LOCUS       NZ_CP084541            22652 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces marincola strain SCSIO 64649 chromosome, complete
            genome.
ACCESSION   NZ_CP084541
VERSION     NZ_CP084541.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces marincola
  ORGANISM  Streptomyces marincola
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Strepomyces indimicinicus sp. nov., an antibiotic producing
            actinomycetes isolated from the marine environment
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 6629020)
  AUTHORS   Shi,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-SEP-2021) Key Laboratory of Tropical Marine
            Bio-resources and Ecology, South China Sea Institute of Oceanology,
            Chinese Academy of Sciences, 164 Xingang West Road, guangzhou,
            Guangdong 510301, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. V6.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 444.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_020410765.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 03:45:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,763
            CDSs (total)                      :: 5,689
            Genes (coding)                    :: 5,612
            CDSs (with protein)               :: 5,612
            Genes (RNA)                       :: 74
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 56
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 21 of 77
            Pseudo Genes (incomplete)         :: 60 of 77
            Pseudo Genes (internal stop)      :: 2 of 77
            Pseudo Genes (multiple problems)  :: 6 of 77
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 16:57:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1555034
            Orig. end                         :: 1577686
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP084541.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22652
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="11"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22652
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22652
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12652](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12652)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            406..1398
                     /locus_tag="LC193_RS06590"
                     /old_locus_tag="LC193_06590"
     CDS             406..1398
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010637596.1"
                     /locus_tag="LC193_RS06590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06590"
                     /product="ECF transporter S component"
                     /protein_id="WP_404819359.1"
                     /transl_table=11
                     /translation="MREQRAPRRASATRERPGAPARERRAAPVRLGPRSAAALVLVSAA
                     GVVAFGWPLLADSASGLAHSADAPWLFALLLPLLLAVVVATIADTGLDAKAVAMLGVLA
                     AAGAALRPLGAGTAGLQPMFFLMVLSGRVLGPGFGFVLGGVSMFASALLTGGVGPWLPF
                     QMLSMGWLTMGAGLLPGAHRLRGRAELALLAGYGALASLAYGLVMNLQGWPYLAGMSSG
                     ISFVPGDPLPDNLARYAAYVATTSLGWDVPRALLTVVLILLCGGSVLRALRRATRRAAF
                     EVPARFEAPGPSEAPGPGEPTAGDEASGHEGASRHEGAQGPGEAPAHPA"
     gene            complement(1409..2365)
                     /locus_tag="LC193_RS06595"
                     /old_locus_tag="LC193_06595"
     CDS             complement(1409..2365)
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.5"
                     /locus_tag="LC193_RS06595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06595"
                     /product="peptidoglycan-binding protein"
                     /protein_id="WP_226072488.1"
                     /transl_table=11
                     /translation="MTIDRSECLICGRPVLPTGEPDCECWTHSLSRPVEPPLHGPDPAD
                     VALFPVDASAPGRRQVPTGAPRAARAPGSRPAPSVPQRPTGTHRKPRGRTRIATAAGGA
                     VAAVVGCTALAASILSGQGRQEQAHEPDGAGPSLAQPDGGDARPDPPPPPAPDREGADA
                     APGPGPADPERSEPEGGEGTADSERTESAPPDEEPSEPPSADRPEPDPVDPEPTPDAPP
                     APGPETPATPEPPAPSEPPAGAGPVLGAGDEGPEVAELQRRLLQLNWLYHGEAHGRYDE
                     QTAAAVARFQVAYGVRGDPEGLYGPQTRRALEQHTRL"
     misc_feature    2744..2762
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.75"
                     /tool="antismash"
     gene            2892..3581
                     /locus_tag="LC193_RS06600"
                     /old_locus_tag="LC193_06600"
     CDS             2892..3581
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008739089.1"
                     /locus_tag="LC193_RS06600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06600"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_226072492.1"
                     /sec_met_domain="HAD_2 (E-value: 1.9e-20, bitscore: 72.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPLTLTARALLLDMDGTLVNSDAAVERVWRTWAEMRDVDPVRVF
                     AIMHGRQARATMADLLPERPVEEHEADAAWLLARETADTEGVVPIPGAGAFLDAIEHAP
                     HALVTSADSGLARARMSAAGLRMPEVRITAESVSASKPDPEGFLKGAAELGIAPADCLV
                     FEDSAAGIEAARAAGMRVIGVGLRAASLAPTAYAATLENVRVEAAPRPRPEGFPPSDGL
                     IRLTVRP"
     gene            complement(3714..4283)
                     /locus_tag="LC193_RS06605"
                     /old_locus_tag="LC193_06605"
     CDS             complement(3714..4283)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006801 - superoxide metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660729.1"
                     /locus_tag="LC193_RS06605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06605"
                     /product="superoxide dismutase family protein"
                     /protein_id="WP_226072494.1"
                     /transl_table=11
                     /translation="MKILATGAVAMTAVLATAGSSVAAGQDDVLLYDAGRFAPLGAGAG
                     AVPKAVTYNEELVPAGSEIHVAQGIRGNSMLIDIATLGLDPGHTYGTHVHTEPCGADPA
                     DAGGHYQNEQGVVDEDSEVWLDFTVDERGVGQAEVHKNWLFRAGEAGSLVLHERGTSEG
                     HDEHPPGDAGARVACFSIPFAGVPAA"
     misc_feature    4275..4290
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.81"
                     /tool="antismash"
     misc_feature    complement(4434..4449)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.86"
                     /tool="antismash"
     gene            4484..5143
                     /locus_tag="LC193_RS06610"
                     /old_locus_tag="LC193_06610"
     CDS             4484..5143
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018556421.1"
                     /locus_tag="LC193_RS06610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06610"
                     /product="DedA family protein"
                     /protein_id="WP_226072497.1"
                     /transl_table=11
                     /translation="MQETLGILLYAPWIYVIVAASILLDVFVPFLPSGVLVVTAATAAA
                     GTAADVAGLPTPGPDQALPHLLLLVLCATTASVVGDLLAHRLALRGGRRFDSAIARSRR
                     LDAAQQRLATALRGRGGGPLVVLARFAPAGRAVVSLGAGVARRRTREYLPWSALAAVVW
                     TGYSVGVGYLGGHLLGVSWLSTGLSLIALIGAGFVAARLLRPSPAAETPAAVPQAP"
     misc_feature    complement(5197..5212)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.28"
                     /tool="antismash"
     misc_feature    complement(5217..5232)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.49"
                     /tool="antismash"
     misc_feature    5218..5231
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.39"
                     /tool="antismash"
     gene            5530..6132
                     /locus_tag="LC193_RS06615"
                     /old_locus_tag="LC193_06615"
     CDS             5530..6132
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="LC193_RS06615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06615"
                     /product="response regulator transcription factor"
                     /protein_id="WP_226072500.1"
                     /transl_table=11
                     /translation="MIRLLFVHDDTLLRCGLTSLLGAEVDIEISSLSWEALTRAEPPPP
                     GTVRLADVTCPGFARYADETVRQTGAEDEHGLVVLAPAGRPGLLTRAFEARALGYVSKE
                     APPQRLLDAIRAVAKGGRYVDDALAYDFLSASRMPLTPRELRVLALAADGAPVPEIAGE
                     LWLAEGTVRNYLAAVIRKTGARNRVDAIRIARSAGWV"
     misc_feature    5539..5541
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6019..6021
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6019..7944)
                     /locus_tag="LC193_RS06620"
                     /old_locus_tag="LC193_06620"
     CDS             complement(6019..7944)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655806.1"
                     /locus_tag="LC193_RS06620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06620"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_226072502.1"
