgcccac cacccgggtc agcagccgca gcgcctcggg ctgcggcatc
    18721 ggcccgagct ccacgggggt caccgcgccg ggcagttcgg cgaaccggca gcgcgaggtc
    18781 acgatcacga cgttgtcggc gcccgcaggc agcagcggca gcacctggtc gctgcccgcc
    18841 gcgtcgtcga gcagcagcag gaagcgccgg gccgcggccc agccgcggaa catcgccgcc
    18901 aggtcgtcgg cccggtgcgg cagggagcgc cggtcgaacc cggcggccgt cagcagccct
    18961 tcgagcgtct ccgccgggtg ccgcgcggcg ccgtcctcgc cgtgcaggcg cacgccgagc
    19021 tggccgtcgg ggaagtcccc ctggaggcgg tgcgccacct ggagcgcgac ctcggtcttg
    19081 cccacccccg ggccgcccgt gaccgtcacg atgcgcaccc cggacgagga gccgacgccc
    19141 cgcaccgcgc gttcgacccg gtctatctca ccgcggcgcc cgacgaagtc gcgcagcgca
    19201 ggcggtagtt ggaacggcgc cgcggccggg cgcgcggggc gtgcgcgcgg gcccgcgggg
    19261 gcttccgcgc gccgttcctc cccggtcagc gccccccgct ggagccgttg cagccgctcc
    19321 gacggttcga ggccgagctg ttccaccatg gcccggtgca gccgggcgta ggcggcgagc
    19381 gcctcgccgc gctggccgca gcgttcggcc gccatcatga gctgggcgca gaactcctcg
    19441 tgcagcgggt gcgcgtaggt gaggtccctg atctcctcaa gcagcgagtg gtgcaggccc
    19501 cgcgcgaggt cggcggcgat gcgctgctcc agggcgcgca gccgcaggtt ctccagcttg
    19561 gcggcctggg cggccaggac gggccccatc tccacgtctt cgagcgcggc gccgcgccac
    19621 agttcgaggc cgcgccgcag cgcctccgct ccgtcgctcg cctggccgcg ccccagcgcc
    19681 tcgcgcccct ggcgcaggga ctcctggaac tcgctcagat ccagccggcc gccgccgagc
    19741 gagagccggt agccgtgcgc gtgccgctcc accgggcccg ggtcccgggc cgaaccgccg
    19801 tcgtcgctga gcagcttgcg taactggtag atgtaggtct ggacggtctt gcgcgcccgc
    19861 atgggcgggt gctcccccca cagctcgtcg atcagcagtt cggtgggggc cacgcggtcc
    19921 acgtgcgtca ggagcacggc gagcacccgg cgggccatgg gcgcgctcgg cgttctcagc
    19981 tgtccgttga cgcggatctc catcggcccc agcagggcag actgcaacat ggcaacgtcc
    20041 ttatcggtca tgggctccgg ttaccgacga cgcgacgcgg tccgcgggtt ccgcggacgg
    20101 gcacgcgccg cacggtggcg gaccctcgcc gtgcgcgcgg ccgttgacgg gcgctgcccc
    20161 ggtcgcgcac ggctcgtggc tggtgccttg ccgttcaagg aggacgggcg cccggcacgg
    20221 gcccttgggg ggccggggcc cggtgccggg tgcccgtcgg gtcacgcgtt ccgctcagtc
    20281 gtccgcgcgc ggggagagcg cgtgccggaa cacgccgcgc gggtcccact tcgccttgat
    20341 ctcgcgcagc cgcgcggcgt tgcccaggta gtacaggtcc tcccacggca cgcccgaggt
    20401 gttccactcg gggtcggcca tgtccgtgtc ggggaagttg atgtagcagc cctcgtggtc
    20461 atcgcccggc accggcacgc cgccgctctt ggcgtacagg tcgcggaaga ggcgccgcat
    20521 ccagtccacg ccggcggcgt cgtcggccgc gtcctgccag gtgttcatga ggaacacctg
    20581 gatcacggag ccgcgctggg cggacgcggt ggcgtcgggg gccaccgcgt tgacgcgccc
    20641 gccgtaggac tggagcgcca ccaggctcgt gtcgtggccg tggtcgccgc tgtcgaggta
    20701 gtcgtacagc gtgtcggcct cggcctcgtc gtaaccgcgc cgcaggaacg ccgacttgac
    20761 cttctgcctg ccgatctccg cgtcctggga ctgggccagc gcctgcttgg cgtccagcca
    20821 gggcagcacc tcggcgggca gcacggcagg gaagtcgccg agccccgccg tgaggtgggc
    20881 gatgtagtcg tccagaagcc gcgcggcgtc ggggcgttcg ccgtcgacgt gcgcgaagcc
    20941 gacggcgccc atcgaggcgt cgccgccctc gcggggcctg ccgagcagga cgaggccccc
    21001 gaacagggag gcgccggcgg agtcgggcgc gctgttcgcc tcgtgccagc tgccgtagtt
    21061 ggcgaccagg gtgcggaacg cggcgcggtc cagggcgtcg cggttgaaca ggacggtgcc
    21121 ggcgagcatg gtggccggcg gccggggcag cgccgtgcgg gggtcgtcgc ccgtggcgcc
    21181 gggggagcgg aaccagtagc gggtgacgac gccgaagttg ccgcccccgc cgccggtgtg
    21241 gg
//