                     /transl_table=11
                     /translation="MRDHAVFRYLRRNRRPLAVLAAWGLLPAAQTFLLGYGLARALDDG
                     FLAGRTGVGLAWLAAAGGGVLAGAFGTARVHRAVGALAEPLRDGLVREVVARGLHRAVR
                     AGRPESGTADVSRLTHQVEIARDSFAGLVLVLQMFVCTLAGSLAGLASLAPVLLPVVLG
                     PLLLALALFAWSLRPLARRQRAVLVADEALADAFGETAGGLRDITAAGVRGRAEAAVGA
                     RVDAELAAALALGRWGAVRVVALGIGGQLPVLLLLFLGPWLLRNGVTPGGLLGALTFVT
                     QALLPALQALLGGVGSAGTRLAVVIARLRTDPLPPQGPPAESARERAGAAVEPSGSVVE
                     PSGSAPAERAGPAPAREARAPGVGAARRRPAVELRGVTFAYGGRADPVLDGLDLAVPPG
                     GHLAVVGPSGAGKSTLAALAAGLLAPRAGRVALCGRPVAGRTAAELAALRVLIPQEAYV
                     FRGSVADNLSYLRAAPPPAAALTAAAEAVGAGDLLDRLGGPAGQVDPAALSAGERQLLA
                     LTRAFLSPAPVALLDEATCHLDPAAEAGAERAFAARPGGTLVVIAHRISSARRADRVLV
                     LDGAEAHSGTPRELLDRSALFRDLAAGWSDPARAPGDADGVDAVAGPGLADDGGQVVAH
                     RALREP"
     gene            complement(7937..9706)
                     /locus_tag="LC193_RS06625"
                     /old_locus_tag="LC193_06625"
     CDS             complement(7937..9706)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569990.1"
                     /locus_tag="LC193_RS06625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06625"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_226072504.1"
                     /transl_table=11
                     /translation="MPTHLLDPTLRATARQGAGRMAVLFALSLAAAGVALALPTALGRA
                     LDALLAEGDAAGGPALLTAGLVIAQVLVGVLTTVLTAGADAHGAAWLRGRLLRHLLAAG
                     PGAAARFPEGDLVARATGNAVHAGAAPAALAAAFAAAATPLGAIVALAVTDARLALVFL
                     AGLPLLALLLRAFARSAGDAFAGYQRAQADIAGRLVDALRGARTIAAAGTEEAERRRVL
                     DPLPRLGEHGLRMWRVNARATGRAAALTPLLQLAVVATGGLLLAVGDLTVGGLLAAARY
                     AALAGGVGLFVGHLNRLVRARAAAVRVGEVLAVPPQRHGGAALPPGGPGRVEFRGVSAR
                     RGGREVLRGLDLVVPGGSTVALVGRSGAGKSLLAALAGGLAEPDAGRVLIDGVPVTDLA
                     PDALRAEVGYAFERPALLGGTLAPTVAATIGLGPGPAPPPERVAAAARAARADGFIRTL
                     PAGYATRCDGVPLSGGELQRLGLARAFARGGRLLILDDATSSLDTVTELHVARALAAHT
                     AARTRLVVAHRAGSAARADLVAWLDEGRVRALAPHGELWARADYRALWAADEPARGEAA
                     GTSEARAGGAAGA"
     gene            complement(9797..9928)
                     /locus_tag="LC193_RS06630"
                     /old_locus_tag="LC193_06630"
     CDS             complement(9797..9928)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016471140.1"
                     /locus_tag="LC193_RS06630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06630"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_226072506.1"
                     /transl_table=11
                     /translation="MSLLDLQSMEPEVATGGGGEGDLSSLSLLICDTHSSNSVILCL"
     CDS_motif       complement(9869..9928)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSLLDLQSMEPEVATGGGGE"
                     /locus_tag="LC193_RS06630_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9797..9868)
                     /prepeptide="core"
                     /locus_tag="LC193_RS06630_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="14.60"
                     /molecular_weight="2264.6"
                     /monoisotopic_mass="2263.2"
                     /core_sequence="GDLSSLSLLICDTHSSNSVILCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSLLDLQSMEPEVATGGGGE"
                     /leader_location="[9868:9928](-)"
                     /alternative_weights="2282.6"
                     /alternative_weights="2300.6"
                     /alternative_weights="2318.6"
                     /alternative_weights="2336.7"
                     /alternative_weights="2354.7"
     misc_feature    9935..9949
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.04"
                     /tool="antismash"
     gene            complement(10001..12652)
                     /gene="lanKC"
                     /locus_tag="LC193_RS06635"
                     /old_locus_tag="LC193_06635"
     CDS             complement(10001..12652)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359194.1"
                     /locus_tag="LC193_RS06635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06635"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_226072508.1"
                     /sec_met_domain="micKC (E-value: 1.8e-230, bitscore: 765.7,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 8.3e-09, bitscore: 33.5,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVFCLVDRHFYEAPERAASRDAAGSGQEGLYETARRPVPQ
                     GWLSERFGDWLHLQPRDGITPPQGWKIHVSACLDNADKTAAKVWDYCVPRRIPFKFVPS
                     AHLLFLRNSKYAGRHSSGKFVTIYPADEAALRTVLTDLGDQLAGEPGPYILTDLRWERG
                     PLYVRYGGFVPRYCDDGTGAVVPAIENAEGRLVPDRRGPAFGVPAWVTLPPFLAPHLAA
                     RNEVTVAELPYRIDSALHFSNGGGVYRGTDTRTGDAVVLKEARPHAGLAADGADAVTRL
                     EREKAALDRLAGLAVAPGVRDWLTVGEHRFLVMDHVPGRTLNAFFAERHPLLATDPAPD
                     AVASYTRWALAVHRNVERAVAALHGRGLVFNDLHMYNIMVAPDETSVTLLDFEAAAPAE
                     DGARQVVAHPGFIAPADRTGFAVDRYALACLRLALFLPMTTLFAVDRDKAAHLARVARR
                     EFPDVPAAFFDEAVAEIEGREDRNARKRPAAPPEPGDWPAARASMARAILASATPERED
                     RLYPGDIAQFGPGGGLGLAHGAAGVLYALAETGAPRHPEGERWLLRRAADPPRNTPLGL
                     YDGLFGVVHVLHRLGHTEAALGLATRALGEGWERLPAHLHGGLAGIGLVLDDLAADTGN
                     PALAVHAGRAAELAARHVAGPAEPRGHRRAGLLHGATGVALLFLRRYERTGEVRLLATA
                     AAALRRDLAHCRADRSGALLVDEGDRLMPYLGEGSVGIAAVLDDYLAAASSAGLPAEED
                     LARAAADILPAARLRYYAQPGLFRGRAGMIWHLARTAARPAPPGRRPGPEPEAALAAQI
                     DALGWYAMAYDGELAFPGEQMMRLSMDLGTGTAGCLLALGTALHRPGDPAGLPRLPFLP
                     HPRHPKARPPSA"
     gene            complement(12753..13553)
                     /locus_tag="LC193_RS06640"
                     /old_locus_tag="LC193_06640"
     CDS             complement(12753..13553)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088388.1"
                     /locus_tag="LC193_RS06640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06640"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_226072510.1"
                     /transl_table=11
                     /translation="MNGDSPVVPRTDRPHSARMYDYLLGGRDYYAADSQAAENALAAAP
                     TLRIAAQENRKFIARAVRHLVLDVGIRQFIDLGPGLPTTENVHQVAQEADPEARVVYVD
                     NDPIVLAFGGAMLEQNERTTVVHGDIRDPLAVLHHPRTREQIDPDEPVGVLAVAVLHFI
                     RDEDDPAGIVRALADVLAPGSHFVLSHGTADISPQAAMGVQAAYRSHGVPLTLRSKERF
                     GEFFTGLELIEPGIQIVSEWRATEPEAERPSCEDVSWYGGVGRL"
     tRNA            complement(13903..13976)
                     /anticodon=(pos:complement(1568974..1568976),aa:Met,
                     seq:cat)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LC193_RS06645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="LC193_06645"
                     /product="tRNA-Met"
     gene            complement(13903..13976)
                     /locus_tag="LC193_RS06645"
                     /old_locus_tag="LC193_06645"
     gene            14154..14690
                     /locus_tag="LC193_RS06650"
                     /old_locus_tag="LC193_06650"
     CDS             14154..14690
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957981.1"
                     /locus_tag="LC193_RS06650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06650"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_226072512.1"
                     /transl_table=11
                     /translation="MRPVSRTSERLLLRELTVDDVDDVHAIYGDATATEHLSFEPRSRD
                     QVAHIVARSMVSAFATPREEYALAVCERAGARLVGYARLAMDPHGQRAATIGFALRPDV
                     WGAGYGTELVRALVALGFEDLGLHRLWAARAPENSASRTVLDRAGLVEEGRIRHHVHVR
                     GAWRDSVVHAIVNGT"
     gene            14972..15238
                     /locus_tag="LC193_RS06655"
                     /old_locus_tag="LC193_06655"
     CDS             14972..15238
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (33-73). E-value:
                     0.0014. Score: 11.4. Matches aSDomain:
                     nrpspksdomains_LC193_RS06655_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975561.1"
                     /locus_tag="LC193_RS06655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06655"
                     /product="hypothetical protein"
                     /protein_id="WP_226072514.1"
                     /transl_table=11
                     /translation="MATRKITVSVPEELVESIKERVHPRGVSAYIAAAAAHRDAMDRLR
                     ELAERLEEEHGAVTADEEREAHARIAAIDDWHDEQRSRPGGAA"
     aSDomain        15071..15190
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_LC193_RS06655_PKS_Docking_Cterm.
                     1"
                     /evalue="1.40E-03"
                     /label="LC193_RS06655_PKS_Docking_Cterm.1"
                     /locus_tag="LC193_RS06655"
                     /protein_end="73"
                     /protein_start="33"
                     /score="11.4"
                     /tool="antismash"
                     /translation="AAAHRDAMDRLRELAERLEEEHGAVTADEEREAHARIAAI"
     gene            15235..15681
                     /locus_tag="LC193_RS06660"
                     /old_locus_tag="LC193_06660"
     CDS             15235..15681
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028878.1"
                     /locus_tag="LC193_RS06660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06660"
                     /product="hypothetical protein"
                     /protein_id="WP_226072515.1"
                     /transl_table=11
                     /translation="MSRTARGRQDHARKRVFVFDSKALSEAVRGGREVTALIKTASRLN
                     IPVITSALTTVAAWDPRGTSRQAPWHWTLSRVRVVHTDDQVIATAREMLRAAGLHGHKY
                     AIDAVLAAVAGREAAQGAQATVFTSDTDDMSRLLAGRSVRVEKV"
     misc_feature    complement(15843..15857)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.78"
                     /tool="antismash"
     tRNA            complement(15860..15931)
                     /anticodon=(pos:complement(1570931..1570933),aa:Val,
                     seq:tac)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="LC193_RS06665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="LC193_06665"
                     /product="tRNA-Val"
     gene            complement(15860..15931)
                     /locus_tag="LC193_RS06665"
                     /old_locus_tag="LC193_06665"
     gene            16065..17432
                     /locus_tag="LC193_RS06670"
                     /old_locus_tag="LC193_06670"
     CDS             16065..17432
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014045741.1"
                     /locus_tag="LC193_RS06670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06670"
                     /product="hypothetical protein"
                     /protein_id="WP_404819521.1"
                     /transl_table=11
                     /translation="MAIHLRGVEHVTATRTAKQLAALLLLPPLSLAAVAATLPGSFTGG
                     GTRRWGRGRVEDLRAEAQEAKDAAAAAFYALDTAQRDLRITVETITAADDTREAARAAA
                     EFAAFGERIDRVSHAYITTMDAHDLDGEGLDAGAATRARQELRGARDELDRTRRDLEAF
                     GQSIGPLLERAESQLAQVAPAVERARQALRAATEALDAARAAGFGAGDLAASLAALGPE
                     LRRLNEGAGQHGVQPTIRRAEDVRRRAEAVAADAARLPQRAAEIDRRLSSLRTRAEAIV
                     TRAGKVEPVLSELRRRFSMACWQDLQRVPEQAAQSVRQAEQILDEARRARDEQRFEDAT
                     TRLTTVHALLGRTDEAVSAAGERLRRLNEVSFDPRKEIDRTRFVLRDAQRLAMAGRSVP
                     EPRHARPLDAAVERLDRAVARLESGGRHPDYWEFLTEMDAVRSAVAAVVEEIRAGR"
     gene            complement(17429..18001)
                     /locus_tag="LC193_RS06675"
                     /old_locus_tag="LC193_06675"
     CDS             complement(17429..18001)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047513.1"
                     /locus_tag="LC193_RS06675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06675"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_226072517.1"
                     /transl_table=11
                     /translation="MTDADQLTPGARRILDVASELFYQRGIHAVGVDTIAAESGVTKRT
                     LYNRFGSKDALVVAYLQTRDRRWRDLVTARLDATPDDPVRRVLVPFDVLPEWVSESERG
                     CSAVNAFAELPEPDHAGRRVVVAEKQWLHELFLRLLTEAGARSAATLATQLLSLHEGAI
                     VATSIAGAHDAAAAVHIAATALVEAAL"
     gene            18085..18297
                     /locus_tag="LC193_RS06680"
                     /old_locus_tag="LC193_06680"
     CDS             18085..18297
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="LC193_RS06680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="LC193_06680"
                     /product="hypothetical protein"
                     /protein_id="WP_226072518.1"
                     /transl_table=11
                     /translation="MHAIVRQLIEGTRAFGHGIAAGTAIRHSRTPGPATAAATAWTGKR
                     QGIGRPDGAAVPVGADQHHQAGAAR"
     gene            18343..19005
                     /locus_tag="LC193_RS06685"
                     /old_locus_tag="LC193_06685"
     CDS             18343..19005
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019433084.1"
                     /locus_tag="LC193_RS06685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06685"
                     /product="DUF4383 domain-containing protein"
                     /protein_id="WP_226072519.1"
                     /transl_table=11
                     /translation="MGTFTTSGSPRLPSTGPLGLLRRARLDEHLPVDRRLSRVYRIGAG
                     LVGLGLVVFGALGITQNLDMFSTGDDTIWSLNTNGALSWLSIVVGLVLFFGMVRGGNLA
                     STLNMLIGAAFVLSGFVNLALLETGANVLNFRMPNVIFSFAAGLLLMSFGMYGRVSGRL
                     PHDNPYWRVRHPEAGEDAPERQEHAEHGRRVLDERQREETARSASGAVHRGAPDRHG"
     gene            complement(19095..19841)
                     /locus_tag="LC193_RS06690"
                     /old_locus_tag="LC193_06690"
     CDS             complement(19095..19841)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006538516.1"
                     /locus_tag="LC193_RS06690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06690"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_226072520.1"
                     /transl_table=11
                     /translation="MDLPRIFTIRESSHRIHNPLTPDKLAALGQALRLPAGTRVLDLAS
                     GSGEMLCTWARDLGFTGTGVDLSTVFTEQARARAVELGVADRVDFVHGDASGHVADEPV
                     GLAACVGATWIGNGVAGTAALLSRSLSPGGLMLIGEPYWRRTPPSQEVAEACHATSLAD
                     FLPLPELIEQFGELGYDVVEMMLADQDSWDRYCAAQWLNLRRWLDLNPDDELAPEVRAE
                     LTTEPARYARFTREYLGWGVFALMQR"
     misc_feature    20258..20274
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.52"
                     /tool="antismash"
     gene            complement(20431..21288)
                     /locus_tag="LC193_RS06695"
                     /old_locus_tag="LC193_06695"
     CDS             complement(20431..21288)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010057510.1"
                     /locus_tag="LC193_RS06695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="LC193_06695"
                     /product="HAD family hydrolase"
                     /protein_id="WP_226072521.1"
                     /transl_table=11
                     /translation="MIPASTEATPDVTPGAPTVVASDLDRTLIYSAAALALGMPDARAP
                     RLTCVEVYQARPQSFVTETAGHLIAELAARTDAFFVPTTTRTREQYLRVNLPGPAPRYA
                     ICANGGHLLVDGRTDEDWHAAVLGRLAADCAPLAEVRDHLRRTADPAWLLRERDAEGLF
                     AYLVVDRALLPDTWAKELADWAGPRGWTVSLQGRKLYAVPRPLTKSAAVAEIVRRTGAG
                     SVLAAGDSLLDTDLLLAADHGWRPGHGELAAEGWGAPHVTALEGEGVGCGEEIVRAFLA
                     RLPG"
ORIGIN
        1 cggcgtgcgg gatgcggcgc acccgcgcga cctgtccgag gggcagcggc tggcgctagc
       61 gctcgccgtc gtgctggccg cggccccgcc cctgctgctg ctcgacgagc cgacgcgcgg
      121 cctcgactac gcggccaagg ccaggctggt gacctgcctg cgggaactgg cggacgaggg
      181 gcactgcgtc ctgctcgcca cgcacgacgt ggaactcgcc gcggaactcg ccgcgcgcac
      241 cgtggtgctg gcggacggcg aggtcgtcgc ggacgggccg acggccgagg tcgtgacggc
      301 ctcgcccgcg ttcgccccgc aggtggccaa ggtgctggcg ccggcgccgt ggctgaccgt
      361 cgcccaggtg cgggcggggc tcgaccggcc gacggacggt ggcgcgtgag ggaacagcgc
      421 gcgccccggc gtgcttccgc aacacgggaa cgccccggcg ccccggcgcg ggagcggcgc
      481 gccgcccccg tgcgcctcgg tccgcgttcc gccgcggcgc tcgtcctggt ctcggcggcc
      541 ggggtcgtgg cgttcggctg gccgctgctc gcggactccg cctcggggct cgcgcactcg
      601 gcggacgcgc cctggctgtt cgcgctgctg ctgccgctgc tgctcgccgt cgtggtcgcc
      661 acgatcgcgg acaccggcct ggacgccaag gccgtcgcga tgctcggcgt gctggccgcc
      721 gcgggggccg cgctgcgccc gctgggcgcg ggcacggcgg ggctccagcc gatgttcttc
      781 ctgatggtgc tctccggccg ggtgctgggg cccgggttcg ggttcgtgct cggcggggtg
      841 tcgatgttcg cctccgcgct cctgaccggg ggcgtcggcc cgtggctgcc gttccagatg
      901 ctgtcgatgg gctggctgac catgggcgcc gggctgcttc ccggcgcgca ccggctgcgc
      961 gggcgggccg aactcgccct gctcgccggc tacggcgcgc tggcgtcgct cgcctacgga
     1021 ctcgtgatga acctccaggg ctggccctac cttgcgggca tgagcagcgg catctccttc
     1081 gtgcccggcg acccgctgcc ggacaacctg gcccgctacg ccgcctacgt ggccaccacc
     1141 tcgctcggct gggacgtgcc gcgcgcgctg ctgaccgtcg tgctgatcct gctgtgcggc
     1201 ggcagcgtgc tgcgggcgct gcgccgtgcg acgcggcggg cggccttcga ggtaccggcg
     1261 cgcttcgagg cgccggggcc ttccgaggcg ccggggcccg gcgagcccac ggcgggtgac
     1321 gaggcgtcgg ggcatgaggg tgcgtcgagg cacgagggcg cgcaggggcc cggcgaggcg
     1381 ccggcgcacc cggcgtgaac gcggtcgctc acagccgcgt gtgctgctcc agcgcacgcc
     1441 gggtctgggg gccgtacagc ccttccggat cgccccgcac cccgtaggcg acctggaaac
     1501 gggccacggc cgcggccgtc tgctcgtcgt agcggccgtg cgcctccccg tggtagagcc
     1561 agttcaactg gaggaggcgc cgctggagtt cggccacctc cgggccctcg tcgcctgcgc
     1621 cgagcacggg cccggcgccc gcaggcggct ccgagggcgc gggcggctca ggggtggccg
     1681 gggtctcggg gccgggggcc ggcggcgcgt cgggcgtggg ctcgggatcg accgggtcgg
     1741 gctccggcct gtcggcggac ggcggctcgg acggctcctc gtccgggggc gcggactcgg
     1801 tccgctcgga atccgccgtc ccctccccgc cctccggctc cgaacgctcg gggtcggcgg
     1861 gccccgggcc cggcgcggcg tcggcgccct cgcggtcggg cgccggtggc ggcggcgggt
     1921 cggggcgggc gtccccgccg tcgggctggg ccaggctcgg gccggcgccg tccggttcgt
     1981 gggcctgctc ctgccgcccc tggccgctga ggatcgaggc ggcgagcgcc gtgcagccga
     2041 ccacggcggc caccgcgcca ccggccgccg tggcgatgcg ggtgcgcccg cgcggcttgc
     2101 ggtgggtgcc ggtgggacgc tgcggcacgg aaggcgcggg ccggctcccg ggggcgcggg
     2161 cggcgcgcgg cgcgccggtc gggacctgcc gccggccggg cgcggaggcg tccacgggga
     2221 agagggcgac gtcggcggga tcggggccgt gcagcggggg ttcgacgggc cgggagagcg
     2281 agtgggtcca gcattcgcag tcgggttcgc cggtgggcag caccggtcgg ccgcagatca
     2341 ggcactcgga ccggtcgatc gtcacactgc ccccctcccg atcgattggc agcgattatg
     2401 caccacccgt acgggggatg gcgggggtcg cacgggggcg gttccgggct cgcgcgcgca
     2461 tcgttccctg ggccatcagg cgtgcggcgc gggcgggcgg aacggccccg tgccgcggtc
     2521 gcggttccgg tcggcggcac gccccgtgac ctgcggaaag ccggtgcggg gccgcggcgc
     2581 ggagccggcc gggcccgagc gcggggccac ctcggcgggc cgggcggcgc gcgccgggcg
     2641 acgcgggggc cgccgggcca gggagcgtga atggcggccg aacttccggc gacggttgcc
     2701 caccggacga gggagggggt ggcgcgacgg gcccctcgtt ttgtaccgta gtaaaacaaa
     2761 gtggttccgc ccgcctcccc gaccgtgacg ggcggggcca ctggcttcct cctgtcccgc
     2821 accgacaccc gcacaccgcg ccaccgcccg ccccggcccc ggccttccct cccgatctgg
     2881 agcccgccac gatgtcgccc ctcacgctga cggcccgcgc actcctcctc gacatggacg
     2941 gcaccctggt caactcggac gcggccgtgg aacgcgtctg gcggacctgg gccgagatgc
     3001 gggacgtcga cccggtccgg gtcttcgcga tcatgcacgg ccggcaggcg cgcgccacga
     3061 tggcggacct gctgcccgag cggccggtcg aggagcacga ggccgacgcg gcctggctgc
     3121 tggcccggga gaccgccgac accgagggcg tcgtcccgat ccccggcgcc ggcgcgttcc
     3181 tcgacgcgat cgagcacgcg ccccacgcgc tggtcacctc ggcggactcc gggctggcgc
     3241 gggcccggat gtcggccgcg gggctgcgga tgcccgaggt ccggatcacg gccgagtcgg
     3301 tcagcgcgag caagccggac ccggagggtt tcctgaaggg cgcggccgaa ctcggcatcg
     3361 ccccggccga ctgcctcgtc ttcgaggact cggcggccgg catcgaggcg gcgcgcgccg
     3421 ccgggatgcg cgtgatcggc gtcggcctcc gggccgcgtc gctcgcgccg accgcctacg
     3481 cggccacgtt ggagaacgtg cgggtcgagg ccgcgccgcg cccgcgcccc gagggcttcc
     3541 ccccgtccga cggcctgatc cgcctcaccg tcaggccctg aaccgccgga atccgcacgg
     3601 ccggcaccct gtgggctcct gaacgcgccg gagcggtgcg ccggccgggc cctctcccgg
     3661 ccggcggacc gctccggcgg cggcgcgcgg cgcgccgccc gggacgcgcc cgctcaggcc
     3721 gcgggcactc ccgcgaacgg gatggagaag cacgccacgc gagccccggc gtcaccgggc
     3781 gggtgctcgt cgtgcccctc ggacgtgccc cgttcgtgca gcacgagcga acccgcctcg
     3841 cccgcgcgga acagccagtt cttgtggacc tcggcctgcc ccacgccgcg ctcgtcgacc
     3901 gtgaagtcca gccacacctc gctgtcctcg tccacgacgc cctgctcgtt ctggtagtgg
     3961 ccgcccgcgt cggccgggtc ggcgccgcag ggctcggtgt gcacgtgggt gccgtaggtg
     4021 tggccggggt cgaggccgag cgtggcgatg tcgatgagca tggagttgcc cctgatgccc
     4081 tgcgccacgt ggatctcgga cccggcgggc accagttcct cgttgtaggt caccgccttg
     4141 ggcaccgcgc cggcgcccgc ccccagcggc gcgaaccgcc cggcgtcgta cagcaggacg
     4201 tcgtcctgcc cggcggccac cgagctgccc gccgtcgcga gcaccgccgt catggcaacc
     4261 gcgcccgtcg ccagaatctt catcgttctc cttcgtggtg attgcctttc cctgggttca
     4321 ccctgcacag tgcagacttc gggaagcccg cccacacgca cccgcgtgca ccgcgcggag
     4381 gacccgggcg tacgctgtac ggcggaacca tcgccgtgca agagcgcgtc atatcgaaca
     4441 cgcactcgca tcaggcattt cggacgggga atcggggacc accgtgcagg agaccttggg
     4501 gatactgctg tacgccccgt ggatctacgt gatcgtcgcg gcctcgatcc tgctcgacgt
     4561 cttcgtgccg ttcctgccca gcggtgtgct cgtcgtcacc gcggccaccg ccgccgcggg
     4621 caccgccgcg gacgtcgcgg gcctgccgac ccccggcccc gaccaggccc tgccccacct
     4681 gctcctgctg gtgctgtgcg ccacgacggc gtccgtcgtc ggcgacctgc tcgcccaccg
     4741 cctcgcgctg cgcggcgggc gcaggttcga cagcgccatc gcccgttcgc ggcggctgga
     4801 cgcggcgcag cagcgcctcg cgacggcgct gcgcggccgg ggcggcggcc ccctcgtcgt
     4861 gctggcgagg ttcgcgcccg cagggcgcgc cgtggtcagc ctgggcgccg gagtggcgcg
     4921 ccgccgcacc cgcgagtacc tgccctggtc ggcgctcgcc gccgtggtgt ggaccgggta
     4981 cagcgtcggc gtcggctacc tgggcggaca cctgctcggc gtcagctggc tcagcaccgg
     5041 cctgtccctg atcgcgctca tcggggccgg tttcgtggcc gccaggctgc tgcgcccctc
     5101 ccccgcggcc gagaccccgg ccgcggtgcc gcaggccccc tgacggccca cgtctcccga
     5161 acgacacacg cctcccgaac gacgcgcacc cctcgttcgc acatccatcc gtccgcacgc
     5221 acacgcgttc gcgatgcgtt tccgtaattc ccggaagtgg ccgactccgg ccccggaacg
     5281 cgactctccg gtacccgcga aaactacgcg gaaaatcctc cgttaccacc cctgttgtgt
     5341 tttcgcgggc ggaactgaaa actgcccgaa atgcggcaag aatgaattcc gctgtgcgcc
     5401 cctgtgcgcc ccgcgtgctt cccgcacgcg cggacgcggg ttcactttcc gggggcctgg
     5461 ggacacggat atgaggaaac taaggggtcg gggggcgagt ccgagtcttt gcccgaggag
     5521 gcaccatccg tgatccggtt actgttcgtg cacgatgaca ccctgctgcg ctgcggtttg
     5581 acctcgctgc tgggcgcgga ggtggacatc gagatttcct ccctttcctg ggaggcactg
     5641 accagggcgg agccgccgcc accgggcacg gtacggctcg cggacgtgac ctgccccggg
     5701 ttcgcccggt acgcggacga aacggttcgg cagacgggtg ccgaggacga gcacggcctg
     5761 gtcgtcctgg caccggcggg cagacccggg ctgctgaccc gggcgttcga ggcgcgcgcc
     5821 ctcggctacg tcagcaagga ggccccgccg cagcgcctgc tcgacgccat acgcgcggtg
     5881 gccaaagggg gccgttacgt cgacgacgcg ctcgcctacg acttcctcag cgcgtcccgc
     5941 atgcccctga ccccccgcga gctgcgggtc ctcgccctcg ccgcggacgg cgcgccggtg
     6001 ccggagatcg ccggcgagtt atggctcgcg gagggcacgg tgcgcaacta cctggccgcc
     6061 gtcatccgca agaccggggc ccgcaaccgc gtcgacgcca tccgcatcgc caggagcgcg
     6121 ggctgggtct gaccagcccg cggccaggtc gcggaagagg gcggatcgat cgagcagttc
     6181 gcgcggggtc ccgctgtgcg cctcggcgcc gtcgagcacc agcacgcggt ccgcgcggcg
     6241 ggccgagctg atccggtgcg cgatcacgac gagcgtgccg ccgggacggg cggcgaaggc
     6301 ccgctccgcc cccgcctccg cggccggatc gaggtggcac gtggcctcgt cgagcagcgc
     6361 cacgggcgcc ggggagagga aggccctggt cagcgcgagc agttgccgct cccccgcgga
     6421 cagcgcggcc gggtcgacct gcccggccgg gccgccgagc cggtcgagca ggtcgcccgc
     6481 gcccaccgcc tcggccgccg cggtcagcgc ggcggccggc gggggcgcgg cgcgcaggta
     6541 ggagaggttg tcggcgacgc tgccgcggaa cacgtacgcc tcctgcggga tcaggacgcg
     6601 cagcgcggcc agttccgctg ccgtgcgtcc ggccaccggc cgcccgcaca gcgcgacccg
     6661 gccggcgcgc ggcgcgagca ggccggcggc cagcgcggcg agcgtcgact tccccgcgcc
     6721 gctcggcccg acgacggcca ggtgcccgcc gggtggcacg gccaggtcga ggccgtcgag
     6781 cacggggtcg gcccggccgc cgtaggcgaa cgtcacaccg cgcagctcca cggccggccg
     6841 ccggcgcgcc gcgcccaccc ccggcgcgcg cgcctcccgc gcgggcgccg gtccggcccg
     6901 ttccgccggc gcagacccgg acggctccac caccgacccg gacggctcca ccgccgcccc
     6961 ggcccgttcc cgcgccgact cggcgggcgg gccctgcggc ggcagcgggt cggtgcgcag
     7021 ccgggcgatc accacggcga gccgggtgcc ggcgctgccg acaccgccga gcagcgcctg
     7081 caacgcgggc agcagggcct gcgtgacgaa cgtgagcgcg ccgagcaggc cccccggcgt
     7141 cacgccgttg cgcagcaacc aggggccgag gaacagcagc agcaggaccg gcagttgacc
     7201 gccgataccc agggcgacca cgcgcacggc cccccagcgg ccgagcgcga gcgcggcggc
     7261 cagctccgcg tcgacgcgcg cgccgacggc cgcctcggcc cggccccgca cgcccgcggc
     7321 cgtgatgtcc cgcagccccc cggccgtctc gccgaacgcg tcggccagcg cctcgtccgc
     7381 gaccagcacc gcgcgctgcc gcctggccag cgggcgcagc gaccaggcga acagggcgag
     7441 cgcgagcagc agcgggccga gcacgacggg cagcagcacg ggcgcgagcg aggcgagccc
     7501 ggccagcgag cccgcgagcg tgcacacgaa catctggagc acgagtacga gtccggcgaa
     7561 gctgtccctg gcgatctcga cctggtgcgt cagccgggac acgtccgcgg tgccgctctc
     7621 cggccgcccg gcgcgcacgg cgcggtgcag cccgcgcgcg acgacctcgc gcaccaggcc
     7681 gtcgcgcagc ggctcggcga gcgcccccac ggcgcggtgc acgcgcgcgg tgccgaacgc
     7741 gccggccagc acgccgccgc cggccgccgc cagccaggcc aggccgacgc cggtgcgccc
     7801 ggcgaggaac ccgtcgtcca gggcgcgcgc caggccgtag ccgaggagga acgtctgcgc
     7861 ggccggcagc aggccccacg cggcgaggac ggccaggggg cggcggttgc gccgcaggta
     7921 ccggaacacc gcgtggtcac gcaccggccg cacctcccgc cctcgcctcg ctcgtcccgg
     7981 cggcctcgcc gcgcgcgggc tcgtcggccg cccacagcgc ccggtagtcg gcgcgggccc
     8041 acagctcgcc gtgcggcgcc agcgcgcgga cgcggccctc gtcgagccag gccacgaggt
     8101 cggcgcgggc ggcggagcct gccctgtggg ccacgaccag gcgggtgcgg gccgcggtgt
     8161 gcgcggcgag ggcgcgggcc acgtgcagtt ctgtgaccgt gtcgaggctc gatgtggcgt
     8221 cgtcgaggat cagcagccga ccgccgcggg cgaacgcccg tgccaggccg agccgttgca
     8281 gttcgccgcc ggacagggga acgccgtcgc agcgggtcgc gtaccccgcg gggagggtgc
     8341 ggatgaagcc gtcggcgcgg gccgcccgcg ccgccgccgc gacgcgttcc ggcggcggcg
     8401 cggggccggg cccgaggccg atggtggcgg cgacggtcgg ggccagcgtg ccgccgagca
     8461 gcgcggggcg ttcgaacgcg tagccgactt ccgcgcgcag cgcgtcgggc gccaggtcgg
     8521 tgacgggcac gccgtcgatg agcacccgtc ctgcgtcggg ctcggccagg ccgccggcga
     8581 gcgcggcgag cagcgacttg ccggcccccg agcggccgac gagggcgacg gtgctgccgc
     8641 ccggcaccac caggtcgagc ccgcgcagca cctcccgccc gccgcgccgc gcgctcacgc
     8701 cccggaactc gacccgccca gggccgccgg gcggcagcgc cgcgccgccg tggcgctgcg
     8761 gcggcacggc cagcacctcg ccgacgcgca cggcggcggc gcgggcgcgc accaggcggt
     8821 tgaggtggcc gacgaacagt ccgacgccgc cggcgagcgc ggcgtacctg gccgccgcga
     8881 gcaggccgcc gacggtcagg tcgccgacgg cgagcagcag cccgccggtg gcgaccacgg
     8941 ccagctggag cagcggcgtg agcgcggcgg cccggcccgt ggcgcgggcg ttgacccgcc
     9001 acatccgcag gccgtgctcg ccgagccggg gcagcgggtc gagcacgcgg cgccgttccg
     9061 cctcctcggt gcccgcggcg gcgatcgtcc tggccccgcg cagcgcgtcc accaggcggc
     9121 ccgcgatgtc agcctgggcg cgctggtagc cggcgaacgc gtcgcccgcc gaccgcgcga
     9181 acgcccgcag cagcagggcg agcagcggca gtcccgcgag gaagaccagc gcgagccgcg
     9241 cgtcggtcac ggccagggcg acgatcgcgc ccagcggggt cgcggcggcg gcgaaggccg
     9301 cggccagggc ggcgggcgcg gcgcccgcgt ggacggcgtt ccccgtggcc cgggcgacca
     9361 ggtcgccctc gggaaaacgg gccgcggccc ccgggcccgc cgccagcagg tgccgcagca
     9421 gccggccgcg cagccaggcg gcgccgtgcg cgtcggcgcc ggcggtgagc acggtggtga
     9481 gcacgccgac gaggacctgc gcgatgacca ggcccgcggt cagcagggcc gggccgccgg
     9541 cggcgtcccc ctcggccagc agcgcgtcga gggcgcggcc gagcgcggtg ggcagcgcga
     9601 gcgccacgcc cgcggcggcg agggacagcg cgaacagcac ggccatgcgg ccggcgccct
     9661 gccgggccgt ggcgcgcagg gtcgggtcca gaaggtgcgt cggcatggcg cttcgctgct
     9721 ccttcgcggg aacgggcgcg gccccgcgct gctgcgcggg gccgcggtgt ccgccgggat
     9781 gccccgggcc tcggactcag agacagagga tgacgctgtt ggagctgtgg gtgtcgcaga
     9841 tcagcaggct gaggctgctg aggtcgccct cgccgccgcc gccggtggca acctcgggct
     9901 ccatgctctg aaggtcaaga agggacatgg cggttcctct cttcgagaag gtgaacgggt
     9961 cgtgcacggg cggccccgag cggggcgccc acggcctccg tcaggcggac ggaggccgtg
    10021 ccttggggtg ccgcgggtgc ggcaggaacg gcaggcgcgg caggccggcc gggtcccccg
    10081 gccggtgcag cgcggtgccg agggccagca ggcagccggc ggtcccggtg ccgaggtcca
    10141 tcgacaggcg catcatctgc tctcccggga aggcgagttc gccgtcgtag gccatcgcgt
    10201 accagccgag cgcgtcgatc tgcgcggcga gggcggcctc cggctcgggc ccggggcgcc
    10261 gaccgggcgg cgcgggcctc gcggccgtgc gcgccaggtg ccagatcatg ccggcccggc
    10321 cgcggaacag gccgggctgc gcgtagtacc gcagccgcgc ggcgggcagg atgtccgccg
    10381 cggcccgggc caggtcctcc tcagcgggca gtcccgccga tgaggccgcg gccaggtagt
    10441 cgtccagcac cgccgcgatg ccgacactgc cctcgccgag gtagggcatg agccggtcgc
    10501 cctcgtcgac caggagcgcc ccggaacggt ccgcccggca gtgcgcgagg tcgcgccgca
    10561 gcgcggcggc ggccgtcgcg agcagccgga cctcgccggt ccgttcgtac cggcgcagga
    10621 acagcagcgc caccccggtg gccccgtgca gcagaccggc cctgcggtgg ccgcgcggct
    10681 cggcgggccc ggcgacgtgc cgcgcggcga gttccgcggc gcggccggcg tgcacggcga
    10741 gcgcggggtt cccggtgtcg gcggccaggt cgtccaggac gagcccgatc ccggcgaggc
    10801 cgccgtgcag gtgggcgggc agccgctccc agccctcgcc gagcgcgcgc gtcgcgaggc
    10861 cgagcgcggc ctcggtgtgc ccgaggcggt gcaggacgtg cacgacgccg aacagcccgt
    10921 cgtagagccc gagcggggtg ttgcgcggcg gatcggccgc gcggcgcagc agccagcgtt
    10981 cgccctcggg atgccgcggc gcgccggtct cggccagcgc gtacagcacc ccggccgcgc
    11041 cgtgcgccag gccgagcccg ccgccgggcc cgaactgcgc gatgtcgccc gggtagagcc
    11101 ggtcctcgcg ttccggggtg gccgaggcca ggatggcgcg ggccatcgag gcgcgggccg
    11161 ccggccagtc gcccggctcg ggcggggcgg ccgggcgctt gcgcgcgttc cggtcctcgc
    11221 ggccctcgat ctcggcgacg gcctcgtcga agaacgcggc cggcacgtcg gggaactcgc
    11281 ggcgcgccac ccgcgccagg tgcgccgcct tgtcccggtc gacggcgaac agcgtggtca
    11341 tcggcaggaa cagcgcgagc cgcaggcacg cgagcgcgta gcggtcgacg gcgaacccgg
    11401 tgcggtcggc cggggcgatg aaccccgggt gcgcgacgac ctgccgcgcg ccgtcctcgg
    11461 ccggggccgc ggcctcgaag tcgagcagcg tcacggaggt ctcgtcgggg gcgaccatga
    11521 tgttgtacat gtgcaggtcg ttgaagacca ggccgcggcc gtgcagggcg gcgacggccc
    11581 gctcgacgtt gcggtgcacc gccagcgccc accgggtgta ggaggcgacc gcgtccggcg
    11641 ccgggtccgt ggcgagcagc gggtggcgtt cggcgaagaa cgcgttgagg gtgcggcccg
    11701 gcacgtggtc catcaccagg aaccggtgct cgccgacggt cagccagtcc cgcaccccgg
    11761 gcgccacggc cagcccggcc agccggtcga gcgcggcctt ctcccgctca agccgggtga
    11821 cggcgtccgc gccgtccgcg gcgagcccgg cgtgcgggcg cgcctccttg agcaccaccg
    11881 cgtcgccggt gcgggtgtcg gtgccccggt agacgccgcc gccgttggag aagtgcaggg
    11941 cgctgtcgat gcggtagggc agttccgcga cggtgacctc gttgcgggcg gcgaggtgcg
    12001 gggcgaggaa cgggggcagc gtcacccagg cggggacgcc gaacgcgggc cccctgcggt
    12061 cggggacgag acggccctcg gcgttctcga tggcggggac caccgcgccc gtgccgtcgt
    12121 cgcagtagcg gggaacgaag ccgccgtacc tgacgtacag cgggccgcgt tcccagcgca
    12181 ggtcggtgag gatgtacggg cccggctcgc ccgccagttg gtccccgaga tccgtcagga
    12241 cggtgcgcag cgcggcctcg tccgccgggt agatcgtgac gaacttgccg ctcgaatggc
    12301 ggcccgcgta tttggagttg cgcaggaaca gcagatgcgc cgagggcacg aatttgaacg
    12361 ggatgcggcg cggcacgcaa tagtcccaga ctttcgccgc ggtcttgtcg gcgttgtcga
    12421 ggcaggcgga cacgtggatc ttccagccct gcggcggcgt gatgccgtcc cgcggctgga
    12481 gatgcagcca gtcgccgaaa cgctcggaga gccagccctg cggcaccggg cgccgcgccg
    12541 tttcgtacag accttcctgc ccgctgcccg cggcgtcgcg cgaggcggcg cgttccggcg
    12601 cctcgtagaa atgccggtcc accaggcaga aaacctcgta ccgcttgtcc attgccctcc
    12661 ctcgggaagt gacaatgagg tttccacggc ggaaggccgg tcagacagtc accggtgtca
    12721 cgtcggggac gtgaagaacg cacacgtttc cctcacaggc ggccgacacc gccgtaccag
    12781 gacacgtcct cgcaggaggg ccgctccgcc tccggctcgg tggcgcgcca ctcggagacg
    12841 atctgtatcc cgggctcgat cagctcaagg ccggtgaaga actcgccgaa ccgctccttg
    12901 ctccgcagcg tcaacggcac gccgtgcgaa cggtaggcgg cctgcactcc catcgcggcc
    12961 tgcggggaga tgtcggccgt gccgtgcgag agcacgaagt ggctgccggg cgcgaggaca
    13021 tcggcgaggg cgcgcacgat gccggccggg tcgtcctcgt cccttatgaa gtgcagcacc
    13081 gcgaccgcca gcacgccgac cggctcgtcc gggtcgatct gctccctggt cctggggtgg
    13141 tggaggaccg cgagggggtc gcggatgtcg ccgtgcacca cggtggtccg ctcgttctgc
    13201 tccagcatgg cgccgccgaa cgccagcacg atcgggtcgt tgtcgacgta gacgacgcgc
    13261 gcctcggggt cggcctcctg ggcgacctgg tgcacgttct ccgtggtggg caggccgggg
    13321 ccgaggtcga tgaactgccg gatgccgacg tccagtacga ggtggcgcac ggcgcgcgcg
    13381 atgaacttgc ggttctcctg cgccgcgatg cgcagcgtcg gcgcggcggc cagcgcgttc
    13441 tccgcggctt ggctgtccgc cgcgtagtag tccctgccgc ccagcaggta gtcgtacatc
    13501 cgggccgaat gcggtcggtc ggtccgggga acgaccggcg agtcaccgtt cacgggcacg
    13561 cccctccatg ctggttgaac gccggatcaa cggctcgaag aatagtgcga tttgcggtcg
    13621 gtcgtcgatc tcggcgcacg ccgcgccccg gccggaaccg gcggcgctcc cgccggccgg
    13681 tggccccggg gcggccccgc cgaagggcag tcgggcagaa cccatgggag atcaactcct
    13741 ctcccggcac ctcgatcgcc cgagcccgcg ggccgcgccg tcgcggcctc ctggaagtcc
    13801 cgccagtcta gcgcgcggac ccctcgcccc acgtgggccg aagggcccca ttcaccccag
    13861 cacgaaggcc ccggaccagg gaagatccgg ggccttctgt cgtagcgggg acaggatttg
    13921 aacctgcgac ctctgggtta tgagcccagc gagctaccga gctgctccac cccgcgtcgt
    13981 gtgcaccact ctacgccatc cccggccccc ctccgaccac accacccccc ggccccggcg
    14041 caccccccgc gccgggggcg accggagccc gccgcgcgcc gcgctcgcga gaccgccggc
    14101 cgagcccgcg aagcgcgact ccccgccgcc ccgggccggt agggtcaccg gacatgcgcc
    14161 cggtgagccg taccagcgaa cgcctcctgc tgcgggagtt gaccgttgac gacgtggacg
    14221 acgtccacgc gatctacggc gacgccaccg cgacggaaca cctgtccttc gaaccgcgaa
    14281 gccgcgacca ggtcgcccac atcgtggccc gctcgatggt ctccgcgttc gccaccccac
    14341 gtgaggagta cgccctggcc gtgtgcgaac gcgccggcgc acgcctcgtc gggtacgccc
    14401 ggctggcgat ggacccgcac gggcagcggg cggcgaccat cggcttcgcc ctgcgccccg
    14461 acgtctgggg cgcgggctac ggcaccgaac tcgtccgcgc cctcgtggcc ctcggcttcg
    14521 aggacctggg cctgcaccgc ctctgggccg cgagagcacc agagaactcg gcctcccgaa
    14581 ccgtgctcga ccgggccgga cttgtcgaag agggccgcat ccgccaccac gtccacgtcc
    14641 ggggcgcctg gcgcgactcc gtcgtccacg cgatcgtcaa cggcacctga cgcaccgacc
    14701 gcgcgagccc ggcccaccgc ccgcagaacc acgcgcgccg tccggacaaa cccggccggt
    14761 ctcggcgccg aaacagcggc ccaccgctga gcgccgccct tacaaggcgg acgtcggcgg
    14821 ttggggactc agggaagcgg acgctgcccg ccggtgctca ggtgccttct gacctgtacc
    14881 gctgaagtcg cgccaacgct tcctccttgg tcagcgcgga cacggtctgc tcgggcagga
    14941 cccggcccgc cggagatgcc atactcgaag tatggctacc cgcaagatca ccgtctccgt
    15001 tccggaagag ctggtggaat cgatcaagga acgcgttcac ccgcgtgggg tctccgccta
    15061 catcgccgcc gccgccgcgc accgggacgc catggaccgg ctgcgcgagt tggccgaacg
    15121 gctggaggag gagcacgggg ccgtgacggc ggacgaggaa cgagaagcgc acgcccgcat
    15181 cgccgccatc gacgactggc acgacgagca gcgctcgcgg ccaggcgggg ccgcgtgagc
    15241 cgcaccgcca gaggaaggca ggaccacgcg cgcaagcgtg tcttcgtgtt cgactcgaag
    15301 gccctttccg aggcggttcg gggtggccgg gaggtgaccg ccctgatcaa gacggcttcg
    15361 cgactcaaca ttccggtcat cacttcggcg ctcactactg tggcagcgtg ggacccccgg
    15421 ggaacatcgc ggcaggcgcc ctggcactgg acgttgtccc gcgtccgtgt cgtgcacacc
    15481 gacgaccaag tgatcgccac ggcgcgcgag atgctcaggg cagccggcct gcacgggcac
    15541 aagtacgcca tcgacgccgt cctggcggct gtggccggac gggaagccgc gcaaggggct
    15601 caggcgaccg tcttcacctc cgacaccgac gacatgagcc ggctcctcgc gggccgctcc
    15661 gtgcgcgtcg agaaggtctg atgccccgcg ccccccggtt cggccgccgc gcgtcgtgat
    15721 caccttcgtc gccgcccgtc ccgcggaaag gcgtctcgga cggccgcccg cgttcggggc
    15781 gcggggcgaa cggggacgag gtggacttca tgggggcacc ggtggcttgg ttggccgaac
    15841 ggtggaacga aagggccggt gggtgcagac gggttcgaac cgccgacatc cgccttgtaa
    15901 gggcggcgct ctaccgctga gctatgcacc cgggaatcgg tcccacagcc tacacggccg
    15961 cccgggccgg ggcggcaacg ccggtcatcc ccccgcttcg cggggctgat gggagaatgg
    16021 gcgtgggacg gaacggtacg ggcacggggt accggaacac cggcatggcg atccacctgc
    16081 ggggagtgga acacgtgaca gcgacgcgca ccgcgaaaca gttggccgct ctcctcctgc
    16141 tgccgccgct gtccctggcg gccgtcgcgg ccacgctgcc cggctcgttc accggcggcg
    16201 gcacgcggcg ctggggccgg ggccgggtgg aggacctgcg ggccgaggcg caggaggcga
    16261 aggacgccgc ggcggcggcg ttctacgcgc tggacaccgc gcagcgcgac ctgcggatca
    16321 ccgtggagac gatcaccgcg gccgacgaca cccgggaggc ggcgcgggcg gcggcggagt
    16381 tcgccgcgtt cggcgagcgg atcgaccgcg tcagccacgc gtacatcacc accatggacg
    16441 cccacgacct ggacggcgag gggctggacg ccggcgcggc cacccgggcg cggcaggagc
    16501 tgcgcggcgc gcgcgacgag ctggaccgca cccggcggga cctcgaagcg ttcgggcagt
    16561 ccatcgggcc gctgcttgag cgggccgagt cgcagctggc gcaggtcgcg cccgcggtcg
    16621 aacgggccag gcaggcgctg cgcgcggcca ccgaggcgct ggacgcggcg cgcgccgccg
    16681 gcttcggcgc cggggacctc gccgcgtcgc tcgccgcgct cggccccgag ttgcggcggc
    16741 tgaacgaagg ggcggggcag cacggcgtcc agccgacgat ccgccgcgcc gaggacgtgc
    16801 ggcggcgggc cgaggcggtc gcggcggacg cggcgcggct gccgcagcgg gcggcggaga
    16861 tcgaccggcg gctgtccagt ctgcgcaccc gtgcggaggc gatcgtgacg cgcgccggga
    16921 aggtggagcc ggtgctgagc gagttgcgcc gccggttcag catggcgtgc tggcaggacc
    16981 tccagcgggt gcccgagcag gccgcgcagt cggtgcggca ggcggagcag atcctcgacg
    17041 aggcgcggcg ggcccgcgac gagcagcgtt tcgaggacgc gacgacgcgg ctcacgacgg
    17101 tgcacgcgct gctcggccgc accgacgagg cggtgtcggc ggccggggag cggctgcgcc
    17161 ggctgaacga ggtgtcgttc gacccgcgca aggagatcga caggacccgg ttcgtgctgc
    17221 gggacgcgca gcggctggcg atggcggggc gttccgtgcc cgagccgcgg cacgcgcgac
    17281 cgctggacgc ggcggtggaa cgcctcgacc gcgccgtcgc ccggctggag agcggggggc
    17341 gccaccccga ctactgggag ttcctgaccg agatggacgc ggtccgcagc gcggtggccg
    17401 cggtggtcga ggagatcagg gccggtcgct agagcgcggc ctccaccagc gccgtcgcgg
    17461 cgatgtgcac ggcggctgcc gcgtcgtgcg cgcccgcgat ggaggtggcg acgatcgcgc
    17521 cctcgtggag gctgagcagc tgggtggcca gggtggccgc gctcctggcc ccggcctcgg
    17581 tgagcaggcg caggaacagc tcgtgcagcc actgcttctc cgccacgacc acccggcgcc
    17641 cggcgtggtc gggctcgggc agctcggcga aggcgttgac ggcgctgcat ccgcgctcgg
    17701 actccgacac ccactcgggc agcacgtcga acggcacgag cacgcggcgc accgggtcgt
    17761 ccggggtggc gtcgaggcgg gcggtgacca ggtcgcgcca gcggcggtcg cgggtctgga
    17821 ggtaggcgac gacgagggcg tccttggaac cgaagcggtt gtacagggtg cgcttggtga
    17881 cgcccgactc ggcggcgatg gtgtcgaccc cgaccgcgtg gatgccccgc tggtagaaca
    17941 actcggacgc gacatcgaga atccgccggg cacccggcgt gagctggtcg gcgtcggtca
    18001 tgccgcatca cctcttgact tcacagatct gtatagttac cgtggactca cacttcacag
    18061 accagtgtac ttcggagggg caccatgcac gcgatcgtgc gacagctgat cgaaggtacc
    18121 cgtgcgttcg gccacggcat cgcggccggc accgccatac ggcacagccg tactccgggc
    18181 cccgccaccg ccgccgccac cgcctggacc ggcaagcggc agggcatagg ccgacccgac
    18241 ggcgcggccg tgcccgtcgg cgccgaccag caccaccagg cgggggcagc gcgttaggtc
    18301 ccggtttgcg cgggtacgcg gggaaccttc gaggaggttc ccatgggtac gttcacgaca
    18361 agtggttcac cacggctgcc gagcacgggc ccgttggggc tgttgcggcg ggcccgtctc
    18421 gatgagcacc tgccggtgga ccgccgcctc agccgcgtct accggatcgg ggccgggctg
    18481 gtgggcctcg ggctggtcgt cttcggcgcc ctggggatca cgcagaacct ggacatgttc
    18541 tccacgggcg acgacaccat ctggagcctg aacaccaacg gggcgctgag ctggctgtcg
    18601 atcgtggtgg gcctggtgct gttcttcggc atggtccgcg ggggcaacct cgcctccacg
    18661 ctgaacatgc tgatcggcgc cgcgttcgtc ctcagcggct tcgtcaacct ggccctgctc
    18721 gaaacgggcg ccaacgtcct caacttccgc atgcccaacg tgatcttcag tttcgccgcc
    18781 gggctgctgc tgatgtcgtt cggcatgtac gggcgggtca gcggccggct tccgcacgac
    18841 aacccctact ggcgcgtccg gcacccggag gcgggcgagg acgcgcccga gcggcaggag
    18901 cacgccgagc acgggcgccg cgtcctggac gaacggcagc gcgaggagac ggcgcgttcg
    18961 gcctcggggg cggtgcatcg gggcgcaccg gaccggcacg ggtaggttgc cgcccgtgcg
    19021 gggccggaca gcgtgccgtc cagccccgca cggacccgac gagctgatcg tccggccccg
    19081 cacggacccg atgatcagcg ctgcatcagg gcgaagactc cccagcccag atactcacgc
    19141 gtgaagcgcg cgtagcgtgc gggctcggtg gtgagttcgg cccgtacctc gggcgccagt
    19201 tcgtcgtccg ggttcaggtc gagccagcgg cggaggttga gccactgggc cgcgcagtac
    19261 cggtcccagc tgtcctgatc cgccagcatc atctccacca cgtcgtaccc cagctcgccg
    19321 aactgctcga tcagctcggg cagcggcagg aagtcggcca ggctggtggc gtggcaggct
    19381 tccgcgacct cctggctcgg cggagtccgg cgccagtagg gttcgccgat cagcatcagt
    19441 cctccggggc tgaggctgcg gctgagcagc gcggccgtcc cggcgacgcc gttgccgatc
    19501 caggtggcgc cgacgcacgc ggcgaggccg accggctcgt ccgcgacatg accggaggcg
    19561 tcgccgtgga cgaagtccac ccggtcggcg acgccgagct cgacggcgcg ggccctggcc
    19621 tgctcggtga acaccgtgct gaggtccacg cccgtgcccg tgaagccgag gtcacgtgcc
    19681 caggtgcaga gcatctcgcc cgagccactg gccaggtcga gcacccgggt cccggcgggc
    19741 aggcggagcg cctggcccag ggccgcgagc ttgtcggggg tcagcgggtt gtggatgcgg
    19801 tgactgctct cgcggatggt gaagatgcga ggaaggtcca tggtggtttc tcttgtctgt
    19861 cgggcccggc gacggccgga ccggtcgagg gcacgcccca tgcgtgcgac gttcttttcg
    19921 gccgtttccg ctcgtccgct cagccgcacg tcggcgcgga ggcggcgcac cgtcatcggt
    19981 gccggggcgg gcatccgccc gcgcgccgtg cgggccgcgc cgggccggca agcggcccgt
    20041 cggcgcggaa gcgggcgggg gaaagggcgc gttccccgcc ccggccgcgg gcggccggag
    20101 tcaggacacg cctgggagag agcacgagga aaggcgggga agcaagtcga tgagacaacg
    20161 tggagaccct ggggaagggg cccctccgga cggcacggca gggcggcagc tcccgctggg
    20221 aggacgccgg gtaccggtca ggacgaggcc cgggacgtga ggatgatccg ggcaccgcgc
    20281 acagcggtgg tctccacggc agtcatcaac tcacctcact cgggctccgc ggcggacctg
    20341 gtcggcgccg cggccttcag ggtaacagcc cgtggcgccg tcgccggggc cgcctgcccg
    20401 caccgggggc gtccgcccgg cgtcagcggg tcagccgggc agccgggcga ggaacgcccg
    20461 cacgatctcc tcgccgcagc cgacgccctc gccctccagg gccgtgacgt gcggggcgcc
    20521 ccagccctcg gccgccagct cgccgtgccc gggccgccag ccgtggtcgg ccgcgagcag
    20581 caggtcggtg tcgagcagcg agtcgccggc cgcgagcacg ctgcccgccc cggtgcggcg
    20641 gacgatctcc gcgacggcgg cgctcttggt gagcgggcgc ggcacggcgt acagcttgcg
    20701 gccctggagg gacacggtcc agccacgcgg cccggcccag tcggccagct ccttggccca
    20761 cgtgtcgggc agcagcgccc ggtccaccac gaggtaggcg aacaggccct ccgcgtcgcg
    20821 ttccctcagc agccacgcgg gatcggccgt gcggcgcagg tggtcgcgga cctccgcgag
    20881 cggtgcgcag tccgccgcga ggcggccgag caccgcggcg tgccagtcct cgtccgtgcg
    20941 gccgtcgacc agcaggtggc cgccattggc gcagatcgcg taacgcggcg cgggccccgg
    21001 caggttgacg cgcaggtact gctcgcgggt gcgcgtggtg gtcggcacga agaacgcgtc
    21061 ggtcctggcg gcgagttccg cgatgaggtg ccccgcggtc tcggtgacga acgactgcgg
    21121 tcgcgcctgg tagacctcca cgcaggtcag gcgcggcgcc cgcgcgtccg gcatcccgag
    21181 cgcgagcgcg gcggccgagt agatcagcgt gcggtccagg tcgctggcga caacggtcgg
    21241 cgcaccgggt gtcacgtccg gcgtcgcctc ggtgctcgcg ggaatcacgg tgcggccttt
    21301 ccgtcggcgc cggtcgcgcc cctggtgtag cgcgggtgga tgagcccgac gcaactgtag
    21361 ggcaggtcgt cggtctcctc cacgggcacg ccgcgctgct cggcgagcag gcggacgtgg
    21421 tcgaggtcgg ctccggcgcc gcggcgggcc aggacgcgcc agggcacgcg ccgcagcagc
    21481 acccgcgtgg tctccccgac gccgggtttg acgaggttga cgtcgccgat gccccactcc
    21541 tcgctgatgc gctccaccgc gcgccagccg gcccaggtcg gggcgcggtc ggcggcgagc
    21601 agcgcggccg tgtcggcggc caccccggcg accacgcccg ggtcggtgaa gtgcgcggtg
    21661 atcgtgtcga ggaagtggcc agagaggtcg gagccggcca gttcgcggta gtgcttggcg
    21721 ccgtggaagt cgtgcgggcc gacgaggtcg tcccgcagca ccgtgcggga gatcaggccg
    21781 gacaccgtgg agttgaggca ggcggacggg atgaggaagt cctcgcgcgt gccgtaggtg
    21841 gtgacgcagc cgcccgggtc cgcgaggacc gcgagggacg ggtcgaagcc ggggaacggg
    21901 gccagcgccg cggccagttc gcgggtgatg gcgcccttgc cggtccagcc gtcgacgaag
    21961 acgacgtcgg ccgggtcgtg gtgggccgcg agccagcgca gggcggtggt gtcgatgccc
    22021 tggccgcgga cgatggagat ggcgtagtgc ggcaggtcga ggccgtgcgc gtgcgcggcc
    22081 cagcggcgca tgagcacgcc cacgggggtg ccggccctgg ccagggagac cagcacgggc
    22141 ggacggccgg gcccggcccg ttccgcgagc acggcctcgg tgacggtccc gacggcgcgg
    22201 gccacgcggg cggccgaggc gtcgagcgcc tggtggaaca gccgctggta ctccgggctc
    22261 ggctggtatt ccacgggcag cgactcggcg tagtgggcgc cgccggactg gatggcctcc
    22321 tcgcgttcct ccgccggggc ctccagggtg acgtcggaca ggtcctggag gagccagccg
    22381 acctcgtcgg gcgcgtagct ggagaacgcg gggccgcgca gcgggtgcgg cagcgagggc
    22441 accacggtga gcagcaggtg cggggtgtgg gcgccgagcc gggccagcag gccgtcgggg
    22501 gcgtggagtt cgagggtgtc gccggccgcg tcggtgacca cgacgacggc gtcccagtcc
    22561 cggccggcca cgttgtagac gaaacgcggg gcggggccgt cggcggggcg gtcgtgcgcg
    22621 gcgaagagca ggcggctgcg tatcgcgtag cc
//
